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O estudo testou, por meio de modelagem econométrica, se empresas do mercado de capitais do Brasil que contêm mais empregados desmotivados são as que obtêm um menor desempenho de mercado. O presente trabalho avança ao adotar a rotatividade de pessoas nas empresas (turnover) como proxy para a mensuração da (des)motivação dos funcionários. Em um contexto organizacional, há uma premissa geral de que funcionários mais motivados exercerão melhor desempenho e, pela lógica do contraditório, é possível assumir, também, que, quanto mais pessoas saem intencionalmente da empresa, mais desmotivadas estão. Para mensurar o desempenho da empresa, foi utilizado o retorno de mercado. Apesar de sofrer influências externas, percebe-se que a média da cotação das ações das empresas no mercado pode refletir e representar o desempenho de uma organização. Nesse sentido, os resultados empíricos esperados buscaram corroborar a hipótese de que a motivação dos funcionários tem um impacto positivo no desempenho corporativo e tem valor relevante refletido nos preços das ações, isto é, o mercado valoriza tal intangível. Uma vez que o coeficiente da variável “desmotivação” foi negativo e estatisticamente significativo, confirmou-se a hipótese central e, portanto, é possível afirmar que existe relação inversa entre o desempenho de mercado da empresa, medido pelo retorno das ações, e a desmotivação dos empregados.

Background Nut consumption has been related to improvements on cardiometabolic parameters and reduction in the severity of atherosclerosis mainly in primary cardiovascular prevention. The objective of this trial is to evaluate the effects of the Brazilian Cardioprotective Diet (DIetaCArdioprotetoraBrasileira, DICA Br) based on consumption of inexpensive locally accessible foods supplemented or not with mixed nuts on cardiometabolic features in patients with previous myocardial infarction (MI). Methods DICA-NUTS study is a national, multicenter, randomized 16-week follow-up clinical trial. Patients over 40 years old with diagnosis of previous MI in the last 2 to 6 months will be recruited (n = 388). A standardized questionnaire will be applied to data collection and blood samples will be obtained. Patients will be allocated in two groups: Group 1: DICA Br supplemented with 30 g/day of mixed nuts (10 g of peanuts, 10 g of cashew, 10 g of Brazil nuts); and Group 2: only DICA Br. The primary outcome will consist of LDL cholesterol means (in mg/dL) after 16 weeks of intervention. Secondary outcomes will consist of other markers of lipid profile, glycemic profile, and anthropometric data. Discussion It is expected that DICA Br supplemented with mixed nuts have superior beneficial effects on cardiometabolic parameters in patients after a MI, when compared to DICA Br. Trial registration ClinicalTrials.gov Identifier NCT03728127. First register: November 1, 2018; Last update: June 16, 2021. World Health Organization Universal Trial Number (WHO-UTN): U1111-1259-8105.

The management of patients with dyslipidemia (DLP) requires intensive medical follow-up as an essential part of treatment and to reduce the risk of cardiovascular (CV) outcomes. The aim of this study was to evaluate whether adherence to medical treatment changed the prevalence of CV disease events in a retrospective 7-year follow-up analysis.This retrospective study involved 92 patients divided into two groups according to their adherence: the REG group with 64 patients who had medical appointments from 2012 to 2018, and the DROP group, with 28 patients who had medical appointments in 2012 but did not complete regular appointments until 2018. Cox proportional hazard models were fitted to estimate hazard ratios associated with CV outcomes as primary endpoints.We observed a total of 32 cases of acute myocardial infarction (AMI) in the study population, 17 (338.41 pY) in the REG group and 15 (62.97 pY) in the DROP group. An increased hazard of AMIs was observed in the DROP group compared with the REG group by follow-up time (p 0.001). We found that previous events of AMI and congestive heart failure (CHF) were associated with progression to treatment dropout (p 0.05) and that two drugs were considered a risk factor for treatment dropout, diuretics and fibrates (p 0.05).A reduced hazard of AMI was observed in patients who complete a greater number of medical appointments and receive multidisciplinary treatment on a regular basis.

