24 results on '"Dalfrà, Maria G."'
Search Results
2. Correction to: The Effects of Lifestyle and/or Vitamin D Supplementation Interventions on Pregnancy Outcomes: What Have we Learned from the DALI Studies?
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Harreiter, Jürgen, Desoye, Gernot, van Poppel, Mireille N. M., Kautzky-Willer, Alexandra, Dunne, Fidelma, Corcoy, Rosa, Devlieger, Roland, Simmons, David, Adelantado, Juan M., Damm, Peter, Mathiesen, Elizabeth Reinhardt, Jensen, Dorte Moeller, Anderson, Lise Lotte T., Lapolla, Annunziata, Dalfrà, Maria G., Bertolotto, Alessandra, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David J., and Snoek, Frank J.
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- 2020
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3. The Effects of Lifestyle and/or Vitamin D Supplementation Interventions on Pregnancy Outcomes: What Have We Learned from the DALI Studies?
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Harreiter, Jürgen, Desoye, Gernot, van Poppel, Mireille N. M., Kautzky-Willer, Alexandra, Dunne, Fidelma, Corcoy, Rosa, Devlieger, Roland, Simmons, David, Adelantado, Juan M., Damm, Peter, Mathiesen, Elizabeth Reinhardt, Jensen, Dorte Moeller, Anderson, Lise Lotte T., Lapolla, Annunziata, Dalfrà, Maria G., Bertolotto, Alessandra, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David J., and Snoek, Frank J.
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- 2019
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4. Hundred Years of Insulin Therapy: Purified Early Insulins
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Lapolla, Annunziata and Dalfrà, Maria G.
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- 2020
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5. Corrigendum to 'Performance of early pregnancy HbA1c for predicting gestational diabetes mellitus and adverse pregnancy outcomes in obese European women' [Diab. Res. Clin. Pract. 168 (2020) 108378](S0168822720306318)(10.1016/j.diabres.2020.108378)
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Immanuel, Jincy, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Adelantado, Juan M., Devlieger, Roland, Lapolla, Annunziata, Dalfra, Maria G., Adelantado, Alessandra, Damm, Peter, Mathiesen, Elizabeth Reinhardt, Jensen, Dorte Moeller, Anderson, Lise Lotte T., Dalfrà, Maria G., Bertolotto, Alessandra, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David J., and Snoek, Frank J.
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The authors regret that a few lines in Tables 1 and 2 were formatted incorrectly in the published version of the article with numbers all appearing in one line instead of being in separate lines. The correctly formatted tables are shown below. The authors would like to apologise for any inconvenience caused.
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- 2021
6. Correction to: Reldesemtiv in Patients with Spinal Muscular Atrophy: a Phase 2 Hypothesis-Generating Study (Neurotherapeutics, (2021), 18, 2, (1127-1136), 10.1007/s13311-020-01004-3)
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Rudnicki, Stacy A., Andrews, Jinsy A., Duong, Tina, Cockroft, Bettina M., Malik, Fady I., Meng, Lisa, Wei, Jenny, Wolff, Andrew A., Adelantado, Angela, Damm, Peter, Mathiesen, Elizabeth Reinhardt, Jensen, Dorte Moeller, Anderson, Lise Lotte T., Lapolla, Annunziata, Dalfrà, Maria G., Bertolotto, Alessandra, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David J., and Snoek, Frank J.
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This article has been updated to add the author Richard S. Finkel. The original article has been corrected.
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- 2021
7. Correction to: The Effects of Lifestyle and/or Vitamin D Supplementation Interventions on Pregnancy Outcomes: What Have we Learned from the DALI Studies? (Current Diabetes Reports, (2019), 19, 12, (162), 10.1007/s11892-019-1282-7)
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Harreiter, Jürgen, Desoye, Gernot, van Poppel, Mireille N M, Kautzky-Willer, Alexandra, Dunne, Fidelma, Corcoy, Rosa, Devlieger, Roland, Simmons, David, Adelantado, Juan M, Damm, Peter, Mathiesen, Elizabeth Reinhardt, Jensen, Dorte Moeller, Anderson, Lise Lotte T, Lapolla, Annunziata, Dalfrà, Maria G, Bertolotto, Alessandra, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David J, and Snoek, Frank J
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The original version of this review article unfortunately contained a mistake.
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- 2020
8. Deflazacort versus prednisone/prednisolone for maintaining motor function and delaying loss of ambulation: A post HOC analysis from the ACT DMD trial
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Shieh, Perry B., McIntosh, Joseph, Jin, Fengbin, Souza, Marcio, Elfring, Gary, Narayanan, Siva, Trifillis, Panayiota, Harreiter, Stuart W., van Assche, Andre, Devlieger, Roland, Timmerman, Dirk, Hill, David, Damm, Peter, Mathiesen, Elisabeth R., Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Rebollo, Pablo, Lapolla, Annunziata, Dalfrà, Maria G., Del Prato, Stefano, Bertolotto, Alessandra, Dunne, Fidelma, Jensen, Dorte M., Andersen, Liselotte, and Snoek, Frank J.
