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Objective: Evaluation of the biomarkers and their relations with sleep in attention deficit hyperactivity disorder (ADHD) is important for understanding the impairments in cognitive functioning. In this study, we aimed to investigate the brain‐derived neurotrophic factor (BDNF) and sialic acid (Sia) levels, and their possible relations with chronotypes in ADHD. Methods: The study included 100 drug‐naive children with ADHD and 74 healthy children as controls. Conners' Parent Rating Scale‐Revised (CPRS‐R) scores were used for the severity assessment. Morningness Eveningness Questionnaire (MEQ) was used to determine the chronotypes of participants. ELISA kits were used for the assessment of BDNF and Sia plasma levels. Results: Levels of BDNF and Sia were found to be statistically significantly higher in the ADHD group compared to healthy children (p < 0.001, p < 0.001, respectively). BDNF and Sia levels were found to be higher in the ADHD group with eveningness chronotype (p = 0.045, p = 0.038). The binary logistic regression model was statistically significant (p = 0.033), higher BDNF and Sia levels were assessed as predictive factors for the diagnosis of ADHD. Also, eveningness chronotype was found as a predictive factor of BDNF and Sia levels in ADHD. Conclusion: The results indicate that BDNF and Sia levels, which are related to cognitive functions and sleep, increase with the age of ADHD. Eveningness chronotype, connected with the severity of ADHD, is related to BDNF and Sia levels. There is a need for further studies to confirm these results. [ABSTRACT FROM AUTHOR]

Non-suicidal self-injury (NSSI) continues to be an important problem in adolescents, and it was aimed to investigate the relationship between suicide probability, cyberbullying, impulsivity, and aggression with NSSI history in the adolescent clinical population on the basis of gender. 267 adolescents with a history of NSSI and 210 without were included. They filled the Inventory of Statements About Self-Injury (ISAS), Cyberbullying and Online Aggression Screening Scale (COASS), Buss-Perry Aggression Questionnaire (BPAQ), Suicide Probability Scale (SPS), Barratt Impulsiveness Scale-11-Short Form (BIS-11-SF). Four subscales and total scores of SPS, BPAQ, BIS-11-SF total scores were found to be significantly higher in males with a history of NSSI. BPAQ, BIS-11-SF motor, and attention impulsiveness, BIS-11-SF total scores, four subscales, and total scores of SPS were found to be significantly higher in females with a history of NSSI. Lower BIS-11-SF non-planning impulsivity, higher SPS/suicide ideation and hostility scores, and lower father's education level were found to be the best predictive factors for ISAS total scores in males. In females, experience cyberbullying, lower age, higher SPS/suicide ideation and total scores were the best predictors. Knowing the factors associated with NSSI and the differences between genders will be effective in both preventing NSSI and shaping treatment modalities. [ABSTRACT FROM AUTHOR]

Objective: Neurodevelopmental disorders (NDDs) are the most common psychiatric disorders in childhood, and there are many factors in their etiology. In recent years, many biomarkers have been studied to elucidate the etiology of these disorders. In this study, it was aimed to investigate the levels of nerve growth factor (NGF) and angiotensin converting enzyme 2 (ACE2) in attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and intellectual disability (ID). Methods: The study included 74 children with NDDs (the number of patients in ADHD, ASD and ID groups were 24, 25 and 25 respectively) and 30 healthy controls (HCs). Serum NGF and ACE2 levels were studied with ELISA kits, also complete blood count (CBC), levels of fasting glucose and serum lipids were assessed. Results: ACE2 levels were found to be lower in NDD group than HCs in girls. In boys with ASD, triglyceride levels were significantly higher than other groups. Also a positive correlation was found between ACE2 and NGF levels when all sample assessed together. Conclusions: This study is a premise for investigating ACE2 and NGF in NDDs. The role of these markers in ADHD, ASD, ID and other NDDs and their associations with gender should be assessed by studies in which both larger sample groups and more disorders. [ABSTRACT FROM AUTHOR]

Copyright of Turkish Journal of Child & Adolescent Mental Health / Çocuk ve Gençlik Ruh Sagligi Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of KADEM Journal of Women's Studies is the property of Women & Justice Association / Kadin & Demokrasi Dernegi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The aim of this study is to evalute the effects of methylphenidate and atomoxetine treatments on electroencephalography (EEG) signals in volunteer children diagnosed with Attention Deficit and Hyperactivity Disorder(ADHD).

