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We investigate the extreme X-ray variability of a z = 1.608 active galactic nucleus in the 7 Ms Chandra Deep Field-South (XID 403), which showed two significant X-ray brightening events. In the first event, XID 403 brightened by a factor of $>2.5$ in $\lesssim6.1$ rest-frame days in the observed-frame 0.5-5 keV band. The event lasted for $\approx5.0\textrm{-}7.3$ days, and then XID 403 dimmed by a factor of $>6.0$ in $\lesssim6.1$ days. After $\approx1.1\textrm{-}2.5$ years in the rest frame (including long observational gaps), it brightened again with the 0.5-5 keV flux increasing by a factor of $>12.6$. The second event lasted over 251 days and the source remained bright until the end of the 7 Ms exposure. The spectrum is a steep power law (photon index $Γ=2.8\pm0.3$) without obscuration during the second outburst, and the rest-frame 2-10 keV luminosity reaches $1.5^{+0.8}_{-0.5}\times10^{43}$ erg s$^{-1}$; there is no significant spectral evolution within this epoch. The infrared-to-UV spectral energy distribution of XID 403 is dominated by the host galaxy. There is no significant optical/UV variability and $R$-band (rest-frame $\approx2500$ $\unicode{xC5}$) brightening contemporaneous with the X-ray brightening. The extreme X-ray variability is likely due to two X-ray unveiling events, where the line of sight to the corona is no longer shielded by high-density gas clumps in a small-scale dust-free absorber. XID 403 is probably a high-redshift analog of local narrow-line Seyfert 1 galaxies, and the X-ray absorber is a powerful accretion-disk wind. On the other hand, we cannot exclude the possibility that XID 403 is an unusual candidate for tidal disruption events., 23 pages, 9 figures, accepted for publication in ApJ

The present study is designed to study processes occurring during the electrical discharge machining (EDM) of tool steels, the influence of orbiting electrode motion on its accuracy, as well as to justify the application of individual orbiting trajectories and implement these data into production. To that end, a trajectory program was written in machine codes for a Mitsubishi EA-28 die-sinking electrical discharge machine using the CIMCO EDIT software package. Also, a prototype punch and ejector of the blanking die were produced and measured. The standard modes of Mitsubishi EA-28 were used to carry out machining in Blasospark GT 250 dielectric fluid to a roughness of Ra 0.6 in 9 passes. The experiments revealed the influence of electrode geometry on the machining of sharp corners, i.e., the formation of unwanted radii on the workpiece. However, this phenomenon is not observed when the corners are drilled with small diameter holes (0.4–0.6 mm). Depending on the machining process along the inner or outer trajectory, inverse electrode motion is also observed. The production part (punch of the blanking die) was machined using a new orbit adjusted to the geometry of the product. The part was found to be consistent with the requirements and the engineering drawing, thus allowing the assembled die to enter the main production. The results of the performed tests, as well as the study of domestic and foreign experience, were used to develop recommendations on the use of individual orbits in the EDM of tool steels, hard alloys, and other hard-to-machine conductive materials. The method of orbiting motion along a particular trajectory was implemented at Cheboksary Electrical Apparatus Plant (Cheboksary).

Este artigo apresenta um estudo teórico sobre parâmetros de convexidade em grafos com uma aplicação na área de Sistema de Recomendação. O objetivo é modelar a propagação de uma recomendação em uma rede de modo que um conjunto mínimo de usuários possa recomendar itens aos demais usuários associados com o máximo de aceitação e menor perda de informação repassada.

Physically realized electron gas systems usually reside in either the quantum non-degenerate or fully degenerate limit, where the average de Broglie wavelength of the thermal electrons becomes comparable with the interparticle distance between electrons. A few systems, such as young brown dwarfs and the cold dense fuels created in imploded cryogenic capsules at the National Ignition Facility, lie between these two limits and are partially degenerate. The National Ignition Facility has the unique capability of varying the electron quantum degeneracy by adjusting the laser drive used to implode the capsules. This allows experimental studies of the effects of the degeneracy level on plasma transport properties. By measuring rare nuclear reactions in these cold dense fuels, we show that the electron stopping power, which is the rate of energy loss per unit distance travelled by a charged particle, changes with increasing electron density. We observe a quantum-induced shift in the peak of the stopping power using diagnostics that measure above and below this peak. The observed changes in the stopping power are shown to be unique to the transition region between non-degenerate and degenerate plasmas. Our results support the screening models applied to partially degenerate astrophysical systems such as young brown dwarfs. Transitions between non-degenerate and degenerate plasma are observed in laser-driven implosions of cryogenic capsules at the National Ignition Facility. The observed partially degenerate regime is relevant to the physics of young brown dwarfs.

