Search

El examen de rutina de los donantes de órganos para detectar la infección por el virus de la inmunodeficiencia humana (HIV) ha hecho que la transmisión del virus mediante el trasplante de órganos sea poco común. Sin embargo, a pesar de las pruebas de detección de rutina, la transmisión del HIV continúa siendo un riesgo del trasplante de órganos ya que, a diferencia de los tejidos, los órganos sólidos no se pueden procesar, desinfectar, ni modificar para inactivar patógenos infecciosos. A continuación, se describe un caso de posible transmisión de HIV por trasplante de órganos de un donante previamente seronegativo a dos de sus receptores.

Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introducción: El síndrome metabólico (SM) está asociado a un incremento del riesgo cardiovascular. Los donantes de sangre son una población aparentemente sana en donde ciertas características cardiometabolicas no son evaluadas en su selección, existiendo limitada información sobre su presencia. Objetivo: Determinar la frecuencia de síndrome metabólico y sus características metabólicas en donantes de sangre. Materiales y métodos: Estudio transversal realizado en 244 donantes de sangre entre 18 y 55 años que acudieron al Servicio de Hemoterapia y Banco de sangre del Hospital Cayetano Heredia en Lima- Perú, durante el mes de mayo del 2023. Se realizó el diagnóstico de SM según los criterios del Adult Treatment Panel III (ATP III). Se realizó un análisis bivariado entre el SM y características metabólicas con el sexo y se consideró un nivel de significancia del 5%. Resultados: El 63.9% de los donantes de sangre fueron del sexo masculino. El 43.6 % de la población presentó SM. Las características más frecuentes fueron la hipertrigliceridemia (54.5%), obesidad abdominal (51.2%) y lipoproteina de alta densidad (HDL) bajo (48.8%). El rango de edad de 40 a 49 años presentó la mayor frecuencia de SM (14.3%). La hipertrigliceridemia y presión arterial elevada estuvieron asociadas al sexo masculino (p=0.003 y p=0.019 respectivamente), mientras que el HDL bajo al sexo femenino (p

Introduction: SARS-CoV-2 has had a negative and significant impact on global health systems, threatening the necessary blood supply for clinical transfusions. Objective: To describe the causes of rejection of blood donors during the COVID-19 pandemic. Methods: An observational, cross-sectional and retrospective study was carried out in a population of donors who attended the Blood Bank of Ramiro Prialé Prialé National Hospital, in Huancayo, Peru, from July, 2020 to the same month, 2022. The analyzed variables were sex, the ABO blood group, Rh factor and types and causes of rejection. Results: Of total of 10 177 blood donors, 3390 (33.3%) were differed and excluded; the most frequent cause of differing was the low hematocrit (18.0%) and the most frequent cause of exclusion was antibody to hepatitis B core antigen positivity (36.8%). Likewise, male sex predominated among those who were rejected (55.2%) and an increment of the polytomous tendency was evidenced in differed (R²=0.2214) and excluded donors (R²=0.1178). Conclusions: The prevalence of differing and exclusion in blood donors was relatively high compared to that reported in other studies, which was mainly due, in each respective case, to the low hematocrit and the presence of antibody to hepatitis B core antigen. [ABSTRACT FROM AUTHOR]

Introduction: SARS-CoV-2 has had a negative and significant impact on global health systems, threatening the necessary blood supply for clinical transfusions. Objective: To describe the causes of rejection of blood donors during the COVID-19 pandemic. Methods: An observational, cross-sectional and retrospective study was carried out in a population of donors who attended the Blood Bank of Ramiro Prialé Prialé National Hospital, in Huancayo, Peru, from July, 2020 to the same month, 2022. The analyzed variables were sex, the ABO blood group, Rh factor and types and causes of rejection. Results: Of total of 10 177 blood donors, 3390 (33.3%) were differed and excluded; the most frequent cause of differing was the low hematocrit (18.0%) and the most frequent cause of exclusion was antibody to hepatitis B core antigen positivity (36.8%). Likewise, male sex predominated among those who were rejected (55.2%) and an increment of the polytomous tendency was evidenced in differed (R²=0.2214) and excluded donors (R²=0.1178). Conclusions: The prevalence of differing and exclusion in blood donors was relatively high compared to that reported in other studies, which was mainly due, in each respective case, to the low hematocrit and the presence of antibody to hepatitis B core antigen.

Objetivo: determinar la relación entre el Ret-He con diferentes categorías según la concentración de hemoglobina en candidatos a donar sangre. Materiales y Métodos: Se realizó un estudio transversal a partir de la revisión de 227 historias clínicas de candidatos a donar sangre durante el mes de diciembre del 2021 en el Servicio de Banco de Sangre y Hemoterapia del Hospital Cayetano Heredia. Se categorizó en 3 grupos según los niveles de hemoglobina: Grupo 1: ≥12,5 g/dl (mujeres) - ≥13,5 g/dl (varones). Grupo 2: 12 g/dl ≥ mujeres

In Cuba there is wide experience in intersectoral work to solve health problems in the community and the management of blood donations is no exception. The objective of this work was to document the intersectoral work in the management of blood donations in Cuba and to provide theoretical elements that contribute to its improvement. A bibliographic review of the literature on intersectoriality and the processes for the management of blood donations in the country was carried out; For this, works published on Internet sites were consulted, as well as texts and other documents available in repositories of the Infomed web portal network. Intersectoriality is theorized and illustrated as a managerial technology and its use and importance applied in the promotion, capture and recruitment of potential donors and in the organization of blood collections. It is concluded that the use of intersectoriality in the health management of voluntary blood donations, strengthens and distinguishes the Cuban Blood Donation Program in relation to the rest of the world, however, it is necessary to improve the strategic alliances between the health sector and other sectors of organized civil society involved in the activities that comprise this process.

