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1. High deuteron and neutron yields from the interaction of a petawatt laser with a cryogenic deuterium jet

Author: X. Jiao, C. B. Curry, M. Gauthier, H.-G. J. Chou, F. Fiuza, J. B. Kim, D. D. Phan, E. McCary, E. C. Galtier, G. M. Dyer, B. K. Ofori-Okai, L. Labun, O. Z. Labun, C. Schoenwaelder, R. Roycroft, G. Tiwari, G. D. Glenn, F. Treffert, S. H. Glenzer, and B. M. Hegelich
Subjects: laser-driven neutron source, high-flux neutron source, rapid neutron capture process, laboratory astro-nuclear physics experiment, laser-driven fusion, laser-driven ion source, Physics, QC1-999
Abstract: A compact high-flux, short-pulse neutron source would have applications from nuclear astrophysics to cancer therapy. Laser-driven neutron sources can achieve fluxes much higher than spallation and reactor neutron sources by reducing the volume and time in which the neutron-producing reactions occur by orders of magnitude. We report progress towards an efficient laser-driven neutron source in experiments with a cryogenic deuterium jet on the Texas Petawatt laser. Neutrons were produced both by laser-accelerated multi-MeV deuterons colliding with Be and mixed metallic catchers and by d (d,n)3He fusion reactions within the jet. We observed deuteron yields of 1013/shot in quasi-Maxwellian distributions carrying ∼8−10% of the input laser energy. We obtained neutron yields greater than 1010/shot and found indications of a deuteron-deuteron fusion neutron source with high peak flux (>1022 cm−2 s−1). The estimated fusion neutron yield in our experiment is one order of magnitude higher than any previous laser-induced dd fusion reaction. Though many technical challenges will have to be overcome to convert this proof-of-principle experiment into a consistent ultra-high flux neutron source, the neutron fluxes achieved here suggest laser-driven neutron sources can support laboratory study of the rapid neutron-capture process, which is otherwise thought to occur only in astrophysical sites such as core-collapse supernova, and binary neutron star mergers.
Published: 2023
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2. Seasonal variation of multiple-muon cosmic ray air showers observed in the NOvA detector on the surface

Author: Ch. Kullenberg, J. K. Nelson, A. C. Booth, J. Franc, S. Calvez, V. Matveev, A. Back, R. Petti, Jordan Ott, I. Kakorin, A. Norman, Maury Goodman, L. Cremonesi, P. Ding, W. Mu, Petr Vokac, Jeremy Wolcott, N. Solomey, V. Bhatnagar, Yue Zhang, T. Miao, B. Ramson, A. Rafique, C. Kuruppu, M. Kubu, Gregory J Pawloski, J. Smolik, D. Naples, S. C. Tognini, Stanley G. Wojcicki, T. Olson, F. Hakl, L. Asquith, F. Gao, C. Sweeney, Gavin Davies, R. Keloth, R. Zwaska, M. A. Acero, Pierre Baldi, Andrew J. Sutton, J. Hartnell, P. Lasorak, P. Filip, R. Bowles, T. E. Coan, Milos Lokajicek, Y. Yu, Z. Djurcic, Nikolay Anfimov, O. Samoylov, A. Antoshkin, S. R. Mishra, A. Mislivec, F. Jediny, V. Ryabov, E. Arrieta-Diaz, B. Mayes, A. Sousa, Marvin L Marshak, Juergen Thomas, O.L. Klimov, A. Giri, L. Aliaga, S. Magill, S. Swain, M. Martinez-Casales, D. D. Phan, A. Butkevich, T. Vrba, J. Hewes, B. Jargowsky, B. C. Choudhary, M. Muether, C. Bromberg, B. Guo, S. Bashar, Ken Heller, P. F. Derwent, Cari L. Johnson, R. Nichol, K. Yonehara, Jianbei Liu, D. Doyle, J. Blair, W. A. Mann, R. Hatcher, R. Ehrlich, A. Aurisano, Matthew L Strait, E. C. Dukes, M. Wallbank, J. C.C. Porter, B. A. Bambah, M. Judah, B. Bhuyan, M. C. Sanchez, J. M. Paley, T. Thakore, W. Wu, G. J. Feldman, A. Lister, H. Duyang, O. Petrova, Ajay Kumar, M. Baird, J. Tripathi, D. Whittington, H. Meyer, T. Nosek, J. Zalesak, K. Bays, M. Colo, P. Rojas, A. Sheshukov, M. Dolce, R. Mohanta, E. Smith, A. Hall, D. Kalra, V. Singh, Reddy Pratap Gandrajula, Alec Habig, S. Edayath, M. Wetstein, R. Kralik, R. Bernstein, P. Snopok, H. R. Gallagher, Yong Xiao, A. Moren, R. Plunkett, Vlastimil Kus, Z. Vallari, A. Himmel, M. Rajaoalisoa, L. Mualem, E. Catano-Mur, A. Norrick, K. Soustruznik, J. Vasel, S. Zadorozhnyy, L. Kolupaeva, V. Grichine, M. Elkins, T. J. Carroll, Alexander Olshevskiy, P. Shanahan, J. Jarosz, L. Suter, N. Balashov, S. Yu, M. Manrique Plata, Anna L Morozova, E. Niner, Karol Lang, H. Oh, M. J. Frank, K. Mulder, T. Lackey, L. W. Koerner, R. B. Patterson, R. B. Thayyullathil, S. Kotelnikov, P. Vahle, Warner A. Miller, J. Lesmeister, V. Raj, A. Christensen, T. K. Warburton, D. A. Wickremasinghe, A. Yallappa Dombara, N. Buchanan, S. Sánchez Falero, D. Dueñas Tonguino, B. Rebel, E. Tiras, R. A. Gomes, Petr Tas, D. M. Kaplan, B. Tapia Oregui, N. Nayak, Jian-Guo Bian, M. Groh, A. Holin, A. Kalitkina, J. Urheim, J. Trokan-Tenorio, Simon Lin, P. Singh, P. Adamson, E. Ewart, C. Backhouse, H. Hausner, M. D. Messier, and Y. Torun
Subjects: Physics, High Energy Physics - Experiment (hep-ex), Muon, Detector, FOS: Physical sciences, Cosmic ray, Astrophysics, Nova (laser), Effective temperature, Surface pressure, Atmospheric temperature, Zenith, High Energy Physics - Experiment
Abstract: We report the rate of cosmic ray air showers with multiplicities exceeding 15 muon tracks recorded in the NOvA Far Detector between May 2016 and May 2018. The detector is located on the surface under an overburden of 3.6 meters water equivalent. We observe a seasonal dependence in the rate of multiple-muon showers, which varies in magnitude with multiplicity and zenith angle. During this period, the effective atmospheric temperature and surface pressure ranged between 210 K and 230 K and 940 mbar and 990 mbar, respectively; the shower rates are anticorrelated with the variation in the effective temperature. The variations are about 30% larger for the highest multiplicities than the lowest multiplicities and 20% larger for showers near the horizon than vertical showers.
Published: 2021

3. Search for Active-Sterile Antineutrino Mixing Using Neutral-Current Interactions with the NOvA Experiment

Author: M A, Acero, P, Adamson, L, Aliaga, N, Anfimov, A, Antoshkin, E, Arrieta-Diaz, L, Asquith, A, Aurisano, A, Back, C, Backhouse, M, Baird, N, Balashov, P, Baldi, B A, Bambah, S, Bashar, K, Bays, R, Bernstein, V, Bhatnagar, B, Bhuyan, J, Bian, J, Blair, A C, Booth, R, Bowles, C, Bromberg, N, Buchanan, A, Butkevich, S, Calvez, T J, Carroll, E, Catano-Mur, B C, Choudhary, A, Christensen, T E, Coan, M, Colo, L, Cremonesi, G S, Davies, P F, Derwent, P, Ding, Z, Djurcic, M, Dolce, D, Doyle, D, Dueñas Tonguino, E C, Dukes, H, Duyang, S, Edayath, R, Ehrlich, M, Elkins, E, Ewart, G J, Feldman, P, Filip, J, Franc, M J, Frank, H R, Gallagher, R, Gandrajula, F, Gao, A, Giri, R A, Gomes, M C, Goodman, V, Grichine, M, Groh, R, Group, B, Guo, A, Habig, F, Hakl, A, Hall, J, Hartnell, R, Hatcher, H, Hausner, K, Heller, J, Hewes, A, Himmel, A, Holin, J, Huang, B, Jargowsky, J, Jarosz, F, Jediny, C, Johnson, M, Judah, I, Kakorin, D, Kalra, A, Kalitkina, D M, Kaplan, R, Keloth, O, Klimov, L W, Koerner, L, Kolupaeva, S, Kotelnikov, R, Kralik, Ch, Kullenberg, M, Kubu, A, Kumar, C D, Kuruppu, V, Kus, T, Lackey, P, Lasorak, K, Lang, J, Lesmeister, S, Lin, A, Lister, J, Liu, M, Lokajicek, S, Magill, M, Manrique Plata, W A, Mann, M L, Marshak, M, Martinez-Casales, V, Matveev, B, Mayes, D P, Méndez, M D, Messier, H, Meyer, T, Miao, W H, Miller, S R, Mishra, A, Mislivec, R, Mohanta, A, Moren, A, Morozova, W, Mu, L, Mualem, M, Muether, K, Mulder, D, Naples, N, Nayak, J K, Nelson, R, Nichol, E, Niner, A, Norman, A, Norrick, T, Nosek, H, Oh, A, Olshevskiy, T, Olson, J, Ott, J, Paley, R B, Patterson, G, Pawloski, O, Petrova, R, Petti, D D, Phan, R K, Plunkett, J C C, Porter, A, Rafique, V, Raj, M, Rajaoalisoa, B, Ramson, B, Rebel, P, Rojas, V, Ryabov, O, Samoylov, M C, Sanchez, S, Sánchez Falero, P, Shanahan, A, Sheshukov, P, Singh, V, Singh, E, Smith, J, Smolik, P, Snopok, N, Solomey, A, Sousa, K, Soustruznik, M, Strait, L, Suter, A, Sutton, S, Swain, C, Sweeney, B, Tapia Oregui, P, Tas, T, Thakore, R B, Thayyullathil, J, Thomas, E, Tiras, J, Tripathi, J, Trokan-Tenorio, A, Tsaris, Y, Torun, J, Urheim, P, Vahle, Z, Vallari, J, Vasel, P, Vokac, T, Vrba, M, Wallbank, T K, Warburton, M, Wetstein, D, Whittington, D A, Wickremasinghe, S G, Wojcicki, J, Wolcott, W, Wu, Y, Xiao, A, Yallappa Dombara, K, Yonehara, S, Yu, Y, Yu, S, Zadorozhnyy, J, Zalesak, Y, Zhang, and R, Zwaska
Subjects: Physics, Particle physics, Neutral current, Oscillation, FOS: Physical sciences, General Physics and Astronomy, Nova (laser), NuMI, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), High Energy Physics::Experiment, Fermilab, Beam (structure), Mixing (physics), Bar (unit)
Abstract: This Letter reports results from the first long-baseline search for sterile antineutrinos mixing in an accelerator-based antineutrino-dominated beam. The rate of neutral-current interactions in the two NOvA detectors, at distances of 1 km and 810 km from the beam source, is analyzed using an exposure of $12.51\times10^{20}$ protons-on-target from the NuMI beam at Fermilab running in antineutrino mode. A total of $121$ of neutral-current candidates are observed at the Far Detector, compared to a prediction of $122\pm11$(stat.)$\pm15$(syst.) assuming mixing between three active flavors. No evidence for $\bar{\nu}_{\mu}\rightarrow\bar{\nu}_{s}$ oscillation is observed. Interpreting this result within a 3+1 model, constraints are placed on the mixing angles ${\theta}_{24} < 25^{\circ}$ and ${\theta}_{34} < 32^{\circ}$ at the 90% C.L. for $0.05$eV$^{2} \leq \Delta m^{2}_{41} \leq 0.5$eV$^{2}$, the range of mass splittings that produces no significant oscillations at the Near Detector. These are the first 3+1 confidence limits set using long-baseline accelerator antineutrinos., Comment: 8 pages, 4 figures
Published: 2021

4. Improved Constraints on Sterile Neutrino Mixing from Disappearance Searches in the MINOS, MINOS+ , Daya Bay, and Bugey-3 Experiments