Context. Feedback from active galactic nuclei (AGNs) in general seems to play an important role in the evolution of galaxies, although the impact of AGN winds on their host galaxies is still unknown in the absence of a detailed analysis. Aims. We aim to analyse the kinematics of a sample of 170 AGN host galaxies as compared to those of a matched control sample of non-active galaxies from the MaNGA survey in order to characterise and estimate the extents of the narrow-line region (NLR) and of the kinematically disturbed region (KDR) by the AGN. Methods. We defined the observed NLR radius (rNLR, o) as the farthest distance from the nucleus within which both [O III]/Hβ and [N II]/Hα ratios fall in the AGN region of the BPT diagram, and the Hα equivalent width was required to be larger than 3.0 Å. The extent of the KDR (rKDR, o) is defined as the distance from the nucleus within which the AGN host galaxies show a more disturbed gas kinematics than the control galaxies. Results. The AGN [O III]λ5007 luminosity ranges from 1039 to 1041 erg s−1, and the kinematics derived from the [O III] line profiles reveal that, on average, the most luminous AGNs (L[O III] > 3.8 × 1040 erg s−1) possess higher residual differences between the gaseous and stellar velocities and velocitie dispersions than their control galaxies in all the radial bins. Spatially resolved NLRs and KDRs were found in 55 and 46 AGN host galaxies, with corrected radii 0.2, This study was funded in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) – Finance Code 001, Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Fundação de Amparo à pesquisa do Estado do RS (FAPERGS). ADM acknowledges financial support from the Spanish MCIU grant PID2019-106027GB-C41 and from the State Agency for Research of the Spanish MCIU through the “Center of Excellence Severo Ochoa” award for the Instituto de Astrofísica de Andalucía (SEV-2017-0709). ADM also acknowledges the support of the INPhINIT fellowship form “la Caixa” Foundation (ID 100010434), under the fellowship code LCF/BQ/DI19/11730018. SDSS is managed by the Astrophysical Research Consortium for the Participating Institutions of the SDSS Collaboration including the Brazilian Participation Group, the Carnegie Institution for Science, Carnegie Mellon University, the Chilean Participation Group, the French Participation Group, Harvard-Smithsonian Center for Astrophysics, Instituto de Astrofisica de Canarias, The Johns Hopkins University, Kavli Institute for the Physics and Mathematics of the Universe (IPMU)/University of Tokyo, the Korean Participation Group, Lawrence Berkeley National Laboratory, Leibniz Institut für Astrophysik Potsdam (AIP), Max-Planck-Institut für Astronomie (MPIA Heidelberg), Max-Planck-Institut für Astrophysik (MPA Garching), Max-Planck-Institut für Extraterrestrische Physik (MPE), National Astronomical Observatories of China, New Mexico State University, New York University, University of Notre Dame, Observatório Nacional/MCTI, The Ohio State University, Pennsylvania State University, Shanghai Astronomical Observatory, United Kingdom Participation Group, Universidad Nacional Autónoma de México, University of Arizona, University of Colorado Boulder, University of Oxford, University of Portsmouth, University of Utah, University of Virginia, University of Washington, University of Wisconsin, Vanderbilt University, and Yale University.