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Male ,muscular dystrophy ,0301 basic medicine ,Adolescent ,Physiology ,Prednisolone ,Duchenne muscular dystrophy ,Anti-Inflammatory Agents ,Walk Test ,Walking ,Placebo ,Dystrophin ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,0302 clinical medicine ,Double-Blind Method ,Pregnenediones ,Clinical Research ,Prednisone ,Physiology (medical) ,Post-hoc analysis ,medicine ,Humans ,Muscular dystrophy ,Child ,deflazacort ,business.industry ,Deflazacort ,Age Factors ,medicine.disease ,Confidence interval ,Muscular Dystrophy, Duchenne ,030104 developmental biology ,Anesthesia ,prednisone ,Female ,Neurology (clinical) ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Introduction: ACT DMD was a 48‐week trial of ataluren for nonsense mutation Duchenne muscular dystrophy (nmDMD). Patients received corticosteroids for ≥6 months at entry and stable regimens throughout study. This post hoc analysis compares efficacy and safety for deflazacort and prednisone/prednisolone in the placebo arm. Methods: Patients received deflazacort (n = 53) or prednisone/prednisolone (n = 61). Endpoints included change from baseline in 6‐minute walk distance (6MWD), timed function tests, estimated age at loss of ambulation (extrapolated from 6MWD). Results: Mean changes in 6MWD were ‐39.0 m (deflazacort; 95% confidence limit [CL], ‐68.85, ‐9.17) and ‐70.6 m (prednisone/prednisolone; 95% CL, ‐97.16, ‐44.02). Mean changes in 4‐stair climb were 3.79 s (deflazacort; 95% CL, 1.54, 6.03) and 6.67 s (prednisone/prednisolone; 95% CL, 4.69, 8.64). Conclusions: This analysis, limited by its post hoc nature, suggests greater preservation of 6MWD and 4‐stair climb with deflazacort vs. prednisone/prednisolone. A head‐to‐head comparison will better define these differences. Muscle Nerve 58: 639–645, 2018
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- 2018
9. Correlates of poor mental health in early pregnancy in obese European women
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Sattler, Matteo C., primary, Jelsma, Judith G. M., additional, Bogaerts, Annick, additional, Simmons, David, additional, Desoye, Gernot, additional, Corcoy, Rosa, additional, Adelantado, Juan M., additional, Kautzky-Willer, Alexandra, additional, Harreiter, Jürgen, additional, van Assche, Frans A., additional, Devlieger, Roland, additional, Jans, Goele, additional, Galjaard, Sander, additional, Hill, David, additional, Damm, Peter, additional, Mathiesen, Elisabeth R., additional, Wender-Ozegowska, Ewa, additional, Zawiejska, Agnieszka, additional, Blumska, Kinga, additional, Lapolla, Annunziata, additional, Dalfrà, Maria G., additional, Bertolotto, Alessandra, additional, Dunne, Fidelma, additional, Jensen, Dorte M., additional, Andersen, Lise Lotte T., additional, Snoek, Frank J., additional, and van Poppel, Mireille N. M., additional
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- 2017
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10. BMC Pregnancy and Childbirth / Correlates of poor mental health in early pregnancy in obese European women
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van Poppel, Mireille N. M., van Poppel, Mireille N. M., Snoek, Frank J., Andersen, Lise Lotte T., Jensen,, Dorte M., Dunne, Fidelma, Bertolotto, Alessandra, Dalfrà, Maria G., Lapolla, Annunziata, Blumska, Kinga, Zawiejska, Agnieszka, Wender-Ozegowska, Ewa, Mathiesen, Elisabeth R., Damm,, Peter, Hill, David, Galjaard, Sander, Jans, Goele, Devlieger,, Roland, van Assche, Frans A., Harreiter, Jürgen, Kautzky-Willer,, Alexandra, Adelantado, Juan M., Corcoy, Rosa, Desoye, Gernot, Simmons,, David, Bogaerts, Annick, van Poppel, Mireille N. M., van Poppel, Mireille N. M., Snoek, Frank J., Andersen, Lise Lotte T., Jensen,, Dorte M., Dunne, Fidelma, Bertolotto, Alessandra, Dalfrà, Maria G., Lapolla, Annunziata, Blumska, Kinga, Zawiejska, Agnieszka, Wender-Ozegowska, Ewa, Mathiesen, Elisabeth R., Damm,, Peter, Hill, David, Galjaard, Sander, Jans, Goele, Devlieger,, Roland, van Assche, Frans A., Harreiter, Jürgen, Kautzky-Willer,, Alexandra, Adelantado, Juan M., Corcoy, Rosa, Desoye, Gernot, Simmons,, David, and Bogaerts, Annick
