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1. Emergency front-of-neck access in cardiac arrest: A scoping review

Author

Berg, Katherine M., Böttiger, Bernd W., Chia, Yew Woon, Crowley, Conor, D'Arrigo, Sonia, Deakin, Charles D., Fernando, Shannon M., Garg, Rakesh, Granfeldt, Asger, Grunau, Brian, Hirsch, Karen G., Holmberg, Mathias J., Lavonas, Eric, Leong, Carrie, Kudenchuk, Peter J., Morley, Peter, Moskowitz, Ari, Neumar, Robert, Nicholson, Tonia C., Nikolaou, Nikolaos, Nolan, Jerry P., O'Neil, Brian, Ohshimo, Shinichiro, Parr, Michael, Pocock, Helen, Sandroni, Claudio, Scquizzato, Tommaso, Skrifvars, Markus, Vlok, Neville, Welsford, Michelle, Zelop, Carolyn, Aljanoubi, Mohammed, Almazrua, Abdulkarim A., Johnson, Samantha, Drennan, Ian R, Reynolds, Joshua C., Soar, Jasmeet, and Couper, Keith

Published
2024
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3. ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

Author

Grasselli, Giacomo, Calfee, Carolyn S., Camporota, Luigi, Poole, Daniele, Amato, Marcelo B. P., Antonelli, Massimo, Arabi, Yaseen M., Baroncelli, Francesca, Beitler, Jeremy R., Bellani, Giacomo, Bellingan, Geoff, Blackwood, Bronagh, Bos, Lieuwe D. J., Brochard, Laurent, Brodie, Daniel, Burns, Karen E. A., Combes, Alain, D’Arrigo, Sonia, De Backer, Daniel, Demoule, Alexandre, Einav, Sharon, Fan, Eddy, Ferguson, Niall D., Frat, Jean-Pierre, Gattinoni, Luciano, Guérin, Claude, Herridge, Margaret S., Hodgson, Carol, Hough, Catherine L., Jaber, Samir, Juffermans, Nicole P., Karagiannidis, Christian, Kesecioglu, Jozef, Kwizera, Arthur, Laffey, John G., Mancebo, Jordi, Matthay, Michael A., McAuley, Daniel F., Mercat, Alain, Meyer, Nuala J., Moss, Marc, Munshi, Laveena, Myatra, Sheila N., Ng Gong, Michelle, Papazian, Laurent, Patel, Bhakti K., Pellegrini, Mariangela, Perner, Anders, Pesenti, Antonio, Piquilloud, Lise, Qiu, Haibo, Ranieri, Marco V., Riviello, Elisabeth, Slutsky, Arthur S., Stapleton, Renee D., Summers, Charlotte, Thompson, Taylor B., Valente Barbas, Carmen S., Villar, Jesús, Ware, Lorraine B., Weiss, Björn, Zampieri, Fernando G., Azoulay, Elie, and Cecconi, Maurizio

Published
2023
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5. Incidence, characteristics, and outcome of out-of-hospital cardiac arrest in Italy: A systematic review and meta-analysis

Author

Bertoncello, Francesco, Canalini, Alberto, Colelli, Stefano, Conti, Giuseppe, Giacometti, Maurizio, Giuliani, Giovanni, Graziano, Alessandro, Mina, Andrea, Orazio, Silvia, Paoli, Andrea, Peratoner, Alberto, Pegani, Carlo, Roncarati, Andrea, Sabetta, Cesare, Savastano, Simone, Stella, Federica, Varutti, Rosanna, Verginella, Francesca, Zuliani, Michele, Scquizzato, Tommaso, Gamberini, Lorenzo, D'Arrigo, Sonia, Galazzi, Alessandro, Babini, Giovanni, Losiggio, Rosario, Imbriaco, Guglielmo, Fumagalli, Francesca, Cucino, Alberto, Landoni, Giovanni, Scapigliati, Andrea, Ristagno, Giuseppe, and Semeraro, Federico

Published
2022
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6. Prediction of good neurological outcome in comatose survivors of cardiac arrest: a systematic review

Author

Sandroni, Claudio, D'Arrigo, Sonia, Cacciola, Sofia, Hoedemaekers, Cornelia W. E., Westhall, Erik, Kamps, Marlijn J. A., and Taccone, Fabio S.

Subjects
Medical research, Medicine, Experimental, Coma -- Prognosis, Cardiac arrest -- Prognosis, Electroencephalography, Neurophysiology, Health care industry
Abstract

Purpose To assess the ability of clinical examination, blood biomarkers, electrophysiology or neuroimaging assessed within 7 days from return of spontaneous circulation (ROSC) to predict good neurological outcome, defined as no, mild, or moderate disability (CPC 1-2 or mRS 0-3) at discharge from intensive care unit or later, in comatose adult survivors from cardiac arrest (CA). Methods PubMed, EMBASE, Web of Science and the Cochrane Database of Systematic Reviews were searched. Sensitivity and specificity for good outcome were calculated for each predictor. The risk of bias was assessed using the QUIPS tool. Results A total of 37 studies were included. Due to heterogeneities in recording times, predictor thresholds, and definition of some predictors, meta-analysis was not performed. A withdrawal or localisation motor response to pain immediately or at 72-96 h after ROSC, normal blood values of neuron-specific enolase (NSE) at 24 h-72 h after ROSC, a short-latency somatosensory evoked potentials (SSEPs) N20 wave amplitude > 4 [micro]V or a continuous background without discharges on electroencephalogram (EEG) within 72 h from ROSC, and absent diffusion restriction in the cortex or deep grey matter on MRI on days 2-7 after ROSC predicted good neurological outcome with more than 80% specificity and a sensitivity above 40% in most studies. Most studies had moderate or high risk of bias. Conclusions In comatose cardiac arrest survivors, clinical, biomarker, electrophysiology, and imaging studies identified patients destined to a good neurological outcome with high specificity within the first week after cardiac arrest (CA)., Author(s): Claudio Sandroni [sup.1] [sup.2], Sonia D'Arrigo [sup.1], Sofia Cacciola [sup.1], Cornelia W. E. Hoedemaekers [sup.3], Erik Westhall [sup.4], Marlijn J. A. Kamps [sup.5], Fabio S. Taccone [sup.6], Daniele Poole [...]

Published
2022
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12. Gas conditioning during helmet noninvasive ventilation: effect on comfort, gas exchange, inspiratory effort, transpulmonary pressure and patient–ventilator interaction

Author

Bongiovanni, Filippo, Grieco, Domenico Luca, Anzellotti, Gian Marco, Menga, Luca Salvatore, Michi, Teresa, Cesarano, Melania, Raggi, Valeria, De Bartolomeo, Cecilia, Mura, Benedetta, Mercurio, Giovanna, D’Arrigo, Sonia, Bello, Giuseppe, Maviglia, Riccardo, Pennisi, Mariano Alberto, and Antonelli, Massimo

Published
2021
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24. A new pressure-based device for tip navigation and tip location during central venous catheterization: A prospective clinical study on a cohort of 136 adult patients

Author

D’Arrigo, Sonia, Emoli, Alessandro, Marche, Bruno, and Pittiruti, Mauro

Abstract

Introduction: According to current guidelines, tip location of peripherally inserted central catheters (PICCs) should be verified during insertion, preferably using non-invasive methods such as intracavitary ECG (IC-ECG) or echocardiography. An interesting new option is represented by a new pressure-based device, the CatFinder System (CFS), which might be theoretically useful also for tip navigation.Methods: We planned a single-center, prospective, non-randomized trial on adult patients requiring PICC insertion, using simultaneously CFS and IC-ECG, with the purpose of verifying the applicability, feasibility, safety, and accuracy of CFS for intra-procedural tip location. Patients with known ECG abnormalities or cardiac diseases of any type were excluded. The ability of CFS to assess wrong directions of the catheter during insertion (tip navigation) was evaluated by comparison with ultrasound scan.Results: Out of 136 enrolled adult patients, CFS was found to be applicable in 131 cases (five cases were excluded because of ECG abnormalities) and feasible in 111 cases (in 20 cases, tip location by CFS could not be carried out because of technical issues). There were no complications directly or indirectly related to the CFS maneuvers. Using IC-ECG as a comparison, 87 tips placed by CFS were within 2 cm from the target, 17 were >2 cm from target. In seven cases, CFS was able to detect a wrong direction (to the ipsilateral internal jugular vein), as confirmed by ultrasound.Conclusion: Applicability of CFS in patients with sinus rhythm was 96.3%, feasibility was 84.7%, and safety was 100%. If compared to IC-ECG, accuracy was 83.6% (accepting an error <2 cm) and 96.1% (for an error <3 cm). Unacceptable tip positions (>3 cm) were 3.8% (the tip was too high inside the SVC). This study confirms a possible future role of CFS for intra-procedural tip location and tip navigation, though its use cannot be currently recommended.