Introducción: las hepatitis virales son un problema en la salud pública mundial y son una de las enfermedades que afectan al hombre. Objetivo: conocer la seroprevalencia del antígeno de superficie de la hepatitis B en donantes de sangre. Métodos: se realizó un estudio retrospectivo con el objetivo de determinar la seroprevalencia del virus de la hepatitis B en 93 440 donantes en el Banco de sangre provincial “Renato Guitart Rosell” de Santiago de Cuba. El período estudiado estuvo comprendido de octubre de 2015 a mayo de 2016. Resultados: se mostró un ligero decrecimiento de la prevalencia de portadores de antígeno de superficie de la hepatitis B a través de los tres años estudiados. La mayor reactividad a este marcador estuvo en el grupo de 41 a 50 años y predominó el sexo masculino. Se encontró que el 0,30% resultó seropositivo al virus de la hepatitis B. Conclusiones: el cumplimiento de los procedimientos establecidos para la adecuada selección del donante de sangre y la calidad y la seguridad de los resultados en las determinaciones de laboratorio de la prevalencia de portadores de antígeno de superficie de la hepatitis B, unido al reclutamiento de donantes de sangre voluntarios, altruistas no remunerados, ha permitido que se logre una baja seroprevalencia en la Provincia de Santiago de Cuba.

Copyright of CES Medicina is the property of Universidad CES and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: several units of blood, from voluntary donors, are discarded due to changes in organoleptic characteristics often caused by the presence of lipemia. Objective: to identify predictors of lipemia in hiperimmune plasma donors, in the provincial Blood Bank of Camagüey, from 2018 to 2021. Methods: a retrospective, case-control, analytic and observational study was performed on donors and the time period defined in the objective. The sample comprised 226 donors, divided into two groups at a 1:1 ratio, one group of cases with those diagnosed with lipemia and another control group without lipemia. Descriptive and inferential statistics were used for data processing. Results: there was a predominance of plasma donors between 40 and 49 years of age (42 %), males (85 %) and more than five years in the program (42.9 %). The variables: sex, nutritional status, physical inactivity, smoking, triglycerides level, cholesterol level, time in the plasmapheresis program and intensity of donations, showed significant statistical association with the appearance of lipemia. The variables with greater predictive capacity were: nutritional status, smoking, triglycerides level, total cholesterol level and time in the plasmapheresis program . Conclusions: being overweight or obese, smoking, altered triglycerides and total cholesterol levels, and being more than five years in the plasmapheresis program, are predictors of a probable diagnosis of lipemia in plasma donors.

Medicine has had a vertiginous advance in the last two centuries. After the first successful transfusions, transfusional medicine and blood banks arose. The ladder perform vital functions, from donor screening to the studies for the analysis of blood that are carried out before its use for transfusion and the follow-up of patients who receive blood components. Molecular biology is highly relevant in these activities, since it has allowed the reduction of window periods for the detection of diseases transmissible by blood; it has allowed the complete study of the typing of blood groups and HLA molecules, and it has allowed the adequate phenotypic interpretation of patients and donors by being able to have their genotype. The most relevant impact of the implementation of molecular biology techniques was the screening for the detection of transfusion-transmissible diseases in blood donors, which has allowed improving the safety of the components obtained. Molecular biology techniques applied in the study of the donor-recipient have allowed better care of patients who have required a transfusion or transplant. In this work, it is reviewed the importance of molecular biology in blood banks, with which the care for the Instituto Mexicano del Seguro Social beneficiaries has improved, as well as for the blood donors who are mostly not insured. [ABSTRACT FROM AUTHOR]

Background: The mobile campaigns of altruistic blood donation are one of the main actions of the Blood Bank of the Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez". With the arrival of the new normal, after the COVID-19 pandemic, it was necessary to reactivate these actions according to the population's characteristics. Objective: To identify socio-cultural characteristics that enhance or limit voluntary or altruistic blood donation. Material and methods: Qualitative exploratory research, through a semi-structured interview with stratified sampling, universe of partial population of those attending blood donation; only altruistic donors were considered randomly, and representative proportions of the population subgroup were determined. Results: Most of the donors interviewed were preliminary donors who approached the blood donationt tent without focused promotion. Health professionals showed greater identification to altruistic blood donation. Donors declared a lack of donation culture as the main factor limiting this human activity. Finally, they considered the accessibility to the blood donationt tent as determinant for altruistic blood donation. Conclusions: 12 recommendations were established to the Blood Bank, with which the intention is to propose strategies and establish research channels that increase the impact on the promotion of altruistic blood donation in future campaigns. [ABSTRACT FROM AUTHOR]

Copyright of Texto & Contexto Enfermagem is the property of Universidade Federal de Santa Catarina, Programa de Pos-Graduacao de Enfermagem and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of ESPOCH Congresses: The Ecuadorian Journal of S.T.E.A.M. is the property of Knowledge E DMCC and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

El objetivo del estudio fue determinar el nivel de conocimientos sobre donación de sangre que tienen los pacientes externos que acuden a un hospital en Bagua Grande. Se realizó un estudio descriptivo transversal durante mayo a julio del 2019. Se elaboró y aplicó un cuestionario estructurado. Se captó a 244 personas que acudieron a consultorios externos mediante un muestreo sistemático. Los participantes obtuvieron una media de respuestas correctas de 8,90 (DE: 3,25) puntos de un total de 21. Se encontró que la edad y el grado de instrucción estaban correlacionados con el puntaje (rho = -0,21; p < 0,001 y rho = 0,38; p < 0,001, respectivamente). La procedencia y ocupación afectaron al puntaje (p < 0,001). Los conocimientos hallados en la población estudiada son bajos, pero esto no estaría relacionado con el antecedente de donación. Las intervenciones que se elaboren para mejorar la donación de sangre no solo se deben enfocar en brindar conocimientos, ya que otros factores estarían más relacionados con este resultado.

In Cuba there is wide experience in intersectoral work to solve health problems in the community and the management of blood donations is no exception. The objective of this work was to document the intersectoral work in the management of blood donations in Cuba and to provide theoretical elements that contribute to its improvement. A bibliographic review of the literature on intersectoriality and the processes for the management of blood donations in the country was carried out; For this, works published on Internet sites were consulted, as well as texts and other documents available in repositories of the Infomed web portal network. Intersectoriality is theorized and illustrated as a managerial technology and its use and importance applied in the promotion, capture and recruitment of potential donors and in the organization of blood collections. It is concluded that the use of intersectoriality in the health management of voluntary blood donations, strengthens and distinguishes the Cuban Blood Donation Program in relation to the rest of the world, however, it is necessary to improve the strategic alliances between the health sector and other sectors of organized civil society involved in the activities that comprise this process. [ABSTRACT FROM AUTHOR]

Objectives: To know and explore from convalescent plasma donators' voices the experience in the blood donation process at a social security hospital. Methods: Qualitative study with a phenomenological design. The investigation was carried out in 01 hospitals of the social security of Peru. Semi-structured interviews were carried out. Results: Eleven donors of convalescent plasma were interviewed. The main motivations for donating were being able to contribute to national research and supporting patients affected by COVID-19. Fears focus on the possible risk of contagion within the hospital. Donors emphasised the attention and support of health personnel alongside the donation procedure. The main expectations and suggestions point towards greater dissemination of donation campaigns with special emphasis on safety. Likewise, an improvement in the time of the donation procedure (from enrolment to the extraction of convalescent plasma), and the implementation of friendly spaces to encourage future blood donation campaigns were highlighted. Conclusions: The experience of the convalescent plasma donors was positive. However, improvements must be made in terms of processes and infrastructure to ensure future successful blood donation campaigns. [ABSTRACT FROM AUTHOR]

Introduction: viral hepatitis is a health problem world public, being one of the diseases that affect man. Objective: to know the seroprevalence of the surface antigen of the hepatitis B in blood donors. Methods: a study was conducted retrospective in order to determine the seroprevalence of the hepatitis B virus in 93,440 donors, in the Blood Bank Provincial "Renato Guitart Rosell" of Santiago de Cuba. The term studied ranged from October 2015 to May 2016. Results: there was a slight decrease in the prevalence of hepatitis B surface antigen carriers during the three years studied. The highest reactivity to this marker was in the group aged 41 to 50 years and the male sex predominated. It was found that 0.30% were seropositive for hepatitis B virus. Conclusions: the fulfillment of the established procedures for the adequate selection of the blood donor and the quality and safety of the results in the laboratory determinations of the prevalence of hepatitis B surface antigen carriers, together with the recruitment of voluntary, altruistic and non-remunerated blood donors, has allowed achieving a low seroprevalence in the Province of Santiago de Cuba. [ABSTRACT FROM AUTHOR]

Background and Objectives: Blood donation is suggested to increase the risk of restless legs syndrome (RLS). This study aims to assess the prevalence of RLS in Spanish blood donors and determined its potential correlation with iron metabolism parameters., Materials and Methods: Prospective cohort study of 129 blood donors (54.3% men, 39.44 years ± 11.0) that underwent a physical examination, blood analysis (hemoglobin, ferritin, transferrin saturation index and soluble transferrin receptor) and a RLS screening questionnaire followed by a prospective follow-up study including a clinical phone interview. A multivariate logistic regression model was performed to examine the association between RLS and other variables., Results: Eighty-four (65.1%) participants were repeat blood donors (mean of 2.11 donations/year) at inclusion and 61 (47.4%) at follow-up (mean of 2.09 donations/year). Non-anemic iron deficiency (ferritin < 50 µg/l) was high in women p < 0.001 and in repeat donors (p = 0.003). The prevalence of RLS was 14.1% at inclusion increasing prospectively (19.5%; p = 0.065). On multivariate analysis, gender was the only variable significantly associated with a RLS diagnosis, being higher in women (OR 5.1; 95% CI 1.71-15.3; p = 0.003)., Conclusions: Despite the high prevalence of non-anemic iron deficiency there was no association between ferritin, transferrin saturation index, soluble transferrin receptor concentration values and RLS diagnosis. Gender was associated with RLS diagnosis regardless of other variables., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier España, S.L.U.)

