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4. Bioelectrical impedance analysis in heart transplantation: Early and late changes

Author

STELLATO D, CIRILLO M, DE SANTO LS, FRANGIOSA A, COTRUFO M, DE SANTO NG, DI IORIO BRELATED ARTICLES, LINKS, ANASTASIO, Pietro, D, Stellato, Cirillo, M., SANTO LS, De, P, Anastasio, A, Frangiosa, M, Cotrufo, SANTO NG, De, B, DI IORIO, Stellato, D, Cirillo, M, DE SANTO, Luca Salvatore, Anastasio, Pietro, Frangiosa, A, Cotrufo, M, DE SANTO, Ng, DI IORIO BRELATED, Article, and Links

Subjects
Adult, Male, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Body water, Reactance, Biology, Body Water, Heart Conduction System, Internal medicine, Extracellular fluid, Electric Impedance, medicine, Humans, Heart Failure, Heart transplantation, Analysis of Variance, Body Weight, Normal level, Middle Aged, Surgery, Transplantation, Membrane function, Nephrology, Cardiology, Heart Transplantation, Female, Extracellular Space, Bioelectrical impedance analysis
Abstract

The objectives of this study were to perform bioelectrical impedance analysis before and after heart transplantation with comparison to healthy subjects. Eight patients (7 men, 1 woman) before (day 0) and after transplantation (day 3, 7, 12, 15, and 180) and 24 healthy controls, matched for sex, age, and body mass were studied. Data collection included bioelectrical impedance analysis (resistance, reactance, and estimates of body water), clinical, and laboratory measurements. Compared with controls, patients had at baseline significantly higher reactance, not significantly different resistance, body weight, total body water, and intra- to extracellular water ratio. After surgery, for reactance, there was an acute decrease followed by a slow, progressive increase up to normal level by day 15. Resistance and body weight did not significantly change; the intra- to extracellular water ratio significantly decreased with stable total body water. Changes in reactance are the main effects induced on bioelectrical impedance by heart transplantation. Acutely, there is a large decrease which likely reflects changes both in water distribution and in cell membrane function. The late changes more likely reflect the shift of body water from the extra- to the intracellular space with stable total body water.

Published
2001

5. Reply to Petricevic et al

Author

De Santo LS, Amarelli C, Scardone M, Romano G, DE SANTO, Luca Salvatore, Amarelli, C, Scardone, M, and Romano, G

Published
2013

11. Alterazioni dei fattori di crescita e modulazione del fenotipo cellulare: eventi precoci della malattia dell'aorta ascendente. Parallelo tra valvola aortica tricuspide versus bicuspide

Author

DELLA CORTE, Alessandro, BANCONE C, GROSSI M, GALDERISI, Umberto, CIPOLLARO, Marilena, DE SANTO LS, PIROZZI F, NAPPI, Gianantonio, FORTE A., DE FEO, Marisa, DELLA CORTE, Alessandro, Bancone, C, Grossi, M, DE FEO, Marisa, Galderisi, Umberto, Cipollaro, Marilena, DE SANTO, Luca Salvatore, Pirozzi, F, Nappi, Gianantonio, and Forte, A.

Published
2011

13. Comunicazione orale: Trapianto cardiaco non complicato in paziente con infezione da HIV

Author

Maiello C, Pinto D, Sbreglia C, LIMONGELLI, Giuseppe, Amarelli C, Perrella A, Romano G, Marra C, Pacileo G, De Santo LS, UTILI, Riccardo, DURANTE MANGONI, Emanuele, Maiello, C, Pinto, D, Sbreglia, C, Limongelli, Giuseppe, Amarelli, C, Perrella, A, Romano, G, Marra, C, Pacileo, G, DE SANTO, Luca Salvatore, Utili, Riccardo, and DURANTE MANGONI, Emanuele

Published
2011

14. Insufficienza renale acuta dopo chirurgia cardiaca: prevedibile?

Author

DE SANTO LS, ROMANO G, AMARELLI C, DELLA CORTE, Alessandro, BANCONE C, CAROZZA A, TORELLA M, PETRONE G, NAPPI, Gianantonio, DE FEO, Marisa, DE SANTO, Luca Salvatore, Romano, G, Amarelli, C, DE FEO, Marisa, DELLA CORTE, Alessandro, Bancone, C, Carozza, A, Torella, M, Petrone, G, and Nappi, Gianantonio

Published
2011

15. Off pump versus on-pump CADG su pazienti ad alto rischio operatorio: a confronto l'esperienza del singolo chirurgo

Author

DE FEO, Marisa, BANCONE C, DELLA CORTE, Alessandro, AMARELLI C, DE SANTO LS, CERASUOLO F, PIROZZI F, TORELLA, Michele, BORRELLI M, CITARELLA AG, BUONOCORE M, LA MARCA F, NAPPI, Gianantonio, DE FEO, Marisa, Bancone, C, DELLA CORTE, Alessandro, Amarelli, C, DE SANTO, Luca Salvatore, Cerasuolo, F, Pirozzi, F, Torella, Michele, Borrelli, M, Citarella, Ag, Buonocore, M, LA MARCA, F, and Nappi, Gianantonio

Published
2010

28. New Insights in the Mechanisms of Smooth Muscle Cell Apoptosis in Ascending Aortic Dilatation with Bicuspid and Tricuspid Aortic Valve Stenosis: Possible Key-Role of Cell-Matrix Interactions

Author

DELLA CORTE, Alessandro, Quarto C, Castaldo C, Di Meglio F, Nurzynska D, De Santo LS, DE FEO, Marisa, Scardone M, Montagnani S, Cotrufo M., DELLA CORTE, Alessandro, Quarto, C, Castaldo, C, Di Meglio, F, Nurzynska, D, DE SANTO, Luca Salvatore, DE FEO, Marisa, Scardone, M, Montagnani, S, and Cotrufo, M.