Author: J. L. Sun, E. T. Worcester, F. Z. Qi, Jingyuan Guo, X. H. Guo, M. Dvořák, C. H. Wang, Feiyang Zhang, Richard Rosero, Jen-Chieh Peng, X. L. Ji, J. Park, J. H. C. Lee, J. P. Gallo, Miao He, A. E. Kreymer, S. V. Cao, J. Dove, Yuda Zeng, P. Lucas, Marvin L Marshak, Shanfeng Li, Chun S. J. Pun, Zhuojun Hu, D. C. Jones, Li Zhou, Christopher L. Marshall, J. F. Chang, A. B. Balantekin, Diru Wu, N. Poonthottathil, Yunzhe Liu, D. M. Xia, Shaomin Chen, Jun Cao, R. Chen, N. Graf, Y. Y. Ding, S. Hans, C. Lu, J. L. Xu, Rakesh Sharma, R. W. Hackenburg, S. R. Hahn, Haifeng Yao, S. Childress, S. H. Kettell, X. B. Ma, A. Aurisano, Honghan Gong, Maxim Gonchar, Xinglong Li, Z. Wang, S. F. Li, R. A. Johnson, H. H. Zhang, Jiawen Zhang, Fengpeng An, Yuhang Guo, Alexander Olshevskiy, Siew Cheng Wong, H. R. Band, Guey-Lin Lin, Jonathan S. Lu, Dmitry V. Naumov, Lin Yang, J. K. Nelson, D. E. Jaffe, H. Liang, Yixue Chen, G. B. Mills, Z. Y. Yu, Z. K. Cheng, K. Whisnant, J. J. Ling, Karol Lang, Z. P. Zhang, J. R. Meier, Jinmei Liu, Simon Blyth, J. Cheng, M. Kordosky, Jing Zhao, S. Li, X. Y. Ma, R. Mehdiyev, S. J. Patton, J. Schneps, Andrew Blake, M. Z. Wang, Ming Chung Chu, Zhangquan Xie, H. L. Zhuang, Michael Kramer, I. Anghel, A. Timmons, C. Morales Reveco, F. L. Wu, Y. X. Zhang, M. M. Pfützner, R. K. Plunkett, Yufeng Li, K. L. Jen, Ž. Pavlović, W. J. Wu, Vit Vorobel, R. D. McKeown, Wei Li, Artem Chukanov, N. Dash, Yue Meng, P. Sail, M. V. Diwan, Zhiyong Zhang, B. Roskovec, John Evans, X. Q. Li, M. Qi, M. Bishai, Tadeas Dohnal, Hongzhao Yu, Jing Wang, A. Schreckenberger, Nasir Shaheed, Hanxiong Huang, Z. B. Li, Y. Z. Yang, L. Kang, Qingmin Zhang, J. K. C. Leung, Gregory J Pawloski, R. T. Lei, Hongliang Li, P. Gouffon, X. Qiu, M. Ye, W. Wang, B. Z. Hu, N. Y. Wang, M. A. Thomson, D. Naples, B. Viren, Jianrun Hu, Stanley G. Wojcicki, L. Guo, Zhijian Zhang, Jiachen Li, J. O'Connor, Alec Habig, Y. B. Hsiung, Chao Zhang, K. Grzelak, J. J. Cherwinka, Xiaolu Ji, Liangjian Wen, D. D. Phan, Guofu Cao, L. H. Wei, K. Treskov, N. Raper, Jinjuan Ren, Q. J. Li, W. A. Mann, R. Hatcher, R. A. Gomes, Jim Napolitano, N. Tagg, A. Radovic, Qinglong Wu, G.D. Barr, Junwei Huang, Kam Biu Luk, G. J. Feldman, Yinhong Zhang, Z. Guo, Tian Xue, A. Holin, Juergen Thomas, Y. K. Heng, K. T. McDonald, J. Todd, Yanhui Liu, A. C. Weber, A. Perch, X. C. Ruan, Xin Qian, Guanghua Gong, Joao A B Coelho, Chi Lin, Juan Pedro Ochoa-Ricoux, L. Mora Lepin, A. Higuera, X. T. Huang, C. G. Yang, H. R. Pan, Zhi-zhong Xing, S. De Rijck, C. E. Tull, D. Torretta, J. Lee, H. Y. Wei, H. L. H. Wong, J. Hartnell, H. S. Chen, T. J. Carroll, P. Adamson, Y. K. Hor, Jianglai Liu, L. W. Koerner, X. Wang, Haoqi Lu, Y. F. Wang, W. Flanagan, T. Tmej, S. Kohn, S. Germani, Warner A. Miller, R. Toner, E. Naumova, D. A. Dwyer, T. J. Langford, A. Sousa, Yuman Wang, S. Zeng, W. Q. Gu, H. M. Steiner, P. Vahle, Y. Q. Ma, F. S. Deng, Bing-Lin Young, B. R. Littlejohn, Yaoyu Zhang, Y. B. Huang, Patrick Huber, Y. H. Chang, X. T. Zhang, Shengxin Lin, C. M. Castromonte, T. Hu, D. A. Martinez Caicedo, Minfang Yeh, Yongzhu Chen, Baobiao Yue, F. Li, R. G. Wang, W. H. Tse, R. J. Nichol, N. Mayer, Liang Zhan, K. M. Heeger, Christopher G. White, S. C. Tognini, Rupert Leitner, D. Dolzhikov, T. Xu, J. M. Link, J. P. Cummings, mrow, Leigh H. Whitehead, M. Y. Gabrielyan, L. S. Littenberg, M. C. Sanchez, R. B. Pahlka, and Z. M. Wang
Subjects: Physics, Particle physics, Sterile neutrino, Muon, General Physics and Astronomy, 01 natural sciences, MiniBooNE, MINOS, 0103 physical sciences, Muon neutrino, Neutron, 010306 general physics, Electron neutrino, Mixing (physics)
Abstract: Searches for electron antineutrino, muon neutrino, and muon antineutrino disappearance driven by sterile neutrino mixing have been carried out by the Daya Bay and MINOS+ collaborations. This Letter presents the combined results of these searches, along with exclusion results from the Bugey-3 reactor experiment, framed in a minimally extended four-neutrino scenario. Significantly improved constraints on the θ_{μe} mixing angle are derived that constitute the most constraining limits to date over five orders of magnitude in the mass-squared splitting Δm_{41}^{2}, excluding the 90% C.L. sterile-neutrino parameter space allowed by the LSND and MiniBooNE observations at 90% CL_{s} for Δm_{41}^{2}
Published: 2020
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5. Precision Constraints for Three-Flavor Neutrino Oscillations from the Full MINOS+ and MINOS Dataset

Author: G. J. Feldman, A. Holin, R. A. Gomes, S. C. Tognini, M. A. Thomson, D. Naples, Stanley G. Wojcicki, A. Aurisano, J. O'Connor, J. K. Nelson, R. Toner, A. Schreckenberger, L. W. Koerner, T. J. Carroll, Gregory J Pawloski, A. Sousa, W. Flanagan, J. Schneps, P. Vahle, R. Mehdiyev, P. Adamson, C. M. Castromonte, mrow, M. M. Pfützner, R. Hatcher, S. De Rijck, M. Kordosky, I. Anghel, Leigh H. Whitehead, M. Y. Gabrielyan, R. J. Nichol, N. Mayer, G. B. Mills, M. C. Sanchez, R. B. Pahlka, S. Germani, Andrew Blake, Warner A. Miller, John Evans, X. Qiu, P. Lucas, R. K. Plunkett, A. Timmons, J. R. Meier, S. R. Hahn, A. Perch, P. Sail, A. E. Kreymer, Marvin L Marshak, Ž Pavlović, J. Todd, P. Gouffon, R. Chen, D. Torretta, Rakesh Sharma, S. Childress, S. V. Cao, J. Hartnell, Joao A B Coelho, N. Graf, N. Tagg, G.D. Barr, Junwei Huang, Juergen Thomas, N. Poonthottathil, K. Grzelak, A. C. Weber, D. D. Phan, W. A. Mann, Alec Habig, Karol Lang, and A. Radovic
Subjects: Physics, Particle physics, General Physics and Astronomy, FOS: Physical sciences, 01 natural sciences, Neutrino Oscillations, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), Neutrino detector, MINOS, Neutrino Detectors, 0103 physical sciences, Neutrino Oscillations, Neutrino Detectors, Neutrino, 010306 general physics, Neutrino oscillation
Abstract: We report the final measurement of the neutrino oscillation parameters $\Delta m^2_{32}$ and $\sin^2\theta_{23}$ using all data from the MINOS and MINOS+ experiments. These data were collected using a total exposure of $23.76 \times 10^{20}$ protons on target producing $\nu_{mu}$ and $\overline{\nu_\mu}$ beams and 60.75 kt$\cdot$yr exposure to atmospheric neutrinos. The measurement of the disappearance of $\nu_{\mu}$ and the appearance of $\nu_e$ events between the Near and Far detectors yields $|\Delta m^2_{32}|=2.40^{+0.08}_{-0.09}~(2.45^{+0.07}_{-0.08}) \times 10^{-3}$ eV$^2$ and $\sin^2\theta_{23} = 0.43^{+0.20}_{-0.04} ~(0.42^{+0.07}_{-0.03})$ at 68% C.L. for Normal (Inverted) Hierarchy., Comment: 6 pages, 4 figures, 3 tables
Published: 2020
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6. First measurement of neutrino oscillation parameters using neutrinos and antineutrinos by NOvA

Author: R. Murphy, C. Bromberg, Borun D. Chowdhury, R. B. Patterson, Anjan K. Giri, H. Duyang, S. Zadorozhnyy, D. Naples, M. Campbell, Stanley G. Wojcicki, W. Flanagan, A. Cedeno, N. Yadav, A. Holin, V Grichine, R. H. Bernstein, S. Edayath, S. Yu, M. Martinez-Casales, E. C. Dukes, Katsuya Yonehara, T. E. Coan, Cari L. Johnson, P. Ding, I. Kakorin, P. Shanahan, D. Doyle, I. Kourbanis, R. Ehrlich, E. Catano-Mur, J. Tripathi, A. Sheshukov, S. Altakarli, T. Miao, T. Olson, A. Aurisano, B. Tapia Oregui, N. Nayak, F. Gao, V. A. Matveev, Bo Wang, A. Radovic, S. R. Mishra, Bindu A. Bambah, R. Hatcher, F. Psihas, R. A. Rameika, Ihn Sik Seong, B. Bhuyan, Brajesh C Choudhary, D. D. Phan, E. Smith, J. K. Nelson, G. Nikseresht, D. P. Méndez, Pavel Snopok, J. Lozier, B. Zamorano, K. Mulder, Petr Tas, L. Cremonesi, V. A. Ryabov, W. A. Mann, J. Cooper, K. Bays, V. Allakhverdian, Rukmani Mohanta, Andrew Norman, Matthew L Strait, W. H. Miller, P. Singh, J. M. Paley, E. Song, Simon J. Bending, H. Meyer, M. C. Sanchez, O. Petrova, N. Balashov, A. Yallappa Dombara, Vipin Bhatnagar, V. Raj, T. K. Warburton, T. Nosek, J. Hartnell, J. Urheim, P. Vahle, L. Vinton, H. R. Gallagher, A. Hatzikoutelis, Vlastimil Kus, Ch Kulenberg, M. Judah, A. Back, Junwei Huang, A. Kumar, R. Zwaska, T. Lackey, M. D. Messier, A. E. Kreymer, B. V.K.S. Potukuchi, Simon Lin, J. Zalesak, D. Pershey, M. Baird, Petr Vokac, Jeremy Wolcott, Jianming Bian, J. Hewes, C. Backhouse, Alexander Olshevskiy, D. Torbunov, Marvin L Marshak, Stanislav Luchuk, A. Booth, Gregory J Pawloski, J. A. Musser, N. Buchanan, S. Sánchez Falero, M. Wetstein, Juergen Thomas, B. Guo, P. Adamson, S. Bashar, Ken Heller, D. Kalra, C. Principato, Nikolay Anfimov, M. R. While, O. Klimov, M. Groh, A. Moren, C. Kuruppu, B. Rebel, K. Soustruznik, Karol Lang, F. Hakl, A. Mislivec, L. W. Koerner, L. Suter, M. Elkins, T. J. Carroll, Pierre Baldi, E. Tiras, R. Gandrajula, T. Vrba, Yagmur Torun, R. B. Thayyullathil, Andrew J. Sutton, F. Jediny, Anatoly Butkevich, J. Blair, P. Filip, M. Muether, M. Wallbank, S Kotelnikov, R. A. Gomes, A. Antoshkin, S. Magill, G. J. Feldman, R. Petti, D. Whittington, M. J. Frank, J. Vasel, R. K. Plunkett, K. Maan, Maury Goodman, V. Singh, L. Kolupaeva, P. F. Derwent, L. Corwin, A. Tsaris, T. Blackburn, S. L. Mufson, B. Howard, S. Calvez, P. Rojas, T. Alion, A. Sousa, Z. Djurcic, R. L. Talaga, Daniel M. Kaplan, J. Hylen, S. Germani, M. Colo, L. Aliaga, Alec Habig, Gavin Davies, R. J. Nichol, M. A. Acero, A. Himmel, P. Bour, L. Mualem, Milos Lokajicek, E. Niner, O. Samoylov, J. Smolik, S. Childress, N. Solomey, and R. Keloth
Subjects: Physics, Particle physics, Neutrino oscillations, High Energy Physics::Phenomenology, FOS: Physical sciences, General Physics and Astronomy, Nova (laser), 01 natural sciences, NuMI, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), 0103 physical sciences, High Energy Physics::Experiment, Fermilab, Neutrino, 010306 general physics, Neutrino oscillation, Mass hierarchy, QC
Abstract: The NOvA experiment has made a $4.4\sigma$-significant observation of $\bar\nu_{e}$ appearance in a 2 GeV $\bar\nu_{\mu}$ beam at a distance of 810 km. Using $12.33\times10^{20}$ protons on target delivered to the Fermilab NuMI neutrino beamline, the experiment recorded 27 $\bar\nu_{\mu} \rightarrow \bar\nu_{e}$ candidates with a background of 10.3 and 102 $\bar\nu_{\mu} \rightarrow \bar\nu_{\mu}$ candidates. This new antineutrino data is combined with neutrino data to measure the oscillation parameters $|\Delta m^2_{32}| = 2.48^{+0.11}_{-0.06}\times10^{-3}$ eV$^2/c^4$, $\sin^2 \theta_{23} = 0.56^{+0.04}_{-0.03}$ in the normal neutrino mass hierarchy and upper octant and excludes most values near $\delta_{\rm CP}=\pi/2$ for the inverted mass hierarchy by more than 3$\sigma$. The data favor the normal neutrino mass hierarchy by 1.9$\sigma$ and $\theta_{23}$ values in the upper octant by 1.6$\sigma$., Comment: 8 pages, 3 figures. Supplementary material attached (6 figures). To view attachments, please download and extract the gzipped tar source file listed under "Other formats". Fixed supplementary material to include just the compiled pdf not the Latex Source
Published: 2019