PurposeThis paper aims to further the discussion on Building Information Modelling (BIM) legal requirements, providing a framework with key energy parameters capable of supporting the Appointing Party in the definition of the Exchange Information Requirements (EIR) for a BIM project appointment. The EIR is described in ISO-19650–1:2018 as a fundamental step in the information delivery cycle.Design/methodology/approachA literature review on the topic of BIM energy analysis was completed to identify current knowledge gaps and support the need for the proposed framework. Afterwards, the framework was established based on the review findings and the authors’ domain knowledge. The applicability of the proposed framework was assessed through a case study, where several energy simulations were performed in three different design stages of the same BIM model.FindingsThis study identified a lack of standards and legislation capable of supporting the Appointing Party in the definition of energy-related BIM requirements. To this end, a new framework is proposed to mediate existing practices, linking prior knowledge with BIM’s new reality. The study showcases the applicability of the framework, identifying that the performance of different energy studies involves distinct Level of Development (LOD) requirements, which in turn have an impact on the modelling time and cost.Originality/valueA BIM framework for the specification of information requirements in energy-related projects was developed to support the Appointing Party. The framework presents appropriate parameters for energy analysis in each design stage, as well as the suitable LOD for the BIM model.

The construction industry has one of the highest occupational accident incidence rates among all economic sectors. Currently, building information modelling (BIM) appears to be a valuable tool for analysing occupational safety issues throughout the construction life cycle of projects, helping to avoid hazards and risks and, consequently, increasing safety. This work investigates BIM methodology and the application of related technologies for building safety planning and demonstrates the potential of this technology for the integrated implementation of safety measures during the design phase and construction site management. The first step consisted of a literature review on applying BIM-related technologies for safety in the design and planning phases. Following this, to show the potentialities of construction simulation, a case study based on BIM 4D to prevent falls from height was developed. With BIM 4D, it is possible to follow the construction process over time, giving the construction safety technicians, designers, supervisors and managers the capability to analyse, in each phase, the potential risks and identify which safety measures should be implemented. BIM can effectively integrate safety measures from the design phase to the construction and use phase and enable integrated safety planning within construction planning, leading to reliable safety management throughout the construction process.

As is known, the construction industry has one of the highest occupational accidents incidence rates among all economic sectors. Currently, Building Information Modeling (BIM) appears as a tool that addresses occupational safety issues throughout the construction life cycle projects, avoiding hazards and risks and, consequently, increasing safety. This work investigates BIM methodology and related technologies application for building safety planning in construction and demonstrates the potential of this technology for the integrated implementation of safety measures during the design phase and the construction site management. The first step consisted of a literature review on the application of BIM in safety in the design and planning phases. Following, to show the potentialities of construction simulation, a case study based on BIM 4D to prevent falls from height was developed. With BIM 4D, it is possible to follow the construction process over time, giving the construction safety technicians’, designers, supervisors and managers the capability to analyse, in each phase, the potential risks and which safety measures should be implemented. BIM can effectively integrate safety measures from the design phase to the construction and use phase and do integrated safety planning within construction planning, leading to reliable safety management throughout the construction process.

O presente trabalho investigativo tem como foco debater aspectos que serelacionam com a discussão sobre o direito à cidade, a partir da realidade do distrito daMatinha dos Pretos, situado no município de Feira de Santana. A proposta é apontarelementos sobre a formação do espaço, do território, da relação campo-cidade e daindustrialização-urbanização, entre outros, tomando como base de análise,evidentemente, a realidade brasileira como um todo.

