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Mesoporous ceramic materials used in applications such as catalysis, filtration, or sensing, are usually hierarchically structured. Thereby, their structural hierarchy is often inherently related to the manufacturing methods and cannot be independently locally designed along all length scales. This study combines light‐based additive manufacturing and bottom‐up light‐induced self‐assembly (LISA) sol‐gel chemistry to engineer hierarchically structured porous silica from the nanoscale to the macroscopic object geometry. A LISA‐based printing solution that enables printing of ordered mesoporous silica with geometrically complex shapes by using a commercially available digital light processing (DLP)‐based 3D printer is presented. This approach exploits the self‐assembly process of block copolymer mesopore templates, such as Pluronic P123, and hydrolysis and condensation of silica precursors upon irradiation in the 3D printer to shape mesoporous silica objects. Furthermore, different resins are added to the LISA solution to print 3D silica‐resin objects. Mesoporous silica objects up to 10 mm in size, consisting of ordered mesopores with diameters around 5 nm and having high specific surface areas of ≈400 m2 g−1 are successfully printed with a fast and easy post‐processing. [ABSTRACT FROM AUTHOR]

Purpose: The aim of the study was to establish and propose the utilisation of paediatric National Diagnostic Reference Levels (DRLs) for dose length product (DLP) and volume computed tomography dose index (CTDIvol) for most commonly routine computed tomography (CT) for paediatric examinations. Method: These were based on the most commonly used routine brain protocol, the chest protocol and the abdominal-Pelvis protocol for head, chest and abdominal scans respectively. 200 images which met the selection criterion were used for the analysis. Results: The measured median and 75th percentile CTDIVOL of head were 14.9 and 15.5 mGy, chest was 1.4 and 1.7 mGy, abdomen-pelvis were 5.1 and 15.3 mGy respectively. While DLP for head were 457 and 498 mGy-cm, chest was 13 and 14 mGy-cm, abdomen-pelvis were 26 and 29 mGy-cm. Similar trends were observed in aged 6.-10y and 11-16y. Conclusion: The study recommends the use of the established CTDIVOL and DLP as reference values for clinical application in Ghana. [ABSTRACT FROM AUTHOR]

The rapid development of additive manufacturing techniques enables the preparation of SiC ceramics with complex configurations; however, the high sintering temperature and defects-control are still great challenges during processing. Thus, SiC ceramics were prepared by digital light processing followed by liquid phase sintering using Al 2 O 3 –Y 2 O 3 additives in this study. The photopolymerization of the SiC slurry, microstructures and mechanical properties of the sintered ceramics were investigated. The Al 2 O 3 –Y 2 O 3 additives enhanced the curing ability of the photosensitive SiC slurries by reducing the absorbance and scattering of UV light. The liquid phase accelerated the densification of the ceramics by particles rearrangement and interfacial bonding. Thus, the flexural strength of the ceramics increased from 41.0 MPa to 62.8 MPa with sintering temperature increasing. [ABSTRACT FROM AUTHOR]

Abstract Background This work aims to investigate existing methodologies that have been used to establish diagnostic reference levels (DRLs) for common computed tomography angiography (CTA) examinations in adult patients by analyzing published national and local DRL studies. A detailed search through Science Direct, Web of Science, EBSCO host, PubMed–Medline, and Google Scholar was conducted. The preferred reporting items for systematic review and meta-analyses methodology was also used to evaluate the selected articles. Studies were selected via the PICOS method and included only DRL studies established for CTA examinations. Case studies, posters, reviews, and meta-analyses were excluded. The literature review identified 21 publications, 15 proposed a national DRL survey, and 6 studies with local (facility) data. Results A noticeable variation in DRL quantities for the same CTA procedures was noted among studies. Several factors contributed to this variability, including the methodologies used for establishing CTA DRLs, variations in scanning protocols, number of scanning phases, and scanner type. Conclusion There is a need for a global standardization for DRL establishment methods aligned with recent recommendations from prominent international radiation protection bodies to facilitate accurate comparisons of radiation dose metrics both between and within CT imaging facilities.

In this study, the variant effects of alumina and graphene reinforcing nanoparticle percentages on the tensile and wear properties of the nanocomposites, produced using digital light processing (DLP), were determined by employing SEM images of fracture and worn surfaces to introduce a hybrid (alumina + graphene)/PLA nanocomposite with desirable wear and mechanical properties. With the addition of alumina up to 2 wt%, the tensile strength was initially decreased exhibiting a rapid brittle fracture over the flat fracture surface. However, with a continued increase in the amount of reinforcing particles, the tensile strength eventually increased by 16% compared to the pure resin sample at 8 wt% of alumina while changing the fracture mode with plenty of cleavages accompanied by crack deflections. The specific wear rate in the 8 wt% alumina sample decreased by almost 62% compared to the pure resin sample. Graphene caused a significant drop in tensile strength due to the generation of cavities and porosities around the graphene agglomerates, but it greatly improved the wear properties, with the specific wear rate decreasing by almost 77% at just 1 wt%. Then hybrid nanocomposites of alumina and graphene reinforcements were produced with the aim of optimal tensile and wear properties. The 0.5% graphene +3.5% alumina improved the wear resistance and provided moderate tensile properties; however, the 1% graphene +3% alumina could not increase the wear resistance due to the weakening of graphene plates sticking to the polymer substrate.

