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Two previously undescribed compounds, namely dalpulapans F and G (1 and 2), along with 11 known compounds were isolated from the MeOH crude extract of the roots of Dalbergia stipulacea. Dalpulapan F was found as a rare isoflavone-quinone derivative. Their structures and absolute configurations were supported by extensive spectroscopic data analysis, including 1 D and 2 D NMR, HRESIMS data, specific rotation data, and comparison of the experimental and calculated ECD data. Cytotoxicity evaluation of the isolated compounds against HepG2 and KKU-M156 cell lines revealed that isoflavonoid 9 and rotenoid 13 exhibited the most activity against the two cell lines. [ABSTRACT FROM AUTHOR]

Two new compounds, dalpulanone (1) and 2-hydroxyisomucronustyrene (2), were isolated from the stems of Dalbergia stipulacea. Fourteen known compounds (3–16) were also isolated. The chemical structures of all isolated compounds were elucidated using spectroscopic methods, including 1D-NMR, 2D-NMR, MS and IR data. Compound 4 displayed the strongest antifungal activity against Pythium insidiosum and had higher activity than the amphotericin-B standard. [ABSTRACT FROM AUTHOR]

The present paper reports the survey conducted from June 2012-December 2016 to assess the wild species used in oral hygiene and related dental recipes by four indigenous communities (Meitei, Maring, Kabui, Tangkhul) of Manipur, India. The age long tradition of blackening of teeth called Ha-sang practiced by the Maring tribe is documented for the first time. It was revealed that Dalbergia stipulacea Roxb. is exclusively used for the purpose. Additional notes on nine more species used in oral care are also highlighted. A total of 200 informants were interviewed for the purpose. Preference ranking calculation was employed for data analysis to assess the best choice of species used in dental hygiene for the respective four communities. The preference score for each species is different and highest preference of species for the respective communities are A. paniculata (35) for Meitei, D. stipulacea (36) for Maring, O. aristatus (32) for Kabui and M. malabathricum (31) for Tangkhul. The study concludes that D. stipulacea is a new addition to the plant list used in dental hygiene. It further emphasizes on their scientific exploitation and sustainable utilization in dental medicines. [ABSTRACT FROM AUTHOR]