Background: Cardiovascular diseases (CVDs) are a global public health problem. Dietary patterns can modulate different aspects of the atherosclerotic process and cardiovascular risk factors. The analysis of ultra-processed foods (UPF) consumption has been an important indicator of diet quality.Objective: The aim of this study was to evaluate food intake according to levels of processing and investigate the association between UPF consumption and dietary inadequacy in patients with coronary artery disease.Methods: Cross-sectional study with 276 patients in tertiary prevention of CVDs. Clinical, anthropometric and laboratory evaluations were performed. Food intake was evaluated in relation to macronutrients and micronutrients, and the consumed food items classified according to NOVA. The Kruskal-Wallis tests were used and p

A presente pesquisa se insere nas discussões acerca da relação entre a sociedade e a forma de ocupação dos espaços, na qual situa, mais especificamente, como essa relação ocorre e se desenvolve na sociedade atual. Espaço, de acordo com SANTOS (2008), apresenta duas dimensões; sua dimensão natural – objetos geográficos naturais e artificiais, presentes no território -, mas se estende à dimensão social, na medida em que as reflexões sobre os aspectos naturais no território/espaço são realizadas de maneira articulada às análises sobre a interferência dos seres humanos no meio.

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A new method that combines ultrasonic assisted extraction (UAE) with ionic liquids (ILs) was proposed to extract phycobiliproteins from the microalgae Spirulina (Arthrospira) platensis. Extraction of the pigments was carried out in an ultrasonic bath at 25 °C and at a frequency of 25 kHz. The effects of pH and solvent:biomass ratio were evaluated through a central rotational composite design and response surface methodology were used to determine the best extraction conditions. Solvents used were protic ionic liquids (PILs) 2-hydroxy ethylammonium acetate (2-HEAA), 2-hydroxy ethylammonium formate (2-HEAF), their equimolar mixture (2-HEAA+2-HEAF) (1:1 v/v) and the commercial ionic liquid, 1-butyl-3-methylimidazolium chloride [Bmim][Cl] and sodium phosphate buffer (0.1 M) as a control. Results showed that the PILs were able to extract the phycobiliproteins from microalgae. The pH was the most significant variable. Solvent:biomass ratio was also significant in the extraction process. The highest concentrations of phycobiliproteins were observed using 2-HEAA +2-HEAF as solvent at pH 6.50 and solvent:biomass ratio 7.93 mL·g−1 within 30 min of extraction. Allophycocyanin was the pigment extracted in greater quantity (6.34 mg·g−1), followed by phycocyanin (5.95 mg·g−1) and phycoerythrin (2.62 mg·g−1). Scanning electron microscopy (SEM) revealed that the ultrasound affect the cellular structure of the microalgae.

A análise do meio físico (relevo, geologia, água e clima) representa uma das principais bases para o estudo do processo de urbanização. Como se configura esse meio físico, se há planejamento de determinadas áreas urbanas, quais são os limites e as potencialidades relacionadas ao seu uso, são algumas questões que se pode explorar a partir da análise do meio físico.As análises, sobre o meio físico e os processos de urbanização, existentes, dialogam diretamente com o estudo sobre o direito à cidade. Há limites em discorrermos sobre como os seres humanos organizam a vida nas cidades e as problemáticas envolvidas, sem a devida compreensão dos aspectos de urbanização de cada região.Harvey (2014), um grande estudioso na área, inicia as discussões sobre o direito à cidade, demarcando duas grandes posições; uma refere-se à defesa que o direito a cidade é mais do que um direito/acesso individual, sendo assim, um direito coletivo, visto que, através do exercício do poder coletivo sobre os processos de urbanização, se faz possível reinventar e recriar o meio em que se vive; outra situa o estudo (direito à cidade) no atual modelo de sociedade, o capitalismo. Sendo esse último a base necessária para as análises contemporâneas.Destarte, diante desses elementos gerais, o atual plano de trabalho “O Meio físico de Feira de Santana e o Direito à cidade” reafirma sua importância, visto que se objetiva relacionar esses aspectos (meio físico e direito à cidade) através dos estudos previamente realizados. Esses estudos tratam da realidade do meio físico do município de Feira de Santana, mais especificamente, seus 8 distritos (Bonfim de Feira, Ipuaçu, Jaguara, Maria Quitéria, Tiquaruçu, Humildes, Matinha e Jaiba), e foram realizados através dos antigos planos de trabalho de iniciação científica, vinculados ao projeto “Integração de Dados sobre os Aspectos do Meio Físico do Município de Feira de Santana, Ba”. Esses materiais possibilitam realizar um diagnóstico dessa relação com base no município de Feira de Santana, apontando seus limites e suas potencialidades.