Modern technologies like quantum and cloud computing have reshaped computing, offering immense power and scalability. While beneficial, they also challenge the security of traditional cryptographic systems. Quantum computing threatens RSA and ECC with algorithms like Shor's algorithm, which can accelerate computations exponentially. This risks exposing these systems to attacks, necessitating quantum-resistant cryptography. Cloud computing poses data security concerns, requiring robust cryptographic mechanisms and access controls. Lattice-based cryptography, leveraging problems like the Short Integer Solution (SIS), emerges as a solution. This paper presents a novel quantum-resistant public key encryption scheme based on ElGamal and SIS, ensuring security against quantum and classical threats in modern cryptographic environments. [ABSTRACT FROM AUTHOR]

Digital light processing (DLP) three‐dimensional printing has the advantages of both high printing resolution and efficiency and has been used to manufacture high‐precision, small, and complex shaped ceramic parts. One of the challenges of DLP is to develop photosensitive ceramic slurries with high solid content and low viscosity, especially for non‐oxide ceramics such as silicon nitride due to the dispersion and light absorption problem. This study mainly explores the dispersibility of silicon nitride in ultraviolet (UV)‐cured resins and the photocured properties of the slurry. Rheological measurements were utilized to characterize and screen different dispersants in the resin. It was found that DISPERMP is an effective dispersant. In order to improve the curing depth of Si3N4 photosensitive paste, the surface of silicon nitride powder was treated by oxidation, and organic compounds with different refractive indices were also introduced to increase the light penetration depth. It was found that glycerol with a refractive index of 1.474 resulted in the greatest improvement in the curing depth of Si3N4 photosensitive paste. Finally, a proposed slurry composition was developed to successfully print silicon nitride ceramics through UV‐curing molding technology. [ABSTRACT FROM AUTHOR]

The challenges of replicating the complex mechanical and structural diversity of natural tissues in vitro by leveraging multi‐material digital light processing (DLP) bioprinting are addressed. This technique utilizes PEGDA‐AAm bio‐ink to develop multi‐component, cell‐laden hydrogel constructs with varying moduli. These constructs not only possess heterogeneous mechanical properties but also feature complex architectures and precisely engineered surface microstructures. The hydrogel microfluidic chips are successfully fabricated with perfusable microchannels, embedding various cell types within the matrix. This approach enables the bioprinting of intricate cell‐laden structures with unique surface topologies, such as spiral grooves and triply periodic minimal surfaces (TPMS), which effectively influence cell alignment, spreading, and migration. By integrating various cell‐laden PA hydrogels, the diverse mechanical moduli of biological tissues, including bone, liver lobules, and vascular networks are replicated. This technique ensures high‐fidelity differentiation between cell types and regions. These findings provide valuable insights into the impact of substrate modulus and structure on cell behavior, underscoring the potential of multi‐component, multi‐modulus hydrogel constructs in creating sophisticated structures with custom‐tailored mechanical properties. This study significantly advances the field by demonstrating the feasibility and effectiveness of multi‐material DLP bioprinting in developing complex, functionally relevant tissue models for tissue engineering and regenerative medicine. [ABSTRACT FROM AUTHOR]

Glypicans are closely associated with organ development and tumorigenesis in animals. Dally-like (Dlp), a membrane-bound glypican, plays pivotal roles in various biological processes in Drosophila. In this study, we observed that an excess of Dlp led to the malformation of legs, particularly affecting the distal part. Accordingly, the leg disc was shrunken and frequently exhibited aberrant morphology. In addition, elevated Dlp levels induced ectopic cell death with no apparent cell proliferation changes. Furthermore, Dlp overexpression in the posterior compartment significantly altered Wingless (Wg) distribution. We observed a marked expansion of Wg distribution within the posterior compartment, accompanied by a corresponding decrease in the anterior compartment. It appears that excess Dlp guides Wg to diffuse to cells with higher Dlp levels. In addition, the distal-less (dll) gene, which is crucial for leg patterning, was up-regulated significantly. Notably, dachshund (dac) and homothorax (hth) expression, also essential for leg patterning and development, only appeared to be negligibly affected. Based on these findings, we speculate that excess Dlp may contribute to malformations of the distal leg region of Drosophila, possibly through its influence on Wg distribution, dll expression and induced cell death. Our research advances the understanding of Dlp function in Drosophila leg development. [ABSTRACT FROM AUTHOR]

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Objective: This study investigates the correlation between patient body metrics and radiation dose in abdominopelvic CT scans, aiming to identify significant predictors of radiation exposure. Methods: Employing a cross-sectional analysis of patient data, including BMI, abdominal fat, waist, abdomen, and hip circumference, we analyzed their relationship with the following dose metrics: the CTDIvol, DLP, and SSDE. Results: Results from the analysis of various body measurements revealed that BMI, abdominal fat, and waist circumference are strongly correlated with increased radiation doses. Notably, the SSDE, as a more patient-centric dose metric, showed significant positive correlations, especially with waist circumference, suggesting its potential as a key predictor for optimizing radiation doses. Conclusions: The findings suggest that incorporating patient-specific body metrics into CT dosimetry could enhance personalized care and radiation safety. Conclusively, this study highlights the necessity for tailored imaging protocols based on individual body metrics to optimize radiation exposure, encouraging further research into predictive models and the integration of these metrics into clinical practice for improved patient management.