7. Search for sterile neutrinos in MINOS and MINOS+ using a two-detector fit

Author: A. Radovic, Karol Lang, S. C. Tognini, T. J. Carroll, Harvey B Newman, S. Germani, X. Tian, A. V. Devan, A. Holin, G. M. Irwin, M. M. Medeiros, G. J. Feldman, Joao A B Coelho, M. V. Diwan, D. Cronin-Hennessy, S. Phan-Budd, A. Sousa, P. Gouffon, R. L. Talaga, M. Kordosky, Andrew Blake, L. Corwin, Leigh H. Whitehead, B. Viren, N. E. Devenish, A. Timmons, M. Y. Gabrielyan, P. J. Litchfield, S. V. Cao, A. E. Kreymer, P. Sail, R. Chen, Marvin L Marshak, J. K. De Jong, J. A. Nowak, Rakesh Sharma, J. M. Paley, P. Schreiner, R. B. Patterson, C. D. Moore, M. A. Thomson, D. Naples, Stanley G. Wojcicki, S. R. Mishra, A. C. Weber, J. O'Connor, D. D. Phan, J. J. Evans, N. Tagg, G.D. Barr, Junwei Huang, M. M. Pfützner, W. A. Mann, S. De Rijck, E. Falk, A. Perch, Z. Isvan, L. Mualem, J. Schneps, M. V. Frohne, H. R. Gallagher, J. Hylen, S. Moed Sher, Juergen Thomas, I. Anghel, C. M. Castromonte, S. Childress, N. Poonthottathil, W. H. Miller, J. K. Nelson, G. Tzanakos, Maury Goodman, Alec Habig, D. A. Jensen, G. Koizumi, R. J. Nichol, N. Mayer, T. Kafka, M. D. Messier, Gregory J Pawloski, C. James, Christopher G. White, L. W. Koerner, M. C. Sanchez, W. Flanagan, R. B. Pahlka, A. Schreckenberger, Carlos Escobar, R. K. Plunkett, J. Todd, X. Qiu, D. Torretta, P. Lucas, J. Hartnell, S. R. Hahn, G. J. Bock, H. A. Rubin, R. Toner, B. Rebel, R. Hatcher, M. Bishai, M. Orchanian, K. Grzelak, J. R. Meier, N. Graf, R. Gran, R. Mehdiyev, P. Vahle, C. L. McGivern, R. A. Gomes, C. Rosenfeld, P. Adamson, D. Bogert, S. M. S. Kasahara, R. Zwaska, R. C. Webb, J. Urheim, A. Aurisano, and J. A. Musser
Subjects: Physics, Sterile neutrino, Particle physics, Physics::Instrumentation and Detectors, Solar neutrino, Astrophysics::High Energy Astrophysical Phenomena, High Energy Physics::Phenomenology, FOS: Physical sciences, General Physics and Astronomy, Solar neutrino problem, 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), Neutrino detector, MINOS, 0103 physical sciences, Measurements of neutrino speed, High Energy Physics::Experiment, Neutrino, 010306 general physics, Neutrino oscillation, QC
Abstract: A search for mixing between active neutrinos and light sterile neutrinos has been performed by looking for muon neutrino disappearance in two detectors at baselines of 1.04 km and 735 km, using a combined MINOS and MINOS+ exposure of $16.36\times10^{20}$ protons-on-target. A simultaneous fit to the charged-current muon neutrino and neutral-current neutrino energy spectra in the two detectors yields no evidence for sterile neutrino mixing using a 3+1 model. The most stringent limit to date is set on the mixing parameter $\sin^2\theta_{24}$ for most values of the sterile neutrino mass-splitting $\Delta m^2_{41} > 10^{-4}$ eV$^2$., Comment: 7 pages, 4 figures, additional analysis details and a data release in the ancillary materials
Published: 2019
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8. Miniature Antenna for IoT Devices Using LoRa Technology

Author: Nguyen-Vu Truong, Fabien Ferrero, V. Q. Tran, V. X Bui, D. D. Phan, Le Huy Trinh, T. Q. K. Nguyen, University of Information Technology, Vietnam National University - HCMC, Laboratoire d'Electronique, Antennes et Télécommunications (LEAT), Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS), Institute of Applied Mechanics and Informatics, IEEE, and CREMANT
Subjects: Frequency band, Computer science, miniature antenna, Mobile antennas, Internet of Things, Geometry, 02 engineering and technology, Information technology, FR-4 board, LoRa, Antenna measurements, Microstrip antenna, Bandwidth, LoRa technology, 0202 electrical engineering, electronic engineering, information engineering, Prototypes, frequency 868.0 MHz, business.industry, microstrip antennas, 020208 electrical & electronic engineering, Bandwidth (signal processing), Electrical engineering, 020206 networking & telecommunications, [SPI.ELEC]Engineering Sciences [physics]/Electromagnetism, electrical small antenna, IoT devices, business, UHF antennas, Uhf antennas
Abstract: International audience; In this paper, the way to design different shapes of miniature antenna for LoRa devices are presented. With dimension of 0.06 lambda x 0.1 lambda the proposed antennas are printed on 34x80x0.8 mm3 FR-4 board . The simulation and experiment results show a good agreement with expectations of the electrical small antennas that operate at 868 MHz frequency band. Moreover, the changeable geometry of the designs while keeping a good performance proves that miniature antennas can be created to be more appealing as logos or figures.
Published: 2017
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9. A search for flavor-changing non-standard neutrino interactions using $ν_{e}$ appearance in MINOS

Author: Christopher G. White, R. J. Nichol, S. Phan-Budd, X. Tian, Stanley G. Wojcicki, A. Sousa, S. V. Cao, D. Cronin-Hennessy, P. Gouffon, B. Viren, M. Bishai, R. A. Gomes, J. M. Paley, R. L. Talaga, J. O'Connor, J. Hylen, G. Tzanakos, M. M. Medeiros, M. C. Goodman, Mcd Sanchez, N. E. Devenish, N. Tagg, G.D. Barr, Junwei Huang, G. Koizumi, Carlos Escobar, M. Orchanian, A. Holin, M. V. Diwan, C. Rosenfeld, C. M. Castromonte, P. Schreiner, N. Mayer, K. Grzelak, J. K. Nelson, Joao A B Coelho, L. H. Whitehead, R. C. Webb, M. V. Frohne, P. Adamson, R. Chen, L. Whitehead, J. K. De Jong, Subhasmita Mishra, C. L. McGivern, A. Schreckenberger, S. Moed Sher, S. M. S. Kasahara, J. Urheim, R. Sharma, R. Toner, P. Vahle, J. A. Nowak, M. Kordosky, S. Childress, T. Kafka, J. C. Thomas, N. Graf, D. A. Jensen, J. Schneps, R. B. Patterson, C. D. Moore, B. Rebel, R. Hatcher, M. D. Messier, X. Qiu, P. Lucas, D. D. Phan, M. Y. Gabrielyan, R. Gran, Andrew Blake, E. Falk, A. Timmons, W. A. Mann, H. R. Gallagher, J. A. Musser, S. C. Tognini, J. J. Evans, M. M. Pfützner, T. J. Carroll, R. Mehdiyev, I. Anghel, W. Flanagan, P. J. Litchfield, S. R. Hahn, Harvey B Newman, R. B. Pahlka, R. K. Plunkett, N. Poonthottathil, A. C. Weber, A. E. Kreymer, L. Corwin, R. Zwaska, S. Germani, Marvin L Marshak, Warner A. Miller, A. Perch, G. M. Irwin, A. V. Devan, G. J. Feldman, P. Sail, J. R. Meier, D. Bogert, S. De Rijck, A. Aurisano, G. J. Bock, J. Todd, M. A. Thomson, D. Torretta, Gregory J Pawloski, L. Mualem, J. Hartnell, C. James, H. A. Rubin, D. Naples, Alec Habig, Z. Isvan, Karol Lang, and A. Radovic
Subjects: Physics, Particle physics, 010308 nuclear & particles physics, Physics::Instrumentation and Detectors, High Energy Physics::Phenomenology, Phase (waves), DETETORES, 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, MINOS, 0103 physical sciences, High Energy Physics::Experiment, Neutrino, 010306 general physics, Flavor, Mixing (physics), QC
Abstract: We report new constraints on flavor-changing non-standard neutrino interactions from the MINOS long-baseline experiment using $\nu_{e}$ and $\bar{\nu}_{e}$ appearance candidate events from predominantly $\nu_{\mu}$ and $\bar{\nu}_{\mu}$ beams. We used a statistical selection algorithm to separate $\nu_{e}$ candidates from background events, enabling an analysis of the combined MINOS neutrino and antineutrino data. We observe no deviations from standard neutrino mixing, and thus place constraints on the non-standard interaction matter effect, $|\varepsilon_{e\tau}|$, and phase, $(\delta_{CP}+\delta_{e\tau})$, using a thirty-bin likelihood fit., Comment: 5 pages, 3 figures v2: References added, caption and probability calculation clarified. Result unchanged
Published: 2017
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10. Measurement of singleπ0production by coherent neutral-currentνFe interactions in the MINOS Near Detector

Author: N. Graf, R. Gran, P. J. Litchfield, M. Bishai, M. Orchanian, K. Grzelak, L. Mualem, S. De Rijck, D. Torretta, M. Kordosky, D. Cronin-Hennessy, R. K. Plunkett, L. Corwin, Carlos Escobar, S. Phan-Budd, Andrew Blake, R. J. Nichol, A. Sousa, M. A. Thomson, J. K. De Jong, A. Perch, J. Hartnell, A. Timmons, H. R. Gallagher, P. Sail, P. Gouffon, S. Moed Sher, N. E. Devenish, A. Holin, R. Zwaska, R. C. Webb, B. Viren, C. Rosenfeld, G. M. Irwin, P. Schreiner, R. Chen, R. Toner, Gregory J Pawloski, M. V. Frohne, P. Adamson, C. M. Castromonte, B. Rebel, M. D. Messier, G. J. Feldman, L. Whitehead, S. Childress, R. L. Talaga, G. Tzanakos, C. James, S. V. Cao, S. M. S. Kasahara, Subhasmita Mishra, C. L. McGivern, G. Koizumi, C. D. Moore, D. A. Jensen, Joao A B Coelho, X. Tian, X. Qiu, A. Schreckenberger, J. Schneps, N. Mayer, D. Cherdack, J. C. Thomas, J. J. Evans, M. M. Pfützner, S. Germani, T. Kafka, A. E. Kreymer, J. K. Nelson, E. Falk, J. Todd, Warner A. Miller, Mcd Sanchez, H. A. Rubin, Z. Isvan, Marvin L Marshak, Christopher G. White, D. Naples, J. M. Paley, A. V. Devan, J. Urheim, R. Sharma, R. B. Pahlka, L. H. Whitehead, D. D. Phan, W. P. Oliver, P. Vahle, M. Y. Gabrielyan, R. A. Gomes, N. Tagg, Alec Habig, Karol Lang, W. A. Mann, W. Flanagan, G.D. Barr, Junwei Huang, M. M. Medeiros, J. A. Musser, R. Hatcher, N. Poonthottathil, P. Lucas, T. J. Carroll, S. C. Tognini, G. J. Bock, Harvey B Newman, R. Mehdiyev, S. R. Hahn, R. B. Patterson, J. R. Meier, A. Radovic, D. Bogert, A. Aurisano, Stanley G. Wojcicki, J. O'Connor, J. Hylen, M. C. Goodman, M. V. Diwan, J. A. Nowak, I. Anghel, and A. C. Weber
Subjects: Physics, Neutral current, 010308 nuclear & particles physics, Scattering, Detector, 01 natural sciences, NuMI, Nuclear physics, MINOS, 0103 physical sciences, Fermilab, Neutrino, 010306 general physics, Coherence (physics)
Abstract: Forward single π^0 production by coherent neutral-current interactions, νA→νAπ^0, is investigated using a 2.8×10^(20) protons-on-target exposure of the MINOS Near Detector. For single-shower topologies, the event distribution in production angle exhibits a clear excess above the estimated background at very forward angles for visible energy in the range 1–8 GeV. Cross sections are obtained for the detector medium comprised of 80% iron and 20% carbon nuclei with ⟨A⟩=48, the highest-⟨A⟩ target used to date in the study of this coherent reaction. The total cross section for coherent neutral-current single π^0 production initiated by the ν_μ flux of the NuMI low-energy beam with mean (mode) E_ν of 4.9 GeV (3.0 GeV), is 77.6±5.0(stat)^(+15.0)_(−16.8)(syst)×10^(−40) cm^2 pernucleus. The results are in good agreement with predictions of the Berger-Sehgal model.
Published: 2016
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11. A search for sterile neutrinos mixing with muon neutrinos in MINOS

