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2. Host transcriptomics and machine learning for secondary bacterial infections in patients with COVID-19: a prospective, observational cohort study

Author

Carney, Meagan, Pelaia, Tiana M, Chew, Tracy, Teoh, Sally, Phu, Amy, Kim, Karan, Wang, Ya, Iredell, Jonathan, Cirmena, Gabriella, Ballestrero, Alberto, Cripps, Allan, Cox, Amanda, De Maria, Andrea, Kulasinghe, Arutha, Feng, Carl, Chaussabel, Damien, Rinchai, Darawan, Bedognetti, Davide, Zoppoli, Gabriele, Gunawan, Gunawan, Thevarajan, Irani, Audsley, Jennifer, Eden, John-Sebastian, Kralovcova, Marcela, Nalos, Marek, Radic, Marko, Matejovic, Martin, Bedognetti, Michele, Prucha, Miroslav, Toufiq, Mohammed, Teluguakula, Narasaraju, West, Nicholas, Cremonesi, Paolo, Britton, Philip, Branco, Ricardo G, Bilyy, Rostyslav, MacDonald, Stephen, Karvunidis, Thomas, Kwan, Tim, Herwanto, Velma, Kuan, Win Sen, Zerbib, Yoann, McLean, Anthony, Schughart, Klaus, Tang, Benjamin, Shojaei, Maryam, Short, Kirsty R, and Pelaia, Tiana Maria

Published
2024
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3. Intermediate monocytes expansion and homing markers expression in COVID-19 patients associate with kidney dysfunction

Author

Dentone, Chiara, Fenoglio, Daniela, Parodi, Alessia, Altosole, Tiziana, Di Biagio, Antonio, Bozzano, Federica, Nasi, Giorgia, Vena, Antonio, Fabbi, Marina, Ferrera, Francesca, Bruzzone, Bianca, Giacomini, Mauro, Giacobbe, Daniele Roberto, Pelosi, Paolo, De Maria, Andrea, Bassetti, Matteo, De Palma, Raffaele, and Filaci, Gilberto

Published
2023
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7. Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop

Author

Bedognetti, Davide, Ceccarelli, Michele, Galluzzi, Lorenzo, Lu, Rongze, Palucka, Karolina, Samayoa, Josue, Spranger, Stefani, Warren, Sarah, Wong, Kwok-Kin, Ziv, Elad, Chowell, Diego, Coussens, Lisa M, De Carvalho, Daniel D, DeNardo, David G, Galon, Jérôme, Kaufman, Howard L, Kirchhoff, Tomas, Lotze, Michael T, Luke, Jason J, Minn, Andy J, Politi, Katerina, Shultz, Leonard D, Simon, Richard, Thórsson, Vésteinn, Weidhaas, Joanne B, Ascierto, Maria Libera, Ascierto, Paolo Antonio, Barnes, James M, Barsan, Valentin, Bommareddy, Praveen K, Bot, Adrian, Church, Sarah E, Ciliberto, Gennaro, De Maria, Andrea, Draganov, Dobrin, Ho, Winson S, McGee, Heather M, Monette, Anne, Murphy, Joseph F, Nisticò, Paola, Park, Wungki, Patel, Maulik, Quigley, Michael, Radvanyi, Laszlo, Raftopoulos, Harry, Rudqvist, Nils-Petter, Snyder, Alexandra, Sweis, Randy F, Valpione, Sara, Zappasodi, Roberta, Butterfield, Lisa H, Disis, Mary L, Fox, Bernard A, Cesano, Alessandra, and Marincola, Francesco M

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Immunology, Cancer, Women's Health, Human Genome, Genetics, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Generic health relevance, Good Health and Well Being, Advisory Committees, Animals, Biomarkers, Tumor, Congresses as Topic, Disease Models, Animal, Humans, Immunotherapy, Medical Oncology, Neoplasms, Societies, Medical, Treatment Outcome, Tumor Microenvironment, Cancer immune responsiveness, Immune checkpoint inhibitor, Immune oncology, Tumor microenvironment, Tumor mutational burden, Immunogenic cell death, Biomarker, Germline molecular alterations, Somatic molecular alterations, Cancer immune phenotype, Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task Force and Working Groups, Oncology and carcinogenesis
Abstract

Tumor immunology has changed the landscape of cancer treatment. Yet, not all patients benefit as cancer immune responsiveness (CIR) remains a limitation in a considerable proportion of cases. The multifactorial determinants of CIR include the genetic makeup of the patient, the genomic instability central to cancer development, the evolutionary emergence of cancer phenotypes under the influence of immune editing, and external modifiers such as demographics, environment, treatment potency, co-morbidities and cancer-independent alterations including immune homeostasis and polymorphisms in the major and minor histocompatibility molecules, cytokines, and chemokines. Based on the premise that cancer is fundamentally a disorder of the genes arising within a cell biologic process, whose deviations from normality determine the rules of engagement with the host's response, the Society for Immunotherapy of Cancer (SITC) convened a task force of experts from various disciplines including, immunology, oncology, biophysics, structural biology, molecular and cellular biology, genetics, and bioinformatics to address the complexity of CIR from a holistic view. The task force was launched by a workshop held in San Francisco on May 14-15, 2018 aimed at two preeminent goals: 1) to identify the fundamental questions related to CIR and 2) to create an interactive community of experts that could guide scientific and research priorities by forming a logical progression supported by multiple perspectives to uncover mechanisms of CIR. This workshop was a first step toward a second meeting where the focus would be to address the actionability of some of the questions identified by working groups. In this event, five working groups aimed at defining a path to test hypotheses according to their relevance to human cancer and identifying experimental models closest to human biology, which include: 1) Germline-Genetic, 2) Somatic-Genetic and 3) Genomic-Transcriptional contributions to CIR, 4) Determinant(s) of Immunogenic Cell Death that modulate CIR, and 5) Experimental Models that best represent CIR and its conversion to an immune responsive state. This manuscript summarizes the contributions from each group and should be considered as a first milestone in the path toward a more contemporary understanding of CIR. We appreciate that this effort is far from comprehensive and that other relevant aspects related to CIR such as the microbiome, the individual's recombined T cell and B cell receptors, and the metabolic status of cancer and immune cells were not fully included. These and other important factors will be included in future activities of the taskforce. The taskforce will focus on prioritization and specific actionable approach to answer the identified questions and implementing the collaborations in the follow-up workshop, which will be held in Houston on September 4-5, 2019.

Published
2019

8. Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop

Author

Bedognetti, Davide, Ceccarelli, Michele, Galluzzi, Lorenzo, Lu, Rongze, Palucka, Karolina, Samayoa, Josue, Spranger, Stefani, Warren, Sarah, Wong, Kwok-Kin, Ziv, Elad, Chowell, Diego, Coussens, Lisa M, De Carvalho, Daniel D, DeNardo, David G, Galon, Jérôme, Kaufman, Howard L, Kirchhoff, Tomas, Lotze, Michael T, Luke, Jason J, Minn, Andy J, Politi, Katerina, Shultz, Leonard D, Simon, Richard, Thórsson, Vésteinn, Weidhaas, Joanne B, Ascierto, Maria Libera, Ascierto, Paolo Antonio, Barnes, James M, Barsan, Valentin, Bommareddy, Praveen K, Bot, Adrian, Church, Sarah E, Ciliberto, Gennaro, De Maria, Andrea, Draganov, Dobrin, Ho, Winson S, McGee, Heather M, Monette, Anne, Murphy, Joseph F, Nisticò, Paola, Park, Wungki, Patel, Maulik, Quigley, Michael, Radvanyi, Laszlo, Raftopoulos, Harry, Rudqvist, Nils-Petter, Snyder, Alexandra, Sweis, Randy F, Valpione, Sara, Zappasodi, Roberta, Butterfield, Lisa H, Disis, Mary L, Fox, Bernard A, Cesano, Alessandra, and Marincola, Francesco M

Subjects
Biomedical and Clinical Sciences, Immunology, Cancer, Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task Force and Working Groups, Oncology and carcinogenesis
Abstract

Following publication of the original article [1], the author reported that an author name, Roberta Zappasodi, was missed in the authorship list.

Published
2019

9. Navigating secure storage requirements for EUDI Wallets: a review paper.

Author

Ebadi Ansaroudi, Zahra, Sciarretta, Giada, De Maria, Andrea, and Ranise, Silvio

Subjects
ELECTRONIC wallets, MARKETING research, WALLETS, STORAGE
Abstract

The European Digital Identity Wallet (EUDI Wallet) plays a pivotal role in shaping digital identity across the EU, necessitating a secure storage solution compliant with eIDAS2 regulation. In this study, we first analyze mobile secure storage solutions for the EUDI Wallet, identifying any gaps between current offerings and the EUDI Wallet's requirements. Our analysis indicates a significant shortfall in the availability of mobile native solutions, with only approximately 10.5% of mobile phones in the Italian market currently adhering to the stringent requirements mandated by eIDAS2. Consequently, we explore and evaluate alternative design solutions in terms of their feasibility and integration potential. [ABSTRACT FROM AUTHOR]