The aim of this study is to investigate the influence of printing material, build angle, and artificial aging on the accuracy of SLA- and DLP-printed occlusal devices in comparison to each other and to subtractively manufactured devices. A total of 192 occlusal devices were manufactured by one SLA-printing and two DLP-printing methods in 5 different build angles as well as milling. The specimens were scanned and superimposed to their initial CAD data and each other to obtain trueness and precision data values. A second series of scans were performed after the specimens underwent an artificial aging simulation by thermocycling. Again, trueness and precision were investigated, and pre- and post-aging values were compared. A statistically significant influence was found for all main effects: manufacturing method, build angle, and thermocycling, confirmed by two-way ANOVA. Regarding trueness, overall tendency indicated that subtractively manufactured splints were more accurate than the 3D-printed, with mean deviation values around ±0.15 mm, followed by the DLP1 group, with ±0.25 mm at 0 degree build angle. Within the additive manufacturing methods, DLP splints had significantly higher trueness for all build angles compared to SLA, which had the highest mean deviation values, with ±0.32 mm being the truest to the original CAD file. Regarding precision, subtractive manufacturing showed better accuracy than additive manufacturing. The artificial aging demonstrated a significant influence on the dimensional accuracy of only SLA-printed splints. [ABSTRACT FROM AUTHOR]

Skin aging is a complex physiological process, in which cells and the extracellular matrix (ECM) interreact, which leads to a change in the mechanical properties of skin, which in turn affects the cell secretion and ECM deposition. The natural skin microrelief that exists from birth has rarely been taken into account when evaluating skin aging, apart from the common knowledge that microreliefs might serve as the starting point or initialize micro-wrinkles. In fact, microrelief itself also changes with aging. Does the microrelief have other, better uses? In this paper, owing to the fast-developing 3D printing technology, skin wrinkles with microrelief of different age groups were successfully manufactured using the Digital light processing (DLP) technology. The mechanical properties of skin samples with and without microrelief were tested. It was found that microrelief has a big impact on the elastic modulus of skin samples. In order to explore the role of microrelief in skin aging, the wrinkle formation was numerically analyzed. The microrelief models of different age groups were created using the modified Voronoi algorithm for the first time, which offers fast and flexible mesh formation. We found that skin microrelief plays an important role in regulating the modulus of the epidermis, which is the dominant factor in wrinkle formation. The wrinkle length and depth were also analyzed numerically for the first time, owing to the additional dimension offered by microrelief. The results showed that wrinkles are mainly caused by the modulus change of the epidermis in the aging process, and compared with the dermis, the hypodermis is irrelevant to wrinkling. Hereby, we developed a hypothesis that microrelief makes the skin adaptive to the mechanical property changes from aging by adjusting its shape and size. The native-like skin samples with microrelief might shed a light on the mechanism of wrinkling and also help with understanding the complex physiological processes associated with human skin. [ABSTRACT FROM AUTHOR]

Objective: The objective of the present study was to enhance the bioavailability of cannabidiol (CBD) using 3D Digital Light Processing (DLP)-printed microneedle (MN) transdermal drug delivery system. Methods: CBD MN patch was fabricated and optimized using 3D DLP printing using CBD (8% w/v), Lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) (0.49% w/v), distilled water (20% w/v), and poly (ethylene glycol) dimethacrylate 550 (PEGDAMA 550) (up to 100% w/v). CBD MNs were characterized for their morphology, mechanical strength, in vitro release study, ex vivo permeation study, and in vivo pharmacokinetic (PK) profile. Key findings: Microscopic images showed that sharp CBD MNs with a height of ~800 μm, base diameter of ~250 μm, and tip with a radius of curvature (RoC) of ~15 μm were successfully printed using optimized printing parameters. Mechanical strength studies showed no significant deformation in the morphology of CBD MNs even after applying 0.5N/needle force. Ex vivo permeation study showed significant (P <.0001) permeation of CBD in the receiving media as compared to CBD patch (control). In vivo PK study showed significantly (P <.05) enhanced bioavailability in the case of CBD MN patch as compared to CBD subcutaneous inj. (control). Conclusion: Overall, systemic absorption of CBD was significantly enhanced using 3D-printed MN drug delivery system. Graphical Abstract [ABSTRACT FROM AUTHOR]

Currently, ceramic dentures are mainly obtained by using computer-assisted cutting block of material to obtain the shape as the removing a model of patient's mouth. Followed by immersion coloring, porcelain stacking, and sintering to obtain dentures similar to a patients' tooth, this is a large-loss and complex process. In this study, 16 standard tooth samples were successfully reduced by adding Fe 2 O 3 , Pr 6 O 10 , Er 2 O 3 , and MnO 2. After the colorful ceramic powder and photosensitive resin were configured into a slurry, a close to the sample tooth dentures was successfully prepared using digital light processing (DLP). The flexural strength and compressive strength of the ceramic specimens prepared by this method reached 821.01 ± 51.72 MPa and 2.67 GPa ± 0.22 MPa. To verify the biosafety of the prepared ceramics, we performed an in vitro biological evaluation of rat fibroblasts (L929). The resulting showed that the extracts of the prepared ceramic teeth had good biosafety, and the cells could also attach to the surface of the prepared ceramics. Hemolysis experiments confirmed good blood compatibility. Thus, our results show that DLP-printed standard tooth-colored ceramic dentures have good mechanical properties and biocompatibility, and can provide a solution to patients seeking quick access to aesthetic dentures. We present a strategy for the development of standard tooth-colored, high-precision, high-mechanical-property and highly biocompatible ceramic dentures based on DLP light-curing printing technology. Through a large number of experiments to find the law of color adjustment, and achieved the reduction of 16 kinds of tooth color. Adjusting the printing parameters, high precision printing was realized. The samples are structurally stable after sintering and have excellent mechanical properties. Through CCK-8, hemolysis rate, live/dead cell staining, cell adhesion and cytoskeletal staining tests, the prepared denture showed excellent biocompatibility. [Display omitted] [ABSTRACT FROM AUTHOR]

