126 results on '"D'Alterio C"'
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2. Safety and efficacy of intraperitoneal drain placement after emergency colorectal surgery: An international, prospective cohort study
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Sgro, A, Blanco-Colino, R, Ahmed, W, Brindl, N, Gujjuri, R, Lapolla, P, Mills, E, Perez-Ajates, S, Soares, A, Varghese, C, Xu, W, Mclean, K, Chapman, S, Espin-Basany, E, Glasbey, J, Mihaljevic, A, Nepogodiev, D, Pata, F, Pellino, G, Pockney, P, Dudi-Venkata, N, Egoroff, N, Ludbrook, I, Raubenheimer, K, Richards, T, Delibegovic, S, Salibasic, M, Amjad, T, Dorr-Harim, C, Gedeon, N, Gsenger, J, Tachezy, M, Bini, S, Gallo, G, Gori, A, Picciariello, A, Podda, M, Riboni, C, Machatschek, M, Nguyen, A, Jakubauskas, M, Kryzauskas, M, Poskus, T, Kuiper, S, Wang, J, Wells, C, Bissett, I, Augestad, K, Steinholt, I, Vieira, B, Juloski, J, Anabitarte Bautista, O, Kasmy El Kasmy, Y, Martin-Borregon, P, Ossola Revilla, M, Van Straten, S, Aktas, M, Baki, B, Akhbari, M, Baker, D, Bhatia, S, Brown, S, Cambridge, W, Kamarajah, S, Khaw, R, Kouli, O, Murray, V, Trout, I, Yasin, I, Wong, J, Reyhani, H, Wong, K, Pancharatnam, R, Chia, W, Walmsley, A, Hassane, A, Saeed, D, Wang, B, Walters, B, Nowinka, Z, Alsaif, A, Mirza, M, Foster, K, Luu, J, Kakodkar, P, Hughes, J, Yogarajah, T, Antypas, A, Rahman, A, Bradbury, M, Mclarnon, M, Nagi, S, Riad, A, Erotocritou, M, Kyriacou, H, Kaminskaite, V, Alfadhel, S, Fatimah Hussain, Q, Handa, A, Massy-Westropp, C, Custovic, S, Dimov, R, Mughal, H, Slavchev, M, Ivanov, T, Gouvas, N, Hegazi, A, Kocian, P, Kjaer, M, Mark-Christensen, A, Papakonstantinou, D, Machairas, N, Triantafyllou, T, Garoufalia, Z, Korkolis, D, Castaldi, A, Giaccari, S, Spolverato, G, Pagano, G, Milone, M, Turri, G, Colombo, F, Cucinotta, E, Poillucci, G, Perra, T, Tutino, R, Belia, F, Coletta, D, Belli, A, Rega, D, Cianci, P, Pirozzolo, G, Di Lena, M, Perrone, F, Giani, A, Lovisetto, F, Grassia, M, Pipitone Federico, N, Ferrara, F, Biancafarina, A, Tamini, N, Sinibaldi, G, Tuminello, F, Galleano, R, Sasia, D, Bragaglia, L, de Manzoni Garberini, A, Pesce, A, Cassaro, F, Venturelli, P, Canu, G, Esposito, G, Campanelli, M, Cardia, R, Ricciardiello, M, Sagnotta, A, Canonico, G, De Marco, G, Cappiello, A, Pinotti, E, Carlei, F, Lisi, G, Bagaglini, G, Farrugia, M, Meima - van Praag, E, Monteiro, C, Pereira, M, Botelho, P, Quigley, A, O'Neill, A, Gaule, L, Crone, L, Arnold, A, Grama, F, Beuca, A, Tulina, I, Litvin, A, Panyko, A, Ossola, M, Trujillo Diaz, J, Marin Santos, J, Alonso Batanero, E, Gortazar de las Casas, S, Soldevila Verdeguer, C, Colas-Ruiz, E, Talal El-Abur, I, Garcia Dominguez, M, Delorme, M, Sauvain, M, Ozmen, B, Ozkan, B, Calikoglu, F, Kural, S, Zafer, F, Kaya, Y, Yalcinkaya, A, Kargici, K, Tepe, M, Tatar, O, Kabadayi, E, Yildirim, A, Hurmuzlu, D, Korkmaz, K, Sharma, P, Troller, R, Hagan, N, Mooney, J, Light, A, Tansey, M, Bhojwani, D, Mcging, R, Mallon, A, Fadel, M, Spilsbury, C, James, R, O'Brien, S, Isaac, A, Balasubramanya, S, Sadik, H, Gala, T, Chen, J, Turner, B, Goh, E, Hassan, K, Karam, M, Mason, P, Tzoumas, N, Noton, T, Seehra, J, Ahmed, N, Motiwale, R, Tanna, V, Argyriou, A, Bylapudi, S, Grace, N, Latif, S, Hounat, A, Kiam, J, Zaidi, M, Elsamani, K, Hughes, C, Suresh, A, Sinan, L, El-Dalil, D, Khoo, E, Salim, E, Stark, D, Minhas, N, Fowler, G, Rees, E, Giudiceandrea, I, Bardon, A, Jayawardena, P, Dieseru, N, Murphy, A, Yates, C, Ziolkowska, K, Rafie, A, Khoda, F, Okocha, M, Ashdown, T, Vitish-Sharma, P, Gilliland, J, Toh, S, Jones, K, Devine, A, Berry, A, Mcdonnell, S, Olivier, J, Richardson, G, Lim, H, Slim, N, Elsayeh, K, Sammour, T, Sarpanov, A, Belev, N, Dimitrov, D, Dusek, T, Ntomi, V, Sotiropoulos, G, Theodorou, D, Nikiteas, N, Balalis, D, Antropoli, C, Altomare, D, Luglio, G, De Palma, G, Pedrazzani, C, Simonelli, L, Brozzetti, S, Porcu, A, Massani, M, Grazi, G, Izzo, F, Delrio, P, Restini, E, Chetta, G, Lantone, G, Ferrari, G, Lucchi, A, De Prizio, M, Caristo, G, Borghi, F, Petrucciani, N, Huscher, C, Cocorullo, G, Tonini, V, Medas, F, Sica, G, Cillara, N, Anastasi, A, Bianco, F, Giuliani, A, Carlini, M, Selvaggi, F, Sammarco, G, Ozolins, A, Malasonoks, A, Andrejevic, P, Tanis, P, van de Ven, A, Gerhards, M, Ribeiro da Silva, B, Silva, A, Lima, M, Kavanagh, D, Mccawley, N, Bintintan, V, Karamarkovic, A, Sanz Ortega, G, De Andres-Asenjo, B, Nevado Garcia, C, Garcia Florez, L, Segura-Sampedro, J, Blas Laina, J, Ponchietti, L, Buchwald, P, Gialamas, E, Ozben, V, Rencuzogullari, A, Gecim, I, Altinel, Y, Isik, O, Yoldas, T, Isik, A, Leventoglu, S, Erturk, M, Guner, A, Guler, S, Attaallah, W, Ugur, M, Ozbalci, G, Marzook, H, Eardley, N, Smolarek, S, Morgan, R, Roxburgh, C, Lala, A, Salama, Y, Singh, B, Khanna, A, Evans, M, Shaikh, I, Maradi Thippeswamy, K, Appleton, B, Moug, S, Smith, I, Smart, N, Shah, P, Williams, G, Khera, G, Goede, A, Varcada, M, Parmar, C, Duff, S, Hargest, R, Marriott, P, Speake, D, Ben Sassi, A, Furfaro, B, Daudu, D, Golijanin, N, Yek, W, Capasso, G, Mansour, L, Niu, N, Seow, W, Hamidovic, A, Kulovic, E, Letic, E, Aljic, A, Helez, M, Banji-Kelan, A, Dimitrova, N, Kavradjieva, P, Ivanov, V, Jukaku, A, Hadzhiev, D, Gabarski, A, Karamanliev, M, Vladova, P, Iliev, S, Yotsov, T, Epsilonupsilonsigmataualphathetaiotaomicronupsilon, E, Vetsa, K, Stavrinidou, O, Papatheodorou, P, Liassides, T, Georgiou, T, Al Nassrallah, M, Altaf, R, Negametzyanov, M, Zagibova, D, Foltys, F, Stefanova, H, Paspala, A, Bompetsi, G, Sidiropoulos, T, Stamopoulos, P, Triantafyllou, A, Theodoropoulos, C, Kimpizi, A, Palyvou, T, Charalabopoulos, A, Syllaios, A, Schizas, D, Liatsou, E, Baili, E, Vagios, I, Tomara, N, Davakis, S, Palumbo, A, Foroni, F, Dibra, R, Papagni, V, Urbani, A, Rossin, E, Nezi, G, Romano, P, Amendola, A, Esposito, E, Manigrasso, M, Anoldo, P, Vertaldi, S, Gecchele, G, Sabrina, Z, Guerci, C, Cammarata, F, Lamperti, G, Zaffaroni, G, Benuzzi, L, Ferrario, L, Cigognini, M, Mazzeo, C, Badessi, G, Pintabona, G, Fassari, A, Mingoli, A, Cirillo, B, D'Alterio, C, Brachini, G, Tancredi, M, Zambon, M, Aulicino, M, Sapienza, P, Liberatore, P, Scanu, A, Feo, C, Iacomino, A, Pelizzo, P, Rossi, S, Vigna, S, Grossi, U, Grillo, V, Agnes, A, Schena, C, Marincola, G, Oddi, A, Perotti, B, Mario, V, Perri, P, Zazza, S, Aversano, A, Scala, D, Di Lauro, K, Leongito, M, Piccirillo, M, Patrone, R, Capuzzolo, S, Vignotto, C, Bao, Q, Giuseppe, C, Angarano, E, Marino, F, Pezzolla, F, Gigante, G, Magistro, C, Crippa, J, Maspero, M, Carnevali, P, Trapani, R, Zonta, S, Agostinelli, L, Vittori, L, Romeo, L, Doria, E, Farnesi, F, Danna, R, Andolfi, E, Pellicano', G, Angelini, M, Scricciolo, M, Zanframundo, C, Ciulli, C, Ripamonti, L, Cigagna, L, Oldani, M, Larcinese, A, Rossi, D, Picone, E, Crescentini, G, Marano, A, Migliore, M, Giuffrida, M, Palagi, S, Testa, V, Borrello, A, Lucarini, A, Garofalo, E, Canali, G, Orlandi, P, Nervegna, F, Marchegiani, F, Damoli, I, Licata, A, Trovato, C, Alicata, F, Sardo, F, Milazzo, M, Randisi, B, Dominici, D, Sartarelli, L, Zanni, M, Pisanu, A, Soddu, C, Delogu, D, Erdas, E, Campus, F, Cappellacci, F, Casti, F, Marcialis, J, Atzeni, J, Sensi, B, Franceschilli, M, Bellato, V, Cannavera, A, Putzu, G, di Mola, F, Picardi, B, Solinas, L, Loponte, M, Rossi del Monte, S, Di Martino, C, Linari, C, Spagni, G, Capezzuoli, L, Tirloni, L, Nelli, T, Caridi, A, Elter, C, Camassa, M, D'Amico, S, Bargellini, T, Incollingo, P, Montuori, M, Maffione, F, Romano, L, Valiyeva, S, Spoletini, D, Menegon Tasselli, F, Sciaudone, G, Selvaggi, L, Menna, M, De Paola, G, Fulginiti, S, Truskovs, A, Weiss, C, Saknitis, G, Rauscher, J, Larnovskis, J, Jeyarajan-Davidsson, M, Nitisa, D, Gille, N, Reiser, S, Roshan, M, Leseman, C, van Dalen, A, Top, C, Detering, R, Matos, C, Silva, C, Pinto, D, Mendes, J, Couto, J, Leite, M, Velez, C, Damasio Cotovio, M, Cinza, A, Pedroso de Lima, R, Boyle, E, Yang, H, Banerjee, I, Rahmat, S, Afzal, Z, Reid, C, Dumitrascu, F, Croyle, J, Gressmann, K, Cullen, N, Graham, A, Nasehi, A, Montano King, C, Martin, B, Stokell, C, Sanderson, N, Farnan, R, Jassim, S, Chan, B, Chua Vi Long, K, Kaka, N, Pandey, S, Neo, W, Chitul, A, Bezede, C, Cincilei, D, David, A, Blaga, M, Blaga, S, Fagarasan, V, Khetagurova, M, Rodimov, S, Kapustina, A, Mekhralyzade, A, Zabiyaka, M, Jankovic, U, Cuk, V, Hajska, M, Dubovsky, M, Hrosova, M, Ferancikova, N, Camarero Rodriguez, E, Laguna Alcantara, F, Adarraga, J, Jezieniecki, C, Ruiz Soriano, M, Gomez Sanz, T, Suarez, A, Sanchez Garcia, C, Cifrian Canales, I, Llosa Perez, J, Merayo, M, Urbieta, A, Gegundez Simon, A, Tone, J, Gazo Martinez, J, Vicario Bravo, M, Chavarrias, N, Gil Catalan, A, Oseira, A, Villalonga, B, Jeri, S, Perez Calvo, J, Nogues, A, Cros, B, Yanez, C, Utrilla Fornals, A, Roldon Golet, M, Colsa, P, Gimenez Maurel, T, Axmarker, T, Chevallay, M, Pham, T, Sel, E, Atar, C, Aba, M, Sarkin, M, Akkaya, Y, Durmaz, A, Gullu, H, Boga, A, Aktas, A, Bakar, B, Demirel, M, Hysejni, X, Taser, M, Guzel, O, Bozbiyik, O, Ozen, D, Olmez, M, Uyar, B, Gulcek, E, Kayacan, G, Atici, N, Gul, O, Altiner, S, Ibis, B, Altunsu, S, Banaz, T, Diler, C, Demirbas, I, Usta, M, Erkul, O, Orman, R, Salih, S, Utkan, N, Acil, C, Ozgur, E, Maddahali, M, Turhan, A, Eskici, A, Ular, B, Dogru, M, Ozturk, O, Arslan, E, Panahi Sharif, A, Dikmen, E, Ates, J, Bircan, R, Cavus, T, Sever, A, Balak, B, Duman, E, Altay, L, Emanet, O, Cullen, F, Tan, J, Nathan, A, Rottenberg, A, Williams, C, Mitrofan, C, Xu, D, Bawa, J, Morris, P, Gordon, D, Richmond, G, Hui, J, Ighomereho, O, Rocks, R, Mccabe, S, Fitzpatrick, A, Nicoletti, J, Auterson, L, Darrah, N, Soh, V, Ong, C, Utukuri, M, Gallagher, C, Stuart, L, Hipolito, M, Douglas, N, Ghazal, R, Parris, G, Catchpole, J, Bryden, M, Jamal, S, Karim, Z, Lyon-Dean, C, Rowley, G, Lee, K, Whitehurst, O, Mirza, A, Sheikh, F, Yousaf, H, Bilbao, J, Sinclair, R, Takar, S, Kressel, H, Chan, V, Schack, K, Osborne, R, Baldemor, S, Smyth, S, Gilmour, S, Ting, A, Bozonelou, I, Saunders, P, Qhaireel