We present the first near-IR spectroscopy and joint analyses of multi-wavelength observations for SDSS J082747.14+425241.1, a dust-reddened, weak broad emission-line quasar (WLQ) undergoing a remarkable broad absorption line (BAL) transformation. The systemic redshift is more precisely measured to be $z=2.070\pm0.001$ using H$\beta$ compared to $z=2.040\pm0.003$ using \mgii\ from the literature, signifying an extreme \mgii\ blueshift of $2140\pm530$ \kms\ relative to H$\beta$. Using the H$\beta$-based single-epoch scaling relation with a systematic uncertainty of 0.3 dex, its black hole (BH) mass and Eddington ratio are estimated to be $M_{\rm BH}\sim6.1\times10^8M_\odot$ and $\lambda_{\rm Edd}\sim0.71$, indicative of being in a rapidly accreting phase. Our investigations confirm the WLQ nature and the LoBAL$\rightarrow$HiBAL transformation, along with a factor of 2 increase in the \mgii+\feii\ emission strength and a decrease of 0.1 in $E(B-V)$ over two decades. The kinetic power of this LoBAL wind at $R\sim$15 pc from its BH is estimated to be $\sim$43\% of the Eddington luminosity, sufficient for quasar feedback upon its host galaxy albeit with an order-of-magnitude uncertainty. This quasar provides a clear example of the long-sought scenario where LoBAL quasars are surrounded by dust cocoons, and wide-angle nuclear winds play a key role in the transition for red quasars evolving into the commonly seen blue quasars., Comment: 11 pages, 6 figures, accepted for publication in ApJ

Whole plant chlorophyll fluorescence imaging is a powerful tool for non-destructive analysis of photosynthesis. Analysis of such images requires software that is able to process and calculate photo...

We present accretion-disk structure measurements from UV-optical reverberation mapping observations of a sample of eight quasars at 0.24, Comment: 24 pages, 13 figures, figure 5 (7 images) is available as a figure set. Accepted for publication in ApJ

Data from the SPectroscopic IDentification of ERosita Sources (SPIDERS) are searched for a detection of the gravitational redshifting of light from $\sim\!20\,000$ galaxies in $\sim\!2500$ galaxy clusters using three definitions of the cluster centre: its Brightest Cluster Galaxy (BCG), the redMaPPer identified Central Galaxy (CG), or the peak of X-ray emission. Distributions of velocity offsets between galaxies and their host cluster's centre, found using observed redshifts, are created. The quantity $\hat{\Delta}$, the average of the radial velocity difference between the cluster members and the cluster systemic velocity, reveals information on the size of a combination of effects on the observed redshift, dominated by gravitational redshifting. The change of $\hat{\Delta}$ with radial distance is predicted for SPIDERS galaxies in General Relativity (GR), and $f(R)$ gravity, and compared to the observations. The values of $\hat{\Delta}=-13.5\pm4.7$ km s$^{-1}$, $\hat{\Delta}=-12.5\pm5.1$ km s$^{-1}$, and $\hat{\Delta}=-18.6\pm4.8$ km s$^{-1}$ for the BCG, X-ray and CG cases respectively broadly agree with the literature. There is no significant preference of one gravity theory over another, but all cases give a clear detection ($>2.5\sigma$) of $\hat{\Delta}$. The BCG centroid is deemed to be the most robust method in this analysis, due to no well defined central redshift when using an X-ray centroid, and CGs identified by redMaPPer with no associated spectroscopic redshift. For future gravitational redshift studies, an order of magnitude more galaxies, $\sim\!500\,000$, will be required-a possible feat with the forthcoming Vera C. Rubin Observatory, Euclid and eROSITA., Comment: Accepted for publication in MNRAS. 11 pages, 10 figures

We present the results of a pilot Hubble Space Telescope (HST) imaging study of the host galaxies of ten quasars from the Sloan Digital Sky Survey Reverberation Mapping (SDSS-RM) project. Probing more than an order of magnitude in BH and stellar masses, our sample is the first statistical sample to study the BH-host correlations beyond z>0.3 with reliable BH masses from reverberation mapping rather than from single-epoch spectroscopy. We perform image decomposition in two HST bands (UVIS-F606W and IR-F110W) to measure host colors and estimate stellar masses using empirical relations between broad-band colors and the mass-to-light ratio. The stellar masses of our targets are mostly dominated by a bulge component. The BH masses and stellar masses of our sample broadly follow the same correlations found for local RM AGN and quiescent bulge-dominant galaxies, with no strong evidence of evolution in the M_BH-M_*,bulge relation to z~0.6. We further compare the host light fraction from HST imaging decomposition to that estimated from spectral decomposition. We found a good correlation between the host fractions derived with both methods. However, the host fraction derived from spectral decomposition is systematically smaller than that from imaging decomposition by ~30%, indicating different systematics in both approaches. This study paves the way for upcoming more ambitious host galaxy studies of quasars with direct RM-based BH masses at high redshift., Comment: 19 pages, 8 figures, submitted to ApJ