In an evolving cybersecurity landscape marked by escalating data breaches and regulatory demands, data leakage prevention (DLP) has emerged as one of several defense mechanisms. This study underscores unresolved foundational issues within DLP, revealing that it remains a significant challenge in large organizations. This highlights the necessity for a holistic approach to DLP to effectively address these persistent challenges. By developing a DLP Maturity Model, adapted from the renowned C2M2 framework, this research provides a comprehensive tool for assessing organizational DLP capabilities and pinpointing critical gaps. Applying the DLP Maturity Model within the financial sector as demonstrated through a banking scenario showcases its relevance and added value. This application illuminates the model's effectiveness in securing sensitive data and adhering to essential regulatory standards, highlighting its adaptability across various compliance landscapes. Implementing this DLP Maturity Model in a banking scenario showcases its applicability, highlighting its ability to formulate a strategy to secure sensitive data and comply with regulatory standards. This approach aligns with the concept of a continuous risk-based strategy, merging the holistic model to identify and address critical insider risks within organizations. The study addresses a specific gap in DLP research, notably the lack of a holistic framework for assessing and enhancing DLP strategies across organizations. It equips practitioners with a foundational tool to determine current DLP maturity and devise strategies for mitigating insider-driven data breach risks, thereby bolstering organizational cybersecurity resilience. [ABSTRACT FROM AUTHOR]

Prototyping technology is becoming vital in the business as a means of cutting costs and manufacturing time. At present, reverse engineering and rapid prototyping are important technologies that enhance prototype development. The traditional approaches require various intricate processes, such as selective heat sintering (SHS), digital-light-processing printer (DLP), remote distributed rapid prototyping model (RDRP), Stereo lithography (STL) models, and reconstructing computer-aided design (CAD) models from scanned point data and these approaches has limitations in terms of time-consuming and expert knowledge required for automation. This study aims to explore the significance of Industry 4.0 and its impact on rapid prototyping. The study also addresses rapid prototyping in computer network architecture; digital-light-processing printers (DLP) in rapid prototyping, and software-defined network (SDN) networks in the con-text of rapid prototyping. Along with this powder bed fusion (PBF) method and electron beam melting (EBM) are included in the manuscript. Based on our exploration, the study suggested vital recommendations for the advancement in rapid prototyping using Industry 4.0 [ABSTRACT FROM AUTHOR]

Zirconia‐toughened alumina (ZTA) composite ceramics show great potential for use in dental repair applications due to their unique properties. Complex‐shaped ZTA all‐porcelain crowns can be accurately fabricated using digital light processing (DLP) technology. However, effectively controlling both the anisotropy on mechanical property and surface quality of ZTA composites shaped by DLP remains a critical challenge that requires further research and innovation. In this work, we propose an efficient method to synchronously enhance the isotropy on mechanical performance and surface quality of DLP formed ZTA all‐porcelain crowns by controlling contents of yttria‐stabilized zirconia (YSZ) powders. When enhancing contents of YSZ from 5 to 20 wt%, multilayer microstructure with obvious interlayer gaps transformed into uniform microstructure with strong interlayer bonding, and the smaller alumina grain was observed on the stair‐stepping microstructure. Finally, the ZTA composites exhibited flexural and comprehensive strength as high as 640.3 and 6.9 MPa, and dimensional precision as low as 37.5 and 43.5 μm on top and side surface, together with simultaneously enhanced isotropy on mechanical property and surface quality, well satisfying the demands for all‐porcelain crowns fabricating. This study provides thorough understandings on isotropy regulating of DLP‐shaped ZTA all‐porcelain crowns with excellent mechanical performance and surface quality. [ABSTRACT FROM AUTHOR]

Purpose: Three-dimensional (3D) printing is popular for many applications including the production of photocatalysts. This paper aims to focus on developing of 3D-printed photocatalyst-nano composite lattice structure. Digital light processing (DLP) 3D printing of photocatalyst composites was performed using photosensitive resin mixed with 0.5% Wt. of TiO2 powder and varying amounts (0.025% Wt. to 0.2% Wt.) of graphene nanoplatelet powder. The photocatalytic efficiency of DLP 3D-printed photocatalyst TiO2 composite was investigated, and the effects of nano graphite powder incorporation on the photocatalytic activity, thermal and mechanical properties were investigated. Design/methodology/approach: Methods involve 3D computer-aided design modeling, printing parameters and comprehensive characterization techniques such as structural equation modeling, X-ray diffraction, thermogravimetric analysis, Fourier-transform infrared (FTIR) and mechanical testing. Findings: Results highlight successful dispersion and characteristics of TiO2 and graphene nanoplatelet (GNP) powders, intricate designs of 3D-printed lattice structures, and the influence of GNPs on thermal behavior and mechanical properties. Originality/value: The study suggests applicability in wastewater treatment and environmental remediation, showcasing the adaptability of 3 D printing in designing effective photocatalysts. Future research should focus on practical applications and the long-term durability of these 3D-printed composites. [ABSTRACT FROM AUTHOR]

Objective: This study investigates the correlation between patient body metrics and radiation dose in abdominopelvic CT scans, aiming to identify significant predictors of radiation exposure. Methods: Employing a cross-sectional analysis of patient data, including BMI, abdominal fat, waist, abdomen, and hip circumference, we analyzed their relationship with the following dose metrics: the CTDIvol, DLP, and SSDE. Results: Results from the analysis of various body measurements revealed that BMI, abdominal fat, and waist circumference are strongly correlated with increased radiation doses. Notably, the SSDE, as a more patient-centric dose metric, showed significant positive correlations, especially with waist circumference, suggesting its potential as a key predictor for optimizing radiation doses. Conclusions: The findings suggest that incorporating patient-specific body metrics into CT dosimetry could enhance personalized care and radiation safety. Conclusively, this study highlights the necessity for tailored imaging protocols based on individual body metrics to optimize radiation exposure, encouraging further research into predictive models and the integration of these metrics into clinical practice for improved patient management. [ABSTRACT FROM AUTHOR]

Non-metallic additive manufacturing technology has seen a substantial improvement in the precision of the parts it produces. Its capability to achieve complex geometries and very small dimensions makes it suitable for integration into strategic industrial sectors, such as aeronautics and medicine. Among additive manufacturing technologies, resin development processes demonstrate enhanced precision when compared to other methods, like filament printing. This study conducts a comparative analysis between digital light processing (DLP) and liquid crystal display (LCD) photopolymerization processes to assess the performance of the technologies and how process parameters affect the accuracy of the resulting parts. The research evaluates the impact of the discretization process used during the digital model export, determining the optimal mesh size and then analyzing the geometric deviations that occur by altering various operating parameters of the process. Statistical methods will be employed to identify the most significant parameters in the manufacturing process. Among other aspects, the precision of manufacturing technologies regarding the movement axis has also been evaluated. Regarding the minimum size of the features that can be fabricated, DLP technology has surpassed LCD technology, successfully producing features as small as 200 µm, compared to 500 µm for LCD technology. [ABSTRACT FROM AUTHOR]

Digital light processing (DLP) based three‐dimensional (3D) printing technology which uses photocurable resin has been a center of interest due to its printing accuracy and printing speed. In our research, we have synthesized and modified the bisphenol A‐based epoxy acrylate resin for the DLP 3D printer having a printing accuracy of 50 μm. As the viscosity plays an important role in printing accuracy, the resin was modified with mono‐functional, di‐functional, tri‐functional, and combination of di‐tri functional acrylate diluents as well as with photoinitiator to achieve the desired level of viscosity. The process parameters like curing time and intensity were optimized using the DLP 3D printer. The uncured and UV‐cured samples were characterized using FTIR‐ATR, 1HNMR, UV–VISIBLE, and TGA techniques. The analysis of the uncured and UV‐cured samples was carried out using viscosity, gel content, water absorption, and chemical resistance test. The mechanical properties of the UV‐cured samples were determined using hardness and tensile strength test. The 3D‐printed samples were observed under high‐resolution microscope to confirm the printing quality and resolution. The resulting outcome confirmed that the proper selection of diluents is an important parameter for achieving the good quality and resolution of samples printed using the DLP 3D printer technology. Highlights: Synthesis and modification of UV‐curable resinSelection of diluents for controlling the processablility of UV‐curable resinOptimization of process parameters for DLP based 3D printer3D printing of samples having good quality, resolution and feature size. [ABSTRACT FROM AUTHOR]

The general requirement of replacing petroleum-derived plastics with renewable resources is particularly challenging for new technologies such as the additive manufacturing of photocurable resins. In this work, the influence of mono- and bifunctional reactive diluents on the printability and performance of resins based on acrylated epoxidized soybean oil (AESO) was explored. Polyethylene glycol di(meth)acrylates of different molecular weights were selected as diluents based on the viscosity and mechanical properties of their binary mixtures with AESO. Ternary mixtures containing 60% AESO, polyethylene glycol diacrylate (PEGDA) and polyethyleneglycol dimethacrylate (PEG200DMA) further improved the mechanical properties, water resistance and printability of the resin. Specifically, the terpolymer AESO/PEG575/PEG200DMA 60/20/20 (wt.%) improved the modulus (16% increase), tensile strength (63% increase) and %deformation at the break (21% increase), with respect to pure AESO. The enhancement of the printability provided by the reactive diluents was proven by Jacobs working curves and the improved accuracy of printed patterns. The proposed formulation, with a biorenewable carbon content of 67%, can be used as the matrix of innovative resins with unrestricted applicability in the electronics and biomedical fields. However, much effort must be done to increase the array of bio-based raw materials. [ABSTRACT FROM AUTHOR]

In an evolving cybersecurity landscape marked by escalating data breaches and regulatory demands, data leakage prevention (DLP) has emerged as one of several defense mechanisms. This study underscores unresolved foundational issues within DLP, revealing that it remains a significant challenge in large organizations. This highlights the necessity for a holistic approach to DLP to effectively address these persistent challenges. By developing a DLP Maturity Model, adapted from the renowned C2M2 framework, this research provides a comprehensive tool for assessing organizational DLP capabilities and pinpointing critical gaps. Applying the DLP Maturity Model within the financial sector as demonstrated through a banking scenario showcases its relevance and added value. This application illuminates the model’s effectiveness in securing sensitive data and adhering to essential regulatory standards, highlighting its adaptability across various compliance landscapes. Implementing this DLP Maturity Model in a banking scenario showcases its applicability, highlighting its ability to formulate a strategy to secure sensitive data and comply with regulatory standards. This approach aligns with the concept of a continuous risk-based strategy, merging the holistic model to identify and address critical insider risks within organizations. The study addresses a specific gap in DLP research, notably the lack of a holistic framework for assessing and enhancing DLP strategies across organizations. It equips practitioners with a foundational tool to determine current DLP maturity and devise strategies for mitigating insider-driven data breach risks, thereby bolstering organizational cybersecurity resilience.

One therapeutical alternative in the treatment of functional disorders is the use of printed oral splints. The mechanical properties of these materials are highly essential to their clinical effectiveness, and their performance may vary depending on factors such as cleaning, post-polymerization, or their orientation during construction. The objective of this in vitro investigation is to evaluate the effectiveness of the selected materials in terms of their biaxial flexural strength in relation to the criteria listed above. Splint materials were used in the printing of 720 discs. The printing process was carried out in different orientations in relation to the building platform. Either an automatic or manual cleaning process was performed on the samples. For post-polymerization, either an LED or Xenon light was utilized. A piston-on-three-ball test was used to measure the biaxial flexural strength (BFS) of the materials after they were stored in water for either 24 h or 60 days. The homogeneity of the data was controlled by employing the Levene method, and the differences between the groups were analyzed using the ANOVA and Bonferroni methods. After being stored for twenty-four hours, the mean BFS ranged anywhere from 79 MPa to 157 MPa. Following a period of sixty hours, the BFS exhibited a substantial drop and revealed values that ranged from 72 to 127 MPa. There was no significant difference that could be identified between the materials or between the various cleaning processes. The results of post-polymerization showed that the LED light produced higher means than the Xenon light did. In terms of position, the mean values varied greatly, with 0°'s mean value being 101 MPa, 45°'s mean value being 102 MPa, and 90°'s mean value being 115 MPa. The use of a build orientation of 90° and post-polymerization with LED light resulted in significantly increased biaxial flexural strength. According to this study, this design should be implemented in order to ensure that splint materials have the highest possible strength. [ABSTRACT FROM AUTHOR]

A low‐viscosity bio‐based carbamate acrylate was synthesized by the reaction of pentamethylene diisocyanate derived from pentanediamine with a low molecular weight acrylate hydroxyl ester. The carbamate acrylate was used in the 3D printing of ceramics, and a correlation between the solid content and viscosity of the ceramic slurry was observed. The ceramic slurry exhibits good stability and low shrinkage. The results indicate that the viscosity of the ceramic slurry was 2.11 Pa s with a solid content of 80 wt%, which makes it suitable for digital light processing printing. In addition, a new type of photoinitiator called (2,4,6‐trimethylbenzoyl)bis(p‐tolyl)phosphine oxide (TMO) has been applied, demonstrating excellent potential in ceramic slurry. According to its thermogravimetric curve, a debinding and sintering process was designed, and ultimately an Al2O3 device with a density of 94.49% was prepared. [ABSTRACT FROM AUTHOR]

Purpose: The paper shows a preliminary study of the basic strength parameters of printed parts made of biocompatible polymers with ceramic layers applied to increase the strength of the tool cutting surface. Methods: The specimens were made from different materials and using different 3D printing technologies and the working surfaces that will eventually form the cutting element of the tool were coated with Al2O3. Gloss tests were conducted, properties of the coating, a scratch test of the coated surface, also evaluated surface topography. Results: Based on the conducted research, it was found that polymeric materials are characterized by sufficient strength and can be used for disposable tools, however, the use of thin layers of Al2O3 significantly increases the surface strength parameters, which may have a significant impact on the reliability and durability of the tools. The polymer surface covered with an Al2O3 layer is characterised by increased scratch resistance ranging from 24% to 75% depending on the core material and printing technology. The gloss of the surfaces is disproportionately low compared to currently used metal tools, which indicates that they can be used in endoscopic procedures. Conclusions: Based on the conducted research, it was found that the use of thin layers of Al2O3 covering polymer 3D prints is an excellent way to increase strength parameters such as scratch resistance, tribological parameters and light reflections arising on the surface as a result of endoscopic lighting are disproportionately small compared to metallic biomaterials. This gives great hope for using polymer 3D prints for personalised neurosurgical tools. [ABSTRACT FROM AUTHOR]

Computed tomography urography (CTU) comprehensively evaluates the urinary tract. However, the procedure is associated with a high radiation dose due to multiple scan series and therefore requires optimisation. The study performed CTU protocol optimisation based on a reduction in tube voltage (kV) using quality assurance (QA) phantom and clinical images and evaluated image quality and radiation dose. The study was prospectively conducted on patients referred for CTU. The patients were grouped into A and B and were scanned with the standard protocol, a protocol used for the routine CTU at the CT centre before optimisation, and optimised protocol, a protocol with reduced kV respectively. The protocols were first tried on a quality assurance (QA) phantom before being applied to patients, and image quality was assessed based on signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). In addition, the clinical images were assessed based on the visibility of the anatomical criteria for CT images by five observers with >5 years of experience. The data were analysed using both visual grading characteristic (VGC) curves and statistical package for social sciences (SPSS) version 22.0. The dose was significantly lower in the optimised protocol with a 10 % reduction in both volume computed tomography dose index and (CTDIvol) and dose length product (DLP) for the phantom images, and a 26 % reduction in CTDIvol and 28 % in DLP for the clinical images. However, there was no significant difference in image quality noted between the standard and optimised protocols based on the quantitative and qualitative image quality evaluation using both the QA phantom and clinical images. The findings revealed a significant dose reduction in the optimised protocol. Further, image quality in standard and optimised protocols did not differ significantly based on quantitative and qualitative methods. kV optimisation in contrast-enhanced procedures provides dose reduction and should be encouraged in the medical imaging departments. [ABSTRACT FROM AUTHOR]