Published
2024
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27. Adult Advanced Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations

Author

Berg, Katherine M., Soar, Jasmeet, Andersen, Lars W., Böttiger, Bernd W., Cacciola, Sofia, Callaway, Clifton W., Couper, Keith, Cronberg, Tobias, D’Arrigo, Sonia, Deakin, Charles D., Donnino, Michael W., Drennan, Ian R., Granfeldt, Asger, Hoedemaekers, Cornelia W.E., Holmberg, Mathias J., Hsu, Cindy H., Kamps, Marlijn, Musiol, Szymon, Nation, Kevin J., Neumar, Robert W., Nicholson, Tonia, O’Neil, Brian J., Otto, Quentin, de Paiva, Edison Ferreira, Parr, Michael J.A., Reynolds, Joshua C., Sandroni, Claudio, Scholefield, Barnaby R., Skrifvars, Markus B., Wang, Tzong-Luen, Wetsch, Wolfgang A., Yeung, Joyce, Morley, Peter T., Morrison, Laurie J., Welsford, Michelle, Hazinski, Mary Fran, and Nolan, Jerry P.

Published
2020
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29. ESICM guidelines on acute respiratory distress syndrome:definition, phenotyping and respiratory support strategies

Author

Grasselli, Giacomo, Calfee, Carolyn S., Camporota, Luigi, Poole, Daniele, Amato, Marcelo B.P., Antonelli, Massimo, Arabi, Yaseen M., Baroncelli, Francesca, Beitler, Jeremy R., Bellani, Giacomo, Bellingan, Geoff, Blackwood, Bronagh, Bos, Lieuwe D.J., Brochard, Laurent, Brodie, Daniel, Burns, Karen E.A., Combes, Alain, D’Arrigo, Sonia, De Backer, Daniel, Demoule, Alexandre, Einav, Sharon, Fan, Eddy, Ferguson, Niall D., Frat, Jean Pierre, Gattinoni, Luciano, Guérin, Claude, Herridge, Margaret S., Hodgson, Carol, Hough, Catherine L., Jaber, Samir, Juffermans, Nicole P., Karagiannidis, Christian, Kesecioglu, Jozef, Kwizera, Arthur, Laffey, John G., Mancebo, Jordi, Matthay, Michael A., McAuley, Daniel F., Mercat, Alain, Meyer, Nuala J., Moss, Marc, Munshi, Laveena, Myatra, Sheila N., Ng Gong, Michelle, Papazian, Laurent, Patel, Bhakti K., Pellegrini, Mariangela, Perner, Anders, Pesenti, Antonio, Piquilloud, Lise, Grasselli, Giacomo, Calfee, Carolyn S., Camporota, Luigi, Poole, Daniele, Amato, Marcelo B.P., Antonelli, Massimo, Arabi, Yaseen M., Baroncelli, Francesca, Beitler, Jeremy R., Bellani, Giacomo, Bellingan, Geoff, Blackwood, Bronagh, Bos, Lieuwe D.J., Brochard, Laurent, Brodie, Daniel, Burns, Karen E.A., Combes, Alain, D’Arrigo, Sonia, De Backer, Daniel, Demoule, Alexandre, Einav, Sharon, Fan, Eddy, Ferguson, Niall D., Frat, Jean Pierre, Gattinoni, Luciano, Guérin, Claude, Herridge, Margaret S., Hodgson, Carol, Hough, Catherine L., Jaber, Samir, Juffermans, Nicole P., Karagiannidis, Christian, Kesecioglu, Jozef, Kwizera, Arthur, Laffey, John G., Mancebo, Jordi, Matthay, Michael A., McAuley, Daniel F., Mercat, Alain, Meyer, Nuala J., Moss, Marc, Munshi, Laveena, Myatra, Sheila N., Ng Gong, Michelle, Papazian, Laurent, Patel, Bhakti K., Pellegrini, Mariangela, Perner, Anders, Pesenti, Antonio, and Piquilloud, Lise

Abstract

The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult patients and to non-pharmacological respiratory support strategies across different aspects of acute respiratory distress syndrome (ARDS), including ARDS due to coronavirus disease 2019 (COVID-19). These guidelines were formulated by an international panel of clinical experts, one methodologist and patients’ representatives on behalf of the ESICM. The review was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and grade recommendations and the quality of reporting of each study based on the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) network guidelines. The CPG addressed 21 questions and formulates 21 recommendations on the following domains: (1) definition; (2) phenotyping, and respiratory support strategies including (3) high-flow nasal cannula oxygen (HFNO); (4) non-invasive ventilation (NIV); (5) tidal volume setting; (6) positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM); (7) prone positioning; (8) neuromuscular blockade, and (9) extracorporeal life support (ECLS). In addition, the CPG includes expert opinion on clinical practice and identifies the areas of future research.

Published
2023

30. Can carotid artery Doppler variations induced by the end-expiratory occlusion maneuver predict fluid responsiveness in septic shock patients?

Author

D'Arrigo, Sonia, Dell'Anna, Antonio Maria, Sandroni, Claudio, Messina, A., Cacciola, Sofia, Pacini, C., Antonelli, Massimo, D'Arrigo S. (ORCID:0000-0001-6740-3195), Dell'Anna A. M., Sandroni C. (ORCID:0000-0002-8878-2611), Cacciola S., Antonelli M. (ORCID:0000-0003-3007-1670), D'Arrigo, Sonia, Dell'Anna, Antonio Maria, Sandroni, Claudio, Messina, A., Cacciola, Sofia, Pacini, C., Antonelli, Massimo, D'Arrigo S. (ORCID:0000-0001-6740-3195), Dell'Anna A. M., Sandroni C. (ORCID:0000-0002-8878-2611), Cacciola S., and Antonelli M. (ORCID:0000-0003-3007-1670)

Abstract

Background: An increase in cardiac index (CI) during an end-expiratory occlusion test (EEOt) predicts fluid responsiveness in ventilated patients. However, if CI monitoring is unavailable or the echocardiographic window is difficult, using the carotid Doppler (CD) could be a feasible alternative to track CI changes. This study investigates whether changes in CD peak velocity (CDPV) and corrected flow time (cFT) during an EEOt were correlated with CI changes and if CDPV and cFT changes predicted fluid responsiveness in patients with septic shock. Methods: Prospective, single-center study in adults with hemodynamic instability. The CDPV and cFT on carotid artery Doppler and hemodynamic variables from the pulse contour analysis EV1000TM were recorded at baseline, during a 20-s EEOt, and after fluid challenge (500 mL). We defined responders as those who increased CI ≥ 15% after a fluid challenge. Results: We performed 44 measurements in 18 mechanically ventilated patients with septic shock and without arrhythmias. The fluid responsiveness rate was 43.2%. The changes in CDPV were significantly correlated with changes in CI during EEOt (r = 0.51 [0.26–0.71]). A significant, albeit lower correlation, was found for cFT (r = 0.35 [0.1–0.58]). An increase in CI ≥ 5.35% during EEOt predicted fluid responsiveness with 78.9% sensitivity and 91.7% specificity, with an area under the ROC curve (AUROC) of 0.85. An increase in CDPV ≥ 10.5% during an EEOt predicted fluid responsiveness with 96.2% specificity and 53.0% sensitivity with an AUROC of 0.74. Sixty-one percent of CDPV measurements (from − 13.5 to 9.5 cm/s) fell within the gray zone. The cFT changes during EEOt did not accurately predict fluid responsiveness. Conclusions: In septic shock patients without arrhythmias, an increase in CDPV greater than 10.5% during a 20-s EEOt predicted fluid responsiveness with > 95% specificity. Carotid Doppler combined with EEOt may help optimize preload when invasive hemodynami