We aimed to determine the prevalence of infection markers in donors of a Peruvian blood bank and to assess whether donor sociodemographic variables are associated with the presence of these markers. An analytical cross-sectional study was carried out in 5942 donors of a blood bank, whose data was collected during 2018. Positivity to human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and HTLV I-II was determined, in addition to syphilis and Chagas disease. The prevalence of HIV was 0.81%; for HBV it was 6.19%; for HCV, 0.12%; for HTLV I-II, 0.66%; for Chagas disease, 2.76% and for syphilis it was 1.73%. Several sociodemographic factors were associated with infection markers positivity. The predominant donation type was non-voluntary (96%) and 53% had history of previous donation. The prevalence of infection markers for HIV, HBV, Chagas disease and syphilis in blood donors was high compared to other countries in the region.

Copyright of Revista de Investigación en Salud VIVE is the property of Revista de Investigacion en Salud VIVE and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objetivo: Evaluar la adaptabilidad del modelo Service Quality (servqual), con el fin de valorar la calidad del servicio en la atención de los donantes de un banco de sangre en la ciudad de Medellín. Metodología: Se llevó a cabo una evaluación psicométrica en 301 donantes de sangre, para determinar la calidad percibida. Se realizaron pruebas de consistencia interna con alpha de Cronbach e índice de discriminación, y se evaluó la validez de contenido de los dos cuestionarios y la estructura factorial, mediante análisis factorial exploratorio. Resultados: El alpha de Cronbach fue de 0,86; en las subescalas de expectativas, 0,87, y en percepciones, 0,77. Se observó una mayor consistencia interna en el cuestionario de expectativas que de percepciones. Aunque se obtuvo una baja consistencia interna en algunas dimensiones, no se afecta la escala de manera global. Conclusión: La escala servqual presenta un adecuado desempeño psicométrico y, por tanto, es útil para evaluar la calidad percibida en la atención en donantes de sangre, siempre y cuando sea abordada de forma unidimensional.

In order to reach high-quality blood-components, it is necessary that people who wish to be a blood donor shall observe a series of conditions that guarantee the least possible risk for the recipient and themselves. According to international standards, an adequate and reliable supply of safe blood can be assured by a stable base of regular, voluntary, unpaid blood donors (altruistic), which is a goal set by the World Health Organization; unfortunately in our country it only represents around 3%, despite the efforts of different institutions. In addition, the population is unaware of risk factors that prevent donating, due to the low culture of this issue. Therefore, it is necessary to implement strategies to disseminate that blood donation is a privilege and donors must have a lifestyle that allows being in a position to be able to carry out this act of solidarity, including having an excellent state of health, adequate dietary hygiene habits, and a lifestyle free of risky behaviors, which includes the non- use of substances as well as a sexual behavior free from situations of exposure to infectious agents transmitted by transfusion. In particular, this point has been controversial, since some groups of the LGBT community have interpreted it as discrimination. The aim of this article is to highlight the difference between the risk factor, particularly for patients who require blood-components for their treatment and sexual behavior. [ABSTRACT FROM AUTHOR]

Copyright of ESPOCH Congresses: The Ecuadorian Journal of S.T.E.A.M. is the property of Knowledge E DMCC and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This study aimed to determine the level of knowledge about blood donation among outpatients from a hospital in Bagua Grande. A descriptive cross-sectional study was conducted from May to July 2019. We developed and applied a structured questionnaire. A total of 244 outpatients were recruited through systematic sampling. Participants obtained a mean number of correct answers of 8.90 (SD: 3.25) points out of 21. Age and educational level were found to be correlated with the score (rho = -0.21; p < 0.001 and rho = 0.38; p < 0.001, respectively). Place of origin and occupation affected the score (p < 0.001). We found a low level of knowledge in the studied population, but this would not be related to previous history of donation. Interventions to improve blood donation should not only focus on providing knowledge, since other factors would be more related to this result. [ABSTRACT FROM AUTHOR]

In 2022, 2 years on from the start of the pandemic, the Instituto Mexicano del Seguro Social (IMSS, Mexican Institute for Social Security) has been reorganizing its services at full, out of which blood banks play a key role. In addition, on June 14 it is celebrated the World Blood Donor Day by the World Health Organization and this year Mexico was the host country for the celebration. Therefore, it is important to highlight the work carried out in blood banks, ranging from their main activity, which is the recruitment of blood donors and the blood components production, to the different interventions they have in the field of transplantation, diseases emerging diagnosis and the development of new therapeutic modalities, such as, for example, cell therapy. [ABSTRACT FROM AUTHOR]