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Background Depression during pregnancy is associated with higher maternal morbidity and mortality, and subsequent possible adverse effects on the cognitive, emotional and behavioral development of the child. The aim of the study was to identify maternal characteristics associated with poor mental health, in a group of overweight/obese pregnant women in nine European countries, and thus, to contribute to better recognition and intervention for maternal depression. Methods In this cross-sectional observational study, baseline data from early pregnancy (< 20 weeks) of the DALI (Vitamin D and Lifestyle Intervention for gestational diabetes mellitus prevention) study were analyzed. Maternal mental health was assessed with the World Health Organization Well-Being Index (WHO–5). Women were classified as having a low (WHO–5 ≤ 50) or high wellbeing. Results. A total of 735 pregnant women were included. The prevalence of having a low wellbeing was 27.2%, 95% CI [24.0, 30.4]. Multivariate analysis showed independent associations between low wellbeing and European ethnicity, OR = .44, 95% CI [.25, .77], shift work, OR = 1.81, 95% CI [1.11, 2.93], insufficient sleep, OR = 3.30, 95% CI [1.96, 5.55], self-efficacy, OR = .95, 95% CI [.92, .98], social support, OR = .94, 95% CI [.90, .99], and pregnancy-related worries (socioeconomic: OR = 1.08, 95% CI [1.02, 1.15]; health: OR = 1.06, 95% CI [1.01, 1.11]; relationship: OR = 1.17, 95% CI [1.05, 1.31]). Conclusions Mental health problems are common in European overweight/obese pregnant women. The identified correlates might help in early recognition and subsequent treatment of poor mental health problems during pregnancy. This is important to reduce the unfavorable effects of poor mental health on pregnancy outcomes. Trial registration
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- 2017
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11. Is a motivational interviewing based lifestyle intervention for obese pregnant women across Europe implemented as planned?:Process evaluation of the DALI study
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Jelsma, Judith G M, Simmons, David, Gobat, Nina, Rollnick, Stephen, Blumska, Kinga, Jans, Goele, Galjaard, Sander, Desoye, Gernot, Corcoy, Rosa, Juarez, Fabiola, Kautzky-Willer, Alexandra, Harreiter, Jürgen, van Assche, Andre, Devlieger, Roland, Timmerman, Dirk, Hill, David, Damm, Peter, Mathiesen, Elisabeth R, Wender-Ożegowska, Ewa, Zawiejska, Agnieszka, Lapolla, Annunziata, Dalfrà, Maria G, Del Prato, Stefano, Bertolotto, Alessandra, Dunne, Fidelma, Jensen, Dorte M, Andersen, Liselotte, Snoek, Frank J, van Poppel, Mireille N M, Jelsma, Judith G M, Simmons, David, Gobat, Nina, Rollnick, Stephen, Blumska, Kinga, Jans, Goele, Galjaard, Sander, Desoye, Gernot, Corcoy, Rosa, Juarez, Fabiola, Kautzky-Willer, Alexandra, Harreiter, Jürgen, van Assche, Andre, Devlieger, Roland, Timmerman, Dirk, Hill, David, Damm, Peter, Mathiesen, Elisabeth R, Wender-Ożegowska, Ewa, Zawiejska, Agnieszka, Lapolla, Annunziata, Dalfrà, Maria G, Del Prato, Stefano, Bertolotto, Alessandra, Dunne, Fidelma, Jensen, Dorte M, Andersen, Liselotte, Snoek, Frank J, and van Poppel, Mireille N M
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BACKGROUND: Process evaluation is an essential part of designing and assessing complex interventions. The vitamin D and lifestyle intervention study (DALI) study is testing different strategies to prevent development of gestational diabetes mellitus among European obese pregnant women with a body mass index ≥29 kg/m2. The intervention includes guidance on physical activity and/or healthy eating by a lifestyle coach trained in motivational interviewing (MI). The aim of this study was to assess the process elements: reach, dose delivered, fidelity and satisfaction and to investigate whether these process elements were associated with changes in gestational weight gain (GWG).METHODS: Data on reach, dose delivered, fidelity, and satisfaction among 144 participants were collected. Weekly recruitment reports, notes from meetings, coach logs and evaluation questionnaires (n = 110) were consulted. Fidelity of eight (out of twelve) lifestyle coach practitioners was assessed by analysing audio recorded counselling sessions using the MI treatment integrity scale. Furthermore, associations between process elements and GWG were assessed with linear regression analyses.RESULTS: A total of 20% of the possible study population (reach) was included in this analysis. On average 4.0 (of the intended 5) face-to-face sessions were delivered. Mean MI fidelity almost reached 'expert opinion' threshold for the global scores, but was below 'beginning proficiency' for the behavioural counts. High variability in quality of MI between practitioners was identified. Participants were highly satisfied with the intervention, the lifestyle coach and the intervention materials. No significant associations were found between process elements and GWG.CONCLUSION: Overall, the intervention was well delivered and received by the study population, but did not comply with all the principles of MI. Ensuring audio recording of lifestyle sessions throughout the study would facilitate p
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- 2017
12. Correlates of poor mental health in early pregnancy in obese European women
