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Aditya K Gupta,1,2 Deanne Daigle2 1Department of Medicine, University of Toronto School of Medicine, Toronto, 2Dermatology, Mediprobe Research Inc., London, ON, Canada Abstract: Luliconazole is a novel imidazole derivative, which has demonstrated in vitro efficacy against dermatophytes and Candida. The results from Phase III trials show that luliconazole 1% cream applied once daily for 2 weeks successfully resolved the clinical signs and symptoms as well as eradicated the pathologic fungi, which cause tinea pedis. A 1-week treatment with luliconazole 1% cream also produced favorable clinical and mycological results in clinical trials for tinea corporis and tinea cruris. Across trials, adverse events consisted mainly of localized reactions following application. The development of a new antifungal agent is timely due to mounting resistance among existing treatments. Because luliconazole requires a short duration of treatment, it may assist in reducing disease recurrence as a result of patient nonadherence. Keywords: antifungal, dermatophyte, athlete's foot, tinea cruris, tinea corporis, imidazole

This study aims at investigating syllabic processes in deaf readers (n=35) who were compared to readers of French as a second language (n=23) and to expert readers (n=40). Two experimental tasks varying in their degree of phonological awareness were created: one awareness– task and one awareness+ task. Results show that all participants have knowledge related to some syllabic structures of written French. However, that knowledge is more evident in the awareness– task than in the awareness+ task. The difference between results on both tasks is greater in the deaf group than in second-language readers or the expert readers. These results are discussed in terms of complementarity of syllabic processes in reading and in relation to the status of French for deaf readers. [ABSTRACT FROM AUTHOR]

Using two different methods -- bar and community household sampling -- 159 Latino gay men were recruited in the city of Tucson, Arizona. In addition to demographics, the study questionnaire assessed participants' sexual activity during the last 30 days with primary and nonprimary partners, condom use in the last year, and eight psychosocial constructs that have been predictive of HIV risk in different studies of (mostly white) gay/bisexual men. Questionnaires were available only in English; this Latino sample is thus likely to overrepresent highly acculturated, English-speaking men. Results show that 22% of the sample engaged in unprotected anal intercourse with nonmonogamous partners during the last 30 days; 51% of the sample reported at least one instance of unprotected anal intercourse during the last year. Of those men who practiced any anal intercourse during the last 30 days, 67% practiced unprotected anal intercourse with primary partners and 44% practiced unprotected intercourse with casual partners. Thus, the majority of Latino gay men who practiced anal intercourse in the month prior to the interview were not using condoms. Men who practiced unprotected intercourse with nonmonogamous partners reported lower annual incomes and were less educated. Two cognitive variables (behavioral intentions and perceptions of self-efficacy and self-control) and two behavioral variables (sex under the influence of alcohol and/or drugs and sex in public environments) emerged as the most important correlates of HIV risk. [ABSTRACT FROM AUTHOR]