124 results on '"Daniel, Craig"'
Search Results
2. Setting a theater: Establishing transit center MK (Mihail Kogalniceau)
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O'Connor, Jack, MajGen and Daniel, Craig A., Maj
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UNITED STATES - Military Relations - Romania ,MOVEMENT CONTROL ,LOGISTICS - Army - United States ,MANEUVERS - Army - United States ,ARMY, EUROPE - Abstract
illus
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- 2015
3. Comparison of TP53 mutation prevalence in human blood cells from lung cancer patients and control subjects
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Patrick Gorman, Erin Crawford, Daniel Craig, and James Willey
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Lung Cancer ,TP53 ,Biomarker ,Research ,Hematology/Oncology ,Medicine (General) ,R5-920 - Published
- 2023
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4. Validation of Airway Epithelial Cell TP53 Biomarker for Lung Cancer Risk
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Daniel Craig, Erin Crawford, and James Willey
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Molecular Oncology ,Lung Cancer ,Biomarker ,TP53 ,Hematology/Oncology ,Research ,Medicine (General) ,R5-920 - Published
- 2023
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5. Saving the Church of England : John Edwards (1637-1716) as dissenting conformer
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Norman, Daniel Craig
- Abstract
Following early retirement from parish work, Edwards undertook a mission to defend and preserve the Church of England. Against those who sought to make optional those doctrines traditionally considered as essential for Christian orthodoxy, such as the Trinity and Incarnation, Edwards was uncompromising. Removing foundational ordinances of Christianity would destroy the church. To counter Arian and Socinian threats, Edwards entered the pamphlet wars, engaging some of the leading heterodox intellectuals of his day, including John Locke, Samuel Clarke, and William Whiston. Edwards was also committed to church unity for those who accepted as essential those doctrines delineated in the Apostles', Nicene and Athanasian Creeds upon which the XXXIX Articles were based. Though a committed Calvinist, he willingly subordinated his theological preferences on non-essentials to greater principle of unity by respectfully remaining in the church dominated by Latitudinarians and others who did not share his Reformed theology. Leaders on all sides of the seventeenth-century dissension paid lip service to church unity, but failed to act on it. Edwards practiced genuine toleration within the traditional bounds of orthodoxy but he would not extend his tolerance to define the church out of existence. Toleration, after all, is a weak version of Christian love and it was clear to Edwards that lack of love was the basis for division. Most contemporary references to John Edwards describe him very briefly as a rude, extreme, and slandering Calvinist who had a bitter debate with philosopher John Locke, the champion of reasonableness, peace, and toleration. This thesis does more than upend that synopsis. Although Edwards was not always the most diplomatic opponent, a close evaluation of his works demonstrates that he was most often respectful, fairly tolerant, and careful in his accusations. Had others followed his example, Church of England schisms could have been avoided.
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- 2020
6. HIGH-RISK NON-MUSCLE INVASIVE BLADDER CANCER WITH VARIANT HISTOLOGY OR OTHER SUBTYPES NOT A PREDICTOR FOR PROGRESSION IN BCG-TREATED PATIENTS
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Calkins, Daniel Craig, primary, Davaro, Facundo, additional, Guske, Chris, additional, Sirard, Richard, additional, Li, Roger, additional, Gilbert, Scott, additional, Sexton, Wade, additional, Spiess, Philippe E, additional, Poch, Michael, additional, Yu, Alice, additional, and Zemp, Logan, additional
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- 2024
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7. Bison Goring Resulting in Abdominal Evisceration and Cervical Fracture: A Case Report
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Miles, Gayla, Quinlan, Ann, and Daniel, Craig
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- 2022
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8. The Use of Different Sepsis Risk Stratification Tools on the Wards and in Emergency Departments Uncovers Different Mortality Risks: Results of the Three Welsh National Multicenter Point-Prevalence Studies
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Harry J. A. Unwin, MBBCh, BSc, Maja Kopczynska, MBBCh, BSc, Richard Pugh, FRCA, Laura J. P. Tan, MBBS, BSc, Christian P. Subbe, MD, Gemma Ellis, MSc, Paul Morgan, FRCA, Peter Havalda, MD, Ben Sharif, MBBCh, John Burke, MSc, Tamas Szakmany, MD, PhD, FCCM, on behalf of Welsh Digital Data Collection Platform (WDDCP) Collaborators, Maria Hobrok, Moriah Thomas, Annie Burden, Nadia Youssef, Katherine Carnegie, Helena Colling-Sylvester, Natasha Logier, Meshari Alsaeed, Hannah Williams, Arfa Ayob, Nor Farzana, Sweta Parida, David Lawson, Emily Evans, Laura Jane Davis, Billie Atkins, Llywela Wyn Davies, Lee Sanders-Crook, Steffan Treharne Seal, Alice Cains, Richard Pugh, Katy Crisp, Sarah Venning, Ella Sykes, Stephanie Narine, Georgia Parry, Emily Angela Dillon, Qi Zhuang Siah, Ting Yang, Tyler Jones, Parvathi Thara, Emma Wood, Lara Wirt, Georgina St Pier, Richard Betts, Kyriaki Mitsaki, Mari Tachweed Pierce, Sioned Davies, Yakeen Hafouda, Erin Ifan, Grace Lacey, Francesca Mitchell, John Lynch, Michal Mazur, Lezia D’Souza, Bethan Ponting, Terrance Lau, Ruairidh Kerrigan, Lucy Morgan, Roshan Vindla, Claudia Zeicu, Becky James, Amirah Amin Ariff, Wan Binti Wan Azzlan, Charlotte Collins, Elizabeth Wickens, Alisa Norbee, Aliya Zulkefli, Thomas Haddock, Megan Thomas, Matthew Lee, Miriam Cynan, Nik-Syakirah Nik Azis, Imogen Hay, Catherine Russell, Margriet Vreugdenhil, Mustafa Abdimalik, Joseph Davies, Peter Havalda, Angharad Evans, Kate Robertson, Grace Gitau, Mei-yin Gruber, Thomas Telford, Anas Qarout, Naomi Nandra, Hannah Garrard, James Cutler, Rhiannon Tammy Jones, Amy Prideaux, Timothy Spence, Sarah Hardie, Harriet Seymour, Sam Willis, Matthew Warlow, Shanali Thanthilla, Thomas Downs, Nina Foley, Chad McKeown, Akshita Dandawate, Holleh Shayan-Arani, Ellie Taylor, Oliver Kyriakides, Rachel Price, Ffion Haf Mackey, Emily Haines, Samuel Chun, Nilarnti Vignarajah, Tessa Chamberlain, Dongying Zhao, Nayanatara Nadeesha T Tantirige, Naomi Dennehey, Georgina Evans, John Watts, Ceri Battle, Ryan Jones, Selina Jones, Charlotte James, James O’Hanlon, Isabella Bridges, Bethany Hughes, Leo Polchar, Elise Bisson, Charlotte Mykura, Lara Money, Joshua McKenna, Sarah Kinsman, Demiana Hanna, Emily Baker, Harrison Sprague, Liam Sharma, Tom Pontin, Emma Shore, Tamara Hughes, Sam Nightingale, Philby Baby, Matthew Shield, Alice Cross, Jenna Boss, Olivia Ross, George Ashton, Kimaya Pandit, Daniel Davies, Cameron Garbutt, Charlotte Johnston, Marcus Cox, Chantal Roberts, Alessia Waller, Laura Heekin, Kathy Wang, Rhianna Church, Shrina Patel, Marianne Broderick, Hannah Whillis, Daniel Craig Hathaway, Emel Yildirim, Caitlin Atkins, Elin Walters, Carys Durie, Robert James Hamilton Sinnerton, Benjamin Tanner, Julimar Abreu, Kiran Bashir, Vincent Hamlyn, Amelia Tee, Zoe Ann Hinchcliffe, Rita Otto, Georgie Covell, Megan Stone, Victoria Maidman, Katherine Godfray, Rhidian Caradine, Hannah Beetham, Adanna Nicole Anomneze-Collins, Jeanette Tan, Yasmina Abdelrazik, Azizah Khan, Nabihah Malik, Aidan Clack, Lewis Oliva, Tyler Thomas, Adam George Mounce, Anoopama Ramjeeawon, Ndaba Mtunzi, Duncan Soppitt, Jay Hale, Jack Wellington, Robert Buchanan Ross, Danielle Lis, Rebecca Parsonson, Jude Joseph-Gubra, Ajitha Arunthavarajah, Jessica Nicholas, Aaron Harris, Henry Atkinson, Jessica Webster, Tim Burnett, Josephine Raffan Gowar, Sam DeFriend, Jasmine Whitaker, Elizabeth Beasant, Luis Macchiavello, Danyal Usman, Abdullah Mahdi, Tiffany Ye Tze Shan, Nick Savill, Jennifer Gee, Lizzie Hodges, Ami Desai, Hannah Rossiter, Matthew Taylor, Kevin Pinto, Eleanor Hartley, Oscar Emanuel, Rhiannon Long, Megan Selby, Elilis Wardle, Alexandra Urquhart, Jack Barrington, Matthew Ashman, Elizabeth Adcock, Amelia Dickinson, Rebecca Jordache, Rym Chafai El Alaoui, Sophie Stovold, Sam Vickery, Nia Jones, Alice O’Donnell, Monty Cuthbert, Osa Eghosa, Muhammad Karim, Lowri Williams, Louise Tucker, Tom Downs, Rebecca Walford, Annabelle Hook, Adam Mounce, Emily Eccles, Ross Edwards, Kirtika Ramesh, Charlie Hall, Maria Lazarou, Rhidian Jones, Katy McGillian, Hari Singh Bhachoo, Zoe The, Vithusha Inpahas, Ruchi Desai, Yusuf Cheema, Andrew Hughes, Olivia Cranage, Felicity Bee, Khalid Osman, Humza Khan, Jennifer Pitt, Charlotte Pickwick, Jorge Carter, Fiona Andrew, Naseera Seedat, Roshni Patel, Megan Walker, Alicia Boam, Jessica Randall, Beth Bowyer, Josh Edwards, Natasha Jones, Emma Walker, Ailsa MacNaught, Swagath Balachandran, Abbie Shipley, Jennifer Louise Kent, Samuel Tilley, Bethany Davies, Emma Withers, Krishna Parmar, Lucie Webber, Angelica Sharma, Amy Handley, Alexandra