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Sattler, Matteo C, Jelsma, Judith G M, Bogaerts, Annick, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Adelantado, Juan M, Kautzky-Willer, Alexandra, Harreiter, Jürgen, van Assche, Frans A, Devlieger, Roland, Jans, Goele, Galjaard, Sander, Hill, David, Damm, Peter, Mathiesen, Elisabeth R, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Blumska, Kinga, Lapolla, Annunziata, Dalfrà, Maria G, Bertolotto, Alessandra, Dunne, Fidelma, Jensen, Dorte M, Andersen, Lise Lotte T, Snoek, Frank J, van Poppel, Mireille N M, Sattler, Matteo C, Jelsma, Judith G M, Bogaerts, Annick, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Adelantado, Juan M, Kautzky-Willer, Alexandra, Harreiter, Jürgen, van Assche, Frans A, Devlieger, Roland, Jans, Goele, Galjaard, Sander, Hill, David, Damm, Peter, Mathiesen, Elisabeth R, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Blumska, Kinga, Lapolla, Annunziata, Dalfrà, Maria G, Bertolotto, Alessandra, Dunne, Fidelma, Jensen, Dorte M, Andersen, Lise Lotte T, Snoek, Frank J, and van Poppel, Mireille N M
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BACKGROUND: Depression during pregnancy is associated with higher maternal morbidity and mortality, and subsequent possible adverse effects on the cognitive, emotional and behavioral development of the child. The aim of the study was to identify maternal characteristics associated with poor mental health, in a group of overweight/obese pregnant women in nine European countries, and thus, to contribute to better recognition and intervention for maternal depression.METHODS: In this cross-sectional observational study, baseline data from early pregnancy (< 20 weeks) of the DALI (Vitamin D and Lifestyle Intervention for gestational diabetes mellitus prevention) study were analyzed. Maternal mental health was assessed with the World Health Organization Well-Being Index (WHO-5). Women were classified as having a low (WHO-5 ≤ 50) or high wellbeing.RESULTS: A total of 735 pregnant women were included. The prevalence of having a low wellbeing was 27.2%, 95% CI [24.0, 30.4]. Multivariate analysis showed independent associations between low wellbeing and European ethnicity, OR = .44, 95% CI [.25, .77], shift work, OR = 1.81, 95% CI [1.11, 2.93], insufficient sleep, OR = 3.30, 95% CI [1.96, 5.55], self-efficacy, OR = .95, 95% CI [.92, .98], social support, OR = .94, 95% CI [.90, .99], and pregnancy-related worries (socioeconomic: OR = 1.08, 95% CI [1.02, 1.15]; health: OR = 1.06, 95% CI [1.01, 1.11]; relationship: OR = 1.17, 95% CI [1.05, 1.31]).CONCLUSIONS: Mental health problems are common in European overweight/obese pregnant women. The identified correlates might help in early recognition and subsequent treatment of poor mental health problems during pregnancy. This is important to reduce the unfavorable effects of poor mental health on pregnancy outcomes.TRIAL REGISTRATION: ISRCTN70595832 , 02.12.2011.
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- 2017
13. Epidemiology of gestational diabetes mellitus according to IADPSG/WHO 2013 criteria among obese pregnant women in Europe
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Egan, Aoife M, Vellinga, Akke, Harreiter, Jürgen, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Adelantado, Juan M, Devlieger, Roland, Van Assche, Andre, Galjaard, Sander, Damm, Peter, Mathiesen, Elisabeth R, Jensen, Dorte M, Andersen, Liselotte, Lapolla, Annuziata, Dalfrà, Maria G, Bertolotto, Alessandra, Mantaj, Urszula, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David, Jelsma, Judith G M, Snoek, Frank J, Worda, Christof, Bancher-Todesca, Dagmar, van Poppel, Mireille N M, Kautzky-Willer, Alexandra, Dunne, Fidelma P, Egan, Aoife M, Vellinga, Akke, Harreiter, Jürgen, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Adelantado, Juan M, Devlieger, Roland, Van Assche, Andre, Galjaard, Sander, Damm, Peter, Mathiesen, Elisabeth R, Jensen, Dorte M, Andersen, Liselotte, Lapolla, Annuziata, Dalfrà, Maria G, Bertolotto, Alessandra, Mantaj, Urszula, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David, Jelsma, Judith G M, Snoek, Frank J, Worda, Christof, Bancher-Todesca, Dagmar, van Poppel, Mireille N M, Kautzky-Willer, Alexandra, and Dunne, Fidelma P
