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4. Further delineation and long-term evolution of electroclinical phenotype in Mowat Wilson Syndrome. A longitudinal study in 40 individuals

Author

Ricci, Emilia, Fetta, Anna, Garavelli, Livia, Caraffi, Stefano, Ivanovski, Ivan, Bonanni, Paolo, Accorsi, Patrizia, Giordano, Lucio, Pantaleoni, Chiara, Romeo, Antonino, Arena, Alessia, Bonetti, Silvia, Boni, Antonella, Chiarello, Daniela, Di Pisa, Veronica, Epifanio, Roberta, Faravelli, Francesca, Finardi, Erica, Fiumara, Agata, Grioni, Daniele, Mammi, Isabella, Negrin, Susanna, Osanni, Elisa, Raviglione, Federico, Rivieri, Francesca, Rizzi, Romana, Savasta, Salvatore, Tarani, Luigi, Zanotta, Nicoletta, Dormi, Ada, Vignoli, Aglaia, Canevini, Mariapaola, and Cordelli, Duccio M.

Published
2021
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6. Non-coronary cardiac events, younger age, and IVIG unresponsiveness increase the risk for coronary aneurysms in Italian children with Kawasaki disease

Author

Fabi, Marianna, Andreozzi, Laura, Frabboni, Ilaria, Dormi, Ada, Corinaldesi, Elena, Lami, Francesca, Cicero, Cristina, Tchana, Bertrand, Francavilla, Rosa, Sprocati, Monica, Bigucci, Barbara, Balsamo, Claudia, Valin, Paola Sogno, Di Fazzio, Giorgia, Iughetti, Lorenzo, Valletta, Enrico, Marchetti, Federico, Donti, Andrea, and Lanari, Marcello

Published
2021
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8. Prospective Study of Sars-cov2 Associated Coagulopathy and Role of Complement Activation

Author

Silingardi, Mauro, primary, Zappulo, Fulvia, additional, Dormi, Ada, additional, Pizzini, Attilia Maria, additional, Donadei, Chiara, additional, Fantoni, Chiara, additional, Zaccaroni, Stefania, additional, Pizzuti, Valeria, additional, Cilloni, Nicola, additional, Tantillo, Simona, additional, Guidi, Antonella, additional, Mancini, Rita, additional, Manna, Gaetano La, additional, and Comai, Giorgia, additional

Published
2024
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12. Classification Systems of Endometrial Cancer: A Comparative Study about Old and New

Author

Coada, Camelia Alexandra, primary, Dondi, Giulia, additional, Ravegnini, Gloria, additional, De Leo, Antonio, additional, Santini, Donatella, additional, De Crescenzo, Eugenia, additional, Tesei, Marco, additional, Bovicelli, Alessandro, additional, Giunchi, Susanna, additional, Dormi, Ada, additional, Di Stanislao, Marco, additional, Morganti, Alessio G., additional, De Biase, Dario, additional, De Iaco, Pierandrea, additional, and Perrone, Anna Myriam, additional

Published
2021
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13. Defining renal remission in an international cohort of 248 children and adolescents with lupus nephritis

Author

De Mutiis, Chiara, primary, Wenderfer, Scott E, additional, Orjuela, Alvaro, additional, Bagga, Arvind, additional, Basu, Biswanath, additional, Sar, Tanmoy, additional, Aggarwal, Amita, additional, Jain, Avinash, additional, Yap, Hui-Kim, additional, Ito, Shuichi, additional, Ohnishi, Ai, additional, Iwata, Naomi, additional, Kasapcopur, Ozgur, additional, Laurent, Audrey, additional, Mastrangelo, Antonio, additional, Ogura, Masao, additional, Shima, Yuko, additional, Rianthavorn, Pornpimol, additional, Silva, Clovis A, additional, Trindade, Vitor, additional, Dormi, Ada, additional, and Tullus, Kjell, additional

Published
2021
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14. Understanding the environmental factors related to the decrease in Pediatric Emergency Department referrals for acute asthma during the SARS‐CoV‐2 pandemic