Gordon, Lucy Allen, Rebecca Paddock, Harriet Penney, Lopa Banerjee, Chloe Victoria Vanderpump, Kate Harding, John Burke, Orsolya Minik, Nia Jarrett, Ellie Rowe, Adanna Anomneze-Collins, Harry Griffiths, Sarah Pengelly, Ffion Bennett, Ahmed Bilal, Abdullah El-badawey, Bethan Ellis, Luke Cook, Harriet Elizabeth Valentine Maine, Kiri Armstrong, Hannah Beresford, Timia Raven-Gregg, Tom Liddell-Lowe, Caitlin Ong, Harriet Reed, Frederika Alice St John, Weronika Julia Kozuch, Isabelle Ray, Irukshi Anuprabha Silva, Sin Ting Natalie Cheng, Umme-Laila Ali, Noreena Syed, Luke Murphy, Thomas Grother, Harry Smith, Rachel Watson, Omar Marei, Emma Kirby, Anna Gilfedder, Lydia Maw, Sarah O’Connor, Charlotte Maden, Helena Jones, Hazel Preston, Nur Amirah Binti Maliki, Mark Zimmerman, Jessica Webber, Llewelyn Jones, Rebecca Phillips, Lauren McCarthy, Emily Hubbard, Leo Duffy, Abigail Guerrier Sadler, Tamas Szakmany, Owen Richards, Charles King, Charlotte Killick, Yusuf Chema, Kavita Shergill, Yi Huen, Lillian Lau, Hannah Mustafa Ali, Lucas Wilcock, Molly Timlin, Ayeesha Rela, Daniel Smith, Sarah Ireland, Jennifer Evans, Nayanatara Poobalan, Jessica Pearce, Thivya V Vadiveloo, Zoe Black, Daniel Elis Samuel, Humaira Hussain, Joanna Hawkins, Zeid Atiyah, Rebecca Creamer, Maham Zafar, Ahmad Almazeedi, Hannah Brunnock, Zain Nasser, Mekha Jeyanthi, Poorya Moghbel, Katie Kwan, Isobel Sutherland, Frank Davis, Abigail Rogers, Zhao Xuan Tan, Clare Chantrill, Amal Robertson, Jonathan Foulkes, Rahana Khanam, Jomcy John, Sarah Hannah Meehan, Huria Metezai, Hannah Dawson, Navrhinaa Vadivale, Camilla Lee, Amrit Dhadda, Sian Cleaver, Genna Logue, Joy Inns, Isabel Jones, Robyn Howcroft, Carys Gilbert, Matthew Bradley, Louise Pike, Rachel Keeling, Charldré Banks, Eleanor Cochrane, James McFadyen, Matthew Mo, Emily Ireland, Esme Brittain, Ihssen Laid, Charlotte Green, Adriel Mcforrester, Xuong Michelle Ly, Mariana Nalbanti, Raven Joseph, Jack Tagg, David Purchase, Pan Myat, Ayako Niina, Tyler Joshua Jones, Lowri Hughes Thomas, Natalie Hoyle, Patrick Benc, Ellen Davies, Meng-Chieh Wu, David Fellows, Sam Tilley, Eloise Baxendale, Karishma Khan, Andrew Forrester, Oliver Moore, Hse Juinn Lim, Aimee Owen, Faris Hussain, Nima-banu Allybocus, Maneha Sethi, Harry Waring, Adeel Khan, Claire Smith, Nicholas Doyle, Mohammad Yahya Amjad, Luke Galloway, Paul Morgan, Gemma Ellis, Robert Lundin, Haamed Al Hassan, Bethan Markall, Namratha Kaur, Emmanuel Onyango, Heather Beard, Elliot Field, Ellen Nelson-Rowe, Lizzie Adcock, Amelia Stoddart, Frederika St John, Mathoorika Sivananthan, Rhys Jones, Sung Yeon Kwak, Lily Farakish, Holly Rhys-Ellis, Kate Moss, Tallulah Ray, Tessa David, Talea Roberts, Annie Quy, Aniket Paranjape, Nutchanun Poolworaluk, Mary Keast, Si Liang Yao, Dion Manning, Isobel Irwin, Umair Asim, Emelia Boggon, Ibrahim Alkurd, Genevieve Lawerece, Jade Brown, Emily Murphy, Evie Lambert, Jeremy Guilford, Beth Payne, Mariam Almulaifi, Arwel Poacher, Sashiananthan Ganesananthan, Berenice Cunningham-Walker, Chloe Spooner, Akanksha Kiran, Nabeegh Nadeem, Vidhi Unadkat, Esme Sparey, David Li, Jessica Smith, India Corrin, Amit Kurani, Paul McNulty, Ceri Brown, Wojciech Groblewski, Szilvia Szoke, Amelia Redman, Esther McKeag, Anastasia Donnir, Gaautham Ravishangar, Emanuela Howard, Charlotte Salmon, Sara Tanatova, Jasmine Kew, Megan Eilis Clark, Ellen Hannay, Olesya Godsafe, Christina Houghton, Francesca Lavric, Rachel Mallinson, Chris Littler, Harsha Reddy, Andrew Campbell, Benedict Soo, Rachel Evans, Georgina Donowho, Alexandra Cawthra, Maddison Davies, Matthew Lawrence Ashman, Jamie Scriven, James Vautrey, Shannon Seet, Imogen Britton, Abigail Hodgson, Emma Twohey, Joseph Robbins, Vanessa Yeo Yung Ling, Kimiya Asjadi, Carven Chin Yee Shean, Zoe McCarroll, Oritseweyimi Amatotsero, Hei Man Priscilla Chan, John Ng Cho Hui, Antonia Ashaye, Josephine Acheampong, Ayowade Adeleye, Saber Ahmed, Alexandra Chrysostomou, Harry Unwin, Eshen Ang, Niamh McSwiney, Yin Yin Lim, Zong Xuan Lee, Svetlana Kulikouskaya, Nur Zulkifili, Sheryl Lim, Lim Xin, Adiya Urazbayeva, Nur Haslina Ahmad Hanif, Yau Ke Ying, Alice Coleclough, Eilis Higgins, Naomi Spencer, Tze Gee Ng, Sam Booth, Stephanie Wai Yee Ng, Christian P Subbe, Isabella Patterson, Wen Li Chia, Abdullah Mukit, Hei Yi Vivian Pak, Felicity Lock, Mariana Nalmpanti, Shôn Alun Thomas, Tanisha Burgher, Alfred Wei Zhen Yeo, Siwan Powell Jones, Charlie Miles, Millicent Perry, Holly Burton, Katharine Powell, Luthfun Nessa, Aalaa Fadlalla, Rhian Morgan, Elizabeth Hodges, Amelia Heal, Chloe Scott, Alice Tayler, Thomas Chandy, Abduahad Taufik, James Cochrane, Samuel Willis, Sieh Yen Heng, Alex Cooper, Henrik Graf von der Pahlen, Isabella Talbot, Robin Gwyn Roberts, Jessica Sharma Smith, Aisling Sweeney, Cerian Roberts, Laura Bausor, Chania, Daniah Thomas, Elen Wyn Puw, Ronan A Lyons, and Judith E Hall
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Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
OBJECTIVES:. To compare the performance of Sequential Organ Failure Assessment, systemic inflammatory response syndrome, Red Flag Sepsis, and National Institute of Clinical Excellence sepsis risk stratification tools in the identification of patients at greatest risk of mortality from sepsis in nonintensive care environments. DESIGN:. Secondary analysis of three annual 24-hour point-prevalence study periods. SETTING:. The general wards and emergency departments of 14 acute hospitals across Wales. Studies were conducted on the third Wednesday of October in 2017, 2018, and 2019. PATIENTS:. We screened all patients presenting to the emergency department and on the general wards. MEASUREMENTS AND MAIN RESULTS:. We recruited 1,271 patients, of which 724 (56.9%) had systemic inflammatory response syndrome greater than or equal to 2, 679 (53.4%) had Sequential Organ Failure Assessment greater than or equal to 2, and 977 (76.9%) had Red Flag Sepsis. When stratified according to National Institute of Clinical Excellence guidelines, 450 patients (35.4%) were in the “High risk” category in comparison with 665 (52.3%) in “Moderate to High risk” and 156 (12.3%) in “Low risk” category. In a planned sensitivity analysis, we found that none of the tools accurately predicted mortality at 90 days, and Sequential Organ Failure Assessment and National Institute of Clinical Excellence tools showed only moderate discriminatory power for mortality at 7 and 14 days. Furthermore, we could not find any significant correlation with any of the tools at any of the mortality time points. CONCLUSIONS:. Our data suggest that the sepsis risk stratification tools currently utilized in emergency departments and on the general wards do not predict mortality adequately. This is illustrated by the disparity in mortality risk of the populations captured by each instrument, as well as the weak concordance between them. We propose that future studies on the development of sepsis identification tools should focus on identifying predicator values of both the short- and long-term outcomes of sepsis.
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- 2021
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9. ReCodLiver0.9: Overcoming Challenges in Genome-Scale Metabolic Reconstruction of a Non-model Species
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Eileen Marie Hanna, Xiaokang Zhang, Marta Eide, Shirin Fallahi, Tomasz Furmanek, Fekadu Yadetie, Daniel Craig Zielinski, Anders Goksøyr, and Inge Jonassen
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genome-scale metabolic reconstruction ,Atlantic cod ,less-annotated species ,model curation ,environmental toxicology ,Biology (General) ,QH301-705.5 - Abstract
The availability of genome sequences, annotations, and knowledge of the biochemistry underlying metabolic transformations has led to the generation of metabolic network reconstructions for a wide range of organisms in bacteria, archaea, and eukaryotes. When modeled using mathematical representations, a reconstruction can simulate underlying genotype-phenotype relationships. Accordingly, genome-scale metabolic models (GEMs) can be used to predict the response of organisms to genetic and environmental variations. A bottom-up reconstruction procedure typically starts by generating a draft model from existing annotation data on a target organism. For model species, this part of the process can be straightforward, due to the abundant organism-specific biochemical data. However, the process becomes complicated for non-model less-annotated species. In this paper, we present a draft liver reconstruction, ReCodLiver0.9, of Atlantic cod (Gadus morhua), a non-model teleost fish, as a practicable guide for cases with comparably few resources. Although the reconstruction is considered a draft version, we show that it already has utility in elucidating metabolic response mechanisms to environmental toxicants by mapping gene expression data of exposure experiments to the resulting model.
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- 2020
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10. The effect of playing surfaces and footwear on the biomechanical response of soccer players
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Low, Daniel Craig and Dixon, Sharon J.