Objetivo: Describir las características de los donantes voluntarios de sangre en las Universidades de Neiva Huila, durante las promociones realizadas por el banco de sangre del Hospital Universitario Hernando Moncaleano Perdomo en convenio con la Universidad Surcolombiana durante el período 2013-2017. Materiales y métodos: Estudio observacional descriptivo de corte transversal, para los periodos de enero 2013 a diciembre 2017, basado en fuentes secundarias suministradas por la Red Nacional de Bancos de Sangre, a través del Banco de Sangre del Hospital Universitario Hernando Moncaleano Perdomo de Neiva. Se realizó un muestreo por conveniencia, que cumplieran con criterios de inclusión y exclusión definidos para el estudio. Las variables que se analizaron fueron grupos de edad, género, grupo sanguíneo ABO y factor Rh. Resultados: Durante el periodo de estudio se realizaron 6.547 donaciones de sangre voluntarias, de las cuales el 85,5% (I.C 95%: 84,6-86,3) fueron ocasionales y el 14,5% (I.C 95%: 13,6-15,6) habituales. Quienes más donaron fueron hombres entre 19 y 29 años. Se evidencio que el factor Rh positivo y el grupo sanguíneo O+, fueron los que más prevalecieron en la población donante en el 98,5% y 61,6% respectivamente. Conclusión: Los donantes voluntarios habituales son principalmente hombres entre 19 y 29 años, con grupo sanguíneo O y Rh +, dado que los hombres pueden realizar un mayor número de donaciones en comparación con las mujeres. Palabras Clave: Características de la población, Donantes de sangre, Sistema del grupo sanguíneo ABO, Sangre, Factor Rh.

Arboviruses represent a threat to transfusion safety for several reasons: the presence of vectors and the notification of autochthonous cases in our region, the recent increase in the number of cases transmitted through blood and/or blood component transfusion, the high prevalence rates of RNA of the main arboviruses in asymptomatic blood donors, and their ability to survive processing and storage in the different blood components. In an epidemic outbreak caused by an arbovirus in our region, transfusion centres can apply different measures: reactive measures, related to donor selection or arbovirus screening, and proactive measures, such as pathogen inactivation methods. The study of the epidemiology of the main arboviruses and understanding the effectiveness of the different measures that we can adopt are essential to ensure that our blood components remain safe., (Copyright © 2024 Elsevier España, S.L.U. All rights reserved.)

We aimed to determine the prevalence of infection markers in donors of a Peruvian blood bank and to assess whether donor sociodemographic variables are associated with the presence of these markers. An analytical cross-sectional study was carried out in 5942 donors of a blood bank, whose data was collected during 2018. Positivity to human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and HTLV I-II was determined, in addition to syphilis and Chagas disease. The prevalence of HIV was 0.81%; for HBV it was 6.19%; for HCV, 0.12%; for HTLV I-II, 0.66%; for Chagas disease, 2.76% and for syphilis it was 1.73%. Several sociodemographic factors were associated with infection markers positivity. The predominant donation type was non-voluntary (96%) and 53% had history of previous donation. The prevalence of infection markers for HIV, HBV, Chagas disease and syphilis in blood donors was high compared to other countries in the region. [ABSTRACT FROM AUTHOR]

Objective: To assess the reproducibility and validity of the scale of perceived quality in donors from a blood bank in the city of Medellín. Methods: Psychometric evaluation in 301 blood donors through internal consistency with Cronbach's alpha and discrimination index. Content validity of the polls and factorial structure were evaluated by means of exploratory factor analysis. Results: Cronbach's alpha was 0.86. For the expectations subscales, 0.87 and in perceptions 0.77. A greater internal consistency was observed in the poll of expectations rather than in that of perceptions. Although low internal consistency was obtained in some dimensions, this does not affect the scale globally. The use of the instrument should be approached in a unidimensional way. Conclusion: The servqual scale presents an adequate psychometric performance and, therefore, is useful to assess the perceived quality of care in blood donors in the Colombian context, as long as it is approached in a unidimensional way. [ABSTRACT FROM AUTHOR]

Introducción. La infección por Toxoplasma gondii puede presentarse en los humanos con un amplio rango de manifestaciones que van desde el estado asintomático hasta la enfermedad grave, según el estado inmunológico del individuo. Los mecanismos de transmisión incluyen la transfusión sanguínea, pero poco se sabe sobre la frecuencia del parásito en los bancos de sangre de Colombia. Objetivo. Determinar la prevalencia de la infección con T. gondii en donantes de un banco de sangre de Cúcuta mediante técnicas de diagnóstico serológico y molecular. Materiales y métodos. Se determinaron los anticuerpos IgG e IgM contra T. gondii mediante un inmunoensayo en suero en 348 donantes. Se determinó la frecuencia de ADN de T. gondii utilizando la reacción en cadena de la polimerasa (PCR) en sangre total de donantes seropositivos y se analizaron las variables de interés con base en la información obtenida durante la selección de donantes. Resultados. De los 348 donantes participantes, 134 (38,5 %) presentaron anticuerpos IgG contra T. gondii; dos (0,6 %) de ellos presentaron tanto IgG como IgM y, en dos (1,5 %), se detectó ADN del parásito en la sangre. Un análisis bivariado evidenció una asociación entre la seropositividad para T. gondii y tener más de 26 años de edad (p=0,020). Conclusiones. La prevalencia de la infección con T. gondii encontrada en los donantes de sangre sugiere una exposición significativa al agente, la cual adquiere relevancia al detectarse la parasitemia.

