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159 results on '"DʼAvolio A"'

46. Early virological failure with cabotegravir/rilpivirine.

Author

Bailón, L, Sábato, S, Coll, J, Santos, J R, Miranda, C, Puig, T, D´Avolio, A, Paredes, R, Moltó, J, and Negredo, E

Subjects
HIV infections
Abstract

This article discusses a case of virological failure in a person with HIV who was switched to long-acting therapy with cabotegravir and rilpivirine. The patient experienced an increase in viral load after starting the new treatment, despite having no prior exposure to certain medications or previous treatment interruptions. The article suggests that factors such as HIV subtype, preexisting resistance mutations, and low drug concentrations may contribute to virological failure with this therapy. The case highlights the importance of close monitoring and further research in this area. [Extracted from the article]

Published
2024
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49. Intraductal papillary mucinous neoplasm of the pancreas. Personal series and synthetic review

Author

F. Gallucci, D. Avolio, R. de Ritis, L. Ferrara, U. Valentino, and G. Uomo

Subjects
Pancreatic neoplasm, Mucinous pancreatic tumor, Pancreatic cyst, Diagnosis, Treatment, Medicine
Abstract

Intraductal papillary mucinous neoplasms (IPMNs) are rare pancreatic tumors, accounting for less than 1-2% of all neoplasms of the pancreas. The main characteristic of IPMNs is their favorable prognosis, as these pre-malignant or malignant lesions are usually slow-growing tumors and radical surgery is frequently possible. According to the localization of the lesions, three different tumor types have been identified: the main-duct IPMN, the branch-duct IPMN and the mixed-type IPMN (involving both the main pancreatic duct and the side branches). IMPNs do not present pathognomonic signs or symptoms. The obstruction of the main pancreatic duct system may cause abdominal pain and acute pancreatitis (single or recurrent episodes). The tumor may be incidentally discovered in asymptomatic patients, particularly in those with branch-duct IPMNs. In clinical practice, any non-inflammatory cystic lesion of the pancreas should be considered as possible IPMN. Computed tomography, magnetic resonance imaging with cholangiopancreatography and endoscopic ultrasonography can localize an IPMN and assess its morphology and size. The choice between non-operative and surgical management depends on the risk of malignancy and on the definitive distinction between benign and malignant IPMNs. Main-duct IPMNs have a high risk of malignant degeneration, especially in older patients. The clinical and radiological features, as well as treatment and outcome, of eight patients with IPMN (five with main-duct, two with branch-duct and one with mixed-type) observed by the authors over the last ten years are presented.

Published
2012
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