Author

Dondi, Arianna, primary, Betti, Ludovica, additional, Carbone, Claudio, additional, Dormi, Ada, additional, Paglione, Marco, additional, Rinaldi, Matteo, additional, Gualtieri, Maurizio, additional, Scotto, Fabiana, additional, Poluzzi, Vanes, additional, Fabi, Marianna, additional, and Lanari, Marcello, additional

Published
2021
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15. Pigmented purpuric dermatoses: analysis of epidemiological, clinical and histopathological aspects in relation to the prognosis of 70 patients, including infants and adults

Author

SACCHELLI, Lidia, primary, DI ALTOBRANDO, Ambra, additional, MISCIALI, Cosimo, additional, BARALDI, Carlotta, additional, SECHI, Andrea, additional, GUARALDI, Fabio, additional, VAROTTI, Elisa, additional, DORMI, Ada, additional, NARDI, Elena, additional, and PATRIZI, Annalisa, additional

Published
2021
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18. Evaluation of twelve formulas for LDL-C estimation in a large, blinded, random Italian population.

Author

Piani, Federica, primary, Cicero, Arrigo F.G., additional, Ventura, Fulvio, additional, Dormi, Ada, additional, Fogacci, Federica, additional, Patrono, Daniela, additional, Mancini, Rita, additional, Ramazzotti, Eric, additional, Borghi, Claudio, additional, D'Addato, Sergio, additional, Bove, Marilisa, additional, Giovannini, Marina, additional, Grandi, Elisa, additional, Rizzoli, Elisabetta, additional, and Rossolini, Arianna, additional

Published
2021
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28. Non-coronary cardiac events, younger age, and IVIG unresponsiveness increase the risk for coronary aneurysms in Italian children with Kawasaki disease

Author

Fabi, Marianna, primary, Andreozzi, Laura, additional, Frabboni, Ilaria, additional, Dormi, Ada, additional, Corinaldesi, Elena, additional, Lami, Francesca, additional, Cicero, Cristina, additional, Tchana, Bertrand, additional, Francavilla, Rosa, additional, Sprocati, Monica, additional, Bigucci, Barbara, additional, Balsamo, Claudia, additional, Valin, Paola Sogno, additional, Di Fazzio, Giorgia, additional, Iughetti, Lorenzo, additional, Valletta, Enrico, additional, Marchetti, Federico, additional, Donti, Andrea, additional, and Lanari, Marcello, additional

Published
2020
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36. Advances in Legionella Control by a New Formulation of Hydrogen Peroxide and Silver Salts in a Hospital Hot Water Network

Author

Girolamini, Luna, primary, Dormi, Ada, additional, Pellati, Tiziana, additional, Somaroli, Paolo, additional, Montanari, Davide, additional, Costa, Andrea, additional, Savelli, Francesca, additional, Martelli, Andrea, additional, Grottola, Antonella, additional, Fregni Serpini, Giulia, additional, and Cristino, Sandra, additional

Published
2019
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39. Tinnitus in elderly patients and prognosis of mild-to-moderate congestive heart failure: a cross-sectional study with a long-term extension of the clinical follow-up

Author

Cicero Arrigo FG, Veronesi Maddalena, Rimondi Maria C, Brandolini Cristina, Rinaldi Elisa R, Cosentino Eugenio R, Borghi Claudio, Dormi Ada, and Pirodda Antonio