Published
2023

31. Secondary malposition of a PICC-port due to heavy physical exercise: A case report

Author

D'Arrigo, Sonia, Annetta, Maria Giuseppina, Musaro, A., Distefano, M., Pittiruti, Mauro, D'Arrigo S. (ORCID:0000-0001-6740-3195), Annetta M. G. (ORCID:0000-0001-7574-1311), Pittiruti M. (ORCID:0000-0003-4541-7566), D'Arrigo, Sonia, Annetta, Maria Giuseppina, Musaro, A., Distefano, M., Pittiruti, Mauro, D'Arrigo S. (ORCID:0000-0001-6740-3195), Annetta M. G. (ORCID:0000-0001-7574-1311), and Pittiruti M. (ORCID:0000-0003-4541-7566)

Abstract

Physical exercise is often encouraged in cancer patients, mainly for the purpose of rehabilitation and for its psychological benefit. Some authors also suggest that exercise—specially in patient with peripherally inserted central venous access devices—may contribute to reduce the risk of catheter-related thrombosis. Still, the impact of physical exercise on the risk of device-related complications is not yet defined. We report a case of secondary migration of the tip of an arm port, caused by high-intensity exercise in a woman undergoing chemotherapy because of ovarian cancer. Tip migration was suspected because of malfunction (persistent withdrawal occlusion) and diagnosis established after ultrasound examination and chest x-ray. Even if exercise may yield benefit in the cancer patient on chemotherapy, the risk of mechanical complication of the venous access device—such as tip migration—should be considered in the case of high-intensity exercise.

Published
2023

32. Should we consider preoperative PICC insertion for adult patients undergoing major surgery?

Author

D'Arrigo, Sonia, Annetta, Maria Giuseppina, Iacobucci, Tiziana, Dottarelli, Alessandra, Pittiruti, Mauro, D'Arrigo S. (ORCID:0000-0001-6740-3195), Annetta M. G. (ORCID:0000-0001-7574-1311), Iacobucci T., Dottarelli A., Pittiruti M. (ORCID:0000-0003-4541-7566), D'Arrigo, Sonia, Annetta, Maria Giuseppina, Iacobucci, Tiziana, Dottarelli, Alessandra, Pittiruti, Mauro, D'Arrigo S. (ORCID:0000-0001-6740-3195), Annetta M. G. (ORCID:0000-0001-7574-1311), Iacobucci T., Dottarelli A., and Pittiruti M. (ORCID:0000-0003-4541-7566)

Abstract

n/a

Published
2023

33. Ultrasound-guided access to the axillary vein for implantation of cardiac implantable electronic devices: A systematic review and meta-analysis

Author

D'Arrigo, Sonia, Perna, Francesco, Annetta, Maria Giuseppina, Pittiruti, Mauro, D'Arrigo S. (ORCID:0000-0001-6740-3195), Perna F., Annetta M. G. (ORCID:0000-0001-7574-1311), Pittiruti M. (ORCID:0000-0003-4541-7566), D'Arrigo, Sonia, Perna, Francesco, Annetta, Maria Giuseppina, Pittiruti, Mauro, D'Arrigo S. (ORCID:0000-0001-6740-3195), Perna F., Annetta M. G. (ORCID:0000-0001-7574-1311), and Pittiruti M. (ORCID:0000-0003-4541-7566)

Abstract

The aims of our systematic review were to quantify the expected rate of procedural success, early and late complications during CIED implantation using US-guided puncture of the axillary vein and to perform a meta-analysis of those studies that compared the US technique (intervention) versus conventional techniques (control) in terms of complication rates. MEDLINE, ISI Web of Science, and EMBASE were searched for eligible studies. Pooled Odds Ratio (OR) and Pooled Mean Difference (PMD) for each predictor were calculated. The quality of evidence (QOE) was evaluated according to the GRADE guidelines. Thirteen studies were included a total of 2073 patients. The overall success of US-guided venipuncture for CIED implantation was 96.8%. As regards early complications, pneumothorax occurred in 0.19%, arterial puncture in 0.63%, and severe hematoma/bleeding requiring intervention in 1.1%. No cases of hemothorax, brachial plexus, or phrenic nerve injury were reported. As regards late complications, the incidence of pocket infection, venous thromboembolism, and leads dislodgement was respectively 0.4%, 0.8%, and 1.2%. In the meta-analysis (five studies), the intervention group (US-guided venipuncture) had a trend versus a lower likelihood of having a pneumothorax (0.19% vs 0.75%, p = 0.21), pocket hematoma (0.8% vs 1.7%, p = 0.32), infection (0.28% vs 1.05%, p = 0.29) than the control group, but this did not reach statistical significance. The overall QOE was low or very low. In conclusions we found that the US-guided axillary venipuncture for CIEDs implantation was associated with a low incidence of early and late complications and a steep learning curve.

