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4. Multicenter comparison of transcatheter aortic valve implantation with the self-expanding ACURATE neo2 versus Evolut PRO transcatheter heart valves

Author

Rheude, Tobias, Pellegrini, Costanza, Landt, Martin, Bleiziffer, Sabine, Wolf, Alexander, Renker, Matthias, Neuser, Jonas, Dörr, Oliver, Allali, Abdelhakim, Rudolph, Tanja K., Wambach, Jan Martin, Widder, Julian D., Singh, Parminder, Berliner, Dominik, Alvarez-Covarrubias, Hector A., Richardt, Gert, Xhepa, Erion, Kim, Won-Keun, and Joner, Michael

Published
2024
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8. Kommentar zum Konsensuspapier zur renalen Denervation der Arbeitsgruppe Hypertonie der European Society of Cardiology (ESC) und der European Association of Percutaneous Cardiovascular Interventions (EAPCI)

Author

Halbach, Marcel, Boer, Jana, Böhm, Michael, Busch, Sonia, Dörr, Oliver, Elsässer, Albrecht, Erbel, Christian, Galle, Jan-Christoph, Kintscher, Ulrich, Limbourg, Florian P., Reuter, Hannes, Rump, Lars C., Schmieder, Roland, Schunkert, Heribert, van der Giet, Markus, Weil, Joachim, and Mahfoud, Felix

Published
2023
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15. Manual der Arbeitsgruppe Interventionelle Kardiologie (AGIK) der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e.V. (DGK): Teil 2: „Durchführung der perkutanen Koronarintervention“

Author

Nef, Holger M., Achenbach, Stephan, Birkemeyer, Ralf, Bufe, Alexander, Dörr, Oliver, Elsässer, Albrecht, Gaede, Luise, Gori, Tommaso, Hoffmeister, Hans M., Hofmann, Felix J., Katus, Hugo A., Liebetrau, Christoph, Massberg, Steffen, Pauschinger, Matthias, Schmitz, Thomas, Süselbeck, Tim, Voelker, Wolfram, Wiebe, Jens, Zahn, Ralf, Hamm, Christian, Zeiher, Andreas M., and Möllmann, Helge

Published
2021
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18. Feasibility of Coronary Access in Patients With Acute Coronary Syndrome and Previous TAVR

Author

Kim, Won-Keun, Pellegrini, Costanza, Ludwig, Sebastian, Möllmann, Helge, Leuschner, Florian, Makkar, Raj, Leick, Jürgen, Amat-Santos, Ignacio J., Dörr, Oliver, Breitbart, Philipp, Jimenez Diaz, Victor A., Dabrowski, Maciej, Rudolph, Tanja, Avanzas, Pablo, Kaur, Jatinderjit, Toggweiler, Stefan, Kerber, Sebastian, Ranosch, Patrick, Regazzoli, Damiano, Frank, Derk, Landes, Uri, Webb, John, Barbanti, Marco, Purita, Paola, Pilgrim, Thomas, Liska, Branislav, Tabata, Noriaki, Rheude, Tobias, Seiffert, Moritz, Eckel, Clemens, Allali, Abdelhakim, Valvo, Roberto, Yoon, Sung-Han, Werner, Nikos, Nef, Holger, Choi, Yeong-Hoon, Hamm, Christian W., and Sinning, Jan-Malte

Published
2021
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20. Manual der Arbeitsgruppe Interventionelle Kardiologie (AGIK) der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e. V. (DGK): Teil 1: „Durchführung der diagnostischen Herzkatheteruntersuchung“

Author

Nef, Holger M., Achenbach, Stephan, Birkemeyer, Ralf, Bufe, Alexander, Dörr, Oliver, Elsässer, Albrecht, Gaede, Luise, Gori, Tommaso, Hoffmeister, Hans M., Hofmann, Felix J., Katus, Hugo A., Liebetrau, Christoph, Massberg, Steffen, Pauschinger, Matthias, Schmitz, Thomas, Süselbeck, Tim, Voelker, Wolfram, Wiebe, Jens, Zahn, Ralf, Hamm, Christian, Zeiher, Andreas M., and Möllmann, Helge