Abstract: Studies performed on blood units allow the detection of transfusion-transmissible infections (TTI) through the presence of the etiological agent or the antibodies generated by the donor's immune system against infectious agents. The objective of the study was to determine the prevalence of any TTI in blood donors who attended the Dr. Egidio Montesinos Hospital in the city El Tocuyo during the years 2010-2017. For these 6440 sera were analyzed by the ELISA test of different biotechnology companies, of which 481 cases were reactive to different infections, which gives 7.47% of prevalence to any TTI. The specific results were stratified by TTI, year, sex and origin of the infected donor, obtaining a seroprevalence of 0.66% for HBsAg, for anti-HBc (5.34%), for HCV (0.17%), for infection by Trypanosoma cruzi (0.42%), for infection by Treponema pallidum (0.61%) and for HIV (0.26%). No reactive case was found for HTLV. The population studied can be considered as high risk to transmit HBV given that in this area of influence high figures of their biomarkers are presented with respect to the average of the region, subregion and country. Resumen: Los estudios realizados a las unidades de sangre permiten detectar las infecciones transmisibles por transfusión (ITT) a través de la presencia del agente etiológico o los anticuerpos generados por el sistema inmunológico del donante contra los agentes infecciosos. El objetivo del estudio fue determinar la prevalencia de cualquier ITT en los donantes de sangre que acudieron al Hospital Dr. Egidio Montesinos de la ciudad de El Tocuyo durante los años 2010-2017. Se analizaron 6440 sueros mediante la prueba ELISA de diferentes compañías biotecnológicas, de los cuales 481 casos fueron reactivos a diferentes infecciones lo que arroja un 7,47% de prevalencia a cualquier ITT. Los resultados específicos se estratificaron por ITT, año, sexo y procedencia del donante infectado consiguiéndose una seroprevalencia de 0,66% para el HBsAg, para el anti-HBc (5,34%), para VHC (0,17%), para infección por Trypanosoma cruzi (0,42%), para infección por Treponema pallidum (0,61%) y para VIH (0,26%). No se encontró ningún caso reactivo para HTLV. La población estudiada puede ser considerada como de alto riesgo para transmitir el VHB dado que en esta zona de influencia se presentan cifras elevadas de sus biomarcadores respecto al promedio de la región, de la subregión y del país.

Introducción. La sífilis es una enfermedad de interés en salud pública por sus elevadas tasas de morbilidad y mortalidad. Objetivo. Determinar la serorreacción y la seroprevalencia de sífilis según las variables sociodemográficas de los donantes de un banco de sangre del distrito de Barranquilla, Colombia, durante 2015 y 2016. Materiales y métodos. Se hizo un estudio descriptivo de corte transversal basado en los resultados de las pruebas treponémicas y no treponémicas. Se analizaron las variables sociodemográficas de la población estudiada y se hizo un análisis univariado en el que se determinaron las frecuencias absoluta y relativa de cada una de las variables categóricas. Se determinó la serorreacción a Treponema pallidum y la prevalencia de la infección activa. Se utilizó la prueba de ji al cuadrado de Pearson para evaluar las diferencias entre las proporciones. Resultados. Se encontró una serorreacción de 1,86 % para la infección previa con T. pallidum y una prevalencia de 0,93 % para la infección activa, las cuales fueron más altas en hombres adultos y en adultos mayores, viudos, desempleados y personas residentes en otros municipios del departamento de Atlántico diferentes de Barranquilla y su área metropolitana. Se encontró una asociación significativa entre la sífilis y las variables de sexo y ocupación. Conclusión. Se registró una serorreacción elevada a T. pallidum en donantes de sangre, comparada con el promedio nacional. Se encontró asociación entre la sífilis, y las variables sociodemográficas de sexo y ocupación, principalmente.

La donación de sangre es un procedimiento muy común en medicina, por eso tiene relevancia el estudio de las complicaciones frecuentes en los donantes y en especial las asociadas con la ferropenia. El procedimiento reporta beneficios tanto por la utilidad futura del producto como por los efectos favorables para la salud del donante; sin embargo, se han descrito complicaciones recurrentes derivadas tanto de la extracción de sangre total como de sus componentes por separado. En este artículo de revisión se encuentra la información relacionada con los factores de riesgo asociados con esta práctica y las principales complicaciones que pueden aparecer como es la depleción de hierro, con el fin de ilustrar al lector sobre los factores predisponentes en donantes iniciales y habituales. Se concluye que las reacciones más frecuentes son las vasovagales y algunas otras que pueden conllevar a síntomas indeseados, pero es la disminución de los niveles de hierro una de las complicaciones más alarmantes. Hay evidencia de factores como sexo, edad, nivel socioeconómico, dieta y tipo de sangre que favorecen la probabilidad de desarrollar complicaciones por deficiencia de hierro en los donantes.