O presente artigo tem por objetivo enfatizar a importância do reconhecimento do nome social dos transexuais, já que são pessoas cuja identidade de gênero não corresponde à sua condição biológica. Pretende-se analisar com base na doutrina específica as mudanças sociais que elas atravessam, bem como o direito de poderem, com a autodeclaração, ver seu nome social reconhecido em cartório. Este artigo apresenta a seguinte questão-problema: De que forma o nome civil do transexual contribui para afirmação de seus direitos de personalidade? Pretende-se avaliar a função do nome perante a sociedade, como representação escrita e identificadora de alguém, examinando-se a referida votação, doutrinas, artigos científicos, posicionamento dos tribunais e a literatura científica a respeito do assunto. Traça-se uma análise a respeito desse direito que as pessoas transexuais conquistaram. Justifica-se a abordagem desse tema pela relevância social que perpassa o direito ao nome, como elemento identificador, que se transforma no reconhecimento jurídico, a partir de um recorte atual. Demonstra-se a necessidade de se identificar o gênero transexual como sujeito de direito, reconhecendo-lhes o direito de personalidade, quanto à identidade social e apresentar a alteração introduzida por decisão do STF: possibilidade de transexuais alterarem o nome no registro civil sem a realização de cirurgia de redesignação sexual. Emprega-se metodologia qualitativa, por meio de revisão jurisprudencial e bibliográfica baseada em autores estudiosos do tema tais como Cristiano Chaves de Farias, Nelson Rosenvald, Maria Berenice Dias, Adriano Cupis e Tereza Rodrigues Vieira.

Objectives Complete and accurate human skeletal inventory is seldom possible in archaeological and forensic cases involving severe fragmentation. In such cases, skeletal mass comparisons with published references may be used as an alternative to assess skeletal completeness but they are too general for a case-by-case routine analysis. The objective is to solve this issue by creating linear regression equations to estimate the total mass of a skeleton based on the mass of individual bones. Materials and Methods Total adult skeletal mass and individual mass of the clavicle, humerus, femur, patella, carpal, metacarpal, tarsal, and metatarsal bones were recorded in a sample of 60 skeletons from the 21st century identified skeletal collection (University of Coimbra). The sample included 32 females and 28 males with ages ranging from 31 to 96 years (mean = 76.4; sd = 14.8). Skeletal mass linear regression equations were calculated based on this sample. Results The mass of individual bones was successfully used to predict the approximate total mass of the adult skeleton. The femur, humerus, and second metacarpal were the best predictors of total skeletal mass with root mean squared errors ranging from 292.9 to 346.1 g. Discussion Linear regression was relatively successful at estimating adult skeletal mass. The non-normal distribution of the sample in terms of mass may have reduced the predictive power of the equations. These results have clear impact for bioanthropology, especially forensic anthropology, since this method may provide better estimates of the completeness of the skeleton or the minimum number of individuals. Am J Phys Anthropol, 2016. © 2016 Wiley Periodicals, Inc.

Phycobiliproteins are potential molecules for use in various applications. Although phycobiliproteins extraction classical methods are reproducible and show good yields, they are generally time-consuming and require the use of high energy consumption and/or large volumes of solvent. Therefore, it is necessary the development of new eco-friendlier process by extraction techniques, permitting the transfer of the results obtained in laboratory scale for industrial. Then, microwave-assisted extraction using protic ionic liquid as solvent was proposed and optimized to extract phycobiliproteins from Arthrospira platensis in an efficient manner. The protic ionic liquids (PILs): 2-hydroxyethylammonium acetate (2-HEAA), 2-hydroxyethylammonium formate (2-HEAF), their equimolar mixture (2-HEAA + 2-HEAF), and the commercial ionic liquid 1-butyl-3-methylimidazolium chloride [Bmim]Cl were used as solvents, and sodium phosphate buffer as a control and the conditions of extraction were evaluated. The irradiation power was the most significant variable for the extraction process, and it showed a negative effect. The process conducted at 62 W and pH 7.0, using 2-HEAA + 2-HEAF and a solvent: biomass ratio of 10 mL∙g−1, showed the highest phycobiliproteins concentrations. The purity obtained for phycocyanin, allophycocyanin and phycoerythrin were 1.22, 1.03, and 0.71, respectively. The mixture of the PILs (2-HEAA + 2-HEAF) can be reused for three cycles for extraction of allophycocyanin. The extraction of phycobiliproteins using microwave and ionic liquids was efficient and the degree of purity and antioxidant activity achieved allows the application of these pigments in food and cosmetics.

