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7. Soviet and German advisors put doctrine to the test: Tanks in the siege of Madrid, pt 2

Author

Daley, John L.S.

Subjects
SPAIN - History, MILITARY HISTORY - Spain, ARMORED WARFARE - History
Abstract

illus bibliog, Part 1: The theory and practice of armored warfare in Spain--October 1936-February 1937. v108 no 2 (Mar-Apr 1999): p30+; part 2: Soviet and German advisors put doctrine to the test: Tanks in the siege of Madrid. v108 no 3 (May-Jun 1999): p33-37

Published
1999

9. The theory and practice of armored warfare in Spain--October 1936-February 1937, pt 1

Author

Daley, John L.S.

Subjects
SPAIN - History, MILITARY HISTORY - Spain, ARMORED WARFARE - History
Abstract

illus bibliog, Part 1: The theory and practice of armored warfare in Spain--October 1936-February 1937. v108 no 2 (Mar-Apr 1999): p30+; part 2: Soviet and German advisors put doctrine to the test: Tanks in the siege of Madrid. v108 no 3 (May-Jun 1999): p33-37

Published
1999

11. Exploring the Contribution of Play to Social Capital in Institutional Adult Learning Settings

Author

Harris, Pauline and Daley, John

Abstract

This paper explores how play as an educational tool can enhance social capital for adult learners in institutional settings. Framed by conceptualisations of social capital (Putnam 1993, 2000) and play (Melamed 1987, Meares 2005, Vygotsky 1978) and supported by research literature on play in adult learning, our action research in our adult education classes focuses on cooperative forms of play in which pretend, role-play, improvisation, playful activities and a playful mindset were key components. We investigate these play experiences in terms of their implications for nurturing adult learners' social capital. Our preliminary findings to date reveal that play contributes to social capital by enriching adult learners' engagement, cooperation and sense of connectedness with one another as well as with people, resources and information beyond their group. (Contains 2 figures.)

Published
2008

15. Fort Dudley: Doing Public History Before Public History was Cool

Author

Daley, John

Subjects
Fort Scott, Kansas -- History, Humanities
Abstract

As noted on previous pages, Dudley Taylor Cornish contributed much to our institution during his 35-year career here in Pittsburg. And true to the self-effacing persona so many remember, he [...]

Published
2018

16. The bases for the authority of the Australian Constitution

Author

Daley, John C. and John, Finnis

Subjects
340, Legal philosophy, Philosophy of law, Ethics and philosophy of law, Constitutional & administrative law, Australia, Constitution, authority, popular sovereignty
Abstract

What are the possible bases for the authority of the Australian Constitution? Why should people and judges ever obey the text of the Constitution? The developing tools of analytical jurisprudence assist in answering these questions. Despite its currency, the concept of "sovereignty" provides little assistance in understanding how law provides reasons for action. The concept of authority is more useful. The text of the Australian Constitution has authority in that it provides presumptive reasons for action, overruled when they appear sufficiently erroneous on a cursory examination. The Constitution is part of the Australian legal system. A legal system is normally identified partly by moral norms. These moral norms themselves require that legal systems also be identified where possible by reference to the directives of a previous de facto authority - even when that previous authority no longer has power to make new legal norms. A legal system will be "legitimate" if any improvement to be achieved by revolution would be outweighed by the uncertainty revolution creates. Against this theoretical background, various theories about the Constitution's authority can be assessed. Although the enactment of the Constitution by the Imperial Parliament provides the Constitution with legal authority, it does not confer moral legitimacy. Contrary to a growing judicial and academic consensus in Australia, the Constitution's legitimate authority is not derived from the "will of the people". Nor is it derived from the Constitution's Founders. The will of the people cannot be identified reliably, and wound not provide sufficient reasons for action. The Constitution does embody a federal compact between the colonies. Because it is worthwhile to keep political promises, the polities of the States should fulfil this compact, even though the compact only imposes weak obligations on the Commonwealth. Other possible bases for the Constitution's authority are also inadequate. These include claims that judges are bound to apply the Constitution because their authority is based upon it; that the Constitution embodies "associate obligations", and that the Constitution isa commitment to protect individual rights and democracy. Instead the Constitution has legitimate authority principally because it coordinates individual action towards desirable goals. The Australian Constitution settles the location of authority by authority.