Anwar, Q, Tirimanna, R, Jauhari, S, Gardener, A, Walker, B, Wenban, C, Reddy, H, Conway-Jones, R, Loganathan, S, Clynch, A, James, C, Matey, E, Cameron, F, Roberts, W, Gicquel, A, Milliken, C, Forbes, J, Rubinchik, P, Azmi, A, Hawkes, C, Cornett, L, Adarkwah, P, Mcconville, R, O'Hara, S, Tijare, C, Parkes, J, Yao, L, Ahmad, R, Shafiq, U, Mhaisalkar, A, Gurung, A, de Stadler, K, Elias, S, Thomas, T, Madras, A, Jani, A, Daler, H, Tong, K, Sundaralingam, S, Szal, A, Khan, A, O'Sullivan, C, Baker, E, Joseph-Gubral, J, Hadley, E, Trivedi, R, Igwelaezoh, E, Barton, H, Allison, W, Hurst, W, Alam, F, Parkes, I, Jamshaid, M, Azizan, N, Burgher, T, Afzal, A, Eltilib, I, Zahid, M, Sadiq, O, Lloyd, A, Ho, R, Brazukas, A, Li, C, Kamdar, M, Mohamed Nazeer, M, Mighiu, A, Kim, D, Wilkins, L, Kuo, L, Rafe, T, Maduka, D, Cheema, H, Farag, K, Abdellatif, M, Nzewi, R, Kruczynska, A, Grasselli, H, Yousuff, M, Bassi, R, Mann, A, Chopra, J, Shaikh, M, D Sa, S, Tsimplis, V, Ghanchi, A, Skene, E, Asim, K, Zaheer, M, Chan, S, Dalton, H, Gibbons, K, Adderley, O, Chukwujindu, I, Jayasuriya, I, Sivanu, K, Borumand, M, Chick, G, Bridges, I, Tomlin, J, Mckenna, J, Nandra, N, Grieco, C, Quek, F, Mercer, R, Brankin-Frisby, T, Sattar, A, Aslam, A, Edelsten, E, Shafi, S, Kouli, T, Ford, V, Gurung, F, Fernandes, M, Deader, N, Ponniah, R, Jamieson, S, Davies, A, Taubwurcel, J, Aung, M, Desai, R, Begum, S, Jamadar, T, Kangatharan, A, Rzeszowski, B, Ho, C, Yap, S, Prendergast, M, Sethi, R, Duku, A, Lowe, C, Bray, J, Ghobrial, M, Nichita, V, Wagstaff, A, Rengasamy, E, Abu Hassan, F, Mahmood, H, Savill, N, Shah, S, Almeida, T, Edwards, A, Catchpole, B, Halford, Z, Carmichael, A, Alsusa, H, Boyd, M, Williams, J, Feyi-Waboso, J, Patel, M, Zeidan, Z, Bailey, E, Bapty, J, Brazkiewicz, M, Tremlett, A, Pringle, H, Mankal, S, Chung, W, Parry-Jones, E, Anderson, K, Mcforrester, A, Stanley, A, Hoather, A, Wise, H, Laid, I, Scriven, J, Braniste, A, Wilson, A, Le Blevec, L, Pakunwanich, N, Evans, N, Chong, H, White, C, Hunter, J, Haque, M, Vanalia, P, Murdoch, S, Choudhary, T, Mccann, A, Harun, A, Shah, H, Hunt, S, Shafiq, Y, Bickley-Morris, E, Emms, L, Dare, M, Akula, Y, Deliyannis, E, Mayes, F, Ellacott, M, Zagorac, Z, Farren, A, Manning, C, Hughed, C, Stewart, E, Lim, K, Chohan, N, Thaker, A, Thompson, B, Ahari, D, Burdekin, E, Okwu, U, Akintunde, A, Lhaf, F, Douthwaite, J, Govindan, R, Leelamanthep, S, Gull, E, Wright, F, Dundas, L, Mackdermott, N, Burchi-Khairy, T, Campbell, I, Walsh, J, Yeo, J, Meehan, S, Banerjee, D, Fu, M, Kawka, M, Ali, T, Hussain, Z, Thomas, C, Ahmad, H, Moroney, J, Yick, C, Risquet, R, Ntuiabane, D, Shimato, M, Khan, M, Ilangovan, S, Vaselli, N, Smithers, R, Uhanowita Marage, R, Valnarov-Boulter, A, Kayran, J, Banerjee, M, Parekh-Hill, N, Hooper, A, Bowen, J, Jagdish, R, Mcquoid, C, Khan, N, O Hare, R, Jeffery, S, Zahid, A, Elsworth, C, Walter, L, Dhillon, S, Rao, S, Anthony, A, Ashaye, A, Phillips, N, Faderani, R, Pengelly, S, Choi, S, Kwak, S, Lau, Y, Bagheri, K, Ong, D, Kerr, E, Falconer, K, Clancy, N, Douglas, S, Zhang, Y, Greenfield, F, Mutanga, I, Mcalinden, J, Willis, L, Adefolaju, A, Agarwal, H, Barter, R, Harris, G, Spencer, G, Lee, M, V Vadiveloo, T, Herbert, G, Patel, R, Shah, M, El Falaha, S, Wong, C, Soare, C, Akram, J, Bozhkova, L, Ma, Y, Vo, U, Tan, H, Leto, L, Kamal, M, Hadzhieva, E, Krastev, P, Tonchev, P, Kokkinos, G, Pozotou, I, Sabbagh, D, Votava, J, St, F, Koliakos, N, Tsaparas, P, Zografos, G, Mantas, D, Tsourouflis, G, Fradelos, E, Trigiante, G, Labellarte, G, Resta, G, Capelli, G, D'Amore, A, Verlingieri, V, Campagnaro, T, Maffioli, A, Viscosi, F, De Lucia, C, Meneghini, S, Fancellu, A, Colella, M, Biondi, A, De Peppo, V, Pace, U, Albino, V, Gattulli, D, Piangerelli, A, Kalivaci, D, Sisto, G, Mazzola, M, Caneparo, A, Lunghi, E, Nespoli, L, Angrisani, M, Langone, A, Gelarda, E, Virgilio, E, Angelini, E, Fornasier, C, Asero, S, Filippone, E, Frongia, F, Calo, P, Panaccio, P, Ipponi, P, Gili, S, Braccio, B, Tiesi, V, Stolcers, K, Kokaine, L, Novikovs, V, Capel, L, Bastiaenen, V, Heijmans, H, Henriques, S, Gan, S, Ramanayake, H, Nolan, M, Temperley, H, Ciofic, E, Pop, B, Kurtenkov, M, Jovanovic, M, Vician, M, Egea Arias, P, Beltran de Heredia, J, Labalde Martinez, M, De Santiago Alvarez, I, Alvarez-Gallego, M, Rodriguez Artigas, J, Dwidar, O, Korkmaz, H, Eray, I, Meric, S, Aydin, R, Cetin, B, Karaca, B, Kuyumcu, O, Yuksel, E, Uprak, T, Karabulut, K, Kavukcu, E, Mansor, A, Hackett, R, Zammit-Maempel, M, Sabaratnam, R, Maan, A, Ferarrio, I, Dixon, L, Halai, H, Sethi, S, Nelson, L, Grassam-rowe, A, Krishnan, E, Deeny, D, Mckeever, M, George Pandeth, A, Dhavala, P, Sreenivasan, S, Sundaram Venkatesan, G, Zhu, L, Atiyah, Z, Gregory, J, Morey, T, Seymour, Z, Holdsworth, L, Abdelmahmoud, S, Bourhill, J, Bisheet, G, Shaw, J, Kulkarni, K, Kumarakulasingam, P, Pillay, S, Al-Habsi, R, Kungwengwe, G, Richards, J, Davoudi, K, Ibrahim, B, Tailor, B, Zayed, M, Chen, F, Bailey, S, Sheefat, S, Nawaz, G, Pawar, R, Marsh, S, Sam, Z, Roy Bentley, S, Simpson, C, Lim, Y, Ooi, R, Toh, W, Mannion, P, Lovett, A, Kincius, A, Hussein, S, Kirby, E, Beckett, R, Salmon, J, Glynn, T, Choo, S, Lyons, S, Browne, D, Ravindran, W, Ahmad, S, Zhu, X, Mcnulty, J, Mccarthy, L, Ng, J, Karmally, Z, Mcteir, K, Hanna, M, Tan, E, Namdeo, S, Schembri, R, Pusey, E, Sgro A., Blanco-Colino R., Ahmed W. U. R., Brindl N., Gujjuri R. R., Lapolla P., Mills E. C., Perez-Ajates S., Soares A. S., Varghese C., Xu W., McLean K. A., Chapman S. J., Espin-Basany E., Glasbey J. C., Mihaljevic A., Nepogodiev D., Pata F., Pellino G., Pockney P., Dudi-Venkata N. N., Egoroff N., Ludbrook I., Raubenheimer K., Richards T., Delibegovic S., Salibasic M., Amjad T., Dorr-Harim C., Gedeon N., Gsenger J., Tachezy M., Bini S., Gallo G., Gori A., Picciariello A., Podda M., Riboni C., Machatschek M. J., Nguyen A., Jakubauskas M., Kryzauskas M., Poskus T., Kuiper S. Z., Wang J., Wells C. I., Bissett I. P., Augestad K. M., Steinholt I., Vieira B. N., Juloski J., Anabitarte Bautista O., Kasmy El Kasmy Y., Martin-Borregon P., Ossola Revilla M., Van Straten S., Aktas M. K., Baki B. E., Akhbari M., Baker D., Bhatia S., Brown S., Cambridge W., Kamarajah S. K., Khaw R. A., Kouli O., Murray V., Trout I., Yasin I., Wong J. Y., Reyhani H., Wong K. H. F., Pancharatnam R., Chia W. L., Walmsley A., Hassane A., Saeed D., Wang B., Walters B., Nowinka Z., Alsaif A., Mirza M., Foster K., Luu J., Kakodkar P., Hughes J. T., Yogarajah T., Antypas A., Rahman A., Bradbury M., McLarnon M., Nagi S., Riad A. M., Erotocritou M., Kyriacou H., Kaminskaite V., Alfadhel S., Fatimah Hussain Q., Handa A., Massy-Westropp C., Custovic S., Dimov R., Mughal H., Slavchev M., Ivanov T., Gouvas N., Hegazi A., Kocian P., Kjaer M. D., Mark-Christensen A., Papakonstantinou D., Machairas N., Triantafyllou T., Garoufalia Z., Korkolis D., Castaldi A., Giaccari S., Spolverato G., Pagano G., Milone M., Turri G., Colombo F., Cucinotta E., Poillucci G., Perra T., Tutino R., Belia F., Coletta D., Belli A., Rega D., Cianci P., Pirozzolo G., Di Lena M., Perrone F., Giani A., Lovisetto F., Grassia M., Pipitone Federico N. S., Ferrara F., Biancafarina A., Tamini N., Sinibaldi G., Tuminello F., Galleano R., Sasia D., Bragaglia L., de Manzoni Garberini A., Pesce A., Cassaro F., Venturelli P., Canu G. 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B., Zaffaroni G., Benuzzi L., Ferrario L., Cigognini M., Mazzeo C., Badessi G., Pintabona G., Fassari A., Mingoli A., Cirillo B., D'Alterio C., Brachini G., Tancredi M., Zambon M., Aulicino M., Sapienza P., Liberatore P., Scanu A. M., Feo C. F., Iacomino A., Pelizzo P., Rossi S., Vigna S. A., Grossi U., Grillo V., Agnes A., Schena C. A., Marincola G., Oddi A., Perotti B., Mario V., Perri P., Zazza S., Aversano A., Scala D., Di Lauro K., Leongito M., Piccirillo M., Patrone R., Capuzzolo S., Vignotto C., Bao Q. R., Giuseppe C., Angarano E., Marino F., Pezzolla F., Gigante G., Magistro C., Crippa J., Maspero M., Carnevali P., Trapani R., Zonta S., Agostinelli L., Vittori L., Romeo L., Doria E., Farnesi F., Danna R., Andolfi E., Pellicano' G. A., Angelini M., Scricciolo M., Zanframundo C., Ciulli C., Ripamonti L., Cigagna L., Oldani M., Larcinese A., Rossi D., Picone E., Crescentini G., Marano A., Migliore M., Giuffrida M. C., Palagi S., Testa V., Borrello A., Lucarini A., Garofalo E., Canali G., Orlandi P., Nervegna F., Marchegiani F., Damoli I., Licata A., Trovato C., Alicata F., Sardo F., Milazzo M., Randisi B., Dominici D. M., Sartarelli L., Zanni M., Pisanu A., Soddu C., Delogu D., Erdas E., Campus F., Cappellacci F., Casti F., Marcialis J., Atzeni J., Podda M. G., Sensi B., Franceschilli M., Bellato V., Cannavera A., Putzu G., di Mola F. F., Picardi B., Solinas L., Loponte M., Rossi del Monte S., Di Martino C., Linari C., Spagni G., Capezzuoli L., Tirloni L., Nelli T., Caridi A., Elter C., Camassa M., D'Amico S., Bargellini T., Incollingo P., Montuori M., Maffione F., Romano L., Valiyeva S., Spoletini D., Menegon Tasselli F., Sciaudone G., Selvaggi L., Menna M. P., De Paola G., Fulginiti S., Truskovs A., Weiss C., Saknitis G., Rauscher J. T. R., Larnovskis J., Jeyarajan-Davidsson M., Nitisa D., Gille N., Reiser S. C., Roshan M. H. K., Leseman C., Chen J., van Dalen A. S., Top C., Detering R., Matos C., Silva C., Pinto D., Mendes J., Couto J., Leite M., Velez C., Damasio Cotovio M., Cinza A. M., Pedroso de Lima R., Boyle E., Yang H. W., Banerjee I., Rahmat S., Afzal Z., Reid C., Dumitrascu F., Croyle J. A., Gressmann K., Cullen N., Graham A., Nasehi A., Montano King C., Martin B., Stokell C., Sanderson N., Farnan R., Jassim S., Chan B., Chua Vi Long K., Kaka N., Pandey