Published
2025
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11. Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study

Author

Ravera, Francesco, Borea, Roberto, Cirmena, Gabriella, Dameri, Martina, Ferrando, Lorenzo, Gallo, Maurizio, Casini, Cecilia, Fallani, Neri, Stabile, Mario, Barbero, Valentina, Murialdo, Roberto, Tixi, Lucia, Cappuccio, Margherita, Cuboni, Andrea, Sivieri, Irene, Fornarini, Giuseppe, De Maria, Andrea, Ballestrero, Alberto, and Zoppoli, Gabriele

Published
2022
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13. Clinical characteristics, management and in-hospital mortality of patients with coronavirus disease 2019 in Genoa, Italy

Author

Alessandrini, Anna, Camera, Marco, Delfino, Emanuele, De Maria, Andrea, Dentone, Chiara, Di Biagio, Antonio, Dodi, Ferdinando, Ferrazin, Antonio, Mazzarello, Giovanni, Mikulska, Malgorzata, Nicolini, Laura, Toscanini, Federica, Giacobbe, Daniele R., Vena, Antonio, Taramasso, Lucia, Balletto, Elisa, Portunato, Federica, Schenone, Eva, Rosseti, Nirmala, Baldi, Federico, Berruti, Marco, Briano, Federica, Dettori, Silvia, Labate, Laura, Magnasco, Laura, Mirabella, Michele, Pincino, Rachele, russo, Chiara, Sarteschi, Giovanni, sepulcri, Chiara, Tutino, Stefania, Pontremoli, Roberto, Beccati, Valentina, Casciaro, Salvatore, Casu, Massimo, Gavaudan, Francesco, Ghinatti, Maria, Gualco, Elisa, Leoncini, Giovanna, pitto, Paola, salam, Kassem, Gratarola, Angelo, Bixio, Mattia, Amelia, Annalisa, Balestra, Andrea, Ballarino, Paola, Bardi, Nicholas, Boccafogli, Roberto, Caserza, Francesca, Calzolari, Elisa, Castelli, Marta, Cenni, Elisabetta, Cortese, Paolo, Cuttone, Giuseppe, Feltrin, Sara, Giovinazzo, Stefano, Giuntini, Patrizia, Natale, Letizia, Orsi, Davide, Pastorino, Matteo, Perazzo, Tommaso, Pescetelli, Fabio, Schenone, Federico, Serra, Maria G., Sottano, Marco, Tallone, Roberto, Amelotti, Massimo, Majabò, Marie J., Merlini, Massimo, Perazzo, Federica, Ahamd, Nidal, Barbera, Paolo, Bovio, Marta, Campodonico, Paola, Collidà, Andrea, Cutuli, Ombretta, Lomeo, Agnese, Fezza, Francesca, Gentilucci, Nicola, Hussein, Nadia, Malvezzi, Emanuele, Massobrio, Laura, Motta, Giula, Pastorino, Laura, Pollicardo, Nicoletta, Sartini, Stefano, Vacca, Paola, Virga, Valentina, Porto, Italo, Bezante, Giampaolo, Della Bona, Roberta, La Malfa, Giovanni, Valbusa, Alberto, Ad, Vered G., Barisione, Emanuela, Bellotti, Michele, Teresita, Aloe’, Blanco, Alessandro, Grosso, Marco, Piroddi, Maria Grazia, Moscatelli, Paolo, Caiti, Matteo, Magnani, Ottavia, Sukkar, Samir, Cogorno, Ludovica, Gradaschi, Raffaella, Guiddo, Erica, Martino, Eleonora, Pisciotta, Livia, Cavagliere, Bruno, Cristina, Rossi, Francesca, Farina, Garibotto, Giacomo, Esposito, Pasquale, Bellezza, Carmen, Harusha, Emirjona, Rossi, Francesca, Arboscello, Eleonora, Arzani, Laura, De Mattei, Laura, Spadaro, Marzia, Passalacqua, Giovanni, Bagnasco, Diego, Braido, Fulvio, Riccio, Annamaria, Tagliabue, Elena, Gustavino, Claudio, Ferraiolo, Antonella, Monacelli, Fiammetta, Mahmoud, Mona, Tagliafico, Luca, Napolitano, Armando, Fiorio, Maria, Pizzonia, Monica, Giannotti, Chiara, Nencioni, Alessio, Giuffrida, Salvatore, Rosso, Nicola, Morando, Alessandra, Papalia, Riccardo, Passerini, Donata, Tiberio, Gabriella, Orengo, Giovanni, Battaglini, Alberto, Ruffoni, Silvano, Caglieris, Sergio, Giacobbe, Daniele Roberto, Ball, Lorenzo, Brunetti, Iole, Loconte, Maurizio, Patroniti, Nicolò A., Robba, Chiara, Bavastro, Martina, Cerchiaro, Matteo, Giacomini, Mauro, Mora, Sara, Sepulcri, Chiara, Russo, Chiara, Pelosi, Paolo, and Bassetti, Matteo