Published
2021
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22. Impact of Anesthesia Strategy and Valve Type on Clinical Outcomes After Transcatheter Aortic Valve Replacement

Author

Feistritzer, Hans-Josef, Kurz, Thomas, Stachel, Georg, Hartung, Philipp, Lurz, Philipp, Eitel, Ingo, Marquetand, Christoph, Nef, Holger, Doerr, Oliver, Vigelius-Rauch, Ursula, Lauten, Alexander, Landmesser, Ulf, Treskatsch, Sascha, Abdel-Wahab, Mohamed, Sandri, Marcus, Holzhey, David, Borger, Michael, Ender, Jörg, Ince, Hüseyin, Öner, Alper, Meyer-Saraei, Roza, Hambrecht, Rainer, Wienbergen, Harm, Fach, Andreas, Augenstein, Thomas, Frey, Norbert, König, Inke R., Vonthein, Reinhard, Funkat, Anne-Kathrin, Berggreen, Astrid E., Heringlake, Matthias, Desch, Steffen, de Waha-Thiele, Suzanne, and Thiele, Holger

Published
2021
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28. Impact of Vascular Function on Maximum Power Output in Elite Handball Athletes

Author

Bauer, Pascal, Kraushaar, Lutz, Most, Astrid, Hölscher, Sophie, Tajmiri- Gondai, Shahin, Dörr, Oliver, Troidl, Christian, Bauer, Timm, Nef, Holger, Hamm, Christian W., and Keller, Till

Abstract

Purpose: To evaluate vascular function and its relationship to cardiorespiratory fitness in professional handball athletes. Method: We examined 30 male professional handball athletes (age 27 [plus or minus] 4 y) and 10 male sedentary controls (age 26[plus or minus] 5 y) at rest. The workup included exercise testing via ergometry. To assess vascular function, a validated electronic model of the arterial tree (vasc assist 2 [Registered Trade Mark]) was used. It replicates noninvasively acquired pulse pressure waves by modulating the relevant functional parameters of compliance, resistance, inertia, pressure, and flow. The maximum oxygen uptake (VO2max) was estimated using the validated heart rate ratio method. Results: Athletes had a significantly lower systolic and diastolic central blood pressure ([mini c]BP) compared to controls (102[plus or minus]9/60[plus or minus] 9 vs. 110[plus or minus]8/74[plus or minus]9 mmHg, p[less than] 0.01), whereas aortic pulse wave velocity (PWV) (6.2[plus or minus]0.8 vs. 6.3[plus or minus] 0.5 m/s, p = 0.45) and augmentation index at a heart rate of 75 (Aix[at]75) (-4[plus or minus]12 vs. -13[plus or minus]16%, p = 0.06) were not different. Resistance index (R) (15.9[plus or minus]4.4 vs. 10.6[plus or minus]0.6, p = 0.001) and maximum power output (MPO) (3.55 [plus or minus]0.54 vs. 2.46[plus or minus]0.55 Watt/kg, p[less than] 0.001) were significantly higher in athletes compared to controls. We found no relevant correlation between MPO, resting heart rate, PWV, Aix[at]75, and cBP. A higher VO2max (p = 0.02) and a lower R (p[less than]0.01) were significant predictors of a higher MPO in athletes. Conclusion: R had an independent and strong correlation to MPO in athletes, which might help to disentangle the contribution of aerobic capacity and arterial function to physical power.

Published
2019
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29. Aortic valve replacement in Germany in 2019

Author

Gaede, Luise, Blumenstein, Johannes, Husser, Oliver, Liebetrau, Christoph, Dörr, Oliver, Grothusen, Christina, Eckel, Clemens, Al-Terki, Hani, Kim, Won-Keun, Nef, Holger, Tesche, Christian, Hamm, Christian W., Elsässer, Albrecht, Achenbach, Stephan, and Möllmann, Helge

Published
2021
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31. The role of Matrix Metalloproteinase-2 and Galectin-3 as predictive biomarkers for all-cause mortality in patients undergoing transfemoral transcatheter aortic valve implantation.