Introduction: Chagas' disease is the leading cause of infectious myocarditis worldwide. This infection caused by Trypanosoma cruzi is usually life-long and asymptomatic; however, the third part of infected people can develop severe or even fatal cardiomyopathy. As the parasitemia in the chronic phase is both low-grade and intermittent, T. cruzi infection is principally detected by serology, although this method has sensitivity and specificity limitations. Objective: To determine the level of agreement between serologic and molecular tests in 658 voluntary blood donors from six provinces in the Colombian department of Santander. Materials and methods: We evaluated an array of diagnostic technologies by cross-section sampling performing a serological double diagnostic test for T. cruzi antibody detection (Chagas III ELISA™, BiosChile Group, and ARCHITECT Chagas CMIA™, Abbott), and DNA detection by polymerase chain reaction (PCR). We collected the demographic, clinical, and epidemiological information of participants. The sample size was calculated using Epidat™ and the statistical analysis was done with Stata 12.1™. Results: PCR was six times more sensitive in detecting T. cruzi infection than ELISA/CMIA with prevalence values of 1.8% (12/658) and 0.3% (2/658), respectively, and kappa=0.28 (95%CI: -0.03 - 0.59). In contrast, serology showed a sensitivity of 16.7% (95%CI: 2.09 - 48.4) and a specificity of 100% (95%CI: 99.4 - 100). All seropositive samples were found to be positive by PCR. Conclusions: The implementation of PCR as a complementary method for screening donors could reduce the probability of false negative and the consequent risk of transfusional-transmission of Chagas' disease, especially in endemic regions. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Nursing UFPE / Revista de Enfermagem UFPE is the property of Revista de Enfermagem UFPE and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Bioetica is the property of Conselho Federal de Medicina and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Research objective is to classify seropositive donors according to origin, age, sex and occupation and to determine the prevalence of infection. It was a descriptive, nonexperimental, cross-sectional study. Data recorded from the Donors Book of the Blood Bank of the Red Cross of Guayaquil, during the years 2016-2018, were analyzed. Patient seropositivity was checked for IgG antibodies to Trypanosoma cruzi using Enzyme-Linked ImmunoSorbent Assay (ELISA), Indirect Hemagglutination (HAI) and Indirect Immunofluorescence (IFI). 315 seropositive donors with the highest prevalence for 2017, from the urban area (n = 105; 76.64%) were counted. In rural areas, the highest prevalence was recorded in 2016 (n = 34; 33.33%). The age group most compromised was the range of 18-22 years, corresponding to the male sex (n=68, 21,58%; n= 103, 32,69%; n= 53, 16,68%). The main occupation for 2018 corresponded to students (43.47%). For 2017, household chores (32.35%) and for 2016, elementary occupations (13.82%), such as selling goods on the streets, agriculture, fishing, construction of public works and manufacturing industries. The infection prevalence for 2016, 2017 and 2018 was 0.038%, 0.028% and 0.051% respectively. [ABSTRACT FROM AUTHOR]

Copyright of Investigaciones ANDINA is the property of Fundacion Universitaria del Area Andina and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Paulista de Enfermagem is the property of Universidade Federal de Sao Paulo, Escola Paulista de Enfermagem and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

El objetivo de esta investigación fue estimar la seropositividad de VIH y factores asociados en donantes de un banco de sangre de la ciudad de Medellín - Colombia, 2005 - 2018. Se realizó un estudio transversal en 166 603 donantes del banco de Sangre de la Escuela de Microbiología de la Universidad de Antioquia. Las estimaciones se basaron en proporciones y razones de odds con sus intervalos de confianza del 95 %. La mayoría de donantes fueron del Valle de Aburrá, 50,2 % hombres, 65,4 % altruistas, 59,3 % de primera vez y 81,2 % captados fuera de las instalaciones del Banco. La seropositividad general de VIH fue 0,275 % (IC 95 %=0,25-0,30), en las frecuencias específicas fue del 0,324 % en hombres y 0,224 % en mujeres; 0,299 % en donantes con edad entre 18 - 40 años, 0,212% en los de 41 - 65 años, y del 0,333 % en los de primera vez; 0,213 % en lo no repetitivos y 0,149 % en los donantes repetitivos. Se concluye que la seropositividad de la infección fue similar en comparación con investigaciones previas, con un descenso importante desde el 2013. El riesgo de infección fue estadísticamente mayor en los hombres, los menores de 40 años y donantes de primera vez. Esto es importante para conocer la línea base y evaluar acciones de prevención en la población de estudio, orientar estudios etiológicos y mejorar políticas de hemovigilancia.