Published
2020
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14. Clinical Benefits of the Socket Shield Technique Associated with Anatomical Transmucosal Implant Components: A Case Report.

Author

Morello, Marco, Poglio, Enrico, De Maria, Andrea, and Bresciano, Mario

Subjects
DENTAL implants, PROSTHETICS, COMPUTER-assisted surgery, COSMETIC dentistry, GUMS & resins, TREATMENT effectiveness, POLYTEF, REHABILITATION, DATA analysis software, PATIENT care, DIGITAL diagnostic imaging
Abstract

One of the key factors in determining the esthetic success of implant-supported prostheses in the esthetic zone is the preservation of the natural architecture of the peri-implant tissues. The present case replaces two maxillary lateral incisors with reduced buccal cortical bone by means of implant-supported crowns. The socket shield technique was adopted to conserve the tissue volume, guided surgery was used to manage optimal implant insertion, and anatomically shaped transmucosal implant components were selected to shape peri-implant soft tissues with ideal emergence profiles and allow direct digital impressions without scan bodies. The combination of immediate implants, guided surgery, the socket shield technique, anatomically shaped transmucosal implant components, and digital impressions without scan bodies was used to achieve a successful rehabilitation with healthy, stable, and anatomically shaped peri-implant tissues. [ABSTRACT FROM AUTHOR]

Published
2023
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16. Bronchoalveolar lavage fluid characteristics and outcomes of invasively mechanically ventilated patients with COVID-19 pneumonia in Genoa, Italy

Author

Dentone, Chiara, Vena, Antonio, Loconte, Maurizio, Grillo, Federica, Brunetti, Iole, Barisione, Emanuela, Tedone, Elisabetta, Mora, Sara, Di Biagio, Antonio, Orsi, Andrea, De Maria, Andrea, Nicolini, Laura, Ball, Lorenzo, Giacobbe, Daniele Roberto, Magnasco, Laura, Delfino, Emanuele, Mastracci, Luca, Mangerini, Rosa, Taramasso, Lucia, Sepulcri, Chiara, Pincino, Rachele, Bavastro, Martina, Cerchiaro, Matteo, Mikulska, Malgorzata, Bruzzone, Bianca, Icardi, Giancarlo, Frisoni, Paolo, Gratarola, Angelo, Patroniti, Nicolò, Pelosi, Paolo, and Bassetti, Matteo

Published
2021
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17. CD34+DNAM-1brightCXCR4+ haemopoietic precursors circulate after chemotherapy, seed lung tissue and generate functional innate-like T cells and NK cells

Author

Perrone, Carola, primary, Bozzano, Federica, additional, Dal Bello, Maria Giovanna, additional, Del Zotto, Genny, additional, Antonini, Francesca, additional, Munari, Enrico, additional, Maggi, Enrico, additional, Moretta, Francesca, additional, Farshchi, Alireza Hajabbas, additional, Pariscenti, Gianluca, additional, Tagliamento, Marco, additional, Genova, Carlo, additional, Moretta, Lorenzo, additional, and De Maria, Andrea, additional

Published
2024
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18. Post-SARS-CoV-2 infection and post-vaccine-related neurological complications share clinical features and the same positivity to anti-ACE2 antibodies.

Author

Bellucci, Margherita, Bozzano, Federica Maria, Castellano, Chiara, Pesce, Giampaola, Beronio, Alessandro, Farshchi, Alireza Hajabbas, Limongelli, Alessandro, Uccelli, Antonio, Benedetti, Luana, and De Maria, Andrea

Subjects
POST-acute COVID-19 syndrome, PERIPHERAL nervous system, COVID-19, NEUROLOGICAL disorders, NEUROLOGIC manifestations of general diseases, MYELITIS
Abstract

