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6. List of contributors

Author

Acosta-Lagrada, Levita, primary, Ades, Gary, additional, Ahlers, Nick, additional, Akrim, Faraz, additional, Alempijevic, Daniel, additional, Alvarado, Dexter, additional, Andleeb, Shaista, additional, Assovi, Brou Guy-Mathieu, additional, Ayebare, Sam, additional, Billet, Guillaume, additional, Bonebrake, Timothy C., additional, Boopal, Anbarasi, additional, Bruce, Tom, additional, Burgess, Gayle, additional, Cabana, Francis, additional, Cassidy, Rod, additional, Cassidy, Tamar, additional, Challender, Daniel W.S., additional, Chao, Jung-Tai, additional, Cheema, Shavez, additional, Chen, Tina Ting-Yu, additional, Cheng, Wenda, additional, Chin, Jason Shih-Chien, additional, Chong, Ju Lian, additional, Chung, Yi Fei, additional, Cooney, Rosie, additional, Dalton, Desire Lee, additional, Davenport, Tim R.B., additional, Di Minin, Enrico, additional, Dublin, Holly, additional, Ferreira-Cardoso, Sérgio, additional, Fletcher, Louise, additional, Fowler, Andrew, additional, Gaubert, Philippe, additional, Gaudin, Timothy J., additional, Gudehus, Maja, additional, Hai, Lam Kim, additional, Harrop, Stuart R., additional, Hart, John, additional, Hart, Terese, additional, Hausmann, Anna, additional, Hautier, Lionel, additional, Hega, Martin, additional, Heighton, Sean P., additional, Heinrich, Sarah, additional, Hoffmann, Michael, additional, Hoffmann, Rachel, additional, Ichu, Ichu Godwill, additional, Ingram, Daniel J., additional, Irshad, Nausheen, additional, Jang-Liaw, Nian-Hong, additional, Jansen, Raymond, additional, Jiang, Zhigang, additional, Jimerson, Jessica, additional, Kao, Jim, additional, Kaspal, Prativa, additional, Katsis, Lydia K.D., additional, Khatiwada, Ambika P., additional, Kotze, Antoinette, additional, Kurniawan, Ade, additional, Lapuente, Juan, additional, Lawrence, Natalie, additional, Lee, Paige B., additional, Lees, Caroline, additional, Li, Chenny, additional, Li, Hou-Feng, additional, Li, Jocy Yu-Wen, additional, Lim, Norman T-L, additional, Lin, Chung-Chi, additional, Lo, Flora Hsuan-Yi, additional, Lourens, Karin, additional, Luz, Sonja, additional, Mahmood, Tariq, additional, Maisels, Fiona, additional, Mills, David, additional, Mohapatra, Rajesh Kumar, additional, Morin, Dana J., additional, Nash, Helen C., additional, Ndjassi, Constant, additional, Nebe, Bruno, additional, Niskanen, Leo, additional, Nixon, Stuart, additional, Ogden, Rob, additional, Olmedo, Alegria, additional, Olsson, Annette, additional, O’Criodain, Colman, additional, Panaino, Wendy, additional, Panda, Sudarsan, additional, Panjang, Elisa, additional, Parker, Keri, additional, Paudel, Kumar, additional, Perera, Priyan, additional, Pietersen, Darren W., additional, Plowman, Christian, additional, Rankin, Paul, additional, Rao, Madhu, additional, Roberts, Amy, additional, Roe, Dilys, additional, Schoppe, Sabine, additional, Semiadi, Gono, additional, Sharma, Sandhya, additional, Shaw, Debbie, additional, Shepherd, Chris R., additional, Shirley, Matthew H., additional, Skinner, Diane, additional, Sodeinde, Olufemi, additional, Sodsai, Withoon, additional, Soewu, Durojaye, additional, Strange, Bee Choo Ng, additional, Sun, Nick Ching-Min, additional, Suwal, Tulshi Laxmi, additional, Swart, Jonathan, additional, Thapa, Sanjan, additional, Thomson, Paul, additional, Traylor-Holzer, Kathy, additional, ‘t Sas-Rolfes, Michael, additional, Veríssimo, Diogo, additional, Vishwanath, Akshay, additional, Walsh, Martin T., additional, Waseem, Muhammad, additional, Waterman, Carly, additional, Wible, John R., additional, Wicker, Leanne Vivian, additional, Willcox, Daniel, additional, Withers, Oliver, additional, Wright, Nicci, additional, Wright, Wendy, additional, Wu, Shibao, additional, Xing, Shuang, additional, Yu, Yishuang, additional, Zhang, Fuhua, additional, Zhang, Mingxia, additional, Zhou, Youlong, additional, and Zoltani, Tenke, additional

Published
2020
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11. Genomic analyses show extremely perilous conservation status of African and Asiatic cheetahs (Acinonyx jubatus)

