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The present invention relates to oleaginous yeast cells for the production of fatty alcohols and derivatives thereof, in particular desaturated fatty alcohols, desaturated fatty acyl acetates and desaturated fatty aldehydes. Also provided are methods for obtaining such compounds, which are useful in pheromone compositions.

The present disclosure relates to methods for production of (Z)-11-hexadecen-1-ol in a yeast cell using desaturases and fatty acyl-CoA reductase. Also disclosed are methods for production of (Z)-11-hexadecenal in a yeast cell. Also disclosed are methods for production of (Z)-11-hexadecen-1-yl acetate in a yeast cell. The disclosure also provides for nucleic acid constructs and yeast cells useful for performing the present methods, as well as to pheromone compositions.

The present invention relates to the production of compounds comprised in pheromones, in particular moth pheromones, such as desaturated fatty alcohols and desaturated fatty acyl acetates and derivatives thereof, from a yeast cell.

Aalborg University applies a problem-based learning model. Each semester all students form groups. Group members formulate and agree upon a problem they want to address, within their course of study, and write a long report on their findings (length depends on the year of study, the number of group members etc.). Key principles for the choice problem is praxis-orientation, interdisciplinarity, and contextualisation. To facilitate inter-disciplinarity two supervisors – a disciplinary and a contextual – might be associated with student groups. A team of seven undergraduate students of Chemistry, Environmental technology and Biotechnology study-programme at Aalborg University, and thei contextual superviso worked on the problem “What is the risk of methane migration into houses situated on the terminated landfill “Skrænten” in Hjørring, Denmark?” The work consisted of both a technical part and a contextual part. In the technical part we investigated the theoretical foundation of methane production in landfills and we measured the concentration of methane at different places at the landfill Skrænten in Hjørring. In the contextual part a NUSAP analysis was done on the risk assessment of the gas-producing landfill that had been carried out by the local authorities.