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297 results on '"DE AGUIAR, MARIA CÁSSIA FERREIRA"'

3. MONONUCLEOSIS ASSOCIATED WITH CUTANEOUS ERUPTIONS.

Author

MEIRELLES, Daniela Pereira, primary, SANT´ANA, Maria Sissa Pereira, additional, FELIX, Fernanda Aragão, additional, OLIVEIRA, Sicilia Rezende, additional, CALDEIRA, Patrícia Carlos, additional, and de AGUIAR, Maria Cássia Ferreira, additional

Published
2024
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16. CUTANEOUS AMYLOIDOSIS DIAGNOSED BY ORAL MANIFESTATION

Author

Tavares, Thalita Soares, primary, Da Costa, Adriana Aparecida Silva, additional, Meirelles, Daniela Pereira, additional, De Aguiar, Maria Cássia Ferreira, additional, Mesquita, Ricardo Alves, additional, Da Silva, Tarcília Aparecida, additional, and Caldeira, Patrícia Carlos, additional

Published
2022
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17. PLASMABLASTIC LYMPHOMA OF THE PALATE

Author

Da Costa, Adriana Aparecida Silva, primary, Tavares, Thalita Soares, additional, Meirelles, Daniela Pereira, additional, Fonseca, Felipe Paiva, additional, De Almeida, Oslei Paes, additional, De Aguiar, Maria Cássia Ferreira, additional, and Caldeira, Patrícia Carlos, additional

Published
2022
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21. An exophytic growth over the alveolar ridge

Author

da Costa, Adriana Aparecida Silva, primary, Tavares, Thalita Soares, additional, Meirelles, Daniela Pereira, additional, Caldeira, Patrícia Carlos, additional, Barcelos, Natália Santos, additional, de Oliveira, Eduardo Morato, additional, Milagres, Roselaine Moreira Coelho, additional, and de Aguiar, Maria Cássia Ferreira, additional

Published
2022
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23. A symptomatic swelling of the upper lip

Author

Vasconcelos, Ana Carolina Uchoa, Loyola, Adriano Mota, Gomes, Ana Paula Neutzling, de Araújo, Vera Cavalcanti, Tarquínio, Sandra Beatriz Chaves, Silveira, Felipe Martins, and de Aguiar, Maria Cássia Ferreira

Published
2018
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25. Clinical and demographic features of minor salivary gland tumors: A collaborative study of 480 cases.

Author

Bruzinga, Fábio Fernandes Borém, Fernandes, Fernanda Carvalho Fulgêncio, Dias, Fernanda Ribeiro, Lima, Marla Gabriela, de Souza, Paulo Eduardo Alencar, de Aguiar, Maria Cássia Ferreira, and Grossmann, Soraya de Mattos Camargo

Subjects
SALIVARY gland tumors, CROSS-sectional method, FISHER exact test, CHI-squared test, DESCRIPTIVE statistics, MEDICAL practice, DATA analysis software, SYMPTOMS
Abstract

Objective: To describe the frequency, clinical, and demographic features of minor salivary gland tumors and possible associated factors. Materials and methods: A cross‐sectional study was conducted. Clinical and demographic data were collected from biopsy records of two oral pathology services. Chi‐square test, Fisher's exact test, and descriptive statistical analysis were performed. Results: A total of 480 (0.89%) minor salivary gland tumors were retrieved, 272 (56.7%) benign and 147 (30.7%) malignant. Sixty‐one (12.6%) had no subtype specification. Most patients were women (307/64.0%), in sixth decade of life (80/16.7%), with a mean age of 45.32 years. Palate was the most common site (336/70.1%). Pleomorphic adenoma (PA; 245/51.1%), mucoepidermoid carcinoma (MEC; 70/14.6%), and adenoid cystic carcinoma (ACC; 43/8.9%) were the most frequent tumors. Symptomatic case, recurrence, and tobacco use were associated with malignancy (p < 0.05). PA and MEC were more frequent in palate (p < 0.05). No association between the three most frequent histological types and gender or age group was observed (p > 0.05). Conclusions: This represents one of the largest exclusive series of minor salivary gland tumors in Brazil and worldwide. PA, MEC, and ACC were the most frequent tumors. Clinical and demographic data are similar from Brazilian studies or from other countries. [ABSTRACT FROM AUTHOR]

Published
2023
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26. An exophytic growth over the alveolar ridge.

Author

da Costa, Adriana Aparecida Silva, Tavares, Thalita Soares, Meirelles, Daniela Pereira, Caldeira, Patrícia Carlos, Barcelos, Natália Santos, de Oliveira, Eduardo Morato, Milagres, Roselaine Moreira Coelho, and de Aguiar, Maria Cássia Ferreira

Published
2023
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28. Effects of tobacco on the DNA of smokers and non-smokers affected by OSCC: systematic review and meta-analysis.