S., Neo W. X., Chitul A., Bezede C., Cincilei D., David A., Blaga M., Blaga S. N., Fagarasan V., Khetagurova M., Rodimov S., Kapustina A., Mekhralyzade A., Zabiyaka M., Jankovic U., Cuk V., Hajska M., Dubovsky M., Hrosova M., Ferancikova N., Camarero Rodriguez E., Laguna Alcantara F., Adarraga J., Jezieniecki C., Ruiz Soriano M., Gomez Sanz T., Suarez A., Sanchez Garcia C., Cifrian Canales I., Llosa Perez J., Merayo M., Urbieta A., Gegundez Simon A., Tone J. F., Gazo Martinez J., Vicario Bravo M., Chavarrias N., Gil Catalan A., Oseira A., Villalonga B., Jeri S., Perez Calvo J., Nogues A., Cros B., Yanez C., Utrilla Fornals A., Roldon Golet M., Colsa P., Gimenez Maurel T., Axmarker T., Chevallay M., Pham T. V., Sel E. K., Atar C., Aba M., Sarkin M., Akkaya Y. M., Durmaz A. G., Gullu H. F., Boga A., Aktas A., Bakar B., Demirel M. T., Hysejni X., Taser M., Guzel O. R., Bozbiyik O., Ozen D., Olmez M., Uyar B., Gulcek E., Kayacan G. S., Atici N., Gul O. F., Altiner S., Ibis B., Altunsu S., Banaz T., Diler C., Demirbas I., Usta M. A., Erkul O., Orman R., Salih S., Utkan N. Z., Acil C., Ozgur E., Maddahali M., Turhan A. B., Eskici A. B., Ular B., Dogru M., Ozturk O. U., Arslan E. R., Panahi Sharif A., Dikmen E., Ates J., Bircan R., Cavus T., Sever A. E., Balak B., Duman E., Altay L., Emanet O., Cullen F., Tan J. Y., Nathan A., Rottenberg A., Williams C. Y., Mitrofan C. G., Xu D., Bawa J. H., Morris P., Gordon D., Richmond G., Hui J. C., Ighomereho O., Rocks R., McCabe S., Fitzpatrick A., Nicoletti J., Auterson L., Darrah N., Soh V. W. Y., Ong C. S., Utukuri M., Gallagher C., Stuart L. M., Hipolito M., Douglas N., Ghazal R., Parris G., Catchpole J., Bryden M., Jamal S., Karim Z., Lyon-Dean C., Rowley G., Lee K. S., Whitehurst O., Mirza A., Sheikh F., Yousaf H., Bilbao J., Sinclair R., Takar S., Kressel H., Chan V., Schack K., Osborne R., Baldemor S., Smyth S., Gilmour S., Ting A., Bozonelou I., Saunders P., Qhaireel Anwar Q. A., Tirimanna R., Jauhari S., Gardener A., Walker B., Wenban C., Reddy H., Conway-Jones R., Loganathan S., Clynch A., James C., Matey E., Cameron F., Roberts W., Gicquel A., Milliken C., Forbes J., Rubinchik P., Azmi A., Hawkes C., Cornett L., Adarkwah P., McConville R., O'Hara S., Tijare C., Parkes J., Yao L., Ahmad R., Shafiq U., Mhaisalkar A., Gurung A., de Stadler K., Elias S., Thomas T., Madras A., Jani A., Daler H. K., Tong K. S., Sundaralingam S. S., Szal A., Khan A., O'Sullivan C., Baker E., Joseph-Gubral J., Hadley E., Trivedi R., Igwelaezoh E., Barton H., Allison W., Hurst W., Alam F., Parkes I., Jamshaid M., Azizan N., Burgher T., Afzal A., Eltilib I., Zahid M., Sadiq O., Lloyd A., Ho R., Brazukas A., Li C. H., Kamdar M., Mohamed Nazeer M. N., Mighiu A., Kim D., Wilkins L., Kuo L., Rafe T., Maduka D., Cheema H., Farag K., Abdellatif M., Nzewi R., Kruczynska A., Grasselli H., Yousuff M., Bassi R., Mann A. K., Chopra J., Shaikh M., D Sa S., Tsimplis V., Ghanchi A., Skene E., Asim K., Zaheer M., Chan S., Dalton H., Gibbons K., Adderley O., Chukwujindu I., Jayasuriya I., Sivanu K., Borumand M., Chick G., Bridges I., Tomlin J., McKenna J., Nandra N., Grieco C., Quek F. F., Mercer R., Brankin-Frisby T., Sattar A., Aslam A., Edelsten E., Shafi S., Kouli T., Ford V., Gurung F., Fernandes M., Deader N., Ponniah R., Jamieson S., Davies A., Taubwurcel J., Aung M. T., Desai R., Begum S., Jamadar T., Kangatharan A., Rzeszowski B., Ho C., Yap S. H. K., Prendergast M., Sethi R., Duku A., Lowe C., Bray J., Ghobrial M., Nichita V., Wagstaff A., Rengasamy E., Abu Hassan F., Mahmood H., Savill N., Shah S., Almeida T., Edwards A., Catchpole B., Halford Z., Carmichael A., Alsusa H., Boyd M., Williams J., Feyi-Waboso J., Patel M., Zeidan Z., Bailey E., Bapty J., Brazkiewicz M., Tremlett A., Pringle H., Mankal S., Chung W., Parry-Jones E., Anderson K., Mcforrester A., Stanley A., Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H. L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E. G., Lim K. H., Chohan N., Thaker A., Thompson B., Ahari D., Burdekin E., Okwu U., Akintunde A., Lhaf F., Douthwaite J., Govindan R., Leelamanthep S., Gull E., Wright F., Dundas L., Mackdermott N., Burchi-Khairy T., Campbell I., Walsh J., Yeo J. Y., Meehan S., Banerjee D., Fu M., Kawka M., Ali T., Hussain Z., Thomas C., Ahmad H., Moroney J., Yick C., Risquet R., Ntuiabane D., Shimato M., Khan M., Ilangovan S., Vaselli N. M., Smithers R., Uhanowita Marage R., Valnarov-Boulter A., Kayran J., Banerjee M., Parekh-Hill N., Hooper A., Bowen J., Jagdish R., Mcquoid C., Khan N., O Hare R., Jeffery S., Zahid A., Elsworth C., Walter L., Dhillon S., Rao S., Anthony A., Ashaye A., Phillips N., Faderani R., Pengelly S., Choi S., Kwak S. Y., Lau Y. H. L., Bagheri K., Ong D. Y. C., Kerr E., Falconer K., Clancy N., Douglas S., Zhang Y., Greenfield F., Mutanga I., McAlinden J., Willis L., Adefolaju A., Agarwal H., Barter R., Harris G., Spencer G., Lee M. W., V Vadiveloo T., Herbert G., Patel R., Shah M., El Falaha S., Wong C., Soare C., Akram J., Bozhkova L., Ma Y., Vo U. G., Tan H. W. N., Leto L., Kamal M. A., Hadzhieva E., Krastev P., Tonchev P., Kokkinos G., Pozotou I., Sabbagh D., Votava J., St F., Koliakos N., Tsaparas P., Zografos G., Mantas D., Tsourouflis G., Fradelos E., Trigiante G., Labellarte G., Resta G., Capelli G., D'Amore A., Verlingieri V., Campagnaro T., Maffioli A., Viscosi F., De Lucia C., Meneghini S., Fancellu A., Colella M., Biondi A., De Peppo V., Pace U., Albino V., Gattulli D., Piangerelli A., Kalivaci D., Sisto G., Mazzola M., Caneparo A., Lunghi E. G., Nespoli L. C., Angrisani M., Langone A., Gelarda E., Virgilio E., Angelini E., Fornasier C., Asero S., Filippone E., Frongia F., Calo P. G., Panaccio P., Ipponi P., Gili S., Braccio B., Tiesi V., Stolcers K., Kokaine L., Novikovs V., Capel L., Bastiaenen V., Heijmans H., Henriques S., Gan S. Z., Ramanayake H., Nolan M., Temperley H., Ciofic E., Pop B. A., Kurtenkov M., Jovanovic M., Vician M., Egea Arias P., Beltran de Heredia J., Labalde Martinez M., De Santiago Alvarez I., Alvarez-Gallego M., Rodriguez Artigas J. M., Dwidar O., Korkmaz H. K., Eray I. C., Meric S., Aydin R., Cetin B., Karaca B. E., Kuyumcu O. F., Yuksel E., Uprak T. K., Karabulut K., Kavukcu E., Mansor A., Hackett R., Zammit-Maempel M., Sabaratnam R., Maan A., Ferarrio I., Dixon L., Halai H., Sethi S., Nelson L., Grassam-rowe A., Krishnan E., Deeny D., McKeever M., George Pandeth A., Dhavala P., Sreenivasan S., Sundaram Venkatesan G., Zhu L., Atiyah Z., Gregory J., Morey T., Seymour Z., Holdsworth L., Abdelmahmoud S., Bourhill J., Bisheet G., Shaw J., Kulkarni K., Kumarakulasingam P., Pillay S., Al-Habsi R., Kungwengwe G., Richards J., Davoudi K., Ibrahim B., Tailor B., Zayed M., Chen F., Bailey S., Sheefat S., Nawaz G., Pawar R., Marsh S., Sam Z. H., Roy Bentley S., Simpson C., Hughes J., Lim Y., Ooi R., Toh W. H., Mannion P., Lovett A., Kincius A., Hussein S., Kirby E., Beckett R. G., Salmon J., Glynn T., Choo S. Y., Lyons S., Browne D., Ravindran W., Ahmad S., Zhu X., McNulty J., McCarthy L., Ng J., Karmally Z., McTeir K., Hanna M., Tan E., Namdeo S., Schembri R., Pusey E., Sgro, A, Blanco-Colino, R, Ahmed, W, Brindl, N, Gujjuri, R, Lapolla, P, Mills, E, Perez-Ajates, S, Soares, A, Varghese, C, Xu, W, Mclean, K, Chapman, S, Espin-Basany, E, Glasbey, J, Mihaljevic, A, Nepogodiev, D, Pata, F, Pellino, G, Pockney, P, Dudi-Venkata, N, Egoroff, N, Ludbrook, I, Raubenheimer, K, Richards, T, Delibegovic, S, Salibasic, M, Amjad, T, Dorr-Harim, C, Gedeon, N, Gsenger, J, Tachezy, M, Bini, S, Gallo, G, Gori, A, Picciariello, A, Podda, M, Riboni, C, Machatschek, M, Nguyen, A, Jakubauskas, M, Kryzauskas, M, Poskus, T, Kuiper, S, Wang, J, Wells, C, Bissett, I, Augestad, K, Steinholt, I, Vieira, B, Juloski, J, Anabitarte Bautista, O, Kasmy El Kasmy, Y, Martin-Borregon, P, Ossola Revilla, M, Van Straten, S, Aktas, M, Baki, B, Akhbari, M, Baker, D, Bhatia, S, Brown, S, Cambridge, W, Kamarajah, S, Khaw, R, Kouli, O, Murray, V, Trout, I, Yasin, I, Wong, J, Reyhani, H, Wong, K, Pancharatnam, R, Chia, W, Walmsley, A, Hassane, A, Saeed, D, Wang, B, Walters, B, Nowinka, Z, Alsaif, A, Mirza, M, Foster, K, Luu, J, Kakodkar, P, Hughes, J, Yogarajah, T, Antypas, A, Rahman, A, Bradbury, M, Mclarnon, M, Nagi, S, Riad, A, Erotocritou, M, Kyriacou, H, Kaminskaite, V, Alfadhel, S, Fatimah Hussain, Q, Handa, A, Massy-Westropp, C, Custovic, S, Dimov, R, Mughal, H, Slavchev, M, Ivanov, T, Gouvas, N, Hegazi, A, Kocian, P, Kjaer, M, Mark-Christensen, A, Papakonstantinou, D, Machairas, N, Triantafyllou, T, Garoufalia, Z, Korkolis, D, Castaldi, A, Giaccari, S, Spolverato, G, Pagano, G, Milone, M, Turri, G, Colombo, F, Cucinotta, E, Poillucci, G, Perra, T, Tutino, R, Belia, F, Coletta, D, Belli, A, Rega, D, Cianci, P, Pirozzolo, G, Di Lena, M, Perrone, F, Giani, A, Lovisetto, F, Grassia, M, Pipitone Federico, N, Ferrara, F, Biancafarina, A, Tamini, N, Sinibaldi, G, Tuminello, F, Galleano, R, Sasia, D, Bragaglia, L, de Manzoni Garberini, A, Pesce, A, Cassaro, F, Venturelli, P, Canu, G, Esposito, G, Campanelli, M, Cardia, R, Ricciardiello, M, Sagnotta, A, Canonico, G, De Marco, G, Cappiello, A, Pinotti, E, Carlei, F, Lisi, G, Bagaglini, G, Farrugia, M, Meima - van Praag, E, Monteiro, C, Pereira, M, Botelho, P, Quigley, A, O'Neill, A, Gaule, L, Crone, L, Arnold, A, Grama, F, Beuca, A, Tulina, I, Litvin, A, Panyko, A, Ossola, M, Trujillo Diaz, J, Marin Santos, J, Alonso Batanero, E, Gortazar de las Casas, S, Soldevila Verdeguer, C, Colas-Ruiz, E, Talal El-Abur, I, Garcia Dominguez, M, Delorme, M, Sauvain, M, Ozmen, B, Ozkan, B, Calikoglu, F, Kural, S, Zafer, F, Kaya, Y, Yalcinkaya, A, Kargici, K, Tepe, M, Tatar, O, Kabadayi, E, Yildirim, A, Hurmuzlu, D, Korkmaz, K, Sharma, P, Troller, R, Hagan, N, Mooney, J, Light, A, Tansey, M, Bhojwani, D, Mcging, R, Mallon, A, Fadel, M, Spilsbury, C, James, R, O'Brien, S, Isaac, A, Balasubramanya, S, Sadik, H, Gala, T, Chen, J, Turner, B, Goh, E, Hassan, K, Karam, M, Mason, P, Tzoumas, N, Noton, T, Seehra, J, Ahmed, N, Motiwale, R, Tanna, V, Argyriou, A, Bylapudi, S, Grace, N, Latif, S, Hounat, A, Kiam, J, Zaidi, M, Elsamani, K, Hughes, C, Suresh, A, Sinan, L, El-Dalil, D, Khoo, E, Salim, E, Stark, D, Minhas, N, Fowler, G, Rees, E, Giudiceandrea, I, Bardon, A, Jayawardena, P, Dieseru, N, Murphy, A, Yates, C, Ziolkowska, K, Rafie, A, Khoda, F, Okocha, M, Ashdown, T, Vitish-Sharma, P, Gilliland, J, Toh, S, Jones, K, Devine, A, Berry, A, Mcdonnell, S, Olivier, J, Richardson, G, Lim, H, Slim, N, Elsayeh, K, Sammour, T, Sarpanov, A, Belev, N, Dimitrov, D, Dusek, T, Ntomi, V, Sotiropoulos, G, Theodorou, D, Nikiteas, N, Balalis, D, Antropoli, C, Altomare, D, Luglio, G, De Palma, G, Pedrazzani, C, Simonelli, L, Brozzetti, S, Porcu, A, Massani, M, Grazi, G, Izzo, F, Delrio, P, Restini, E, Chetta, G, Lantone, G, Ferrari, G, Lucchi, A, De Prizio, M, Caristo, G, Borghi, F, Petrucciani, N, Huscher, C, Cocorullo, G, Tonini, V, Medas, F, Sica, G, Cillara, N, Anastasi, A, Bianco, F, Giuliani, A, Carlini, M, Selvaggi, F, Sammarco, G, Ozolins, A, Malasonoks, A, Andrejevic, P, Tanis, P, van de Ven, A, Gerhards, M, Ribeiro da Silva, B, Silva, A, Lima, M, Kavanagh, D, Mccawley, N, Bintintan, V, Karamarkovic, A, Sanz Ortega, G, De Andres-Asenjo, B, Nevado Garcia, C, Garcia Florez, L, Segura-Sampedro, J, Blas Laina, J, Ponchietti, L, Buchwald, P, Gialamas, E, Ozben, V, Rencuzogullari, A, Gecim, I, Altinel, Y, Isik, O, Yoldas, T, Isik, A, Leventoglu, S, Erturk, M, Guner, A, Guler, S, Attaallah, W, Ugur, M, Ozbalci, G, Marzook, H, Eardley, N, Smolarek, S, Morgan, R, Roxburgh, C, Lala, A, Salama, Y, Singh, B, Khanna, A, Evans, M, Shaikh, I, Maradi Thippeswamy, K, Appleton, B, Moug, S, Smith, I, Smart, N, Shah, P, Williams, G, Khera, G, Goede, A, Varcada, M, Parmar, C, Duff, S, Hargest, R, Marriott, P, Speake, D, Ben Sassi, A, Furfaro, B, Daudu, D, Golijanin, N, Yek, W, Capasso, G, Mansour, L, Niu, N, Seow, W, Hamidovic, A, Kulovic, E, Letic, E, Aljic, A, Helez, M, Banji-Kelan, A, Dimitrova, N, Kavradjieva, P, Ivanov, V, Jukaku, A, Hadzhiev, D, Gabarski, A, Karamanliev, M, Vladova, P, Iliev, S, Yotsov, T, Epsilonupsilonsigmataualphathetaiotaomicronupsilon, E, Vetsa, K, Stavrinidou, O, Papatheodorou, P, Liassides, T, Georgiou, T, Al Nassrallah, M, Altaf, R, Negametzyanov, M, Zagibova, D, Foltys, F, Stefanova, H, Paspala, A, Bompetsi, G, Sidiropoulos, T, Stamopoulos, P, Triantafyllou, A, Theodoropoulos, C, Kimpizi, A, Palyvou, T, Charalabopoulos, A, Syllaios, A, Schizas, D, Liatsou, E, Baili, E, Vagios, I, Tomara, N, Davakis, S, Palumbo, A, Foroni, F, Dibra, R, Papagni, V, Urbani, A, Rossin, E, Nezi, G, Romano, P, Amendola, A, Esposito, E, Manigrasso, M, Anoldo, P, Vertaldi, S, Gecchele, G, Sabrina, Z, Guerci, C, Cammarata, F, Lamperti, G, Zaffaroni, G, Benuzzi, L, Ferrario, L, Cigognini, M, Mazzeo, C, Badessi, G, Pintabona, G, Fassari, A, Mingoli, A, Cirillo, B, D'Alterio, C, Brachini, G, Tancredi, M, Zambon, M, Aulicino, M, Sapienza, P, Liberatore, P, Scanu, A, Feo, C, Iacomino, A, Pelizzo, P, Rossi, S, Vigna, S, Grossi, U, Grillo, V, Agnes, A, Schena, C, Marincola, G, Oddi, A, Perotti, B, Mario, V, Perri, P, Zazza, S, Aversano, A, Scala, D, Di Lauro, K, Leongito, M, Piccirillo, M, Patrone, R, Capuzzolo, S, Vignotto, C, Bao, Q, Giuseppe, C, Angarano, E, Marino, F, Pezzolla, F, Gigante, G, Magistro, C, Crippa, J, Maspero, M, Carnevali, P, Trapani, R, Zonta, S, Agostinelli, L, Vittori, L, Romeo, L, Doria, E, Farnesi, F, Danna, R, Andolfi, E, Pellicano', G, Angelini, M, Scricciolo, M, Zanframundo, C, Ciulli, C, Ripamonti, L, Cigagna, L, Oldani, M, Larcinese, A, Rossi, D, Picone, E, Crescentini, G, Marano, A, Migliore, M, Giuffrida, M, Palagi, S, Testa, V, Borrello, A, Lucarini, A, Garofalo, E, Canali, G, Orlandi, P, Nervegna, F, Marchegiani, F, Damoli, I, Licata, A, Trovato, C, Alicata, F, Sardo, F, Milazzo, M, Randisi, B, Dominici, D, Sartarelli, L, Zanni, M, Pisanu, A, Soddu, C, Delogu, D, Erdas, E, Campus, F, Cappellacci, F, Casti, F, Marcialis, J, Atzeni, J, Sensi, B, Franceschilli, M, Bellato, V, Cannavera, A, Putzu, G, di Mola, F, Picardi, B, Solinas, L, Loponte, M, Rossi del Monte, S, Di Martino, C, Linari, C, Spagni, G, Capezzuoli, L, Tirloni, L, Nelli, T, Caridi, A, Elter, C, Camassa, M, D'Amico, S, Bargellini, T, Incollingo, P, Montuori, M, Maffione, F, Romano, L, Valiyeva, S, Spoletini, D, Menegon Tasselli, F, Sciaudone, G, Selvaggi, L, Menna, M, De Paola, G, Fulginiti, S, Truskovs, A, Weiss, C, Saknitis, G, Rauscher, J, Larnovskis, J, Jeyarajan-Davidsson, M, Nitisa, D, Gille, N, Reiser, S, Roshan, M, Leseman, C, van Dalen, A, Top, C, Detering, R, Matos, C, Silva, C, Pinto, D, Mendes, J, Couto, J, Leite, M, Velez, C, Damasio Cotovio, M, Cinza, A, Pedroso de Lima, R, Boyle, E, Yang, H, Banerjee, I, Rahmat, S, Afzal, Z, Reid, C, Dumitrascu, F, Croyle, J, Gressmann, K, Cullen, N, Graham, A, Nasehi, A, Montano King, C, Martin, B, Stokell, C, Sanderson, N, Farnan, R, Jassim, S, Chan, B, Chua Vi Long, K, Kaka, N, Pandey, S, Neo, W, Chitul, A, Bezede, C, Cincilei, D, David, A, Blaga, M, Blaga, S, Fagarasan, V, Khetagurova, M, Rodimov, S, Kapustina, A, Mekhralyzade, A, Zabiyaka, M, Jankovic, U, Cuk, V, Hajska, M, Dubovsky, M, Hrosova, M, Ferancikova, N, Camarero Rodriguez, E, Laguna Alcantara, F, Adarraga, J, Jezieniecki, C, Ruiz Soriano, M, Gomez Sanz, T, Suarez, A, Sanchez Garcia, C, Cifrian Canales, I, Llosa Perez, J, Merayo, M, Urbieta, A, Gegundez Simon, A, Tone, J, Gazo Martinez, J, Vicario Bravo, M, Chavarrias, N, Gil Catalan, A, Oseira, A, Villalonga, B, Jeri, S, Perez Calvo, J, Nogues, A, Cros, B, Yanez, C, Utrilla Fornals, A, Roldon Golet, M, Colsa, P, Gimenez Maurel, T, Axmarker, T, Chevallay, M, Pham, T, Sel, E, Atar, C, Aba, M, Sarkin, M, Akkaya, Y, Durmaz, A, Gullu, H, Boga, A, Aktas, A, Bakar, B, Demirel, M, Hysejni, X, Taser, M, Guzel, O, Bozbiyik, O, Ozen, D, Olmez, M, Uyar, B, Gulcek, E, Kayacan, G, Atici, N, Gul, O, Altiner, S, Ibis, B, Altunsu, S, Banaz, T, Diler, C, Demirbas, I, Usta, M, Erkul, O, Orman, R, Salih, S, Utkan, N, Acil, C, Ozgur, E, Maddahali, M, Turhan, A, Eskici, A, Ular, B, Dogru, M, Ozturk, O, Arslan, E, Panahi Sharif, A, Dikmen, E, Ates, J, Bircan, R, Cavus, T, Sever, A, Balak, B, Duman, E, Altay, L, Emanet, O, Cullen, F, Tan, J, Nathan, A, Rottenberg, A, Williams, C, Mitrofan, C, Xu, D, Bawa, J, Morris, P, Gordon, D, Richmond, G, Hui, J, Ighomereho, O, Rocks, R, Mccabe, S, Fitzpatrick, A, Nicoletti, J, Auterson, L, Darrah, N, Soh, V, Ong, C, Utukuri, M, Gallagher, C, Stuart, L, Hipolito, M, Douglas, N, Ghazal, R, Parris, G, Catchpole, J, Bryden, M, Jamal, S, Karim, Z, Lyon-Dean, C, Rowley, G, Lee, K, Whitehurst, O, Mirza, A, Sheikh, F, Yousaf, H, Bilbao, J, Sinclair, R, Takar, S, Kressel, H, Chan, V, Schack, K, Osborne, R, Baldemor, S, Smyth, S, Gilmour, S, Ting, A, Bozonelou, I, Saunders, P, Qhaireel Anwar, Q, Tirimanna, R, Jauhari, S, Gardener, A, Walker, B, Wenban, C, Reddy, H, Conway-Jones, R, Loganathan, S, Clynch, A, James, C, Matey, E, Cameron, F, Roberts, W, Gicquel, A, Milliken, C, Forbes, J, Rubinchik, P, Azmi, A, Hawkes, C, Cornett, L, Adarkwah, P, Mcconville, R, O'Hara, S, Tijare, C, Parkes, J, Yao, L, Ahmad, R, Shafiq, U, Mhaisalkar, A, Gurung, A, de Stadler, K, Elias, S, Thomas, T, Madras, A, Jani, A, Daler, H, Tong, K, Sundaralingam, S, Szal, A, Khan, A, O'Sullivan, C, Baker, E, Joseph-Gubral, J, Hadley, E, Trivedi, R, Igwelaezoh, E, Barton, H, Allison, W, Hurst, W, Alam, F, Parkes, I, Jamshaid, M, Azizan, N, Burgher, T, Afzal, A, Eltilib, I, Zahid, M, Sadiq, O, Lloyd, A, Ho, R, Brazukas, A, Li, C, Kamdar, M, Mohamed Nazeer, M, Mighiu, A, Kim, D, Wilkins, L, Kuo, L, Rafe, T, Maduka, D, Cheema, H, Farag, K, Abdellatif, M, Nzewi, R, Kruczynska, A, Grasselli, H, Yousuff, M, Bassi, R, Mann, A, Chopra, J, Shaikh, M, D Sa, S, Tsimplis, V, Ghanchi, A, Skene, E, Asim, K, Zaheer, M, Chan, S, Dalton, H, Gibbons, K, Adderley, O, Chukwujindu, I, Jayasuriya, I, Sivanu, K, Borumand, M, Chick, G, Bridges, I, Tomlin, J, Mckenna, J, Nandra, N, Grieco, C, Quek, F, Mercer, R, Brankin-Frisby, T, Sattar, A, Aslam, A, Edelsten, E, Shafi, S, Kouli, T, Ford, V, Gurung, F, Fernandes, M, Deader, N, Ponniah, R, Jamieson, S, Davies, A, Taubwurcel, J, Aung, M, Desai, R, Begum, S, Jamadar, T, Kangatharan, A, Rzeszowski, B, Ho, C, Yap, S, Prendergast, M, Sethi, R, Duku, A, Lowe, C, Bray, J, Ghobrial, M, Nichita, V, Wagstaff, A, Rengasamy, E, Abu Hassan, F, Mahmood, H, Savill, N, Shah, S, Almeida, T, Edwards, A, Catchpole, B, Halford, Z, Carmichael, A, Alsusa, H, Boyd, M, Williams, J, Feyi-Waboso, J, Patel, M, Zeidan, Z, Bailey, E, Bapty, J, Brazkiewicz, M, Tremlett, A, Pringle, H, Mankal, S, Chung, W, Parry-Jones, E, Anderson, K, Mcforrester, A, Stanley, A, Hoather, A, Wise, H, Laid, I, Scriven, J, Braniste, A, Wilson, A, Le Blevec, L, Pakunwanich, N, Evans, N, Chong, H, White, C, Hunter, J, Haque, M, Vanalia, P, Murdoch, S, Choudhary, T, Mccann, A, Harun, A, Shah, H, Hunt, S, Shafiq, Y, Bickley-Morris, E, Emms, L, Dare, M, Akula, Y, Deliyannis, E, Mayes, F, Ellacott, M, Zagorac, Z, Farren, A, Manning, C, Hughed, C, Stewart, E, Lim, K, Chohan, N, Thaker, A, Thompson, B, Ahari, D, Burdekin, E, Okwu, U, Akintunde, A, Lhaf, F, Douthwaite, J, Govindan, R, Leelamanthep, S, Gull, E, Wright, F, Dundas, L, Mackdermott, N, Burchi-Khairy, T, Campbell, I, Walsh, J, Yeo, J, Meehan, S, Banerjee, D, Fu, M, Kawka, M, Ali, T, Hussain, Z, Thomas, C, Ahmad, H, Moroney, J, Yick, C, Risquet, R, Ntuiabane, D, Shimato, M, Khan, M, Ilangovan, S, Vaselli, N, Smithers, R, Uhanowita Marage, R, Valnarov-Boulter, A, Kayran, J, Banerjee, M, Parekh-Hill, N, Hooper, A, Bowen, J, Jagdish, R, Mcquoid, C, Khan, N, O Hare, R, Jeffery, S, Zahid, A, Elsworth, C, Walter, L, Dhillon, S, Rao, S, Anthony, A, Ashaye, A, Phillips, N, Faderani, R, Pengelly, S, Choi, S, Kwak, S, Lau, Y, Bagheri, K, Ong, D, Kerr, E, Falconer, K, Clancy, N, Douglas, S, Zhang, Y, Greenfield, F, Mutanga, I, Mcalinden, J, Willis, L, Adefolaju, A, Agarwal, H, Barter, R, Harris, G, Spencer, G, Lee, M, V Vadiveloo, T, Herbert, G, Patel, R, Shah, M, El Falaha, S, Wong, C, Soare, C, Akram, J, Bozhkova, L, Ma, Y, Vo, U, Tan, H, Leto, L, Kamal, M, Hadzhieva, E, Krastev, P, Tonchev, P, Kokkinos, G, Pozotou, I, Sabbagh, D, Votava, J, St, F, Koliakos, N, Tsaparas, P, Zografos, G, Mantas, D, Tsourouflis, G, Fradelos, E, Trigiante, G, Labellarte, G, Resta, G, Capelli, G, D'Amore, A, Verlingieri, V, Campagnaro, T, Maffioli, A, Viscosi, F, De Lucia, C, Meneghini, S, Fancellu, A, Colella, M, Biondi, A, De Peppo, V, Pace, U, Albino, V, Gattulli, D, Piangerelli, A, Kalivaci, D, Sisto, G, Mazzola, M, Caneparo, A, Lunghi, E, Nespoli, L, Angrisani, M, Langone, A, Gelarda, E, Virgilio, E, Angelini, E, Fornasier, C, Asero, S, Filippone, E, Frongia, F, Calo, P, Panaccio, P, Ipponi, P, Gili, S, Braccio, B, Tiesi, V, Stolcers, K, Kokaine, L, Novikovs, V, Capel, L, Bastiaenen, V, Heijmans, H, Henriques, S, Gan, S, Ramanayake, H, Nolan, M, Temperley, H, Ciofic, E, Pop, B, Kurtenkov, M, Jovanovic, M, Vician, M, Egea Arias, P, Beltran de Heredia, J, Labalde Martinez, M, De Santiago Alvarez, I, Alvarez-Gallego, M, Rodriguez Artigas, J, Dwidar, O, Korkmaz, H, Eray, I, Meric, S, Aydin, R, Cetin, B, Karaca, B, Kuyumcu, O, Yuksel, E, Uprak, T, Karabulut, K, Kavukcu, E, Mansor, A, Hackett, R, Zammit-Maempel, M, Sabaratnam, R, Maan, A, Ferarrio, I, Dixon, L, Halai, H, Sethi, S, Nelson, L, Grassam-rowe, A, Krishnan, E, Deeny, D, Mckeever, M, George Pandeth, A, Dhavala, P, Sreenivasan, S, Sundaram Venkatesan, G, Zhu, L, Atiyah, Z, Gregory, J, Morey, T, Seymour, Z, Holdsworth, L, Abdelmahmoud, S, Bourhill, J, Bisheet, G, Shaw, J, Kulkarni, K, Kumarakulasingam, P, Pillay, S, Al-Habsi, R, Kungwengwe, G, Richards, J, Davoudi, K, Ibrahim, B, Tailor, B, Zayed, M, Chen, F, Bailey, S, Sheefat, S, Nawaz, G, Pawar, R, Marsh, S, Sam, Z, Roy Bentley, S, Simpson, C, Lim, Y, Ooi, R, Toh, W, Mannion, P, Lovett, A, Kincius, A, Hussein, S, Kirby, E, Beckett, R, Salmon, J, Glynn, T, Choo, S, Lyons, S, Browne, D, Ravindran, W, Ahmad, S, Zhu, X, Mcnulty, J, Mccarthy, L, Ng, J, Karmally, Z, Mcteir, K, Hanna, M, Tan, E, Namdeo, S, Schembri, R, Pusey, E, Sgro A., Blanco-Colino R., Ahmed W. U. R., Brindl N., Gujjuri R. R., Lapolla P., Mills E. C., Perez-Ajates S., Soares A. S., Varghese C., Xu W., McLean K. A., Chapman S. J., Espin-Basany E., Glasbey J. C., Mihaljevic A., Nepogodiev D., Pata F., Pellino G., Pockney P., Dudi-Venkata N. N., Egoroff N., Ludbrook I., Raubenheimer K., Richards T., Delibegovic S., Salibasic M., Amjad T., Dorr-Harim C., Gedeon N., Gsenger J., Tachezy M., Bini S., Gallo G., Gori A., Picciariello A., Podda M., Riboni C., Machatschek M. J., Nguyen A., Jakubauskas M., Kryzauskas M., Poskus T., Kuiper S. Z., Wang J., Wells C. I., Bissett I. P., Augestad K. M., Steinholt I., Vieira B. N., Juloski J., Anabitarte Bautista O., Kasmy El Kasmy Y., Martin-Borregon P., Ossola Revilla M., Van Straten S., Aktas M. K., Baki B. E., Akhbari M., Baker D., Bhatia S., Brown S., Cambridge W., Kamarajah S. K., Khaw R. A., Kouli O., Murray V., Trout I., Yasin I., Wong J. Y., Reyhani H., Wong K. H. F., Pancharatnam R., Chia W. L., Walmsley A., Hassane A., Saeed D., Wang B., Walters B., Nowinka Z., Alsaif A., Mirza M., Foster K., Luu J., Kakodkar P., Hughes J. T., Yogarajah T., Antypas A., Rahman A., Bradbury M., McLarnon M., Nagi S., Riad A. M., Erotocritou M., Kyriacou H., Kaminskaite V., Alfadhel S., Fatimah Hussain Q., Handa A., Massy-Westropp C., Custovic S., Dimov R., Mughal H., Slavchev M., Ivanov T., Gouvas N., Hegazi A., Kocian P., Kjaer M. D., Mark-Christensen A., Papakonstantinou D., Machairas N., Triantafyllou T., Garoufalia Z., Korkolis D., Castaldi A., Giaccari S., Spolverato G., Pagano G., Milone M., Turri G., Colombo F., Cucinotta E., Poillucci G., Perra T., Tutino R., Belia F., Coletta D., Belli A., Rega D., Cianci P., Pirozzolo G., Di Lena M., Perrone F., Giani A., Lovisetto F., Grassia M., Pipitone Federico N. S., Ferrara F., Biancafarina A., Tamini N., Sinibaldi G., Tuminello F., Galleano R., Sasia D., Bragaglia L., de Manzoni Garberini A., Pesce A., Cassaro F., Venturelli P., Canu G. L., Esposito G., Campanelli M., Cardia R., Ricciardiello M., Sagnotta A., Canonico G., De Marco G., Cappiello A., Pinotti E., Carlei F., Lisi G., Bagaglini G., Farrugia M., Meima - van Praag E. M., Monteiro C., Pereira M., Botelho P., Quigley A., O'Neill A., Gaule L., Crone L., Arnold A., Grama F., Beuca A., Tulina I., Litvin A., Panyko A., Ossola M. E., Trujillo Diaz J., Marin Santos J. M., Alonso Batanero E., Gortazar de las Casas S., Soldevila Verdeguer C., Colas-Ruiz E., Talal El-Abur I., Garcia Dominguez M., Delorme M., Sauvain M., Ozmen B. B., Ozkan B. B., Calikoglu F., Kural S., Zafer F., Kaya Y., Yalcinkaya A., Kargici K., Tepe M. D., Tatar O. C., Kabadayi E., Yildirim A., Hurmuzlu D., Korkmaz K., Sharma P., Troller R., Hagan N., Mooney J., Light A., Tansey M., Bhojwani D., McGing R. M., Mallon A., Fadel M., Spilsbury C., James R., O'Brien S., Isaac A., Balasubramanya S., Sadik H., Gala T., Chen J. Y., Turner B., Goh E., Hassan K., Karam M., Mason P., Tzoumas N., Noton T., Seehra J. K., Ahmed N., Motiwale R., Tanna V., Argyriou A., Bylapudi S. K., Grace N., Latif S., Hounat A., Kiam J. S., Zaidi M., Elsamani K., Hughes C., Suresh A., Sinan L. O. H., El-Dalil D., Khoo E. J. M., Salim E. E., Stark D., Minhas N., Fowler G., Rees E., Giudiceandrea I., Bardon A., Jayawardena P., Dieseru N., Murphy A., Yates C., Ziolkowska K., Rafie A., Khoda F., Okocha M., Ashdown T., Vitish-Sharma P., Gilliland J., Toh S., Jones K., Devine A., Berry A., McDonnell S., Olivier J., Richardson G., Lim H. J., Slim N., Elsayeh K., Sammour T., Sarpanov A., Belev N., Dimitrov D., Dusek T., Ntomi V., Sotiropoulos G. C., Theodorou D., Nikiteas N., Balalis D., Antropoli C., Altomare D. F., Luglio G., De Palma G. D., Pedrazzani C., Simonelli L., Brozzetti S., Porcu A., Massani M., Grazi G. L., Izzo F., Delrio P., Restini E., Chetta G., Lantone G., Ferrari G., Lucchi A., De Prizio M., Caristo G., Borghi F., Petrucciani N., Huscher C., Cocorullo G., Tonini V., Medas F., Sica G., Cillara N., Anastasi A., Bianco F., Giuliani A., Carlini M., Selvaggi F., Sammarco G., Ozolins A., Malasonoks A., Andrejevic P., Tanis P., van de Ven A., Gerhards M., Ribeiro da Silva B., Silva A., Lima M. J., Kavanagh D., McCawley N., Bintintan V., Karamarkovic A., Sanz Ortega G., De Andres-Asenjo B., Nevado Garcia C., Garcia Florez L. J., Segura-Sampedro J. J., Blas Laina J. L., Ponchietti L., Buchwald P., Gialamas E., Ozben V., Rencuzogullari A., Gecim I. E., Altinel Y., Isik O., Yoldas T., Isik A., Leventoglu S., Erturk M. S., Guner A., Guler S. A., Attaallah W., Ugur M., Ozbalci G. S., Marzook H., Eardley N., Smolarek S., Morgan R., Roxburgh C., Lala A. K., Salama Y., Singh B., Khanna A., Evans M., Shaikh I., Maradi Thippeswamy K., Appleton B., Moug S., Smith I., Smart N., Shah P., Williams G., Khera G., Goede A., Varcada M., Parmar C., Duff S., Hargest R., Marriott P., Speake D., Ben Sassi A., Furfaro B., Daudu D., Golijanin N., Yek W. Y., Capasso G., Mansour L. T., Niu N., Seow W., Hamidovic A., Kulovic E., Letic E., Aljic A., Helez M., Banji-Kelan A., Dimitrova N., Kavradjieva P., Ivanov V., Jukaku A., Hadzhiev D., Gabarski A., Karamanliev M., Vladova P., Iliev S., Yotsov T., Epsilonupsilonsigmataualphathetaiotaomicronupsilon Eta., Vetsa K., Stavrinidou O., Papatheodorou P., Liassides T., Georgiou T., Al Nassrallah M., Altaf R., Negametzyanov M., Zagibova D., Foltys F., Stefanova H., Paspala A., Bompetsi G., Sidiropoulos T., Stamopoulos P., Triantafyllou A., Theodoropoulos C., Kimpizi A., Palyvou T., Charalabopoulos A., Syllaios A., Schizas D., Liatsou E., Baili E., Vagios I., Tomara N., Davakis S., Palumbo A., Foroni F., Dibra R., Papagni V., Urbani A., Rossin E., Nezi G., Romano P., Amendola A., Esposito E., Manigrasso M., Anoldo P., Vertaldi S., Gecchele G., Sabrina Z. S., Guerci C., Cammarata F., Lamperti G. M. B., Zaffaroni G., Benuzzi L., Ferrario L., Cigognini M., Mazzeo C., Badessi G., Pintabona G., Fassari A., Mingoli A., Cirillo B., D'Alterio C., Brachini G., Tancredi M., Zambon M., Aulicino M., Sapienza P., Liberatore P., Scanu A. M., Feo C. F., Iacomino A., Pelizzo P., Rossi S., Vigna S. A., Grossi U., Grillo V., Agnes A., Schena C. A., Marincola G., Oddi A., Perotti B., Mario V., Perri P., Zazza S., Aversano A., Scala D., Di Lauro K., Leongito M., Piccirillo M., Patrone R., Capuzzolo S., Vignotto C., Bao Q. R., Giuseppe C., Angarano E., Marino F., Pezzolla F., Gigante G., Magistro C., Crippa J., Maspero M., Carnevali P., Trapani R., Zonta S., Agostinelli L., Vittori L., Romeo L., Doria E., Farnesi F., Danna R., Andolfi E., Pellicano' G. A., Angelini M., Scricciolo M., Zanframundo C., Ciulli C., Ripamonti L., Cigagna L., Oldani M., Larcinese A., Rossi D., Picone E., Crescentini G., Marano A., Migliore M., Giuffrida M. C., Palagi S., Testa V., Borrello A., Lucarini A., Garofalo E., Canali G., Orlandi P., Nervegna F., Marchegiani F., Damoli I., Licata A., Trovato C., Alicata F., Sardo F., Milazzo M., Randisi B., Dominici D. M., Sartarelli L., Zanni M., Pisanu A., Soddu C., Delogu D., Erdas E., Campus F., Cappellacci F., Casti F., Marcialis J., Atzeni J., Podda M. G., Sensi B., Franceschilli M., Bellato V., Cannavera A., Putzu G., di Mola F. F., Picardi B., Solinas L., Loponte M., Rossi del Monte S., Di Martino C., Linari C., Spagni G., Capezzuoli L., Tirloni L., Nelli T., Caridi A., Elter C., Camassa M., D'Amico S., Bargellini T., Incollingo P., Montuori M., Maffione F., Romano L., Valiyeva S., Spoletini D., Menegon Tasselli F., Sciaudone G., Selvaggi L., Menna M. P., De Paola G., Fulginiti S., Truskovs A., Weiss C., Saknitis G., Rauscher J. T. R., Larnovskis J., Jeyarajan-Davidsson M., Nitisa D., Gille N., Reiser S. C., Roshan M. H. K., Leseman C., Chen J., van Dalen A. S., Top C., Detering R., Matos C., Silva C., Pinto D., Mendes J., Couto J., Leite M., Velez C., Damasio Cotovio M., Cinza A. M., Pedroso de Lima R., Boyle E., Yang H. W., Banerjee I., Rahmat S., Afzal Z., Reid C., Dumitrascu F., Croyle J. A., Gressmann K., Cullen N., Graham A., Nasehi A., Montano King C., Martin B., Stokell C., Sanderson N., Farnan R., Jassim S., Chan B., Chua Vi Long K., Kaka N., Pandey S., Neo W. X., Chitul A., Bezede C., Cincilei D., David A., Blaga M., Blaga S. N., Fagarasan V., Khetagurova M., Rodimov S., Kapustina A., Mekhralyzade A., Zabiyaka M., Jankovic U., Cuk V., Hajska M., Dubovsky M., Hrosova M., Ferancikova N., Camarero Rodriguez E., Laguna Alcantara F., Adarraga J., Jezieniecki C., Ruiz Soriano M., Gomez Sanz T., Suarez A., Sanchez Garcia C., Cifrian Canales I., Llosa Perez J., Merayo M., Urbieta A., Gegundez Simon A., Tone J. F., Gazo Martinez J., Vicario Bravo M., Chavarrias N., Gil Catalan A., Oseira A., Villalonga B., Jeri S., Perez Calvo J., Nogues A., Cros B., Yanez C., Utrilla Fornals A., Roldon Golet M., Colsa P., Gimenez Maurel T., Axmarker T., Chevallay M., Pham T. V., Sel E. K., Atar C., Aba M., Sarkin M., Akkaya Y. M., Durmaz A. G., Gullu H. F., Boga A., Aktas A., Bakar B., Demirel M. T., Hysejni X., Taser M., Guzel O. R., Bozbiyik O., Ozen D., Olmez M., Uyar B., Gulcek E., Kayacan G. S., Atici N., Gul O. F., Altiner S., Ibis B., Altunsu S., Banaz T., Diler C., Demirbas I., Usta M. A., Erkul O., Orman R., Salih S., Utkan N. Z., Acil C., Ozgur E., Maddahali M., Turhan A. B., Eskici A. B., Ular B., Dogru M., Ozturk O. U., Arslan E. R., Panahi Sharif A., Dikmen E., Ates J., Bircan R., Cavus T., Sever A. E., Balak B., Duman E., Altay L., Emanet O., Cullen F., Tan J. Y., Nathan A., Rottenberg A., Williams C. Y., Mitrofan C. G., Xu D., Bawa J. H., Morris P., Gordon D., Richmond G., Hui J. C., Ighomereho O., Rocks R., McCabe S., Fitzpatrick A., Nicoletti J., Auterson L., Darrah N., Soh V. W. Y., Ong C. S., Utukuri M., Gallagher C., Stuart L. M., Hipolito M., Douglas N., Ghazal R., Parris G., Catchpole J., Bryden M., Jamal S., Karim Z., Lyon-Dean C., Rowley G., Lee K. S., Whitehurst O., Mirza A., Sheikh F., Yousaf H., Bilbao J., Sinclair R., Takar S., Kressel H., Chan V., Schack K., Osborne R., Baldemor S., Smyth S., Gilmour S., Ting A., Bozonelou I., Saunders P., Qhaireel Anwar Q. A., Tirimanna R., Jauhari S., Gardener A., Walker B., Wenban C., Reddy H., Conway-Jones R., Loganathan S., Clynch A., James C., Matey E., Cameron F., Roberts W., Gicquel A., Milliken C., Forbes J., Rubinchik P., Azmi A., Hawkes C., Cornett L., Adarkwah P., McConville R., O'Hara S., Tijare C., Parkes J., Yao L., Ahmad R., Shafiq U., Mhaisalkar A., Gurung A., de Stadler K., Elias S., Thomas T., Madras A., Jani A., Daler H. K., Tong K. S., Sundaralingam S. S., Szal A., Khan A., O'Sullivan C., Baker E., Joseph-Gubral J., Hadley E., Trivedi R., Igwelaezoh E., Barton H., Allison W., Hurst W., Alam F., Parkes I., Jamshaid M., Azizan N., Burgher T., Afzal A., Eltilib I., Zahid M., Sadiq O., Lloyd A., Ho R., Brazukas A., Li C. H., Kamdar M., Mohamed Nazeer M. N., Mighiu A., Kim D., Wilkins L., Kuo L., Rafe T., Maduka D., Cheema H., Farag K., Abdellatif M., Nzewi R., Kruczynska A., Grasselli H., Yousuff M., Bassi R., Mann A. K., Chopra J., Shaikh M., D Sa S., Tsimplis V., Ghanchi A., Skene E., Asim K., Zaheer M., Chan S., Dalton H., Gibbons K., Adderley O., Chukwujindu I., Jayasuriya I., Sivanu K., Borumand M., Chick G., Bridges I., Tomlin J., McKenna J., Nandra N., Grieco C., Quek F. F., Mercer R., Brankin-Frisby T., Sattar A., Aslam A., Edelsten E., Shafi S., Kouli T., Ford V., Gurung F., Fernandes M., Deader N., Ponniah R., Jamieson S., Davies A., Taubwurcel J., Aung M. T., Desai R., Begum S., Jamadar T., Kangatharan A., Rzeszowski B., Ho C., Yap S. H. K., Prendergast M., Sethi R., Duku A., Lowe C., Bray J., Ghobrial M., Nichita V., Wagstaff A., Rengasamy E., Abu Hassan F., Mahmood H., Savill N., Shah S., Almeida T., Edwards A., Catchpole B., Halford Z., Carmichael A., Alsusa H., Boyd M., Williams J., Feyi-Waboso J., Patel M., Zeidan Z., Bailey E., Bapty J., Brazkiewicz M., Tremlett A., Pringle H., Mankal S., Chung W., Parry-Jones E., Anderson K., Mcforrester A., Stanley A., Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H. L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E. G., Lim K. H., Chohan N., Thaker A., Thompson B., Ahari D., Burdekin E., Okwu U., Akintunde A., Lhaf F., Douthwaite J., Govindan R., Leelamanthep S., Gull E., Wright F., Dundas L., Mackdermott N., Burchi-Khairy T., Campbell I., Walsh J., Yeo J. Y., Meehan S., Banerjee D., Fu M., Kawka M., Ali T., Hussain Z., Thomas C., Ahmad H., Moroney J., Yick C., Risquet R., Ntuiabane D., Shimato M., Khan M., Ilangovan S., Vaselli N. M., Smithers R., Uhanowita Marage R., Valnarov-Boulter A., Kayran J., Banerjee M., Parekh-Hill N., Hooper A., Bowen J., Jagdish R., Mcquoid C., Khan N., O Hare R., Jeffery S., Zahid A., Elsworth C., Walter L., Dhillon S., Rao S., Anthony A., Ashaye A., Phillips N., Faderani R., Pengelly S., Choi S., Kwak S. Y., Lau Y. H. L., Bagheri K., Ong D. Y. C., Kerr E., Falconer K., Clancy N., Douglas S., Zhang Y., Greenfield F., Mutanga I., McAlinden J., Willis L., Adefolaju A., Agarwal H., Barter R., Harris G., Spencer G., Lee M. W., V Vadiveloo T., Herbert G., Patel R., Shah M., El Falaha S., Wong C., Soare C., Akram J., Bozhkova L., Ma Y., Vo U. G., Tan H. W. N., Leto L., Kamal M. A., Hadzhieva E., Krastev P., Tonchev P., Kokkinos G., Pozotou I., Sabbagh D., Votava J., St F., Koliakos N., Tsaparas P., Zografos G., Mantas D., Tsourouflis G., Fradelos E., Trigiante G., Labellarte G., Resta G., Capelli G., D'Amore A., Verlingieri V., Campagnaro T., Maffioli A., Viscosi F., De Lucia C., Meneghini S., Fancellu A., Colella M., Biondi A., De Peppo V., Pace U., Albino V., Gattulli D., Piangerelli A., Kalivaci D., Sisto G., Mazzola M., Caneparo A., Lunghi E. G., Nespoli L. C., Angrisani M., Langone A., Gelarda E., Virgilio E., Angelini E., Fornasier C., Asero S., Filippone E., Frongia F., Calo P. G., Panaccio P., Ipponi P., Gili S., Braccio B., Tiesi V., Stolcers K., Kokaine L., Novikovs V., Capel L., Bastiaenen V., Heijmans H., Henriques S., Gan S. Z., Ramanayake H., Nolan M., Temperley H., Ciofic E., Pop B. A., Kurtenkov M., Jovanovic M., Vician M., Egea Arias P., Beltran de Heredia J., Labalde Martinez M., De Santiago Alvarez I., Alvarez-Gallego M., Rodriguez Artigas J. M., Dwidar O., Korkmaz H. K., Eray I. C., Meric S., Aydin R., Cetin B., Karaca B. E., Kuyumcu O. F., Yuksel E., Uprak T. K., Karabulut K., Kavukcu E., Mansor A., Hackett R., Zammit-Maempel M., Sabaratnam R., Maan A., Ferarrio I., Dixon L., Halai H., Sethi S., Nelson L., Grassam-rowe A., Krishnan E., Deeny D., McKeever M., George Pandeth A., Dhavala P., Sreenivasan S., Sundaram Venkatesan G., Zhu L., Atiyah Z., Gregory J., Morey T., Seymour Z., Holdsworth L., Abdelmahmoud S., Bourhill J., Bisheet G., Shaw J., Kulkarni K., Kumarakulasingam P., Pillay S., Al-Habsi R., Kungwengwe G., Richards J., Davoudi K., Ibrahim B., Tailor B., Zayed M., Chen F., Bailey S., Sheefat S., Nawaz G., Pawar R., Marsh S., Sam Z. H., Roy Bentley S., Simpson C., Hughes J., Lim Y., Ooi R., Toh W. H., Mannion P., Lovett A., Kincius A., Hussein S., Kirby E., Beckett R. G., Salmon J., Glynn T., Choo S. Y., Lyons S., Browne D., Ravindran W., Ahmad S., Zhu X., McNulty J., McCarthy L., Ng J., Karmally Z., McTeir K., Hanna M., Tan E., Namdeo S., Schembri R., and Pusey E.
- Abstract
Aim: Intraperitoneal drains are often placed during emergency colorectal surgery. However, there is a lack of evidence supporting their use. This study aimed to describe the efficacy and safety of intraperitoneal drain placement after emergency colorectal surgery. Method: COMPlicAted intra-abdominal collectionS after colorectal Surgery (COMPASS) is a prospective, international, cohort study into which consecutive adult patients undergoing emergency colorectal surgery were enrolled (from 3 February 2020 to 8 March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included rate and time-to-diagnosis of postoperative intraperitoneal collections, rate of surgical site infections (SSIs), time to discharge and 30-day major postoperative complications (Clavien–Dindo III–V). Multivariable logistic and Cox proportional hazards regressions were used to estimate the independent association of the outcomes with drain placement. Results: Some 725 patients (median age 68.0 years; 349 [48.1%] women) from 22 countries were included. The drain insertion rate was 53.7% (389 patients). Following multivariable adjustment, drains were not significantly associated with reduced rates (odds ratio [OR] = 1.56, 95% CI: 0.48–5.02, p = 0.457) or earlier detection (hazard ratio [HR] = 1.07, 95% CI: 0.61–1.90, p = 0.805) of collections. Drains were not significantly associated with worse major postoperative complications (OR = 1.26, 95% CI: 0.67–2.36, p = 0.478), delayed hospital discharge (HR = 1.11, 95% CI: 0.91–1.36, p = 0.303) or increased risk of SSIs (OR = 1.61, 95% CI: 0.87–2.99, p = 0.128). Conclusion: This is the first study investigating placement of intraperitoneal drains following emergency colorectal surgery. The safety and clinical benefit of drains remain uncertain. Equipoise exists for randomized trials to define the safety and efficacy of drains in emergency colorectal surgery.
- Published
- 2023
3. Biological Role of Tumor/Stromal CXCR4-CXCL12-CXCR7 in MITO16A/MaNGO-OV2 Advanced Ovarian Cancer Patients
- Author
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D'Alterio, C, Spina, A, Arenare, L, Chiodini, P, Napolitano, M, Galdiero, F, Portella, L, Simeon, V, Signoriello, S, Raspagliesi, F, Lorusso, D, Pisano, C, Colombo, N, Zannoni, G, Losito, N, De Cecio, R, Scognamiglio, G, Califano, D, Russo, D, Tuninetti, V, Piccirillo, M, Gargiulo, P, Perrone, F, Pignata, S, Scala, S, D'alterio C., Spina A., Arenare L., Chiodini P., Napolitano M., Galdiero F., Portella L., Simeon V., Signoriello S., Raspagliesi F., Lorusso D., Pisano C., Colombo N., Zannoni G. F., Losito N. S., De Cecio R., Scognamiglio G., Califano D., Russo D., Tuninetti V., Piccirillo M. C., Gargiulo P., Perrone F., Pignata S., Scala S., D'Alterio, C, Spina, A, Arenare, L, Chiodini, P, Napolitano, M, Galdiero, F, Portella, L, Simeon, V, Signoriello, S, Raspagliesi, F, Lorusso, D, Pisano, C, Colombo, N, Zannoni, G, Losito, N, De Cecio, R, Scognamiglio, G, Califano, D, Russo, D, Tuninetti, V, Piccirillo, M, Gargiulo, P, Perrone, F, Pignata, S, Scala, S, D'alterio C., Spina A., Arenare L., Chiodini P., Napolitano M., Galdiero F., Portella L., Simeon V., Signoriello S., Raspagliesi F., Lorusso D., Pisano C., Colombo N., Zannoni G. F., Losito N. S., De Cecio R., Scognamiglio G., Califano D., Russo D., Tuninetti V., Piccirillo M. C., Gargiulo P., Perrone F., Pignata S., and Scala S.
- Abstract
This study investigated the prognostic role of the CXCR4-CXCL12-CXCR7 axis in advanced epithelial ovarian cancer (EOC) patients receiving first-line treatment within the MITO16A/MaNGO-OV2 phase-IV trial. CXCR4-CXCL12-CXCR7 expression was evaluated in the epithelial and stromal component of 308 EOC IHC-stained tumor samples. The statistical analysis focused on biomarkers’ expression, their association with other variables and prognostic value. Zero-inflated tests, shrinkage, bootstrap procedures, and multivariable models were applied. The majority of EOC (75.0%) expressed CXCR4 and CXCR7, 56.5% expressed the entire CXCR4-CXCL12-CXCR7 axis, while only 4.6% were negative for CXCL12 and its cognate receptors, in regard to the epithelial component. Stromal CXCL12 and CXCR7, expressed in 11.2% and 65.5%, respectively, were associated with the FIGO stage. High CXCL12 in epithelial cancer cells was associated with shorter progression-free and overall survival. However, after adjusting for overfitting due to best cut-off multiplicity testing, the significance was lost. This is a wide-ranging, prospective study in which CXCR4-CXCL12-CXCR7 were systematically evaluated in epithelial and stromal components, in selected stage III-IV EOC. Although CXCL12 was not prognostic, epithelial expression identified high-risk FIGO stage III patients for PFS. These data suggest that it might be worth studying the CXCL12 axis as a therapeutic target to improve treatment efficacy in EOC patients.
- Published
- 2022
4. Intraperitoneal drain placement and outcomes after elective colorectal surgery: International matched, prospective, cohort study
- Author
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Sgro, A, Blanco-Colino, R, Ahmed, W, Brindl, N, Gujjuri, R, Lapolla, P, Mills, E, Perez-Ajates, S, Soares, A, Varghese, C, Xu, W, Mclean, K, Chapman, S, Espin-Basany, E, Glasbey, J, Mihaljevic, A, Nepogodiev, D, Pata, F, Pellino, G, Pockney, P, Dudi-Venkata, N, Egoroff, N, Ludbrook, I, Raubenheimer, K, Richards, T, Delibegovic, S, Salibasic, M, Amjad, T, Dorr-Harim, C, Gedeon, N, Gsenger, J, Tachezy, M, Bini, S, Gallo, G, Gori, A, Picciariello, A, Podda, M, Riboni, C, Machatschek, M, Nguyen, A, Jakubauskas, M, Kryzauskas, M, Poskus, T, Kuiper, S, Wang, J, Wells, C, Bissett, I, Augestad, K, Steinholt, I, Vieira, B, Juloski, J, Anabitarte Bautista, O, El Kasmy El Kasmy, Y, Martin-Borregon, P, Ossola Revilla, M, Van Straten, S, Aktas, M, Baki, B, Akhbari, M, Baker, D, Bhatia, S, Brown, S, Cambridge, W, Kamarajah, S, Khaw, R, Kouli, O, Murray, V, Trout, I, Yasin, I, Wong, J, Reyhani, H, Wong, K, Pancharatnam, R, Chia, W, Walmsley, A, Hassane, A, Saeed, D, Wang, B, Walters, B, Nowinka, Z, Alsaif, A, Mirza, M, Foster, K, Luu, J, Kakodkar, P, Hughes, J, Yogarajah, T, Antypas, A, Rahman, A, Bradbury, M, Mclarnon, M, Nagi, S, Riad, A, Erotocritou, M, Kyriacou, H, Kaminskaite, V, Alfadhel, S, Fatimah Hussain, Q, Handa, A, Massy-Westropp, C, Custovic, S, Dimov, R, Mughal, H, Slavchev, M, Ivanov, T, Gouvas, N, Hegazi, A, Kocian, P, Kjaer, M, Mark-Christensen, A, Papakonstantinou, D, Machairas, N, Triantafyllou, T, Garoufalia, Z, Korkolis, D, Castaldi, A, Giaccari, S, Spolverato, G, Pagano, G, Milone, M, Turri, G, Colombo, F, Cucinotta, E, Poillucci, G, Perra, T, Tutino, R, Belia, F, Coletta, D, Belli, A, Rega, D, Cianci, P, Pirozzolo, G, Di Lena, M, Perrone, F, Giani, A, Lovisetto, F, Grassia, M, Pipitone Federico, N, Ferrara, F, Biancafarina, A, Tamini, N, Sinibaldi, G, Tuminello, F, Galleano, R, Sasia, D, Bragaglia, L, de Manzoni Garberini, A, Pesce, A, Cassaro, F, Venturelli, P, Canu, G, Esposito, G, Campanelli, M, Cardia, R, Ricciardiello, M, Sagnotta, A, Canonico, G, De Marco, G, Cappiello, A, Pinotti, E, Carlei, F, Lisi, G, Bagaglini, G, Farrugia, M, Meima-Van Praag, E, Monteiro, C, Pereira, M, Botelho, P, Quigley, A, O'Neill, A, Gaule, L, Crone, L, Arnold, A, Grama, F, Beuca, A, Tulina, I, Litvin, A, Panyko, A, Ossola, M, Trujillo Diaz, J, Marin Santos, J, Alonso Batanero, E, Gortazar de las Casas, S, Soldevila Verdeguer, C, Colas-Ruiz, E, Talal El-Abur, I, Garcia Dominguez, M, Delorme, M, Sauvain, M, Ozmen, B, Ozkan, B, Calikoglu, F, Kural, S, Zafer, F, Kaya, Y, Yalcinkaya, A, Kargici, K, Tepe, M, Tatar, O, Kabadayi, E, Yildirim, A, Hurmuzlu, D, Korkmaz, K, Sharma, P, Troller, R, Hagan, N, Mooney, J, Light, A, Tansey, M, Bhojwani, D, Mcging, R, Mallon, A, Fadel, M, Spilsbury, C, James, R, O'Brien, S, Isaac, A, Balasubramanya, S, Sadik, H, Gala, T, Chen, J, Turner, B, Goh, E, Hassan, K, Karam, M, Mason, P, Tzoumas, N, Noton, T, Seehra, J, Ahmed, N, Motiwale, R, Tanna, V, Argyriou, A, Bylapudi, S, Grace, N, Latif, S, Hounat, A, Kiam, J, Zaidi, M, Elsamani, K, Hughes, C, Suresh, A, Sinan, L, El-Dalil, D, Khoo, E, Salim, E, Stark, D, Minhas, N, Fowler, G, Rees, E, Giudiceandrea, I, Bardon, A, Jayawardena, P, Dieseru, N, Murphy, A, Yates, C, Ziolkowska, K, Rafie, A, Khoda, F, Okocha, M, Ashdown, T, Vitish-Sharma, P, Gilliland, J, Toh, S, Jones, K, Devine, A, Berry, A, Mcdonnell, S, Olivier, J, Richardson, G, Lim, H, Slim, N, Elsayeh, K, Sammour, T, Sarpanov, A, Belev, N, Dimitrov, D, Dusek, T, Ntomi, V, Sotiropoulos, G, Theodorou, D, Nikiteas, N, Balalis, D, Antropoli, C, Altomare, D, Luglio, G, De Palma, G, Pedrazzani, C, Simonelli, L, Brozzetti, S, Porcu, A, Massani, M, Grazi, G, Izzo, F, Delrio, P, Restini, E, Chetta, G, Lantone, G, Ferrari, G, Lucchi, A, De Prizio, M, Caristo, G, Borghi, F, Petrucciani, N, Huscher, C, Cocorullo, G, Tonini, V, Medas, F, Sica, G, Cillara, N, Anastasi, A, Bianco, F, Giuliani, A, Carlini, M, Selvaggi, F, Sammarco, G, Ozolins, A, Malasonoks, A, Andrejevic, P, Tanis, P, van de Ven, A, Gerhards, M, Ribeiro da Silva, B, Silva, A, Lima, M, Kavanagh, D, Mccawley, N, Bintintan, V, Karamarkovic, A, Sanz Ortega, G, De Andres-Asenjo, B, Nevado Garcia, C, Garcia Florez, L, Segura-Sampedro, J, Blas Laina, J, Ponchietti, L, Buchwald, P, Gialamas, E, Ozben, V, Rencuzogullari, A, Gecim, I, Altinel, Y, Isik, O, Yoldas, T, Isik, A, Leventoglu, S, Erturk, M, Guner, A, Guler, S, Attaallah, W, Ugur, M, Ozbalci, G, Marzook, H, Eardley, N, Smolarek, S, Morgan, R, Roxburgh, C, Lala, A, Salama, Y, Singh, B, Khanna, A, Evans, M, Shaikh, I, Maradi Thippeswamy, K, Appleton, B, Moug, S, Smith, I, Smart, N, Shah, P, Williams, G, Khera, G, Goede, A, Varcada, M, Parmar, C, Duff, S, Hargest, R, Marriott, P, Speake, D, Ben Sassi, A, Furfaro, B, Daudu, D, Golijanin, N, Yek, W, Capasso, G, Mansour, L, Niu, N, Seow, W, Hamidovic, A, Kulovic, E, Letic, E, Aljic, A, Helez, M, Banji-Kelan, A, Dimitrova, N, Kavradjieva, P, Ivanov, V, Jukaku, A, Hadzhiev, D, Gabarski, A, Karamanliev, M, Vladova, P, Iliev, S, Yotsov, T, Vetsa, K, Stavrinidou, O, Papatheodorou, P, Liassides, T, Georgiou, T, Al Nassrallah, M, Altaf, R, Negametzyanov, M, Zagibova, D, Foltys, F, Stefanova, H, Paspala, A, Bompetsi, G, Sidiropoulos, T, Stamopoulos, P, Triantafyllou, A, Theodoropoulos, C, Kimpizi, A, Palyvou, T, Charalabopoulos, A, Syllaios, A, Schizas, D, Liatsou, E, Baili, E, Vagios, I, Tomara, N, Davakis, S, Palumbo, A, Foroni, F, Dibra, R, Papagni, V, Urbani, A, Rossin, E, Nezi, G, Romano, P, Amendola, A, Esposito, E, Manigrasso, M, Anoldo, P, Vertaldi, S, Gecchele, G, Sabrina, Z, Guerci, C, Cammarata, F, Lamperti, G, Zaffaroni, G, Benuzzi, L, Ferrario, L, Cigognini, M, Mazzeo, C, Badessi, G, Pintabona, G, Fassari, A, Mingoli, A, Cirillo, B, D'Alterio, C, Brachini, G, Tancredi, M, Zambon, M, Aulicino, M, Sapienza, P, Liberatore, P, Scanu, A, Feo, C, Iacomino, A, Pelizzo, P, Rossi, S, Vigna, S, Grossi, U, Grillo, V, Agnes, A, Schena, C, Marincola, G, Oddi, A, Perotti, B, Mario, V, Perri, P, Zazza, S, Aversano, A, Scala, D, Di