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In this investigation, the multi-objective selection and optimization of a gantry machine tool is achieved by analytic hierarchy process, multi-objective genetic algorithm, and Pareto-Edgeworth-Grierson–multi-criteria decision-making method. The objectives include maximum static deformation, the first four natural frequencies, mass, and fabrication cost of the gantry. Further structural optimization of the best configuration was accomplished using multi-objective genetic algorithm to improve all objectives except cost. The result of sensitivity analysis reveals the major contribution of columns of gantry with respect to the crossbeam’s contribution. After determining the most effective geometrical parameters using sensitivity analysis, multi-objective genetic algorithm was performed to obtain the Pareto-optimal solutions. In order to choose the final configuration, Pareto-Edgeworth-Grierson–multi-criteria decision-making was applied. The procedure outlined in this article could be used for selection and optimization of gantry as quantitative method as opposed to traditional qualitative method exploited in industrial application for design of gantry. [ABSTRACT FROM AUTHOR]

Purpose: Sentinel lymph node biopsy is a fairly new approach for staging of gynecological malignancies. In the current study, the authors comprehensively reviewed the available reports on sentinel node biopsy of endometrial cancer., Materials and Methods: The authors searched Medline, SCOPUS, ISI web of knowledge, Science Direct, Springer, OVID SP, and Google Scholar with the following search terms: "endometrium OR endometrial OR uterine OR uterus AND sentinel". The outcomes of interest were detection rate and sensitivity., Results: Overall, 35 studies had enough information for false negative rate evaluation and 51 studies (including the sub-groups of individual studies) for detection rate evaluation (2,071 patients overall). Pooled detection rate was 77.8% (95% CI: 73.5-81.5%) and pooled sensitivity was 89% (95% CI: 83-93%). Cervical injection, as well as using both blue dye and radiotracer, results in higher detection rate and sensitivity. New techniques such as fluorescent dye injection and robotic-assisted surgery showed high detection rate and sensitivity., Conclusion: Sentinel node mapping is feasible in endometrial cancer. Using both blue dye and radiotracer and cervical injection of the mapping material can optimize the sensitivity and detection rate of this technique. Larger studies are still needed to evaluate the false negative rate and the factors influencing the sensitivity before considering this method safe.

Cancer of the testis is uncommon in young males. It can present in unusual ways. We are presenting a case of testicular cancer presenting as an epididymal lesion that was diagnosed after epididymectomy.