Published
2023

34. An ultrasound-based technique in the management of totally implantable venous access devices with persistent withdrawal occlusion

Author

D'Arrigo, Sonia, Annetta, Maria Giuseppina, Pittiruti, Mauro, D'Arrigo S. (ORCID:0000-0001-6740-3195), Annetta M. G. (ORCID:0000-0001-7574-1311), Pittiruti M. (ORCID:0000-0003-4541-7566), D'Arrigo, Sonia, Annetta, Maria Giuseppina, Pittiruti, Mauro, D'Arrigo S. (ORCID:0000-0001-6740-3195), Annetta M. G. (ORCID:0000-0001-7574-1311), and Pittiruti M. (ORCID:0000-0003-4541-7566)

Abstract

Persistent withdrawal occlusion is a specific catheter malfunction characterized by inability to withdraw blood through the device while infusion is maintained. The main causes are fibroblastic sleeve and tip malposition (associated or not to venous thrombosis around the tip). All current guidelines recommend infusing vesicant/antiblastic drugs through a central venous port only after assessment of blood return. In PWO, blood return is impossible. We have recently started to assess the intravascular position of the tip and the delivery of the infusion in the proximity of the cavo-atrial junction utilizing transthoracic/subxiphoid ultrasound with the ‘bubble test’. We found that this is an easy, real-time, accurate and safe method for verifying the possibility of using a port for chemotherapy even in the absence of blood return, as it occurs with persistent withdrawal occlusion.

Published
2023

35. Incidence, characteristics, and outcome of out-of-hospital cardiac arrest in Italy: A systematic review and meta-analysis

Author

Scquizzato, Tommaso, primary, Gamberini, Lorenzo, additional, D'Arrigo, Sonia, additional, Galazzi, Alessandro, additional, Babini, Giovanni, additional, Losiggio, Rosario, additional, Imbriaco, Guglielmo, additional, Fumagalli, Francesca, additional, Cucino, Alberto, additional, Landoni, Giovanni, additional, Scapigliati, Andrea, additional, Ristagno, Giuseppe, additional, Semeraro, Federico, additional, Bertoncello, Francesco, additional, Canalini, Alberto, additional, Colelli, Stefano, additional, Conti, Giuseppe, additional, Giacometti, Maurizio, additional, Giuliani, Giovanni, additional, Graziano, Alessandro, additional, Mina, Andrea, additional, Orazio, Silvia, additional, Paoli, Andrea, additional, Peratoner, Alberto, additional, Pegani, Carlo, additional, Roncarati, Andrea, additional, Sabetta, Cesare, additional, Savastano, Simone, additional, Stella, Federica, additional, Varutti, Rosanna, additional, Verginella, Francesca, additional, and Zuliani, Michele, additional

Published
2022
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37. The rate of brain death and organ donation in patients resuscitated from cardiac arrest: a systematic review and meta-analysis

Author

Sandroni, Claudio, D'Arrigo, Sonia, Callaway, Clifton W., Cariou, Alain, Dragancea, Irina, Taccone, Fabio Silvio, and Antonelli, Massimo

Subjects
Transplantation of organs, tissues, etc. -- Analysis, Medical research -- Analysis, Medicine, Experimental -- Analysis, Brain death -- Analysis, Brain -- Injuries, Cardiac patients -- Analysis -- Injuries, Cardiac arrest -- Analysis, Donation of organs, tissues, etc. -- Analysis, Health care industry, Cochrane Database of Systematic Reviews (Online service)
Abstract