Author

Piayda, Kerstin, Heilemann, Julian Tim, Keranov, Stanislav, Schulz, Luisa, Arsalan, Mani, Liebetrau, Christoph, Kim, Won-Keun, Hofmann, Felix J., Bauer, Pascal, Voss, Sandra, Troidl, Christian, Sossalla, Samuel T., Hamm, Christian W., Nef, Holger M., and Dörr, Oliver

Subjects
HEART valve prosthesis implantation, GALECTINS, MORTALITY, DISEASE risk factors, AORTIC stenosis, ARTIFICIAL knees
Abstract

Currently available risk scores fail to accurately predict morbidity and mortality in patients with severe symptomatic aortic stenosis who undergo transcatheter aortic valve implantation (TAVI). In this context, biomarkers like matrix metalloproteinase-2 (MMP-2) and Galectin-3 (Gal-3) may provide additional prognostic information. Patients with severe aortic stenosis undergoing consecutive, elective, transfemoral TAVI were included. Baseline demographic data, functional status, echocardiographic findings, clinical outcomes and biomarker levels were collected and analysed. The study cohort consisted of 89 patients (age 80.4 ± 5.1 years, EuroScore II 7.1 ± 5.8%). During a median follow-up period of 526 d, 28 patients (31.4%) died. Among those who died, median baseline MMP-2 (alive: 221.6 [170.4; 263] pg/mL vs. deceased: 272.1 [225; 308.8] pg/mL, p < 0.001) and Gal-3 levels (alive: 19.1 [13.5; 24.6] pg/mL vs. deceased: 25 [17.6; 29.5] pg/mL, p = 0.006) were higher than in survivors. In ROC analysis, MMP-2 reached an acceptable level of discrimination to predict mortality (AUC 0.733, 95% CI [0.62; 0.83], p < 0.001), but the predictive value of Gal-3 was poor (AUC 0.677, 95% CI [0.56; 0.79], p = 0.002). Kaplan–Meier and Cox regression analyses showed that patients with MMP-2 and Gal-3 concentrations above the median at baseline had significantly impaired long-term survival (p = 0.004 and p = 0.02, respectively). In patients with severe aortic stenosis undergoing transfemoral TAVI, MMP-2 and to a lesser extent Gal-3, seem to have additive value in optimizing risk prediction and streamlining decision-making. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Association of cardiorespiratory fitness level with vascular function and subclinical atherosclerosis in the elderly

Author

Größer, Vincent, primary, Weyh, Christopher, additional, Böttrich, Tim, additional, Frech, Torsten, additional, Nolte, Svenja, additional, Sommer, Natascha, additional, Huber, Magdalena, additional, Eder, Klaus, additional, Dörr, Oliver, additional, Hoelscher, Sophie, additional, Weber, Rebecca, additional, Akdogan, Ebru, additional, Nef, Holger, additional, Most, Astrid, additional, Hamm, Christian W., additional, Krüger, Karsten, additional, and Bauer, Pascal, additional

Published
2023
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34. Association of central blood pressure with an exaggerated blood pressure response to exercise among elite athletes

Author

Most, Astrid, primary, Kraushaar, Lutz, additional, Dörr, Oliver, additional, Keranov, Stanislav, additional, Hoelscher, Sophie, additional, Weber, Rebecca, additional, Akdogan, Ebru, additional, Groesser, Vincent, additional, Husain-Syed, Faeq, additional, Nef, Holger, additional, Hamm, Christian W., additional, and Bauer, Pascal, additional

Published
2023
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50. Cardiovascular Emergency Surgery After Acute Renal Failure: A Case Report

Author

Boeder Niklas F., Dörr Oliver, Rutsatz Wiebke, Bauer Timm, and Nef Holger M.

Subjects
aortic dissection, emergency room, trauma room, communication, syncope, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

We describe the case of a 68-year-old patient who was admitted to the trauma unit with anisocoria after pre-hospital resuscitation upon loss of consciousness. An intracranial bleeding was ruled out. The patient was admitted to the cardiology ward with the initial diagnosis of a syncope due to myocarditis, as myocardial necrosis markers were slightly elevated. The suspicion of an acute aortic dissection (AAD) was raised when the patient developed kidney failure and a progressive aortic regurgitation. He underwent emergency surgery for an acute type A AAD. Renal function recovered completely and, fortunately, the patient was discharged 10 days later.

Published
2018
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