The thermal comfort retrofitting of existing transport stations is an opportunity to increase the interest in the use of public transportation while improving the performance of the building, and consequently reduce the energy consumption and greenhouse gas emissions. The aim of this study is to implement an innovative methodology to evaluate and improve the thermal comfort of an existing semi-outdoor bus station in the winter season through the application of retrofit solutions. Some research was recently published concerning the evaluation of the thermal environment in semi-outdoor spaces showing that thermal comfort is achievable. The thermal environment of the station was evaluated through an experimental campaign involving the measurement of physical parameters and the application of questionnaires to the passengers. The results of the questionnaires indicate a colder sensation in the morning period and a lower percentage of dissatisfied people when compared to the application of the thermal comfort models. However, the preference of the passengers for a warmer environment was also identified. A realistic thermal comfort target, adapted to this semi-outdoor space, could, therefore, be defined. An innovative integrated methodology articulated in a BIM2BEM approach was applied in this work. The methodology included the joint application of Building Information Modeling and Building Energy Modeling, allowing the simulation of different retrofitting alternatives. The decision-making process was completed with an economic analysis of the alternatives, using the Savings-to-Investment Ratio (SIR) as an indicator. In order to improve the passengers’ thermal comfort, the option to create an enclosed heated waiting area was technically supported by the results of the study.

Construction is still a sector with high incidence of accidents. Therefore, it’s imperative to implement methodologies to improve safety in this sector. Building Information Modeling (BIM) emerges as a tool that allows the implementation of safety throughout the life cycle of a construction project, minimizing hazards and risks, consequently increasing safety. This paper aims to demonstrate BIM’s methodology potential for the implementation of safety measures throughout planning and the application of this information on the worksite management. A case study based on BIM 4D was developed in which safety measures to prevent falls from height were applied. With 4D simulation, it is possible to follow the execution of work giving Safety Technicians the capability to visualize in each phase which measures should be implemented. In conclusion, BIM contributes to safety measures integration from the design phase to the construction phase, making safety management easier throughout all construction project phases.

Construction is still a sector with high incidence of accidents. Therefore, it's imperative to implement methodologies to improve safety in this sector. Building Information Modeling (BIM) emerges as a tool that allows the implementation of safety throughout the life cycle of a construction project, minimizing hazards and risks, consequently increasing safety. This paper aims to demonstrate BIM's methodology potential for the implementation of safety measures throughout planning and the application of this information on the worksite management. A case study based on BIM 4D was developed in which safety measures to prevent falls from height were applied. With 4D simulation, it is possible to follow the execution of work giving Safety Technicians the capability to visualize in each phase which measures should be implemented. In conclusion, BIM contributes to safety measures integration from the design phase to the construction phase, making safety management easier throughout all construction project phases.

Objective: To determine the time required for pH buffering by saliva after use sugary(S), sugar-free (SF) and probiotic (P) chewing gums. Material and Methods: Saliva was collected from 12 volunteer dental students at UNESP Sao Jose dos Campos / SP, in order to determine salivary flow (SR) rate and initial buffering capacity (BC). Participants presenting BC>4.0 were invited to continue the research. Participants chewed different types of gum for 3 consecutive days, and saliva was collected at 0-1min, 1-5min, and 5-10min intervals. The time required to neutralize saliva pH after chewing the different types of gum was analyzed by RM ANOVA and Tukey's test (5%). Results: RM ANOVA revealed significant influence on the interaction effect (chewing gum and time) (statisticFdf(4.66) = 4.027, p = 0.0055

Schools are considered to be an optimal space for health education. The meals offered to students are an opportunity for learning and socialization. In this context, the role of the cooks goes beyond the preparation of meals, as they often need to plan the menu and replace some food items. Objective : This study promoted a Professional Development Course with cooks from public schools in Xerem district, in Duque de Caxias, Rio de Janeiro, Brazil, in order to broaden knowledge about healthy eating. Methods: The course was attended by 26 school cooks, and it was taught for four consecutive days in classrooms of the Federal University of Rio de Janeiro, at the Institute of Nutrition Josue de Castro. Previous and later evaluations about knowledge of healthy eating were performed by means of games: the Healthy Dish Game and the Pyramid Food Game. The proposed activities consisted of a lecture, development of educational materials by the participants, and a cooking workshop. The software R and the Shapiro-Wilk tests were used to evaluate if the data has a normal distribution, and the Wilcoxon test (p

O presente trabalho tem como objetivo mostrar a aplicabilidade de kits para monitoramento da qualidade da agua em nascentes. Foram utilizados Ecokit, Kit Potabilidade, e o Colipaper, alem de medicoes com Oximetro, pHmetro e Condutivimetro para medicao de parâmetros como nitrito, nitrato, ferro, oxigenio dissolvido, entre outros. Foram escolhidas para realizacao dos testes tres das nascentes da bacia hidrografica do Arroio do Padre.