Background The occurrence of brain death in patients with hypoxic-ischaemic brain injury after resuscitation from cardiac arrest creates opportunities for organ donation. However, its prevalence is currently unknown. Methods Systematic review. MEDLINE via PubMed, ISI Web of Science and the Cochrane Database of Systematic Reviews were searched for eligible studies (2002-2016). The prevalence of brain death in adult patients resuscitated from cardiac arrest and the rate of organ donation among brain dead patients were summarised using a random effect model with double-arcsine transformation. The quality of evidence (QOE) was evaluated according to the GRADE guidelines. Results 26 studies [16 on conventional cardiopulmonary resuscitation (c-CPR), 10 on extracorporeal CPR (e-CPR)] included a total of 23,388 patients, 1830 of whom developed brain death at a mean time of 3.2 ± 0.4 days after recovery of circulation. The overall prevalence of brain death among patients who died before hospital discharge was 12.6 [10.2-15.2] %. Prevalence was significantly higher in e-CPR vs. c-CPR patients (27.9 [19.7-36.6] vs. 8.3 [6.5-10.4] %; p < 0.0001). The overall rate of organ donation among brain dead patients was 41.8 [20.2-51.0] % (9/26 studies, 1264 patients; range 0-100 %). The QOE was very low for both outcomes. Conclusions In patients with hypoxic-ischaemic brain injury following CPR, more than 10 % of deaths were due to brain death. More than 40 % of brain-dead patients could donate organs. Patients who are unconscious after resuscitation from cardiac arrest, especially when resuscitated using e-CPR, should be carefully screened for signs of brain death., Author(s): Claudio Sandroni [sup.1], Sonia D'Arrigo [sup.1], Clifton W. Callaway [sup.2], Alain Cariou [sup.3], Irina Dragancea [sup.4], Fabio Silvio Taccone [sup.5], Massimo Antonelli [sup.1] Author Affiliations: (1) grid.8142.f, 0000000109413192, Department [...]

Published
2016
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48. 2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group