Lauro, K, Leongito, M, Piccirillo, M, Patrone, R, Capuzzolo, S, Vignotto, C, Bao, Q, Giuseppe, C, Angarano, E, Marino, F, Pezzolla, F, Gigante, G, Magistro, C, Crippa, J, Maspero, M, Carnevali, P, Trapani, R, Zonta, S, Agostinelli, L, Vittori, L, Romeo, L, Doria, E, Farnesi, F, Danna, R, Andolfi, E, Pellicano', G, Angelini, M, Scricciolo, M, Zanframundo, C, Ciulli, C, Ripamonti, L, Cigagna, L, Oldani, M, Larcinese, A, Rossi, D, Picone, E, Crescentini, G, Marano, A, Migliore, M, Giuffrida, M, Palagi, S, Testa, V, Borrello, A, Lucarini, A, Garofalo, E, Canali, G, Orlandi, P, Nervegna, F, Marchegiani, F, Damoli, I, Licata, A, Trovato, C, Alicata, F, Sardo, F, Milazzo, M, Randisi, B, Dominici, D, Sartarelli, L, Zanni, M, Pisanu, A, Soddu, C, Delogu, D, Erdas, E, Campus, F, Cappellacci, F, Casti, F, Marcialis, J, Atzeni, J, Sensi, B, Franceschilli, M, Bellato, V, Cannavera, A, Putzu, G, di Mola, F, Picardi, B, Solinas, L, Loponte, M, Rossi del Monte, S, Di Martino, C, Linari, C, Spagni, G, Capezzuoli, L, Tirloni, L, Nelli, T, Caridi, A, Elter, C, Camassa, M, D'Amico, S, Bargellini, T, Incollingo, P, Montuori, M, Maffione, F, Romano, L, Valiyeva, S, Spoletini, D, Menegon Tasselli, F, Sciaudone, G, Selvaggi, L, Menna, M, De Paola, G, Fulginiti, S, Truskovs, A, Weiss, C, Saknitis, G, Rauscher, J, Larnovskis, J, Jeyarajan-Davidsson, M, Nitisa, D, Gille, N, Reiser, S, Roshan, M, Leseman, C, van Dalen, A, Top, C, Detering, R, Matos, C, Silva, C, Pinto, D, Mendes, J, Couto, J, Leite, M, Velez, C, Damasio Cotovio, M, Cinza, A, Pedroso de Lima, R, Boyle, E, Yang, H, Banerjee, I, Rahmat, S, Afzal, Z, Reid, C, Dumitrascu, F, Croyle, J, Gressmann, K, Cullen, N, Graham, A, Nasehi, A, Montano King, C, Martin, B, Stokell, C, Sanderson, N, Farnan, R, Jassim, S, Chan, B, Chua Vi Long, K, Kaka, N, Pandey, S, Neo, W, Chitul, A, Bezede, C, Cincilei, D, David, A, Blaga, M, Blaga, S, Fagarasan, V, Khetagurova, M, Rodimov, S, Kapustina, A, Mekhralyzade, A, Zabiyaka, M, Jankovic, U, Cuk, V, Hajska, M, Dubovsky, M, Hrosova, M, Ferancikova, N, Camarero Rodriguez, E, Laguna Alcantara, F, Adarraga, J, Jezieniecki, C, Ruiz Soriano, M, Gomez Sanz, T, Suarez, A, Sanchez Garcia, C, Cifrian Canales, I, Llosa Perez, J, Merayo, M, Urbieta, A, Gegundez Simon, A, Tone, J, Gazo Martinez, J, Vicario Bravo, M, Chavarrias, N, Gil Catalan, A, Oseira, A, Villalonga, B, Jeri, S, Perez Calvo, J, Nogues, A, Cros, B, Yanez, C, Utrilla Fornals, A, Roldon Golet, M, Colsa, P, Gimenez Maurel, T, Axmarker, T, Chevallay, M, Pham, T, Sel, E, Atar, C, Aba, M, Sarkin, M, Akkaya, Y, Durmaz, A, Gullu, H, Boga, A, Aktas, A, Bakar, B, Demirel, M, Hysejni, X, Taser, M, Guzel, O, Bozbiyik, O, Ozen, D, Olmez, M, Uyar, B, Gulcek, E, Kayacan, G, Atici, N, Gul, O, Altiner, S, Ibis, B, Altunsu, S, Banaz, T, Diler, C, Demirbas, I, Usta, M, Erkul, O, Orman, R, Salih, S, Utkan, N, Acil, C, Ozgur, E, Maddahali, M, Turhan, A, Eskici, A, Ular, B, Dogru, M, Ozturk, O, Arslan, E, Panahi Sharif, A, Dikmen, E, Ates, J, Bircan, R, Cavus, T, Sever, A, Balak, B, Duman, E, Altay, L, Emanet, O, Cullen, F, Tan, J, Nathan, A, Rottenberg, A, Williams, C, Mitrofan, C, Xu, D, Bawa, J, Morris, P, Gordon, D, Richmond, G, Hui, J, Ighomereho, O, Rocks, R, Mccabe, S, Fitzpatrick, A, Nicoletti, J, Auterson, L, Darrah, N, Soh, V, Ong, C, Utukuri, M, Gallagher, C, Stuart, L, Hipolito, M, Douglas, N, Ghazal, R, Parris, G, Catchpole, J, Bryden, M, Jamal, S, Karim, Z, Lyon-Dean, C, Rowley, G, Lee, K, Whitehurst, O, Mirza, A, Sheikh, F, Yousaf, H, Bilbao, J, Sinclair, R, Takar, S, Kressel, H, Chan, V, Schack, K, Osborne, R, Baldemor, S, Smyth, S, Gilmour, S, Ting, A, Bozonelou, I, Saunders, P, Qhaireel Anwar, Q, Tirimanna, R, Jauhari, S, Gardener, A, Walker, B, Wenban, C, Reddy, H, Conway-Jones, R, Loganathan, S, Clynch, A, James, C, Matey, E, Cameron, F, Roberts, W, Gicquel, A, Milliken, C, Forbes, J, Rubinchik, P, Azmi, A, Hawkes, C, Cornett, L, Adarkwah, P, Mcconville, R, O'Hara, S, Tijare, C, Parkes, J, Yao, L, Ahmad, R, Shafiq, U, Mhaisalkar, A, Gurung, A, de Stadler, K, Elias, S, Thomas, T, Madras, A, Jani, A, Daler, H, Tong, K, Sundaralingam, S, Szal, A, Khan, A, O'Sullivan, C, Baker, E, Joseph-Gubral, J, Hadley, E, Trivedi, R, Igwelaezoh, E, Barton, H, Allison, W, Hurst, W, Alam, F, Parkes, I, Jamshaid, M, Azizan, N, Burgher, T, Afzal, A, Eltilib, I, Zahid, M, Sadiq, O, Lloyd, A, Ho, R, Brazukas, A, Li, C, Kamdar, M, Mohamed Nazeer, M, Mighiu, A, Kim, D, Wilkins, L, Kuo, L, Rafe, T, Maduka, D, Cheema, H, Farag, K, Abdellatif, M, Nzewi, R, Kruczynska, A, Grasselli, H, Yousuff, M, Bassi, R, Mann, A, Chopra, J, Shaikh, M, Sa, D, Tsimplis, V, Ghanchi, A, Skene, E, Asim, K, Zaheer, M, Chan, S, Dalton, H, Gibbons, K, Adderley, O, Chukwujindu, I, Jayasuriya, I, Sivanu, K, Borumand, M, Chick, G, Bridges, I, Tomlin, J, Mckenna, J, Nandra, N, Grieco, C, Quek, F, Mercer, R, Brankin-Frisby, T, Sattar, A, Aslam, A, Edelsten, E, Shafi, S, Kouli, T, Ford, V, Gurung, F, Fernandes, M, Deader, N, Ponniah, R, Jamieson, S, Davies, A, Taubwurcel, J, Aung, M, Desai, R, Begum, S, Jamadar, T, Kangatharan, A, Rzeszowski, B, Ho, C, Yap, S, Prendergast, M, Sethi, R, Duku, A, Lowe, C, Bray, J, Ghobrial, M, Nichita, V, Wagstaff, A, Rengasamy, E, Abu Hassan, F, Mahmood, H, Savill, N, Shah, S, Almeida, T, Edwards, A, Catchpole, B, Halford, Z, Carmichael, A, Alsusa, H, Boyd, M, Williams, J, Feyi-Waboso, J, Patel, M, Zeidan, Z, Bailey, E, Bapty, J, Brazkiewicz, M, Tremlett, A, Pringle, H, Mankal, S, Chung, W, Parry-Jones, E, Anderson, K, Mcforrester, A, Stanley, A, Hoather, A, Wise, H, Laid, I, Scriven, J, Braniste, A, Wilson, A, Le Blevec, L, Pakunwanich, N, Evans, N, Chong, H, White, C, Hunter, J, Haque, M, Vanalia, P, Murdoch, S, Choudhary, T, Mccann, A, Harun, A, Shah, H, Hunt, S, Shafiq, Y, Bickley-Morris, E, Emms, L, Dare, M, Akula, Y, Deliyannis, E, Mayes, F, Ellacott, M, Zagorac, Z, Farren, A, Manning, C, Hughed, C, Stewart, E, Lim, K, Chohan, N, Thaker, A, Thompson, B, Ahari, D, Burdekin, E, Okwu, U, Akintunde, A, Lhaf, F, Douthwaite, J, Govindan, R, Leelamanthep, S, Gull, E, Wright, F, Dundas, L, Mackdermott, N, Burchi-Khairy, T, Campbell, I, Walsh, J, Yeo, J, Meehan, S, Banerjee, D, Fu, M, Kawka, M, Ali, T, Hussain, Z, Thomas, C, Ahmad, H, Moroney, J, Yick, C, Risquet, R, Ntuiabane, D, Shimato, M, Khan, M, Ilangovan, S, Vaselli, N, Smithers, R, Uhanowita Marage, R, Valnarov-Boulter, A, Kayran, J, Banerjee, M, Parekh-Hill, N, Hooper, A, Bowen, J, Jagdish, R, Mcquoid, C, Khan, N, O'Hare, R, Jeffery, S, Zahid, A, Elsworth, C, Walter, L, Dhillon, S, Rao, S, Anthony, A, Ashaye, A, Phillips, N, Faderani, R, Pengelly, S, Choi, S, Kwak, S, Lau, Y, Bagheri, K, Ong, D, Kerr, E, Falconer, K, Clancy, N, Douglas, S, Zhang, Y, Greenfield, F, Mutanga, I, Mcalinden, J, Willis, L, Adefolaju, A, Agarwal, H, Barter, R, Harris, G, Spencer, G, Lee, M, Vadiveloo, V, Herbert, G, Patel, R, Shah, M, El Falaha, S, Wong, C, Soare, C, Akram, J, Bozhkova, L, Ma, Y, Vo, U, Tan, H, Leto, L, Kamal, M, Hadzhieva, E, Krastev, P, Tonchev, P, Kokkinos, G, Pozotou, I, Sabbagh, D, Votava, J, St, F, Koliakos, N, Tsaparas, P, Zografos, G, Mantas, D, Tsourouflis, G, Fradelos, E, Trigiante, G, Labellarte, G, Resta, G, Capelli, G, D'Amore, A, Verlingieri, V, Campagnaro, T, Maffioli, A, Viscosi, F, De Lucia, C, Meneghini, S, Fancellu, A, Colella, M, Biondi, A, De Peppo, V, Pace, U, Albino, V, Gattulli, D, Piangerelli, A, Kalivaci, D, Sisto, G, Mazzola, M, Caneparo, A, Lunghi, E, Nespoli, L, Angrisani, M, Langone, A, Gelarda, E, Virgilio, E, Angelini, E, Fornasier, C, Asero, S, Filippone, E, Frongia, F, Calo, P, Panaccio, P, Ipponi, P, Gili, S, Braccio, B, Tiesi, V, Stolcers, K, Kokaine, L, Novikovs, V, Capel, L, Bastiaenen, V, Heijmans, H, Henriques, S, Gan, S, Ramanayake, H, Nolan, M, Temperley, H, Ciofic, E, Pop, B, Kurtenkov, M, Jovanovic, M, Vician, M, Egea Arias, P, Beltran de Heredia, J, Labalde Martinez, M, De Santiago Alvarez, I, Alvarez-Gallego, M, Rodriguez Artigas, J, Dwidar, O, Korkmaz, H, Eray, I, Meric, S, Aydin, R, Cetin, B, Karaca, B, Kuyumcu, O, Yuksel, E, Uprak, T, Karabulut, K, Kavukcu, E, Mansor, A, Hackett, R, Zammit-Maempel, M, Sabaratnam, R, Maan, A, Ferarrio, I, Dixon, L, Halai, H, Sethi, S, Nelson, L, Grassam-Rowe, A, Krishnan, E, Deeny, D, Mckeever, M, George Pandeth, A, Dhavala, P, Sreenivasan, S, Sundaram Venkatesan, G, Zhu, L, Atiyah, Z, Gregory, J, Morey, T, Seymour, Z, Holdsworth, L, Abdelmahmoud, S, Bourhill, J, Bisheet, G, Shaw, J, Kulkarni, K, Kumarakulasingam, P, Pillay, S, Al-Habsi, R, Kungwengwe, G, Richards, J, Davoudi, K, Ibrahim, B, Tailor, B, Zayed, M, Chen, F, Bailey, S, Sheefat, S, Nawaz, G, Pawar, R, Marsh, S, Sam, Z, Roy Bentley, S, Simpson, C, Lim, Y, Ooi, R, Toh, W, Mannion, P, Lovett, A, Kincius, A, Hussein, S, Kirby, E, Beckett, R, Salmon, J, Glynn, T, Choo, S, Lyons, S, Browne, D, Ravindran, W, Ahmad, S, Zhu, X, Mcnulty, J, Mccarthy, L, Ng, J, Karmally, Z, Mcteir, K, Hanna, M, Tan, E, Namdeo, S, Schembri, R, Pusey, E, Sgro A., Blanco-Colino R., Ahmed W. U. R., Brindl N., Gujjuri R. R., Lapolla P., Mills E. C., Perez-Ajates S., Soares A. S., Varghese C., Xu W., McLean K. A., Chapman S. J., Espin-Basany E., Glasbey J. C., Mihaljevic A., Nepogodiev D., Pata F., Pellino G., Pockney P., Dudi-Venkata N. N., Egoroff N., Ludbrook I., Raubenheimer K., Richards T., Delibegovic S., