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Your search keyword '"Dai, Ronghua"' showing total 178 results
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178 results on '"Dai, Ronghua"'

9. Reasons and Countermeasures for the Runaway Fault of the Large Flat-headed Tower Crane Rotation

Author

Wang Jidong, Xu Chunxiang, and Dai Ronghua

Subjects
Large flat-headed tower crane, Rotating mechanism, Driving device, Rotary support, Rotary resistance torque, Driving torque, Electronic control equipment runaway, Mechanical engineering and machinery, TJ1-1570
Abstract

With the two kinds of analysis methods of classification analysis and theoretical mechanical analysis,the runaway fault of the large flat-headed tower crane rotation is systematically analyzed,the possible reasons that could cause the tower crane rotation out of control are explained in detail,and the countermeasures of avoiding runaway fault and guaranteeing the tower crane safety are provided for its design,manufacture and its users.

Published
2018
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15. Dynamic distribution of gut microbiota during Alzheimer's disease progression in a mice model.

Author

Zhu, Jianshen, Liu, Shuyun, Zhang, Haoran, Zhao, Wenjing, Ding, Jinmei, Dai, Ronghua, Xu, Ke, He, Chuan, Liu, Jiajia, Yang, Lingyu, and Meng, He

Subjects
TRANSGENIC mice, GUT microbiome, ALZHEIMER'S disease, ANIMAL disease models, DISEASE progression, LABORATORY mice
Abstract

Alzheimer's disease (AD) is an irreversible neurodegenerative disease that affects more than 44 million people worldwide. The pathogenic mechanisms of AD still remain unclear. Currently, there are numerous studies investigating the microbiota–gut–brain axis in humans and rodents indicated that gut microbiota played a role in neurodegenerative diseases, including AD. However, the underlying relationship between the progress of AD disease and the dynamic distribution of gut microbiota is not well understood. In the present study, APPswe/PS1ΔE9 transgenic mice of different ages and sex were employed. After the evaluation of the AD mice model, gut metagenomic sequencing was conducted to reveal gut microbiota, moreover, probiotics intervention was treated in the AD mice. The results showed that (1) AD mice had reduced microbiota richness and a changed gut microbiota composition, and AD mice gut microbiota richness was correlated with cognitive performance. We have also found some potential AD‐related microbes, for example, in AD‐prone mice, the genus Mucispirillum was strongly associated with immune inflammation. (2) Probiotics intervention improved cognitive performance and changed gut microbiota richness and composition of AD mice. We revealed the dynamics distribution of gut microbiota and the effect of probiotics on AD in a mice model, which provides an important reference for the pathogenesis of AD, intestinal microbial markers associated with AD, and AD probiotic intervention. [ABSTRACT FROM AUTHOR]

Published
2023
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21. Intestinal Microbiota and Host Cooperate for Adaptation as a Hologenome

Author

Zhou, Hao, primary, Yang, Lingyu, additional, Ding, Jinmei, additional, Dai, Ronghua, additional, He, Chuan, additional, Xu, Ke, additional, Luo, Lingxiao, additional, Xiao, Lu, additional, Zheng, Yuming, additional, Han, Chengxiao, additional, Akinyemi, Fisayo T., additional, Honaker, Christa F., additional, Zhang, Yan, additional, Siegel, Paul B., additional, and Meng, He, additional

Published
2022
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33. Inheritance and Establishment of Gut Microbiota in Chickens

Author

Ding, Jinmei, primary, Dai, Ronghua, additional, Yang, Lingyu, additional, He, Chuan, additional, Xu, Ke, additional, Liu, Shuyun, additional, Zhao, Wenjing, additional, Xiao, Lu, additional, Luo, Lingxiao, additional, Zhang, Yan, additional, and Meng, He, additional

Published
2017
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35. Genetic pattern and gene localization of polydactyly in Beijing fatty chicken

Author

He, Chuan, primary, Chen, Yongcan, additional, Yang, Kaixuan, additional, Zhai, Zhengxiao, additional, Zhao, Wenjing, additional, Liu, Shuyun, additional, Ding, Jinmei, additional, Dai, Ronghua, additional, Yang, Lingyu, additional, Xu, Ke, additional, Zhou, Zhenxiang, additional, Gu, Caiju, additional, Huang, Qizhong, additional, and Meng, He, additional

Published
2017
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37. Gut Microbiota Co-microevolution with Selection for Host Humoral Immunity

Author

Yang, Lingyu, Liu, Shuyun, Ding, Jinmei, Dai, Ronghua, He, Chuan, Xu, Ke, Honaker, Christa F., Zhang, Yan, Siegel, Paul B., Meng, He, Yang, Lingyu, Liu, Shuyun, Ding, Jinmei, Dai, Ronghua, He, Chuan, Xu, Ke, Honaker, Christa F., Zhang, Yan, Siegel, Paul B., and Meng, He