Results from a few decades of reverberation mapping (RM) studies have revealed a correlation between the radius of the broad-line emitting region (BLR) and the continuum luminosity of active galactic nuclei. This "radius-luminosity" relation enables survey-scale black-hole mass estimates across cosmic time, using relatively inexpensive single-epoch spectroscopy, rather than intensive RM time monitoring. However, recent results from newer reverberation mapping campaigns challenge this widely used paradigm, reporting quasar BLR sizes that differ significantly from the previously established radius-luminosity relation. Using simulations of the radius--luminosity relation with the observational parameters of SDSS-RM, we find that this difference is not likely due to observational biases. Instead, it appears that previous RM samples were biased to a subset of quasar properties, and the broader parameter space occupied by the SDSS-RM quasar sample has a genuinely wider range of BLR sizes. We examine the correlation between the deviations from the radius-luminosity relation and several quasar parameters; the most significant correlations indicate that the deviations depend on UV/optical SED and the relative amount of ionizing radiation. Our results indicate that single-epoch black-hole mass estimates that do not account for the diversity of quasars in the radius-luminosity relation could be overestimated by an average of ~0.3 dex., Comment: 11 pages, 12 figures. Submitted to ApJ. Current version includes revisions after referee report

Neutron spectra from secondary ^{3}H(d,n)α reactions produced by an implosion of a deuterium-gas capsule at the National Ignition Facility have been measured with order-of-magnitude improvements in statistics and resolution over past experiments. These new data and their sensitivity to the energy loss of fast tritons emitted from thermal ^{2}H(d,p)^{3}H reactions enable the first statistically significant investigation of charged-particle stopping via the emitted neutron spectrum. Radiation-hydrodynamic simulations, constrained to match a number of observables from the implosion, were used to predict the neutron spectra while employing two different energy loss models. This analysis represents the first test of stopping models under inertial confinement fusion conditions, covering plasma temperatures of k_{B}T≈1-4 keV and particle densities of n≈(12-2)×10^{24} cm^{-3}. Under these conditions, we find significant deviations of our data from a theory employing classical collisions whereas the theory including quantum diffraction agrees with our data.

The National Ignition Facility (NIF) provides the opportunity to study nuclear reactions under controlled conditions at high temperatures and pressures at a level never before achieved. However, the timescale of the deuterium-tritium (DT) implosion is only a few nanoseconds, making data collection and diagnostics very challenging. One method that has been proposed for obtaining additional information about the conditions of the implosion is to activate a dopant material using the $\ensuremath{\alpha}$ particles produced from the DT fuel as a diagnostic. The yield of the activated material can give a measure of the mixing that occurs in the capsule. One of the reactions that has been proposed is $^{10}\mathrm{B}(\ensuremath{\alpha},n)\phantom{\rule{0.16em}{0ex}}^{13}\mathrm{N}$ as it produces a radioactive reactant product with a convenient half-life of $\ensuremath{\approx}10\phantom{\rule{0.16em}{0ex}}\mathrm{min}$. Although this reaction has several advantages for the application at hand, it has not seen much study in the present literature, resulting in large uncertainties in the cross section. Furthermore, for the current application, the cross section must be well characterized. With this motivation, the $^{10}\mathrm{B}(\ensuremath{\alpha},n)\phantom{\rule{0.16em}{0ex}}^{13}\mathrm{N}$ cross section has been remeasured for $2.2l{E}_{\ensuremath{\alpha}}l4.9\phantom{\rule{0.28em}{0ex}}\mathrm{MeV}$ with the angle-integrated ground-state cross section reported for the first time. The present results, combined with previous measurements, allow for a determination of the cross section to a significantly higher degree of accuracy and precision than obtained previously and are shown to be consistent with thick-target measurements. Preliminary calculations are performed to test the feasibility of this reaction as a diagnostic for a NIF implosion.