Author

Prost, Stefan, primary, Machado, Ana Paula, additional, Zumbroich, Julia, additional, Preier, Lisa, additional, Mahtani‐Williams, Sarita, additional, Meissner, Rene, additional, Guschanski, Katerina, additional, Brealey, Jaelle C., additional, Fernandes, Carlos Rodríguez, additional, Vercammen, Paul, additional, Hunter, Luke T. B., additional, Abramov, Alexei V., additional, Plasil, Martin, additional, Horin, Petr, additional, Godsall‐Bottriell, Lena, additional, Bottriell, Paul, additional, Dalton, Desire Lee, additional, Kotze, Antoinette, additional, and Burger, Pamela Anna, additional

Published
2022
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14. Conservation Genomic Analyses of African and Asiatic Cheetahs (Acinonyx jubatus) Across Their Current and Historical Species Range

Author

Prost, Stefan, primary, Machado, Ana Paula, additional, Zumbroich, Julia, additional, Preier, Lisa, additional, Mahtani-Williams, Sarita, additional, Meissner, Rene, additional, Guschanski, Katerina, additional, Brealey, Jaelle C., additional, Fernandes, Carlos, additional, Vercammen, Paul, additional, Hunter, Luke T. B., additional, Abramov, Alexei V., additional, Godsall-Bottriell, Lena, additional, Bottriell, Paul, additional, Dalton, Desire Lee, additional, Kotze, Antoinette, additional, and Burger, Pamela Anna, additional

Published
2020
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16. Biomes, geology and past climate drive speciation of laminate-toothed rats on South African mountains (Murinae: Otomys).

Author

Taylor, Peter John, Kearney, Teresa, Dalton, Desire Lee, Chakona, Gamuchirai, Kelly, Christopher M R, and Barker, Nigel P

Subjects
GRASSLANDS, BIOMES, GENETIC speciation, GEOLOGICAL formations, MITOCHONDRIAL DNA
Abstract

Mitochondrial DNA sequences (1137 bp) of the cytochrome b gene and craniodental and craniometric data were used to investigate the evolutionary relationships of six putative rodent taxa of Otomys (family Muridae: subfamily Murinae: tribe Otomyini) co-occurring in the Western Cape and Eastern Cape provinces of South Africa. Phylogenetic analysis of 20 new sequences together with craniodental and craniometric characters of 94 adult skulls reveal the existence of a unique lineage of Otomys cf. karoensis (named herein Otomys willani sp. nov.) from the Sneeuberg Centre of Floristic Endemism in the southern Drakensberg Mountain Range. Craniometric analysis distinguished O. karoensis from O. willani and identified a further four localities in the range of the latter species. We document southern range extensions of both Sloggett's ice rat, Otomys sloggetti , and the vlei rat Otomys auratus to the Sneeuberg Mountain Range, in addition to appreciable genetic divergence between Sneeuberg and southern and central Drakensberg populations of O. sloggetti. Our results demonstrate parallel patterns of cryptic speciation in two co-occurring species complexes (Otomys irroratus s.l. and O. karoensis s.l.) associated closely with the boundaries of biomes (fynbos vs. grassland biomes) and geological formations (Cape Fold Belt vs. Great Escarpment). [ABSTRACT FROM AUTHOR]

Published
2020
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17. Screening of the RYR1 gene in malignant hyperthermia probands from South Africa indicates towards a novel epigenetic eatiology in this population / by Desiré Lee Dalton

Author

Dalton, Desire Lee

Abstract

Malignant hyperthermia (MH) is an autosomal dominant, potentially lethal pharmacogenetic disorder of skeletal muscle, which is elicited by exposure to volatile anaesthetics and depolarising muscle relaxants. Susceptible individuals appear clinically normal, but may present with a hypermetabolic crisis and muscle contracture when exposed to triggering substances that elicit excessive release of calcium ions from the sarcoplasmic reticulum. Diagnosis of MH susceptibility is currently made via the in vitro contracture test. Genetically, in more than 50% of the affected families, MH occurs due to alterations in the skeletal muscle ryanodine receptor gene (RYR1) on chromosome 19q13.1. However, the disorder is genetically heterogeneous, as six other loci have to date been associated with MH susceptibility (MHS). Thus far, molecular tests have focused on three mutation hotspots of the RYR1 gene, which refer to regions that are more frequently mutated. Screening the entire RYR1 has led to a higher detection rate in a variety of populations. In this study the entire coding region of the RYR1 gene was screened via sequencing for novel or reported alterations for the first time in 15 South African probands. Eight different RYR1 alterations were observed in seven MHS South African probands, six of which were previously reported and two of which were novel. Compound heterozygous alterations and alterations outside the mutation hotspots were detected. Screening of the entire coding region of the RYR1 gene is crucial for genetic investigations into MHS. It was postulated that MH in the South African population is due to multifactorial inheritance in which a network of several genetic, environmental and epigenetic factors interact and cumulatively result in the development of the MH phenotype. Data generated in this study highlight the complexity of this disorder, further supporting a novel epigenetic aetiology for MH in the South African population. Thesis (Ph.D. (Biochemistry))--North-West University, Potchefstroom Campus, 2008.

Published
2007

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