Subjects
Medicine
Abstract

Abstract Background The complex mechanism responsible for tinnitus, a symptom highly prevalent in elderly patients, could involve an impaired control of the microcirculation of the inner ear, particularly in patients with poor blood pressure control and impaired left ventricular (LV) function. Methods In order to define the relationship between the presence of tinnitus and the severity and clinical prognosis of mild-to-moderate chronic heart failure (CHF) in a large population of elderly patients (N = 958), a cross-sectional study was conducted with a long-term extension of the clinical follow-up. Blood pressure, echocardiographic parameters, brain natriuretic peptide (BNP), hospitalization, and mortality for CHF were measured. Multivariate logistic regression analysis was used to assess the association between the presence of tinnitus and some of the prognostic determinants of heart failure. Results The presence of tinnitus was ascertained in 233 patients (24.3%; mean age 74.9 ± 6 years) and was associated with reduced systolic and diastolic blood pressure (123.1 ± 16/67.8 ± 9 vs 125.9 ± 15/69.7 ± 9; P = .027/P = .006), reduced LV ejection fraction (LVEF%; 43.6 ± 15 vs 47.9 ± 14%, P = .001), and increased BNP plasma levels (413.1 ± 480 vs 286.2 ± 357, P = .013) in comparison to patients without symptoms. The distribution of CHF functional class was shifted toward a greater severity of the disease in patients with tinnitus. Combined one-year mortality and hospitalization for CHF (events/year) was 1.43 ± 0.2 in patients with tinnitus and 0.83 ± 0.1 in patients without tinnitus, with an adjusted hazard ratio (HR) of 0.61 (95% confidence interval (CI): 0.37 to 0.93, P Conclusions Our preliminary data indirectly support the hypothesis that tinnitus is associated with a worse CHF control in elderly patients and can have some important clinical implications for the early identification of patients who deserve a more aggressive management of CHF.

Published
2011
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40. Association of serum C3 levels with the risk of myocardial infarction

Author

Muscari, Antonio, Bozzoli, Claudio, Puddu, Giovanni M., Sangiorgi, Zina, Dormi, Ada, Rovinetti, Carlotta, Descovich, Gian C., and Puddu, Paolo

Subjects
Complement (Immunology) -- Analysis, Immunoglobulins -- Physiological aspects, Heart attack -- Risk factors, Health, Health care industry
Abstract

PURPOSE: Serum complement and IgA levels have been found to be retrospectively associated with the presence of diffuse atherosclerosis. This study was performed to assess whether serum immunoglobulins and complement components are predictive of future ischemic events. PATIENTS AND METHODS: The baseline values of IgG, IgA, IgM, C3, and C4 were measured in the sera from a cohort of 860 inhabitants of the town of Brisighella, Italy. They were 444 men and 416 women, mean age 53.9 years (SD 12.4, range 23 to 84), who had not had any ischemic events (myocardial infarction [MI], angina pectoris, stroke, transient ischemic attack, or intermittent claudication) at the time of blood sampling in 1984. Their baseline values for the main recognized risk factors for atherosclerosis were known at baseline and for 4 years of follow-up. Multiple logistic regression analysis was performed for associations between ischemic events and immunologic variables (including serum IgG, IgA, IgM, C3, and C4) and risk factors for atherosclerosis (including age, sex, diastolic blood pressure, cigarette consumption, Quetelet index, total cholesterol, HDL cholesterol, triglycerides and blood glucose). RESULTS: During follow-up, 57 subjects experienced ischemic events, including 28 cases of coronary heart disease (17 MI and 11 angina pectoris). Of the immunologic variables studied, only serum C3 was found to be independently associated with ischemic events (P

Published
1995

43. Gastrointestinal presentation of Kawasaki disease: A red flag for severe disease?

Author

Fabi, Marianna, primary, Corinaldesi, Elena, additional, Pierantoni, Luca, additional, Mazzoni, Elisa, additional, Landini, Chiara, additional, Bigucci, Barbara, additional, Ancora, Gina, additional, Malaigia, Laura, additional, Bodnar, Tetyana, additional, Di Fazzio, Giorgia, additional, Lami, Francesca, additional, Valletta, Enrico, additional, Cicero, Cristina, additional, Biasucci, Giacomo, additional, Iughetti, Lorenzo, additional, Marchetti, Federico, additional, Sogno Valin, Paola, additional, Amarri, Sergio, additional, Brusa, Sandra, additional, Sprocati, Monica, additional, Maggiore, Giuseppe, additional, Dormi, Ada, additional, Lanzoni, Paolo, additional, Donti, Andrea, additional, and Lanari, Marcello, additional

Published
2018
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44. Long-term Effect of a Dietary Education Program on Postmenopausal Cardiovascular Risk and Metabolic Syndrome: The Brisighella Heart Study

Author

CICERO, ARRIGO FRANCESCO GIUSEPPE, DORMI, ADA, D'ADDATO, SERGIO, GADDI, ANTONIO VITTORINO, BORGHI, CLAUDIO, Brisighella Heart Study Group, Cicero AFG, Dormi A, D’Addato S, Gaddi AV, Borghi C, and Brisighella Heart Study Group.

Subjects
Blood Glucose, cardiovascular risk, medicine.medical_specialty, Population, General Population Cohort, metabolic syndrome, Body Mass Index, chemistry.chemical_compound, High-density lipoprotein, Internal medicine, medicine, Health Status Indicators, Humans, Longitudinal Studies, education, Triglycerides, Aged, education.field_of_study, postmenopausal, business.industry, Brisighella Heart Study, General Medicine, Blood Pressure Monitoring, Ambulatory, Middle Aged, medicine.disease, Lipids, Diet, Perimenopause, Postmenopause, Menopause, dietary education, Blood pressure, chemistry, Cardiovascular Diseases, Low-density lipoprotein, Physical therapy, Female, Metabolic syndrome, business, Body mass index, Program Evaluation
Abstract

OBJECTIVE: To evaluate whether a nutritional education intervention on a general population cohort is able to balance the metabolic effects of incident menopause in a large sample of perimenopausal women. METHODS: We measured body mass index (BMI), blood pressure, plasma lipids, fasting plasma glucose, and prevalence of metabolic syndrome in two groups of perimenopausal nondiabetic women involved in the Brisighella Heart Study, a longitudinal epidemiological study, before (sample size 301) and after (sample size 262) a nutritional education program aimed at improving the cardiovascular disease (CVD) risk profile in a whole village population. RESULTS: Before the interventional period, women undergoing menopause experienced a significant increase in BMI, systolic blood pressure, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (LDL-C), and triglycerides (all parameters exhibited p < 0.01). After the nutritional intervention, women undergoing menopause experienced a significant reduction only in triglyceride plasma level (p < 0.001). Metabolic syndrome prevalence was 73 in 301 and 99 in 301 (p = 0.018), respectively, before and after menopause in the preintervention group, and it was 66 in 262 and 68 in 262 (p = 0.871), respectively, in the postintervention group. CONCLUSIONS: In our study, a nutritional education program aimed at improving the CVD risk profile of a whole village population is associated with the prevention of increase in systolic blood pressure, BMI, cholesterolemia, and metabolic syndrome prevalence linked to menopause.

Published
2010
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46. Nella babele del rischio: Rischio Globale e Rischio Relativo

Author

DORMI, ADA and Dormi Ada

Abstract

la modalità più appropriata per identificare le persone a rischio di ammalare è la valutazione del rischio globale assoluto, calcolato considerando insieme i valori di più fattori di rischio. Il rischio globale esprime la probabilità di ammalarsi (di infarto o ictus) nel corso dei successivi 10 I risultati del Brisighella Heart study hanno confermato l'importanza di stimare il rischio globale in popolazione per pianificare un progetto di prevenzione primaria

Published
2009

49. Trends in blood pressure control and antihypertensive treatment in clinical practice: the Brisighella Heart Study

Author

BORGHI, CLAUDIO, DORMI, ADA, D'ADDATO, SERGIO, GADDI, ANTONIO VITTORINO, AMBROSIONI, ETTORE, on behalf of the Brisighella Heart Study Working Party, Borghi, Claudio, Dormi, Ada, D'Addato, S, Gaddi, Antonio, Ambrosioni, Ettore, and on behalf of the Brisighella Heart Study Working Party

Subjects
Male, medicine.medical_specialty, Combination therapy, Physiology, Population, Diastole, Blood Pressure, law.invention, Cohort Studies, Pharmacotherapy, Randomized controlled trial, law, Risk Factors, Internal medicine, Internal Medicine, medicine, Humans, Sex Distribution, education, Antihypertensive Agents, Aged, education.field_of_study, business.industry, Risk Factor, Middle Aged, Antihypertensive Agent, Endocrinology, Blood pressure, Cohort, Hypertension, Drug Therapy, Combination, Female, Cohort Studie, Cardiology and Cardiovascular Medicine, business, Cohort study, Human
Abstract

