1. Ancient genomes from present-day France unveil 7,000 years of its demographic history
- Author
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Jérôme Dubouloz, Fanny Chenal, Bertrand Perrin, Florent Mazière, Alexandre Beylier, Samantha Brunel, Bernard Dedet, Estelle Pinard, Vincent Riquier, Eric Gailledrat, Ivan Praud, Luc Vergnaud, Véronique Fabre, Stéphanie Desbrosse-Degobertière, Elsa Ciesielski, Sophie Desenne, Thierry Grange, E. Andrew Bennett, Damien Garraud, Hélène Barrand Emam, Eva-Maria Geigl, Benoit Sendra, Jean Guilaine, Elisabeth Vauquelin, Gilles Escalon, Corinne Thevenet, Henri Duday, François Lambach, Suzanne Plouin, Mélanie Pruvost, Sandrine Thiol, Sébastien Goepfert, Yves Gleize, Muriel Gandelin, Lamys Hachem, Isabelle Richard, Michael Ilett, Réjane Roure, Laurent Cardin, Bruno Boulestin, Fabien Convertini, Institut Jacques Monod (IJM (UMR_7592)), Université de Paris (UP)-Centre National de la Recherche Scientifique (CNRS), Antea-Archéologie, Habsheim, Archéologie et histoire ancienne : Méditerranée - Europe (ARCHIMEDE), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Sète agglopôle Méditerranée, Archéologie des Sociétés Méditerranéennes (ASM), Université Paul-Valéry - Montpellier 3 (UPVM)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC), De la Préhistoire à l'Actuel : Culture, Environnement et Anthropologie (PACEA), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Institut national de recherches archéologiques préventives (Inrap), Trajectoires - UMR 8215, Université Paris 1 Panthéon-Sorbonne (UP1)-Centre National de la Recherche Scientifique (CNRS), Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés (TRACES), École des hautes études en sciences sociales (EHESS)-Université Toulouse - Jean Jaurès (UT2J)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Culture et Environnements, Préhistoire, Antiquité, Moyen-Age (CEPAM), Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB)
- Subjects
Gene Flow ,Male ,population genomics ,[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory ,Demographic history ,Human Migration ,Population ,engineering.material ,Present day ,migration ,DNA, Mitochondrial ,Gene flow ,Evolution, Molecular ,Population genomics ,03 medical and health sciences ,Bronze Age ,Humans ,0601 history and archaeology ,DNA, Ancient ,Bronze ,Neolithic ,Mesolithic ,030304 developmental biology ,0303 health sciences ,Chromosomes, Human, Y ,Polymorphism, Genetic ,Multidisciplinary ,060102 archaeology ,Genome, Human ,06 humanities and the arts ,Biological Sciences ,Geography ,paleogenomics ,[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics ,Iron Age ,Evolutionary biology ,engineering ,Female ,France ,Protohistory - Abstract
International audience; Genomic studies conducted on ancient individuals across Europe have revealed how migrations have contributed to its present genetic landscape, but the territory of present-day France has yet to be connected to the broader European picture. We generated a large dataset comprising the complete mitochondrial genomes, Y chromosome markers and genotypes on a number of nuclear loci of interest of 243 individuals sampled across present-day France over a period spanning 7,000 years, complemented with a partially overlapping dataset of 58 low-coverage genomes. This panel provides a high-resolution transect of the dynamics of maternal and paternal lineages in France as well as of autosomal genotypes. Parental lineages and genomic data both revealed demographic patterns in France for the Neolithic and Bronze Age transitions consistent with neighboring regions, first with a migration wave of Anatolian farmers followed by varying degrees of admixture with autochthonous hunter-gatherers, then substantial gene flow from individuals deriving part of their ancestry from the Pontic Steppe at the onset of the Bronze Age. Our data have also highlighted the persistence of the Magdalenian-associated ancestry in hunter-gatherer populations outside of Spain and thus provide arguments for an expansion of these populations at the end of the Paleolithic period more northerly than what has been described so far. Finally, no major demographic changes were detected during the transition between the Bronze and Iron Ages.
- Published
- 2020
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