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AIMS/HYPOTHESIS: Accurate prevalence estimates for gestational diabetes mellitus (GDM) among pregnant women in Europe are lacking owing to the use of a multitude of diagnostic criteria and screening strategies in both high-risk women and the general pregnant population. Our aims were to report important risk factors for GDM development and calculate the prevalence of GDM in a cohort of women with BMI ≥29 kg/m(2) across 11 centres in Europe using the International Association of the Diabetes and Pregnancy Study Groups (IADPSG)/WHO 2013 diagnostic criteria.METHODS: Pregnant women (n = 1023, 86.3% European ethnicity) with a BMI ≥29.0 kg/m(2) enrolled into the Vitamin D and Lifestyle Intervention for GDM Prevention (DALI) pilot, lifestyle and vitamin D studies of this pan-European multicentre trial, attended for an OGTT during pregnancy. Demographic, anthropometric and metabolic data were collected at enrolment and throughout pregnancy. GDM was diagnosed using IADPSG/WHO 2013 criteria. GDM treatment followed local policies.RESULTS: The number of women recruited per country ranged from 80 to 217, and the dropout rate was 7.1%. Overall, 39% of women developed GDM during pregnancy, with no significant differences in prevalence across countries. The prevalence of GDM was high (24%; 242/1023) in early pregnancy. Despite interventions used in the DALI study, a further 14% (94/672) had developed GDM when tested at mid gestation (24-28 weeks) and 13% (59/476) of the remaining cohort at late gestation (35-37 weeks). Demographics and lifestyle factors were similar at baseline between women with GDM and those who maintained normal glucose tolerance. Previous GDM (16.5% vs 7.9%, p = 0.002), congenital malformations (6.4% vs 3.3%, p = 0.045) and a baby with macrosomia (31.4% vs 17.9%, p = 0.001) were reported more frequently in those who developed GDM. Significant anthropometric and metabolic differences were already present in early pregnancy between women who deve
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- 2017
14. Beliefs, barriers and preferences of European overweight women to adopt a healthier lifestyle in pregnancy to minimize risk of developing gestational diabetes mellitus: an explorative study
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Jelsma, Judith G.M., van Leeuwen, Karen M., Oostdam, Nicolette, Bunn, Christopher, Simmons, David, Desoye, Gernot, Adelantado, Juan M., Kautzky-Willer, Alexandra, Harreiter, Jürgen, van Assche, Andre, Timmerman, Dirk, Hill, David, Damm, Peter, Mathiesen, Elisabeth R., Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Pablo, Rebollo, Lapolla, Annunziata, Dalfrà, Maria G., del Prato, Stefano, Bertolotto, Alessandra, Dunne, Fidelma, Jensen, Dorte M., Andersen, Liselotte, Snoek, Frank J., and van Poppel, Mireille N.M.
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RA0421 ,H1 ,HQ - Abstract
Introduction: Overweight and obese women are at high risk of developing gestational diabetes mellitus (GDM). Lifestyle programs might help curb the GDM risk. We explored beliefs, perceived barriers and preferences regarding lifestyle changes among overweight European pregnant women to help inform the development of future high quality lifestyle interventions.\ud \ud Methods: An explorative mixed methods, two-staged study was conducted to gather information from pregnant European women (BMI≥25kg/m2). In three European countries (Belgium, Netherlands, United Kingdom) interviews were conducted, followed by questionnaires in six other European countries (Austria, Denmark, Ireland, Italy, Poland, Spain). Content analysis, descriptive and chi square statistics were applied (p
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- 2016
15. Is a motivational interviewing based lifestyle intervention for obese pregnant women across Europe implemented as planned? Process evaluation of the DALI study
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Jelsma, Judith G. M., primary, Simmons, David, additional, Gobat, Nina, additional, Rollnick, Stephen, additional, Blumska, Kinga, additional, Jans, Goele, additional, Galjaard, Sander, additional, Desoye, Gernot, additional, Corcoy, Rosa, additional, Juarez, Fabiola, additional, Kautzky-Willer, Alexandra, additional, Harreiter, Jürgen, additional, van Assche, Andre, additional, Devlieger, Roland, additional, Timmerman, Dirk, additional, Hill, David, additional, Damm, Peter, additional, Mathiesen, Elisabeth R., additional, Wender-Ożegowska, Ewa, additional, Zawiejska, Agnieszka, additional, Lapolla, Annunziata, additional, Dalfrà, Maria G., additional, del Prato, Stefano, additional, Bertolotto, Alessandra, additional, Dunne, Fidelma, additional, Jensen, Dorte M., additional, Andersen, Liselotte, additional, Snoek, Frank J., additional, and van Poppel, Mireille N. M., additional
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- 2017
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16. Effect of physical activity and/or healthy eating on GDM risk: The DALI Lifestyle Study