Abstract

To explore coevolution between the gut microbiota and the humoral immune system of the host, we used chickens as the model organism. The host populations were two lines (HAS and LAS) developed from a common founder that had undergone 40 generations of divergent selection for antibody titers to sheep red blood cells (SRBC) and two relaxed sublines (HAR and LAR). Analysis revealed that microevolution of host humoral immunity contributed to the composition of gut microbiota at the taxa level. Relaxing selection enriched some microorganisms whose functions were opposite to host immunity. Particularly, Ruminococcaceae and Oscillospira enriched in high antibody relaxed (HAR) and contributed to reduction in antibody response, while Lactobacillus increased in low antibody relaxed (LAR) and elevated the antibody response. Microbial functional analysis showed that alterations were involved in pathways relating to the immune system and infectious diseases. Our findings demonstrated co-microevolution relationships of host-microbiota and that gut microorganisms influenced host immunity.

Published
2017
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38. Gut Microbiota Co-microevolution with Selection for Host Humoral Immunity

Author

Animal and Poultry Sciences, Yang, Lingyu, Liu, Shuyun, Ding, Jinmei, Dai, Ronghua, He, Chuan, Xu, Ke, Honaker, Christa F., Zhang, Yan, Siegel, Paul B., Meng, He, Animal and Poultry Sciences, Yang, Lingyu, Liu, Shuyun, Ding, Jinmei, Dai, Ronghua, He, Chuan, Xu, Ke, Honaker, Christa F., Zhang, Yan, Siegel, Paul B., and Meng, He

Abstract

To explore coevolution between the gut microbiota and the humoral immune system of the host, we used chickens as the model organism. The host populations were two lines (HAS and LAS) developed from a common founder that had undergone 40 generations of divergent selection for antibody titers to sheep red blood cells (SRBC) and two relaxed sublines (HAR and LAR). Analysis revealed that microevolution of host humoral immunity contributed to the composition of gut microbiota at the taxa level. Relaxing selection enriched some microorganisms whose functions were opposite to host immunity. Particularly, Ruminococcaceae and Oscillospira enriched in high antibody relaxed (HAR) and contributed to reduction in antibody response, while Lactobacillus increased in low antibody relaxed (LAR) and elevated the antibody response. Microbial functional analysis showed that alterations were involved in pathways relating to the immune system and infectious diseases. Our findings demonstrated co-microevolution relationships of host-microbiota and that gut microorganisms influenced host immunity.

Published
2017

41. Genome and metagenome analyses reveal adaptive evolution of the host and interaction with the gut microbiota in the goose

Author

Gao, Guangliang, primary, Zhao, Xianzhi, additional, Li, Qin, additional, He, Chuan, additional, Zhao, Wenjing, additional, Liu, Shuyun, additional, Ding, Jinmei, additional, Ye, Weixing, additional, Wang, Jun, additional, Chen, Ye, additional, Wang, Haiwei, additional, Li, Jing, additional, Luo, Yi, additional, Su, Jian, additional, Huang, Yong, additional, Liu, Zuohua, additional, Dai, Ronghua, additional, Shi, Yixiang, additional, Meng, He, additional, and Wang, Qigui, additional

Published
2016
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46. Metabolite profiling of l‐isocorypalmine in rat urine, plasma, and feces after oral administration using high performance liquid chromatography coupled to Fourier transform ion cyclotron resonance mass spectrometry.

Author

Li, Yiran, Zhang, Teng, Huai, Jiaxin, Cheng, Congcong, Xie, Linlin, Wang, Siqi, and Dai, Ronghua

Subjects
MASS spectrometry, HIGH performance liquid chromatography, PHARMACOKINETICS, ELECTROSPRAY ionization mass spectrometry, CYCLOTRONS
Abstract

l‐Isocorypalmine, an active alkaloid compound isolated from Rhizoma Corydalis yanhusuo, has been reported to possess biological activity for treating cocaine use disorder. A high‐performance liquid chromatography coupled to Fourier transform ion cyclotron resonance mass spectrometry method was established for identification of the metabolites of l‐isocorypalmine in urine, plasma and feces samples of rats after a single intragastric gavage of l‐isocorypalmine at a dose of 15 mg/kg. As a result, a total of 21 metabolites (six phase І metabolites and fifteen phase II metabolites) were detected and tentatively identified by mass spectrometry and fragment ions from tandem mass spectrometry spectra. All metabolites were present in the urine samples, nine metabolites were found in the plasma samples and three metabolites were found in the feces samples. Results indicated that metabolic pathways of l‐isocorypalmine included oxidation, dehydrogenation, demethylation, sulfate conjugation, and glucuronide conjugation. In addition, glucuronidation was the major metabolic reaction. Results of this investigation could provide significant experimental basis for efficacy, safety and action mechanism of l‐isocorypalmine, which will be advantageous to new drug development for treating cocaine addiction. [ABSTRACT FROM AUTHOR]

Published
2019
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