1. A systematic review on current approaches in bat virus discovered between 2018 and 2022.
- Author
-
Mo Y, Lim LS, and Ng SK
- Subjects
- Animals, High-Throughput Nucleotide Sequencing, Viruses classification, Viruses genetics, Viruses isolation & purification, Genome, Viral, RNA Viruses genetics, RNA Viruses classification, RNA Viruses isolation & purification, Phylogeny, DNA Viruses genetics, DNA Viruses classification, DNA Viruses isolation & purification, Virus Diseases virology, Virus Diseases veterinary, Viral Zoonoses virology, Chiroptera virology, Metagenomics methods
- Abstract
Zoonotic viruses are widely seen as the primary threat for future pandemics. Bats are the most diverse group of mammals, with more than 1400 species distributed across most habitats on Earth. So far, 31 known virus families were associated with bats, although the understanding of most viruses were insufficient. Continuous efforts to discover, understand and monitor these bats viruses, is thereby an area of public health interest. This systematic review was designed to catalogue publications reporting novel bat virus discoveries within PubMed, SCOPUS, and Web of Science databases, within a 5-year period from 2018 to 2022. Various experimental parameters, including sampling locations, methodology, bat species diversity, similarity to known viruses, species demarcation of new viruses, and genomic sequencing strategies, were extracted from 41 publications and analyzed. In total, 72 novel viruses from 19 virus families were identified between 2018 and 2022, particularly from Genomoviridae (DNA viruses) and Coronaviridae (RNA viruses). That said, only a limited number of bat families featured extensively despite noticeable shift towards next generation sequencing methods and metagenomics pipeline for virus identification across different sampling methods. This review aims to provide a comprehensive analysis of the global efforts made over the past five years to identify and characterize emerging viruses in bat species, and to provide a detailed overview of the current technologies and methodologies used in these studies., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF