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279 results on '"DI GIACOMO, Silvia"'

1. Erice Manifesto 2022: On the Surveillance of Potential Harms Caused by Food Supplements in Europe

Author

Menniti-Ippolito, Francesca, Aiello, Eugenio, Arzenton, Elena, Assisi, Alessandro, Blaznik, Urška, Castenmiller, Jacqueline J. M., Crevani, Marta, de Clock, Dominique, Di Giacomo, Silvia, Emendi, Silvia, Gonella, Laura Augusta, Ippoliti, Ilaria, Lindquist, Marie, Magro, Lara, Mazzanti, Gabriela, Mores, Nadia, Moretti, Ugo, Moro, Paola Angela, Novakovic, Budimka, Raschi, Emanuel, Siksna, Inese, Valetto, Maria Rosa, Vitalone, Annabella, and Vo Van Regnault, Gwenn

Published
2023
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3. Hydrolysates from cauliflower and artichoke industrial wastes as biostimulants on seed germination and seedling growth: a chemical and biological characterization.

Author

Salvo, Andrea, Masciulli, Fabrizio, Ambroselli, Donatella, Romano, Enrico, Ingallina, Cinzia, Spano, Mattia, Di Matteo, Giacomo, Giusti, Anna Maria, Di Sotto, Antonella, Percaccio, Ester, Di Giacomo, Silvia, Vinci, Giuliana, Prencipe, Sabrina Antonia, Acciaro, Erica, Sobolev, Anatoly P., Costantini, Lara, Merendino, Nicolò, Giulianelli, Roberto, Campiglia, Enio, and Mannina, Luisa

Subjects
INDUCTIVELY coupled plasma mass spectrometry, ARTICHOKES, COLE crops, INDUSTRIAL wastes, AGRICULTURAL wastes, DURUM wheat
Abstract

Background: Cauliflower (Brassica oleracea L.) and globe artichoke (Cynara scolymus L.) are vegetables with a high waste index mainly related to stems and leaves. In this study, enzymatic hydrolysates obtained from these wastes were proposed to be used as plant biostimulants. Life cycle assessment methodology was also applied to evaluate environmental performances related to cauliflower and artichoke byproducts. Results: Hydrolysates (HYs) were chemically and biologically characterized. Amino acids, organic acids, amines, polyols, mineral elements, phenols, tannins, flavonoids and sulfur compounds were identified and quantified by means of NMR, inductively coupled plasma mass spectrometry and UV–visible analyses. Cauliflower leaf and flower HYs showed the highest concentration of free amino acids, whereas stems showed the highest concentration of Ca. Regarding artichoke, asparagine, glutamine and aspartic acid were exclusively detected in stems, whereas artichoke leaves showed the highest Mg and Mn levels together with the highest antioxidant activity. The HYs diluted in water were tested as biostimulants. The impacts of five concentrations of HYs (0.00, 0.28, 0.84, 2.52 and 7.56 g L−1) on seed germination and early seedling growth of crimson clover, alfalfa, durum wheat and corn were investigated. Conclusions: The application of artichoke biostimulant (0.28 g L−1) positively influenced the coefficient of velocity of germination in alfalfa, crimson clover and durum wheat, whereas cauliflower biostimulant significantly improved corn germination speed. © 2024 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. [ABSTRACT FROM AUTHOR]

Published
2025
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4. Different patterns of neurogenic quadrilateral space syndrome: a case series of undefined posterior shoulder pain.

Author

Porcellini, Giuseppe, Brigo, Alberto, Novi, Michele, De Santis, Elisa, Di Giacomo, Silvia, Giorgini, Andrea, Micheloni, Gian Mario, Bonfatti, Rocco, Donà, Alessandro, and Tarallo, Luigi

Subjects
MAGNETIC resonance imaging, DELAYED diagnosis, MEDICAL sciences, SHOULDER pain, SURGICAL decompression
Abstract

Background: Quadrilateral space syndrome is a painful disorder of the shoulder caused by static or dynamic entrapment of the axillary nerve and the posterior humeral circumflex artery. It was first described in 1983; however, it is an uncommon syndrome that initially presents with nonspecific shoulder pain or selective deltoid atrophy, and diagnosis is often delayed owing to its rarity. Young athletes of overhead sports are more commonly affected by this syndrome. Symptoms of quadrilateral space syndrome include silent deltoid atrophy, persistent posterior shoulder pain, paresthesias, and tenderness over the quadrilateral space. Vascular symptoms may involve thrombosis and embolisms of the upper limb. Instrumental tests and imaging are not always conclusive, leading to frequent misdiagnosis of the syndrome. Patients and methods: The aim of this study is to present a case series of four patients diagnosed with neurogenic quadrilateral space syndrome, describe different clinical presentations, and suggest tips for diagnosing this syndrome. All patients underwent a detailed medical history collection, were interviewed about the sports and hobbies they engaged in, and received a comprehensive clinical examination of the neck and shoulder. Patients also underwent diagnostic exams such as magnetic resonance imaging (MRI) and electromyography. An ultrasound-guided injection of local anesthetic was performed into the quadrilateral space. Results: All patients affected by neurogenic quadrilateral space syndrome underwent conservative treatment, which included a rehabilitation program. Only one out of four patients experienced complete resolution of symptoms and did not require surgical decompression. Conclusions: To properly treat this rare syndrome, we propose classifying it as either "dynamic" or "static," on the basis of the clinical history, MRI findings, and physical examination. The study includes a rehabilitation program that was effective for one patient, demonstrating that surgical decompression may be avoidable if the cases are promptly diagnosed and classified. Level of evidence IV according to "The Oxford 2011 Levels of Evidence" [ABSTRACT FROM AUTHOR]

Published
2025
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5. Modulatory Effect of Cucurbitacin D from Elaeocarpus hainanensis on ZNF217 Oncogene Expression in NPM-Mutated Acute Myeloid Leukemia.

Author

Adorisio, Sabrina, Fierabracci, Alessandra, Cham, Ba Thi, Hoang, Vu Dinh, Thuy Linh, Nguyen Thi, Nhung, Le Thi Hong, Martelli, Maria Paola, Ayroldi, Emira, Ronchetti, Simona, Rosati, Lucrezia, Di Giacomo, Silvia, Thuy, Trinh Thi, and Delfino, Domenico Vittorio

Subjects
ACUTE myeloid leukemia, HEMATOLOGIC malignancies, MYELOID cells, CELL cycle, CANCER cells, ZINC-finger proteins
Abstract

Background/Objectives: The expression of oncogene zinc-finger protein 217 (ZNF217) has been reported to play a central role in cancer development, resistance, and recurrence. Therefore, targeting ZNF217 has been proposed as a possible strategy to fight cancer, and there has been much research on compounds that can target ZNF217. The present work investigates the chemo-preventive properties of cucurbitacin D, a compound with a broad range of anticancer effects, in hematological cancer cells, specifically with regard to its ability to modulate ZNF217 expression. Methods: Different cucurbitacins were isolated from the Vietnamese plant Elaeocarpus hainanensis. The purified compounds were tested on nucleophosmin-mutated acute myeloid leukemia and other hematological cancer cell lines to assess their effects on the cell cycle, cell viability and apoptosis, and the expression of ZNF217. Results: Cucurbitacin D resulted in a reduction in the number of acute myeloid leukemia cells by inducing an increase in apoptosis and blocking cell cycle progression. It also led to a significant decrease in ZNF217 expression in the nucleophosmin-mutated acute myeloid leukemia cell line but not in the other hematologic cancer cell lines. The reduction in ZNF217 expression contributed significantly to the blocking of cell cycle progression but did not affect apoptosis. Conclusions: The obtained results suggest that cucurbitacin D is a promising molecule for targeting mutated nucleophosmin or its pathway in acute myeloid leukemia cells, although further studies are needed for in-depth investigations into its specific mechanisms. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Evaluation of the Antifungal and Antiproliferative Properties of the Lichen Roccella tinctoria DC. Extracts and Main Components

Author

Frezza, Claudio, primary, Fraioli, Dalia Rosa, additional, Conti, Francesca, additional, Nicolosi, Roberta Maria, additional, Scipione, Luigi, additional, Serafini, Ilaria, additional, Petrucci, Rita, additional, Di Matteo, Paola, additional, Rocco, Daniele, additional, Di Giacomo, Silvia, additional, Di Sotto, Antonella, additional, Bonincontro, Graziana, additional, Simonetti, Giovanna, additional, Garzoli, Stefania, additional, De Vita, Daniela, additional, and Foddai, Sebastiano, additional

Published
2024
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10. Management of Epicondylitis and Epitrochleitis

Author

Di Giacomo, Silvia, Porcellini, Giuseppe, Tartarone, Antonio, Paladini, Paolo, Pellegrini, Andrea, Ricci, Annamaria, d’Agostino, Maria Cristina, Turoni, Riccardo, Porcellini, Giuseppe, editor, Rotini, Roberto, editor, Stignani Kantar, Susanna, editor, and Di Giacomo, Silvia, editor

Published
2018
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11. Rehabilitation After Elbow Prosthesis

Author

Fusaro, Isabella, Orsini, Stefania, Minelli, Giulia, Kantar, Susanna Stignani, Di Giacomo, Silvia, dos Santos Flöter, Michelle, Ritali, Alice, Benedetti, Maria Grazia, Porcellini, Giuseppe, editor, Rotini, Roberto, editor, Stignani Kantar, Susanna, editor, and Di Giacomo, Silvia, editor

Published
2018
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13. First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT6 Agents with a Beneficial Neuroprotective Profile against Alzheimer’s Disease

