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227 results on '"D'Ercole M"'

2. Concurrent presence of primary hemangioma and breast cancer metastasis within a lymph node: a case report inspired by the legacy of Professor Juan Rosai

Author

Ivanova, M, D'Ercole, M, Porta, F, Di Venosa, B, Frascarelli, C, Di Bella, C, Pagni, F, Guerini-Rocco, E, Fusco, N, Ivanova, Mariia, D'Ercole, Marianna, Porta, Francesca Maria, Di Venosa, Benedetta, Frascarelli, Chiara, Di Bella, Camillo, Pagni, Fabio, Guerini-Rocco, Elena, Fusco, Nicola, Ivanova, M, D'Ercole, M, Porta, F, Di Venosa, B, Frascarelli, C, Di Bella, C, Pagni, F, Guerini-Rocco, E, Fusco, N, Ivanova, Mariia, D'Ercole, Marianna, Porta, Francesca Maria, Di Venosa, Benedetta, Frascarelli, Chiara, Di Bella, Camillo, Pagni, Fabio, Guerini-Rocco, Elena, and Fusco, Nicola

Abstract

Secondary neoplastic lesions in lymph nodes are predominantly metastases from solid tumors, whereas primary lymph node hemangiomas are exceptionally uncommon, with only 24 well-documented cases in the literature. Histologically, they are characterized by endothelial cells that may appear flattened or enlarged, with variable vascular density, and the presence of stromal elements. Notably, the concurrent presence of a primary hemangioma and a metastasis from breast cancer – the latter being the most prevalent secondary lesion in axillary lymph nodes – represents an unprecedented observation. The unique case presented herein underscores the exceptional rarity of primary lymph node hemangiomas and demonstrates for the first time their possible coexistence with breast cancer metastasis within the same axillary lymph node. In sharing and discussing this case study, we pay homage to Professor Juan Rosai, whose work in redefining rare and complex diagnoses continues to enlighten our understanding of lymph node vascular lesions.

Published
2024

6. Intraoperative Corticobulbar Motor Evoked Potential in Cerebellopontine Angle Surgery: A Clinically Meaningful Tool to Predict Early and Late Facial Nerve Recovery

Author

Della Pepa, Giuseppe Maria, Stifano, V, D'Alessandris, Qg, Menna, G, Burattini, B, Di Domenico, M, Izzo, A, D'Ercole, M, Lauretti, L, Olivi, A, Montano, N, Della Pepa GM (ORCID:0000-0001-8698-3359), Stifano V, D'Alessandris QG, Menna G, Burattini B, Di Domenico M, Izzo A, D'Ercole M, Lauretti L (ORCID:0000-0002-6463-055X), Olivi A (ORCID:0000-0002-4489-7564), Montano N (ORCID:0000-0002-4965-1950), Della Pepa, Giuseppe Maria, Stifano, V, D'Alessandris, Qg, Menna, G, Burattini, B, Di Domenico, M, Izzo, A, D'Ercole, M, Lauretti, L, Olivi, A, Montano, N, Della Pepa GM (ORCID:0000-0001-8698-3359), Stifano V, D'Alessandris QG, Menna G, Burattini B, Di Domenico M, Izzo A, D'Ercole M, Lauretti L (ORCID:0000-0002-6463-055X), Olivi A (ORCID:0000-0002-4489-7564), and Montano N (ORCID:0000-0002-4965-1950)

Abstract

Background: Intraoperative neuromonitoring is crucial for facial nerve preservation in cerebellopontine angle (CPA) surgery. Among the available techniques, the role of intraoperative corticobulbar facial motor evoked potentials (FMEPs) is unclear. Objective: To evaluate the significance of intraoperative FMEPs as indicators for early and late postoperative facial nerve function (FNF) in CPA tumor resection and the feasibility of their integration with standard monitoring techniques. Methods: An institutional series of 83 patients who underwent surgery under intraoperative monitoring for CPA extra-axial tumor resection was reported. A pair of needle electrodes was used to record FMEP from orbicularis oculi (OOc) and orbicularis oris (OOr) muscles at baseline, at the end of surgery and minimum values recorded. From FMEP amplitudes, minimum-to-baseline amplitude ratio (MBR), final-to-baseline amplitude ratio (FBR), and recovery value, intended as FBR minus MBR, were calculated. These indices were correlated with early and late postoperative FNF. Results: Our analysis demonstrated that higher FBR (both from OOc and OOr) and MBR (from OOr only) were associated with a good early and late FNF; a higher MBR from OOc was significantly associated with a good late FNF. The most accurate index in predicting early FNF was FBR measured from OOr with a cutoff of 35.56%, whereas the most accurate index in predicting late FNF was FBR as measured from OOc with a cutoff of 14.29%. Conclusion: Our study confirmed that FMEPs are reliable predictors of early and late postoperative FNF in CPA surgery and could be easily integrated with standard intraoperative neuromonitoring techniques.

Published
2022

7. Tailored Approach and Multimodal Intraoperative Neuromonitoring in Cerebellopontine Angle Surgery

Author

Izzo, A., Stifano, V., Della Pepa, G. M., Di Domenico, M., D'Alessandris, Q. G., Menna, G., D'Ercole, M., Lauretti, L., Olivi, A., Montano, N., Stifano V., Della Pepa G. M. (ORCID:0000-0001-8698-3359), D'Alessandris Q. G. (ORCID:0000-0002-2953-9291), Menna G., D'Ercole M., Lauretti L. (ORCID:0000-0002-6463-055X), Olivi A. (ORCID:0000-0002-4489-7564), Montano N. (ORCID:0000-0002-4965-1950), Izzo, A., Stifano, V., Della Pepa, G. M., Di Domenico, M., D'Alessandris, Q. G., Menna, G., D'Ercole, M., Lauretti, L., Olivi, A., Montano, N., Stifano V., Della Pepa G. M. (ORCID:0000-0001-8698-3359), D'Alessandris Q. G. (ORCID:0000-0002-2953-9291), Menna G., D'Ercole M., Lauretti L. (ORCID:0000-0002-6463-055X), Olivi A. (ORCID:0000-0002-4489-7564), and Montano N. (ORCID:0000-0002-4965-1950)

Abstract

The cerebellopontine angle (CPA) is a highly complex anatomical compartment consisting of numerous nervous and vascular structures that present mutual and intricate spatial relationships. CPA surgery represents, therefore, a constant challenge for neurosurgeons. Over the years, neurosurgeons have developed and refined several solutions with the aim of maximizing the surgical treatment effects while minimizing the invasiveness and risks for the patient. In this paper, we present our integrated approach to CPA surgery, describing its advantages in treating pathologies in this anatomical district. Our approach incorporates the use of technology, such as neuronavigation, along with advanced and multimodal intraoperative neuromonitoring (IONM) techniques, with the final goal of making this surgery safe and effective.

Published
2022

9. A Study on the Role of Intraoperative Corticobulbar Motor Evoked Potentials for Improving Safety of Cerebellopontine Angle Surgery in Elderly Patients

Author

D'Alessandris, Quintino Giorgio, Menna, Grazia, Stifano, Vito, Della Pepa, Giuseppe Maria, Burattini, Benedetta, Di Domenico, M., Izzo, A., D'Ercole, Manuela, Lauretti, Liverana, Montano, Nicola, Olivi, Alessandro, D'Alessandris Q. G. (ORCID:0000-0002-2953-9291), Menna G., Stifano V., Della Pepa G. M. (ORCID:0000-0001-8698-3359), Burattini B., D'Ercole M., Lauretti L. (ORCID:0000-0002-6463-055X), Montano N. (ORCID:0000-0002-4965-1950), Olivi A. (ORCID:0000-0002-4489-7564), D'Alessandris, Quintino Giorgio, Menna, Grazia, Stifano, Vito, Della Pepa, Giuseppe Maria, Burattini, Benedetta, Di Domenico, M., Izzo, A., D'Ercole, Manuela, Lauretti, Liverana, Montano, Nicola, Olivi, Alessandro, D'Alessandris Q. G. (ORCID:0000-0002-2953-9291), Menna G., Stifano V., Della Pepa G. M. (ORCID:0000-0001-8698-3359), Burattini B., D'Ercole M., Lauretti L. (ORCID:0000-0002-6463-055X), Montano N. (ORCID:0000-0002-4965-1950), and Olivi A. (ORCID:0000-0002-4489-7564)

Abstract

Preservation of facial nerve function (FNF) during neurosurgery for cerebellopontine angle (CPA) tumors is paramount in elderly patients. Corticobulbar facial motor evoked potentials (FMEPs) allow assessment intraoperatively of the functional integrity of facial motor pathways, thus improving safety. We aimed to evaluate the significance of intraoperative FMEPs in patients 65 years and older. A retrospective cohort of 35 patients undergoing CPA tumors resection was reported; outcomes of patients aged 65–69 years vs. ≥70 years were compared. FMEPs were registered both from upper and lower face muscles, and amplitude ratios (minimum-to-baseline, MBR; final-to-baseline, FBR; and recovery value, FBR minus MBR) were calculated. Overall, 78.8% of patients had a good late (at 1 year) FNF, with no differences between age groups. In patients aged ≥70 years, MBR significantly correlated with late FNF. At receiver operating characteristics (ROC) analysis, in patients aged 65–69 years, FBR (with 50% cut-off value) could reliably predict late FNF. By contrast, in patients aged ≥70 years, the most accurate predictor of late FNF was MBR, with 12.5% cut-off. Thus, FMEPs are a valuable tool for improving safety in CPA surgery in elderly patients as well. Considering literature data, we noticed higher cut-off values for FBR and a role for MBR, which suggests an increased vulnerability of facial nerves in elderly patients compared to younger ones.

Published
2023

10. Neuromodulation for Brain Tumors: Myth or Reality? A Narrative Review

Author

D'Alessandris, Quintino Giorgio, Menna, Grazia, Izzo, A., D'Ercole, Manuela, Della Pepa, Giuseppe Maria, Lauretti, Liverana, Pallini, Roberto, Olivi, Alessandro, Montano, Nicola, D'Alessandris Q. G. (ORCID:0000-0002-2953-9291), Menna G., D'Ercole M., Della Pepa G. M. (ORCID:0000-0001-8698-3359), Lauretti L. (ORCID:0000-0002-6463-055X), Pallini R. (ORCID:0000-0002-4611-8827), Olivi A. (ORCID:0000-0002-4489-7564), Montano N. (ORCID:0000-0002-4965-1950), D'Alessandris, Quintino Giorgio, Menna, Grazia, Izzo, A., D'Ercole, Manuela, Della Pepa, Giuseppe Maria, Lauretti, Liverana, Pallini, Roberto, Olivi, Alessandro, Montano, Nicola, D'Alessandris Q. G. (ORCID:0000-0002-2953-9291), Menna G., D'Ercole M., Della Pepa G. M. (ORCID:0000-0001-8698-3359), Lauretti L. (ORCID:0000-0002-6463-055X), Pallini R. (ORCID:0000-0002-4611-8827), Olivi A. (ORCID:0000-0002-4489-7564), and Montano N. (ORCID:0000-0002-4965-1950)

Abstract

In recent years, research on brain cancers has turned towards the study of the interplay between the tumor and its host, the normal brain. Starting from the establishment of a parallelism between neurogenesis and gliomagenesis, the influence of neuronal activity on the development of brain tumors, particularly gliomas, has been partially unveiled. Notably, direct electrochemical synapses between neurons and glioma cells have been identified, paving the way for new approaches for the cure of brain cancers. Since this novel field of study has been defined “cancer neuroscience”, anticancer therapeutic approaches exploiting these discoveries can be referred to as “cancer neuromodulation”. In the present review, we provide an up-to-date description of the novel findings and of the therapeutic neuromodulation perspectives in cancer neuroscience. We focus both on more traditional oncologic approaches, aimed at modulating the major pathways involved in cancer neuroscience through drugs or genetic engineering techniques, and on electric stimulation proposals; the latter is at the cutting-edge of neuro-oncology.

Published
2023

11. The importance of pre-operative neuroanatomical study in the surgical treatment of trigeminal neuralgia associated with multiple sclerosis

Author

Montano, Nicola, Rapisarda, A., D'Alessandris, Quintino Giorgio, D'Ercole, Manuela, Izzo, A., Montano N. (ORCID:0000-0002-4965-1950), D'Alessandris Q. G. (ORCID:0000-0002-2953-9291), D'Ercole M., Montano, Nicola, Rapisarda, A., D'Alessandris, Quintino Giorgio, D'Ercole, Manuela, Izzo, A., Montano N. (ORCID:0000-0002-4965-1950), D'Alessandris Q. G. (ORCID:0000-0002-2953-9291), and D'Ercole M.