Introduction: A potential overlap in symptoms between post-acute COVID-19 syndrome and post-COVID-19 vaccination syndrome has been noted. We report a paired description of patients presenting with similar manifestations involving the central (CNS) or peripheral nervous system (PNS) following SARS-CoV-2 infection or vaccination, suggesting that both may have triggered similar immune-mediated neurological disorders in the presence of anti-idiotype antibodies directed against the ACE2 protein. Patients and methods: Four patients exhibited overlapping neurological manifestations following SARS-CoV-2 infection or vaccination: radiculitis, Guillain -- Barré syndrome, and MRI-negative myelitis, respectively, sharing positivity for anti-ACE2 antibodies. Autoantibodies against AQP-4, MOG, GlyR, GAD, and amphiphysin, onconeural antibodies for CNS syndromes, and anti-ganglioside antibodies for PNS syndromes tested negative in all patients. Discussion: Anti-idiotype antibodies against ACE2 have been detected in patients who recovered from COVID-19 infection, and it has been hypothesized that such antibodies may mediate adverse events following SARS-CoV-2 infection or vaccination, resulting in the activation of the immune system against cells expressing ACE2, such as neurons. Our data reveal clinically overlapping syndromes triggered by SARS-CoV-2 infection or vaccination, sharing positivity for anti-ACE2 antibodies. Their presence, in the absence of other classic autoimmune markers of CNS or PNS involvement, suggests that they might play an active role in the context of an aberrant immune response. Conclusion: Anti-idiotype antibodies directed against ACE2 may be triggered by both SARS-CoV-2 infection and vaccination, possibly contributing to neurological autoimmune manifestations. Their pathogenic role, however, remains to be demonstrated in large-scale, more structured studies. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Neutralizing monoclonal antibodies for the prevention of severe COVID-19: a retrospective study during Omicron BA.1 variant surge.

Author

Bartalucci, Claudia, Limongelli, Alessandro, Nicolini, Laura Ambra, Ponzano, Marta, Tigano, Stefania, Farinella, Sara Tita, Carrega, Giuliana, Malerba, Gemma, Magnè, Federica, Balletto, Elisa, Giacobbe, Daniele Roberto, Riccio, Giovanni, Cenderello, Giovanni, Taramasso, Lucia, Bruzzone, Bianca, Vena, Antonio, Di Biagio, Antonio, Mikulska, Malgorzata, De Maria, Andrea, and Dentone, Chiara

Published
2024
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20. Clinical and Radiologic Evaluation of a Fully Tapered Implant with Immediate Placement in the Esthetic Zone: A Prospective Case Series Study.

Author

Cardaropoli, Daniele, Tamagnone, Lorenzo, Roffredo, Alessandro, and De Maria, Andrea

Subjects
DENTAL implants, BONE resorption, TIME, COSMETIC dentistry, CASE studies, DENTAL fillings, LONGITUDINAL method, OSSEOINTEGRATION
Abstract

A fully tapered implant was recently introduced to increase primary stability and to be used in challenging situations. Twenty single implants were inserted in maxillary postextraction sockets, from premolar to premolar, and immediately restored. Marginal bone level (MBL) and probing depth (PD) were evaluated over a 12-month follow-up period. All implants osseointegrated, achieving a success rate of 100%. The difference in MBL between implant placement and 1 year later was 0.20 ± 0.04 mm, while PD was 2.82 ± 0.51 mm at 1 year. The data reported here support the use of a fully tapered implant for immediate placement and immediate provisionalization for single-tooth replacements in the esthetic area. [ABSTRACT FROM AUTHOR]

Published
2022
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28. CD34+DNAM-1brightCXCR4+ haemopoietic precursors circulate after chemotherapy, seed lung tissue and generate functional innate-like T cells and NK cells.

Author

Perrone, Carola, Bozzano, Federica, Dal Bello, Maria Giovanna, Del Zotto, Genny, Antonini, Francesca, Munari, Enrico, Maggi, Enrico, Moretta, Francesca, Farshchi, Alireza Hajabbas, Pariscenti, Gianluca, Tagliamento, Marco, Genova, Carlo, Moretta, Lorenzo, and De Maria, Andrea

Subjects
KILLER cells, T cells, CXCR4 receptors, CHEMOKINE receptors, BONE marrow, GINGER
Abstract