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612 - Abstract
This thesis describes three studies investigating biomechanical responses to changes in shoe-surface combinations in soccer. In the first study, six male participants (21.7 [S.D. 2.2] yrs, 74.0 [S.D. 6.9] kg [March], 74.6 [S.D. 6.9] kg (May), footwear size 10 -11) performed running and turning movements on natural and third generation artificial surfaces whilst wearing different soccer specific footwear. This was performed at two times of the year where contrasting weather conditions were experienced. It was observed that there were significant differences when the natural and third generation artificial turf surfaces were compared. These differences however, were dependent on the type of movement, time of year and biomechanical measurement used. Each surface was also compared between the two test occasions. The main finding was that for both running and turning peak pressures and peak pressure loading rates were significantly greater in May (when the surfaces were mechanically hard) compared with the same surface in March. It was concluded that comparisons of third generation surfaces with natural turf are dependent on the specific properties of the surfaces and cannot be generalized for all such surfaces. A critical design feature of third generation surfaces that will influence biomechanical comparisons with other playing surfaces is the shock pad layer. In the second experimental chapter, ten male participants (20.9 yrs [S.D. 2.5], 83.2 kg [S.D. 7.1], footwear size 10 -11) were used to assess the effect of two different shock pad densities (55g and 65g) (Arpro® Expanded polypropylene BF2455W, 24mm S.D. 0.5mm thick, Brock International) on the lower extremity loading. These participants were also used to assess the biomechanical adaptations that occur with the inclusion of a 10 mm Sorbothane® heel insert or a Sorbothane® cushioning insole (Sorbo products division, Lancashire, UK), which have been associated with reducing overuse injury including that to the Achilles tendon. The footwear was also assessed for the risk of sustaining lateral ankle ligament damage. It was shown that whilst turning, peak impact force (taken using in-shoe pressure system) was significantly lower on the more cushioned shock pad as was peak pressure at the first metatarsal. Likewise, the time to peak impact force was significantly longer with the heel insert. However, despite the association between the heel insert and reduced dorsi-flexion, no significant differences were observed for this measurement between the footwear conditions. Peak plantar flexion was significantly greater with the heel insert whilst turning suggesting an increased loading of the lateral ankle ligaments, although rearfoot inversion was not significantly different. This study demonstrated the potential role of shock pad cushioning in providing protection from impact related injury in soccer, whilst cushioning inserts were not found to provide a protective effect. For heel inserts, the possibility of a negative influence on rearfoot stability was highlighted. It was suggested that the estimation of internal loads may reveal more regarding the specific role of cushioning interfaces and heel inserts in protecting from injury. In the final research chapter, nine male soccer players (83.4 kg [S.D. 5.8], 23 yrs [S.D. 3.7]) performed running and turning movements for the same conditions described in study two. The peak plantar flexion moment, Achilles tendon force and average loading rate of these measurements, were used to assess Achilles tendon loading. Likewise, peak dorsi-flexion and eversion moments were collected to assess the lateral ankle loading. Group analysis did not reveal any significant differences in these variables. Individual data showed that the response to heel insert intervention was specific to the participant. Some participants exhibited a reduced Achilles tendon force or average loading rate, suggesting a reduced risk of injury with the heel insert. However, it was observed that eversion and dorsi-flexion moment and average loading rates increased in some participants, suggesting that these participants were at an increased risk of lateral ankle ligament injury with the heel insert. Likewise, one participant experienced significantly greater peak Achilles tendon force, also indicating a greater risk of injury to this structure. The overall conclusions gained from these studies are that the design of the footwear and playing surfaces are worth considering in the quest to reduce injury risk. It was also highlighted that the choice of shock pad density for a third generation artificial surface can be influential in the protection of the athlete even when the surface is new, particularly when turning. Finally, although the use of heel inserts has proven successful in the reduction the Achilles tendon injury, the lack of significant differences for group comparisons suggests that the mechanisms behind the success is still unclear. However, although heel inserts may prove useful in the reduction of Achilles tendon injury, the observation that significant increases in the measurements associated with acute ankle ligament damage and chronic Achilles tendon injury, suggests that heel lift may not be suitable for some individuals.
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- 2010
11. Description of sound absorption by a flat resonator stacking metamaterial with double porosity model
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Brooke, Daniel Craig, primary, Umnova, Olga, additional, Leclaire, Philippe, additional, and Dupont, Thomas, additional
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- 2023
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12. Changing Tides: Screening for Social Determinants of Health in Asian American and Native Hawaiian/Pacific Islander Communities
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Michael Zhao, Michael Zhao, Matt Polari, Daniel Craig, Pingjing Zou, Felicitas Aquegho, Joanna Lu, Joshua Samos, David Li, Michael Zhao, Michael Zhao, Matt Polari, Daniel Craig, Pingjing Zou, Felicitas Aquegho, Joanna Lu, Joshua Samos, and David Li
- Abstract
Change InSight is an information clearinghouse for the nation's Asian American, Native Hawaiian, and Pacific Islander (AA and NHPI) communities as well as other underrepresented communities (e.g. immigrant communities, communities of color, racial minority groups, vulnerable populations, etc.). Change InSight leverages data to understand minority communities at a deeper level, empowering these communities by:Identifying and addressing the social risks and needs unique to AA and NHPI populations through targeted data collection infrastructure;Challenging misconceptions about the AA and NHPI populations using the collected data;Increase awareness of the shortfall in foundation funding for AA and NHPI organizations relative to these communities' population size and growth; andInforming decision-making at a broader scale through data-backed policy insights.This report shows how Change InSight is working to eliminate health and funding disparities for AA and NHPI communities. For far too long, the AA and NHPI communities have been categorized as a single entity (i.e. "Asians" or "Asian Americans"), leading to a critical lack of culturally-responsive interventions, solutions, and resources. To understand what these communities need, it's important to consider how environmental and personal conditions impact health outcomes. These conditions are known as social determinants of health (SDOH/SDH)2.From April 1st to June 24th, 2022, Change InSight partner agencies collected social determinants of health data from 2,244 AA and NHPI individuals. Findings from this sample were then compared with public narratives from multiple sources and supplemented by anecdotal evidence from all involved stakeholders. This new research initiative offers policymakers, nonprofit leaders, community health workers, philanthropic organizations, and civic centers a better understanding of their clients and constituents. This report is a product of a year-long collaboration by nonprofit leaders, pro
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- 2023
13. The Expanding Computational Toolbox for Engineering Microbial Phenotypes at the Genome Scale
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Daniel Craig Zielinski, Arjun Patel, and Bernhard O. Palsson
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synthetic biology ,metabolic modeling ,machine learning ,metabolic engineering ,Biology (General) ,QH301-705.5 - Abstract
Microbial strains are being engineered for an increasingly diverse array of applications, from chemical production to human health. While traditional engineering disciplines are driven by predictive design tools, these tools have been difficult to build for biological design due to the complexity of biological systems and many unknowns of their quantitative behavior. However, due to many recent advances, the gap between design in biology and other engineering fields is closing. In this work, we discuss promising areas of development of computational tools for engineering microbial strains. We define five frontiers of active research: (1) Constraint-based modeling and metabolic network reconstruction, (2) Kinetics and thermodynamic modeling, (3) Protein structure analysis, (4) Genome sequence analysis, and (5) Regulatory network analysis. Experimental and machine learning drivers have enabled these methods to improve by leaps and bounds in both scope and accuracy. Modern strain design projects will require these tools to be comprehensively applied to the entire cell and efficiently integrated within a single workflow. We expect that these frontiers, enabled by the ongoing revolution of big data science, will drive forward more advanced and powerful strain engineering strategies.
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- 2020
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14. Severe Aortic Stenosis in Patients With Chronic Liver Disease: A Comprehensive Review
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Daniel Craig, Addison J. Bond, Latifah Ahmad, Morgan Stanley, Addis Asfaw, Samuel B. Latham, and Uzoma N. Ibebuogu
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General Medicine ,Cardiology and Cardiovascular Medicine - Published
- 2023
15. A Peptide-Fc Opsonin with Pan-Amyloid Reactivity
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James S. Foster, Angela D. Williams, Sallie Macy, Tina Richey, Alan Stuckey, Daniel Craig Wooliver, Richa Koul-Tiwari, Emily B. Martin, Stephen J. Kennel, and Jonathan S. Wall
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Fc-fusion ,peptide p5 ,amyloidosis ,AA amyloid ,phagocytosis ,Immunologic diseases. Allergy ,RC581-607 - Abstract
There is a continuing need for therapeutic interventions for patients with the protein misfolding disorders that result in systemic amyloidosis. Recently, specific antibodies have been employed to treat AL amyloidosis by opsonizing tissue amyloid deposits thereby inducing cell-mediated dissolution and organ improvement. To develop a pan-amyloid therapeutic agent, we have produced an Fc-fusion product incorporating a peptide, p5, which binds many if not all forms of amyloid. This protein, designated Fcp5, expressed in mammalian cells, forms the desired bivalent dimer structure and retains pan-amyloid reactivity similar to the p5 peptide as measured by immunosorbent assays, immunohistochemistry, surface plasmon resonance, and pulldown assays using radioiodinated Fcp5. Additionally, Fcp5 was capable of opsonizing amyloid fibrils in vitro using a pH-sensitive fluorescence assay of phagocytosis. In mice,125 I-labeled Fcp5 exhibited an extended serum circulation time, relative to the p5 peptide. It specifically bound AA amyloid deposits in diseased mice, as evidenced by biodistribution and microautoradiographic methods, which coincided with an increase in active, Iba-1-positive macrophages in the liver at 48 h postinjection of Fcp5. In healthy mice, no specific tissue accumulation was observed. The data indicate that polybasic, pan-amyloid-targeting peptides, in the context of an Fc fusion, can yield amyloid reactive, opsonizing reagents that may serve as next-generation immunotherapeutics.
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- 2017
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16. The minimal important change for measures of balance and postural control in older adults: a systematic review
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Daniel Craig Low and Gregory Walsh
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Aging ,Humans ,Reproducibility of Results ,General Medicine ,Geriatrics and Gerontology ,Postural Balance ,Physical Therapy Modalities ,Aged - Abstract
Supplementary data: aa-22-1228-File002_afac284 - docx file available online at https://academic.oup.com/ageing/article/51/12/afac284/6931845?login=false#supplementary-data Copyright © The Author(s) 2022. The minimal important change and analogous terms (MIC) can provide a measure of change in health outcome variables that is associated with a level of importance for participant/patient. This review explores the availability of the MIC for different balance measures used with older adults in research and clinical settings. PubMed, ProQuest and Web of Science search engines were used and based on the inclusion and exclusion criteria, 11 studies were deemed suitable for data extraction and analysis. The results demonstrated that MIC is available for the following balance-associated tests: Berg Balance Scale, Timed Up and Go, Short Physical Performance Battery, BESTest and the Tinetti test. A range of MIC values were shown, reflective of different older adult health conditions, calculation methods and anchors used. It was also evident that the responsiveness of the test was not always available or appropriately determined, questioning the validity of the MIC value published. Greater research is needed to establish MIC for balance measurements for use with older adults with different health conditions, preferably using objective measures such as falls. The calculation of such statistics will improve the evaluation of intervention effectiveness.
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- 2022
17. PULSE TRAINS: THE RARE ECG FINDINGS IN DILATED CARDIOMYOPATHIES
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Dusty Trotman, Aranyak Rawal, James Elliott, Cassidy Lounsbury, Daniel Craig, Frank A. McGrew, and John L. Jefferies
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Cardiology and Cardiovascular Medicine - Published
- 2023
18. Recommendations for effective documentation in regional anesthesia: an expert panel Delphi consensus project
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Ahmed, Hassan M, Atterton, Benjamin P, Crowe, Gillian G, Barratta, Jaime L, Johnson, Mark, Viscusi, Eugene R., Adhikary, Sanjib, Albrecht, Eric, Boretsky, Karen, Boublik, Jan, Breslin, Dara S, Byrne, Kelly, Ch'ng, Alan, Chuan, Alwin, Conroy, Patrick, Daniel, Craig, Daszkiewicz, Andrzej, Delbos, Alain, Dirzu, Dan Sebastian, Dmytriiev, Dmytro, Fennessy, Paul, Fischer, H Barrie J, Frizelle, Henry, Gadsden, Jeff, Gautier, Philippe, Gupta, Rajnish K, Gürkan, Yavuz, Hardman, Harold David, Harrop-Griffiths, William, Hebbard, Peter, Hernandez, Nadia, Hlasny, Jakub, Iohom, Gabriella, Ip, Vivian H Y, Jeng, Christina L, Johnson, Rebecca L, Kalagara, Hari, Kinirons, Brian, Lansdown, Andrew Kenneth, Leng, Jody C, Lim, Yean Chin, Lobo, Clara, Ludwin, Danielle B, Macfarlane, Alan James Robert, Machi, Anthony T, Mahon, Padraig, Mannion, Stephen, McLeod, David H, Merjavy, Peter, Miscuks, Aleksejs, Mitchell, Christopher H, Moka, Eleni, Moran, Peter, Ngui, Ann, Nin, Olga C, O'Donnell, Brian D, Pawa, Amit, Perlas, Anahi, Porter, Steven, Pozek, John-Paul, Rebelo, Humberto C, Roqués, Vicente, Schroeder, Kristopher M, Schwartz, Gary, Schwenk, Eric S., Sermeus, Luc, Shorten, George, Srinivasan, Karthikeyan, Stevens, Markus F, Theodoraki, Kassiani, Turbitt, Lloyd R, Valdés-Vilches, Luis Fernando, Volk, Thomas, Webster, Katrina, Wiesmann, T, Wilson, Sylvia H, Wolmarans, Morné, Woodworth, Glenn, Worek, Andrew K, Moran, E M Louise, Ahmed, Hassan M, Atterton, Benjamin P, Crowe, Gillian G, Barratta, Jaime L, Johnson, Mark, Viscusi, Eugene R., Adhikary, Sanjib, Albrecht, Eric, Boretsky, Karen, Boublik, Jan, Breslin, Dara S, Byrne, Kelly, Ch'ng, Alan, Chuan, Alwin, Conroy, Patrick, Daniel, Craig, Daszkiewicz, Andrzej, Delbos, Alain, Dirzu, Dan Sebastian, Dmytriiev, Dmytro, Fennessy, Paul, Fischer, H Barrie J, Frizelle, Henry, Gadsden, Jeff, Gautier, Philippe, Gupta, Rajnish K, Gürkan, Yavuz, Hardman, Harold David, Harrop-Griffiths, William, Hebbard, Peter, Hernandez, Nadia, Hlasny, Jakub, Iohom, Gabriella, Ip, Vivian H Y, Jeng, Christina L, Johnson, Rebecca L, Kalagara, Hari, Kinirons, Brian, Lansdown, Andrew Kenneth, Leng, Jody C, Lim, Yean Chin, Lobo, Clara, Ludwin, Danielle B, Macfarlane, Alan James Robert, Machi, Anthony T, Mahon, Padraig, Mannion, Stephen, McLeod, David H, Merjavy, Peter, Miscuks, Aleksejs, Mitchell, Christopher H, Moka, Eleni, Moran, Peter, Ngui, Ann, Nin, Olga C, O'Donnell, Brian D, Pawa, Amit, Perlas, Anahi, Porter, Steven, Pozek, John-Paul, Rebelo, Humberto C, Roqués, Vicente, Schroeder, Kristopher M, Schwartz, Gary, Schwenk, Eric S., Sermeus, Luc, Shorten, George, Srinivasan, Karthikeyan, Stevens, Markus F, Theodoraki, Kassiani, Turbitt, Lloyd R, Valdés-Vilches, Luis Fernando, Volk, Thomas, Webster, Katrina, Wiesmann, T, Wilson, Sylvia H, Wolmarans, Morné, Woodworth, Glenn, Worek, Andrew K, and Moran, E M Louise
- Abstract
Background and objectives: Documentation is important for quality improvement, education, and research. There is currently a lack of recommendations regarding key aspects of documentation in regional anesthesia. The aim of this study was to establish recommendations for documentation in regional anesthesia. Methods: Following the formation of the executive committee and a directed literature review, a long list of potential documentation components was created. A modified Delphi process was then employed to achieve consensus amongst a group of international experts in regional anesthesia. This consisted of 2 rounds of anonymous electronic voting and a final virtual round table discussion with live polling on items not yet excluded or accepted from previous rounds. Progression or exclusion of potential components through the rounds was based on the achievement of strong consensus. Strong consensus was defined as ≥75% agreement and weak consensus as 50%-74% agreement. Results: Seventy-seven collaborators participated in both rounds 1 and 2, while 50 collaborators took part in round 3. In total, experts voted on 83 items and achieved a strong consensus on 51 items, weak consensus on 3 and rejected 29. Conclusion: By means of a modified Delphi process, we have established expert consensus on documentation in regional anesthesia.
- Published
- 2022
19. Recommendations for effective documentation in regional anesthesia: an expert panel Delphi consensus project.
- Author
-
UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service d'anesthésiologie, Ahmed, Hassan M, Atterton, Benjamin P, Crowe, Gillian G, Barratta, Jaime L, Johnson, Mark, Viscusi, Eugene, Adhikary, Sanjib, Albrecht, Eric, Boretsky, Karen, Boublik, Jan, Breslin, Dara S, Byrne, Kelly, Ch'ng, Alan, Chuan, Alwin, Conroy, Patrick, Daniel, Craig, Daszkiewicz, Andrzej, Delbos, Alain, Dirzu, Dan Sebastian, Dmytriiev, Dmytro, Fennessy, Paul, Fischer, H Barrie J, Frizelle, Henry, Gadsden, Jeff, Gautier, Philippe, Gupta, Rajnish K, Gürkan, Yavuz, Hardman, Harold David, Harrop-Griffiths, William, Hebbard, Peter, Hernandez, Nadia, Hlasny, Jakub, Iohom, Gabriella, Ip, Vivian H Y, Jeng, Christina L, Johnson, Rebecca L, Kalagara, Hari, Kinirons, Brian, Lansdown, Andrew Kenneth, Leng, Jody C, Lim, Yean Chin, Lobo, Clara, Ludwin, Danielle B, Macfarlane, Alan James Robert, Machi, Anthony T, Mahon, Padraig, Mannion, Stephen, McLeod, David H, Merjavy, Peter, Miscuks, Aleksejs, Mitchell, Christopher H, Moka, Eleni, Moran, Peter, Ngui, Ann, Nin, Olga C, O'Donnell, Brian D, Pawa, Amit, Perlas, Anahi, Porter, Steven, Pozek, John-Paul, Rebelo, Humberto C, Roqués, Vicente, Schroeder, Kristopher M, Schwartz, Gary, Schwenk, Eric S, Sermeus, Luc, Shorten, George, Srinivasan, Karthikeyan, Stevens, Markus F, Theodoraki, Kassiani, Turbitt, Lloyd R, Valdés-Vilches, Luis Fernando, Volk, Thomas, Webster, Katrina, Wiesmann, T, Wilson, Sylvia H, Wolmarans, Morné, Woodworth, Glenn, Worek, Andrew K, Moran, E M Louise, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service d'anesthésiologie, Ahmed, Hassan M, Atterton, Benjamin P, Crowe, Gillian G, Barratta, Jaime L, Johnson, Mark, Viscusi, Eugene, Adhikary, Sanjib, Albrecht, Eric, Boretsky, Karen, Boublik, Jan, Breslin, Dara S, Byrne, Kelly, Ch'ng, Alan, Chuan, Alwin, Conroy, Patrick, Daniel, Craig, Daszkiewicz, Andrzej, Delbos, Alain, Dirzu, Dan Sebastian, Dmytriiev, Dmytro, Fennessy, Paul, Fischer, H Barrie J, Frizelle, Henry, Gadsden, Jeff, Gautier, Philippe, Gupta, Rajnish K, Gürkan, Yavuz, Hardman, Harold David, Harrop-Griffiths, William, Hebbard, Peter, Hernandez, Nadia, Hlasny, Jakub, Iohom, Gabriella, Ip, Vivian H Y, Jeng, Christina L, Johnson, Rebecca L, Kalagara, Hari, Kinirons, Brian, Lansdown, Andrew Kenneth, Leng, Jody C, Lim, Yean Chin, Lobo, Clara, Ludwin, Danielle B, Macfarlane, Alan James Robert, Machi, Anthony T, Mahon, Padraig, Mannion, Stephen, McLeod, David H, Merjavy, Peter, Miscuks, Aleksejs, Mitchell, Christopher H, Moka, Eleni, Moran, Peter, Ngui, Ann, Nin, Olga C, O'Donnell, Brian D, Pawa, Amit, Perlas, Anahi, Porter, Steven, Pozek, John-Paul, Rebelo, Humberto C, Roqués, Vicente, Schroeder, Kristopher M, Schwartz, Gary, Schwenk, Eric S, Sermeus, Luc, Shorten, George, Srinivasan, Karthikeyan, Stevens, Markus F, Theodoraki, Kassiani, Turbitt, Lloyd R, Valdés-Vilches, Luis Fernando, Volk, Thomas, Webster, Katrina, Wiesmann, T, Wilson, Sylvia H, Wolmarans, Morné, Woodworth, Glenn, Worek, Andrew K, and Moran, E M Louise
- Abstract
Documentation is important for quality improvement, education, and research. There is currently a lack of recommendations regarding key aspects of documentation in regional anesthesia. The aim of this study was to establish recommendations for documentation in regional anesthesia. Following the formation of the executive committee and a directed literature review, a long list of potential documentation components was created. A modified Delphi process was then employed to achieve consensus amongst a group of international experts in regional anesthesia. This consisted of 2 rounds of anonymous electronic voting and a final virtual round table discussion with live polling on items not yet excluded or accepted from previous rounds. Progression or exclusion of potential components through the rounds was based on the achievement of strong consensus. Strong consensus was defined as ≥75% agreement and weak consensus as 50%-74% agreement. Seventy-seven collaborators participated in both rounds 1 and 2, while 50 collaborators took part in round 3. In total, experts voted on 83 items and achieved a strong consensus on 51 items, weak consensus on 3 and rejected 29. By means of a modified Delphi process, we have established expert consensus on documentation in regional anesthesia.