Copyright of Nigde Omer Halisdemir University Journal of Engineering Sciences / Niğde Ömer Halisdemir Üniversitesi Mühendislik Bilimleri Dergisi is the property of Nigde Omer Halisdemir Universitesi (NOHU), Muhendislik Fakultesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: Cognitive disengagement syndrome, formerly known as sluggish cognitive tempo, is defined as mental fogginess, daydreaming, and sluggishness. This study aimed to determine the prevalence and sociodemographic characteristics of children with cognitive disengagement syndrome and to examine the relationship between cognitive disengagement syndrome and psychiatric disorders. Methods: About 268 randomly chosen Turkish primary school children aged 7-11 years from 4 different cities were included in this study. Both teachers and parents completed the cognitive disengagement syndrome scanning scale of the Child Behavior Checklist and the Barkley Child Attention Survey. Psychiatric diagnoses in children were assessed using a semi-structured clinical interview. Four separate cognitive disengagement syndrome measurements were performed, matching informants with scales. Results: The prevalence of cognitive disengagement syndrome was estimated with a range of 4.9%-10.9%, depending on the way of measurement. Logistic regression analyses revealed that paternal psychopathology (odds ratio = 6.7) and low maternal education (odds ratio = 3.1) increased while advanced maternal age (odds ratio = 0.7) decreased the risk of cognitive disengagement syndrome. Although cognitive disengagement syndrome was found to be more prevalent in children with chronic diseases, this association no longer remained in the full logistic regression model. Attention deficit/hyperactivity disorder was the most observed disorder and accompanied 42.9%-75% of the cases with higher cognitive disengagement syndrome. However, there was no strong support in favor of associations between cognitive disengagement syndrome and depression and anxiety as a whole. Conclusion: This study provides the first estimates regarding the prevalence and the sociodemographic characteristics of Turkish children with cognitive disengagement syndrome. Cognitive disengagement syndrome seems to be relatively more prevalent in Turkey than in Western cultures. Children whose fathers had a psychiatric disorder, whose mothers had low education, and who were at younger ages should be scrutinized for cognitive disengagement syndrome. [ABSTRACT FROM AUTHOR]

Objective: Pathways associated with glutamate receptors are known to play a role in the pathophysiology of attention-deficit hyperactivity disorder (ADHD). However, cyclin-dependent kinase 5 (CDK5), microtubule-associated protein-2 (MAP2), guanylate kinase-associated protein (GKAP), and postsynaptic density 95 (PSD95), all of which are biomarkers involved in neurodevelopmental processes closely related to glutamatergic pathways, have not previously been studied in patients with ADHD. The main purpose of this study was to evaluate the plasma levels of CDK5, MAP2, GKAP, and PSD95 in children with ADHD and investigate whether these markers have a role in the etiology of ADHD. Methods: Ninety-six children with ADHD between 6 and 15 years of age and 72 healthy controls were included in the study. Five milliliters of blood samples were taken from all participants. The samples were stored at −80°C until analyzed by the enzyme-linked immunosorbent assay method. Results: Statistically significantly lower CDK5 levels were observed in children with ADHD than in healthy controls (p = 0.037). The MAP2, GKAP, and PSD95 levels were found to be statistically significantly higher in the ADHD group than in healthy controls (p = 0.012, p = 0.009, and p = 0.024, respectively). According to binary regression analysis, CDK5 and MAP2 levels were found to be predictors of ADHD. Conclusion: In conclusion, we found that a close relationship existed between ADHD and glutamatergic pathways, and low levels of CDK5 and high levels of MAP2 and GKAP played a role in the etiopathogenesis of ADHD. [ABSTRACT FROM AUTHOR]

Psychiatric disorders can be observed in children and adolescents following an earthquake, with both risk factors and protective factors influencing the development of these disorders. This review aims to compile studies examining the relationship between earthquakes and resilience in children and adolescents after the earthquake disaster in Türkiye. 113 articles were identified using the PubMed database and relevant keywords. After excluding irrelevant studies, 24 that were related to the topic were included in the review. 66.6% of the studies were conducted in China, with 41.6% of total studies having a longitudinal design. In our country, no study was found in this context. Resilience levels were lower in females than males. Resilience was found to be protective against depression, anxiety, and post-traumatic stress disorder, and was positively correlated with social support. High resilience was also associated with significant posttraumatic growth. However, it is not conclusive that all therapy and intervention programs related to resilience are effective. Protecting the mental health of children and adolescents, who are vulnerable and exposed to dangers following an earthquake, is crucial. Identifying protective factors for mental health, particularly resilience, and developing intervention methods for routine and field use to enhance resilience are vital to prevent the development of mental illnesses. [ABSTRACT FROM AUTHOR]

Objective: The COVID-19 pandemic continues to affect physical health as well as mental health in children and adolescents. In this study, we aimed to investigate the state, trait, separation anxiety, and sleep disturbances in the children of health professionals in the first and third waves of the pandemic. Method: 33 children of health professionals and 42 children whose parents were not health professionals were included in the study. Sociodemographic data form, The State-Trait Anxiety Inventory (STAI), Separation Anxiety Assessment Scale- Child Version (SAAS-C), The Sleep Disturbance Scale for Children (SDSC) were used for assessment each for the first and third waves of the pandemic. Results: The state, trait anxiety, and SAAS-C scores of the children of health professionals were higher than the control group in the first wave of the pandemic, state anxiety and SAAS-C scores were still higher than controls in the third wave. Positive correlations were found between the STAI and SAAS-C scores with the working hours of mothers in the pandemic. State anxiety, and SAAS-C scores were higher in children of healthcare workers with a history of COVID-19. Discussion: STAI and SAAS-C scores were found to be higher in the children of health professionals compared to the control group in the first and third wave of the pandemic. There was no effect being children of healthcare workers on SDSC scores. Anxiety levels were related to the time the mother worked during the pandemic and the parent's history of COVID-19. [ABSTRACT FROM AUTHOR]