Abstract

N/A

Published
2023

13. Management of intracranial hypertension following traumatic brain injury: A best clinical practice adoption proposal for intracranial pressure monitoring and decompressive craniectomy: Joint statements by the Traumatic Brain Injury Section of the Italian Society of Neurosurgery (SINch) and the Neuroanesthesia and Neurocritical Care Study Group of the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI)

Author

Iaccarino, C, Lippa, L, Munari, M, Castioni, C, Robba, C, Caricato, A, Pompucci, A, Signoretti, S, Zona, G, Rasulo, F, Aimar, E, Amato, S, Angileri, F, Anile, C, Assietti, R, Baratto, V, Barbanera, A, Basile, L, Battaglia, R, Bellocchi, S, Bertuccio, A, Blanco, S, Bolognini, A, Boniferro, B, Bordi, L, Bortolotti, C, Brandini, V, Broger, M, Brollo, M, Caffarella, D, Caggiano, C, Cantisani, P, Capone, C, Cappelletto, B, Capuano, C, Carangelo, B, Caruselli, G, Chessa, M, Chiara, M, Chibbaro, S, Cioffi, V, Ciprianocecchi, P, Colistra, D, Conti, C, Contratti, F, Costella, G, Cuoci, A, D'Avella, D, D'Ercole, M, Deangelis, M, Defalco, R, de Luca, G, de Marinis, P, Del Vecchio, C, Delfinis, C, Denaro, L, Deodato, F, Desogus, N, Disomma, A, Domenicucci, M, Dones, F, Fina, M, Fiori, L, Fricia, M, Gaetani, P, Gazzeri, R, Gentile, M, Germano, A, Ghadirpour, R, Gianfreda, C, Gigante, N, Gigli, R, Giorgetti, J, Giusa, M, Gravina, U, Grippi, L, Guida, F, Guizzardi, G, Iannuzzo, G, Kropp, M, Lattanzi, L, Lucantoni, D, Maffei, L, Magliulo, M, Marconi, F, Marruzzo, D, Martellotta, N, Marton, E, Maugeri, R, Mauro, G, Meli, F, Menniti, A, Merciadri, P, Milanese, L, Nardacci, B, Nasi, D, Orvieto, P, Pacca, P, Pansini, G, Panzarasa, G, Passanisi, M, Pavesi, G, Pizzoni, C, Pulera, F, Rapana, A, Ricci, A, Rispoli, R, Rotondo, M, Russo, N, Santilli, S, Scarano, E, Schwarz, A, Servadei, F, Simonetti, G, Stefini, R, Talamonti, G, Turrisi, A, Valente, V, Villa, A, Vindigni, M, Visocchi, M, Vitali, M, Wierzbicki, V, Zambon, G, Zanotti, B, Zenga, F, Alampi, D, Alessandri, F, Aloj, F, Amigoni, A, Aspide, R, Bertuetti, R, Betti, V, Bilotta, F, Bonato, V, Bosco, E, Brita, M, Buscema, G, Cafiero, T, Cappuccio, D, Caradonna, M, Caria, C, Casartelliliviero, M, Ciritella, P, Cirrincione, S, Citerio, G, Colelli, S, Coletta, F, Concordia, L, Congedo, E, Covotta, M, Crimella, F, Dall'Acqua, G, De Cassai, A, Defulviis, S, Deperi, E, Deana, C, Delgaudio, A, Denittis, N, Dicolandrea, S, Divezza, F, Ferri, F, Flocco, R, Fontana, C, Forastierimolinari, A, Frangiosa, A, Fumagalli, P, Fuselli, E, Garbarino, M, Gelormini, D, Geraci, C, Geraldini, F, Giacomucci, A, Giampaoli, V, Giorgetti, D, Gritti, P, Gualdani, S, Iacovazzo, C, Iermano, C, Latronico, N, Lugari, S, Lusenti, F, Maglione, C, Magnoni, S, Maiarota, F, Malla, M, Marchesi, M, Martino, C, Matteotti, I, Mazzeo, A, Morello, G, Nardiello, I, Paticchio, F, Pegoli, M, Perotti, V, Piazzolla, M, Picciafuochi, F, Rachedi, N, Radolovich, D, Recchia, A, Riccardi, S, Romagnoli, S, Sala, S, Scafuro, M, Sgarlata, P, Soragni, A, Stefani, F, Stival, E, Stofella, G, Terranova, F, Tinturini, R, Togni, T, Toto, R, Trapani, D, Tringali, E, Tullo, L, Valente, A, Valeo, T, Varelli, G, Villani, R, Zamacavicchi, F, Zanello, M, Zarrillo, N, Zugni, N, Iaccarino C., Lippa L., Munari M., Castioni C. A., Robba C., Caricato A., Pompucci A., Signoretti S., Zona G., Rasulo F. A., Aimar E., Amato S., Angileri F. F., Anile C., Assietti R., Baratto V., Barbanera A., Basile L., Battaglia R., Bellocchi S., Bertuccio A., Blanco S., Bolognini A., Boniferro B., Bordi L., Bortolotti C., Brandini V., Broger M., Brollo M., Caffarella D. D., Caggiano C., Cantisani P. L., Capone C., Cappelletto B., Capuano C., Carangelo B., Caruselli G., Chessa M. A., Chiara M., Chibbaro S., Cioffi V., Ciprianocecchi P., Colistra D., Conti C., Contratti F., Costella G. B., Cuoci A., D'Avella D., D'Ercole M., Deangelis M., Defalco R., de Luca G., de Marinis P., Del Vecchio C., Delfinis C., Denaro L., Deodato F., Desogus N., Disomma A., Domenicucci M., Dones F., Fina M., Fiori L., Fricia M., Gaetani P., Gazzeri R., Gentile M., Germano A., Ghadirpour R., Gianfreda C. D., Gigante N., Gigli R., Giorgetti J., Giusa M., Gravina U. G., Grippi L., Guida F., Guizzardi G., Iannuzzo G., Kropp M., Lattanzi L., Lucantoni D., Maffei L., Magliulo M., Marconi F., Marruzzo D., Martellotta N., Marton E., Maugeri R., Mauro G., Meli F., Menniti A., Merciadri P., Milanese L., Nardacci B., Nasi D., Orvieto P., Pacca P., Pansini G., Panzarasa G., Passanisi M., Pavesi G., Pizzoni C., Pulera F., Rapana A., Ricci A., Rispoli R., Rotondo M., Russo N., Santilli S., Scarano E., Schwarz A., Servadei F., Simonetti G., Stefini R., Talamonti G., Turrisi A., Valente V. M., Villa A., Vindigni M., Visocchi M., Vitali M., Wierzbicki V., Zambon G., Zanotti B., Zenga F., Alampi D., Alessandri F., Aloj F., Amigoni A., Aspide R., Bertuetti R., Betti V., Bilotta F., Bonato V., Bosco E., Brita M., Buscema G., Cafiero T., Cappuccio D., Caradonna M., Caria C. G., Casartelliliviero M., Ciritella P., Cirrincione S., Citerio G., Colelli S., Coletta F., Concordia L., Congedo E., Covotta M., Crimella F., Dall'Acqua G., De Cassai A., Defulviis S., Deperi E., Deana C., Delgaudio A., Denittis N., Dicolandrea S., Divezza F., Ferri F., Flocco R., Fontana C., Forastierimolinari A., Frangiosa A., Fumagalli P., Fuselli E., Garbarino M. M., Gelormini D., Geraci C., Geraldini F., Giacomucci A., Giampaoli V., Giorgetti D., Gritti P., Gualdani S., Iacovazzo C., Iermano C., Latronico N., Lugari S., Lusenti F., Maglione C., Magnoni S., Maiarota F., Malla M., Marchesi M., Martino C., Matteotti I., Mazzeo A. T., Morello G., Nardiello I., Paticchio F., Pegoli M., Perotti V., Piazzolla M., Picciafuochi F., Rachedi N., Radolovich D. K., Recchia A., Riccardi S., Romagnoli S., Sala S., Scafuro M. A., Sgarlata P., Soragni A., Stefani F., Stival E., Stofella G., Terranova F., Tinturini R., Togni T., Toto R., Trapani D., Tringali E., Tullo L., Valente A., Valeo T., Varelli G., Villani R., Zamacavicchi F., Zanello M., Zarrillo N., Zugni N., Iaccarino, C, Lippa, L, Munari, M, Castioni, C, Robba, C, Caricato, A, Pompucci, A, Signoretti, S, Zona, G, Rasulo, F, Aimar, E, Amato, S, Angileri, F, Anile, C, Assietti, R, Baratto, V, Barbanera, A, Basile, L, Battaglia, R, Bellocchi, S, Bertuccio, A, Blanco, S, Bolognini, A, Boniferro, B, Bordi, L, Bortolotti, C, Brandini, V, Broger, M, Brollo, M, Caffarella, D, Caggiano, C, Cantisani, P, Capone, C, Cappelletto, B, Capuano, C, Carangelo, B, Caruselli, G, Chessa, M, Chiara, M, Chibbaro, S, Cioffi, V, Ciprianocecchi, P, Colistra, D, Conti, C, Contratti, F, Costella, G, Cuoci, A, D'Avella, D, D'Ercole, M, Deangelis, M, Defalco, R, de Luca, G, de Marinis, P, Del Vecchio, C, Delfinis, C, Denaro, L, Deodato, F, Desogus, N, Disomma, A, Domenicucci, M, Dones, F, Fina, M, Fiori, L, Fricia, M, Gaetani, P, Gazzeri, R, Gentile, M, Germano, A, Ghadirpour, R, Gianfreda, C, Gigante, N, Gigli, R, Giorgetti, J, Giusa, M, Gravina, U, Grippi, L, Guida, F, Guizzardi, G, Iannuzzo, G, Kropp, M, Lattanzi, L, Lucantoni, D, Maffei, L, Magliulo, M, Marconi, F, Marruzzo, D, Martellotta, N, Marton, E, Maugeri, R, Mauro, G, Meli, F, Menniti, A, Merciadri, P, Milanese, L, Nardacci, B, Nasi, D, Orvieto, P, Pacca, P, Pansini, G, Panzarasa, G, Passanisi, M, Pavesi, G, Pizzoni, C, Pulera, F, Rapana, A, Ricci, A, Rispoli, R, Rotondo, M, Russo, N, Santilli, S, Scarano, E, Schwarz, A, Servadei, F, Simonetti, G, Stefini, R, Talamonti, G, Turrisi, A, Valente, V, Villa, A, Vindigni, M, Visocchi, M, Vitali, M, Wierzbicki, V, Zambon, G, Zanotti, B, Zenga, F, Alampi, D, Alessandri, F, Aloj, F, Amigoni, A, Aspide, R, Bertuetti, R, Betti, V, Bilotta, F, Bonato, V, Bosco, E, Brita, M, Buscema, G, Cafiero, T, Cappuccio, D, Caradonna, M, Caria, C, Casartelliliviero, M, Ciritella, P, Cirrincione, S, Citerio, G, Colelli, S, Coletta, F, Concordia, L, Congedo, E, Covotta, M, Crimella, F, Dall'Acqua, G, De Cassai, A, Defulviis, S, Deperi, E, Deana, C, Delgaudio, A, Denittis, N, Dicolandrea, S, Divezza, F, Ferri, F, Flocco, R, Fontana, C, Forastierimolinari, A, Frangiosa, A, Fumagalli, P, Fuselli, E, Garbarino, M, Gelormini, D, Geraci, C, Geraldini, F, Giacomucci, A, Giampaoli, V, Giorgetti, D, Gritti, P, Gualdani, S, Iacovazzo, C, Iermano, C, Latronico, N, Lugari, S, Lusenti, F, Maglione, C, Magnoni, S, Maiarota, F, Malla, M, Marchesi, M, Martino, C, Matteotti, I, Mazzeo, A, Morello, G, Nardiello, I, Paticchio, F, Pegoli, M, Perotti, V, Piazzolla, M, Picciafuochi, F, Rachedi, N, Radolovich, D, Recchia, A, Riccardi, S, Romagnoli, S, Sala, S, Scafuro, M, Sgarlata, P, Soragni, A, Stefani, F, Stival, E, Stofella, G, Terranova, F, Tinturini, R, Togni, T, Toto, R, Trapani, D, Tringali, E, Tullo, L, Valente, A, Valeo, T, Varelli, G, Villani, R, Zamacavicchi, F, Zanello, M, Zarrillo, N, Zugni, N, Iaccarino C., Lippa L., Munari M., Castioni C. A., Robba C., Caricato A., Pompucci A., Signoretti S., Zona G., Rasulo F. A., Aimar E., Amato S., Angileri F. F., Anile C., Assietti R., Baratto V., Barbanera A., Basile L., Battaglia R., Bellocchi S., Bertuccio A., Blanco S., Bolognini A., Boniferro B., Bordi L., Bortolotti C., Brandini V., Broger M., Brollo M., Caffarella D. D., Caggiano C., Cantisani P. L., Capone C., Cappelletto B., Capuano C., Carangelo B., Caruselli G., Chessa M. A., Chiara M., Chibbaro S., Cioffi V., Ciprianocecchi P., Colistra D., Conti C., Contratti F., Costella G. B., Cuoci A., D'Avella D., D'Ercole M., Deangelis M., Defalco R., de Luca G., de Marinis P., Del Vecchio C., Delfinis C., Denaro L., Deodato F., Desogus N., Disomma A., Domenicucci M., Dones F., Fina M., Fiori L., Fricia M., Gaetani P., Gazzeri R., Gentile M., Germano A., Ghadirpour R., Gianfreda C. D., Gigante N., Gigli R., Giorgetti J., Giusa M., Gravina U. G., Grippi L., Guida F., Guizzardi G., Iannuzzo G., Kropp M., Lattanzi L., Lucantoni D., Maffei L., Magliulo M., Marconi F., Marruzzo D., Martellotta N., Marton E., Maugeri R., Mauro G., Meli F., Menniti A., Merciadri P., Milanese L., Nardacci B., Nasi D., Orvieto P., Pacca P., Pansini G., Panzarasa G., Passanisi M., Pavesi G., Pizzoni C., Pulera F., Rapana A., Ricci A., Rispoli R., Rotondo M., Russo N., Santilli S., Scarano E., Schwarz A., Servadei F., Simonetti G., Stefini R., Talamonti G., Turrisi A., Valente V. M., Villa A., Vindigni M., Visocchi M., Vitali M., Wierzbicki V., Zambon G., Zanotti B., Zenga F., Alampi D., Alessandri F., Aloj F., Amigoni A., Aspide R., Bertuetti R., Betti V., Bilotta F., Bonato V., Bosco E., Brita M., Buscema G., Cafiero T., Cappuccio D., Caradonna M., Caria C. G., Casartelliliviero M., Ciritella P., Cirrincione S., Citerio G., Colelli S., Coletta F., Concordia L., Congedo E., Covotta M., Crimella F., Dall'Acqua G., De Cassai A., Defulviis S., Deperi E., Deana C., Delgaudio A., Denittis N., Dicolandrea S., Divezza F., Ferri F., Flocco R., Fontana C., Forastierimolinari A., Frangiosa A., Fumagalli P., Fuselli E., Garbarino M. M., Gelormini D., Geraci C., Geraldini F., Giacomucci A., Giampaoli V., Giorgetti D., Gritti P., Gualdani S., Iacovazzo C., Iermano C., Latronico N., Lugari S., Lusenti F., Maglione C., Magnoni S., Maiarota F., Malla M., Marchesi M., Martino C., Matteotti I., Mazzeo A. T., Morello G., Nardiello I., Paticchio F., Pegoli M., Perotti V., Piazzolla M., Picciafuochi F., Rachedi N., Radolovich D. K., Recchia A., Riccardi S., Romagnoli S., Sala S., Scafuro M. A., Sgarlata P., Soragni A., Stefani F., Stival E., Stofella G., Terranova F., Tinturini R., Togni T., Toto R., Trapani D., Tringali E., Tullo L., Valente A., Valeo T., Varelli G., Villani R., Zamacavicchi F., Zanello M., Zarrillo N., and Zugni N.