Author

Pyka, Patryk, primary, Haberek, Wawrzyniec, additional, Więcek, Małgorzata, additional, Szymanska, Ewa, additional, Ali, Wesam, additional, Cios, Agnieszka, additional, Jastrzębska-Więsek, Magdalena, additional, Satała, Grzegorz, additional, Podlewska, Sabina, additional, Di Giacomo, Silvia, additional, Di Sotto, Antonella, additional, Garbo, Sabrina, additional, Karcz, Tadeusz, additional, Lambona, Chiara, additional, Marocco, Francesco, additional, Latacz, Gniewomir, additional, Sudoł-Tałaj, Sylwia, additional, Mordyl, Barbara, additional, Głuch-Lutwin, Monika, additional, Siwek, Agata, additional, Czarnota-Łydka, Kinga, additional, Gogola, Dawid, additional, Olejarz-Maciej, Agnieszka, additional, Wilczyńska-Zawal, Natalia, additional, Honkisz-Orzechowska, Ewelina, additional, Starek, Małgorzata, additional, Dąbrowska, Monika, additional, Kucwaj-Brysz, Katarzyna, additional, Fioravanti, Rossella, additional, Nasim, Muhammad Jawad, additional, Hittinger, Marius, additional, Partyka, Anna, additional, Wesołowska, Anna, additional, Battistelli, Cecilia, additional, Zwergel, Clemens, additional, and Handzlik, Jadwiga, additional

Published
2024
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26. Liver and gastrointestinal cancers

Author

Marin, Jose J.G., primary, Macias, Rocio I.R., additional, Herraez, Elisa, additional, Lozano, Elisa, additional, Romero, Marta R., additional, Di Giacomo, Silvia, additional, Efferth, Thomas, additional, and Briz, Oscar, additional

Published
2020
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27. Contributors

Author

Alam, Camille, primary, An, Guohua, additional, Behar-Cohen, Francine, additional, Bendayan, Reina, additional, Briz, Oscar, additional, Cassoux, Nathalie, additional, Cisternino, Salvatore, additional, Declèves, Xavier, additional, Di Giacomo, Silvia, additional, Efferth, Thomas, additional, Elmquist, William F., additional, Eyal, Sara, additional, Gampa, Gautham, additional, Griffith, Jessica, additional, Hamblin, Michael R., additional, Herraez, Elisa, additional, Kim, Minjee, additional, Kumarasamy, Murali, additional, Lazarowski, Alberto, additional, Leslie, Elaine M., additional, Lozano, Elisa, additional, Macias, Rocio I.R., additional, Marin, Jose J.G., additional, Matet, Alexandre, additional, Mohammad, Afroz, additional, Morris, Marilyn E., additional, Romero, Marta R., additional, Sosnik, Alejandro, additional, Talele, Surabhi, additional, Turner, Adrian P., additional, Whitlock, Brayden D., additional, Wong, Ho-Lun, additional, and Xue, Hui-Yi, additional

Published
2020
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30. First-in-Class Selenium-Containing Potent Serotonin Receptor 5‑HT6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease.

Author

Pyka, Patryk, Haberek, Wawrzyniec, Więcek, Małgorzata, Szymanska, Ewa, Ali, Wesam, Cios, Agnieszka, Jastrzębska-Więsek, Magdalena, Satała, Grzegorz, Podlewska, Sabina, Di Giacomo, Silvia, Di Sotto, Antonella, Garbo, Sabrina, Karcz, Tadeusz, Lambona, Chiara, Marocco, Francesco, Latacz, Gniewomir, Sudoł-Tałaj, Sylwia, Mordyl, Barbara, Głuch-Lutwin, Monika, and Siwek, Agata

Published
2024
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32. Selenium-Containing Agents Acting on Cancer—A New Hope?

Author

Garbo, Sabrina, primary, Di Giacomo, Silvia, additional, Łażewska, Dorota, additional, Honkisz-Orzechowska, Ewelina, additional, Di Sotto, Antonella, additional, Fioravanti, Rossella, additional, Zwergel, Clemens, additional, and Battistelli, Cecilia, additional

Published
2022
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37. Rehabilitation After Elbow Prosthesis

Author

Fusaro, Isabella, primary, Orsini, Stefania, additional, Minelli, Giulia, additional, Kantar, Susanna Stignani, additional, Di Giacomo, Silvia, additional, dos Santos Flöter, Michelle, additional, Ritali, Alice, additional, and Benedetti, Maria Grazia, additional

Published
2017
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38. β-Caryophyllene Counteracts Chemoresistance Induced by Cigarette Smoke in Triple-Negative Breast Cancer MDA-MB-468 Cells

Author

Di Sotto, Antonella, primary, Gullì, Marco, additional, Minacori, Marco, additional, Mancinelli, Romina, additional, Garzoli, Stefania, additional, Percaccio, Ester, additional, Incocciati, Alessio, additional, Romaniello, Donatella, additional, Mazzanti, Gabriela, additional, Eufemi, Margherita, additional, and Di Giacomo, Silvia, additional

Published
2022
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44. Expression of Chemoresistance-Associated ABC Proteins in Hepatobiliary, Pancreatic and Gastrointestinal Cancers

Author

Marin, Jose, primary, Monte, Maria, additional, Macias, Rocio, additional, Romero, Marta, additional, Herraez, Elisa, additional, Asensio, Maitane, additional, Ortiz-Rivero, Sara, additional, Cives-Losada, Candela, additional, Di Giacomo, Silvia, additional, Gonzalez-Gallego, Javier, additional, Mauriz, Jose, additional, Efferth, Thomas, additional, and Briz, Oscar, additional

Published
2022
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