Author

Wyckoff, Myra H., primary, Singletary, Eunice M., additional, Soar, Jasmeet, additional, Olasveengen, Theresa M., additional, Greif, Robert, additional, Liley, Helen G., additional, Zideman, David, additional, Bhanji, Farhan, additional, Andersen, Lars W., additional, Avis, Suzanne R., additional, Aziz, Khalid, additional, Bendall, Jason C., additional, Berry, David C., additional, Borra, Vere, additional, Böttiger, Bernd W., additional, Bradley, Richard, additional, Bray, Janet E., additional, Breckwoldt, Jan, additional, Carlson, Jestin N., additional, Cassan, Pascal, additional, Castrén, Maaret, additional, Chang, Wei-Tien, additional, Charlton, Nathan P., additional, Cheng, Adam, additional, Chung, Sung Phil, additional, Considine, Julie, additional, Costa-Nobre, Daniela T., additional, Couper, Keith, additional, Dainty, Katie N., additional, Davis, Peter G., additional, de Almeida, Maria Fernanda, additional, de Caen, Allan R., additional, de Paiva, Edison F., additional, Deakin, Charles D., additional, Djärv, Therese, additional, Douma, Matthew J., additional, Drennan, Ian R., additional, Duff, Jonathan P., additional, Eastwood, Kathryn J., additional, El-Naggar, Walid, additional, Epstein, Jonathan L., additional, Escalante, Raffo, additional, Fabres, Jorge G., additional, Fawke, Joe, additional, Finn, Judith C., additional, Foglia, Elizabeth E., additional, Folke, Fredrik, additional, Freeman, Karoline, additional, Gilfoyle, Elaine, additional, Goolsby, Craig A., additional, Grove, Amy, additional, Guinsburg, Ruth, additional, Hatanaka, Tetsuo, additional, Hazinski, Mary Fran, additional, Heriot, George S., additional, Hirsch, Karen G., additional, Holmberg, Mathias J., additional, Hosono, Shigeharu, additional, Hsieh, Ming-Ju, additional, Hung, Kevin K.C., additional, Hsu, Cindy H., additional, Ikeyama, Takanari, additional, Isayama, Tetsuya, additional, Kapadia, Vishal S., additional, Kawakami, Mandira Daripa, additional, Kim, Han-Suk, additional, Kloeck, David A., additional, Kudenchuk, Peter J., additional, Lagina, Anthony T., additional, Lauridsen, Kasper G., additional, Lavonas, Eric J., additional, Lockey, Andrew S., additional, Malta Hansen, Carolina, additional, Markenson, David, additional, Matsuyama, Tasuku, additional, McKinlay, Christopher J.D., additional, Mehrabian, Amin, additional, Merchant, Raina M., additional, Meyran, Daniel, additional, Morley, Peter T., additional, Morrison, Laurie J., additional, Nation, Kevin J., additional, Nemeth, Michael, additional, Neumar, Robert W., additional, Nicholson, Tonia, additional, Niermeyer, Susan, additional, Nikolaou, Nikolaos, additional, Nishiyama, Chika, additional, O’Neil, Brian J., additional, Orkin, Aaron M., additional, Osemeke, Osokogu, additional, Parr, Michael J., additional, Patocka, Catherine, additional, Pellegrino, Jeffrey L., additional, Perkins, Gavin D., additional, Perlman, Jeffrey M., additional, Rabi, Yacov, additional, Reynolds, Joshua C., additional, Ristagno, Giuseppe, additional, Roehr, Charles C., additional, Sakamoto, Tetsuya, additional, Sandroni, Claudio, additional, Sawyer, Taylor, additional, Schmölzer, Georg M., additional, Schnaubelt, Sebastian, additional, Semeraro, Federico, additional, Skrifvars, Markus B., additional, Smith, Christopher M., additional, Smyth, Michael A., additional, Soll, Roger F., additional, Sugiura, Takahiro, additional, Taylor-Phillips, Sian, additional, Trevisanuto, Daniele, additional, Vaillancourt, Christian, additional, Wang, Tzong-Luen, additional, Weiner, Gary M., additional, Welsford, Michelle, additional, Wigginton, Jane, additional, Wyllie, Jonathan P., additional, Yeung, Joyce, additional, Nolan, Jerry P., additional, Berg, Katherine M., additional, Abelairas-Gómez, Cristian, additional, Barcala-Furelos, Roberto, additional, Beerman, Stephen B., additional, Bierens, Joost, additional, Cacciola, Sofia, additional, Cellini, Jacqueline, additional, Claesson, Andreas, additional, Court, Rachael, additional, D’Arrigo, Sonia, additional, De Brier, Niels, additional, Dunne, Cody L., additional, Elsenga, Hylmar E., additional, Johnson, Samantha, additional, Kleven, Gunn, additional, Maconochie, Ian, additional, Mecrow, Tom, additional, Morgan, Patrick, additional, Otto, Quentin, additional, Palmieri, Tina L., additional, Parnia, Sam, additional, Pawar, Rahul, additional, Pereira, João, additional, Rudd, Sarah, additional, Scapigliati, Andrea, additional, Schmidt, Andrew, additional, Seesink, Jeroen, additional, Sempsrott, Justin R., additional, Szpilman, David, additional, Warner, David S., additional, Webber, Jonathon B., additional, and West, Rebecca L, additional

Published
2022
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49. sj-pdf-1-jva-10.1177_11297298221122092 – Supplemental material for A new pressure-based device for tip navigation and tip location during central venous catheterization: A prospective clinical study on a cohort of 136 adult patients

Author

D’Arrigo, Sonia, Emoli, Alessandro, Marche, Bruno, and Pittiruti, Mauro

Subjects
Cardiology
Abstract

Supplemental material, sj-pdf-1-jva-10.1177_11297298221122092 for A new pressure-based device for tip navigation and tip location during central venous catheterization: A prospective clinical study on a cohort of 136 adult patients by Sonia D’Arrigo, Alessandro Emoli, Bruno Marche and Mauro Pittiruti in The Journal of Vascular Access

Published
2022
Full Text
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50. Prediction of good neurological outcome in comatose survivors of cardiac arrest: a systematic review

Author

Claudio Sandroni, Arrigo, Sonia D., Cacciola, Sofia, Cornelia W, E. Hoedemaekers, Erik, Westhall, Marlijn J, A. Kamps, Fabio, S. Taccone, Daniele, Poole, Frederick J, A. Meijer, Massimo Antonelli, Karen, G. Hirsch, Jasmeet, Soar, Jerry, P. Nolan, and Tobias, Cronberg

Subjects
Settore MED/41 - ANESTESIOLOGIA, Cardiac arrest, Clinical examination, Coma, Computed tomography, Diffusion magnetic resonance imaging, Electroencephalogram, Neuron specific enolase, Prognosis, Somatosensory evoked potentials
Published
2022

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