Introduction: Blood donation saves lives, thus blood safety is the most important part of the entire process. Demographic location leads to specific causes of deferral. Living in high Andean areas would produce hematological adaptive changes. It is for this reason that it is important to know the causes of rejection and thus be able to reorient the blood donation promotion programs. Objective: To determine the causes of rejection in blood donors of a hospital in southern Peru at 3825 m.a.s.l. Methods: A cross-sectional, retrospective study was carried out on the causes of rejection prior to the donation of possible blood donors from the Hospital III EsSalud; Juliaca. The records of pre-donors that were rejected were analyzed, from January 2014 to December 2018. The data was analyzed in the STATA v. 14 using frequency distribution tables and figures. Results: From the possible selected pre-donors (4,057), 1,699 (41.87%) were women and 2,358 (58.13%) were men. 1458 (41.87%) were deferred, men had the highest rejection rate 882 (60.49%) compared to women 576 (39.51%). Polyerythrocythemia was the most frequent cause of rejection 669 (45.8%). Conclusions: The rejection rate was moderate, with high and low hematocrit being the main causes.

Introducción: Factores relacionados con la donación de sangre según diversos estudios realizados en la actualidad, nos han evidenciado la importancia que tienen para que la población se abstenga a realizar donaciones. Por tal motivo es preciso identificar los factores que influyen en la donación de sangre en la ciudad de Santo Domingo. Métodos: Se empleó un enfoque cuantitativo, con un diseño de tipo transversal, utilizando un muestreo por cuotas, incluyó 384 personas de la ciudad de Santo Domingo, se utilizó la encuesta y como instrumento un cuestionario, para los análisis estadísticos se utilizó el programa computacional SPSS. Resultados: Los datos obtenidos de esta investigación demostraron que el 97% de los encuestados han escuchado sobre la donación de sangre, un 58% creen que la sangre tiene un propósito comercial. El 23% ha donado sangre, un 57,8% donaría de manera voluntaria. El 71% considera importante el temor a la extracción, un 89% el mal estado de salud, un 78% la desconfianza hacia la esterilidad del material y el 60% no saber dónde donar. El 15% de la población es susceptible a creencias y mitos con relación a la donación de sangre. Conclusiones: En el estudio realizado en la ciudad de Santo Domingo se evidencio que la donación de sangre no está ligada a creencias y mitos; pero existen cierto tipo de factores que generan un déficit de este líquido vital en los bancos de sangre.

Fundamento: existe una subvaloración de la significación de la lipemia como indicador de problema de salud en individuos que acuden a donar sangre. Objetivo: estimar la prevalencia de factores de riesgo para enfermedades cardiovasculares y medir su asociación con la presencia de lipemia en donantes de sangre. Métodos: se realizó un estudio descriptivo, analítico de casos y controles con 33 y 66 pacientes respectivamente realizado en el Banco Provincial de Sangre de Cienfuegos, desde el 1ro de marzo hasta el 31 de octubre del año 2015. Los casos fueron identificados como positivos en la prueba de lipemia predonación y los controles, con prueba negativa. Se consideraron las variables: donantes aptos y no aptos, lipemia, edad, sexo, hábito de fumar, diabetes mellitus, hipertensión arterial, cintura abdominal, índice de masa corporal, triglicéridos, colesterol total y sus fracciones. Se calculó el coeficiente de correlación de Pearson para medir asociación entre variables con un intervalo de confianza del 95 %, Chi cuadrado X2 y Odds Ratio. Resultados: la lipemia representó el 30,6 % de las causas de rechazo en los donantes de sangre. Los principales factores de riesgo encontrados fueron lipoproteínas de baja densidad disminuida, lipoproteínas de baja densidad aumentada, obesidad, hipertrigliceridemia, hábito de fumar e hipertensión arterial. Las variables con valores más altos de los Odds Ratio fueron lostriglicéridos, lipoproteínas de baja densidad colesterol, cintura abdominal y el índice de masa corporal. Conclusiones: los donantes con plasma turbio tienen un perfil cardiometabólico más favorable para padecer enfermedades cardiovasculares que aquellos con prueba de lipemia negativa.

Copyright of Saúde Coletiva is the property of MPM Comunicacao and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The objective of this study was to estimate the seropositivity of HIV and associated factors in donors of a blood bank in the city of Medellín- Colombia, 2005 - 2018. A cross-sectional study in 166 603 donors of the Blood Bank of the School of Microbiology. Estimates were based proportions and odds ratios with 95% confidence intervals. The majority of donors were from the Aburrá Valley, 50.2% men, 65.4% altruistic, 59.3% first time and 81.2% received outside the blood bank. The general seropositivity of HIV was 0.275% (95% CI = 0.25-0.30), the specific proportions were 0.324% in men and 0.224% in women; 0.299% in donors with 18-40 years old and 0.212% in the group of 41-6540 years old, and 0.333% in donors of first-time, 0.213% in non-repetitive and 0.149% in repetitive donors. The conclusion was that the seropositivity of the infection was similar in comparison with previous investigations, with a significant decrease since 2013. The risk of infection was statistically higher in men, under 40 years and first-time donors. All this takes is important to know the baseline and evaluate prevention actions in the study population, guide etiological studies, and improve hemovigilance policies. [ABSTRACT FROM AUTHOR]