Author: R. Hatcher, S. De Rijck, X. Tian, Joao A B Coelho, P. Schreiner, G. M. Irwin, H. A. Rubin, Alec Habig, C. Rosenfeld, G. J. Feldman, M. D. Messier, G. Tzanakos, D. Cronin-Hennessy, E. Falk, N. Graf, P. Adamson, J. R. Meier, Christopher G. White, R. Gran, M. Kordosky, P. Gouffon, M. C. Sanchez, Andrew Blake, T. Kafka, A. C. Weber, Z. Isvan, G. Koizumi, B. Viren, S. M. S. Kasahara, A. Timmons, R. B. Pahlka, L. Mualem, R. Chen, Rakesh Sharma, R. L. Talaga, M. V. Frohne, Gregory J Pawloski, A. E. Kreymer, N. Tagg, S. Childress, L. H. Whitehead, J. K. Nelson, T. J. Carroll, R. C. Webb, C. James, C. M. Castromonte, S. Germani, G.D. Barr, Junwei Huang, Harvey B Newman, A. Holin, M. Bishai, N. Poonthottathil, C. D. Moore, D. Torretta, Marvin L Marshak, Warner A. Miller, R. Mehdiyev, W. Flanagan, P. Lucas, A. Radovic, G. J. Bock, A. V. Devan, M. Orchanian, Juergen Thomas, R. B. Patterson, S. V. Cao, J. J. Evans, M. M. Pfützner, L. Corwin, K. Grzelak, J. Schneps, H. R. Gallagher, R. A. Gomes, J. M. Paley, P. Sail, S. R. Mishra, S. Phan-Budd, A. Sousa, R. Toner, B. Rebel, J. Hartnell, D. D. Phan, S. R. Hahn, N. E. Devenish, J. K. De Jong, I. Anghel, W. A. Mann, M. V. Diwan, P. J. Litchfield, M. M. Medeiros, A. Perch, S. Moed Sher, R. J. Nichol, N. Mayer, A. Schreckenberger, J. Urheim, Karol Lang, R. Zwaska, Carlos Escobar, R. K. Plunkett, X. Qiu, J. A. Nowak, M. A. Thomson, J. A. Musser, D. Naples, Stanley G. Wojcicki, J. Todd, J. O'Connor, J. Hylen, M. C. Goodman, Leigh H. Whitehead, M. Y. Gabrielyan, S. C. Tognini, D. A. Jensen, C. L. McGivern, P. Vahle, D. Bogert, and A. Aurisano
Subjects: Physics, Sterile neutrino, Particle physics, Muon, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, FOS: Physical sciences, General Physics and Astronomy, 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Phenomenology, High Energy Physics - Experiment (hep-ex), Matrix (mathematics), High Energy Physics - Phenomenology (hep-ph), MINOS, 0103 physical sciences, Phenomenological model, High Energy Physics::Experiment, Neutrino, 010306 general physics, Mixing (physics), Beam (structure), QC
Abstract: We report results of a search for oscillations involving a light sterile neutrino over distances of 1.04 and $735\,\mathrm{km}$ in a $\nu_{\mu}$-dominated beam with a peak energy of $3\,\mathrm{GeV}$. The data, from an exposure of $10.56\times 10^{20}\,\textrm{protons on target}$, are analyzed using a phenomenological model with one sterile neutrino. We constrain the mixing parameters $\theta_{24}$ and $\Delta m^{2}_{41}$ and set limits on parameters of the four-dimensional Pontecorvo-Maki-Nakagawa-Sakata matrix, $|U_{\mu 4}|^{2}$ and $|U_{\tau 4}|^{2}$, under the assumption that mixing between $\nu_{e}$ and $\nu_{s}$ is negligible ($|U_{e4}|^{2}=0$). No evidence for $\nu_{\mu} \to \nu_{s}$ transitions is found and we set a world-leading limit on $\theta_{24}$ for values of $\Delta m^{2}_{41} \lesssim 1\,\mathrm{eV}^{2}$., Comment: 7 pages, 4 figures
Published: 2016
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12. Limits on Active to Sterile Neutrino Oscillations from Disappearance Searches in the MINOS, Daya Bay, and Bugey-3 Experiments

Author: Rakesh Sharma, S. Childress, Wenju Huo, H. H. Zhang, D. Cao, A. Schreckenberger, N. Graf, C. D. Moore, R. Gran, Carlos Escobar, Simon Blyth, R. K. Plunkett, X. L. Ji, S. Moed Sher, Haosheng Chen, M. Z. Wang, Ming Chung Chu, D. Torretta, W. Hu, G. J. Bock, J. M. Link, N. Poonthottathil, Jen-Chieh Peng, J. K. Xia, J. Lee, R. W. Hackenburg, S. Zeng, X. Qiu, M. Dolgareva, Carl White, Z. Wang, J. Dove, Chun S. J. Pun, C. M. Castromonte, J. Joshi, J. P. Cummings, M. M. Medeiros, Michael Kramer, L. Corwin, W. J. Wu, R. D. McKeown, P. Sail, Shaomin Chen, Jun Cao, Xuefeng Ding, Z. K. Cheng, Z. P. Zhang, H. L. H. Wong, Y. X. Zhang, X. P. Ji, J. Hartnell, P. Lucas, Hanxiong Huang, S. C. Tognini, Rupert Leitner, M. Qi, Changjian Lin, Gregory J Pawloski, J. Park, L. Kang, J. K. C. Leung, Li Zhou, R. Mehdiyev, K. L. Jen, S. H. Kettell, Yaping Cheng, T. Hu, X. B. Ma, R. B. Patterson, Zhijian Zhang, T. Wise, A. B. Balantekin, S. F. Li, C. Li, Lin Yang, S. R. Mishra, C. James, Yanchu Wang, C. Rosenfeld, X. T. Zhang, M. Mooney, Vit Vorobel, K. Treskov, Dmitry V. Naumov, M. Orchanian, H. Y. Ngai, R. L. Gill, Marco Grassi, Miao He, A. E. Kreymer, D. D. Phan, N. Viaux, S. R. Hahn, Kwong Lau, P. Schreiner, Y. L. Chan, R. Toner, B. Z. Hu, R. Hatcher, D. Cronin-Hennessy, G. X. Sun, B. Rebel, H. A. Rubin, S. K. Lin, J. H. C. Lee, T. Kafka, Jinmei Liu, Jing Zhao, Alec Habig, K. Grzelak, Z. Isvan, L. Mualem, X. Y. Ma, J. Y. Xu, Wei Li, W. A. Mann, F. P. An, T. J. Carroll, P. Adamson, Yanfeng Zhang, S. J. Patton, W. Q. Gu, Y. C. Lin, Mengsu Yang, H. R. Gallagher, Maxim Gonchar, D. W. Liu, Minfang Yeh, Y. Malyshkin, A. Perch, A. Radovic, J. Schneps, I. Mitchell, Harvey B Newman, W. Tang, S. M. S. Kasahara, Marvin L Marshak, X. Wang, P. Gouffon, Liangjian Wen, S. De Rijck, R. A. Johnson, A. Holin, Guofu Cao, Guanghua Gong, X. Tian, Alexander Olshevskiy, M. Bishai, K. T. McDonald, S. Jetter, Haoqi Lu, Dejun Li, W. Flanagan, Wei Wang, B. Roskovec, Jiawen Zhang, Zengcai V. Guo, Y. K. Hor, L. Guo, J. Cheng, Chao Zhang, Jianglai Liu, E. T. Worcester, Z. Lv, F. Z. Qi, H. L. Zhuang, E. Falk, Haijun Yang, J. de Arcos, J. Urheim, Guisen Li, J. J. Cherwinka, G. M. Irwin, Zhiyong Zhang, Honghan Gong, Z. Y. Deng, C. E. Tull, N. Y. Wang, Jinjuan Ren, B. Viren, J. H. Cheng, G. J. Feldman, L. S. Littenberg, C. H. Wu, Zhi Ning, I. Anghel, M. A. Thomson, D. Naples, Stanley G. Wojcicki, Li Chang, Y. Xu, E. C. Huang, Karol Lang, Q. W. Zhao, F. Li, B. R. Littlejohn, H. Y. Wei, Yi-Fang Zhao, G. Koizumi, Qingming Ma, V. Pec, R. L. Talaga, J. J. Ling, Yufeng Li, J. O'Connor, J. Hylen, Y. B. Hsiung, R. J. Nichol, W. L. Zhong, M. C. Goodman, M. V. Frohne, T. Kwok, N. Tagg, N. Mayer, J. B. Jiao, R. A. Gomes, M. C. Sanchez, M. V. Diwan, Guey-Lin Lin, Jonathan S. Lu, Z. Ye, R. B. Pahlka, Qinglong Wu, G.D. Barr, Junwei Huang, Leigh H. Whitehead, Kam Biu Luk, Chunjie Wang, M. Y. Gabrielyan, Siew Cheng Wong, Tian Xue, W. R. Cen, R. T. Lei, K. M. Heeger, J. R. Meier, Xin Qian, Juergen Thomas, Y. K. Heng, Z. M. Wang, Q. J. Li, S. V. Cao, J. A. Nowak, Ran Han, Jiaheng Zou, S. Hans, Mengyun Guan, J. A. Musser, Xiao-yan Li, A. Higuera, X. T. Huang, J. M. Paley, K. Whisnant, Zhi-zhong Xing, Joao A B Coelho, Juan Pedro Ochoa-Ricoux, H. R. Band, K. V. Tsang, H. Liang, Yixue Chen, M. Kordosky, Andrew Blake, J. L. Sun, Artem Chukanov, Lawrence Pinsky, A. Timmons, N. Raper, Richard Rosero, J. F. Chang, Changgen Yang, C. Lu, J. L. Xu, L. H. Whitehead, Ning Zhou, Y. Chang, Shanfeng Li, J. J. Evans, M. M. Pfützner, D. E. Jaffe, Y. Nakajima, Yi Chen, R. C. Webb, M. W. Kwok, L. Lebanowski, Y. Y. Ding, D. M. Xia, J. K. De Jong, S. Phan-Budd, A. Sousa, K. K. Kwan, N. E. Devenish, P. J. Litchfield, R. P. Guo, G. Tzanakos, C. L. McGivern, S. Kohn, S. Germani, Warner A. Miller, A. V. Devan, Bing-Lin Young, D. Bogert, A. Aurisano, W. R. Edwards, E. Naumova, D. A. Dwyer, T. J. Langford, H. M. Steiner, P. Vahle, Y. Q. Ma, Patrick Huber, Shengxin Lin, D. A. Martinez Caicedo, J. K. Nelson, R. G. Wang, D. A. Jensen, Liang Zhan, M. D. Messier, A. C. Weber, X. C. Ruan, Qingmin Zhang, Q. Y. Chen, Jim Napolitano, Xiaohu Guo, M. T. Yang, Hao Pan, C. W. Loh, Z. Y. Yu, Zhibing Li, M. Ye, D. Taychenachev, G. Hussain, J. Todd, P. Jaffke, and R. Chen
Subjects: Physics, Particle physics, Sterile neutrino, Liquid Scintillator Neutrino Detector, 010308 nuclear & particles physics, Physics::Instrumentation and Detectors, High Energy Physics::Phenomenology, General Physics and Astronomy, FOS: Physical sciences, 01 natural sciences, High Energy Physics - Experiment, Nuclear physics, MiniBooNE, High Energy Physics - Experiment (hep-ex), MINOS, 0103 physical sciences, Measurements of neutrino speed, High Energy Physics::Experiment, Neutrino, 010306 general physics, Neutrino oscillation, Electron neutrino, QC
Abstract: Searches for a light sterile neutrino have been performed independently by the MINOS and the Daya Bay experiments using the muon (anti)neutrino and electron antineutrino disappearance channels, respectively. In this Letter, results from both experiments are combined with those from the Bugey-3 reactor neutrino experiment to constrain oscillations into light sterile neutrinos. The three experiments are sensitive to complementary regions of parameter space, enabling the combined analysis to probe regions allowed by the LSND and MiniBooNE experiments in a minimally extended four-neutrino flavor framework. Stringent limits on $\sin^2 2\theta_{\mu e}$ are set over 6 orders of magnitude in the sterile mass-squared splitting $\Delta m^2_{41}$. The sterile-neutrino mixing phase space allowed by the LSND and MiniBooNE experiments is excluded for $\Delta m^2_{41} < 0.8$ eV$^2$ at 95% CL$_s$., Comment: 8 pages, 4 figures, published in Physical Review Letters. Data release found at http://www-numi.fnal.gov/PublicInfo/forscientists.html and at https://wiki.bnl.gov/dayabay/index.php?title=Daya_Bay%27s_Sterile_Neutrino_Results_in_2016
Published: 2016
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13. Measurement of the Multiple-Muon Charge Ratio in the MINOS Far Detector

Author: X. Tian, M. L. Marshak, A. C. Weber, G. M. Irwin, H. A. Rubin, C. White, M. Kordosky, Andrew Blake, M. A. Thomson, D. Naples, Stanley G. Wojcicki, G. J. Feldman, A. Timmons, J. O'Connor, J. Hylen, M. C. Goodman, R. B. Patterson, R. Hatcher, L. Corwin, S. Moed Sher, L. H. Whitehead, R. Mehdiyev, J. R. Meier, J. Schneps, I. Anghel, M. V. Diwan, A. Schreckenberger, S. C. Tognini, S. R. Mishra, W. H. Miller, M. D. Messier, Carlos Escobar, R. K. Plunkett, N. Graf, R. Gran, J. A. Nowak, N. Tagg, X. Qiu, P. Schreiner, D. D. Phan, M. M. Medeiros, P. J. Litchfield, A. Holin, G.D. Barr, Junwei Huang, S. Phan-Budd, C. L. McGivern, J. Todd, A. Sousa, M. Bishai, N. E. Devenish, W. A. Mann, T. Kafka, Juergen Thomas, G. Tzanakos, D. Cronin-Hennessy, E. Falk, M. Orchanian, G. Koizumi, P. Gouffon, Z. Isvan, K. Grzelak, R. Chen, Rakesh Sharma, R. J. Nichol, L. Mualem, Joao A B Coelho, B. Viren, S. Childress, N. Mayer, S. Germani, C. D. Moore, R. L. Talaga, A. V. Devan, P. Vahle, Leigh H. Whitehead, D. Torretta, P. Lucas, Alec Habig, J. Hartnell, S. R. Hahn, C. M. Castromonte, J. K. Nelson, P. Sail, D. Bogert, D. A. Jensen, Karol Lang, A. E. Kreymer, M. V. Frohne, H. R. Gallagher, A. Aurisano, R. C. Webb, S. M. S. Kasahara, J. K. De Jong, A. Radovic, N. Poonthottathil, S. V. Cao, A. Perch, J. M. Paley, J. J. Evans, M. M. Pfützner, J. Urheim, J. A. Musser, T. J. Carroll, Harvey B Newman, M. Gabrielyan, R. Zwaska, C. Rosenfeld, P. Adamson, R. A. Gomes, Gregory J Pawloski, C. James, R. Toner, B. Rebel, G. J. Bock, W. Flanagan, S. De Rijck, M. C. Sanchez, and R. B. Pahlka
Subjects: Physics, Particle physics, Muon, Physics - Instrumentation and Detectors, 010308 nuclear & particles physics, Physics::Instrumentation and Detectors, Detector, FOS: Physical sciences, Charge (physics), Instrumentation and Detectors (physics.ins-det), 01 natural sciences, Magnetic field, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), MINOS, 0103 physical sciences, Muon flux, High Energy Physics::Experiment, 010306 general physics, Independent data, QC
Abstract: The charge ratio, $R_\mu = N_{\mu^+}/N_{\mu^-}$, for cosmogenic multiple-muon events observed at an under- ground depth of 2070 mwe has been measured using the magnetized MINOS Far Detector. The multiple-muon events, recorded nearly continuously from August 2003 until April 2012, comprise two independent data sets imaged with opposite magnetic field polarities, the comparison of which allows the systematic uncertainties of the measurement to be minimized. The multiple-muon charge ratio is determined to be $R_\mu = 1.104 \pm 0.006 {\rm \,(stat.)} ^{+0.009}_{-0.010} {\rm \,(syst.)} $. This measurement complements previous determinations of single-muon and multiple-muon charge ratios at underground sites and serves to constrain models of cosmic ray interactions at TeV energies., Comment: 10 pages, 2 figures
Published: 2016
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14. Search for Sterile Neutrinos Mixing with Muon Neutrinos in MINOS

Author: Adamson, P. Anghel, I. Aurisano, A. Barr, G. Bishai, M. and Blake, A. Bock, G. J. Bogert, D. Cao, S. V. Carroll, T. J. Castromonte, C. M. Chen, R. Childress, S. Coelho, J. A. B. Corwin, L. Cronin-Hennessy, D. de Jong, J. K. and De Rijck, S. Devan, A. V. Devenish, N. E. Diwan, M. V. and Escobar, C. O. Evans, J. J. Falk, E. Feldman, G. J. and Flanagan, W. Frohne, M. V. Gabrielyan, M. Gallagher, H. R. and Germani, S. Gomes, R. A. Goodman, M. C. Gouffon, P. and Graf, N. Gran, R. Grzelak, K. Habig, A. Hahn, S. R. and Hartnell, J. Hatcher, R. Holin, A. Huang, J. Hylen, J. and Irwin, G. M. Isvan, Z. James, C. Jensen, D. Kafka, T. Kasahara, S. M. S. Koizumi, G. Kordosky, M. Kreymer, A. Lang, K. Ling, J. Litchfield, P. J. Lucas, P. and Mann, W. A. Marshak, M. L. Mayer, N. McGivern, C. and Medeiros, M. M. Mehdiyev, R. Meier, J. R. Messier, M. D. and Miller, W. H. Mishra, S. R. Sher, S. Moed Moore, C. D. and Mualem, L. Musser, J. Naples, D. Nelson, J. K. Newman, H. B. Nichol, R. J. Nowak, J. A. O'Connor, J. Orchanian, M. Pahlka, R. B. Paley, J. Patterson, R. B. Pawloski, G. and Perch, A. Pfuetzner, M. M. Phan, D. D. Phan-Budd, S. and Plunkett, R. K. Poonthottathil, N. Qiu, X. Radovic, A. and Rebel, B. Rosenfeld, C. Rubin, H. A. Sail, P. Sanchez, M. C. Schneps, J. Schreckenberger, A. Schreiner, P. and Sharma, R. Sousa, A. Tagg, N. Talaga, R. L. Thomas, J. and Thomson, M. A. Tian, X. Timmons, A. Todd, J. and Tognini, S. C. Toner, R. Torretta, D. Tzanakos, G. and Urheim, J. Vahle, P. Viren, B. Weber, A. Webb, R. C. and White, C. Whitehead, L. Whitehead, L. H. Wojcicki, S. G. and Zwaska, R. MINOS Collaboration
Subjects: High Energy Physics::Phenomenology, High Energy Physics::Experiment
Abstract: We report results of a search for oscillations involving a light sterile neutrino over distances of 1.04 and 735 km in a nu(mu)-dominated beam with a peak energy of 3 GeV. The data, from an exposure of 10.56 x 10(20) protons on target, are analyzed using a phenomenological model with one sterile neutrino. We constrain the mixing parameters theta(24) and Delta m(41)(2) and set limits on parameters of the four-dimensional Pontecorvo-Maki-Nakagawa-Sakata matrix, vertical bar U-mu 4 vertical bar(2) and vertical bar U-tau 4 vertical bar(2), under the assumption that mixing between nu(e) and nu(s) is negligible (vertical bar U-e4 vertical bar(2) = 0). No evidence for nu(mu) -> nu(s) transitions is found and we set a world-leading limit on theta(24) for values of Delta m(41)(2) less than or similar to 1 eV(2).
Published: 2016

15. Measurement of the multiple-muon charge ratio in the MINOS Far Detector

Author: Adamson, P. Anghel, I. Aurisano, A. Barr, G. Bishai, M. and Blake, A. Bock, G. J. Bogert, D. Cao, S. V. Carroll, T. J. Castromonte, C. M. Chen, R. Childress, S. Coelho, J. A. B. Corwin, L. Cronin-Hennessy, D. de Jong, J. K. and De Rijck, S. Devan, A. V. Devenish, N. E. Diwan, M. V. and Escobar, C. O. Evans, J. J. Falk, E. Feldman, G. J. and Flanagan, W. Frohne, M. V. Gabrielyan, M. Gallagher, H. R. and Germani, S. Gomes, R. A. Goodman, M. C. Gouffon, P. and Graf, N. Gran, R. Grzelak, K. Habig, A. Hahn, S. R. and Hartnell, J. Hatcher, R. Holin, A. Huang, J. Hylen, J. and Irwin, G. M. Isvan, Z. James, C. Jensen, D. Kafka, T. Kasahara, S. M. S. Koizumi, G. Kordosky, M. Kreymer, A. Lang, K. Ling, J. Litchfield, P. J. Lucas, P. and Mann, W. A. Marshak, M. L. Mayer, N. McGivern, C. and Medeiros, M. M. Mehdiyev, R. Meier, J. R. Messier, M. D. and Miller, W. H. Mishra, S. R. Sher, S. Moed Moore, C. D. and Mualem, L. Musser, J. Naples, D. Nelson, J. K. Newman, H. B. Nichol, R. J. Nowak, J. A. O'Connor, J. Orchanian, M. Pahlka, R. B. Paley, J. Patterson, R. B. Pawloski, G. and Perch, A. Pfuetzner, M. M. Phan, D. D. Phan-Budd, S. and Plunkett, R. K. Poonthottathil, N. Qiu, X. Radovic, A. and Rebel, B. Rosenfeld, C. Rubin, H. A. Sail, P. Sanchez, M. C. Schneps, J. Schreckenberger, A. Schreiner, P. and Sharma, R. Sousa, A. Tagg, N. Talaga, R. L. Thomas, J. and Thomson, M. A. Tian, X. Timmons, A. Todd, J. and Tognini, S. C. Toner, R. Torretta, D. Tzanakos, G. and Urheim, J. Vahle, P. Viren, B. Weber, A. Webb, R. C. and White, C. Whitehead, L. Whitehead, L. H. Wojcicki, S. G. and Zwaska, R. MINOS Collaboration
Subjects: Physics::Instrumentation and Detectors, High Energy Physics::Experiment
Abstract: The charge ratio, R-mu = N mu+/N mu-, for cosmogenic multiple-muon events observed at an underground depth of 2070 mwe has been measured using the magnetized MINOS Far Detector. The multiple-muon events, recorded nearly continuously from August 2003 until April 2012, comprise two independent data sets imaged with opposite magnetic field polarities, the comparison of which allows the systematic uncertainties of the measurement to be minimized. The multiple-muon charge ratio is determined to be R mu = 1.104 +/- 0.006(stat)(-0.010)(+0.009) (syst). This measurement complements previous determinations of single-muon and multiple-muon charge ratios at underground sites and serves to constrain models of cosmic-ray interactions at TeV energies.
Published: 2016