- Published
- 2022
20. Recommendations for effective documentation in regional anesthesia: an expert panel Delphi consensus project
- Author
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Gürkan, Yavuz (ORCID 0000-0002-2307-6943 & YÖK ID 154129), Ahmed, Hassan M.; Atterton, Benjamin P.; Crowe, Gillian G.; Barratta, Jaime L.; Johnson, Mark; Viscusi, Eugene; Adhikary, Sanjib; Albrecht, Eric; Boretsky, Karen; Boublik, Jan; Breslin, Dara S.; Byrne, Kelly; Ch'ng, Alan; Chuan, Alwin; Conroy, Patrick; Daniel, Craig; Daszkiewicz, Andrzej; Delbos, Alain; Dirzu, Dan Sebastian; Dmytriiev, Dmytro; Fennessy, Paul; Fischer, H. Barrie J.; Frizelle, Henry; Gadsden, Jeff; Gautier, Philippe; Gupta, Rajnish K.; Hardman, Harold David; Harrop-Griffiths, William; Hebbard, Peter; Hernandez, Nadia; Hlasny, Jakub; Iohom, Gabriella; Ip, Vivian H. Y.; Jeng, Christina L. .; Johnson, Rebecca L.; Kalagara, Hari; Kinirons, Brian; Lansdown, Andrew Kenneth; Leng, Jody C.; Lim, Yean Chin; Lobo, Clara; Ludwin, Danielle B.; Macfarlane, Alan James Robert; Machi, Anthony T.; Mahon, Padraig; Mannion, Stephen; McLeod, David H.; Merjavy, Peter; Miscuks, Aleksejs; Mitchell, Christopher H.; Moka, Eleni; Moran, Peter; Ngui, Ann; Nin, Olga C.; O'Donnell, Brian D.; Pawa, Amit; Perlas, Anahi; Porter, Steven; Pozek, John-Paul; Rebelo, Humberto C.; Roques, Vicente; Schroeder, Kristopher M.; Schwartz, Gary; Schwenk, Eric S.; Sermeus, Luc; Shorten, George; Srinivasan, Karthikeyan; Stevens, Markus F.; Theodoraki, Kassiani; Turbitt, Lloyd R.; Valdes-Vilches, Luis Fernando; Volk, Thomas; Webster, Katrina; Wiesmann, T.; Wilson, Sylvia H.; Wolmarans, Morne; Woodworth, Glenn; Worek, Andrew K.; Moran, E. M. Louise, Koç University Hospital, School of Medicine, Gürkan, Yavuz (ORCID 0000-0002-2307-6943 & YÖK ID 154129), Ahmed, Hassan M.; Atterton, Benjamin P.; Crowe, Gillian G.; Barratta, Jaime L.; Johnson, Mark; Viscusi, Eugene; Adhikary, Sanjib; Albrecht, Eric; Boretsky, Karen; Boublik, Jan; Breslin, Dara S.; Byrne, Kelly; Ch'ng, Alan; Chuan, Alwin; Conroy, Patrick; Daniel, Craig; Daszkiewicz, Andrzej; Delbos, Alain; Dirzu, Dan Sebastian; Dmytriiev, Dmytro; Fennessy, Paul; Fischer, H. Barrie J.; Frizelle, Henry; Gadsden, Jeff; Gautier, Philippe; Gupta, Rajnish K.; Hardman, Harold David; Harrop-Griffiths, William; Hebbard, Peter; Hernandez, Nadia; Hlasny, Jakub; Iohom, Gabriella; Ip, Vivian H. Y.; Jeng, Christina L. .; Johnson, Rebecca L.; Kalagara, Hari; Kinirons, Brian; Lansdown, Andrew Kenneth; Leng, Jody C.; Lim, Yean Chin; Lobo, Clara; Ludwin, Danielle B.; Macfarlane, Alan James Robert; Machi, Anthony T.; Mahon, Padraig; Mannion, Stephen; McLeod, David H.; Merjavy, Peter; Miscuks, Aleksejs; Mitchell, Christopher H.; Moka, Eleni; Moran, Peter; Ngui, Ann; Nin, Olga C.; O'Donnell, Brian D.; Pawa, Amit; Perlas, Anahi; Porter, Steven; Pozek, John-Paul; Rebelo, Humberto C.; Roques, Vicente; Schroeder, Kristopher M.; Schwartz, Gary; Schwenk, Eric S.; Sermeus, Luc; Shorten, George; Srinivasan, Karthikeyan; Stevens, Markus F.; Theodoraki, Kassiani; Turbitt, Lloyd R.; Valdes-Vilches, Luis Fernando; Volk, Thomas; Webster, Katrina; Wiesmann, T.; Wilson, Sylvia H.; Wolmarans, Morne; Woodworth, Glenn; Worek, Andrew K.; Moran, E. M. Louise, Koç University Hospital, and School of Medicine
- Abstract
Background and objectives: documentation is important for quality improvement, education, and research. There is currently a lack of recommendations regarding key aspects of documentation in regional anesthesia. The aim of this study was to establish recommendations for documentation in regional anesthesia. Methods: following the formation of the executive committee and a directed literature review, a long list of potential documentation components was created. A modified Delphi process was then employed to achieve consensus amongst a group of international experts in regional anesthesia. This consisted of 2 rounds of anonymous electronic voting and a final virtual round table discussion with live polling on items not yet excluded or accepted from previous rounds. Progression or exclusion of potential components through the rounds was based on the achievement of strong consensus. Strong consensus was defined as >= 75% agreement and weak consensus as 50%-74% agreement. Results: seventy-seven collaborators participated in both rounds 1 and 2, while 50 collaborators took part in round 3. In total, experts voted on 83 items and achieved a strong consensus on 51 items, weak consensus on 3 and rejected 29. Conclusion: by means of a modified Delphi process, we have established expert consensus on documentation in regional anesthesia., European Society of Regional Anaesthesia and Pain Therapy (ESRA); ASRA Pain Medicine
- Published
- 2022
21. Effects of static stretching following a dynamic warm-up on speed, agility and power
- Author
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Daniel Craig Bishop and Geoff Middleton
- Subjects
Performance enhancement ,Warm-Up ,Vertical jump ,20m sprint ,Illinois agility ,Sports medicine ,RC1200-1245 - Abstract
Bishop D, Middleton G. Effects of static stretching following a dynamic warm-up on speed, agility and power. J. Hum. Sport Exerc. Vol.8, No. 2, pp. 391-400, 2013. Static stretching prior to sport has been shown to decrease force production in comparison to the increasing popularity of dynamic warm-up methods. However some athletes continue to use a bout of static stretching following dynamic methods. The purpose of this study was to investigate the effects on speed, agility and power following a period of additional static stretching following a dynamic warm-up routine. Twenty-five male University students who participated in team sports performed two warm-up protocols concentrating on the lower body one week apart through a randomised cross over design. The dynamic warm-up (DW) protocol used a series of specific progressive exercises lasting 10 minutes over a distance of 20m. The dynamic warm-up plus static stretching (DWS) protocol used the same DW protocol followed by a 5 minute period during which 7 muscle groups were stretched. Following each warm-up the subjects performed a countermovement vertical jump, 20m sprint and Illinois agility test, 1 minute apart. The results demonstrated no significant differences in speed, agility and jump performance following the two protocols DW and DWS. The study concludes that performing static stretching following a dynamic warm-up prior to performance does not significantly affect speed, agility and vertical jump performance.
