1. Outcomes of trabeculectomy in juvenile open angle glaucoma
- Author
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Daizy Pathania, Sirisha Senthil, Harsha L Rao, Anil K Mandal, and Chandra Sekhar Garudadari
- Subjects
Blindness ,cataract ,eye lens ,risk factors ,treatment of cataract ,Low vision care ,multiple disabilities and visual impairment ,reading performance ,Accommodation ,presbyopia ,supraciliary segment implants ,Amblyopia ,citicoline ,patching ,Corneal endothelium ,human corneal endothelial precursor cells ,in vitro expansion ,sphere forming assay ,thermo-reversible gelation polymer ,transportation ,Endophthalmitis ,explantation ,fungal ,intraocular lens ,postoperative ,recurrent ,Colour perception ,learning disabilities ,school children ,stereo acuity ,testability ,visual acuity ,Contracted socket ,dermis fat graft ,porous orbital implant ,reconstruction ,Glucose ,in vitro anticataract ,lens ,Moringa oliefera ,′BARC I-125 Ocu-Prosta seeds′ ,choroidal melanoma ,ciliary body melanoma ,Episcleral plaque brachytherapy ,retinal angioma ,retinoblastoma ,vasoproliferative tumor ,Congenital glaucoma ,gonioscopy ,Retcam ,Acoustic features ,A-scan ,B-scan ,choroidal mass ,ultrasound biomicroscopy ,Cataract surgery ,education ,informed consent ,multimedia ,rural health ,Lagophthalmos ,silicone sling ,temporalis muscle ,Contrast sensitivity function ,disability ,function peak ,multiple sclerosis ,spatial frequency ,Congenital cataract ,developmental cataract ,outcome ,vision function ,Bacterial ,extracellular enzymes ,keratitis ,toxins ,Exotropic Duane retraction syndrome ,periosteal fixation ,strabismus surgery ,vertical rectus transposition ,Descemet′s stripping endothelial keratoplasty ,complications ,donor dislocation ,endothelial cell loss ,graft failure ,management ,Glaucoma ,glaucoma experimental ,parapapillary atrophy ,Juvenile open angle glaucoma ,juvenile glaucoma ,primary trabeculectomy ,trabeculectomy in young ,Ophthalmology ,RE1-994 - Abstract
Purpose: This study was aimed at reporting the outcomes of trabeculectomy in primary juvenile open angle glaucoma (JOAG). Design: This study was a retrospective noncomparative case series. Materials and Methods: We included 60 eyes of 41 JOAG patients who underwent primary trabeculectomy without mitomycin-C (MMC) between 1995 and 2007. The primary outcome was success, defined as complete, if intraocular pressure (IOP) was >5 and ≤21 mmHg without medications or qualified if IOP was >5 and ≤21 mmHg with or without antiglaucoma medications. Secondary outcome measures were mean and percentage IOP reduction, complications, and risk factors for the failure of trabeculectomy. Results: The mean (±standard deviation) age at presentation was 24.1 ± 6.8 years (range, 12-35). Mean follow-up was 67 ± 41 months (range, 12-156). At 1 year, the probability of complete success was 92% (n = 56, 95% CI: 81-96%), at 3 years it was 89% (n = 47, 95% CI: 78-95%), and at the end of 5 years, it was 80% (n = 34, 95% CI: 65-89%). The probability of qualified success was 100% (n = 60) at 1 year, 98% (n = 51, 95% CI: 87-100%) at 3 years, and 96% (n = 36, 95% CI: 84-99%) at the end of 5 years. The mean IOP reduced from 35 ± 10 to 13 ± 2.5 mmHg (P < 0.001) after trabeculectomy. There was no serious postoperative complication. Young age was the only significant risk factor associated with the failure (odds ratio = 0.89, P = 0.03). Conclusion: Primary trabeculectomy without MMC has good success rates in JOAG.
- Published
- 2014
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