PURPOSEWhen a suspected hepatic alveolar echinococcosis (AE) lesion is detected on a contrast enhanced computed tomography (CT) scan, an additional triphasic or non-enhanced CT scan is required to determine the presence of calcification and enhancement. As a result, imaging costs and exposure to ionizing radiation will increase. We can create a non-enhanced series from routine contrast-enhanced images using dual-energy CT (DECT) and virtual non-enhanced (VNE) images. This study’s objective is to assess virtual non-enhanced DECT reconstruction as a potential diagnostic tool for hepatic AE.METHODSTriphasic CT scans and a routine dual energy venous phase were acquired using a third-generation DECT system. A commercially available software package was used to generate VNE images. Individual evaluations were conducted by two radiologists.RESULTSThe study population consisted of 100 patients (30 AE, 70 other solid liver masses). All AE cases were diagnosed [no false positives/negatives, 95% confidence interval (CI) sensitivity: 91.3%–100%; 95% CI specificity: 95.3%–100%]. Interrater agreement was k: 0.79. In total, 33 (33.00%) of the patients had AE, which was detected using both true non-enhanced (TNE) and VNE images. The mean dose-length product of a standard triphasic CT was significantly higher than biphasic dual-energy VNE images.CONCLUSIONIn terms of diagnostic confidence, VNE images are comparable with actual non-enhanced imaging when evaluating hepatic AE. Further, VNE images could replace TNE images with a substantial radiation dose reduction. Advances in knowledge: hepatic cystic echinococcosis and AE are serious and severe diseases with high fatality rates and a poor prognosis if managed incorrectly, especially AE. Moreover, VNE images produce equal diagnostic confidence to TNE images for assessing liver AE, with a significant reduction in radiation dose.

Modern technologies like quantum and cloud computing have reshaped computing, offering immense power and scalability. While beneficial, they also challenge the security of traditional cryptographic systems. Quantum computing threatens RSA and ECC with algorithms like Shor’s algorithm, which can accelerate computations exponentially. This risks exposing these systems to attacks, necessitating quantum-resistant cryptography. Cloud computing poses data security concerns, requiring robust cryptographic mechanisms and access controls. Lattice-based cryptography, leveraging problems like the Short Integer Solution (SIS), emerges as a solution. This paper presents a novel quantum-resistant public key encryption scheme based on ElGamal and SIS, ensuring security against quantum and classical threats in modern cryptographic environments.

Glypicans are closely associated with organ development and tumorigenesis in animals. Dally-like (Dlp), a membrane-bound glypican, plays pivotal roles in various biological processes in Drosophila. In this study, we observed that an excess of Dlp led to the malformation of legs, particularly affecting the distal part. Accordingly, the leg disc was shrunken and frequently exhibited aberrant morphology. In addition, elevated Dlp levels induced ectopic cell death with no apparent cell proliferation changes. Furthermore, Dlp overexpression in the posterior compartment significantly altered Wingless (Wg) distribution. We observed a marked expansion of Wg distribution within the posterior compartment, accompanied by a corresponding decrease in the anterior compartment. It appears that excess Dlp guides Wg to diffuse to cells with higher Dlp levels. In addition, the distal-less (dll) gene, which is crucial for leg patterning, was up-regulated significantly. Notably, dachshund (dac) and homothorax (hth) expression, also essential for leg patterning and development, only appeared to be negligibly affected. Based on these findings, we speculate that excess Dlp may contribute to malformations of the distal leg region of Drosophila, possibly through its influence on Wg distribution, dll expression and induced cell death. Our research advances the understanding of Dlp function in Drosophila leg development.

Fabrication of glass with complex geocd the low resolution of particle‐based or fused glass technologies. Herein, a high‐resolution 3D printing of transparent nanoporous glass is presented, by the combination of transparent photo‐curable sol–gel printing compositions and digital light processing (DLP) technology. Multi‐component glass, including binary (Al2O3‐SiO2), ternary (ZnO‐Al2O3‐SiO2, TiO2‐Al2O3‐SiO2), and quaternary oxide (CaO‐P2O5‐Al2O3‐SiO2) nanoporous glass objects with complex shapes, high spatial resolutions, and multi‐oxide chemical compositions are fabricated, by DLP printing and subsequent sintering process. The uniform nanopores of Al2O3‐SiO2‐based nanoporous glasses with the diameter (≈6.04 nm), which is much smaller than the visible light wavelength, result in high transmittance (>95%) at the visible range. The high surface area of printed glass objectives allows post‐functionalization via the adsorption of functional guest molecules. The photoluminescence and hydrophobic modification of 3D printed glass objectives are successfully demonstrated. This work extends the scope of 3D printing to transparent nanoporous glasses with complex geometry and facile functionalization, making them available for a wide range of applications. [ABSTRACT FROM AUTHOR]

