327 results on '"Díaz, J. Fernando"'
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2. Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes
3. Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy
4. Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site
5. Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures
6. Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide.
7. PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin
8. Synthesis and Structure-Activity Relationship Studies of Dioxane- and Oxathiane-Based Analogs of (–)-Zampanolide
9. Taxanes convert regions of perturbed microtubule growth into rescue sites
10. Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the αT5 loop
11. Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents
12. Lateral wedge insoles and their use in ankle instability
13. Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions
14. Abstract 6243: The novel antitubulin agent PM534 exhibits potent antitumoral and antiangiogenic properties in vitro and in vivo
15. Abstract 6239: PM534 is a novel microtubule-destabilizing agent with high affinity and potent antineoplastic properties
16. Structural insight into the stabilization of microtubules by taxanes
17. High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells
18. Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics
19. Synthesis and Structure-Activity Relationship Studies of C(13)-Desmethylene-(−)-Zampanolide Analogs
20. Front Cover: Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics (Chem. Eur. J. 5/2023)
21. Alternative Approaches to Understand Microtubule Cap Morphology and Function
22. Chemical modulation of microtubule structure through the laulimalide/peloruside site
23. Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics
24. TRAPPII regulates exocytic Golgi exit by mediating nucleotide exchange on the Ypt31 ortholog RabE RAB11
25. Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances
26. Protein Shape and Assembly Studied with X-Ray Solution Scattering: Fundaments and Practice
27. A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
28. Taxanes convert regions of perturbed microtubule growth into rescue sites
29. Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules
30. Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders
31. Synthesis of N-acyl Derivatives of Aminocombretastatin A-4 and Study of their Interaction with Tubulin and Downregulation of c-Myc
32. The Use of Ion-Selective Microelectrodes to Study Cellular Transport Processes
33. Structural and Functional Insights Into Skl and Pal Endolysins, Two Cysteine-Amidases With Anti-pneumococcal Activity. Dithiothreitol (DTT) Effect on Lytic Activity
34. Structural insight into the stabilization of microtubules by taxanes
35. Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes
36. Studies toward the Synthesis of an Oxazole-Based Analog of (−)-Zampanolide
37. Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes
38. Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells
39. Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells
40. El recuerdo de la Guerra de Granada (1482-1492) en la cronística peninsular del siglo XVI
41. Taxanes convert regions of perturbed microtubule growth into rescue sites
42. El recuerdo de la Guerra de Granada (1482-1492) en la cronística peninsular del siglo XVI
43. Fluorescent Taxoid Probes for Microtubule Research
44. Protein Shape and Assembly Studied with X-Ray Solution Scattering: Fundaments and Practice
45. Structural Basis of Noscapine Activation for Tubulin Binding
46. Structural model for differential cap maturation at growing microtubule ends
47. Two antagonistic microtubule targeting drugs act synergistically to kill cancer cells
48. Identification of the guanine nucleotide exchange factor for SAR1 in the filamentous fungal model Aspergillus nidulans
49. Author response: Structural model for differential cap maturation at growing microtubule ends
50. Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
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