Abstract

No robust evidence is provided by literature regarding the management of intracranial hypertension following severe traumatic brain injury (TBI). This is mostly due to the lack of prospective randomized controlled trials (RCTs), the presence of studies containing extreme heterogeneously collected populations and controversial considerations about chosen outcome. A scientific society should provide guidelines for care management and scientific support for those areas for which evidence-based medicine has not been identified. However, RCTs in severe TBI have failed to establish intervention effectiveness, arising the need to make greater use of tools such as Consensus Conferences between experts, which have the advantage of providing recommendations based on experience, on the analysis of updated literature data and on the direct comparison of different logistic realities. The Italian scientific societies should provide guidelines following the national laws ruling the best medical practice. However, many limitations do not allow the collection of data supporting high levels of evidence for intracranial pressure (ICP) monitoring and decompressive craniectomy (DC) in patients with severe TBI. This intersociety document proposes best practice guidelines for this subsetting of patients to be adopted on a national Italian level, along with joint statements from “TBI Section” of the Italian Society of Neurosurgery (SINch) endorsed by the Neuroanesthesia and Neurocritical Care Study Group of the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI). Presented here is a recap of recommendations on management of ICP and DC supported a high level of available evidence and rate of agreement expressed by the assemblies during the more recent consensus conferences, where members of both groups have had a role of active participants and supporters. The listed recommendations have been sent to a panel of experts consisting of the 107 members of the “T

Published
2021

14. Management of intracranial hypertension following traumatic brain injury: a best clinical practice adoption proposal for intracranial pressure monitoring and decompressive craniectomy. Joint statements by the Traumatic Brain Injury Section of the Italian Society of Neurosurgery (SINch) and the Neuroanesthesia and Neurocritical Care Study Group of the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI)

Author

Iaccarino C., Lippa L., Munari M., Castioni C. A., Robba C., Caricato A., Pompucci A., Signoretti S., Zona G., Rasulo F. A., Aimar E., Amato S., Angileri F. F., Anile C., Assietti R., Baratto V., Barbanera A., Basile L., Battaglia R., Bellocchi S., Bertuccio A., Blanco S., Bolognini A., Boniferro B., Bordi L., Bortolotti C., Brandini V., Broger M., Brollo M., Caffarella D. D., Caggiano C., Cantisani P. L., Capone C., Cappelletto B., Capuano C., Carangelo B., Caruselli G., Chessa M. A., Chiara M., Chibbaro S., Cioffi V., Ciprianocecchi P., Colistra D., Conti C., Contratti F., Costella G. B., Cuoci A., D'Avella D., D'Ercole M., Deangelis M., Defalco R., de Luca G., de Marinis P., Del Vecchio C., Delfinis C., Denaro L., Deodato F., Desogus N., Disomma A., Domenicucci M., Dones F., Fina M., Fiori L., Fricia M., Gaetani P., Gazzeri R., Gentile M., Germano A., Ghadirpour R., Gianfreda C. D., Gigante N., Gigli R., Giorgetti J., Giusa M., Gravina U. G., Grippi L., Guida F., Guizzardi G., Iannuzzo G., Kropp M., Lattanzi L., Lucantoni D., Maffei L., Magliulo M., Marconi F., Marruzzo D., Martellotta N., Marton E., Maugeri R., Mauro G., Meli F., Menniti A., Merciadri P., Milanese L., Nardacci B., Nasi D., Orvieto P., Pacca P., Pansini G., Panzarasa G., Passanisi M., Pavesi G., Pizzoni C., Pulera F., Rapana A., Ricci A., Rispoli R., Rotondo M., Russo N., Santilli S., Scarano E., Schwarz A., Servadei F., Simonetti G., Stefini R., Talamonti G., Turrisi A., Valente V. M., Villa A., Vindigni M., Visocchi M., Vitali M., Wierzbicki V., Zambon G., Zanotti B., Zenga F., Alampi D., Alessandri F., Aloj F., Amigoni A., Aspide R., Bertuetti R., Betti V., Bilotta F., Bonato V., Bosco E., Brita M., Buscema G., Cafiero T., Cappuccio D., Caradonna M., Caria C. G., Casartelliliviero M., Ciritella P., Cirrincione S., Citerio G., Colelli S., Coletta F., Concordia L., Congedo E., Covotta M., Crimella F., Dall'Acqua G., De Cassai A., Defulviis S., Deperi E., Deana C., Delgaudio A., Denittis N., Dicolandrea S., Divezza F., Ferri F., Flocco R., Fontana C., Forastierimolinari A., Frangiosa A., Fumagalli P., Fuselli E., Garbarino M. M., Gelormini D., Geraci C., Geraldini F., Giacomucci A., Giampaoli V., Giorgetti D., Gritti P., Gualdani S., Iacovazzo C., Iermano C., Latronico N., Lugari S., Lusenti F., Maglione C., Magnoni S., Maiarota F., Malla M., Marchesi M., Martino C., Matteotti I., Mazzeo A. T., Morello G., Nardiello I., Paticchio F., Pegoli M., Perotti V., Piazzolla M., Picciafuochi F., Rachedi N., Radolovich D. K., Recchia A., Riccardi S., Romagnoli S., Sala S., Scafuro M. A., Sgarlata P., Soragni A., Stefani F., Stival E., Stofella G., Terranova F., Tinturini R., Togni T., Toto R., Trapani D., Tringali E., Tullo L., Valente A., Valeo T., Varelli G., Villani R., Zamacavicchi F., Zanello M., Zarrillo N., Zugni N., Iaccarino, C, Lippa, L, Munari, M, Castioni, C, Robba, C, Caricato, A, Pompucci, A, Signoretti, S, Zona, G, Rasulo, F, Aimar, E, Amato, S, Angileri, F, Anile, C, Assietti, R, Baratto, V, Barbanera, A, Basile, L, Battaglia, R, Bellocchi, S, Bertuccio, A, Blanco, S, Bolognini, A, Boniferro, B, Bordi, L, Bortolotti, C, Brandini, V, Broger, M, Brollo, M, Caffarella, D, Caggiano, C, Cantisani, P, Capone, C, Cappelletto, B, Capuano, C, Carangelo, B, Caruselli, G, Chessa, M, Chiara, M, Chibbaro, S, Cioffi, V, Ciprianocecchi, P, Colistra, D, Conti, C, Contratti, F, Costella, G, Cuoci, A, D'Avella, D, D'Ercole, M, Deangelis, M, Defalco, R, de Luca, G, de Marinis, P, Del Vecchio, C, Delfinis, C, Denaro, L, Deodato, F, Desogus, N, Disomma, A, Domenicucci, M, Dones, F, Fina, M, Fiori, L, Fricia, M, Gaetani, P, Gazzeri, R, Gentile, M, Germano, A, Ghadirpour, R, Gianfreda, C, Gigante, N, Gigli, R, Giorgetti, J, Giusa, M, Gravina, U, Grippi, L, Guida, F, Guizzardi, G, Iannuzzo, G, Kropp, M, Lattanzi, L, Lucantoni, D, Maffei, L, Magliulo, M, Marconi, F, Marruzzo, D, Martellotta, N, Marton, E, Maugeri, R, Mauro, G, Meli, F, Menniti, A, Merciadri, P, Milanese, L, Nardacci, B, Nasi, D, Orvieto, P, Pacca, P, Pansini, G, Panzarasa, G, Passanisi, M, Pavesi, G, Pizzoni, C, Pulera, F, Rapana, A, Ricci, A, Rispoli, R, Rotondo, M, Russo, N, Santilli, S, Scarano, E, Schwarz, A, Servadei, F, Simonetti, G, Stefini, R, Talamonti, G, Turrisi, A, Valente, V, Villa, A, Vindigni, M, Visocchi, M, Vitali, M, Wierzbicki, V, Zambon, G, Zanotti, B, Zenga, F, Alampi, D, Alessandri, F, Aloj, F, Amigoni, A, Aspide, R, Bertuetti, R, Betti, V, Bilotta, F, Bonato, V, Bosco, E, Brita, M, Buscema, G, Cafiero, T, Cappuccio, D, Caradonna, M, Caria, C, Casartelliliviero, M, Ciritella, P, Cirrincione, S, Citerio, G, Colelli, S, Coletta, F, Concordia, L, Congedo, E, Covotta, M, Crimella, F, Dall'Acqua, G, De Cassai, A, Defulviis, S, Deperi, E, Deana, C, Delgaudio, A, Denittis, N, Dicolandrea, S, Divezza, F, Ferri, F, Flocco, R, Fontana, C, Forastierimolinari, A, Frangiosa, A, Fumagalli, P, Fuselli, E, Garbarino, M, Gelormini, D, Geraci, C, Geraldini, F, Giacomucci, A, Giampaoli, V, Giorgetti, D, Gritti, P, Gualdani, S, Iacovazzo, C, Iermano, C, Latronico, N, Lugari, S, Lusenti, F, Maglione, C, Magnoni, S, Maiarota, F, Malla, M, Marchesi, M, Martino, C, Matteotti, I, Mazzeo, A, Morello, G, Nardiello, I, Paticchio, F, Pegoli, M, Perotti, V, Piazzolla, M, Picciafuochi, F, Rachedi, N, Radolovich, D, Recchia, A, Riccardi, S, Romagnoli, S, Sala, S, Scafuro, M, Sgarlata, P, Soragni, A, Stefani, F, Stival, E, Stofella, G, Terranova, F, Tinturini, R, Togni, T, Toto, R, Trapani, D, Tringali, E, Tullo, L, Valente, A, Valeo, T, Varelli, G, Villani, R, Zamacavicchi, F, Zanello, M, Zarrillo, N, Zugni, N, Iaccarino, C., Lippa, L., Munari, M., Castioni, C. A., Robba, C., Caricato, A., Pompucci, A., Signoretti, S., Zona, G., Rasulo, F. A., Aimar, E., Amato, S., Angileri, F. F., Anile, C., Assietti, R., Baratto, V., Barbanera, A., Basile, L., Battaglia, R., Bellocchi, S., Bertuccio, A., Blanco, S., Bolognini, A., Boniferro, B., Bordi, L., Bortolotti, C., Brandini, V., Broger, M., Brollo, M., Caffarella, D. D., Caggiano, C., Cantisani, P. L., Capone, C., Cappelletto, B., Capuano, C., Carangelo, B., Caruselli, G., Chessa, M. A., Chiara, M., Chibbaro, S., Cioffi, V., Ciprianocecchi, P., Colistra, D., Conti, C., Contratti, F., Costella, G. B., Cuoci, A., D'Avella, D., D'Ercole, M., Deangelis, M., Defalco, R., de Luca, G., de Marinis, P., Del Vecchio, C., Delfinis, C., Denaro, L., Deodato, F., Desogus, N., Disomma, A., Domenicucci, M., Dones, F., Fina, M., Fiori, L., Fricia, M., Gaetani, P., Gazzeri, R., Gentile, M., Germano, A., Ghadirpour, R., Gianfreda, C. D., Gigante, N., Gigli, R., Giorgetti, J., Giusa, M., Gravina, U. G., Grippi, L., Guida, F., Guizzardi, G., Iannuzzo, G., Kropp, M., Lattanzi, L., Lucantoni, D., Maffei, L., Magliulo, M., Marconi, F., Marruzzo, D., Martellotta, N., Marton, E., Maugeri, R., Mauro, G., Meli, F., Menniti, A., Merciadri, P., Milanese, L., Nardacci, B., Nasi, D., Orvieto, P., Pacca, P., Pansini, G., Panzarasa, G., Passanisi, M., Pavesi, G., Pizzoni, C., Pulera, F., Rapana, A., Ricci, A., Rispoli, R., Rotondo, M., Russo, N., Santilli, S., Scarano, E., Schwarz, A., Servadei, F., Simonetti, G., Stefini, R., Talamonti, G., Turrisi, A., Valente, V. M., Villa, A., Vindigni, M., Visocchi, M., Vitali, M., Wierzbicki, V., Zambon, G., Zanotti, B., Zenga, F., Alampi, D., Alessandri, F., Aloj, F., Amigoni, A., Aspide, R., Bertuetti, R., Betti, V., Bilotta, F., Bonato, V., Bosco, E., Brita, M., Buscema, G., Cafiero, T., Cappuccio, D., Caradonna, M., Caria, C. G., Casartelliliviero, M., Ciritella, P., Cirrincione, S., Citerio, G., Colelli, S., Coletta, F., Concordia, L., Congedo, E., Covotta, M., Crimella, F., Dall'Acqua, G., De Cassai, A., Defulviis, S., Deperi, E., Deana, C., Delgaudio, A., Denittis, N., Dicolandrea, S., Divezza, F., Ferri, F., Flocco, R., Fontana, C., Forastierimolinari, A., Frangiosa, A., Fumagalli, P., Fuselli, E., Garbarino, M. M., Gelormini, D., Geraci, C., Geraldini, F., Giacomucci, A., Giampaoli, V., Giorgetti, D., Gritti, P., Gualdani, S., Iacovazzo, C., Iermano, C., Latronico, N., Lugari, S., Lusenti, F., Maglione, C., Magnoni, S., Maiarota, F., Malla, M., Marchesi, M., Martino, C., Matteotti, I., Mazzeo, A. T., Morello, G., Nardiello, I., Paticchio, F., Pegoli, M., Perotti, V., Piazzolla, M., Picciafuochi, F., Rachedi, N., Radolovich, D. K., Recchia, A., Riccardi, S., Romagnoli, S., Sala, S., Scafuro, M. A., Sgarlata, P., Soragni, A., Stefani, F., Stival, E., Stofella, G., Terranova, F., Tinturini, R., Togni, T., Toto, R., Trapani, D., Tringali, E., Tullo, L., Valente, A., Valeo, T., Varelli, G., Villani, R., Zamacavicchi, F., Zanello, M., Zarrillo, N., and Zugni, N.