We report on an X-ray and optical/UV study of eight Broad Absorption Line (BAL) to non-BAL transforming quasars at $z\,\approx\,$1.7-2.2 over 0.29-4.95 rest-frame years with at least three spectroscopic epochs for each quasar from the SDSS, BOSS, $Gemini$, and ARC 3.5-m telescopes. New $Chandra$ observations obtained for these objects show their values of $\alpha_{\rm ox}$ and $\Delta{\alpha}_{\rm ox}$, as well as their spectral energy distributions, are consistent with those of non-BAL quasars. Moreover, our targets have X-ray spectral shapes that are, on average, consistent with weakened absorption with an effective power-law photon index of $\Gamma_{\rm eff}\,=\,1.69^{+0.25}_{-0.25}$. The newer $Gemini$ and ARC 3.5-m spectra reveal that the BAL troughs have remained absent since the BOSS observations where the BAL disappearance was discovered. The X-ray and optical/UV results in tandem are consistent with at least the X-ray absorbing material moving out of the line-of-sight, leaving an X-ray unabsorbed non-BAL quasar. The UV absorber might have become more highly ionized (in a shielding-gas scenario) or also moved out of the line-of-sight (in a wind-clumping scenario)., Comment: 14 pages, 5 figures, Accepted for publication in MNRAS

We report on the discovery of a dramatic X-ray spectral variability event observed in a $z\sim 1$ broad line type-1 QSO. The XMM-Newton spectrum from the year 2000 is characterized by an unobscured power-law spectrum with photon index of $\Gamma\sim 2$, a column density of $N_{\mathrm{H}}\sim 5\times 10^{20}\,\mathrm{cm^{-2}}$, and no prominent reflection component. Five years later, Chandra captured the source in a heavily-obscured, reflection-dominated state. The observed X-ray spectral variability could be caused by a Compton-thick cloud with $N_{\mathrm{H}}\sim 2\times 10^{24}\,\mathrm{cm^{-2}}$ eclipsing the direct emission of the hot corona, implying an extreme $N_{\mathrm{H}}$ variation never before observed in a type-1 QSO. An alternative scenario is a corona that switched off in between the observations. In addition, both explanations require a significant change of the X-ray luminosity prior to the obscuration or fading of the corona and/or a change of the relative geometry of the source/reflector system. Dramatic X-ray spectral variability of this kind could be quite common in type-1 QSOs, considering the relatively few datasets in which such an event could have been identified. Our analysis implies that there may be a population of type-1 QSOs which are Compton-thick in the X-rays when observed at any given time., Comment: 7 pages, 4 figures, to be published in MNRAS

At the completion of the National Ignition Campaign (NIC), the National Ignition Facility (NIF) had about 36 different types of diagnostics. These were based on several decades of development on No...

We determined fission yields of xenon (133mXe, 135Xe, 135mXe, 137Xe, 138Xe, and 139Xe) resulting from 14 MeV neutron induced fission of depleted uranium at the National Ignition Facility. Measurements begin approximately 20 s after shot time, and yields have been determined for nuclides with half-lives as short as tens of seconds. We determined the relative independent yields of 133mXe, 135Xe, and 135mXe to significantly higher precision than previously reported. The relative fission yields of all nuclides are statistically indistinguishable from values reported by England and Rider (ENDF-349. LA-UR-94-3106, 1994), with exception of the cumulative yield of 139Xe. Considerable differences exist between our measured yields and the JEFF-3.1 database values.