Published
1999

17. Vaccination with Irradiated Autologous Melanoma Cells Engineered to Secrete Human Granulocyte--Macrophage Colony-Stimulating Factor Generates Potent Antitumor Immunity in Patients with Metastatic Melanoma

Author

Soiffer, Robert, Lynch, Thomas, Mihm, Martin, Jung, Ken, Rhuda, Catherine, Schmollinger, Jan C., Hodi, F. Stephen, Liebster, Laura, Lam, Prudence, Mentzer, Steven, Singer, Samuel, Tanabe, Kenneth K., Cosimi, A. Benedict, Duda, Rosemary, Sober, Arthur, Bhan, Atul, Daley, John, Neuberg, Donna, Parry, Gordon, Rokovich, Joseph, Richards, Laurie, Drayer, Jan, Berns, Anton, Clift, Shirley, Cohen, Lawrence K., Mulligan, Richard C., and Dranoff, Glenn

Published
1998

19. Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

Author

Reitman, Zachary J., Paolella, Brenton R., Bergthold, Guillaume, Pelton, Kristine, Becker, Sarah, Jones, Robert, Sinai, Claire E., Malkin, Hayley, Huang, Ying, Grimmet, Leslie, Herbert, Zachary T., Sun, Yu, Weatherbee, Jessica L., Alberta, John A., Daley, John F., Rozenblatt-Rosen, Orit, Condurat, Alexandra L., Qian, Kenin, Khadka, Prasidda, Segal, Rosalind A., Haas-Kogan, Daphne, Filbin, Mariella G., Suva, Mario L., Regev, Aviv, Stiles, Charles D., Kieran, Mark W., Goumnerova, Liliana, Ligon, Keith L., Shalek, Alex K., Bandopadhayay, Pratiti, and Beroukhim, Rameen

Published
2019
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27. The Episode of Purposive Change: Field Testing a Practice Model.

Author

Daley, John Michael

Abstract

The Episode of Purposive Change Model was used to evaluate the statewide redesign of human services for vulnerable children/families. Significant findings included the following: (1) community context is important; (2) long-term change requires keeping the initiative on the community agenda; and (3) participants must remain focused on ultimate results sought from the change. (SK)

Published
1997

32. Understanding the Dynamics of Diversity within Nonprofit Boards.

Author

Daley, John Michael and Angulo, Julio

Abstract

A model of diversity in nonprofit boards has these elements: use of language to further interests, levels of civic participation, social exchanges and incentives, socialization and acculturation of board members, and board composition and representation. Attention to these elements can foster inclusive, functionally diverse boards. (SK)

Published
1994

35. People-Centered Community Planning.

Author

Daley, John Michael and Angulo, Julio

Abstract

Criticisms of rational synoptic planning are that it is elitist, simplistic, and supportive of existing power relationships. An alternative, people-centered community planning, views the population to be studied as ideological and historical beings, uses knowledge of and by the people as a base, requires interpersonal as well as analytical skills, and unites participatory planning with population-specific planning. (SK)

Published
1990

46. Antileukemic effects of the novel, mutant FLT3 inhibitor NVP-AST487: effects on PKC412-sensitive and -resistant FLT3-expressing cells

Author

Weisberg, Ellen, Roesel, Johannes, Bold, Guido, Furet, Pascal, Jiang, Jingrui, Cools, Jan, Wright, Renee D., Nelson, Erik, Barrett, Rosemary, Ray, Arghya, Moreno, Daisy, Hall-Meyers, Elizabeth, Stone, Richard, Galinsky, Ilene, Fox, Edward, Gilliland, Gary, Daley, John F., Lazo-Kallanian, Suzan, Kung, Andrew L., and Griffin, James D.