Author

SCHUCH, Lauren Frenzel, VIANA, Karolina Skarlet Silva, DE ARRUDA, José Alcides Almeida, ABREU, Lucas Guimarães, de AGUIAR, Maria Cássia Ferreira, and BERNARDES, Vanessa Fátima

Subjects
NON-smokers, DNA, SQUAMOUS cell carcinoma, SMOKING statistics, DNA adducts, TOBACCO, HEAD & neck cancer
Abstract

Scientific evidence about genetic and molecular changes in oral squamous cell carcinoma (OSCC) among smokers and non-smokers is inconclusive. This systematic review and meta-analysis assessed the effects of tobacco on the DNA of individuals with OSCC based on protein mutations. Electronic searches were conducted on PubMed, Ovid, Web of Science, and Scopus to identify observational studies published up to January/2022. The Joanna Briggs Institute tool was used for the critical appraisal of studies. The certainty of the evidence was evaluated. Twenty-three studies assessing 4,060 individuals (2,967 smokers vs. 1,093 non-smokers) were included in this review. Fifteen groups of proteins/genes were investigated. Analysis of the quality of articles revealed low risk of bias in most studies. The certainty of the evidence was very low. The meta-analysis confirmed no significant difference between smokers and non-smokers with respect to damage to GSTM1 (OR: 0.60; 95%CI: 0.30-1.18), GSTT1 (OR: 1.18; 95%CI:0.49-2.83), hydrolase proteins (Ku70 and Ku80) (OR: 0.74; 95%CI: 0.18-3.05), and transferase proteins (GSTM1, GSTT1, GSTM3) (OR: 0.74; 95%CI: 0.47-1.18). Most of the studies included showed that smokers are more likely to exhibit genetic instability. However, the meta-analysis revealed that smokers do not necessarily have more genetic alterations in the DNA than non-smokers. [ABSTRACT FROM AUTHOR]

Published
2023
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40. METASTATIC ADENOCARCINOMA OF THE JAW

Author

da COSTA, Adriana Aparecida Silva, de SOUZA, Raquel Helena Junia, BARCELOS, Natália Santos, TAVARES, Thalita Soares, MEIRELLES, Daniela Pereira, de AGUIAR, Maria Cássia Ferreira, and CALDEIRA, Patrícia Carlos

Published
2023
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45. Glandular odontogenic cysts: A collaborative investigation of 22 cases and proteins related to invasiveness.

Author

da Silva, Karine Duarte, Neutzling Gomes, Ana Paula, Balbinot, Karolyny Martins, Sena, Yasmim Rodrigues, Mosconi, Carla, de Mendonça, Elismauro Franscisco, Chaves Tarquinio, Sandra Beatriz, de Melo Alves Junior, Sérgio, de Jesus Viana Pinheiro, João, and de Aguiar, Maria Cássia Ferreira

Subjects
ODONTOGENIC cysts, CANCER invasiveness, DESMOID tumors, IMMUNOHISTOCHEMISTRY, HISTOPATHOLOGY, PROTEIN expression
Abstract

Background: A glandular odontogenic cyst (GOC) has an intriguing, aggressive behaviour whose mechanisms have not yet been clarified. Objective: To conduct a collaborative cross‐sectional study on the clinical, demographic, microscopic and immunohistochemical characteristics of GOCs, emphasizing the histopathological characteristics and expression of proteins related to invasiveness. Methods: Twenty‐two cases of GOC from three oral and maxillofacial pathology services in Brazil were selected from 1988 to 2018. Clinical and demographic data were collected. Histopathological features were evaluated in detail. Sixteen cases of GOC were also submitted to immunohistochemistry to detect MT1‐MMP, TKS4, TKS5 and cortactin, the key regulators of invadopodia formation. Results: Glandular odontogenic cysts were primarily seen in men over 40 years of age, in the posterior mandible and the anterior maxilla as a unilocular, radiolucent lesion. All cases presented hobnail cells, clear cells and variable thickness of the lining epithelium, 3 of the 10 key histopathological parameters to be evaluated in GOCs. Immunohistochemistry revealed a greater expression of the studied proteins in the GOCs than in the controls (p < 0.0001). Conclusion: Overexpression of proteins that regulate cell invasiveness was identified, and the present study's findings suggest that invadopodia activity is a possible mechanism used by GOCs to promote local invasion, which could partly explain its intriguing biological behaviour. [ABSTRACT FROM AUTHOR]

Published
2022
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48. A Brazilian multicentre study of 2,497 isolated cases of odontogenic keratocysts

Author

Schuch, Lauren Frenzel, primary, de Arruda, José Alcides Almeida, additional, Mosconi, Carla, additional, Kirschnick, Laura Borges, additional, Pinho, Rodrigo Finger de Carvalho, additional, Viveiros, Stephanie Kenig, additional, Abreu, Lucas Guimarães, additional, Amaral‐Silva, Gleyson Kleber, additional, da Silva, Leorik Pereira, additional, Martins‐Chaves, Roberta Rayra, additional, Vasconcelos, Ana Carolina Uchoa, additional, Gomes, Ana Paula Neutzling, additional, Rivero, Elena Riet Correa, additional, Martins, Manoela Domingues, additional, Rados, Pantelis Varvaki, additional, de Almeida, Oslei Paes, additional, de Andrade, Bruno Augusto Benevenuto, additional, Romañach, Mário José, additional, Agostini, Michelle, additional, Mendonça, Elismauro Francisco, additional, Pontes, Hélder Antonio Rebelo, additional, Souza, Lélia Batista, additional, Fonseca, Felipe Paiva, additional, de Aguiar, Maria Cássia Ferreira, additional, de Sousa, Suzana Cantanhede Orsini Machado, additional, and Mesquita, Ricardo Alves, additional

Published
2020
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