In deep X-ray surveys, active galactic nuclei (AGNs) with a broad range of luminosities have been identified. However, cosmologically distant low-luminosity AGN (LLAGN, $L_{\mathrm{X}} \lesssim 10^{42}$ erg s$^{-1}$) identification still poses a challenge due to significant contamination from host galaxies. Based on the 7 Ms Chandra Deep Field-South (CDF-S) survey, the longest timescale ($\sim 17$ years) deep X-ray survey to date, we utilize an X-ray variability selection technique to search for LLAGNs that remain unidentified among the CDF-S X-ray sources. We find 13 variable sources from 110 unclassified CDF-S X-ray sources. Except for one source which could be an ultraluminous X-ray source, the variability of the remaining 12 sources is most likely due to accreting supermassive black holes. These 12 AGN candidates have low intrinsic X-ray luminosities, with a median value of $7 \times10^{40}$ erg s$^{-1}$. They are generally not heavily obscured, with an average effective power-law photon index of 1.8. The fraction of variable AGNs in the CDF-S is independent of X-ray luminosity and is only restricted by the total number of observed net counts, confirming previous findings that X-ray variability is a near-ubiquitous property of AGNs over a wide range of luminosities. There is an anti-correlation between X-ray luminosity and variability amplitude for high-luminosity AGNs, but as the luminosity drops to $\lesssim 10^{42}$ erg s$^{-1}$, the variability amplitude no longer appears dependent on the luminosity. The entire observed luminosity-variability trend can be roughly reproduced by an empirical AGN variability model based on a broken power-law power spectral density function., Comment: 18 pages, 11 figures, accepted for publication in ApJ

STUDY QUESTION: What are the European trends and developments in ART and IUI in 2014 as compared to previous years? SUMMARY ANSWER: The 18th ESHRE report on ART shows a continuing expansion of both treatment numbers in Europe and more variability in treatment modalities resulting in a rising contribution to the birth rates in most participating countries. WHAT IS KNOWN ALREADY: Since 1997, ART data generated by national registries have been collected, analysed by the European IVF-monitoring (EIM) Consortium and reported in 17 manuscripts published in Human Reproduction. STUDY DESIGN, SIZE, DURATION: Continuous collection of European data by the EIM for ESHRE. The data for treatments performed in 2014 between 1 January and 31 December in 39 European countries were provided by national registries or on a voluntary basis by clinics or professional societies. PARTICIPANTS/MATERIALS, SETTING, METHODS: From 39 countries and 1279 institutions offering ART services, a total of 776 556 treatment cycles, involving 146 148 with IVF, 362 285 with ICSI, 192 027 with frozen embryo replacement (FER), 15 894 with PGT, 56 516 with egg donation (ED), 292 with IVM and 3404 with frozen oocyte replacement (FOR) were reported. European data on IUI using husband/partner's semen (IUI-H) and donor semen (IUI-D) were reported from 1364 institutions offering IUI in 26 countries and 21 countries, respectively. A total of 120 789 treatments with IUI-H and 49 163 treatments with IUI-D were included. MAIN RESULTS AND THE ROLE OF CHANCE: In 14 countries (17 in 2013), where all institutions contributed to their respective national registers, a total of 291 235 treatment cycles were performed in a population of ~208 million inhabitants, corresponding to 1925 cycles per million inhabitants (range: 423-2978 per million inhabitants). After treatment with IVF the clinical pregnancy rates (PR) per aspiration and per transfer were marginally higher in 2014 than in 2013, at 29.9 and 35.8% versus 29.6 and 34.5%, respectively. After treatment with ICSI the PR per aspiration and per transfer were also higher than those achieved in 2013 (28.4 and 35.0% versus 27.8 and 32.9%, respectively). After FER with own embryos the PR continued to rise, from 27.0% in 2013 to 27.6% in 2014. After ED a similar trend was observed with PR reaching 50.3% per fresh transfer (49.8% in 2013) and 48.7% for FOR (46.4% in 2013). The delivery rates (DR) after IUIremained stable at 8.5% after IUI-H (8.6% in 2013) and at 11.6% after IUI-D (11.1% in 2013). In IVF and ICSI together, 1, 2, 3 and ≥4 embryos were transferred in 34.9, 54.5, 9.9 and in 0.7% of all treatments, respectively (corresponding to 31.4%, 56.3, 11.5% and 1% in 2013). This evolution in embryo transfer strategy in both IVF and ICSI resulted in a singleton, twin and triplet DR of 82.5, 17.0 and 0.5%, respectively (compared to 82.0, 17.5 and 0.5%, respectively, in 2013). Treatments with FER in 2014 resulted in a twin and triplet DR of 12.4 and 0.3%, respectively (versus 12.5 and 0.3% in 2013). Twin and triplet DR after IUI were 9.5 and 0.3%, respectively, after IUI-H (in 2013:9.5 and 0.6%) and 7.7 and 0.3% after IUI-D (in 2013: 7.5 and 0.3%). LIMITATION, REASONS FOR CAUTION: The method of data collection and reporting varies among European countries. The EIM receives aggregated data from various countries with variable levels of completeness. Registries from a number of countries have failed to provide adequate data about the number of initiated cycles and deliveries. As long as incomplete data are provided, the results should be interpreted with caution. WIDER IMPLICATIONS OF THE FINDINGS: The 18th ESHRE report on ART shows a continuing expansion of treatment numbers in Europe. The number of treatments reported, the variability in treatment modalities and the rising contribution to the birth rates in most participating countries point towards the increasing impact of ART on reproduction in Europe. Being the largest data collection on ART, the report gives detailed information about ongoing developments in the field. © The Author(s) 2018. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved.