16. Measurement of single pi(0) production by coherent neutral-current nu Fe interactions in the MINOS Near Detector

Author: Adamson, P. Anghel, I. Aurisano, A. Barr, G. Bishai, M. and Blake, A. Bock, G. J. Bogert, D. Cao, S. V. Carroll, T. J. Castromonte, C. M. Chen, R. Cherdack, D. and Childress, S. Coelho, J. A. B. Corwin, L. Cronin-Hennessy, D. de Jong, J. K. De Rijck, S. Devan, A. V. Devenish, N. E. Diwan, M. V. Escobar, C. O. Evans, J. J. Falk, E. and Feldman, G. J. Flanagan, W. Frohne, M. V. Gabrielyan, M. and Gallagher, H. R. Germani, S. Gomes, R. A. Goodman, M. C. and Gouffon, P. Graf, N. Gran, R. Grzelak, K. Habig, A. and Hahn, S. R. Hartnell, J. Hatcher, R. Holin, A. Huang, J. and Hylen, J. Irwin, G. M. Isvan, Z. James, C. Jensen, D. Kafka, T. Kasahara, S. M. S. Koizumi, G. Kordosky, M. and Kreymer, A. Lang, K. Ling, J. Litchfield, P. J. and Lucas, P. Mann, W. A. Marshak, M. L. Mayer, N. McGivern, C. Medeiros, M. M. Mehdiyev, R. Meier, J. R. Messier, M. D. Miller, W. H. Mishra, S. R. Sher, S. Moed Moore, C. D. Mualem, L. Musser, J. Naples, D. Nelson, J. K. and Newman, H. B. Nichol, R. J. Nowak, J. A. O'Connor, J. and Oliver, W. P. Orchanian, M. Pahlka, R. B. Paley, J. and Patterson, R. B. Pawloski, G. Perch, A. Pfutzner, M. M. and Phan, D. D. Phan-Budd, S. Plunkett, R. K. Poonthottathil, N. and Qiu, X. Radovic, A. Rebel, B. Rosenfeld, C. Rubin, H. A. Sail, P. Sanchez, M. C. Schneps, J. and Schreckenberger, A. Schreiner, P. Sharma, R. Sousa, A. and Tagg, N. Talaga, R. L. Thomas, J. Thomson, M. A. Tian, X. Timmons, A. Todd, J. Tognini, S. C. Toner, R. and Torretta, D. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. and Weber, A. Webb, R. C. White, C. Whitehead, L. and Whitehead, L. H. Wojcicki, S. G. Zwaska, R. MINOS Collaboration and Adamson, P. Anghel, I. Aurisano, A. Barr, G. Bishai, M. and Blake, A. Bock, G. J. Bogert, D. Cao, S. V. Carroll, T. J. Castromonte, C. M. Chen, R. Cherdack, D. and Childress, S. Coelho, J. A. B. Corwin, L. Cronin-Hennessy, D. de Jong, J. K. De Rijck, S. Devan, A. V. Devenish, N. E. Diwan, M. V. Escobar, C. O. Evans, J. J. Falk, E. and Feldman, G. J. Flanagan, W. Frohne, M. V. Gabrielyan, M. and Gallagher, H. R. Germani, S. Gomes, R. A. Goodman, M. C. and Gouffon, P. Graf, N. Gran, R. Grzelak, K. Habig, A. and Hahn, S. R. Hartnell, J. Hatcher, R. Holin, A. Huang, J. and Hylen, J. Irwin, G. M. Isvan, Z. James, C. Jensen, D. Kafka, T. Kasahara, S. M. S. Koizumi, G. Kordosky, M. and Kreymer, A. Lang, K. Ling, J. Litchfield, P. J. and Lucas, P. Mann, W. A. Marshak, M. L. Mayer, N. McGivern, C. Medeiros, M. M. Mehdiyev, R. Meier, J. R. Messier, M. D. Miller, W. H. Mishra, S. R. Sher, S. Moed Moore, C. D. Mualem, L. Musser, J. Naples, D. Nelson, J. K. and Newman, H. B. Nichol, R. J. Nowak, J. A. O'Connor, J. and Oliver, W. P. Orchanian, M. Pahlka, R. B. Paley, J. and Patterson, R. B. Pawloski, G. Perch, A. Pfutzner, M. M. and Phan, D. D. Phan-Budd, S. Plunkett, R. K. Poonthottathil, N. and Qiu, X. Radovic, A. Rebel, B. Rosenfeld, C. Rubin, H. A. Sail, P. Sanchez, M. C. Schneps, J. and Schreckenberger, A. Schreiner, P. Sharma, R. Sousa, A. and Tagg, N. Talaga, R. L. Thomas, J. Thomson, M. A. Tian, X. Timmons, A. Todd, J. Tognini, S. C. Toner, R. and Torretta, D. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. and Weber, A. Webb, R. C. White, C. Whitehead, L. and Whitehead, L. H. Wojcicki, S. G. Zwaska, R. MINOS Collaboration
Abstract: Forward single pi(0) production by coherent neutral-current interactions, vA -> vA pi(0), is investigated using a 2.8 x 10(20) protons-on-target exposure of the MINOS Near Detector. For single-shower topologies, the event distribution in production angle exhibits a clear excess above the estimated background at very forward angles for visible energy in the range 1-8 GeV. Cross sections are obtained for the detector medium comprised of 80% iron and 20% carbon nuclei with (A) = 48, the highest-< A > target used to date in the study of this coherent reaction. The total cross section for coherent neutral-current single pi(0) production initiated by the v(mu) flux of the NuMI low-energy beam with mean (mode) E-v of 4.9 GeV (3.0 GeV), is 77.6 +/- 5.0 (stat)(-) (+15.0)(16.8) (syst) x 10(-40) cm(2) pernucleus. The results are in good agreement with predictions of the Berger-Sehgal model.
Published: 2016

17. Detecting Induced p±ip Pairing at the Al-InAs Interface with a Quantum Microwave Circuit.

Author: Phan D, Senior J, Ghazaryan A, Hatefipour M, Strickland WM, Shabani J, Serbyn M, and Higginbotham AP
Abstract: Superconductor-semiconductor hybrid devices are at the heart of several proposed approaches to quantum information processing, but their basic properties remain to be understood. We embed a two-dimensional Al-InAs hybrid system in a resonant microwave circuit, probing the breakdown of superconductivity due to an applied magnetic field. We find a fingerprint from the two-component nature of the hybrid system, and quantitatively compare with a theory that includes the contribution of intraband p±ip pairing in the InAs, as well as the emergence of Bogoliubov-Fermi surfaces due to magnetic field. Separately resolving the Al and InAs contributions allows us to determine the carrier density and mobility in the InAs.
Published: 2022
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18. Point-of-care Hepatitis C virus testing and linkage to treatment in an Australian inner-city emergency department.

Author: Hutton J, Doyle J, Zordan R, Weiland T, Cocco A, Howell J, Iser S, Snell J, Fry S, New K, Sloane R, Jarman M, Phan D, Tran S, Pedrana A, Williams B, Johnson J, Glasgow S, and Thompson A
Subjects: Adult, Antiviral Agents administration & dosage, Australia, Female, Follow-Up Studies, Hepacivirus isolation & purification, Hepatitis C drug therapy, Hepatitis C epidemiology, Ill-Housed Persons statistics & numerical data, Humans, Male, Mass Screening methods, Mass Screening statistics & numerical data, Middle Aged, Prospective Studies, RNA, Viral analysis, Risk Factors, Substance Abuse, Intravenous epidemiology, Emergency Service, Hospital, Hepatitis C diagnosis, Point-of-Care Systems, Substance Abuse, Intravenous complications
Abstract: Background: In Australia, Hepatitis C Virus (HCV) treatment is declining, despite broad access to direct-acting antiviral medication. People who inject drugs are proportionally over-represented in emergency department presentations. Emergency department assessment of people who have injected drugs for HCV presents an opportunity to engage this marginalised population with treatment. We describe the outcomes of risk-based screening and point-of-care anti-HCV testing for emergency department patients, and linkage to outpatient antiviral treatment., Methods: During the three-month study period, consecutive adult patients who presented to the emergency department during the study times were screened for risk factors and offered the OraQuick oral HCV antibody test. Those with reactive results were offered venepuncture in the emergency department for confirmatory testing and direct-acting antiviral treatment in clinic. The main outcome measures were the number and proportion of viremic participants that were linked to the hepatitis clinic, commenced treatment and achieved a sustained viral response. Secondary outcome measures were the proportion (%) of presentations screened that were oral antibody reactive, and the prevalence and type of HCV risk factors., Results: During the study period, 2408 of the 3931 (61%) presentations to the emergency department were eligible for screening. Of these 2408 patients, 1122 (47%) participated, 307 (13%) declined participation and 977 (41%) could not be approached during their time in the emergency department. Among the 1122 participants, 378 (34%) reported at least one risk factor. Subsequently, 368 (97%) of the 378 participants underwent OraQuick anti-HCV test, and 50 (14%) had a reactive result. A risk factor of ever having injected drugs was present in 44 (88%) of participants who were sero-positive. Of the 45 that had blood tested, 30 (67%) were HCV ribonucleic acid (RNA) positive. Three participants died. Of the 27 remaining participants, 10 (37%) commenced treatment and 7 of these 10 (70%) obtained a cure. There was a high rate of homelessness (24%) among anti-HCV positive participants., Conclusion: Among emergency department participants with a risk factor for HCV, positive serology was common using a rapid point-of-care test. A history of injecting drug use was identified as the risk factor with highest yield for positive HCV serology, and is suitable as a single screening question. However, linkage to care post ED presentation was low in this marginalised population. There is a need for new pathways to improve the care cascade for marginalised individuals living with HCV infection., (Copyright © 2019 Elsevier B.V. All rights reserved.)
Published: 2019
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19. The influence of sagittal spinal deformity on anteversion of the acetabular component in total hip arthroplasty.

Author: Phan D, Bederman SS, and Schwarzkopf R
Subjects: Hip Prosthesis, Humans, Lumbosacral Region physiopathology, Pelvic Bones physiopathology, Posture physiology, Acetabulum surgery, Arthroplasty, Replacement, Hip methods, Spinal Diseases physiopathology
Abstract: The interaction between the lumbosacral spine and the pelvis is dynamically related to positional change, and may be complicated by co-existing pathology. This review summarises the current literature examining the effect of sagittal spinal deformity on pelvic and acetabular orientation during total hip arthroplasty (THA) and provides recommendations to aid in placement of the acetabular component for patients with co-existing spinal pathology or long spinal fusions. Pre-operatively, patients can be divided into four categories based on the flexibility and sagittal balance of the spine. Using this information as a guide, placement of the acetabular component can be optimal based on the type and significance of co-existing spinal deformity., (©2015 The British Editorial Society of Bone & Joint Surgery.)
Published: 2015
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20. [Early detection of smoking related chronic obstructive pulmonary disease in Vietnam].

Author: Duong-Quy S, Hua-Huy T, Mai-Huu-Thanh B, Doan-Thi-Quynh N, Le-Quang K, Nguyen-Van H, Phan-Van D, Tran-Dinh H, Reboud P, Dinh-Xuan AT, and Homasson JP
Subjects: Adult, Aged, Feasibility Studies, Female, Forced Expiratory Volume, Humans, Male, Mass Screening, Middle Aged, Predictive Value of Tests, Pulmonary Disease, Chronic Obstructive epidemiology, Pulmonary Disease, Chronic Obstructive etiology, Sensitivity and Specificity, Spirometry, Vietnam epidemiology, Early Diagnosis, Pulmonary Disease, Chronic Obstructive diagnosis, Smoking adverse effects
Abstract: Introduction: Epidemiological studies of chronic obstructive pulmonary disease (COPD) are rare in the developing countries, particularly in Viet Nam where the consumption of tobacco continues to increase. The aim of this study was to evaluate the feasibility of early screening of smokers for bronchial obstruction using the Piko-6 apparatus., Materials and Methods: Smokers over 40 years of age who had smoked for more than 10 years were included. The subjects were classified into 3 groups according to the degree of bronchial obstruction measured by the Piko-6. (group 1: FEV1/FEV6>0.8; group 2: 0.7-0.8; group 3:<0.7). The smokers in group 3 and a sample of the smokers in groups 1 and 2 were recalled for full spirometric assessment., Results: 2397 smokers were included, comprising 2130 active smokers and 267 ex-smokers. The mean age was 52 +/- 13 years. The mean smoking history was 24 +/- 13 pack years. 267 smokers from the 3 groups responded to the recall for full investigation. The prevalence of COPD detected by the Piko-6 in the study population was 13.5%. For the threshold FEV1/FEV6<0.7 and with the detected prevalence, the Piko-6 had a sensitivity of 97.8%, a specificity of 93.8%, a positive predictive value of 71% and a negative predictive value of 99.6% (confidence interval 95%)., Conclusions: The Piko-6 is a useful tool for the early screening for COPD in smokers in a developing country where the prevalence of this disease appears to be under estimated.
Published: 2009
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21. Arabinoxylan-lipid-based edible films and coatings. 3. Influence of drying temperature on film structure and functional properties.

Author: Phan The D, Debeaufort F, Péroval C, Despré D, Courthaudon JL, and Voilley A
Subjects: Chemical Phenomena, Chemistry, Physical, Desiccation, Drug Stability, Food Industry, Palm Oil, Permeability, Plant Oils, Water, Xylans, Zea mays chemistry, Emulsions chemistry, Food Technology, Lipids, Temperature
Abstract: This work is a contribution to better knowledge of the influence of the structure of films obtained from emulsions based on arabinoxylans, hydrogenated palm kernel oil, and emulsifiers on their functional properties. The sucrose esters (emulsifiers) have a great effect on the stabilization of the emulsified film structure containing arabinoxylans and hydrogenated palm kernel oil. The structure and stability of the emulsion during drying strongly affect barrier and mechanical properties of films. The higher are creaming and coalescence phenomena in films, the lower is the water vapor permeability. Emulsion destabilization is favored by high drying temperature and tends to give films having a "bilayer-like" structure, which tends to improve the functional properties of arabinoxylans-based edible films.
Published: 2002
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22. Arabinoxylan-lipids-based edible films and coatings. 2. Influence of sucroester nature on the emulsion structure and film properties.

Author: Phan The D, Péroval C, Debeaufort F, Despré D, Courthaudon JL, and Voilley A
Subjects: Absorption, Chemical Phenomena, Chemistry, Physical, Emulsions, Esterification, Food Packaging, Palm Oil, Permeability, Surface Properties, Water, Esters chemistry, Plant Oils chemistry, Xylans chemistry
Abstract: This work is a contribution to better knowledge of the influence of the structure of films on their functional properties obtained from emulsions based on arabinoxylans, hydrogenated palm kernel oil (HPKO), and emulsifiers. The sucroesters (emulsifiers) have a great effect on the stabilization of the emulsified film structure containing arabinoxylans and hydrogenated palm kernel oil. They improve the moisture barrier properties. Several sucroesters having different esterification degrees were tested. Both lipophilic (90% of di and tri-ester) and hydrophilic (70% of mono-ester) sucrose esters can ensure the stability of the emulsion used to form the film, especially during preparation and drying. These emulsifiers confer good moisture barrier properties to emulsified films.
Published: 2002
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23. Androgen regulation of the cell-cell adhesion molecule-1 (Ceacam1) gene.