The widespread use of epoxy resin (ER) in industry, owing to its excellent properties, aligns with the global shift toward greener resources and energy-efficient solutions, where utilizing metal oxides in 3D printed polymer parts can offer extended functionalities across various industries. ZnO concentrations in polyurethane acrylate composites impacted adhesion and thickness of DLP samples, with 1 wt.% achieving a thickness of 3.99 ± 0.16 mm, closest to the target thickness of 4 mm, while 0.5 wt.% ZnO samples exhibited the lowest deviation in average thickness (±0.03 mm). Tensile stress in digital light processed (DLP) composites with ZnO remained consistent, ranging from 23.29 MPa (1 wt.%) to 25.93 MPa (0.5 wt.%), with an increase in ZnO concentration causing a reduction in tensile stress to 24.04 MPa and a decrease in the elastic modulus to 2001 MPa at 2 wt.% ZnO. The produced DLP samples, with their good corrosion resistance in alkaline environments, are well-suited for applications as protective coatings on tank walls. Customized DLP techniques can enable their effective use as structural or functional elements, such as in Portland cement concrete walls, floors and ceilings for enhanced durability and performance. [ABSTRACT FROM AUTHOR]

Adding wood fiber to the 3D printing material can make the 3D-printed product have the characteristics of natural dyeing and material. Because wood fiber is mostly waste and cheap, it can reduce material cost. For environmental sustainability, it is a very promising filling material. Currently, there are 3D printing consumables using wood fiber on the market, most of which are made by drawing wires with polylactic acid (PLA). Due to the low accuracy and yield of frequency-division multiplexing (FDM) printing using filaments, it cannot be extended to mass production industrial use, and natural pellets cause the problem of nozzle clogging. In contrast, if fiber is mixed with polyurethane acrylate (PUA), it can be printed by DLP and cured through the photocuring reaction. This method has no clogging problem and has high printing accuracy, enabling industrialized mass production that requires high yield and accuracy. Therefore, in this study, Taiwan incense-cedar (high economic and ecological value tree species) was applied to commercial PUA materials for DLP 3D printing. Mix wood fiber with different ratios and commercial PUA, conduct printing and performance tests, and then compare the mechanical properties and finished product effects with commercial PLA printed products that add wood fiber. [ABSTRACT FROM AUTHOR]

Microfluidic chips have shown their potential for applications in fields such as chemistry and biology, and 3D printing is increasingly utilized as the fabrication method for microfluidic chips. To address key issues such as the long printing time for conventional 3D printing of a single chip and the demand for rapid response in individualized microfluidic chip customization, we have optimized the use of DLP (digital light processing) technology, which offers faster printing speeds due to its surface exposure method. In this study, we specifically focused on developing a fast-manufacturing process for directly printing microfluidic chips, addressing the high cost of traditional microfabrication processes and the lengthy production times associated with other 3D printing methods for microfluidic chips. Based on the designed three-dimensional chip model, we utilized a DLP-based printer to directly print two-dimensional and three-dimensional microfluidic chips with photosensitive resin. To overcome the challenge of clogging in printing microchannels, we proposed a printing method that combined an open-channel design with transparent adhesive tape sealing. This method enables the rapid printing of microfluidic chips with complex and intricate microstructures. This research provides a crucial foundation for the development of microfluidic chips in biomedical research. [ABSTRACT FROM AUTHOR]

Additive manufacturing technologies have developed rapidly in recent decades, pushing the limits of known manufacturing processes. The need to study the properties of the different materials used for these processes comprehensively and in detail has become a primary goal in order to get the best out of the manufacturing itself. The widely used thermoplastic polymer material acrylonitrile butadiene styrene (ABS) was selected in the form of both filaments and ABS-like resins to investigate and compare the mechanical properties through a series of different tests. ABS-like resin material is commercially available, but it is not a sufficiently mechanically studied form of the material, which leads to the rather limited literature. Considering that ABS resin is a declared material that behaves like the ABS filament but in a different form, the objective of this study was to compare these two commercially available materials printed with three different 3D printers, namely Fused Deposition Modelling (FDM), Stereolithography (SLA) and Digital Light Processing (DLP). A total of 45 test specimens with geometries and test protocols conforming to the relevant standards were subjected to a series of tensile, three-point bending and compression tests to determine their mechanical properties. Characterization also included evaluation of morphology with 2D and 3D microscopy, dimensional accuracy of 3D scans, and Shore A hardness of each material and 3D printing process. Tensile testing results have shown that FDM toughness is 40% of the value for DLP. FDM elongation at break is 37% of DLP, while ultimate tensile stress for SLA is 27% higher than FDM value. Elastic modulus for FDM and SLA coincide. Flexure testing results indicate that value of DLP flexural modulus is 54% of the FDM value. SLA strain value is 59% of FDM, and DLP ultimate flexure stress is 77% of the value for FDM. Compression test results imply that FDM specimens absorb at least twice as much energy as vat polymerized specimens. Strain at break for SLA is 72% and strain at ultimate stress is 60% of FDM values. FDM yield stress is 32% higher than DLP value. SLA ultimate compressive stress is half of FDM, while value for DLP compressive modulus is 69% of the FDM value. The results obtained are beneficial and give a more comprehensive picture of the behavior of the ABS polymers used in different forms and different AM processes. [ABSTRACT FROM AUTHOR]