Summary Background: The upper limit of the natural decline in creatinine clearance is 1 ml/min/year. To define the loss of renal function, we started a long-term assessment of patients with ovarian cancer treated by whole abdominal irradiation (WAI) with preceding cisplatin chemotherapy (CDDP) and secondlook laparotomy (SLL). Patients and methods- We analyzed the creatinine clearance over time of 56 patients treated from 1982 to 1988 for ovarian cancer. Thirty-one of 56 patients had received WAI after their initial surgery, and 25 of 56 patients had undergone CDDP therapy followed by SLL, and then WAI after their initial surgery. Median follow-up was 99 months (7-156). Twenty of 56 patients accepted our invitation for additional assessment of tubular function, nine of the 31 patients without CDDP therapy and SLL, and 11 of the 25 patients with CDDP followed by SLL and WAI. Ten of twenty patients had received four to six cycles CDDP, 80 mg/m 2 /cycle, and one patient nine cycles. The median total dose for each kidney was 1450 cGy (480-1690). Results: The mean creatinine clearance decreased from 84 ml/min to 66 ml/min. Seventy-six percent of the 25 patients who had undergone CDDP therapy, SLL and WAI had declines of more than 1 ml/min/year, 64% of these patients of more than 2 ml/min/year. For the 31 patients who had received WAI after their initial surgery, the corresponding numbers were 71% and 55%, respectively. The tubular function of the 20 patients who had undergone the additional investigations was not impaired. Conclusion: The decline in renal function after WAI is more pronounced than in healthy subjects. The treatment with cisplatin and SLL prior to WAI does not seem to contribute to this loss of kidney function.

Library managers need current and accurate financial data to make critical resource allocation decisions. The implementation of library accounting functions on a microcomputer can aid in making both the accounting and the managerial functions more effective.

Mortality in swine herds is often associated with lameness, and trace minerals are implicated in maintaining integrity of skeletal tissues. The objectives of this study were to determine if prolific sows displayed evidence of trace mineral depletion with age and to determine the prevalence of osteochondrosis (OC) lesions. Reduced mineral concentrations with age would support recommendations for an increase in the amount of dietary minerals. Tissue samples were collected from 66 sows selected to represent a cross-sectional profile of a prolific herd fed diets with inorganic sources of trace minerals fortified at concentrations typically found in commercial diets. Females ranged from nulliparous (parity 0) to parity 7 with a lifetime average of 12.9 ± 0.5 pigs born alive per litter. Minerals were assessed in humerus, scapula, ovary, liver, and muscle (psoas major) tissues. Percent bone ash increased (P < 0.05) with parity from 64 to 66% but differed among bone sections. The Ca (39.0%) and P (18.9%) concentrations in bone ash were essentially constant in all sections and parities. Bone Cu, Fe, Mn, and Zn concentrations varied among sections, but differences due to parity (P < 0.05) were only detected in Fe. Bone Fe decreased from approximately 49 μg/g ash in parity 0 and 1 sows to approximately 29 μg/g ash in parity 7, likely reflecting loss of hemopoietic tissue with age. No evidence was detected in liver for depletion of trace minerals across parity; however, liver Cu and Zn concentrations tended to increase with age. Liver Mn concentrations varied with parity, but no consistent trend with parity was evident. Ovary Cu and Mn concentrations varied dramatically as a function of the reproductive status, but no evidence was detected for depletion with parity. Articular surfaces of the distal scapula and proximal and distal humerus were evaluated grossly for prevalence of OC; bones were then sectioned to evaluate lesions in subchondral bone and physis. Incidence of OC lesions on the articular-epiphyseal cartilage complex varied among bone sites, but differences across parities were not detected. In a subset of sows with subchondral bone lesions, the lesions appeared severe enough to contribute to clinical lameness, particularly in the distal humerus site. However, none of the sows exhibited lameness at slaughter. As no reductions in mineral concentrations with age were detected, recommendations to increase dietary mineral supplementation with age were not supported.