Subjects
medicine.medical_specialty, Decompressive Craniectomy, Consensus development conference, Decompressive craniectomy, Guideline, Traumatic brain injuries, Critical Care, Intracranial Pressure, medicine.medical_treatment, MEDLINE, Neurosurgery, Traumatic brain injurie, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Intensive care, Settore MED/41 - ANESTESIOLOGIA, Brain Injuries, Traumatic, medicine, Humans, Anesthesia, Intensive care medicine, Randomized Controlled Trials as Topic, business.industry, Neurointensive care, Evidence-based medicine, Italy, 030220 oncology & carcinogenesis, Intracranial pressure monitoring, Surgery, Neurology (clinical), Analgesia, Intracranial Hypertension, business, 030217 neurology & neurosurgery, Human
Abstract

No robust evidence is provided by literature regarding the management of intracranial hypertension following severe traumatic brain injury (TBI). This is mostly due to the lack of prospective randomized controlled trials (RCTs), the presence of studies containing extreme heterogeneously collected populations and controversial considerations about chosen outcome. A scientific society should provide guidelines for care management and scientific support for those areas for which evidence-based medicine has not been identified. However, RCTs in severe TBI have failed to establish intervention effectiveness, arising the need to make greater use of tools such as Consensus Conferences between experts, which have the advantage of providing recommendations based on experience, on the analysis of updated literature data and on the direct comparison of different logistic realities. The Italian scientific societies should provide guidelines following the national laws ruling the best medical practice. However, many limitations do not allow the collection of data supporting high levels of evidence for intracranial pressure (ICP) monitoring and decompressive craniectomy (DC) in patients with severe TBI. This intersociety document proposes best practice guidelines for this subsetting of patients to be adopted on a national Italian level, along with joint statements from "TBI Section" of the Italian Society of Neurosurgery (SINch) endorsed by the Neuroanesthesia and Neurocritical Care Study Group of the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI). Presented here is a recap of recommendations on management of ICP and DC supported a high level of available evidence and rate of agreement expressed by the assemblies during the more recent consensus conferences, where members of both groups have had a role of active participants and supporters. The listed recommendations have been sent to a panel of experts consisting of the 107 members of the "TBI Section" of the SINch and the 111 members of the Neuroanesthesia and Neurocritical Care Study Group of the SIAARTI. The aim of the survey was to test a preliminary evaluation of the grade of predictable future adherence of the recommendations following this intersociety proposal. The following recommendations are suggested as representing best clinical practice, nevertheless, adoption of local multidisciplinary protocols regarding thresholds of ICP values, drug therapies, hemostasis management and perioperative care of decompressed patients is strongly recommended to improve treatment efficiency, to increase the quality of data collection and to provide more powerful evidence with future studies. Thus, for this future perspective a rapid overview of the role of the multimodal neuromonitoring in the optimal severe TBI management is also provided in this document. It is reasonable to assume that the recommendations reported in this paper will in future be updated by new observations arising from future trials. They are not binding, and this document should be offered as a guidance for clinical practice through an intersociety agreement, taking in consideration the low level of evidence.

Published
2021

16. Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis

Author

Rowald, A., Komi, S., Demesmaeker, R., Baaklini, E., Hernandez-Charpak, S.D., Paoles, E., Montanaro, H., Cassara, A., Becce, F., Lloyd, B., Newton, T., Ravier, J., Kinany, N., D'Ercole, M., Paley, A., Hankov, N., Varescon, C., McCracken, L., Vat, M., Caban, M., Watrin, A., Jacquet, C., Bole-Feysot, L., Harte, Cathal, Lorach, H., Galvez, A., Tschopp, M., Herrmann, N., Wacker, M., Geernaert, L., Fodor, I., Radevich, V., Keybus, K. Van Den, Eberle, G., Pralong, E., Roulet, M., Ledoux, J.B., Fornari, E., Mandija, S., Mattera, L., Martuzzi, R., Nazarian, B., Benkler, S., Callegari, S., Greiner, N., Fuhrer, B., Froeling, M., Buse, N., Denison, T., Buschman, R., Wende, C., Ganty, D., Bakker, Jurriaan, Delattre, V., Lambert, H., Minassian, K., Berg, C.A.T. van den, Kavounoudias, A., Micera, S., Ville, D. Van De, Barraud, Q., Kurt, E., Kuster, N., Neufeld, E., Capogrosso, M., Asboth, L., Wagner, F.B., Bloch, J., Courtine, G., Rowald, A., Komi, S., Demesmaeker, R., Baaklini, E., Hernandez-Charpak, S.D., Paoles, E., Montanaro, H., Cassara, A., Becce, F., Lloyd, B., Newton, T., Ravier, J., Kinany, N., D'Ercole, M., Paley, A., Hankov, N., Varescon, C., McCracken, L., Vat, M., Caban, M., Watrin, A., Jacquet, C., Bole-Feysot, L., Harte, Cathal, Lorach, H., Galvez, A., Tschopp, M., Herrmann, N., Wacker, M., Geernaert, L., Fodor, I., Radevich, V., Keybus, K. Van Den, Eberle, G., Pralong, E., Roulet, M., Ledoux, J.B., Fornari, E., Mandija, S., Mattera, L., Martuzzi, R., Nazarian, B., Benkler, S., Callegari, S., Greiner, N., Fuhrer, B., Froeling, M., Buse, N., Denison, T., Buschman, R., Wende, C., Ganty, D., Bakker, Jurriaan, Delattre, V., Lambert, H., Minassian, K., Berg, C.A.T. van den, Kavounoudias, A., Micera, S., Ville, D. Van De, Barraud, Q., Kurt, E., Kuster, N., Neufeld, E., Capogrosso, M., Asboth, L., Wagner, F.B., Bloch, J., and Courtine, G.

Abstract

Item does not contain fulltext, Epidural electrical stimulation (EES) targeting the dorsal roots of lumbosacral segments restores walking in people with spinal cord injury (SCI). However, EES is delivered with multielectrode paddle leads that were originally designed to target the dorsal column of the spinal cord. Here, we hypothesized that an arrangement of electrodes targeting the ensemble of dorsal roots involved in leg and trunk movements would result in superior efficacy, restoring more diverse motor activities after the most severe SCI. To test this hypothesis, we established a computational framework that informed the optimal arrangement of electrodes on a new paddle lead and guided its neurosurgical positioning. We also developed software supporting the rapid configuration of activity-specific stimulation programs that reproduced the natural activation of motor neurons underlying each activity. We tested these neurotechnologies in three individuals with complete sensorimotor paralysis as part of an ongoing clinical trial ( www.clinicaltrials.gov identifier NCT02936453). Within a single day, activity-specific stimulation programs enabled these three individuals to stand, walk, cycle, swim and control trunk movements. Neurorehabilitation mediated sufficient improvement to restore these activities in community settings, opening a realistic path to support everyday mobility with EES in people with SCI.

Published
2022

17. CSF neuron-specific enolase as a biomarker of neurovascular conflict severity in drug-resistant trigeminal neuralgia: a prospective study in patients submitted to microvascular decompression

Author

Baroni, Silvia, Rapisarda, A., Gentili, Vanessa, Burattini, Benedetta, Moretti, G., Sarlo, F., Izzo, A., D'Ercole, Manuela, Olivi, Alessandro, Urbani, A., Montano, Nicola, Gentili V., Burattini B., D'Ercole M., Olivi A. (ORCID:0000-0002-4489-7564), Montano N. (ORCID:0000-0002-4965-1950), Baroni, Silvia, Rapisarda, A., Gentili, Vanessa, Burattini, Benedetta, Moretti, G., Sarlo, F., Izzo, A., D'Ercole, Manuela, Olivi, Alessandro, Urbani, A., Montano, Nicola, Gentili V., Burattini B., D'Ercole M., Olivi A. (ORCID:0000-0002-4489-7564), and Montano N. (ORCID:0000-0002-4965-1950)

Abstract

Background: Although neurovascular conflict (NVC) is the most widely accepted cause of trigeminal neuralgia (TN), few articles have analyzed molecular and biochemical mechanisms underlying TN. In the present study, we dosed neuron-specific enolase (NSE) on serum and CSF samples of 20 patients submitted to microvascular decompression (MVD) and correlated these findings with the type of NVC. Methods: Blood samples were obtained preoperatively and 48 h after MVD. CSF from trigeminal cistern was intraoperatively obtained. NSE levels were measured using the Diasorin kit (LIAISON®NSE). NVC was classified as “contact” or “trigeminal nerve distortion/indentation” or “trigeminal root atrophy” based on MRI and intraoperative findings. Clinical outcome was measured by acute pain relief (APR) and Barrow Neurological Institute (BNI) scale at last available follow-up (FU; 6.40 ± 5.38 months). Results: APR was obtained in all patients. A statistically significant BNI reduction was obtained at latest FU (p < 0.0001). Serum NSE levels significantly decreased following MVD (from 12.15 ± 3.02 ng/mL to 8.95 ± 2.83 ng/mL, p = 0.001). The mean CSF NSE value was 48.94 ng/mL, and the mean CSF/serum NSE rate was 4.18 with a strong correlation between these two variables (p = 0.0008). CSF NSE level in “trigeminal root atrophy” group was significantly higher compared to “contact” (p = 0.0045) and “distortion/indentation” (p = 0.010) groups. Conclusion: NSE levels seem to be related to the etiopathology and severity of NVC. A significant reduction of serum NSE levels could be related to the resolution of the NVC and clinical TN improvement.

Published
2022

18. Surgical and Clinical Outcomes of Microvascular Decompression: A Comparative Study between Young and Elderly Patients

Author

Menna, Grazia, Rapisarda, A., Izzo, A., D'Ercole, Manuela, D'Alessandris, Quintino Giorgio, Olivi, Alessandro, Montano, Nicola, Menna G., D'Ercole M., D'Alessandris Q. G. (ORCID:0000-0002-2953-9291), Olivi A. (ORCID:0000-0002-4489-7564), Montano N. (ORCID:0000-0002-4965-1950), Menna, Grazia, Rapisarda, A., Izzo, A., D'Ercole, Manuela, D'Alessandris, Quintino Giorgio, Olivi, Alessandro, Montano, Nicola, Menna G., D'Ercole M., D'Alessandris Q. G. (ORCID:0000-0002-2953-9291), Olivi A. (ORCID:0000-0002-4489-7564), and Montano N. (ORCID:0000-0002-4965-1950)

Abstract

Microvascular decompression (MVD) is the only etiological technique for the treatment of trigeminal neuralgia (TN). Whilst there is a consensus MVD is likely effective regardless of age, the elderly population is thought to be more prone to have a higher rate of surgical complication, morbidity, and mortality. The main objective of our single-center, retrospective study was to analyze the surgical and clinical outcomes of MVD in TN elderly patients. From a surgical series of patients with TN who had undergone MVD from April 2018 to April 2022, 76 patients who matched the inclusion criteria were divided into two groups: twenty-five (32.9%) patients were older than 65 years and included in the elderly group, while the remaining fifty-one (61.1%) patients were below 65 years included in the non-elderly one. There were no differences between the groups in terms of acute pain relief (APR), Barrow Neurological Index (BNI) at follow-up, complications, and recurrence rate. In multivariate analysis (Cox proportional hazards regression analysis) the presence of an offending artery with nerve root distortion/indentation emerged as the only independent prognostic factor for pain-free survival (p = 0.0001). Our data endorse MVD as a safe and effective surgical procedure also for elderly patients with TN.

Published
2022

19. Factors Related to Hemifacial Spasm Recurrence in Patients Undergoing Microvascular Decompression—A Systematic Review and Meta-Analysis

Author

Menna, Grazia, Battistelli, Marco, Rapisarda, Alessandro, Izzo, A., D'Ercole, Manuela, Olivi, Alessandro, Montano, Nicola, Menna G., Battistelli M., Rapisarda A., D'ercole M., Olivi A. (ORCID:0000-0002-4489-7564), Montano N. (ORCID:0000-0002-4965-1950), Menna, Grazia, Battistelli, Marco, Rapisarda, Alessandro, Izzo, A., D'Ercole, Manuela, Olivi, Alessandro, Montano, Nicola, Menna G., Battistelli M., Rapisarda A., D'ercole M., Olivi A. (ORCID:0000-0002-4489-7564), and Montano N. (ORCID:0000-0002-4965-1950)

Abstract

There is a lack of knowledge about the factors associated with the recurrence of hemifacial spam (HFS) following an initially successful microvascular decompression (MVD) surgery. The aim of the present study was to systematically review the pertinent literature and carry out a meta-analysis of factors linked to HFS recurrence in patients undergoing initially successful MVD treatment. An online literature search was launched on the PubMed/Medline and Scopus databases. The following data were collected: sex, age at surgery, affected side, reported improvement after surgery, presence of post-operatory facial weakness, symptom duration, offender vessels, and data obtained from intraoperative neurophysiological monitoring. Upon full-text review, eight articles were included, studying 1105 patients, of which 64 (5.7%) reported recurrence after MVD surgery for hemifacial spasm. There was a statistically significant increased incidence of HFS recurrence in patients with the persistence of lateral spread response (LSR after surgery (OR 9.44 (95% CI 1.69– 52.58) p 0.01), while those patients experiencing a shorter disease duration before going to surgery were significantly less prone to experiencing disease recurrence (OR 0.11 (95% CI 0.03–0.46) p 0.002). The remaining examined factors did not result as significantly associated with the risk of recurrence. The funnel plots were largely symmetrical for each variable studied. Taken together, the results of our meta-analysis seem to suggest that short-term symptom duration is a protective factor against HFS recurrence after MVD surgery, while LSR persistence is a negative prognostic factor. Well-designed randomized controlled clinical trials with a long follow-up are expected to further explore therapeutic alternatives for HFS recurrence.

Published
2022

20. ADP Formation In Rat Liver

Author

Vannoni, D., Leoncini, R., DiPietro, M. C., D’Ercole, M., Tabucchi, A., Rosi, F., Marinello, E., Griesmacher, Andrea, editor, Müller, Mathias M., editor, and Chiba, Peter, editor

Published
1998
Full Text
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21. Gender Equality since 1900

Author

Dilli, Selin, Carmichael, Sarah, Rijpma, Auke, van Zanden, Jan Luiten, Malinowski, M., d'Ercole, M., LS Gender-werk in verg.hist.perspectief, and OGKG - Sociaal-economische geschiedenis

Abstract

This chapter provides an overview of global trends in gender equality in health, socio-economic resources and politics over the entire 20th century. It does so by extending the historical gender equality index (HGEI) introduced in the previous How Was Life? report back to 1900 and forward to 2010, and by including additional indicators. While progress since 1900 towards gender equality is visible especially in the dimensions of health and socio-economic resources, cluster analysis reveals that the groupings of countries by level of gender equality remains similar through time. The main exceptions are Southern Europe and the Nordic countries, which witness substantial improvements in the post-1950 period. https://www.oecd-ilibrary.org/social-issues-migration-health/how-was-life-volume-ii_d005dfaf-en

Published
2021

23. Gender Equality since 1900

Author

LS Gender-werk in verg.hist.perspectief, OGKG - Sociaal-economische geschiedenis, Dilli, Selin, Carmichael, Sarah, Rijpma, Auke, van Zanden, Jan Luiten, Malinowski, M., d'Ercole, M., LS Gender-werk in verg.hist.perspectief, OGKG - Sociaal-economische geschiedenis, Dilli, Selin, Carmichael, Sarah, Rijpma, Auke, van Zanden, Jan Luiten, Malinowski, M., and d'Ercole, M.

Published
2021

24. CREATIVE ARTS INTERVENTIONS IN ADDRESSING DEPRESSION IN OLDER ADULTS: A SYSTEMATIC REVIEW

Author

Sajnani, N, Dunphy, K, Baker, F, Dumaresq, E, Caroll-Haskins, K, Eickholt, J, Ercole, M, Kaimal, G, Sajnani, N, Dunphy, K, Baker, F, Dumaresq, E, Caroll-Haskins, K, Eickholt, J, Ercole, M, and Kaimal, G

Abstract

Depression experienced by older adults is proving an increasing global health burden, with rates as high as 27% in the USA. This is likely to increase in coming years as the number and proportion of older adults in the global population rises. Therefore, it is imperative that the effectiveness of approaches to the prevention and treatment of depression are understood. Creative arts interventions, including art, dance movement, drama, and music, are utilized internationally to reduce depressive symptoms in older adults and promote wellbeing. This includes interventions led by trained arts therapists as well as other health and arts professionals. This presentation will include a report of findings from a recent systematic review of the outcomes of four creative arts modalities (art, dance movement, drama, and music) with particular attention paid to processes of change documented in each modality.

Published
2021

25. Is There a Place for Spinal Cord Stimulation in the Management of Patients with Multiple Sclerosis? A Systematic Review of the Literature

Author

Rapisarda, Alessandro, Ioannoni, E., Izzo, A., D'Ercole, Manuela, Montano, Nicola, Rapisarda A., D'Ercole M., Montano N. (ORCID:0000-0002-4965-1950), Rapisarda, Alessandro, Ioannoni, E., Izzo, A., D'Ercole, Manuela, Montano, Nicola, Rapisarda A., D'Ercole M., and Montano N. (ORCID:0000-0002-4965-1950)

Abstract

Objective. Spinal cord stimulation (SCS) is a minimally invasive technique mainly used to treat neuropathic pain associated with failed back surgery syndrome. However, this therapy has been utilized to treat other chronic painful conditions, such as pain associated with multiple sclerosis (MS). Nonetheless, the efficacy of SCS in MS patients has not been fully established. In fact, in most of SCS series, MS patients represent only a subset of a bigger cohort which comprises different causes of pain, motor disorder, and other functional limitations. The aim of our study was to systematically review the literature to evaluate the effectiveness of SCS in MS patients. Methods. A literature search was performed through different databases (PubMed, Scopus, and Embase) using the following terms: "multiple sclerosis,""spinal cord stimulation,"and "dorsal column stimulation,"according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines. Results. A total of 452 articles were reviewed, and 7 studies were included in the present analysis. 373 MS patients were submitted to a stimulation trial, and 82 MS patients underwent a de novo implantation. 285/373 (76.4%) of cases submitted to the SCS trial were enrolled for permanent stimulation. We found a long-lasting improvement in 193/346 (55.8%) MS patients with motor disorders, in 90/134 (67.13%) MS patients with urinary dysfunction, and in 28/34 (82.35%) MS patients with neuropathic pain. The efficacy of SCS was higher for urinary dysfunction (p = 0.0144) and neuropathic pain (p = 0.0030) compared with motor disorders. Conclusions. Our systematic review evidences that SCS is effective in MS patients. Urinary dysfunction and pain symptoms seem to be most responsive to SCS. Further studies are needed to improve the patient selection and clarify the best timing to perform SCS in these patients.

Published
2021

26. Management of intracranial hypertension following traumatic brain injury: A best clinical practice adoption proposal for intracranial pressure monitoring and decompressive craniectomy: Joint statements by the Traumatic Brain Injury Section of the Italian Society of Neurosurgery (SINch) and the Neuroanesthesia and Neurocritical Care Study Group of the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI)

Author

Iaccarino, C., Lippa, L., Munari, M., Castioni, C. A., Robba, C., Caricato, Anselmo, Pompucci, Angelo, Signoretti, S., Zona, G., Rasulo, F. A., Aimar, E., Amato, S., Angileri, F. F., Anile, Carmelo, Assietti, R., Baratto, V., Barbanera, A., Basile, L., Battaglia, R., Bellocchi, S., Bertuccio, A., Blanco, S., Bolognini, A., Boniferro, B., Bordi, L., Bortolotti, C., Brandini, V., Broger, Maximilian, Brollo, M., Caffarella, D. D., Caggiano, Cinzia, Cantisani, P. L., Capone, C., Cappelletto, B., Capuano, C., Carangelo, B., Caruselli, G., Chessa, M. A., Chiara, M., Chibbaro, S., Cioffi, V., Ciprianocecchi, P., Colistra, D., Conti, C., Contratti, F., Costella, G. B., Cuoci, A., D'Avella, D., D'Ercole, Manuela, Deangelis, M., Defalco, R., de Luca, G., de Marinis, P., Del Vecchio, C., Delfinis, C., Denaro, Luca, Deodato, F., Desogus, N., Disomma, A., Domenicucci, M., Dones, F., Fina, M., Fiori, L., Fricia, M., Gaetani, P., Gazzeri, R., Gentile, M., Germano, A., Ghadirpour, R., Gianfreda, C. D., Gigante, N., Gigli, R., Giorgetti, J., Giusa, M., Gravina, U. G., Grippi, L., Guida, F., Guizzardi, G., Iannuzzo, G., Kropp, M., Lattanzi, L., Lucantoni, D., Maffei, L., Magliulo, M., Marconi, F., Marruzzo, D., Martellotta, N., Marton, E., Maugeri, R., Mauro, G., Meli, F., Menniti, A., Merciadri, P., Milanese, L., Nardacci, B., Nasi, D., Orvieto, P., Pacca, P., Pansini, G., Panzarasa, G., Passanisi, M., Pavesi, G., Pizzoni, C., Pulera, F., Rapana, A., Ricci, A., Rispoli, R., Rotondo, M., Russo, N., Santilli, S., Scarano, E., Schwarz, A., Servadei, Franco, Simonetti, G., Stefini, R., Talamonti, G., Turrisi, A., Valente, V. M., Villa, A., Vindigni, M., Visocchi, Massimiliano, Vitali, M., Wierzbicki, V., Zambon, G., Zanotti, B., Zenga, F., Alampi, D., Alessandri, F., Aloj, F., Amigoni, A., Aspide, R., Bertuetti, R., Betti, V., Bilotta, F., Bonato, V., Bosco, E., Brita, M., Buscema, G., Cafiero, T., Cappuccio, D., Caradonna, M., Caria, C. G., Casartelliliviero, M., Ciritella, P., Cirrincione, S., Citerio, G., Colelli, S., Coletta, F., Concordia, L., Congedo, E., Covotta, M., Crimella, F., Dall'Acqua, G., De Cassai, A., Defulviis, S., Deperi, E., Deana, C., Delgaudio, A., Denittis, N., Dicolandrea, S., Divezza, F., Ferri, F., Flocco, R., Fontana, C., Forastierimolinari, A., Frangiosa, A., Fumagalli, P., Fuselli, E., Garbarino, M. M., Gelormini, D., Geraci, C., Geraldini, F., Giacomucci, A., Giampaoli, V., Giorgetti, D., Gritti, P., Gualdani, S., Iacovazzo, C., Iermano, C., Latronico, N., Lugari, S., Lusenti, F., Maglione, C., Magnoni, S., Maiarota, F., Malla, M., Marchesi, M., Martino, C., Matteotti, I., Mazzeo, A. T., Morello, G., Nardiello, I., Paticchio, F., Pegoli, M., Perotti, Valerio, Piazzolla, M., Picciafuochi, F., Rachedi, N., Radolovich, D. K., Recchia, A., Riccardi, S., Romagnoli, S., Sala, S., Scafuro, M. A., Sgarlata, P., Soragni, A., Stefani, F., Stival, Eleonora, Stofella, G., Terranova, F., Tinturini, R., Togni, T., Toto, R., Trapani, D., Tringali, E., Tullo, L., Valente, A., Valeo, T., Varelli, G., Villani, R., Zamacavicchi, F., Zanello, M., Zarrillo, N., Zugni, N., Caricato A. (ORCID:0000-0001-5929-120X), Pompucci A. (ORCID:0000-0002-5427-9719), Anile C. (ORCID:0000-0002-0481-9713), Broger M., Caggiano C., D'Ercole M., Denaro L., Servadei F., Visocchi M. (ORCID:0000-0003-1087-0491), Perotti V. (ORCID:0000-0001-9461-2101), Stival E., Iaccarino, C., Lippa, L., Munari, M., Castioni, C. A., Robba, C., Caricato, Anselmo, Pompucci, Angelo, Signoretti, S., Zona, G., Rasulo, F. A., Aimar, E., Amato, S., Angileri, F. F., Anile, Carmelo, Assietti, R., Baratto, V., Barbanera, A., Basile, L., Battaglia, R., Bellocchi, S., Bertuccio, A., Blanco, S., Bolognini, A., Boniferro, B., Bordi, L., Bortolotti, C., Brandini, V., Broger, Maximilian, Brollo, M., Caffarella, D. D., Caggiano, Cinzia, Cantisani, P. L., Capone, C., Cappelletto, B., Capuano, C., Carangelo, B., Caruselli, G., Chessa, M. A., Chiara, M., Chibbaro, S., Cioffi, V., Ciprianocecchi, P., Colistra, D., Conti, C., Contratti, F., Costella, G. B., Cuoci, A., D'Avella, D., D'Ercole, Manuela, Deangelis, M., Defalco, R., de Luca, G., de Marinis, P., Del Vecchio, C., Delfinis, C., Denaro, Luca, Deodato, F., Desogus, N., Disomma, A., Domenicucci, M., Dones, F., Fina, M., Fiori, L., Fricia, M., Gaetani, P., Gazzeri, R., Gentile, M., Germano, A., Ghadirpour, R., Gianfreda, C. D., Gigante, N., Gigli, R., Giorgetti, J., Giusa, M., Gravina, U. G., Grippi, L., Guida, F., Guizzardi, G., Iannuzzo, G., Kropp, M., Lattanzi, L., Lucantoni, D., Maffei, L., Magliulo, M., Marconi, F., Marruzzo, D., Martellotta, N., Marton, E., Maugeri, R., Mauro, G., Meli, F., Menniti, A., Merciadri, P., Milanese, L., Nardacci, B., Nasi, D., Orvieto, P., Pacca, P., Pansini, G., Panzarasa, G., Passanisi, M., Pavesi, G., Pizzoni, C., Pulera, F., Rapana, A., Ricci, A., Rispoli, R., Rotondo, M., Russo, N., Santilli, S., Scarano, E., Schwarz, A., Servadei, Franco, Simonetti, G., Stefini, R., Talamonti, G., Turrisi, A., Valente, V. M., Villa, A., Vindigni, M., Visocchi, Massimiliano, Vitali, M., Wierzbicki, V., Zambon, G., Zanotti, B., Zenga, F., Alampi, D., Alessandri, F., Aloj, F., Amigoni, A., Aspide, R., Bertuetti, R., Betti, V., Bilotta, F., Bonato, V., Bosco, E., Brita, M., Buscema, G., Cafiero, T., Cappuccio, D., Caradonna, M., Caria, C. G., Casartelliliviero, M., Ciritella, P., Cirrincione, S., Citerio, G., Colelli, S., Coletta, F., Concordia, L., Congedo, E., Covotta, M., Crimella, F., Dall'Acqua, G., De Cassai, A., Defulviis, S., Deperi, E., Deana, C., Delgaudio, A., Denittis, N., Dicolandrea, S., Divezza, F., Ferri, F., Flocco, R., Fontana, C., Forastierimolinari, A., Frangiosa, A., Fumagalli, P., Fuselli, E., Garbarino, M. M., Gelormini, D., Geraci, C., Geraldini, F., Giacomucci, A., Giampaoli, V., Giorgetti, D., Gritti, P., Gualdani, S., Iacovazzo, C., Iermano, C., Latronico, N., Lugari, S., Lusenti, F., Maglione, C., Magnoni, S., Maiarota, F., Malla, M., Marchesi, M., Martino, C., Matteotti, I., Mazzeo, A. T., Morello, G., Nardiello, I., Paticchio, F., Pegoli, M., Perotti, Valerio, Piazzolla, M., Picciafuochi, F., Rachedi, N., Radolovich, D. K., Recchia, A., Riccardi, S., Romagnoli, S., Sala, S., Scafuro, M. A., Sgarlata, P., Soragni, A., Stefani, F., Stival, Eleonora, Stofella, G., Terranova, F., Tinturini, R., Togni, T., Toto, R., Trapani, D., Tringali, E., Tullo, L., Valente, A., Valeo, T., Varelli, G., Villani, R., Zamacavicchi, F., Zanello, M., Zarrillo, N., Zugni, N., Caricato A. (ORCID:0000-0001-5929-120X), Pompucci A. (ORCID:0000-0002-5427-9719), Anile C. (ORCID:0000-0002-0481-9713), Broger M., Caggiano C., D'Ercole M., Denaro L., Servadei F., Visocchi M. (ORCID:0000-0003-1087-0491), Perotti V. (ORCID:0000-0001-9461-2101), and Stival E.