Bioactive compounds extracted from natural renewable sources have attracted increased interest from both industry and academia. Cyanobacteria possess a broad range of colored components including carotenoids, chlorophyll, and phycobiliproteins. Phycobiliproteins are pigments accessories photosynthetic potential for use in various applications - dyes in food and cosmetics, fluorescent tags in biomedical research, nutraceutical and pharmaceutical applications. Considerations to obtain of microalgae phycobiliproteins may include: choosing the most suitable method of extraction, solvent and extraction of the main setting parameters. While phycobiliproteins extraction classical methods are reproducible and show good yields are generally time consuming and require the use of elevated temperatures and / or large volumes of solvent, which can cause thermal denaturation or chemical transformation of the products of interest. Therefore, the development of new extraction green techniques permitting the transfer of the results obtained in laboratory scale for industrial need for greater biotechnological exploitation of these and other products from microalgae. In this work, the performance of ionic liquids as solvents in phycobiliproteins extraction from Spirulina (Arthrospira) platensis was evaluated using three different methods: conventional (heating + agitation), microwave and ultrasound. The extraction was optimized using a central composite design and response surface methodology. The effects of temperature, pH, biomass:solvent ratio and power were studied to determine the best extraction conditions of extraction. The results showed that the protic ionic liquids were capable of extracting phycobiliproteins from microalgae, being more efficient than buffer and aprotic ionic liquid [Bmim][Cl]. The effect of pH was more significant in conventional and ultrasound methods. In microwave-assisted extraction, the irradiation power was the most important variable. The allophycocyanin was extracted in larger quantities (13.30 mg.g-1), followed by phycocyanin (10.87 mg.g-1) and phycoerythrin (4.22 mg.g-1). This method of extraction showed advantages over the extraction time, productivity, purity and energy consumption across the conventional method and ultrasound-assisted extraction. The SEM revealed that the microwave caused more impacts on the cellular structure of the microalgae compared to other methods. In the study of operating conditions, microwave-assisted extraction was considered the best technique, using 2-HEAA + 2-HEAF as solvent at power of 62 W, pH 7.0, biomass:solvent ratio 10 mL.g-1 and 2 min of extraction. A savings of 99.94% in electricity consumption was obtained with the use of microwaves compared to conventional method. The extraction method proposed in this work proved to be efficient for obtaining S. platensis phycobiliproteins. By the applied purification methodology the following yield and purity were obtained for phycocyanin, allophycocyanin and phycoerythrin: 15% and 1.22; 11.33% and 1.03; 11.92% and 0.71, respectively. The degree of purity achieved allows the application of these pigments in food and cosmetics. Polyacrylamide gel electrophoresis (SDS-PAGE) showed that the phycobiliproteins have molecular weight around 20 KDa. Preliminary studies on the recovery and reuse of the ionic liquid were conducted, proving the possibility of reuse of these solvents. Compostos bioativos extraídos de fontes naturais renováveis têm atraído o interesse da indústria e da academia. Cianobactérias possuem uma ampla gama de componentes coloridos que incluem carotenoides, clorofila e ficobiliproteínas. Ficobiliproteínas são pigmentos fotossintéticos acessórios com potencial para utilização em diversas aplicações – corantes em alimentos e cosméticos, marcadores fluorescentes em pesquisas biomédicas, aplicações nutracêuticas e farmacêuticas, dentre outras. Considerações sobre a obtenção de ficobiliproteínas de microalgas devem incluir: a escolha do método de extração mais adequado, o tipo de solvente e a definição dos principais parâmetros de extração. Neste trabalho, o desempenho dos líquidos iônicos acetato de N-metil-2-hidroxietilamônio (2-HEAA), formiato de N-metil-2-hidroxietilamônio (2-HEAF), 2-HEAA+2-HEAF (1:1, v/v) e 1-butil-3-metilimidazólio [Bmim][Cl] como solventes na extração de ficobiliproteínas da microalga Spirulina (Arthrospira) platensis foi avaliado por três métodos distintos: convencional (aquecimento+agitação), micro-ondas e ultrassom. O desempenho dos líquidos iônicos foi comparado ao do tampão fosfato de sódio que é o solvente tradicionalmente empregado na extração de ficobiliproteínas. A extração foi otimizada através de um delineamento composto central e pela metodologia de superfície de resposta. Os efeitos da temperatura, do pH, da razão solvente:biomassa e da potência foram estudados para determinar as melhores condições de extração.Os resultados mostraram que os líquidos iônicos próticos foram capazes de extrair as ficobiliproteínas da microalga, tendo sido mais eficientes que o tampão e o líquido iônico aprótico [Bmim][Cl]. O efeito do pH foi o mais significativo na extração convencional e com o ultrassom.Na extração por micro-ondas, a potência da irradiação foi a variável mais influente. A aloficocianina foi o pigmento extraído em maior quantidade (13,30 mg.g-1), seguido da ficocianina (10,87 mg.g-1) e ficoeritrina (4,22 mg.g-1). A extração por micro-ondas apresentou vantagens em relação ao tempo de extração, produtividade, pureza e consumo energético frente ao método convencional e à extração assistida por ultrassom. As imagens obtidas por MEV mostraram que as micro-ondas provocaram mais impactos na estrutura celular da microalga em comparação aos outros métodos. Nas condições de operação do estudo, a extração assistida por micro-ondas foi considerada a melhor técnica, utilizando 2-HEAA+2-HEAF como solvente, potência de 62 W, pH 7,0, razão solvente:biomassa 10 mL.g-1 e 2 minutos de extração.Uma economia de 99,94% no consumo de energia elétrica foi obtida com o uso do micro-ondas em comparação ao método convencional. O método de extração proposto neste trabalho mostrou-se eficiente para a obtenção de ficobiliproteínas de S. platensis. Através da metodologia de purificação aplicada obtiveram-se os seguintes rendimento e pureza para a ficocianina, aloficocianina e ficoeritrina: 15% e 1,22; 11,33% e 1,03; 11,92% e 0,71, respectivamente. O grau de pureza atingido permite a aplicação destes pigmentos em alimentos e cosméticos. A eletroforese em gel de poliacrilamida (SDS-PAGE) mostrou que as ficobiliproteínas têm peso molecular em torno de 20 KDa. Estudos preliminares voltados à recuperação e reutilização do líquido iônico foram conduzidos, comprovando a possibilidade de reaproveitamento destes solventes.