Baade's window (BW) is one of the most observed Galactic bulge fields in terms of chemical abundances. Due to its low and homogeneous interstellar absorption it is considered as a calibration field for Galactic bulge studies. In the era of large spectroscopic surveys, calibration fields such as BW are necessary to cross calibrate the stellar parameters and individual abundances of the APOGEE survey. We use the APOGEE BW stars to derive their metallicity distribution function (MDF) and individual abundances, for $\alpha$- and iron-peak elements of the APOGEE ASPCAP pipeline (DR13), as well as the age distribution for stars in BW. We determine the MDF of APOGEE stars in BW and find a remarkable agreement with that of the Gaia-ESO survey (GES). Both exhibit a clear bimodal distribution. We also find that the Mg-metallicity planes of both surveys agree well, except for the metal-rich part ([Fe/H] >0.1), where APOGEE finds systematically higher Mg abundances with respect to the GES. The ages based on the [C/N] ratio reveal a bimodal age distribution, with a major old population at 10 Gyr, with a decreasing tail towards younger stars. A comparison between APOGEE estimates and stellar parameters, and those determined by other sources reveals detectable systematic offsets, in particular for spectroscopic surface gravity estimates. In general, we find a good agreement between individual abundances of O, Na, Mg, Al, Si, K, Ca, Cr, Mn, Co, and Ni from APOGEE with that of literature values. We have shown that in general APOGEE data show a good agreement in terms of MDF and individual chemical abundances with respect to literature works. Using the [C/N] ration we found a significant fraction of young stars in BW which is in agreement with the model of Haywood et al. (2016)., Comment: 14 pages, 15 figure, accepted for Astronomy&Astrophysics

We present two wide-field catalogs of photometrically-selected emission line galaxies (ELGs) at z=0.8 covering about 2800 deg^2 over the south galactic cap. The catalogs were obtained using a Fisher discriminant technique described in a companion paper. The two catalogs differ by the imaging used to define the Fisher discriminant: the first catalog includes imaging from the Sloan Digital Sky Survey and the Wide-Field Infrared Survey Explorer, the second also includes information from the South Galactic Cap U-band Sky Survey (SCUSS). Containing respectively 560,045 and 615,601 objects, they represent the largest ELG catalogs available today and were designed for the ELG programme of the extended Baryon Oscillation Spectroscopic Survey (eBOSS). We study potential sources of systematic variation in the angular distribution of the selected ELGs due to fluctuations of the observational parameters. We model the influence of the observational parameters using a multivariate regression and implement a weighting scheme that allows effective removal of all of the systematic errors induced by the observational parameters. We show that fluctuations in the imaging zero-points of the photometric bands have minor impact on the angular distribution of objects in our catalogs. We compute the angular clustering of both catalogs and show that our weighting procedure effectively removes spurious clustering on large scales. We fit a model to the small scale angular clustering, showing that the selections have similar biases of 1.35/D_a(z) and 1.28/D_a(z). Both catalogs are publicly available., Accepted for publication in MNRAS. 16 pages, 12 figures

Journal of physics / Conference Series 875, 012008 (2017). doi:10.1088/1742-6596/875/2/012008, Published by IOP Publ., Bristol