Author: Phan D, Sui X, Chen DT, Najjar SM, Jenster G, and Lin SH
Subjects: Animals, Antigens, CD drug effects, Antigens, Differentiation drug effects, Binding Sites genetics, Cell Adhesion Molecules, DNA-Binding Proteins physiology, HeLa Cells, Humans, Mutagenesis, Site-Directed, Promoter Regions, Genetic drug effects, Rats, Receptors, Androgen genetics, Receptors, Androgen metabolism, Receptors, Androgen physiology, Transfection, Androgens physiology, Antigens, CD genetics, Antigens, Differentiation genetics, Gene Expression Regulation drug effects
Abstract: Previous studies have established that the cell-cell adhesion molecule-1 (CEACAM1, previously known as C-CAM1) functions as a tumor suppressor in prostate cancer and is involved in the regulation of prostate growth and differentiation. However, the molecular mechanism that modulates CEACAM1 expression in the prostate is not well defined. Since the growth of prostate epithelial cells is androgen-regulated, we investigated the effects of androgen and the androgen receptor (AR) on CEACAM1 expression. Transient transfection experiments showed that the AR can enhance the Ceacam1 promoter activity in a ligand-dependent manner and that the regulatory element resides within a relatively short (-249 to -194 bp) segment of the 5'-flanking region of the Ceacam1 gene. This androgen regulation is likely through direct AR-promoter binding because a mutant AR defective in DNA binding failed to upregulate reporter gene expression. Furthermore, electrophoretic mobility shift assays demonstrated that the AR specifically binds to this sequence, and mutation analysis of the potential ARE sequences revealed a region within the sequence that was required for the AR to activate the Ceacam1 gene. Therefore, the regulation of Ceacam1 gene expression by androgen may be one of the mechanisms by which androgen regulates prostatic function.
Published: 2001
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24. Differences in tissue-specific and embryonic expression of mouse Ceacam1 and Ceacam2 genes.

Author: Han E, Phan D, Lo P, Poy MN, Behringer R, Najjar SM, and Lin SH
Subjects: Amino Acid Sequence, Animals, Base Sequence, Carcinoembryonic Antigen, DNA, Complementary, Glycoproteins, Male, Mice, Molecular Sequence Data, Sequence Homology, Amino Acid, Testis metabolism, Adenosine Triphosphatases genetics, Antigens, CD genetics, Antigens, Differentiation genetics, Cell Adhesion Molecules genetics, Embryonic and Fetal Development genetics
Abstract: The intercellular adhesion molecule CEACAM1, also known as C-CAM1 (where CAM is cell-adhesion molecule), can function as a tumour suppressor in several carcinomas, including those of the prostate, breast, bladder and colon. This suggests that CEACAM1 may play an important role in the regulation of normal cell growth and differentiation. However, there is no direct evidence to support this putative function of CEACAM1. To elucidate its physiological function by targeted gene deletion, we isolated the Ceacam genes from a mouse 129 Sv/Ev library. Although there is only one Ceacam1 gene in humans and one in rats, two homologous genes (Ceacam1 and Ceacam2) have been identified in the mouse. Our sequence analysis revealed that the genes encoded nine exons and spanned approx. 16-17 kb (Ceacam1) and 25 kb (Ceacam2). The genes were highly similar (79.6%). The major differences in the protein-coding regions were located in exons 2, 5 and 6 (76.9%, 87.0% and 78.5% similarity respectively). In addition, introns 2, 5 and 7 were also significantly different, being 29.7%, 59.8% and 64.5% similar respectively. While most of these differences were due to nucleotide substitutions, two insertions of 418 and 5849 bp occurred in intron 2 of Ceacam2, and another two insertions of 1384 and 197 bp occurred in introns 5 and 7 respectively. To determine whether functional redundancy exists between Ceacam1 and Ceacam2, we examined their expression in 16 mouse tissues by using semi-quantitative reverse transcription-PCR. As in human and rat, in the mouse Ceacam1 mRNA was highly abundant in the liver, small intestine, prostate and spleen. In contrast, Ceacam2 mRNA was only detected in kidney, testis and, to a lesser extent, spleen. Reverse transcription-PCR using testis RNA indicated that Ceacam2 in the testis is an alternatively spliced form containing only exons 1, 2, 5, 6, 8 and 9. In the mouse embryo, Ceacam1 mRNA was detected at day 8.5, disappeared between days 9.5 and 12.5, and re-appeared at day 19. On the other hand, no Ceacam2 mRNA was detected throughout embryonic development. The different tissue expression patterns and regulation during embryonic development suggest that the CEACAM1 and CEACAM2 proteins, although highly similar, may have different functions both during mouse development and in adulthood.
Published: 2001
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25. Purification and characterization of human cell--cell adhesion molecule 1 (C-CAM1) expressed in insect cells.

Author: Phan D, Han E, Birrell G, Bonnal S, Duggan L, Esumi N, Gutstein H, Li R, Lopato S, Manogaran A, Pollak ES, Ray A, Reddi PP, Reichert AS, Struffi P, Tiscornia G, Ximenez-Fyvie LA, Zhang H, and Lin SH
Subjects: Adenosine Triphosphatases chemistry, Adenosine Triphosphatases genetics, Amidohydrolases metabolism, Amino Acid Sequence, Animals, Antigens, CD, Baculoviridae genetics, Blotting, Western, Cell Adhesion, Cell Adhesion Molecules chemistry, Cell Adhesion Molecules genetics, Cell Line, Cell Size, Chromatography, Affinity, Glycosylation, Humans, Nickel metabolism, Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase, Recombinant Proteins chemistry, Recombinant Proteins isolation & purification, Recombinant Proteins metabolism, Sequence Analysis, Protein, Adenosine Triphosphatases isolation & purification, Adenosine Triphosphatases metabolism, Cell Adhesion Molecules isolation & purification, Cell Adhesion Molecules metabolism, Spodoptera cytology, Spodoptera metabolism, Spodoptera virology
Abstract: The cell--cell adhesion molecule 1 (C-CAM1) plays an important role as a tumor suppressor for prostate cancer. Decreased expression of C-CAM1 was detected in prostate, breast, and colon carcinoma. Reexpression of C-CAM1 in prostate and breast cancer cell lines was able to suppress tumorigenicity in vivo. These observations suggest that C-CAM1 may be used as a marker for cancer detection or diagnosis. To generate monoclonal antibodies specific to C-CAM1, we have overexpressed full-length human C-CAM1 in Sf9 cells using a baculovirus expression system. The protein was purified 104-fold using nickel affinity chromatography. About 0.4 mg purified C-CAM1 was obtained from 200 mg of infected cells. When the purified protein was digested with peptidyl-N-glycosidase, the apparent mobility of the protein on SDS--PAGE changed from 90 to 58 kDa, which is close to the molecular weight predicted from the cloned cDNA sequence. This observation suggests that C-CAM1 was glycosylated on asparagine residues when expressed in Sf9 cells. Western blotting and internal protein sequencing analysis confirmed that the purified protein is human C-CAM1. Biochemical and functional assays indicate that this protein expressed in Sf9 cells displays characteristics similar to those of native protein, including adhesion function and glycosylation modification. Using this protocol, sufficient quantity of this protein can be produced with purity suitable for monoclonal antibody generation and biochemical study., (Copyright 2001 Academic Press.)
Published: 2001
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26. The cytoplasmic domain of C-CAM1 tumor suppressor is necessary and sufficient for suppressing the tumorigenicity of prostate cancer cells.

Author: Estrera VT, Luo W, Phan D, Earley K, Hixson DC, and Lin SH
Subjects: Adenosine Triphosphatases genetics, Adenoviridae, Animals, Antigens, CD, Carcinoembryonic Antigen, Cell Adhesion, Cell Adhesion Molecules genetics, Cell Aggregation, Cell Division, Cloning, Molecular, Cytoplasm metabolism, Genetic Vectors, Glycoproteins, Humans, Male, Mice, Mice, Nude, Mutagenesis, Site-Directed, Recombinant Proteins chemistry, Recombinant Proteins metabolism, Transfection, Adenosine Triphosphatases chemistry, Adenosine Triphosphatases physiology, Cell Adhesion Molecules chemistry, Cell Adhesion Molecules physiology, Prostatic Neoplasms pathology, Prostatic Neoplasms physiopathology
Abstract: We have previously shown that C-CAM1 cell adhesion molecule can suppress the growth of prostate cancer cells in vivo. In this study, we determined the minimal domain of C-CAM1 that is required for its tumor-suppressive activity. DU145 prostate cancer cells were infected with recombinant adenoviruses containing various C-CAM1 mutant genes, and the effects of the mutant C-CAM1 proteins on the growth of DU145 cells were assessed in a nude-mice xenograft model. Deletion of C-CAM1's cytoplasmic domain, which is not required for its adhesion activity, abolished the growth-suppressive activity, whereas deletion of the adhesion domain did not. This observation suggests that C-CAM1's extracellular domain may be not essential for its tumor suppressive activity. Indeed, we found that expression of the C-CAM1 cytoplasmic domain alone led to growth suppression of DU145 cells. These results suggest that the cytoplasmic domain of C-CAM1 is necessary and sufficient for its growth-suppressive function., (Copyright 1999 Academic Press.)
Published: 1999
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27. [Bloody nipple discharge in infants and young children].

Author: Phan D, N'Guyêt H, and David L
Subjects: Child, Preschool, Female, Humans, Infant, Male, Breast Diseases blood, Nipples metabolism
Published: 1996
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28. pH dependent binding of high and low affinity myelin basic protein peptides to purified HLA-DR2.

Author: Mukku PV, Passmore D, Phan D, and Nag B
Subjects: Amino Acid Sequence, Cell Line, Enzyme-Linked Immunosorbent Assay, Humans, Hydrogen-Ion Concentration, Molecular Sequence Data, Protein Binding physiology, HLA-DR2 Antigen metabolism, Myelin Basic Protein chemistry, Myelin Basic Protein metabolism, Peptides chemistry, Peptides metabolism
Abstract: Major histocompatibility complex (MHC) class II molecules are cell surface glycoproteins and are known to display processed antigens on the surface of antigen presenting cells (APC). Within the APC, the loading of processed antigenic peptides to MHC class II molecules is known to take place in the endosomal compartment at acidic pH environment. The present study describes the in vitro effect of pH on binding of four biotinylated myelin basic protein (MBP) peptides to affinity purified HLA-DR2 containing a mixture of DRB1*1501 and DRB5*0101 beta chain. The binding affinity of the selected peptides are in the order of MBP(83-102)Y83 > MBP(124-143) > MBP(143-168) > MBP(1-14). Most of these peptides in association with HLA-DR2 are considered as immunodominant epitopes for human multiple sclerosis autoimmune disorder. One epitope, MBP(1-14), had almost no affinity to purified HLA-DR2 and was used as a control peptide in all binding assays. The quantitation of the bound peptide at various pH was carried out by antibody capture of complexes followed by avidin-alkaline phosphatase detection system. Among four peptides tested, only the highest affinity MBP(83-102)Y83 peptide showed maximum binding to purified HLA-DR2 at acidic pH. Two other epitopes, MBP(124-143) and MBP(143-168), showed maximum binding at basic and neutral pH values, respectively. The binding of only high affinity peptides, MBP(83-102)Y83 and MBP(124-143), was significantly affected by changing the pH of the binding buffer. Such alteration in pH of the binding buffer resulted in 100% occupancy of DR2 with both high affinity MBP peptides. In contrast, no significant increase in binding of the low affinity MBP(143-168) peptide was observed at altered pH values. The specificity of the increased binding of high affinity peptides to HLA-DR2 at optimum pH was demonstrated by competitive binding assays using non-biotinylated peptides. Finally, the stability of various MBP peptide bound complexes was tested at 4 degrees, 25 degrees and 37 degrees C which correlates well with their affinity to HLA-DR2. These results suggest that pH plays an important role in in vitro binding of antigenic peptides and such manipulation of binding conditions can be utilized in generating 100% loaded MHC class II with high affinity antigenic peptides. Since high affinity peptides are generally considered as major immunodominant epitopes, the in vitro pH dependent binding can be utilized in screening immunodominant epitopes of various autoantigens and generating complexes of defined composition.
Published: 1995
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29. Antigenic peptide binding to MHC class II molecules at increased peptide concentrations.

