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Objectives: Document initial outcomes of balloon kyphoplasty., Design: Retrospective analysis of the first 52 patients with 82 painful vertebral body compression fractures secondary to osteoporosis treated at our institution., Setting: Operation on subacute painful fractures with office follow-up., Patients/participants: First 82 fractures in 52 patients treated. All patients had failed nonoperative treatment and had magnetic resonance imaging scans documenting edematous changes of the vertebral body. Forty-nine out of 52 patients presented for follow-up at an average of 37 weeks., Intervention: Minimally invasive balloon reduction via bilateral transpedicular or extrapedicular approaches followed by polymethyl methacrylate fixation., Main Outcome Measures: Vertebral body height, Cobb angle, visual analogue pain scale, Roland-Morris Disability Survey, and complication rate., Results: Mean length of follow-up was 9 months (37 weeks, range 4-99 weeks); improved height 4.6 and 3.9 mm in the anterior and medial columns, respectively (P > 0.05); Cobb angle increased 14% (P < 0.05), visual analogue pain scale score improved 7 points (P < 0.05); Roland-Morris Disability Survey improved 11 points (P < 0.05); no adverse medical or procedural complications; 9.8% cement leakage rate., Conclusion: Balloon kyphoplasty safely improves vertebral body height and patient quality of life.

Study Design: Descriptive., Objectives: To document a rare complication involving the use of a wound drain after cervical laminectomy., Summary of the Background Data: No previous reports describe spinal cord compression by a surgical drain resulting in a neurologic deficit. Most texts recommend the use of a drain following this procedure., Methods: An 80-year-old female underwent cervical laminectomy for myelopathy with initial improvement in symptoms. Approximately 6 hours following surgery, she developed acute onset of quadriparesis when repositioning in bed. Magnetic resonance imaging revealed cord compression by the surgical drain, which was immediately removed., Results: The patient experienced partial improvement of the neurologic deficit. At 18-month follow-up, left handed weakness, left leg spasticity, and neurogenic bladder persist., Conclusion: The development of neurologic deficits due to compression by a surgical drain can occur. This complication might be avoided by approximating the neck musculature before placement of the drain and closure of the fascia.

Background: Meniscal bearing total knee replacements were developed to decrease the contact stresses on polyethylene and to reduce polyethylene wear. The kinematics of meniscal bearing knee replacements is poorly understood. The present study was designed to evaluate, with radiographic analyses, the motion of the meniscal bearings and the femoral rollback of the Low Contact Stress meniscal bearing knee replacement during knee flexion., Methods: Eighty-one Low Contact Stress meniscal bearing total knee replacements in seventy-six male patients were assessed on fluoroscopically centered lateral radiographs made with the knee in full extension and in full flexion at an average of six years (range, twenty-four to 147 months) after the operation. The distance and direction of motion of the meniscal bearings and the center contact position of the femoral condyles were measured. Knee evaluations were performed with use of the Knee Society rating system., Results: The average range of motion of the knees, measured on lateral radiographs, was 90 degrees (range, 45 degrees to 136 degrees). As they moved from terminal extension to terminal flexion, thirty-nine knees (48%) exhibited anterior motion of both bearings and sixteen (20%) demonstrated posterior motion of both bearings. Ten knees (12%) had reciprocal motion of the two bearings (one bearing moving anteriorly and one bearing moving posteriorly) with flexion, nine knees (11%) had motion of only one bearing, and seven knees (9%) had no motion of either bearing. When moving from full extension to full flexion, eighteen knees (22%) demonstrated femoral rollback, six knees (7%) showed no change in the position of femoral contact, and fifty-seven knees (70%) exhibited anterior sliding of the femoral condyles. Flexion of the knees demonstrating femoral rollback averaged 104 degrees (range, 76 degrees to 128 degrees), and flexion of the knees demonstrating anterior sliding averaged 94 degrees (range, 45 degrees to 125 degrees). The difference was significant (p = 0.03). According to the Knee Society rating system, the average clinical score for the entire group was 76 points (range, 27 to 100 points) and the average functional score for the entire group was 72 points (range, 30 to 100 points). The average clinical score was 79 points (range, 27 to 98 points) for the knees that exhibited anterior sliding of the femoral condyles and 87 points (range, 52 to 100 points) for those exhibiting femoral rollback (p = 0.09). The average functional scores were 64 points (range, 30 to 100 points) and 72 points (range, 45 to 100 points), respectively (p = 0.15)., Conclusions: Radiographic analysis of meniscal bearing total knee replacements demonstrated an average anterior motion of both the medial and the lateral meniscal bearing of 4.7 mm (range, 1 to 14 mm) in thirty-nine knees (48%) as they moved from terminal extension to terminal flexion. Sixty-three knees (78%) demonstrated no femoral rollback as they were flexed. Knees with anterior sliding of the condyles had a significantly smaller average range of flexion (p = 0.03) and a lower average Knee Society score than did knees demonstrating femoral rollback. We believe that lack of rollback indicates a functional insufficiency of the posterior cruciate ligament.

A model was established in 39 dogs to investigate the growth factor modulation of regenerate bone in distraction osteogenesis. A segment of the diaphysis of the radius was resected unilaterally. An osteotomy was made proximal to the segmental defect to create a transport segment. A monolateral external fixator was applied. After a latency period, the segment was transported across the defect. One week after the transport assembly contacted the distal pin clamp, an ipsilateral osteotomy of the proximal ulna was performed. In 20 dogs, transforming growth factor-beta was injected into the regenerate bone halfway through the transport period. Four dogs were sacrificed before docking, when the regenerate bone was still immature. In specimens harvested halfway through the transport period, evidence was found of intramembranous ossification during distraction. In specimens harvested after the transport assembly contacted the distal pin clamp, evidence was found that the mature regenerate formed by endochondral ossification. Therefore, a combined mechanism of ossification is proposed for this segmental defect model that includes mechanical stimulus for bone differentiation. The one-time administration of transforming growth factor-beta retarded the formation of a stable, united regenerate. It is concluded that transforming growth factor-beta caused an effect opposite to that which was desired.