OBJECTIVES: To assess trends in blood pressure (BP) awareness, control, treatment and use of different antihypertensive medications in a cohort of hypertensive patients. DESIGN: This study summarizes the results of a 12-year observation (1984-1996) of a cohort of 940 hypertensive patients from the population of 2329 participants to the Brisighella Heart Study (BHS). Primary outcome measures were the extent of BP control (systolic/diastolic BP < 140/90 mmHg) and prevalence of the use of various antihypertensive medications. RESULTS: From 1984 to 1996 the proportion of patients aware of elevated BP and treated for hypertension rose from 73 to 88% and from 43.8 to 50.3% in men, and from 77 to 87% and from 50 to 56.6% in women (P < 0.001 for all). The rate of BP control increased from 7.5 to 17.4% in men (P < 0.001) and from 7.3 to 18.5% in women (P < 0.001). This occurred with increased use of combination therapy (+0.2 drugs/person) and with a decline in the use of diuretics (-38.2% men and -28% women; P < 0.001) and an increase in use of calcium-channel blockers (CCBs) (24.2% in men and 12.2% in women; P < 0.001) and angiotensin-converting enzyme (ACE) inhibitors (30.7% in men and 30.8% in women; P < 0.001) as first-line drugs. The improved BP control was associated with a lower rate of fatal and non-fatal cardiovascular (CV) events. CONCLUSIONS: The results of this observational study confirm that the rate of BP control can be improved in daily clinical practice by increasing the use of drug combinations, as well as by the first-line prescription of ACE inhibitors and CCBs [and probably angiotensin II receptor inhibitors (ARBs)].

Published
2004

50. Lo studio Brisighella: 40 anni di ricerca nella prevenzione delle malattie cardiovascolari

Author

D'ADDATO, SERGIO, DORMI, ADA, CICERO, ARRIGO FRANCESCO GIUSEPPE, GRANDI, ELISA, RIZZOLI, ELISABETTA, BORGHI, CLAUDIO, Borlotti M. L., Rosticci M., Giovannini M., D'Addato S., Dormi A., Cicero A.F.G., Borlotti M.L., Grandi E., Rosticci M., Rizzoli E., Giovannini M., and Borghi C

Subjects
prevenzione, ipertensione arteriosa, epidemiologia, malattie cardiovascolari
Abstract

Lo studio di Brisghella iniziato nel 1972 per volontà del Professor Giancarlo Descovich è articolato in varie fasi. Una prima osservazionale longitudinale, con lo scopo di monitorare, con controlli quadriennali, l'andamento dei principali fattori di rsichio per le malattie cardiovascolari. Nel 1984 iniziò una fase di intervento che prevedeva una azione multipla: sulla popolazione generale, sulla popolazione scolastica (elementari e medie), sui soggetti definiti ad alto rischio cardiovascolare. La stragtegia di intervento ha portato ad una riduzione dei livelli lipidici, del numero di fattori di rischio che si associano nei singoli cittadini e del numero degli eventi cardiovascolari nella popolazione. Dopo il 1990 si è proseguito con una nuova fase longitudinale con controlli quadriennali. I dati di Brisighella dimostrano una correlazione forte tra i livelli lipidici e pressione arteriosa, definendo la colesterolemia un fattore correlato all'innalzamento dei livelli pressori in accordo con altri studi internazionali. Sono stati studiati i fattori associati allo sviluppo di diabete di tipo 2 e la stima della prelevalenza della Iperlipoprotenemia Familiare Combinata. E' stata valuta la correlazione fra ormoni sessuali, adipochine e patter metabolico e la correlazione tra attività fisica ed eventi cardiovascolari. Brisighella ha fornito dati come popolazione di controllo all'interno dell'ambizioso progetto DIAL-ER (Diagnostica avanza in lipidologia-Emilia-Romagna). Qust'anno è iniziato il survey di popolazione arruolata all'inizio (40 anni fa), che prevede anche l'arruolamento degli offsprings ed include la valutazione di parametri strumentali su tutta la popolazione (pulse-Wave Anlysis, Pulse Wave Velocity, Augmentation Index, ABI) ed un set di marcatori laboratoristici di rischio cardiometabolico quali microalbuminuria, marcatori di insulino-resistenza, flogosi sistemica e di metabolismo del tessuto adiposo.

Published
2013

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