Abstract

No robust evidence is provided by literature regarding the management of intracranial hypertension following severe traumatic brain injury (TBI). This is mostly due to the lack of prospective randomized controlled trials (RCTs), the presence of studies containing extreme heterogeneously collected populations and controversial considerations about chosen outcome. A scientific society should provide guidelines for care management and scientific support for those areas for which evidence-based medicine has not been identified. However, RCTs in severe TBI have failed to establish intervention effectiveness, arising the need to make greater use of tools such as Consensus Conferences between experts, which have the advantage of providing recommendations based on experience, on the analysis of updated literature data and on the direct comparison of different logistic realities. The Italian scientific societies should provide guidelines following the national laws ruling the best medical practice. However, many limitations do not allow the collection of data supporting high levels of evidence for intracranial pressure (ICP) monitoring and decompressive craniectomy (DC) in patients with severe TBI. This intersociety document proposes best practice guidelines for this subsetting of patients to be adopted on a national Italian level, along with joint statements from “TBI Section” of the Italian Society of Neurosurgery (SINch) endorsed by the Neuroanesthesia and Neurocritical Care Study Group of the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI). Presented here is a recap of recommendations on management of ICP and DC supported a high level of available evidence and rate of agreement expressed by the assemblies during the more recent consensus conferences, where members of both groups have had a role of active participants and supporters. The listed recommendations have been sent to a panel of experts consisting of the 107 members of the “T

Published
2021

27. Factors associated with cerebrospinal fluid leak after a retrosigmoid approach for cerebellopontine angle surgery

Author

Montano, Nicola, Signorelli, Francesco, Giordano, Marco, D'Onofrio, F. G., Izzo, A., D'Ercole, Manuela, Ioannoni, E., Pennisi, Giovanni, Caricato, Anselmo, Pallini, Roberto, Olivi, Alessandro, Montano N. (ORCID:0000-0002-4965-1950), Signorelli F. (ORCID:0000-0001-8431-0433), Giordano M., D'Ercole M., Pennisi G., Caricato A. (ORCID:0000-0001-5929-120X), Pallini R. (ORCID:0000-0002-4611-8827), Olivi A. (ORCID:0000-0002-4489-7564), Montano, Nicola, Signorelli, Francesco, Giordano, Marco, D'Onofrio, F. G., Izzo, A., D'Ercole, Manuela, Ioannoni, E., Pennisi, Giovanni, Caricato, Anselmo, Pallini, Roberto, Olivi, Alessandro, Montano N. (ORCID:0000-0002-4965-1950), Signorelli F. (ORCID:0000-0001-8431-0433), Giordano M., D'Ercole M., Pennisi G., Caricato A. (ORCID:0000-0001-5929-120X), Pallini R. (ORCID:0000-0002-4611-8827), and Olivi A. (ORCID:0000-0002-4489-7564)

Abstract

Background: The retrosigmoid approach represents a crucial surgical route to address different lesions in the cerebellopontine angle but cerebrospinal fluid (CSF) leak still remains the most frequent complication after this approach. Here, we analyzed the impact of different factors in CSF leak development after a retrosigmoid approach. Identifying risk factors related to a specific approach may help the surgeon to tailor the perioperative management and to appropriately counsel patients regarding their risk profile. Methods: We retrospectively reviewed the clinical, surgical, and outcome data of 103 consecutive patients (M/F, 47/56; mean follow-up 35.6 ± 23.9 months) who underwent a retrosigmoid approach for different cerebellopontine angle pathologies and studied the impact of different factors on the occurrence of a CSF leak to univariate and multivariate analysis. Results: Seventy-nine patients (76.7%) were operated for tumors growing in the cerebellopontine angle. Twenty-four patients (23.2%) underwent microvascular decompression to treat a drug-resistant trigeminal neuralgia. Sixteen patients (15.5%) developed CSF leak in the postoperative course of which six underwent surgical revision. Performing a craniectomy as surgical procedure (P = 0.0450) and performing a reopening procedure (second surgery; P = 0.0079) were significantly associated to a higher risk of developing CSF leak. Moreover, performing a reopening procedure emerged as an independent factor for CSF developing on multivariate analysis (P = 0.0156). Conclusion: Patients submitted to craniectomy and patients who underwent a second surgery showed an higher CSF leak rate. Ongoing improvement of biomaterial technology may help neurosurgeons to prevent this potentially life-threatening complication.

Published
2021

28. The Impact of Neuronavigation on the Surgical Outcome of Microvascular Decompression for Trigeminal Neuralgia

Author

Legninda Sop, F. Y., D'Ercole, Manuela, Izzo, A., Rapisarda, Alessandro, Ioannoni, E., Caricato, Anselmo, Olivi, Alessandro, Montano, Nicola, D'Ercole M., Rapisarda A., Caricato A. (ORCID:0000-0001-5929-120X), Olivi A. (ORCID:0000-0002-4489-7564), Montano N. (ORCID:0000-0002-4965-1950), Legninda Sop, F. Y., D'Ercole, Manuela, Izzo, A., Rapisarda, Alessandro, Ioannoni, E., Caricato, Anselmo, Olivi, Alessandro, Montano, Nicola, D'Ercole M., Rapisarda A., Caricato A. (ORCID:0000-0001-5929-120X), Olivi A. (ORCID:0000-0002-4489-7564), and Montano N. (ORCID:0000-0002-4965-1950)

Abstract

Objective: Microvascular decompression (MVD) is considered the only etiological treatment for drug-resistant trigeminal neuralgia (TN). Nonetheless, despite the recent technological advances, the risks associated with MVD remain non-negligible. The aim of this study was to evaluate the impact of using neuronavigation on the surgical outcomes of patients with TN submitted for MVD. Methods: We analyzed 30 consecutive patients (11 men, 19 women) who underwent MVD for TN between January 2019 and December 2019. Patients were divided in 2 groups according to the use of neuronavigation (group A: MVD with neuronavigation; group B: MVD without neuronavigation). The impact of neuronavigation was assessed on the following parameters: craniotomy size, surgical duration, mastoid air cell opening, postoperative cerebrospinal fluid (CSF) leakage and other complications occurrence, and length of hospitalization. The acute pain relief and the Barrow Neurological Institute score at follow-up were used to evaluate the functional outcome. Results: The craniotomy size, the surgical duration, and the CSF leak incidence were significantly reduced in group A compared with group B (P = 0.0009, P = 0.0369, and P = 0.0406, respectively). The incidence of mastoid air cell opening, and the length of hospitalization were reduced in group A compared with group B, although these differences were not statistically significant. We obtained an acute pain relief in all cases, and the Barrow Neurological Institute score at follow-up was significantly reduced (P < 0.0001). Conclusions: Neuronavigation is a useful tool that significantly reduced craniotomy size, surgical duration, and CSF leak incidence in patients with TN submitted for MVD. We advise to routinely implement neuronavigation in this type of surgery.

Published
2021

29. Interaction of wheelspace coolant and main flow in a new aeroderivative low pressure turbine

Author

Montomoli, F., Massini, M., Maceli, N., Cirri, M., Lombardi, L., Ciani, A., D'Ercole, M., and De Prosperis, R.

Subjects
Turbines -- Properties, Turbomachines -- Research, Science and technology
Abstract

Increased computational capabilities make available for the aero/thermal designers new powerful tools to include more geometrical details, improving the accuracy of the simulations and reducing design costs and time. In the present work, a low-pressure turbine was analyzed, modeling the rotor-stator including the wheel space region. Attention was focused on the interaction between the coolant and the main flow in order to obtain a more detailed understanding of the behavior of the angel wings, to evaluate the wall heat flux distribution, and to prevent hot gas ingestion. Issues of component reliability related to thermal stress require accurate modeling of the turbulence and unsteadiness of the flow field. To satisfy, this accuracy requirement, a full 3D URANS simulation was carried out. A reduced count ratio technique was applied in order to decrease numerical simulation costs. The study was carried out to investigate a new two-stage low-pressure turbine from GE Infrastructure Oil & Gas to be coupled to a new aeroderivative gas generator (the LM2500 + G4) developed by GE Infrastructure, Aviation. [DOI: 10.1115/1.3195036]

Published
2010

34. Creative Arts Interventions to Address Depression in Older Adults: A Systematic Review of Outcomes, Processes, and Mechanisms

Author

Dunphy, K, Baker, FA, Dumaresq, E, Carroll-Haskins, K, Eickholt, J, Ercole, M, Kaimal, G, Meyer, K, Sajnani, N, Shamir, OY, Wosch, T, Dunphy, K, Baker, FA, Dumaresq, E, Carroll-Haskins, K, Eickholt, J, Ercole, M, Kaimal, G, Meyer, K, Sajnani, N, Shamir, OY, and Wosch, T

Abstract

Depression experienced by older adults is proving an increasing global health burden, with rates generally 7% and as high as 27% in the USA. This is likely to significantly increase in coming years as the number and proportion of older adults in the population rises all around the world. Therefore, it is imperative that the effectiveness of approaches to the prevention and treatment of depression are understood. Creative arts interventions, including art, dance movement, drama, and music modalities, are utilized internationally to target depression and depressive symptoms in older adults. This includes interventions led by trained arts therapists as well as other health and arts professionals. However, to date there has not been a systematic review that reports effects and examines the processes (why) and mechanisms (how) of creative arts interventions are used to address depression in this older age group. This systematic review of studies on creative arts interventions for older adults experiencing depression examined: outcomes of four creative arts modalities (art, dance movement, drama, and music); with particular attention paid to processes documented as contributing to change in each modality; and mechanisms considered to result from these processes. Our analysis of 75 articles (17 art, 13 dance, 4 drama, and 41 music) indicates mostly significant quantitative or positive qualitative findings, particularly for interventions led by creative arts therapists. Mechanisms of change gleaned from the studies that were common across modalities include physical (e.g., increased muscle strength; neurochemical effects, such as endorphin release), intra-personal (e.g., enhanced self-concept, strengthened agency and mastery; processing and communication of emotions), cultural (e.g., creative expression, aesthetic pleasure), cognitive (e.g., stimulation of memory), and social (e.g., increased social skills and connection), that were all considered to contribute to reduced d

Published
2019

36. Valutazione dei risultati produttivi delle prove nazionali 2016-2017. Orzo: buoni risultati produttivi nonostante i mesi siccitosi

Author

Cattivelli L., Faccini N., Gianinetti A., Alberici R., Amato G., Anastasi U., Attene G., Baravelli M., Barbiani G., Baronchelli M., Belocchi A., Bonciarelli U., Cacciatori P., Civitella D., Codianni P., D’Ercole M., De Francesco L., Delbono S., Donadeo, G., Faeti V., Fecondo G., Fina C., Fornara M., Frenda A. S., Fuselli D., Ghizzoni R., Giambalvo D., Invernizzi C., Licciardello S., Lorenzetti M., Marino A., Mastrorilli M., Mazzieri G., Mazzon V., Monti M., Moscaritolo S., Notario T., Pagani D., Pala T., Palumbo M., Petrini A., Pilati A., Poma I., Pons R., Preiti G., Quaranta F., Randazzo B., Reggiani F., Rizzo G., Rodriguez M., Romeo M., Ruisi P., Sarno M., Scarcella M., Sciacca F., Signor M., Tagliaferri I., Venezia G., Viola P., Virdis A., Virgillito S., Virzì N., Cattivelli, L., Faccini, N., Gianinetti, A., Alberici, R., Amato, G., Anastasi, U., Attene, G., Baravelli, M., Barbiani, G., Baronchelli, M., Belocchi, A., Bonciarelli, U., Cacciatori, P., Civitella, D., Codianni, P., D’Ercole, M., De Francesco, L., Delbono, S., Donadeo, G., Faeti, V., Fecondo, G., Fina, C., Fornara, M., Frenda, A., Fuselli, D., Ghizzoni, R., Giambalvo, D., Invernizzi, C., Licciardello, S., Lorenzetti, M., Marino, A., Mastrorilli, M., Mazzieri, G., Mazzon, V., Monti, M., Moscaritolo, S., Notario, T., Pagani, D., Pala, T., Palumbo, M., Petrini, A., Pilati, A., Poma, I., Pons, R., Preiti, G., Quaranta, F., Randazzo, B., Reggiani, F., Rizzo, G., M., R., Romeo, M., Ruisi, P., Sarno, M., Scarcella, M., Sciacca, F., Signor, M., Tagliaferri, I., Venezia, G., Viola, P., Virdis, A., Virgillito, S., and Virzì, N.

Subjects
confronto varietale, Orzo zootecnico, Adattabilità ambientale, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Abstract

Le precipitazioni praticamente assenti dal mese di febbraio non hanno compromesso le produzioni dell’orzo, che hanno raggiunto 7,1 t/ha al Nord, 6,8 al Centro e 6,4 t/ha al Sud e nelle Isole. La Rete delle prove ha riguardato la valutazione di 36 varietà di orzo da zootecnia in diverse località rappresentative della produzione nazionale.

Published
2017

37. Risultati produttivi e qualitativi delle prove varietali 2016-2017: Annata positiva per l’orzo da birra al Centro-Sud

Author

Cattivelli L., Faccini N., Gianinetti A., Alberici R., Amato G., Anastasi U., Attene G., Baravelli M., Barbiani G., Baronchelli M., Belocchi A., Bonciarelli U., Cacciatori P., Civitella D., Codianni P., D’ercole M., De Francesco L., Delbono S., Donadeo G., Faeti V., Fecondo G., Fina C., Fornara M., Frenda A. S., Fuselli D., Ghizzoni R., Giambalvo D., Invernizzi C., Licciardello S., Lorenzetti M. C., Marino A., Mastrorilli M., Mazzieri G., Mazzon V., Monti M., Moscaritolo S., Notario T., Pagani D., Pala T., Palumbo M., Petrini A., Pilati A., Poma I., Pons R., Preiti G., Quaranta F., Randazzo B., Reggiani F., Rizzo G., Rodriguez M., Romeo M., Ruisi P., Sarno M., Scarcella M., Sciacca F., Signor M., Tagliaferri I., Venezia G., Viola P., Virdis A., Virgillito S., Virzì N., Cattivelli, L., Faccini, N., Gianinetti, A., Alberici, R., Amato, G., Anastasi, U., Attene, G., Baravelli, M., Barbiani, G., Baronchelli, M., Belocchi, A., Bonciarelli, U., Cacciatori, P., Civitella, D., Codianni, P., D’Ercole, M., De Francesco, L., Delbono, S., Donadeo, G., Faeti, V., Fecondo, G., Fina, C., Fornara, M., Frenda, A., Fuselli, D., Ghizzoni, R., Giambalvo, D., Invernizzi, C., Licciardello, S., Lorenzetti, M., Marino, A., Mastrorilli, M., Mazzieri, G., Mazzon, V., Monti, M., Moscaritolo, S., Notario, T., Pagani, D., Pala, T., Palumbo, M., Petrini, A., Pilati, A., Poma, I., Pons, R., Preiti, G., Quaranta, F., Randazzo, B., Reggiani, F., Rizzo, G., M., R., Romeo, M., Ruisi, P., Sarno, M., Scarcella, M., Sciacca, F., Signor, M., Tagliaferri, I., Venezia, G., Viola, P., Virdis, A., Virgillito, S., and Virzì, N.

Subjects
confronto varietale, Orzo da malto, Adattabilità ambientale, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Abstract

Riscuotono maggiore interesse i risultati delle prove effettuate al Centro-Sud, dato che la coltivazione dell’orzo da birra si concentra lì: la media produttiva è stata di 5,7 t/ha. Al Nord le prove sono utili per un futuro sviluppo della coltura: in questo caso la produzione media è stata di 4,9 t/ha

Published
2017

38. Le varietà di triticale consigliate per le semine 2017-2018

Author

Faccini N., Cattivelli L., Alberici R., Baronchelli M., Barbiani G., Cacciatori V., Codianni P., D’Ercole M., Delbono S., Di Miceli G., Faeti V., Fecondo G., Fornara M., Frenda A. S., Fuselli D., Ghizzoni R., Giunta F., Lottari M., Marino A., Moscaritolo S., Notario T., Pagani D., Petrini G., Poma I., Quaranta F., Randazzo B., Ruisi P., Signor M., Viola P., Virdis A., Tagliaferri I., Faccini, N., Cattivelli, L., Alberici, R., Baronchelli, M., Barbiani, G., Cacciatori, V., Codianni, P., D’Ercole, M., Delbono, S., Di Miceli, G., Faeti, V., Fecondo, G., Fornara, M., Frenda, A., Fuselli, D., Ghizzoni, R., Giunta, F., Lottari, M., Marino, A., Moscaritolo, S., Notario, T., Pagani, D., Petrini, G., Poma, I., Quaranta, F., Randazzo, B., Ruisi, P., Signor, M., Viola, P., Virdis, A., and Tagliaferri, I.

Subjects
confronto varietale, Adattabilità ambientale, Triticale, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Abstract

La scarsità di precipitazioni ha determinato una maggiore sanità della granella dalla ruggine gialla e bruna in generale in tutta Italia. Le produzioni sono risultate di 7,4 t/ha al Nord, 5,2 al Centro (entrambe maggiori del 2016, dove risultavano, rispettivamente, di 6,5 e 4,6 t/ha) e di 4,4 t/ha al Sud e Isole, leggermente inferiore al 2016 (4,6 t/ha)

Published
2017

40. Quali varietà di triticale seminare nel 2016-2017

Author

Faccini N., Cattivelli L., Alberici R., Baronchelli M., Barbiani G., Cacciatori P., Codianni P., D’Ercole M., Delbono S., Faeti V., Fecondo G., Fornara M., Fuselli D., Ghizzoni R., Giunta F., Manca G., Marino A., Mazzon V., Notario T., Pagani D., Pruneddu G., Petrini A., Quaranta F., Randazzo B., Signor M., Viola P., Virdis A., Tagliaferri I., DI MICELI, Giuseppe, FRENDA, Alfonso Salvatore, POMA, Ignazio, RUISI, Paolo, Faccini N. (coordinatore), Cattivelli L. (coordinatore), Alberici R., Baronchelli M., Barbiani G., Cacciatori P., Codianni P., D’Ercole M., Delbono S., Di Miceli G., Faeti V., Fecondo G., Fornara M., Frenda A.S., Fuselli D., Ghizzoni R., Giunta F., Manca G., Marino A., Mazzon V., Notario T., Pagani D., Pruneddu G., Petrini A., Poma I., Quaranta F., Randazzo B., Ruisi P., Signor M., Viola P., Virdis A., and Tagliaferri I.

Subjects
Valutazione varietale nazionale, National varietal evaluation, Triticale, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Abstract

Significativi attacchi di ruggine gialla associati a scarse precipitazioni sulle Isole e a diffusi fenomeni di allettamento al Centro e al Nord hanno influito negativamente su tutte le medie produttive. Le rese sono pertanto state inferiori rispetto al 2015, con 6,5 t/ha al Nord, 4,6 al Centro e 3,5 al Sud e Isole

Published
2016

41. Orzo: buoni risultati produttivi nonostante i mesi siccitosi

Author

Cattivelli, L., Faccini, L., Gianinetti, A., Alberici, R., Amato, G., Anastasi, U., Attene, G., Baravelli, M., Barbiani, G., Baronchelli, M., Belocchi, A., Bonciarelli, U., Cacciatori, P., Civitella, D., Codianni, P., D'Ercole, M., De Francesco, L., Delbono, S., Donadeo, G., Faeti, V., Fecondo, G., Fina, C., Fornara, M., Frenda, A. S., Fuselli, D., Ghizzoni, R., Giambalvo, D., Invernizzi, C., Licciardello, S., Lorenzetti, M. C., Marino, A., Mastrorilli, M., Mazzieri, G., Mazzon, V., Monti, M, Moscaritolo, S., Notario, T., Pagani, D., Pala, T., Palumbo, M., Petrini, A., Pilati, A., Poma, I., Pons, R., Preiti, G., Quaranta, F., Randazzo, B, Reggiani, F., Rizzo, G., Rodriguez, M., Romeo, M., Ruisi, P., Sarno, M., Scarcella, M., Sciacca, F., Signor, M., Tagliaferri, I., Venezia, G., Viola, P., Virdis, A., Virgillito, S., and Virzì, N.

Subjects
genotipi, feed barley, orzo, orzo zootecnico, feed barley, varietà, genotipi, orzo, orzo zootecnico, varietà
Published
2017

42. Quality of Life After Prostate Cancer Diagnosis: Data from the Pros-IT CNR

Author

Gacci, M., Noale, M., Artibani, W., Bassi, P. F., Bertoni, F., Bracarda, S., Conti, G. N., Corvo, R., Graziotti, P., Magrini, S. M., Mirone, V., Montironi, R., Muto, G., Pecoraro, S., Porreca, A., Ricardi, U., Russi, E., Tubaro, A., Zagonel, V., Crepaldi, G., Maggi, S., Rita, A. A., Enrica, A., Alessandro, A., Cynthia, A., Michele, B., Franco, B., Lilia, B., Salvina, B., Sara, B., Umberto, B., Carlotta, B., Rita, B., Stefania, B., Alfredo, B., Marco, B., Roberto, B., Valentina, B., Davide, B., Giuseppe, B., Pierluigi, B., Maurizio, B., Alessio, B., Giorgio, B., Eugenio, B., Alberto, B., Michela, B., Consuelo, B., Giovanni, C., Michela, C., Giuseppe, C., Giorgio, C., Emanuele, C., Elisabetta, C., Gianpiero, C., Susanna, C., Francesco, C., Dario, C. F., Ofelia, C., Antonio, C., Tommaso, C., Claudia, C., Devis, C., Franco, C., Matteo, C., Paolo, C., Fiorenza, C., Luigi, C., de Nunzio, C., Olga, C., D'Angelillo, R., Luigi, D. P., Daniele, D., David, D., Matteo, D., Michele, D. A., Paolo, D. A., Ottavio, D. C., Bernardino, D. C., Antonello, D. L., Stefano, D. L., Agostina, D. S., Lucrezia, D. C., Claudio, D. E., Anna, D., Beatrice, D., Nadia, D. M., Andrea, D. S., Calogero, D. S., Danilo, D. T., Giuseppe, D., Sara, F., Giuseppe, F., Paolo, F., Ilaria, F., Francesco, F., Matteo, F., Andrei, F., Giulio, F., Giovanni, F., Pietro, G., Maria, G., Elisabetta, G., Giovanni, G. P., Alessandro, G., Laura, G., Giuseppe, G., Paolo, G., Alessia, G., Cesare, G., Alberto, G., Dorijan, H., Ciro, I., Gianluca, I., Cinzia, I., Corrado, I., Pierdaniele, L. M., Enza, L., Luciana, L., Grazia, L., Fabiola, L., Giovanni, L., Roberto, L., Frank, L., Riccardo, L., Jon AJ, L., Mario, L. G., Nicola, M., Francesca, M., Michele, M., Gianluca, M., Giovanni, M., Giovanna, M., Luigi, M., Luisa, M., Mario, M. A., Antonietta, M., Salvino, M., Stefano, M., Gloria, M., Adele, M., Ercole, M., Serena, M., Rosa, M., Giorgio, M., Emanuele, M., Franco, M., Giampaolo, M., Giuseppe, M., Gregorio, M., Daniela, M., Paolo, M., Giorgio, N., Augusto, N. C. L., Mattia, N., Maria, N., Marco, O., Carmela, P., Isabella, P., Alessandro, P., Paolo, P., Nicola, P., Martina, P., Francesco, P., Antonio, P., Valerio, P., Angelo, P., Caterina, P., Giorgio, P., Elisabetta, P., Benito, P. A., Dario, P., Armin, P., Giuseppe, R., Andrea, R., Franco, R. D., Valentina, R., Marco, R., Paola, R. M., Roberto, S., Anna, S., Michele, S., Riccardo, S., Sarah, S., Vittorio, S. G., Mauro, S., Marcello, S., Sciarra, A., Carmine, S., Tindaro, S., Salvatore, S., Oscar, S., Armando, S., Sergio, S., Andrea, S. M., Giovanni, S., Franco, S., Simeone, Claudio, Valeria, S., Girolamo, S., Giulio, S. M., Luigi, S., Vincenzo, T., Mariastella, T., Luca, T., Alberto, T., Eolo, T. L., Lucio, T., Carlo, T., Lidia, T., Marcello, T., Daniele, U., Riccardo, V., Maurizio, V., Elisabetta, V., Alessandro, V., Stefano, Z., Guglielmo, Z., Giampaolo, Z., Gacci, Mauro, Noale, Marianna, Artibani, Walter, Bassi, Pier Francesco, Bertoni, Filippo, Bracarda, Sergio, Conti, Giario Natale, Corvò, Renzo, Graziotti, Pierpaolo, Magrini, Stefano Maria, Mirone, Vincenzo, Montironi, Rodolfo, Muto, Giovanni, Pecoraro, Stefano, Porreca, Angelo, Ricardi, Umberto, Russi, Elvio, Tubaro, Andrea, Zagonel, Vittorina, Crepaldi, Gaetano, and Maggi, Stefania

Subjects
Oncology, Male, medicine.medical_specialty, Urology, 030232 urology & nephrology, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Quality of life (healthcare), Aged, Humans, Italy, Middle Aged, Prospective Studies, Prostatic Neoplasms, Quality of Life, Internal medicine, medicine, skin and connective tissue diseases, business.industry, medicine.disease, humanities, 030220 oncology & carcinogenesis, cardiovascular system, sense organs, business, circulatory and respiratory physiology
Abstract

Pros-IT CNR study provides a real-life report on changes in quality of life 6 mo after the diagnosis of prostate cancer.

Published
2017

43. Orzo da malto, quali varietà scegliere

Author

Cattivelli, L, Faccini, N, Gianinetti, A, Alberici, R, AMATO, Gaetano, Ara, A, Attene, G, Baravelli, M, Barbiani, G, Baronchelli, M, Belocchi, A, Bonciarelli, U, Cacciatori, P, Codianni, P, Colonna, M, D’Ercole, M, Delbono, S, Demontis, A, Donadeo, G, Faeti, V, Fecondo, G, Fina, C, Fornara, M, Franzoni, M, FRENDA, Alfonso Salvatore, Fuselli, D, Ghizzoni, R, GIAMBALVO, Dario, Giausa, S, Innocenti, A, Invernizzi, C, Licciardello, S, Lombardo, MG, Lorenzetti, MC, Manca, G, Marino, A, Mattiolo, E, Mastrorilli, M, Mazzieri, G, Mazzon, V, Notario, T, Pagani, D, Palumbo, M, Petrini, A, Pilati, A, POMA, Ignazio, Pons, R, Preiti, G, Quaranta, F, Randazzo, B, Ravaglia, S, Reggiani, F, Rodriguez, M, Rosta, R, RUISI, Paolo, SAIA, Sergio, SARNO, Mauro, Scarcella, M, Scrosati, M, Severi, D, Signor, M, Tagliaferri, I, Tassi, D, VENEZIA, Giacomo, Viola, P, Virdis, A, Virzì, N., Cattivelli, L (coord.), Faccini, N (coord.), Gianinetti, A (coord.), Alberici, R, Amato, G, Ara, A, Attene, G, Baravelli, M, Barbiani, G, Baronchelli, M, Belocchi, A, Bonciarelli, U, Cacciatori, P, Codianni, P, Colonna, M, D’Ercole, M, Delbono, S, Demontis, A, Donadeo, G, Faeti, V, Fecondo, G, Fina, C, Fornara, M, Franzoni, M, Frenda, AS, Fuselli, D, Ghizzoni, R, Giambalvo, D, Giausa, S, Innocenti, A, Invernizzi, C, Licciardello, S, Lombardo, MG, Lorenzetti, MC, Manca, G, Marino, A, Mattiolo, E, Mastrorilli, M, Mazzieri, G, Mazzon, V, Notario, T, Pagani, D, Palumbo, M, Petrini, A, Pilati, A, Poma, I, Pons, R, Preiti, G, Quaranta, F, Randazzo, B, Ravaglia, S, Reggiani, F, Rodriguez, M, Rosta, R, Ruisi, P, Saia, S, Sarno, M, Scarcella, M, Scrosati, M, Severi, D, Signor, M, Tagliaferri, I, Tassi, D, Venezia, G, Viola, P, Virdis, A, and Virzì, N

Subjects
Confronto varietale, Orzo da malto, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Abstract

In generale, il 2015 è stato un anno decisamente diversificato per quanto riguarda le produzioni, ma certamente più favorevole per la coltura dell’orzo primaverile al Centro-Nord, che dopo due anni negativi si riallinea al 2012 con una media produttiva di 5,3 t/ha.