Published
2008
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48. The extension of an ocean carrier's limitation of liability to the inland carriage of goods under a through ocean bill of lading: how the Second and Eleventh Circuits have undone the work of the Supreme Court in Kirby.

Author

Daley, John M.

Subjects
Bills of lading -- Laws, regulations and rules, Limited liability -- Laws, regulations and rules, Shipping industry -- Laws, regulations and rules, Altadis USA, Inc. ex rel. Fireman's Fund Insurance Co. v. Sea Star Line L.L.C. (458 F.3d 1288 (11th Cir. 2006)), Norfolk Southern Railway v. James N. Kirby Pty. (543 U.S. 14 (2004)), Sompo Japan Insurance Co. of America v. Union Pacific Railroad (456 F.3d 54 (2d Cir. 2006)), Government regulation
Published
2008

49. Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

Author

Massachusetts Institute of Technology. Institute for Medical Engineering & Science, Massachusetts Institute of Technology. Department of Chemistry, Broad Institute of MIT and Harvard, Koch Institute for Integrative Cancer Research at MIT, Reitman, Zachary J., Paolella, Brenton R., Bergthold, Guillaume, Pelton, Kristine, Becker, Sarah, Jones, Robert, Sinai, Claire E., Malkin, Hayley, Huang, Ying, Grimmet, Leslie, Herbert, Zachary T., Sun, Yu, Weatherbee, Jessica L., Alberta, John A., Daley, John F., Rozenblatt-Rosen, Orit, Condurat, Alexandra L., Qian, Kenin, Khadka, Prasidda, Segal, Rosalind A., Haas-Kogan, Daphne, Filbin, Mariella G., Suva, Mario L., Regev, Aviv, Stiles, Charles D., Kieran, Mark W., Goumnerova, Liliana, Ligon, Keith L., Shalek, Alexander K, Bandopadhayay, Pratiti, Beroukhim, Rameen, Massachusetts Institute of Technology. Institute for Medical Engineering & Science, Massachusetts Institute of Technology. Department of Chemistry, Broad Institute of MIT and Harvard, Koch Institute for Integrative Cancer Research at MIT, Reitman, Zachary J., Paolella, Brenton R., Bergthold, Guillaume, Pelton, Kristine, Becker, Sarah, Jones, Robert, Sinai, Claire E., Malkin, Hayley, Huang, Ying, Grimmet, Leslie, Herbert, Zachary T., Sun, Yu, Weatherbee, Jessica L., Alberta, John A., Daley, John F., Rozenblatt-Rosen, Orit, Condurat, Alexandra L., Qian, Kenin, Khadka, Prasidda, Segal, Rosalind A., Haas-Kogan, Daphne, Filbin, Mariella G., Suva, Mario L., Regev, Aviv, Stiles, Charles D., Kieran, Mark W., Goumnerova, Liliana, Ligon, Keith L., Shalek, Alexander K, Bandopadhayay, Pratiti, and Beroukhim, Rameen

Abstract

Pilocytic astrocytoma (PA), the most common childhood brain tumor, is a low-grade glioma with a single driver BRAF rearrangement. Here, we perform scRNAseq in six PAs using methods that enabled detection of the rearrangement. When compared to higher-grade gliomas, a strikingly higher proportion of the PA cancer cells exhibit a differentiated, astrocyte-like phenotype. A smaller proportion of cells exhibit a progenitor-like phenotype with evidence of proliferation. These express a mitogen-activated protein kinase (MAPK) programme that was absent from higher-grade gliomas. Immune cells, especially microglia, comprise 40% of all cells in the PAs and account for differences in bulk expression profiles between tumor locations and subtypes. These data indicate that MAPK signaling is restricted to relatively undifferentiated cancer cells in PA, with implications for investigational therapies directed at this pathway.

Published
2020

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