1. Distinction between SGA and FGR by means of fetal umbilical vein flow and maternal hemodynamics
- Author
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I. Pisani, D. Farsetti, Giulia Gagliardi, Herbert Valensise, Francesca Pometti, Damiano Lo Presti, Gian Paolo Novelli, Barbara Vasapollo, and G. M. Tiralongo
- Subjects
Umbilical Veins ,Cardiac output ,medicine.medical_specialty ,systemic vascular resistance ,Gestational Age ,030204 cardiovascular system & hematology ,Venous flow ,Ultrasonography, Prenatal ,Umbilical vein ,small for gestational age ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,Internal medicine ,medicine ,Fetal growth ,Humans ,maternal hemodynamics ,Fetal Growth Retardation ,030219 obstetrics & reproductive medicine ,business.industry ,Fetal growth restriction ,Infant, Newborn ,Hemodynamics ,cardiac output ,Obstetrics and Gynecology ,medicine.disease ,umbilical vein blood flow ,medicine.anatomical_structure ,Fetal Weight ,Settore MED/40 ,Infant, Small for Gestational Age ,Pediatrics, Perinatology and Child Health ,Maternal hemodynamics ,Vascular resistance ,Cardiology ,Small for gestational age ,Female ,business - Abstract
To improve identification of fetal growth restriction (FGR) by means of umbilical venous flow (QUV) and maternal hemodynamics, including systemic vascular resistance (SVR) and cardiac output (CO), in order to distinguish between FGR and SGA.We enrolled 68 pregnancies (36 SGA, 8 early FGR and 24 late FGR) who underwent a complete fetal hemodynamic examination including QUV and a noninvasive maternal hemodynamics assessment by means of USCOM.In comparison with SGA, QUV and corrected for estimated fetal weight QUV (cQUV) were significantly lower in early and late-FGR. In addition, maternal CO was lower in early and late-FGR, while SVR was lower only in early-onset FGR. According to ROC analysis, cQUV centile (AUC 0.92, 0.72) was the best parameter for the prediction of SGA before and after 32 weeks, followed by SVR and CO. For all parameters, the prediction was always better in the case of early-onset FGR32 weeks.UV flow and maternal hemodynamics examination are useful tools to accurately discern between SGA and FGR.
- Published
- 2021