Background: There is little information on the trajectory and developmental fate of Lin-CD34+DNAM-1bright CXCR4+ progenitors exiting bone marrow during systemic inflammation. Objective: To study Lin-CD34+DNAM-1bright CXCR4+ cell circulation in cancer patients, to characterize their entry into involved lung tissue and to characterize their progenies. Methods: Flow cytometric analysis of PBMC from 18 patients with lung cancer on samples collected immediately before the first and the second treatment was performed to study Lin-CD34+DNAM-1bright CXCR4+ precursors. Precursors were purified (>99%) and cultured in vitro from all patients. Paired PBMC and tissue samples from patients undergoing tumor resection were analyzed by flow cytometry to assess tissue entry and compare phenotype and developmental potential of Lin-CD34+DNAM-1bright CXCR4+ cells in both compartments. Results: Significant circulation of Lin-CD34+DNAM-1bright CXCR4+ precursors was observed 20d after the first treatment. Precursors express CXC3CR1, CXCR3, CXCR1 consistent with travel towards inflamed tissues. Flowcytometric analysis of lung tissue samples showed precursor presence in all patients in tumor and neighboring uninvolved areas. Successful purification and in vitro culture from both blood and lung tissue generates a minor proportion of maturing NK cells (<10%) and a predominant proportion (>85%) of a/b T-progenies with innate-like phenotype expressing NKG2D,NKp30,DNAM-1. Innate-like maturing T-cells in vitro are cytotoxic, can be triggered via NKR/TCR co-stimulation and display broad spectrum Th1,Th2 and Th1/Th17 cytokine production. Conclusion: In advanced stage lung cancer CD34+DNAM-1brightCXCR4+ inflammatory precursors increase upon treatment, enter involved tissues, generate functional progenies and may thus represent an additional player contributing to immune balance in the highly SDF-1/CXCR4-biased prometastatic tumor microenvironment. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Impact of a mixed educational and semi-restrictive antimicrobial stewardship project in a large teaching hospital in Northern Italy

Author

Giacobbe, Daniele Roberto, Del Bono, Valerio, Mikulska, Malgorzata, Gustinetti, Giulia, Marchese, Anna, Mina, Federica, Signori, Alessio, Orsi, Andrea, Rudello, Fulvio, Alicino, Cristiano, Bonalumi, Beatrice, Morando, Alessandra, Icardi, Giancarlo, Beltramini, Sabrina, Viscoli, Claudio, Ferrazin, Antonio, Dodi, Ferdinando, Morandi, Norberto, Toscanini, Federica, Camera, Marco, Di Biagio, Antonio, Mazzarello, Giovanni, Alessandrini, Anna Ida, De Maria, Andrea, Delfino, Emanuele, Nicolini, Laura Ambra, Saffioti, Carolina, Magnè, Federica, Gandolfo, Nemo, and On behalf of the San Martino Antimicrobial Stewardship Group

Published
2017
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32. Intermediate monocytes expansion and homing markers expression in COVID-19 patients associate with kidney dysfunction

Author

Dentone, Chiara, primary, Fenoglio, Daniela, additional, Parodi, Alessia, additional, Altosole, Tiziana, additional, Di Biagio, Antonio, additional, Bozzano, Federica, additional, Nasi, Giorgia, additional, Vena, Antonio, additional, Fabbi, Marina, additional, Ferrera, Francesca, additional, Bruzzone, Bianca, additional, Giacomini, Mauro, additional, Giacobbe, Daniele Roberto, additional, Pelosi, Paolo, additional, De Maria, Andrea, additional, Bassetti, Matteo, additional, De Palma, Raffaele, additional, and Filaci, Gilberto, additional

Published
2022
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38. Preservation of Peri-implant Soft Tissues Following Immediate Postextraction Implant Placement. Part II: Clinical Evaluation.

Author

Cardaropoli, Daniele, Tamagnone, Lorenzo, Roffredo, Alessandro, De Maria, Andrea, and Gaveglio, Lorena

Subjects
PERI-implantitis, SOFT tissue injuries, DENTAL extraction, CONNECTIVE tissues, COSMETIC dentistry, DENTAL fillings, DENTAL implants, XENOGRAFTS
Abstract

Soft tissue contour changes were evaluated in 20 patients who underwent immediate implant placement with provisional restoration. The bone-to-implant gap was accurately grafted with xenograft prior to implant placement, and enamel matrix derivative was applied prior to delivery of an immediate screw-retained restoration. No significant differences were observed between baseline and 1 year after implant placement in soft tissue contour measurements and the Pink Esthetic Score. Furthermore, no differences were observed between thin or thick biotypes. It was shown that the use of immediate single-tooth implants with immediate restoration resulted in the maintenance of the soft tissue contour and esthetics when compared to pretreatment independently from the soft tissue phenotype. [ABSTRACT FROM AUTHOR]

Published
2019
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39. Preservation of Peri-implant Hard Tissues Following Immediate Postextraction Implant Placement. Part I: Radiologic Evaluation.

