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Coronary artery disease otherwise named as Coronary heart disease. Coronary Artery Disease means narrowing of the coronary arteries. This narrowing causes reduction of blood flow to the heart muscle by buildup of plaque in the arteries of heart. A common symptom of Coronary artery disease is chest pain or chest discomfort which can travel to the shoulder, arm, back, neck or jaws. Other symptoms may include Shortness of breath, palpitations and even fatigue. Majorly antiplatelets are given in the treatment of CAD and followed by angioplasty for the clearing of plaques in the coronary artery. Collected a sample size of 200 patients, among them 126 are males and 74 are females. Patient with age group of 51-60 are more prone to CAD in both males and females. Chest pain is majorly seen in males compared to females. Chest pain, Sweating and shortness of breath is seen in both males and females and the number of male patients are more when compared to females. Patients with only shortness of breath are less when compared to other chief complaints. Social history includes Smokers are 26 (47.2%), alcoholic are 48 (57.14%).. Among all these patients the length of hospital stay of patients treated with combination of aspirin and clopidogrel is less when compared with ticagrelor, aspirin, clopidogrel.Based on the follow up observations we may consider that combination of antiplatelet therapy is effective in CAD patients undergone with percutaneous transluminal coronary angioplasty.

Purpose Major burden of cardiovascular disease (CVD) mortality around the globe is due to atherosclerosis and its complications. Hence its early detection and management with easily accessible and non-invasive methods is valuable. Epicardial adipose tissue thickness (EAT) through transthoracic two dimensional (2D) echocardiography determines highly active intrathoracic visceral adipose tissue burden which increases atherosclerosis. 1 We did this study to find the utility of EAT in predicting coronary artery disease (CAD) burden and compare with carotid intima media thickness (CIMT) which is an established surrogate marker of atherosclerosis. Methods In this cross-sectional comparative study, we measured EAT by 2D echocardiography and CIMT by B-mode ultrasound in 161 patients, who underwent coronary angiogram (CAG) for various clinical indications. Coronary artery disease was considered significant if more than 70% diameter stenosis is present in any epicardial coronary artery and insignificant if otherwise. Results On coronary aniography (CAG) 65.2% of patients had significant CAD, 24.3% had insignificant disease and 10.5% had normal coronaries. Epicardial adipose tissue was 0.59 ± 0.26 cm in normal coronary artery group, 0.61 ± 0.20 cm in insignificant CAD group and 0.72 ± 0.19 cm in significant CAD group (p Conclusions EAT and CIMT can predict CAD burden in a robust way. EAT may emerge as an exquisite bedside tool to predict atherosclerotic burden and guide to implement preventive therapy for cardiovascular disease.