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Simmons, David, primary, Devlieger, Roland, additional, van Assche, André, additional, Jans, Goele, additional, Galjaard, Sander, additional, Corcoy, Rosa, additional, Adelantado, Juan M, additional, Dunne, Fidelma, additional, Desoye, Gernot, additional, Harreiter, Jürgen, additional, Kautzky-Willer, Alexandra, additional, Damm, Peter, additional, Mathiesen, Elisabeth R, additional, Jensen, Dorte M, additional, Andersen, Liselotte, additional, Lapolla, Annunziata, additional, Dalfrà, Maria G, additional, Bertolotto, Alessandra, additional, Wender-Ozegowska, Ewa, additional, Zawiejska, Agnieszka, additional, Hill, David, additional, Snoek, Frank J, additional, Jelsma, Judith GM, additional, and van Poppel, Mireille NM, additional
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- 2016
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17. IADPSG and WHO 2013 gestational diabetes mellitus criteria identify obese women with marked insulin resistance in early pregnancy
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Harreiter, Jurgen, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Adelantado, Juan M, Devlieger, Roland, van Assche, Andre, Galjaard, Sander, Damm, Peter, Mathiesen, Elisabeth R., Jensen, Dorte M., Andersen, Lise Lotte Torvin, Dunne, Fidelma, Lapolla, Annunziata, Dalfrà, Maria G, Bertolotto, Alessandra, Mantaj, Urzula, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David, Jelsma, Judith G M, Snoek, Frank J, Worda, Christof, Bancher-Todesca, Dagmar, van Poppel, Mireille N M, Kautzky-Willer, Alexandra, Harreiter, Jurgen, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Adelantado, Juan M, Devlieger, Roland, van Assche, Andre, Galjaard, Sander, Damm, Peter, Mathiesen, Elisabeth R., Jensen, Dorte M., Andersen, Lise Lotte Torvin, Dunne, Fidelma, Lapolla, Annunziata, Dalfrà, Maria G, Bertolotto, Alessandra, Mantaj, Urzula, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David, Jelsma, Judith G M, Snoek, Frank J, Worda, Christof, Bancher-Todesca, Dagmar, van Poppel, Mireille N M, and Kautzky-Willer, Alexandra
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- 2016
18. Beliefs, Barriers, and Preferences of European Overweight Women to Adopt a Healthier Lifestyle in Pregnancy to Minimize Risk of Developing Gestational Diabetes Mellitus:An Explorative Study
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Jelsma, Judith G M, Van Leeuwen, Karen M., Oostdam, Nicolette, Bunn, Christopher, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Adelantado, Juan M, Kautzky-Willer, Alexandra, Harreiter, Jurgen, Van Assche, Frans Andre, Devlieger, Roland, Timmerman, Dirk, Hill, David, Damm, Peter, Mathiesen, Elisabeth R., Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Rebollo, Pablo, Lapolla, Annunziata, Dalfrà, Maria G, Del Prato, Stefano, Bertolotto, Alessandra, Dunne, Fidelma, Jensen, Dorte M., Andersen, Lise Lotte Torvin, Snoek, Frank J, van Poppel, Mireille N M, Jelsma, Judith G M, Van Leeuwen, Karen M., Oostdam, Nicolette, Bunn, Christopher, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Adelantado, Juan M, Kautzky-Willer, Alexandra, Harreiter, Jurgen, Van Assche, Frans Andre, Devlieger, Roland, Timmerman, Dirk, Hill, David, Damm, Peter, Mathiesen, Elisabeth R., Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Rebollo, Pablo, Lapolla, Annunziata, Dalfrà, Maria G, Del Prato, Stefano, Bertolotto, Alessandra, Dunne, Fidelma, Jensen, Dorte M., Andersen, Lise Lotte Torvin, Snoek, Frank J, and van Poppel, Mireille N M
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Introduction. We explored beliefs, perceived barriers, and preferences regarding lifestyle changes among overweight European pregnant women to help inform the development of future lifestyle interventions in the prevention of gestational diabetes mellitus. Methods. An explorative mixed methods, two-staged study was conducted to gather information from pregnant European women (BMI ≥ 25 kg/m2). In three European countries 21 interviews were conducted, followed by 71 questionnaires in six other European countries. Content analysis and descriptive and chi-square statistics were applied (p < 0.05). Results. Women preferred to obtain detailed information about their personal risk. The health of their baby was a major motivating factor. Perceived barriers for physical activity included pregnancy-specific issues such as tiredness and experiencing physical complaints. Insufficient time was a barrier more frequently reported by women with children. Abstaining from snacking was identified as a challenge for the majority of women, especially for those without children. Women preferred to obtain support from their partner, as well as health professionals and valued flexible lifestyle programs. Conclusions. Healthcare professionals need to inform overweight pregnant women about their personal risk, discuss lifestyle modification, and assist in weight management. Lifestyle programs should be tailored to the individual, taking into account barriers experienced by overweight first-time mothers and multipara women.