- Published
- 2013
- Full Text
- View/download PDF
22. Recommendations for effective documentation in regional anesthesia: an expert panel Delphi consensus project
- Author
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Ahmed, Hassan M, primary, Atterton, Benjamin P, additional, Crowe, Gillian G, additional, Barratta, Jaime L, additional, Johnson, Mark, additional, Viscusi, Eugene, additional, Adhikary, Sanjib, additional, Albrecht, Eric, additional, Boretsky, Karen, additional, Boublik, Jan, additional, Breslin, Dara S, additional, Byrne, Kelly, additional, Ch'ng, Alan, additional, Chuan, Alwin, additional, Conroy, Patrick, additional, Daniel, Craig, additional, Daszkiewicz, Andrzej, additional, Delbos, Alain, additional, Dirzu, Dan Sebastian, additional, Dmytriiev, Dmytro, additional, Fennessy, Paul, additional, Fischer, H Barrie J, additional, Frizelle, Henry, additional, Gadsden, Jeff, additional, Gautier, Philippe, additional, Gupta, Rajnish K, additional, Gürkan, Yavuz, additional, Hardman, Harold David, additional, Harrop-Griffiths, William, additional, Hebbard, Peter, additional, Hernandez, Nadia, additional, Hlasny, Jakub, additional, Iohom, Gabriella, additional, Ip, Vivian H Y, additional, Jeng, Christina L, additional, Johnson, Rebecca L, additional, Kalagara, Hari, additional, Kinirons, Brian, additional, Lansdown, Andrew Kenneth, additional, Leng, Jody C, additional, Lim, Yean Chin, additional, Lobo, Clara, additional, Ludwin, Danielle B, additional, Macfarlane, Alan James Robert, additional, Machi, Anthony T, additional, Mahon, Padraig, additional, Mannion, Stephen, additional, McLeod, David H, additional, Merjavy, Peter, additional, Miscuks, Aleksejs, additional, Mitchell, Christopher H, additional, Moka, Eleni, additional, Moran, Peter, additional, Ngui, Ann, additional, Nin, Olga C, additional, O'Donnell, Brian D, additional, Pawa, Amit, additional, Perlas, Anahi, additional, Porter, Steven, additional, Pozek, John-Paul, additional, Rebelo, Humberto C, additional, Roqués, Vicente, additional, Schroeder, Kristopher M, additional, Schwartz, Gary, additional, Schwenk, Eric S, additional, Sermeus, Luc, additional, Shorten, George, additional, Srinivasan, Karthikeyan, additional, Stevens, Markus F, additional, Theodoraki, Kassiani, additional, Turbitt, Lloyd R, additional, Valdés-Vilches, Luis Fernando, additional, Volk, Thomas, additional, Webster, Katrina, additional, Wiesmann, T, additional, Wilson, Sylvia H, additional, Wolmarans, Morné, additional, Woodworth, Glenn, additional, Worek, Andrew K, additional, and Moran, E M Louise, additional
- Published
- 2022
- Full Text
- View/download PDF
23. Description of sound absorption by a flat resonator stacking metamaterial with double porosity model
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Daniel Craig Brooke, Olga Umnova, Philippe Leclaire, Thomas Dupont, and drive, drive
- Subjects
[SPI] Engineering Sciences [physics] - Abstract
Acoustic metamaterials can be designed by inserting along the path of a sound wave periodically spaced side resonators. An example of efficient design was recently proposed consisting of a perforated stacking of flat annular cavities (the pancake resonator), the perforation allowing the propagation of sound waves. The pancake resonator is used in absorber mode and the theoretical description of sound absorption can be achieved with the help of the theory of sound propagation in fluid saturated porous media in which two porosities are considered: the main porosity associated with the perforation and a porosity associated with the flat cavity volumes. Considering a perforation diameter and flat cavity thickness ranging from submillimetric values to a few millimeters allows a wide range of material permeabilities and permeability contrasts between main pore and stacking of cavities. The relatively small values of diameter and cavity thickness also results in the existence of viscous and thermal boundary layers in the main pore (the perforation) and in the flat cavities. This metamaterial makes simultaneous use of viscothermal losses and periodicity in order to achieve low frequency sound absorption for an overall small absorber thickness. Experimental results are also presented for the validation of the model.
- Published
- 2022
24. Resetting the theater to equip rotational forces in Europe: European activity set equipment provides regionally aligned forces with the tools needed to perform a complex mission in a changing operational environment
- Author
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Daniel, Craig A. and Dothager, Robin T.
- Subjects
United States. Army. Europe -- Reorganization and restructuring -- Foreign operations ,Military maneuvers -- Service enhancement -- Strategic aspects ,Company organization ,Company restructuring/company reorganization ,General interest ,Military and naval science - Abstract
When U.S. Army Europe's (USAREUR's) size peaked after the Cold War, it contained two corps headquarters, more than six divisions, two armored cavalry regiments, various enabling units, more than 277,000 [...]
- Published
- 2016
25. Balancing sustainment priorities for a new security paradigm in Europe
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Gamble, Duane A., Redding, Matthew D., and Daniel, Craig A.
- Subjects
United States. Army -- Safety and security measures ,Military personnel -- Military aspects ,General interest ,Military and naval science - Abstract
In the future European theater of operations, sustainment formations will need to operate in a secure network, under a missile defense shield and have sufficient and dispersed stocks of ammunition, [...]
- Published
- 2016
26. Using metabolic network reconstructions to analyze complex data sets
- Author
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Zielinski, Daniel Craig
- Subjects
UCSD Dissertations, Academic Bioengineering (Discipline) - Abstract
Understanding the behavior of complex biochemical networks is the primary goal of systems biology. This task is often addressed through the generation of large data sets such as measurements of biological components like mRNA transcripts, proteins, and metabolites. Although these methods have become increasingly accurate and comprehensive at measuring the state of the system, uncovering the function of the system then becomes a problem of analysis to extract an understanding of the system from the data. A key challenge in analyzing biological data sets is that determining the function of the system depends on a knowledge of the relationship between the components of the system. These relationships can be captured by grouping variables by known associations, such as pathways, or by explicitly modeling their relationships mathematically. Metabolic networks are particularly primed for both of these approaches, because metabolic pathways are well-defined by network topology and the equation governing their function, the mass balance equation, is well understood. In this thesis, the capabilities of metabolic networks to interpret biological data are advanced through the development and application of models of increasing levels of detail. First, pathways systematically derived from a global human metabolic network reconstruction are used to identify metabolic perturbations tied to drug side effects from in vitro drug -treated gene expression data. Second, steady-state flux modeling of a core human metabolic network is used to identify factors underlying two hallmarks of cancer metabolism: the Warburg effect and glutamine addiction. Finally, the concept of a metabolic network reconstruction is extended by the definition of detailed enzyme kinetic mechanisms within E. coli central metabolism, integrating multiple data sets mechanistically to calculate dynamic functional states of enzymes. This work furthers the use of metabolic networks in analyzing complex biological data sets, showcasing the utility of these networks in addressing practical questions in systems biology using methods of increasing mechanistic resolution
- Published
- 2015
27. Health promotion needs and challenges
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Daniel Craig, Merryn McKinnon, and Andrea Waling
- Subjects
Health promotion ,business.industry ,Public relations ,Psychology ,business - Published
- 2021
28. Saving the Church of England: John Edwards (1637-1716) as dissenting conformer
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Norman, Daniel Craig
- Abstract
Following early retirement from parish work, Edwards undertook a mission to defend and preserve the Church of England. Against those who sought to make optional those doctrines traditionally considered as essential for Christian orthodoxy, such as the Trinity and Incarnation, Edwards was uncompromising. Removing foundational ordinances of Christianity would destroy the church. To counter Arian and Socinian threats, Edwards entered the pamphlet wars, engaging some of the leading heterodox intellectuals of his day, including John Locke, Samuel Clarke, and William Whiston.\ud \ud Edwards was also committed to church unity for those who accepted as essential those doctrines delineated in the Apostles’, Nicene and Athanasian Creeds upon which the XXXIX Articles were based. Though a committed Calvinist, he willingly subordinated his theological preferences on non-essentials to greater principle of unity by respectfully remaining in the church dominated by Latitudinarians and others who did not share his Reformed theology.\ud \ud Leaders on all sides of the seventeenth-century dissension paid lip service to church unity, but failed to act on it. Edwards practiced genuine toleration within the traditional bounds of orthodoxy but he would not extend his tolerance to define the church out of existence. Toleration, after all, is a weak version of Christian love and it was clear to Edwards that lack of love was the basis for division.\ud \ud Most contemporary references to John Edwards describe him very briefly as a rude, extreme, and slandering Calvinist who had a bitter debate with philosopher John Locke, the champion of reasonableness, peace, and toleration. This thesis does more than upend that synopsis. Although Edwards was not always the most diplomatic opponent, a close evaluation of his works demonstrates that he was most often respectful, fairly tolerant, and careful in his accusations. Had others followed his example, Church of England schisms could have been avoided.
- Published
- 2021
29. The quasi-uniformity condition for reproducing kernel element method meshes
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Collier, Nathan and Simkins, Jr., Daniel Craig
- Published
- 2009
- Full Text
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30. The Propagation and Amplification of Surface Waves
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Bowden, Daniel Craig, Bowden, Daniel Craig, Bowden, Daniel Craig, and Bowden, Daniel Craig
- Abstract
The observation of surface waves from cross-correlations of ambient noise has proven to be an invaluable tool for the recovery of seismic travel times. Such techniques allow the construction of 3D velocity models and subsequent geologic interpretations in regions where tomography would otherwise be difficult due to the paucity of seismicity and short seismic array deployment times. One such model is developed here for offshore southern California using an array of Ocean Bottom Seismometers to better understand the tectonic history of the region. However, for accurate hazard evaluation, characterizations of the spatial variability of ground motion amplitudes are also desired. Unfortunately, the amplitudes from noise cross-correlations are systematically biased by the spatial-, frequency- and temporal variability of noise sources. We demonstrate in this thesis that an ambient-noise based wavefront tracking technique using an array of stations can recover site-amplification and attenuation estimates successfully and robustly. This is applied on two different scales: to a very dense array of more than 5,000 geophones in the city of Long Beach, CA, and in a broader, continental scale to instruments from the USArray. Finally, we discuss the propagation of surface waves in relation to seismic hazard and site characterization. We point out that the amplitude response and peak frequency of ground motion will be different for a given site, depending on the type of wave being considered. This work should be considered by any future seismic hazard evaluation where surface waves may cause damage.
- Published
- 2018
31. The Expanding Computational Toolbox for Engineering Microbial Phenotypes at the Genome Scale
- Author
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Zielinski, Daniel Craig, Patel, Arjun, Palsson, Bernhard O, Zielinski, Daniel Craig, Patel, Arjun, and Palsson, Bernhard O
- Abstract
Microbial strains are being engineered for an increasingly diverse array of applications, from chemical production to human health. While traditional engineering disciplines are driven by predictive design tools, these tools have been difficult to build for biological design due to the complexity of biological systems and many unknowns of their quantitative behavior. However, due to many recent advances, the gap between design in biology and other engineering fields is closing. In this work, we discuss promising areas of development of computational tools for engineering microbial strains. We define five frontiers of active research: (1) Constraint-based modeling and metabolic network reconstruction, (2) Kinetics and thermodynamic modeling, (3) Protein structure analysis, (4) Genome sequence analysis, and (5) Regulatory network analysis. Experimental and machine learning drivers have enabled these methods to improve by leaps and bounds in both scope and accuracy. Modern strain design projects will require these tools to be comprehensively applied to the entire cell and efficiently integrated within a single workflow. We expect that these frontiers, enabled by the ongoing revolution of big data science, will drive forward more advanced and powerful strain engineering strategies.