Author

Cardaropoli, Daniele, Tamagnone, Lorenzo, Roffredo, Alessandro, De Maria, Andrea, and Gaveglio, Lorena

Subjects
ALVEOLAR process surgery, MAXILLA surgery, DENTAL metallurgy, BONE resorption, BONE screws, BONE grafting, COMPUTED tomography, DENTAL crowns, DENTAL fillings, PERIODONTITIS, POSTOPERATIVE period, PRESERVATION of organs, tissues, etc., PROSTHETICS, OSSEOINTEGRATION, BONE density, PERI-implantitis, DENTAL implants
Abstract

Immediate implant placement may represent a possible treatment plan for single tooth restoration. This study evaluated the insertion of osseointegrated implants in intact fresh extraction sockets in the anterior maxilla. The bone-toimplant gap was accurately grafted with a bovine bone mineral prior to implant engagement, and an immediate screw-retained restoration was delivered. After 3 months, the provisional crown was replaced with the definitive ceramic crown. Marginal bone levels remained stable after 1 year. The horizontal ridge dimension was also evaluated at three levels using CBCT scans after 1 year. The horizontal width of the postextraction crest was well preserved independently from the thickness of the buccal bone plate at baseline. [ABSTRACT FROM AUTHOR]

Published
2019
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40. Unsung Hero Robert C. Gallo

Author

Abbadessa, Giovanni, Accolla, Roberto, Aiuti, Fernando, Albini, Adriana, Aldovini, Anna, Alfano, Massimo, Antonelli, Guido, Bartholomew, Courtenay, Bentwich, Zvi, Bertazzoni, Umberto, Berzofsky, Jay A., Biberfeld, Peter, Boeri, Enzo, Buonaguro, Luigi, Buonaguro, Franco M., Bukrinsky, Michael, Burny, Arsène, Caruso, Arnaldo, Cassol, Sharon, Chandra, Prakash, Ceccherini-Nelli, Luca, Chieco-Bianchi, Luigi, Clerici, Mario, Colombini-Hatch, Sandra, de Giuli Morghen, Carlo, de Maria, Andrea, de Rossi, Anita, Dierich, Manfred, Della-Favera, Riccardo, Dolei, Antonina, Douek, Daniel, Erfle, Volker, Felber, Barbara, Fiorentin, Simona, Franchini, Genoveffa, Gershoni, Jonathan M., Gotch, Frances, Green, Patrick, Greene, Warner C., Hall, William, Haseltine, William, Jacobson, Stephens, Kallings, Lars O., Kalyanaraman, Vaniambadi S., Katinger, Hermann, Khalili, Kamel, Klein, George, Klein, Eva, Klotman, Mary, Klotman, Paul, Kotler, Moshe, Kurth, Reinhard, Lafeuillade, Alain, la Placa, Michelangelo, Lewis, Jonathan, Lillo, Flavia, Lisziewicz, Julianna, Lomonico, Anita, Lopalco, Lucia, Lor, Franco, Lusso, Paolo, Macchi, Beatrice, Malim, Michael, Margolis, Leonid, Markham, Phillip D., McClure, Myra, Miller, Nancy, Mingari, Maria C., Moretta, Lorenzo, Noonan, Douglas, O'Brien, Steve, Okamoto, Takashi, Pal, Ranajit, Palese, Peter, Panet, Amos, Pantaleo, Giuseppe, Pavlakis, George, Pistello, Mauro, Plotkin, Stanley, Poli, Guido, Pomerantz, Roger, Radaelli, Antonia, Robert-Guroff, Marjorie, Roederer, Mario, Sarangadharan, Mangalasseril G., Schols, Dominique, Secchiero, Paola, Shearer, Gene, Siccardi, Antonio, Stevenson, Mario, Svoboda, Jan, Tartaglia, Jim, Torelli, Giuseppe, Tornesello, Maria Lina, Tschachler, Erwin, Vaccarezza, Mauro, Vallbracht, Angelika, van Lunzen, Jan, Varnier, Oliviero, Vicenzi, Elisa, von Melchner, Harald, Witz, Issac, Zagury, Daniel, Zagury, Jean-Francois, Zauli, Giorgio, and Zipeto, Donato

Published
2009

41. Persistence of Unintegrated HIV DNA Associates With Ongoing NK Cell Activation and CD34+DNAM-1brightCXCR4+ Precursor Turnover in Vertically Infected Patients Despite Successful Antiretroviral Treatment