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- 2016
19. Physical activity, depressed mood and pregnancy worries in European obese pregnant women:results from the DALI study
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de Wit, Linda, Jelsma, Judith G M, van Poppel, Mireille N M, Bogaerts, Annick, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Kautzky-Willer, Alexandra, Harreiter, Jürgen, van Assche, Andre, Devlieger, Roland, Timmerman, Dirk, Hill, David, Damm, Peter, Mathiesen, Elisabeth R, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Rebollo, Pablo, Lapolla, Annunziata, Dalfrà, Maria G, Del Prato, Stefano, Bertolotto, Alessandra, Dunne, Fidelma, Jensen, Dorte M, Andersen, Liselotte, Snoek, Frank J, de Wit, Linda, Jelsma, Judith G M, van Poppel, Mireille N M, Bogaerts, Annick, Simmons, David, Desoye, Gernot, Corcoy, Rosa, Kautzky-Willer, Alexandra, Harreiter, Jürgen, van Assche, Andre, Devlieger, Roland, Timmerman, Dirk, Hill, David, Damm, Peter, Mathiesen, Elisabeth R, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Rebollo, Pablo, Lapolla, Annunziata, Dalfrà, Maria G, Del Prato, Stefano, Bertolotto, Alessandra, Dunne, Fidelma, Jensen, Dorte M, Andersen, Liselotte, and Snoek, Frank J
- Abstract
BACKGROUND: The purpose of this study was to examine the association between mental health status (i.e. depressed mood and pregnancy-related worries) and objectively measured physical activity levels in obese pregnant women from seven European countries.METHODS: Baseline data from the vitamin D and lifestyle intervention for the prevention of gestational diabetes mellitus (DALI) study were used. Time spent in moderate-to-vigorous physical activity (MVPA) and sedentary behaviour was measured with accelerometers. Depressed mood was measured with the WHO well-being index (WHO-5) and pregnancy-related worries with the Cambridge Worry Scale (CWS). In addition, socio-demographic characteristics, lifestyle factors, and perceptions and attitude regarding weight management and physical activity were measured. Linear regression analyses were performed to assess the association of mental health status with MVPA and sedentary behaviour.RESULTS: A total of 98 obese pregnant women from Austria, Belgium, Ireland, Italy, Poland, Spain and the Netherlands were included. Women had a mean age of 31.6 ± 5.8 years, a pre-pregnancy BMI of 34.1 ± 4.3 kg/m(2), and were on average 15.4 ± 2.8 weeks pregnant. WHO-5 scores indicative of depressed mood (<50) were reported by 27.1 % of the women and most frequently endorsed pregnancy-related worries pertained to own and the baby's health. Women with good well-being spent 85% more time in MVPA compared to women with a depressed mood (P = 0.03). No differences in MVPA levels were found for women with no, some, or many pregnancy worries. Depressed mood and pregnancy-related worries were not associated with sedentary behaviour.CONCLUSIONS: These findings suggest that in pregnant women who are obese, a depressed mood, but not pregnancy-related worries, may be associated with less physical activity. The combined risk of poor mental health and low physical activity levels makes women vulnerable for pregnancy complications. Wh
- Published
- 2015
20. Physical activity, depressed mood and pregnancy worries in European obese pregnant women: results from the DALI study
- Author
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de Wit, Linda, primary, Jelsma, Judith G. M., additional, van Poppel, Mireille N. M., additional, Bogaerts, Annick, additional, Simmons, David, additional, Desoye, Gernot, additional, Corcoy, Rosa, additional, Kautzky-Willer, Alexandra, additional, Harreiter, Jürgen, additional, van Assche, Andre, additional, Devlieger, Roland, additional, Timmerman, Dirk, additional, Hill, David, additional, Damm, Peter, additional, Mathiesen, Elisabeth R., additional, Wender-Ozegowska, Ewa, additional, Zawiejska, Agnieszka, additional, Rebollo, Pablo, additional, Lapolla, Annunziata, additional, Dalfrà, Maria G., additional, Del Prato, Stefano, additional, Bertolotto, Alessandra, additional, Dunne, Fidelma, additional, Jensen, Dorte M., additional, Andersen, Liselotte, additional, and Snoek, Frank J., additional
- Published
- 2015
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21. Effect of Physical Activity and/or Healthy Eating on GDM Risk: The DALI Lifestyle Study.
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Simmons, David, Devlieger, Roland, van Assche, André, Jans, Goele, Galjaard, Sander, Corcoy, Rosa, Adelantado, Juan M, Dunne, Fidelma, Desoye, Gernot, Harreiter, Jürgen, Kautzky-Willer, Alexandra, Damm, Peter, Mathiesen, Elisabeth R, Jensen, Dorte M, Andersen, Liselotte, Lapolla, Annunziata, Dalfrà, Maria G, Bertolotto, Alessandra, Wender-Ozegowska, Ewa, Zawiejska, Agnieszka, Hill, David, Snoek, Frank J, Jelsma, Judith G M, and van Poppel, Mireille N M
- Abstract
Lifestyle approaches for preventing gestational diabetes mellitus (GDM) have produced mixed results.
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- 2017
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22. Reference Intervals for Hemoglobin A1c in Pregnant Women: Data from an Italian Multicenter Study
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Mosca, Andrea, primary, Paleari, Renata, primary, Dalfrà, Maria G, primary, Di Cianni, Graziano, primary, Cuccuru, Ilaria, primary, Pellegrini, Giovanni, primary, Malloggi, Lucia, primary, Bonomo, Matteo, primary, Granata, Simona, primary, Ceriotti, Ferruccio, primary, Castiglioni, Maria T, primary, Songini, Marco, primary, Tocco, Giuliana, primary, Masin, Michela, primary, Plebani, Mario, primary, and Lapolla, Annunziata, primary
- Published
- 2006
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23. Epidemiology of gestational diabetes mellitus according to IADPSG/WHO 2013 criteria among obese pregnant women in Europe.
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Egan AM, Vellinga A, Harreiter J, Simmons D, Desoye G, Corcoy R, Adelantado JM, Devlieger R, Van Assche A, Galjaard S, Damm P, Mathiesen ER, Jensen DM, Andersen L, Lapolla A, Dalfrà MG, Bertolotto A, Mantaj U, Wender-Ozegowska E, Zawiejska A, Hill D, Jelsma JGM, Snoek FJ, Worda C, Bancher-Todesca D, van Poppel MNM, Kautzky-Willer A, and Dunne FP
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- Adult, Comorbidity, Europe epidemiology, Female, Humans, Pregnancy, Prevalence, Young Adult, Diabetes, Gestational epidemiology, Obesity epidemiology
- Abstract
Aims/hypothesis: Accurate prevalence estimates for gestational diabetes mellitus (GDM) among pregnant women in Europe are lacking owing to the use of a multitude of diagnostic criteria and screening strategies in both high-risk women and the general pregnant population. Our aims were to report important risk factors for GDM development and calculate the prevalence of GDM in a cohort of women with BMI ≥29 kg/m
2 across 11 centres in Europe using the International Association of the Diabetes and Pregnancy Study Groups (IADPSG)/WHO 2013 diagnostic criteria., Methods: Pregnant women (n = 1023, 86.3% European ethnicity) with a BMI ≥29.0 kg/m2 enrolled into the Vitamin D and Lifestyle Intervention for GDM Prevention (DALI) pilot, lifestyle and vitamin D studies of this pan-European multicentre trial, attended for an OGTT during pregnancy. Demographic, anthropometric and metabolic data were collected at enrolment and throughout pregnancy. GDM was diagnosed using IADPSG/WHO 2013 criteria. GDM treatment followed local policies., Results: The number of women recruited per country ranged from 80 to 217, and the dropout rate was 7.1%. Overall, 39% of women developed GDM during pregnancy, with no significant differences in prevalence across countries. The prevalence of GDM was high (24%; 242/1023) in early pregnancy. Despite interventions used in the DALI study, a further 14% (94/672) had developed GDM when tested at mid gestation (24-28 weeks) and 13% (59/476) of the remaining cohort at late gestation (35-37 weeks). Demographics and lifestyle factors were similar at baseline between women with GDM and those who maintained normal glucose tolerance. Previous GDM (16.5% vs 7.9%, p = 0.002), congenital malformations (6.4% vs 3.3%, p = 0.045) and a baby with macrosomia (31.4% vs 17.9%, p = 0.001) were reported more frequently in those who developed GDM. Significant anthropometric and metabolic differences were already present in early pregnancy between women who developed GDM and those who did not., Conclusions/interpretation: The prevalence of GDM diagnosed by the IADPSG/WHO 2013 GDM criteria in European pregnant women with a BMI ≥29.0 kg/m2 is substantial, and poses a significant health burden to these pregnancies and to the future health of the mother and her offspring. Uniform criteria for GDM diagnosis, supported by robust evidence for the benefits of treatment, are urgently needed to guide modern GDM screening and treatment strategies.- Published
- 2017
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24. Beliefs, Barriers, and Preferences of European Overweight Women to Adopt a Healthier Lifestyle in Pregnancy to Minimize Risk of Developing Gestational Diabetes Mellitus: An Explorative Study.
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Jelsma JG, van Leeuwen KM, Oostdam N, Bunn C, Simmons D, Desoye G, Corcoy R, Adelantado JM, Kautzky-Willer A, Harreiter J, van Assche FA, Devlieger R, Timmerman D, Hill D, Damm P, Mathiesen ER, Wender-Ozegowska E, Zawiejska A, Rebollo P, Lapolla A, Dalfrà MG, Del Prato S, Bertolotto A, Dunne F, Jensen DM, Andersen LL, Snoek FJ, and van Poppel MN
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- Adult, Diabetes, Gestational prevention & control, Diet Therapy psychology, Europe, Exercise psychology, Female, Humans, Obesity therapy, Overweight psychology, Overweight therapy, Pregnancy, Qualitative Research, Surveys and Questionnaires, Attitude to Health, Diabetes, Gestational psychology, Healthy Lifestyle, Obesity psychology, Patient Preference, Pregnancy Complications psychology, Risk Reduction Behavior
- Abstract
Introduction: We explored beliefs, perceived barriers, and preferences regarding lifestyle changes among overweight European pregnant women to help inform the development of future lifestyle interventions in the prevention of gestational diabetes mellitus., Methods: An explorative mixed methods, two-staged study was conducted to gather information from pregnant European women (BMI ≥ 25 kg/m2). In three European countries 21 interviews were conducted, followed by 71 questionnaires in six other European countries. Content analysis and descriptive and chi-square statistics were applied (p < 0.05)., Results: Women preferred to obtain detailed information about their personal risk. The health of their baby was a major motivating factor. Perceived barriers for physical activity included pregnancy-specific issues such as tiredness and experiencing physical complaints. Insufficient time was a barrier more frequently reported by women with children. Abstaining from snacking was identified as a challenge for the majority of women, especially for those without children. Women preferred to obtain support from their partner, as well as health professionals and valued flexible lifestyle programs., Conclusions: Healthcare professionals need to inform overweight pregnant women about their personal risk, discuss lifestyle modification, and assist in weight management. Lifestyle programs should be tailored to the individual, taking into account barriers experienced by overweight first-time mothers and multipara women.
- Published
- 2016
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