Published
2015

44. Triticale: quale varietà scegliere per le prossime semine

Author

Faccini, N, Cattivelli, L, Alberici, R, Baroncelli, M, Cacciatori, P, Codianni, P, D'Ercole, M, Delbono, S, DI MICELI, Giuseppe, Faeti, V, Fecondo, G, Fornara, M, FRENDA, Alfonso Salvatore, Fuselli, D, Ghizzoni, R, Giunta, F, Licciardello, S, Magalesi, G, Manca, G, Marino, A, Notario, T, Pagani, D, Palumbo, M, Petrini, A, POMA, Ignazio, Quaranta, F, Randazzo, B, Ravaglia, S, RUISI, Paolo, Signor, M, Viola, P, Virdis, A, Virzì, N, Tagliaferri, I., Faccini, N (coord), Cattivelli, L (coord), Alberici, R, Baroncelli, M, Cacciatori, P, Codianni, P, D'Ercole, M, Delbono, S, Di Miceli, G, Faeti, V, Fecondo, G, Fornara, M, Frenda, AS, Fuselli, D, Ghizzoni, R, Giunta, F, Licciardello, S, Magalesi, G, Manca, G, Marino, A, Notario, T, Pagani, D, Palumbo, M, Petrini, A, Poma, I, Quaranta, F, Randazzo, B, Ravaglia, S, Ruisi, P, Signor, M, Viola, P, Virdis, A, Virzì, N, and Tagliaferri, I

Subjects
Confronto varietale, Triticale, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Abstract

La variabilità dei risultati è dovuta principalmente ad alcune avversità, tra le quali ruggine gialla e bruna. Le varietà consigliate sono 12 per l’areale Nord, 15 per il Centro e 12 per il Sud e le Isole. Il potenziale produttivo di questi gruppi varietali risulta rispettivamente di 7,1 t/ha al Nord, 5,8 t/ha al Centro e 4,9 t/ha nel Sud e Isole.

Published
2015

45. Orzo da zootecnia: ripresa al Centro, cali al Sud

Author

Cattivelli, L, Faccini, N, Gianinetti, A, Alberici, R, AMATO, Gaetano, Ara, A, Attene, G, Baravelli, M, Barbiani, G, Baronchelli, M, Belocchi, A, Bonciarelli, U, Cacciatori, P, Codianni, P, Colonna, M, D’Ercole, M, Delbono, S, Demontis, A, Donadeo, G, Faeti, V, Fecondo, G, Fina, C, Fornara, M, Franzoni, M, FRENDA, Alfonso Salvatore, Fuselli, D, Ghizzoni, R, GIAMBALVO, Dario, Giausa, S, Innocenti, A, Invernizzi, C, Licciardello, S, Lombardo, MG, Lorenzetti, MC, Manca, G, Marino, A, Mattiolo, E, Mastrorilli, M, Mazzieri, G, Mazzon, V, Notario, T, Pagani, D, Palumbo, M, Petrini, A, Pilati, A, POMA, Ignazio, Pons, R, Preiti, G, Quaranta, F, Randazzo, B, Ravaglia, S, Reggiani, F, Rodriguez, M, Rosta, R, RUISI, Paolo, SAIA, Sergio, SARNO, Mauro, Scarcella, M, Scrosati, M, Severi, D, Signor, M, Tagliaferri, I, Tassi, D, VENEZIA, Giacomo, Viola, P, Virdis, A, Virzì, N., Cattivelli, L (coord.), Faccini, N (coord.), Gianinetti, A (coord.), Alberici, R, Amato, G, Ara, A, Attene, G, Baravelli, M, Barbiani, G, Baronchelli, M, Belocchi, A, Bonciarelli, U, Cacciatori, P, Codianni, P, Colonna, M, D’Ercole, M, Delbono, S, Demontis, A, Donadeo, G, Faeti, V, Fecondo, G, Fina, C, Fornara, M, Franzoni, M, Frenda, AS, Fuselli, D, Ghizzoni, R, Giambalvo, D, Giausa, S, Innocenti, A, Invernizzi, C, Licciardello, S, Lombardo, MG, Lorenzetti, MC, Manca, G, Marino, A, Mattiolo, E, Mastrorilli, M, Mazzieri, G, Mazzon, V, Notario, T, Pagani, D, Palumbo, M, Petrini, A, Pilati, A, Poma, I, Pons, R, Preiti, G, Quaranta, F, Randazzo, B, Ravaglia, S, Reggiani, F, Rodriguez, M, Rosta, R, Ruisi, P, Saia, S, Sarno, M, Scarcella, M, Scrosati, M, Severi, D, Signor, M, Tagliaferri, I, Tassi, D, Venezia, G, Viola, P, Virdis, A, and Virzì, N

Subjects
Confronto varietale, Orzo da zootecnica, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Abstract

La rete delle prove nazionali di orzo da zootecnia per l’annata 2014-2015 mostra risultati molto diversi a seconda della località. La media produttiva al Nord risulta di 6,5 t/ha come lo scorso anno, al Centro in deciso aumento con 6,7 t/ha, mentre al Sud la produttività evidenzia una perdita di 1 t/ha.

Published
2015

46. Varietà di orzo zootecnico: bene al Sud, meno al Nord

Author

Cattivelli, L, Faccini, N, Gianinetti, A, Alberici, R, Anastasi, U, Attene, G, Baravelli, M, Barbiani, G, Baronchelli, M, Belocchi, A, Bonciarelli, U, Cacciatori, P, Caprara, F, Codianni, P, Colonna, M, D’Ercole, M, Delbono, S, Demontis, A, Faeti, V, Fecondo, G, Ferrero, C, Fornara, M, Fuselli, D, Ghizzoni, R, Innocenti, A, Invernizzi, C, Lombardo, MG, Lorenzetti, MC, Manca, G, Marino, A, Mattiolo, E, Mazzieri, G, Monti, M, Notario, T, Pagani, D, Petrini, A, Pilati, A, Piredda, A, Pons, R, Preiti, G, Pristeri, A, Quaranta, F, Randazzo, B, Ravaglia, S, Reggiani, F, Rodriguez, M, Romeo, M, Rosta, R, Scrosati, M, Severi, D, Signor, M, Tagliaferri, I, Tassi, D, Viola, P, Virdis, A, Virgillito, S, Virzì, N., AMATO, Gaetano, FRENDA, Alfonso Salvatore, GIAMBALVO, Dario, POMA, Ignazio, RUISI, Paolo, SAIA, Sergio, SARNO, Mauro, VENEZIA, Giacomo, Cattivelli, L, Faccini, N, Gianinetti, A, Alberici, R, Amato, G, Anastasi, U, Attene, G, Baravelli, M, Barbiani, G, Baronchelli, M, Belocchi, A, Bonciarelli, U, Cacciatori, P, Caprara, F, Codianni, P, Colonna, M, D’Ercole, M, Delbono, S, Demontis, A, Faeti, V, Fecondo, G, Ferrero, C, Fornara, M, Frenda, AS, Fuselli, D, Ghizzoni, R, Giambalvo, D, Innocenti, A, Invernizzi, C, Lombardo, MG, Lorenzetti, MC, Manca, G, Marino, A, Mattiolo, E, Mazzieri, G, Monti, M, Notario, T, Pagani, D, Petrini, A, Pilati, A, Piredda, A, Poma, I, Pons, R, Preiti, G, Pristeri, A, Quaranta, F, Randazzo, B, Ravaglia, S, Reggiani, F, Rodriguez, M, Romeo, M, Rosta, R, Ruisi, P, Saia, S, Sarno, M, Scrosati, M, Severi, D, Signor, M, Tagliaferri, I, Tassi, D, Venezia, G, Viola, P, Virdis, A, Virgillito, S, and Virzì, N

Subjects
Orzo zootecnico, Varietà, Prove nazionali, Nord, Centro, Sud e Isole, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Abstract

Al Nord la media dell' areale è stata di 6,5 t/ha in ripresa rispetto al tracollo della scorsa annata, al Centro è risultata di sole 5,1 t/ha, dato al di sotto delle potenzialità produttive; al Sud la produttività media è stata di 5,7 t/ha, un ottimo risultato che riporta l' areale su livelli elevati

Published
2014

47. Al centro-nord vince la pioggia, bene solo il Meridione

Author

Cattivelli, L, Faccini, N, Gianinetti, A, Alberici, R, Anastasi, U, Attene, G, Baravelli, M, Barbiani, G, Baronchelli, M, Belocchi, A, Bonciarelli, U, Cacciatori, P, Caprara, F, Codianni, P, Colonna, M, D’Ercole, M, Delbono, S, Demontis, A, Faeti, V, Fecondo, G, Ferrero, C, Fornara, M, Fuselli, D, Ghizzoni, R, Innocenti, A, Invernizzi, C, Lombardo, MG, Lorenzetti, MC, Manca, G, Marino, A, Mattiolo, E, Mazzieri, G, Monti, M, Notario, T, Pagani, D, Petrini, A, Pilati, A, Piredda, A, Pons, R, Preiti, G, Pristeri, A, Quaranta, F, Randazzo, B, Ravaglia, S, Reggiani, F, Rodriguez, M, Romeo, M, Rosta, R, Scrosati, M, Severi, D, Signor, M, Tagliaferri, I, Tassi, D, Viola, P, Virdis, A, Virgillito, S, Virzì, N., AMATO, Gaetano, FRENDA, Alfonso Salvatore, GIAMBALVO, Dario, POMA, Ignazio, RUISI, Paolo, SAIA, Sergio, SARNO, Mauro, VENEZIA, Giacomo, Cattivelli, L, Faccini, N, Gianinetti, A, Alberici, R, Amato, G, Anastasi, U, Attene, G, Baravelli, M, Barbiani, G, Baronchelli, M, Belocchi, A, Bonciarelli, U, Cacciatori, P, Caprara, F, Codianni, P, Colonna, M, D’Ercole, M, Delbono, S, Demontis, A, Faeti, V, Fecondo, G, Ferrero, C, Fornara, M, Frenda, AS, Fuselli, D, Ghizzoni, R, Giambalvo, D, Innocenti, A, Invernizzi, C, Lombardo, MG, Lorenzetti, MC, Manca, G, Marino, A, Mattiolo, E, Mazzieri, G, Monti, M, Notario, T, Pagani, D, Petrini, A, Pilati, A, Piredda, A, Poma, I, Pons, R, Preiti, G, Pristeri, A, Quaranta, F, Randazzo, B, Ravaglia, S, Reggiani, F, Rodriguez, M, Romeo, M, Rosta, R, Ruisi, P, Saia, S, Sarno, M, Scrosati, M, Severi, D, Signor, M, Tagliaferri, I, Tassi, D, Venezia, G, Viola, P, Virdis, A, Virgillito, S, and Virzì, N

Subjects
Orzo da malto, Orzo da zootecnia, Varietà, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Published
2014

48. Le varietà per l’orzo da malto

Author

Cattivelli, L, Faccini, N, Gianinetti, A, Alberici, R, Anastasi, U, Attene, G, Baravelli, M, Barbiani, G, Baronchelli, M, Belocchi, A, Bonciarelli, U, Cacciatori, P, Caprara, F, Codianni, P, Colonna, M, D’Ercole, M, Delbono, S, Demontis, A, Faeti, V, Fecondo, G, Ferrero, C, Fornara, M, Fuselli, D, Ghizzoni, R, Innocenti, A, Invernizzi, C, Lombardo, MG, Lorenzetti, MC, Manca, G, Marino, A, Mattiolo, E, Mazzieri, G, Monti, M, Notario, T, Pagani, D, Petrini, A, Pilati, A, Piredda, A, Pons, R, Preiti, G, Pristeri, A, Quaranta, F, Randazzo, B, Ravaglia, S, Reggiani, F, Rodriguez, M, Romeo, M, Rosta, R, Scrosati, M, Severi, D, Signor, M, Tagliaferri, I, Tassi, D, Viola, P, Virdis, A, Virgillito, S, Virzì, N., AMATO, Gaetano, FRENDA, Alfonso Salvatore, GIAMBALVO, Dario, POMA, Ignazio, RUISI, Paolo, SAIA, Sergio, SARNO, Mauro, VENEZIA, Giacomo, Cattivelli, L, Faccini, N, Gianinetti, A, Alberici, R, Amato, G, Anastasi, U, Attene, G, Baravelli, M, Barbiani, G, Baronchelli, M, Belocchi, A, Bonciarelli, U, Cacciatori, P, Caprara, F, Codianni, P, Colonna, M, D’Ercole, M, Delbono, S, Demontis, A, Faeti, V, Fecondo, G, Ferrero, C, Fornara, M, Frenda, AS, Fuselli, D, Ghizzoni, R, Giambalvo, D, Innocenti, A, Invernizzi, C, Lombardo, MG, Lorenzetti, MC, Manca, G, Marino, A, Mattiolo, E, Mazzieri, G, Monti, M, Notario, T, Pagani, D, Petrini, A, Pilati, A, Piredda, A, Poma, I, Pons, R, Preiti, G, Pristeri, A, Quaranta, F, Randazzo, B, Ravaglia, S, Reggiani, F, Rodriguez, M, Romeo, M, Rosta, R, Ruisi, P, Saia, S, Sarno, M, Scrosati, M, Severi, D, Signor, M, Tagliaferri, I, Tassi, D, Venezia, G, Viola, P, Virdis, A, Virgillito, S, and Virzì, N

Subjects
Orzo da malto, Varietà, Prove nazionali, Nord, Centro, Sud e Isole, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Abstract

Per il Centro-sud e Isole la produzione ha superato di 0,3 t/ha quella dell’annata precedente attestandosi a 4,8 t/ha, mentre per il Centro-nord la media è stata di sole 3,1 t/ha. La sofferenza della coltura si è manifestata chiaramente anche in termini di ritardo della spigatura, avvenuta nell’ultima decade di maggio

Published
2014

49. Triticale: le varietà per le prossime semine

Author

Faccini, N, Cattivelli, L, Alberici, R, Baroncelli, M, Cacciatori, P, Codianni, P, D'Ercole, M, Delbono, S, Faeti, V, Fecondo, G, Fornara, M, Fuselli, D, Ghizzoni, R, Manca, G, MArini, A, Notario, T, PAgani, D, Palumbo, M, Petrini, A, Puleo, A, Quaranta, F, Randazzo, B, Ravaglia, S, Sestili, A, Signor, M, Viola, P, Virdis, A, Tagliaferri, I., DI MICELI, Giuseppe, FRENDA, Alfonso Salvatore, POMA, Ignazio, RUISI, Paolo, Faccini, N (coord), Cattivelli, L (coord), Alberici, R, Baroncelli, M, Cacciatori, P, Codianni, P, D'Ercole, M, Delbono, S, Di Miceli, G, Faeti, V, Fecondo, G, Fornara, M, Frenda, AS, Fuselli, D, Ghizzoni, R, Manca, G, MArini, A, Notario, T, PAgani, D, Palumbo, M, Petrini, A, Poma, I, Puleo, A, Quaranta, F, Randazzo, B, Ravaglia, S, Ruisi, P, Sestili, A, Signor, M, Viola, P, Virdis, A, and Tagliaferri, I.

Subjects
Varietal comparison, Confronto varietale, Triticale, Settore AGR/02 - Agronomia E Coltivazioni Erbacee
Published
2014

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