- Published
- 2020
32. The Expanding Computational Toolbox for Engineering Microbial Phenotypes at the Genome Scale
- Author
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Zielinski, Daniel Craig, primary, Patel, Arjun, additional, and Palsson, Bernhard O., additional
- Published
- 2020
- Full Text
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33. ReCodLiver0.9: Overcoming Challenges in Genome-Scale Metabolic Reconstruction of a Non-model Species
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Hanna, Eileen Marie, primary, Zhang, Xiaokang, additional, Eide, Marta, additional, Fallahi, Shirin, additional, Furmanek, Tomasz, additional, Yadetie, Fekadu, additional, Zielinski, Daniel Craig, additional, Goksøyr, Anders, additional, and Jonassen, Inge, additional
- Published
- 2020
- Full Text
- View/download PDF
34. Intelligent Fitness : The Smart Way to Reboot Your Body and Get in Shape
- Author
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Simon Waterson, Daniel Craig, Simon Waterson, and Daniel Craig
- Subjects
- Exercise for men, Bodybuilding, Physical fitness for men, Physical fitness, Exercise
- Abstract
'Without Simon Waterson's help and guidance, I literally wouldn't have made it through fifteen years of playing James Bond... It's been an honor working with him.'—Daniel Craig _________________________Simon Waterson's job is to turn actors into athletes. Now you can learn how to transform your fitness and wellbeing with the film industry's most in-demand trainer. Simon's client list reads like a who's who of A-list actors. He has transformed Daniel Craig into the formidable James Bond for five blockbuster films, shaped Chris Evans into superhero Captain America, trained Chris Pratt for Guardians of the Galaxy and prepared actors such as Thandiwe Newton and John Boyega for the recent Star Wars films. From 3.30 a.m. training sessions in the desert with Jake Gyllenhaal to virtual workouts with Bryce Dallas Howard, Simon reveals the real training programs he used to take these actors to peak physical health. Sharing his practical and highly accessible approach to reimagining your body, Simon encourages you to focus on training, recovery and nutrition to build on your performance, rather than aesthetic.Packed full of behind-the-scenes insights, as well as 007 photographer Greg Williams'exclusive photographs, this is an essential training manual for any age and fitness level that will motivate you to reboot your body and train like a star.
- Published
- 2022
35. Preliminary Phase 1 Data on the Safety and Efficacy of a Novel PET Radiotracer, 124I-p5+14, for Imaging Systemic Amyloidosis
- Author
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Wall, Jonathan S., primary, Stuckey, Alan, additional, Martin, Emily B., additional, Richey, Tina, additional, Williams, Angela, additional, Wooliver, Daniel Craig, additional, Macy, Sallie, additional, Foster, James S., additional, Whittle, Bryan, additional, Geldrich, Robin, additional, Powell, Mark, additional, Fu, Yitong, additional, Powell, Dustin, additional, Osborne, Dustin, additional, Heidel, R. Eric, additional, Marine, Barbara, additional, Besozzi, Myrwood, additional, Ramchandren, Radhakrishnan, additional, Lands, Ronald H., additional, and Kennel, Stephen J., additional
- Published
- 2019
- Full Text
- View/download PDF
36. Differential Pressure Shunt for Simultaneous Diversion of Ventricular Fluid and Extracerebral Fluid
- Author
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Daniel Craig, Zach Folzenlogen, Ken R. Winston, and Kathryn A. Beauchamp
- Subjects
Male ,medicine.medical_specialty ,Adolescent ,Subdural Space ,Differential pressure ,Ventriculoperitoneal Shunt ,Cerebral Ventricles ,Young Adult ,Cerebrospinal Fluid Pressure ,Humans ,Medicine ,In patient ,Subdural space ,Child ,Cerebrospinal Fluid ,business.industry ,Infant ,General Medicine ,medicine.disease ,Cerebrospinal Fluid Shunts ,Hydrocephalus ,Shunt (medical) ,Surgery ,Shunting ,Catheter ,medicine.anatomical_structure ,Pediatrics, Perinatology and Child Health ,Female ,Neurology (clinical) ,Implant ,business - Abstract
Background/Aims: The management of extracerebral collections of fluid in patients with hydrocephalus can be problematic for either their simultaneous separate management or sequential management, each of which may require multiple surgeries and the management of external drains. The object of this report is to review the experience with a shunt configuration that simultaneously diverts ventricular fluid and extracerebral fluid, whether subdural or subarachnoid in location, through different outflow resistances. Methods: The medical records, including neuroimaging of patients with hydrocephalus and clinically significant extracerebral collections of low density who were managed by implanting a differential pressure type shunt, were retrospectively reviewed. Results: Four patients, 3 children and 1 adult, met inclusion criteria. Three had the entire differential pressure shunt implanted under 1 anesthetic, and 1 had a catheter inserted into the subdural space and connected into an existing ventriculoperitoneal shunt system. The extracerebral fluid collections cleared in all 4 patients, and the CSF shunt continued to function normally. Conclusion: A single surgical procedure to implant a differential pressure shunt can simultaneously drain and obliterate an extracerebral fluid collection while managing the hydrocephalus. Compared to routines that include external drainage, differential pressure shunting requires fewer surgeries, shorter hospitalization, with expected less expense.
- Published
- 2017
37. Full time trauma service leads to improved Level III trauma center outcomes
- Author
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Daniel, Craig O., West, T.A., Craig-Blanco, Phyllis S., Myers, John G., and Stewart, Ronald M.
- Subjects
Emergency medical services ,Health - Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.amjsurg.2010.07.026 Byline: Craig O. Daniel (a), T.A. West (a), Phyllis S. Craig-Blanco (a), John G. Myers (b), Ronald M. Stewart (b) Keywords: Outcomes; Rural; Trauma systems; Injury Abstract: Level III trauma centers are an effective component of a healthy trauma system. This study examined the effectiveness over time of a Level III trauma center in a predominately rural region. Author Affiliation: (a) Medical Center Hospital, 500 W. 4th, Odessa, TX 79761, USA (b) University of Texas Health Science Center at San Antonio, San Antonio, TX Article History: Received 10 March 2010; Revised 2 July 2010 Article Note: (footnote) No potential conflicts of interest relevant to this article were reported.
- Published
- 2010
38. Racial Stereotype Threat: A Critical Race Perspective
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Daniel Craig McCloud
- Subjects
Stereotype threat ,Race (biology) ,media_common.quotation_subject ,Critical race theory ,Perspective (graphical) ,Criminology ,Psychology ,Social psychology ,Racism ,media_common - Published
- 2018
39. Preliminary Phase 1 Data on the Safety and Efficacy of a Novel PET Radiotracer, 124I-p5+14, for Imaging Systemic Amyloidosis
- Author
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R. Eric Heidel, Alan Stuckey, Yitong Fu, Radhakrishnan Ramchandren, Tina Richey, Barbara Marine, Mark Powell, James S. Foster, Dustin Osborne, Robin Geldrich, Daniel Craig Wooliver, Dustin Powell, Myrwood C. Besozzi, Emily B. Martin, Stephen J. Kennel, Ronald H. Lands, Angela Williams, Jonathan S. Wall, Sallie Macy, and Bryan Whittle
- Subjects
Kidney ,Pathology ,medicine.medical_specialty ,medicine.diagnostic_test ,Amyloid ,business.industry ,Amyloidosis ,Immunology ,Renal function ,Cell Biology ,Hematology ,medicine.disease ,Biochemistry ,Amyloid disease ,medicine.anatomical_structure ,Biopsy ,Monoclonal ,medicine ,AL amyloidosis ,business - Abstract
Background: Systemic immunoglobulin light chain-associated amyloidosis (AL) is a rare disorder associated with plasma cell dyscrasias and the production of monoclonal free light chain proteins. Pathology results from the extracellular deposition of proteinaceous (amyloid) fibrils in association with proteoglycans and other serum derived proteins. The amyloid accumulates in abdominothoracic organs, notably the heart, liver, spleen, kidneys, as well as peripheral nerves leading to organ dysfunction and significant morbidity. At present, there are no radiotracers approved in the US for the non-invasive quantitative measurement of systemic AL amyloid disease. We have developed a synthetic polybasic peptide radiotracer, designated 124I-p5+14, which has been shown, in preclinical assays, to bind many forms of amyloid, including AL, ATTR, and ALECT2 (Wall, J.S. et al. (2015) Molecules, 20, 7657). The peptide binds, through multivalent electrostatic interactions, to the hypersulfated heparan sulfate glycosaminoglycans and potentially to the fibrillar constituents of amyloid deposits. Using SPECT and PET imaging of murine systemic amyloidosis, we have demonstrated the specific interaction of radioiodinated peptide p5+14 with amyloid in abdominothoracic organs and tissues. No detectable binding of p5+14 with amyloid-free tissues was observed. In light of these data, p5+14 was prepared for a first-in-human PET imaging study using iodine-124-labeled peptide (NCT 03678259). Methods: Patients >18 years of age with biopsy proven amyloidosis with adequate renal function and not requiring heparin therapy are eligible. Subjects receive Results: To date, 10 patients have been dosed and evaluated. No serious adverse events of any grade were noted. Organ-specific and whole body effective dosimetry were calculated using time activity curves generated from the initial cohort. The gender-averaged mean whole body effective dose attributed to 124I-p5+14 injection was estimated to be ~0.5 mSv/MBq. Blood pool clearance of the 124I-p5+14 was analyzed using a two phase exponential equation which yielded an excellent fit to the data (R2 > 0.99 for all data), with estimated fast half-life values of 11.8 min - 22.4 min, and a corresponding elimination half-life of between 667.8 min and 746.7 min. Analysis of PET images indicated retention of 124I-p5+14 in the heart, kidneys, liver, spleen, pancreas, bone marrow, lung, and adrenal gland of AL patients (Fig. 1 (A) Cardio-renal AL, and (B) Hepatosplenic AL amyloidosis). Cardiac uptake of the radiotracer was observed in 80% of AL patients (n = 5) who received ≥ 1 mCi 124I-p5+14, with a mean myocardium:blood pool ratio of 2.3 ± 0.5 in positive images. Additionally, liver, spleen and kidney retention of 124I-p5+14 was observed in 20%, 40%, and 60% of AL patients, respectively. Furthermore, retention of the radiotracer has been indicated in the heart, spleen and kidney in patients with ATTR and ALECT2--associated amyloidoses. Conclusion: Initial PET/CT image data indicate that 124I-p5+14 can provide quantitative detection of systemic AL amyloidosis in multiple organ systems and may have general utility in detecting and monitoring amyloid burden in many forms of amyloidosis. Acknowledgments: This study was supported in part by the National Heart Lung and Blood Institute, National Institutes of Health, through the Science Moving TowArds Research Translation and Therapy (SMARTT) program via the following contracts: HHSN268201600011C, HHSN268201600012C, and HHSN268201600014C, as well as by contributions from Gerdau to the ACTP Gift Fund at the UTGSM and support from UHS. In addition, we thank Michael Stabin, PhD, Brett Hines, Carmella Moody, PhD and Derry Ridgway, MD and the many patients for their support. Figure 1 Disclosures Wall: Solex LLC: Equity Ownership; University of Tennessee Research Foundation: Patents & Royalties. Stuckey:Solex LLC: Equity Ownership. Martin:Solex LLC: Equity Ownership. Richey:Solex LLC: Equity Ownership. Ramchandren:Sandoz-Novartis: Consultancy, Membership on an entity's Board of Directors or advisory committees; Seattle Genetics, Inc.: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Merck: Research Funding; Pharmacyclics LLC, an Abbvie company: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Janssen: Research Funding; Bristol-Myers Squibb: Consultancy, Membership on an entity's Board of Directors or advisory committees; Genentech: Research Funding. Kennel:University of Tennessee Research Foundation: Patents & Royalties; Solex LLC: Equity Ownership.
