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15 results on '"Dai, De-Cai"'

8. Three new long-chain polyenes from the mangrove-derived fungus Penicillium herquei JX4

Author

Long, Kai-Yuan, Dai, De-Cai, Zheng, Cai-Juan, Wang, Yi-Tong, Song, Xin-Ming, Chen, Xuan, Zhou, Xue-Ming, and Chen, Guang-Ying

Subjects
Pharmacology, Complementary and alternative medicine, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, General Medicine, Analytical Chemistry
Abstract

One new epimer pair of long-chain polyenes penicilqueis E (1) and F (2), and one new long-chain polyene pinophol G (3), along with one known compound (4), were obtained from EtOAc extract of the mangrove-derived fungus Penicillium herquei JX4. Their structures were elucidated by detailed analysis of comprehensive spectroscopic data. The inhibitory activities of all compounds against the nitric oxide (NO) production induced by lipopolysaccharide in mouse macrophage RAW 264.7 cells in vitro were evaluated.

Published
2022

9. Two new anthraquinone derivatives from Saprosma crassipes H. S. Lo.

Author

Ji, Xin-Shu, Dai, De-Cai, Wang, Yi-Tong, Cui, Jing-Yi, Li, Hai-Xiang, Song, Xin-Ming, Yi, Ji-Ling, and Zhou, Xue-Ming

Subjects
ANTHRAQUINONE derivatives, MICROCOCCUS luteus, BACILLUS cereus, ANTIBACTERIAL agents, ESCHERICHIA coli
Abstract

Two new anthraquinone derivatives sapranquinones A and B (1 and 2) together with two known biogenetically related anthraquinone derivatives (3 and 4) were isolated from the stems of Saprosma crassipes H. S. Lo. The structures of these compounds were elucidated using comprehensive spectroscopic methods. Compounds 1-4 were evaluated for their antibacterial activities and compounds 1 and 3 had a broad spectrum antibacterial activity against Staphylococcus albus, Escherichia coli, Bacillus cereus, Micrococcus tetragenus, and Micrococcus luteus with MIC values ranging from 1.25 to 5 μg/mL. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Three new long-chain polyenes from the mangrove-derived fungus Penicillium herquei JX4.

Author

Long, Kai-Yuan, Dai, De-Cai, Zheng, Cai-Juan, Wang, Yi-Tong, Song, Xin-Ming, Chen, Xuan, Zhou, Xue-Ming, and Chen, Guang-Ying

Subjects
*SOILS, *LIPOPOLYSACCHARIDES, *ANIMAL experimentation, *ANTI-inflammatory agents, *POLYENES, *FUNGI, *MACROPHAGES, *HEALTH outcome assessment, *RESEARCH funding, *PLANT extracts, *MOLECULAR structure, *NITRIC oxide, *BIOLOGICAL assay, *MICE, *SPECTRUM analysis, *FERMENTATION
Abstract

One new epimer pair of long-chain polyenes penicilqueis E (1) and F (2), and one new long-chain polyene pinophol G (3), along with one known compound (4), were obtained from EtOAc extract of the mangrove-derived fungus Penicillium herquei JX4. Their structures were elucidated by detailed analysis of comprehensive spectroscopic data. The inhibitory activities of all compounds against the nitric oxide (NO) production induced by lipopolysaccharide in mouse macrophage RAW 264.7 cells in vitro were evaluated. [ABSTRACT FROM AUTHOR]

Published
2023
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14. Two new anthraquinone derivatives from Saprosma crassipes H. S. Lo

Author

Ji, Xin-Shu, Dai, De-Cai, Wang, Yi-Tong, Cui, Jing-Yi, Li, Hai-Xiang, Song, Xin-Ming, Yi, Ji-Ling, and Zhou, Xue-Ming

Subjects
Organic Chemistry, Plant Science, Biochemistry, Analytical Chemistry
Abstract

Two new anthraquinone derivatives sapranquinones A and B (1 and 2) together with two known biogenetically related anthraquinone derivatives (3 and 4) were isolated from the stems of Saprosma crassipes H. S. Lo. The structures of these compounds were elucidated using comprehensive spectroscopic methods. Compounds 1-4 were evaluated for their antibacterial activities and compounds 1 and 3 had a broad spectrum antibacterial activity against Staphylococcus albus, Escherichia coli, Bacillus cereus, Micrococcus tetragenus, and Micrococcus luteus with MIC values ranging from 1.25 to 5 μg/mL.

Published
2022
Full Text
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