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3 results on '"D.A. Reinke"'

1. Prostaglandin-Forming Cyclooxygenase in Renal Medulla of Spontaneously Hypertensive Rats during Development

Author

V.G. Stygles, D.A. Reinke, J.B. Hook, and W.L. Smith

Subjects
medicine.medical_specialty, Antigenicity, Fluorescent Antibody Technique, Prostaglandin, Immunofluorescence, chemistry.chemical_compound, Internal medicine, medicine, Renal medulla, Animals, cardiovascular diseases, chemistry.chemical_classification, Kidney Medulla, medicine.diagnostic_test, biology, Rats, Inbred Strains, In vitro, Rats, Wistar kyoto, Enzyme, medicine.anatomical_structure, Endocrinology, Animals, Newborn, chemistry, Prostaglandin-Endoperoxide Synthases, Hypertension, Pediatrics, Perinatology and Child Health, Prostaglandins, biology.protein, Cyclooxygenase, Developmental Biology
Abstract

Increased activity of prostaglandin synthetase in spontaneously hypertensive rats (SHR) during development has previously been reported. The investigations reported herein utilized an immunofluorescent technique to qualitatively assess the activity of the first enzyme in the PGE2 biosynthetic pathway, the prostaglandin-forming cyclooxygenase (PG-C), in SHR kidneys during development. PG-C antigenicity increased from 4 to 15 weeks in both SHRs and Wistar Kyoto normotensive rats. However, in agreement with our previous in vitro data no difference in PG-C was observed between strains at any age.

Published
1978

2. Contents, Vol. 33, 1978

Author

W.L. Smith, Marcel U.K. Mgbodile, T. Meloni, D.A. Reinke, Roland Leeson, Mallet E, R. Vaillant, Edward L. Keller, I.E. Hopkin, C. Gautier, William J. Krause, Flora De Biasi, F Cantarutti, Rajagopalan C. Nair, Giorgio Stramentinoli, Laura Chiozza, L.H.J. Ramaekers, Henry L. Patthey, Jean-Paul Basuyau, E. Brachet, Harry Cutts, Mario Rondinelli, J.J. Roord, Willgerodt H, Henrietta Man-Hing Ip, Brunelle P, Sergio O. Saia, Firmino F. Rubaltelli, A. Masala, Salil K. Das, Claude Fessard, G. Delitala, R. Corti, William Berman, V.G. Stygles, R.A. Saunders, Bührdel P, Michael A. Heymann, J.B. Hook, Robert C. Goodlin, Giuliano Enzi, Abraham M. Rudolph, H. Theile, Mario Bondio, Anthony D Milner, P. Metzger, and Anne-Marie Devaux

Subjects
Pediatrics, Perinatology and Child Health, Developmental Biology
Published
1978

3. Increased blood pressure in the SHR is not related to a deficit in renomedullary PGE2

Author

D.A. Reinke, D. E. Rickert, Jerry B. Hook, and V.G. Stygles

Subjects
medicine.medical_specialty, Medullary cavity, Blood Pressure, Cellular and Molecular Neuroscience, Internal medicine, medicine, Renal medulla, Animals, cardiovascular diseases, Prostaglandin E2, Molecular Biology, Pharmacology, Kidney Medulla, business.industry, Prostaglandins E, Prostaglandin synthesis, Age Factors, Cell Biology, Rats, Endocrinology, medicine.anatomical_structure, Blood pressure, Hypertension, cardiovascular system, Molecular Medicine, business, medicine.drug
Abstract

Synthesis of prostaglandin E2 by renal medulla from SHR and WKY rats was compared during early postnatal development. Although arterial blood pressure was significantly higher in SHR as early as 6 weeks of age, no difference in renal medullary prostaglandin synthesis was observed.

Published
1978

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