1,038 results on '"Dötsch, Volker"'
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2. Efficient determination of the accessible conformation space of multi-domain complexes based on EPR PELDOR data
3. E. coli “Stablelabel” S30 lysate for optimized cell-free NMR sample preparation
4. The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways
5. Fuzzy interactions between the auto-phosphorylated C-terminus and the kinase domain of CK1δ inhibits activation of TAp63α
6. DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma
7. An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant
8. Designed Ankyrin Repeat Proteins as a tool box for analyzing p63
9. Disease-related p63 DBD mutations impair DNA binding by distinct mechanisms and varying degree
10. eLife assessment: PAbFold: Linear Antibody Epitope Prediction using AlphaFold2
11. eLife assessment: Targeted protein degradation systems to enhance Wnt signaling
12. K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors
13. Dichotomous transactivation domains contribute to growth inhibitory and promotion functions of TAp73
14. eLife assessment: The RNA-binding activity of the TRIM-NHL protein NHL-2 is essential for miRNA-mediated gene regulation
15. eLife assessment: Molecular dissection of PI3Kβ synergistic activation by receptor tyrosine kinases, GβGγ, and Rho-family GTPases
16. eLife assessment: Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling
17. eLife assessment: Deciphering the actin structure-dependent preferential cooperative binding of cofilin
18. eLife assessment: Endogenous oligomer formation underlies DVL2 condensates and promotes Wnt/β-catenin signaling
19. eLife assessment: Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase dependent mechanism
20. eLife assessment: Ligand bias underlies differential signaling of multiple FGFs via FGFR1
21. Structural diversity of p63 and p73 isoforms
22. Cotranslational assembly of membrane protein/nanoparticles in cell-free systems
23. Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes
24. A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1
25. Applications of Cell-Free Synthesized Membrane Protein Precipitates
26. Cell-Free Expression of GPCRs into Nanomembranes for Functional and Structural Studies
27. eLife assessment: Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin
28. eLife assessment: Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation
29. eLife assessment: Dynamic 1D search and processive nucleosome translocations by RSC and ISW2 chromatin remodelers
30. eLife assessment: X-Ray Structure and enzymatic study of a Bacterial NADPH oxidase highlight the activation mechanism of eukaryotic NOX
31. A ribosome-associating chaperone mediates GTP-driven vectorial folding of nascent eEF1A
32. eLife assessment: Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens
33. eLife assessment: Kinases in motion: impact of protein and small molecule interactions on kinase conformations
34. eLife assessment: Rapid, DNA-induced interface swapping by DNA gyrase
35. eLife assessment: The molecular basis of Abelson kinase regulation by its αI-helix
36. eLife assessment: A kinase to cytokine explorer to identify molecular regulators and potential therapeutic opportunities
37. eLife assessment: Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock
38. eLife assessment: Reassessing the substrate specificities of the major Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM
39. eLife assessment: H3-OPT: Accurate prediction of CDR-H3 loop structures of antibodies with deep learning
40. K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific interactors.
41. eLife assessment: Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery
42. Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy
43. Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms
44. Enhanced pro-apoptosis gene signature following the activation of TAp63α in oocytes upon γ irradiation
45. Mechanisms of quality control differ in male and female germ cells
46. eLife assessment: Unveiling the domain-specific and RAS isoform-specific details of BRAF kinase regulation
47. eLife assessment: Structural and mechanistic insight into ribosomal ITS2 RNA processing by nuclease-kinase machinery
48. eLife assessment: Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin
49. eLife assessment: Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase dependent mechanism
50. eLife assessment: Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock
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