Published
2007

29. Preemptive strategy for the treatment of CMV infection. Lights and shadows on a 8 year single-centre experience of 260 patients

Author

UTILI, Riccardo, Amarelli C, Romano GP, De Santo LS, Marra C, Ursomando F, Mastroianni C, Casillo R, Ragone E, Maiello C, Cotrufo M., DURANTE MANGONI, Emanuele, Utili, Riccardo, Amarelli, C, Romano, Gp, DE SANTO, Luca Salvatore, Marra, C, Ursomando, F, Mastroianni, C, DURANTE MANGONI, Emanuele, Casillo, R, Ragone, E, Maiello, C, and Cotrufo, M.

Abstract

Abs #P180

Published
2007

35. Spatial patterns of matrix proteins expression in dilated ascending aorta with aortic regurgitation: congenital bicuspid valve versus Marfan's sindrome

Author

DELLA CORTE A, DE SANTO LS, QUARTO C, ROMANO G, AMARELLI C, SCARDONE M, DE FEO M, COTRUFO M, CAIANELLO G., MONTAGNANI, STEFANIA, DELLA CORTE, A, DE SANTO, L, Montagnani, Stefania, Quarto, C, Romano, G, Amarelli, C, Scardone, M, DE FEO, M, Cotrufo, M, and Caianello, G.

Abstract

BACKGROUND AND AIM OF THE STUDY: Aortic wall stress has been shown to increase locally at the convex aspect of the ascending tract when axial root motion is increased, as occurs in aortic valve regurgitation. The study aim was to assess the expression of extracellular matrix (ECM) proteins involved in stress-induced vascular remodeling in the convexity and the concavity of dilated ascending aortas with aortic valve regurgitation. METHODS: Aortic wall specimens, harvested at the convexity and concavity of eight dilated ascending aortas with severe aortic valve regurgitation underwent morphometry, Western blot, RT-PCR and confocal immunohistochemistry. Five patients (group A) had congenital bicuspid aortic valve (BAV), and three (group B) had Marfan's syndrome. Specimens from the aorta of three multi-organ donors served as controls. RESULTS: At morphometry, medial degeneration was more severe in the convexity than in the concavity, especially in group A. Western blot, RT-PCR and immunohistochemistry disclosed an asymmetric pattern in the expression of some ECM proteins (laminin, tenascin, fibronectin). Fibronectin was increased in the convexity of both groups compared to controls at Western blot. Immunohistochemistry confirmed this pattern only in BAV. Higher levels of tenascin were found in the convexity in group A. The laminin content was greater in the concavity than in the convexity of both groups, but in group B the type of laminin was different, with the beta2 chain particularly expressed, and almost absent in non-Marfan patients. Type I and type III collagens were more markedly reduced in the convexity than in the concavity in BAV. In group B, type I collagen was decreased and type III increased, but without any significant difference between the two aspects of the aorta. CONCLUSION: A tissue remodeling response to valve disease-related wall stress may underlie aortic dilatation with BAV regurgitation. Although morphometry showed similar changes in Marfan aortas, molecular investigations differentiated this condition, qualitatively, from BAV.

Published
2006

41. Total body protection during surgical procedures on the aortic arch

Author

Scardone M, De Santo LS, DELLA CORTE, Alessandro, Romano G, SANTE', Pasquale, Biondi A, DE FEO, Marisa, Cotrufo M., Scardone, M, DE SANTO, Luca Salvatore, DELLA CORTE, Alessandro, Romano, G, Sante', Pasquale, Biondi, A, DE FEO, Marisa, and Cotrufo, M.

Published
2004

42. Different patterns of extracellulare matrix remodeling in the convexity and concavity of the dilated aorta with bicuspid aortic valve disease

Author

DELLA CORTE, Alessandro, DE SANTO LS, QUARTO C, ROMANO G, AMARELLI C, SCARDONE M, DI MEGLIO F, GUERRA G, SCARANO M, VITALE S, CASTALDO C, MONTAGNINI S, COSTANZA S, COTRUFO M., DE FEO, Marisa, DELLA CORTE, Alessandro, DE SANTO, Luca Salvatore, Quarto, C, DE FEO, Marisa, Romano, G, Amarelli, C, Scardone, M, Di Meglio, F, Guerra, G, Scarano, M, Vitale, S, Castaldo, C, Montagnani, S, Costanza, S, Cotrufo, M., DI MEGLIO, F, and Montagnini, S

Published
2004

44. Protezione multiorgano in corso di chirurgia dell'arco aortico

Author

FRANCIULLI MC, DE SANTO LS, ROMANO G, GIANNOLO B, SANTE', Pasquale, DE FEO, Marisa, CAROZZA A, URSOMANDO F, QUARTO C., Franciulli, Mc, DE SANTO, Luca Salvatore, Romano, G, Giannolo, B, Sante', Pasquale, DE FEO, Marisa, Carozza, A, Ursomando, F, and Quarto, C.

Published
2004

46. Redo surgery on the ascending aorta: indications, procedures and results

Author

Scardone M, Petraio A, R. Bellitti, De Santo LS, Romano G, DE FEO, Marisa, Amarelli C, Cotrufo M., DELLA CORTE, Alessandro, Scardone, M, Petraio, A, Bellitti, R, DE SANTO, Luca Salvatore, Romano, G, DE FEO, Marisa, Amarelli, C, DELLA CORTE, Alessandro, Cotrufo, M., and R., Bellitti

Published
2004

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