- Published
- 2019
40. Is Sugar-Free Chewing Gum Really Good For Your Teeth?6 Facts about It Here
- Author
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Daniel Craig Hetrelezis
- Subjects
Sugar free ,business.industry ,Dentistry ,Medicine ,General Medicine ,business ,Chewing gum - Published
- 2017
41. Presigmoid Approach to Dumbbell Trigeminal Schwannoma
- Author
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Katherine E. Kunigelis, Alexander Yang, Daniel Craig, A. Samy Youssef, and Samuel P. Gubbels
- Subjects
Trigeminal nerve ,dumbbell ,Hypesthesia ,medicine.diagnostic_test ,Petrous Apex ,business.industry ,cerebellopontine angle ,medicine.medical_treatment ,Magnetic resonance imaging ,Anatomy ,trigeminal schwannoma ,Cerebellopontine angle ,Skull Base: Operative Videos ,presigmoid ,medicine.anatomical_structure ,Posterior cranial fossa ,medicine ,Neurology (clinical) ,Headaches ,medicine.symptom ,business ,Craniotomy - Abstract
This case is a 15-year-old male, presenting with headaches, right face, and arm numbness, and ataxia. MRI (magnetic resonance imaging) revealed a large right sided dumbbell shaped lesion, extending into the middle and posterior fossa with compression of the brainstem consistent with a trigeminal schwannoma. Treatment options here would be a retrosigmoid suprameatal approach or a lateral presigmoid approach. Given the tumor extension into multiple compartments, a presigmoid craniotomy, combining a middle fossa approach with anterior petrosectomy, and retrolabyrinthine approach with posterior petrosectomy were used to maximize the direct access corridor for resection. The petrous apex was already expanded and remodeled by the tumor. Nerve fascicles preservation technique is paramount to the functional preservation of the trigeminal nerve. The extent of resection should be weighed against the anatomical functional integrity of the nerve. Near total resection is considered if that means more nerve preservation. Postoperatively, the patient had a slight (House–Brackman grade II) facial droop, which resolved over days and developed right trigeminal hypesthesia at several weeks. This case is presented to demonstrate a combined petrosectomy technique for resection of lesions extending into both the middle and posterior cranial fossa with near total resection and trigeminal nerve preservation.The link to the video can be found at: https://youtu.be/kA9GyFhL1dg.
- Published
- 2018
42. Representation theory of the global Cherednik algebra
- Author
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Pavel Etingof., Massachusetts Institute of Technology. Department of Mathematics., Thompson, Daniel (Daniel Craig), Pavel Etingof., Massachusetts Institute of Technology. Department of Mathematics., and Thompson, Daniel (Daniel Craig)
- Abstract
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Mathematics, 2017., Cataloged from PDF version of thesis., Includes bibliographical references (pages 69-71)., This thesis studies the representation theory of Cherednik algebras associated to a complex algebraic varieties which carries the action of a finite group. First, we prove that the Knizhnik-Zamolodchikov functor from the category of P-coherent modules for the Cherednik algebra to finite dimensional modules over the Hecke algebra is essentially surjective. Then we begin to use this result to study the analog of category 0 for Cherednik algebras on Riemann surfaces and on products of elliptic curves. In particular we give conditions on the parameters under which this category 0 analog is nonzero. Our next goal is to generalize several basic results from the theory of D-modules to the representation theory of rational Cherednik algebras. We relate characterizations of holonomic modules in terms of singular support and Gelfand-Kirillov dimension. We study pullback, pushforward, and dual on the derived category of (holonomic) Cherednik modules for certain classes of maps between varieties. We prove, in the case of generic parameters for the rational Cherednik algebra, that pushforward with respect to an open affine inclusion preserves holonomicity. Finally, we relate the global sections algebra of the sheaf of Cherednik algebras associated to a smooth quadric hypersurface of Pn to the Dunkl angular momentum algebra of Feigin-Hakobyan. In particular, this lets us relate the angular momentum algebra for a rank 3 Coxeter group to the rank 2 symplectic reflection algebra for a corresponding finite subgroup of SL2., by Daniel Thompson., Ph. D.
- Published
- 2017
43. Intrinsic integral representations and boundary theory for superharmonic measures of a random walk
- Author
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Daniel Craig. Sloughter
- Published
- 2016
44. Photochemistry and transport of tropospheric ozone and its precursors in urban and remote environments
- Author
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Anderson, Daniel Craig
- Subjects
biomass burning ,Atmospheric sciences ,ozone ,Atmospheric chemistry ,formaldehyde ,carbon monoxide - Abstract
Tropospheric ozone (O3) adversely affects human health, reduces crop yields, and contributes to climate forcing. To limit these effects, the processes controlling O3 abundance as well as that of its precursor molecules must be fully characterized. Here, I examine three facets of O3 production, both in heavily polluted and remote environments. First, using in situ observations from the DISCOVER-AQ field campaign in the Baltimore/Washington region, I evaluate the emissions of the O3 precursors CO and NOx (NOx = NO + NO2) in the National Emissions Inventory (NEI). I find that CO/NOx emissions ratios derived from observations are 21% higher than those predicted by the NEI. Comparisons to output from the CMAQ model suggest that CO in the NEI is accurate within 15 ± 11%, while NOx emissions are overestimated by 51-70%, likely due to errors in mobile sources. These results imply that ambient ozone concentrations will respond more efficiently to NOx controls than current models suggest. I then investigate the source of high O3 and low H2O structures in the Tropical Western Pacific (TWP). A combination of in situ observations, satellite data, and models show that the high O3 results from photochemical production in biomass burning plumes from fires in tropical Southeast Asia and Central Africa; the low relative humidity results from large-scale descent in the tropics. Because these structures have frequently been attributed to mid-latitude pollution, biomass burning in the tropics likely contributes more to the radiative forcing of climate than previously believed. Finally, I evaluate the processes controlling formaldehyde (HCHO) in the TWP. Convective transport of near surface HCHO leads to a 33% increase in upper tropospheric HCHO mixing ratios; convection also likely increases upper tropospheric CH3OOH to ~230 pptv, enough to maintain background HCHO at ~75 pptv. The long-range transport of polluted air, with NO four times the convectively controlled background, intensifies the conversion of HO2 to OH, increasing OH by a factor of 1.4. Comparisons between the global chemistry model CAM-Chem and observations show that consistent underestimates of HCHO by CAM-Chem throughout the troposphere result from underestimates in both NO and acetaldehyde.
- Published
- 2016
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- View/download PDF
45. An Overview of Evidence-Based Support for the Therapeutic Use of Music in Occupational Therapy
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Daniel Craig
- Subjects
Occupational Therapy ,General Medicine - Published
- 2008
46. A Peptide-Fc Opsonin with Pan-Amyloid Reactivity
- Author
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Foster, James S., primary, Williams, Angela D., additional, Macy, Sallie, additional, Richey, Tina, additional, Stuckey, Alan, additional, Wooliver, Daniel Craig, additional, Koul-Tiwari, Richa, additional, Martin, Emily B., additional, Kennel, Stephen J., additional, and Wall, Jonathan S., additional
- Published
- 2017
- Full Text
- View/download PDF
47. Is Sugar-Free Chewing Gum Really Good For Your Teeth?6 Facts about It Here
- Author
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Hetrelezis, Daniel Craig, primary
- Published
- 2017
- Full Text
- View/download PDF
48. The Power of the Woods: A Memoir
- Author
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McCool, Daniel Craig, primary
- Published
- 2017
- Full Text
- View/download PDF
49. Novice Lifters Exhibit A More Kyphotic Lifting Posture Than Experienced Lifters In Straight-Leg Lifting
- Author
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Alice Elizabeth Riley, Neena K. Sharma, Sandra A. Billinger, Timothy Daniel Craig, and Sara E. Wilson
- Subjects
musculoskeletal diseases ,Adult ,Male ,medicine.medical_specialty ,Lifting ,Posture ,Biomedical Engineering ,Biophysics ,Article ,Young Adult ,Lumbar ,Physical medicine and rehabilitation ,medicine ,Humans ,Orthopedics and Sports Medicine ,Range of Motion, Articular ,Leg ,Lumbar Vertebrae ,business.industry ,Rehabilitation ,Significant difference ,Torso ,musculoskeletal system ,Low back pain ,body regions ,medicine.anatomical_structure ,Physical therapy ,Female ,medicine.symptom ,Range of motion ,business ,human activities - Abstract
As torso flexion and repetitive lifting are known risk factors for low back pain and injury, it is important to investigate lifting techniques that might reduce injury during repetitive lifting. By normalizing lumbar posture to a subject's range of motion (ROM), as a function of torso flexion, this research examined when subjects approached their range of motion limits during dynamic lifting tasks. For this study, it was hypothesized that experienced lifters would maintain a more neutral lumbar angle relative to their range of motion, while novice lifters would approach the limits of their lumbar ROM during the extension phase of a straight-leg lift. The results show a statistically significant difference in lifting patterns for these two groups supporting this hypothesis. The novice group maintained a much more kyphotic lumbar angle for both the flexion (74% of the lumbar angle ROM) and extension phases (86% of the lumbar angle ROM) of the lifting cycle, while the experienced group retained a more neutral curvature throughout the entire lifting cycle (37% of lumbar angle ROM in flexion and 48% of lumbar angle ROM in extension). By approaching the limits of their range of motion, the novice lifters could be at greater risk of injury by placing greater loads on the supporting soft tissues of the spine. Future research should examine whether training subjects to assume more neutral postures during lifting could indeed lower injury risks.
- Published
- 2015
50. Lumbar Puncture
- Author
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Daniel Craig and Kathryn Beauchamp
- Published
- 2015
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