Author

Taramasso, Lucia, primary, Bozzano, Federica, additional, Casabianca, Anna, additional, Orlandi, Chiara, additional, Bovis, Francesca, additional, Mora, Sara, additional, Giacomini, Mauro, additional, Moretta, Lorenzo, additional, Magnani, Mauro, additional, Di Biagio, Antonio, additional, and De Maria, Andrea, additional

Published
2022
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42. Additional file 3 of Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study

Author

Ravera, Francesco, Borea, Roberto, Cirmena, Gabriella, Dameri, Martina, Ferrando, Lorenzo, Gallo, Maurizio, Casini, Cecilia, Fallani, Neri, Stabile, Mario, Barbero, Valentina, Murialdo, Roberto, Tixi, Lucia, Cappuccio, Margherita, Cuboni, Andrea, Sivieri, Irene, Fornarini, Giuseppe, De Maria, Andrea, Ballestrero, Alberto, and Zoppoli, Gabriele

Abstract

Additional file 3: Figure S3. CYBERSORT analysis of PBMCs transcripts of samples collected from the two selected patients at baseline (T1), 2 months (T2), and 7 months (T3).

Published
2022
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44. Reactivation of Herpes Simplex Virus Type 1 (HSV-1) Detected on Bronchoalveolar Lavage Fluid (BALF) Samples in Critically Ill COVID-19 Patients Undergoing Invasive Mechanical Ventilation: Preliminary Results from Two Italian Centers

Author

Giacobbe, Daniele Roberto, primary, Di Bella, Stefano, additional, Dettori, Silvia, additional, Brucci, Giorgia, additional, Zerbato, Verena, additional, Pol, Riccardo, additional, Segat, Ludovica, additional, D’Agaro, Pierlanfranco, additional, Roman-Pognuz, Erik, additional, Friso, Federica, additional, Principe, Luigi, additional, Lucangelo, Umberto, additional, Ball, Lorenzo, additional, Robba, Chiara, additional, Battaglini, Denise, additional, De Maria, Andrea, additional, Brunetti, Iole, additional, Patroniti, Nicolò, additional, Briano, Federica, additional, Bruzzone, Bianca, additional, Guarona, Giulia, additional, Magnasco, Laura, additional, Dentone, Chiara, additional, Icardi, Giancarlo, additional, Pelosi, Paolo, additional, Luzzati, Roberto, additional, and Bassetti, Matteo, additional

Published
2022
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45. Incidence and Immunomic Features of Apyretic COVID-19 in Patients Affected by Solid Tumors: a Prospective Cohort Study.

Author

Ravera, Francesco, primary, Borea, Roberto, additional, Cirmena, Gabriella, additional, Dameri, Martina, additional, Ferrando, Lorenzo, additional, Gallo, Maurizio, additional, Casini, Cecilia, additional, Fallani, Neri, additional, Barbero, Valentina, additional, Murialdo, Roberto, additional, Tixi, Lucia, additional, Cappuccio, Margherita, additional, Cuboni, Andrea, additional, Sivieri, Irene, additional, Fornarini, Giuseppe, additional, De Maria, Andrea, additional, Ballestrero, Alberto, additional, and Zoppoli, Gabriele, additional

Published
2022
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49. Alveolar Ridge Preservation Using Tridimensional Collagen Matrix and Deproteinized Bovine Bone Mineral in the Esthetic Area: A CBCT and Histologic Human Pilot Study.

Author

Cardaropoli, Daniele, Tamagnone, Lorenzo, Roffredo, Alessandro, De Maria, Andrea, and Gaveglio, Lorena

Subjects
ALVEOLAR process surgery, COLLAGEN, DENTAL implants, COSMETIC dentistry, CONE beam computed tomography, HISTOLOGY, BONE grafting
Abstract

Alveolar ridge preservation is of great importance for successful implant therapy. This study investigated the effects of a xenogeneic tridimensional collagen matrix (CM) in conjunction with deproteinized bovine bone mineral blended with 10% collagen (DBBM-C) on the healing of 12 intact extraction sockets in the esthetic area. Cone beam computed tomograpy examinations revealed nearly stable alveolar ridge dimensions (> 90% of the ridge horizontal dimension was preserved). New bone formation of approximately 45% and adequate resorption of the grafted material were histologically observed. Thus, application of CM together with DBBM-C using minimally invasive flapless approach can preserve the original ridge volume and support bone formation, contributing to adequate bone volume for implant insertion. [ABSTRACT FROM AUTHOR]

Published
2018
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