Author: Nag B, Mukku PV, Arimilli S, Phan D, Deshpande SV, and Winkelhake JL
Subjects: Amino Acid Sequence, Antibodies, Monoclonal immunology, Binding, Competitive immunology, Cell Line, Transformed, Chromatography, High Pressure Liquid methods, Electrophoresis, Gel, Two-Dimensional, Humans, Hybridomas, Molecular Sequence Data, Protein Binding immunology, HLA-DR2 Antigen immunology, Myelin Basic Protein immunology
Abstract: Affinity-purified major histocompatibility complex (MHC) class II molecules are known to bind antigenic peptides in vitro. The percentage of MHC class II molecules occupied with such peptides is usually very low and varies significantly depending upon the sequence and size of a given antigenic peptide. The present study describes a method by which complete saturation of affinity-purified MHC class II with antigenic peptide can be achieved by simply incubating purified MHC class II molecules at neutral pH in the presence of several 100-fold molar excess of antigenic peptide. Complexes of human HLA-DR2 and a peptide analog from human myelin basic protein MBP (83-102)Y83 were selected for this study. The on-rate kinetic results showed saturation of MHC class II occupancy at 300-500-fold molar excess peptide concentrations. The specificity of the MBP (83-102)Y83 peptide binding to HLA-DR2 at higher peptide concentration was demonstrated by incubating an equivalent amount of another epitope from myelin basic protein [MBP (1-14) peptide] as well as by competitive binding assays. The quantitation of bound peptide was carried out using biotinylated-MBP (83-102)Y83 peptide which showed 100-125% occupancy of HLA-DR2 with a recovery of 100%. The presence of a single peptide entity in purified complexes was confirmed by reverse-phase narrowbore HPLC analysis of the acid extracted supernatant and by mass spectrometry analysis. Two-dimensional gel electrophoresis (IEF/SDS) of purified HLA-DR2 and DR2.MBP (83-102)Y83 complexes showed the absence of various endogenous polypeptides in 100% loaded complexes. These results demonstrate that higher peptide concentrations can be useful in generating MHC class II-peptide complexes of defined composition. Such complexes of MHC class II occupied with a single peptide may have significant clinical relevance for antigen-specific therapy of various autoimmune diseases and may provide better understanding of MHC-peptide-TCR interactions.
Published: 1994
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30. The stabilization of a human IgM monoclonal antibody with poly(vinylpyrrolidone).

Author: Gombotz WR, Pankey SC, Phan D, Drager R, Donaldson K, Antonsen KP, Hoffman AS, and Raff HV
Subjects: Calorimetry, Differential Scanning, Chromatography, High Pressure Liquid, Drug Stability, Enzyme-Linked Immunosorbent Assay, Excipients, Hot Temperature, Light, Molecular Weight, Scattering, Radiation, Antibodies, Monoclonal chemistry, Immunoglobulin M chemistry, Povidone chemistry
Abstract: An IgM anti-group B Streptococcus monoclonal antibody (4B9) was found to undergo irreversible heat-induced aggregation at 50 degrees C. A variety of excipients was tested for their ability to inhibit antibody aggregation. The amount of 4B9 aggregation, which was determined by analysis on a size-exclusion HPLC, was significantly reduced in the presence of low concentrations [between 0.1 and 1.0% (w/v)] of poly(vinylpyrrolidone) (PVP) molecules ranging in molecular weight from 10 to 40 kDa. When the PVP concentration was greater than 1.0%, antibody aggregation was enhanced, and with the highest molecular weight PVP, antibody precipitation occurred. HPLC was used to show that more PVP was associated with the 4B9 at 50 degrees C than at 25 degrees C. Differential scanning calorimetry revealed that PVP concentrations greater than 2.0% decreased the antibody thermal transition temperature. Enzyme-linked immunosorbent assays were used to assess the effects of PVP on the antigen binding capacity of 4B9 and on 4B9 quantitation. At 4 degrees C, PVP solutions of up to 5.0% had no effect on either 4B9 quantitation or antigen binding. At 50 degrees C, however, less 4B9 was detected in the 5.0% PVP solution. The heat stabilization of the 4B9 antibody by low concentrations of PVP can be explained by a weak binding of PVP to the native protein. The PVP may sterically interfere with protein-protein interactions, thus reducing aggregation. Higher concentrations of PVP lead to protein aggregation and precipitation, probably by a volume-exclusion mechanism.(ABSTRACT TRUNCATED AT 250 WORDS)
Published: 1994
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31. Uptake pathways for amino acids in mouse intestine.

Author: Karasov W, Solberg D, Carter S, Hughes M, Phan D, Zollman F, and Diamond J
Subjects: Aminoisobutyric Acids metabolism, Animals, Aspartic Acid metabolism, Binding, Competitive, Biological Transport drug effects, Jejunum metabolism, Kinetics, Leucine metabolism, Lysine metabolism, Male, Methionine metabolism, Mice, Proline metabolism, Sodium pharmacology, Amino Acids metabolism, Intestinal Absorption drug effects
Abstract: This paper characterizes amino acid (AA) uptake pathways in an everted-sleeve preparation of mouse jejunum. AA uptake is linear with time for 2-4 min, depending on the particular AA and its uptake rate. Escape of tracer to the serosal surface is still negligible at these times. Errors due to metabolism of labeled AAs to volatile products can be minimized by using 14C- rather than 3H-labeled AAs and by not drying tissues before counting. The dependence of AA uptake on concentration shows saturable kinetics, with apparent Km values in the range 1-4 mM. By 25 or 50 mM an uptake plateau is reached for leucine, lysine, methionine, and methylaminoisobutyric acid but not for aspartic acid, histidine, or proline. Proline kinetics are the result of a saturable Na+-dependent component, a linear diffusional component, and possibly a small saturable Na+-independent component. The Na+-dependent component of uptake for six AAs averages 83% of the total at 0.01 mM and 54% at 25 or 50 mM. Leucine and D-glucose exhibit modest (32%) cross-inhibition of Na+-dependent uptake. For the same six AAs we determined the percent inhibition of both the Na+-dependent and the Na+-independent components by the other AAs. These results suggest the presence of at least five or six AA uptake pathways in mouse jejunum: distinct Na+-dependent pathways for acidic, basic, and neutral AAs and for imino acids; a shared Na+-independent pathway for basic and neutral AAs; and possibly a Na+-independent pathway for acidic AAs. Comparisons of AA uptake pathways in mouse, rabbit, and rat intestine reveal many similarities but also some differences.
Published: 1986
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32. Human heterozygosity: a new estimate.

Author: McConkey EH, Taylor BJ, and Phan D
Subjects: Black People, Humans, Isoelectric Point, Molecular Weight, White People, Heterozygote, Polymorphism, Genetic, Proteins genetics
Abstract: Several hundred polypeptides from four human diploid fibroblast cell lines were compared by high-resolution two-dimensional polyacrylamide gel electrophoresis and double-label autoradiography under conditions where allelic products that differ by a single charged amino acid would be distinguished. The average heterozygosity represented by this set of gene products appears to be less than 1% for changes involving charged amino acids.
Published: 1979
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33. [Effects produced in vitro and in vivo on the migration of rat polymorphonuclear leukocytes by anti-inflammatory drugs used in dentistry].

Author: Phan Huy D, Roch-Arveiller M, Muntaner O, and Giroud JP
Subjects: Animals, Aspirin pharmacology, Cell Migration Inhibition, Chemotaxis, Leukocyte drug effects, Dexamethasone pharmacology, Indomethacin pharmacology, Niflumic Acid pharmacology, Rats, Rats, Inbred Strains, Anti-Inflammatory Agents pharmacology, Neutrophils drug effects
Abstract: The effects produced in vivo and in vitro by indometacin, niflumic acid, acetylsalicylic acid and dexamethasone have been studied on rat polymorphonuclear leucocyte migration with the Boyden chamber technique (formyl - methionyl - leucyl - phenylalanine was the chemoattractant). Excepting acetylsalicylic acid, the drugs tested determined an inhibiting effect on leucocyte migration investigated by four experimental approaches. These substances exerted a direct effect and modified the chemotactic reactivity towards the chemotactic peptide after incubation in normal or inflammatory sera. They impeded the action of an antichemotactic factor released in sera during acute inflammatory reaction.
Published: 1982

34. Digestive physiology is a determinant of foraging bout frequency in hummingbirds.

Author: Diamond JM, Karasov WH, Phan D, and Carpenter FL
Subjects: Animals, Behavior, Animal physiology, Biological Transport, Digestion, Energy Metabolism, Feeding Behavior physiology, Gastrointestinal Motility, Glucose metabolism, Proline metabolism, Birds physiology
Abstract: Hummingbirds are among the smallest endothermic vertebrates. Because they forage by energetically costly hovering, and because weight-specific basal metabolic rates increase with decreasing body size, their basal and active metabolic rates are among the highest recorded. Hummingbirds fuel these metabolic requirements mainly with highly concentrated sugar in nectar, which they extract rapidly and efficiently by an unknown mechanism. It is especially puzzling that, despite their high energy requirements, hummingbirds spend only approximately 20% of their waking hours feeding, but 75% perched and apparently doing nothing. Here we report the first measurement of nutrient absorption by hummingbird intestine and present a new method for measuring crop-emptying times. We find that hummingbird intestine has the highest active glucose transport rate and lowest passive glucose permeability reported for any vertebrate. Crop-emptying time may limit feeding-bout frequency and could largely account for the time spent perched.
Published: 1986
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35. Weaning of premature infants from the incubator to an open crib.

Author: Sutter TW, Phan D, Pierchala CE, and Rishel W
Subjects: Body Weight, Hot Temperature, Humans, Infant, Newborn, Prospective Studies, Random Allocation, Incubators, Infant, Infant, Premature physiology
Abstract: Thirty pairs of healthy, growing preterm infants were included in this randomized prospective study comparing thermal weaning at 1700 g with that at 1800 g. Based on an intention-to-treat analysis, infants weaned at 1700 g were discharged 1.1 days sooner than those weaned at 1800 g. However, this result was not statistically significant (p = 0.13). On the other hand, differences are apparent between treatments in some strata based on birth weight (p = 0.0056). Evidence also existed that time from entry (at 1500 g) to discharge depended on birth weight stratum (p = 0.010). No infant in either group lost weight after successful weaning, and mean 24-hour weight gains were similar for both groups. Two infants were weaned at 1800 g requiring return to the incubator due to hypothermia, and four infants weaned at 1700 g likewise requiring return to the incubator. The number weaned at 1700 g who had birth weight of 1000 g or less and who developed hypothermia appeared substantial (three of six such infants). Thus, it appears that thermal weaning at 1700 g may be safe and effective only for prematures with birth weight above 1000 g. Additional study appears needed.
Published: 1988

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35 results on '"D. D. Phan"'

1. High deuteron and neutron yields from the interaction of a petawatt laser with a cryogenic deuterium jet

2. Seasonal variation of multiple-muon cosmic ray air showers observed in the NOvA detector on the surface

3. Search for Active-Sterile Antineutrino Mixing Using Neutral-Current Interactions with the NOvA Experiment

4. Improved Constraints on Sterile Neutrino Mixing from Disappearance Searches in the MINOS, MINOS+ , Daya Bay, and Bugey-3 Experiments

5. Precision Constraints for Three-Flavor Neutrino Oscillations from the Full MINOS+ and MINOS Dataset

6. First measurement of neutrino oscillation parameters using neutrinos and antineutrinos by NOvA

7. Search for sterile neutrinos in MINOS and MINOS+ using a two-detector fit

8. Miniature Antenna for IoT Devices Using LoRa Technology

9. A search for flavor-changing non-standard neutrino interactions using $ν_{e}$ appearance in MINOS

10. Measurement of singleπ0production by coherent neutral-currentνFe interactions in the MINOS Near Detector

11. A search for sterile neutrinos mixing with muon neutrinos in MINOS

12. Limits on Active to Sterile Neutrino Oscillations from Disappearance Searches in the MINOS, Daya Bay, and Bugey-3 Experiments

13. Measurement of the Multiple-Muon Charge Ratio in the MINOS Far Detector

14. Search for Sterile Neutrinos Mixing with Muon Neutrinos in MINOS

15. Measurement of the multiple-muon charge ratio in the MINOS Far Detector

16. Measurement of single pi(0) production by coherent neutral-current nu Fe interactions in the MINOS Near Detector

17. Detecting Induced p±ip Pairing at the Al-InAs Interface with a Quantum Microwave Circuit.

18. Point-of-care Hepatitis C virus testing and linkage to treatment in an Australian inner-city emergency department.

19. The influence of sagittal spinal deformity on anteversion of the acetabular component in total hip arthroplasty.

20. [Early detection of smoking related chronic obstructive pulmonary disease in Vietnam].

21. Arabinoxylan-lipid-based edible films and coatings. 3. Influence of drying temperature on film structure and functional properties.

22. Arabinoxylan-lipids-based edible films and coatings. 2. Influence of sucroester nature on the emulsion structure and film properties.

23. Androgen regulation of the cell-cell adhesion molecule-1 (Ceacam1) gene.

24. Differences in tissue-specific and embryonic expression of mouse Ceacam1 and Ceacam2 genes.

25. Purification and characterization of human cell--cell adhesion molecule 1 (C-CAM1) expressed in insect cells.

26. The cytoplasmic domain of C-CAM1 tumor suppressor is necessary and sufficient for suppressing the tumorigenicity of prostate cancer cells.

27. [Bloody nipple discharge in infants and young children].

28. pH dependent binding of high and low affinity myelin basic protein peptides to purified HLA-DR2.

29. Antigenic peptide binding to MHC class II molecules at increased peptide concentrations.

30. The stabilization of a human IgM monoclonal antibody with poly(vinylpyrrolidone).

31. Uptake pathways for amino acids in mouse intestine.

32. Human heterozygosity: a new estimate.

33. [Effects produced in vitro and in vivo on the migration of rat polymorphonuclear leukocytes by anti-inflammatory drugs used in dentistry].

34. Digestive physiology is a determinant of foraging bout frequency in hummingbirds.

35. Weaning of premature infants from the incubator to an open crib.

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35 results on '"D. D. Phan"'

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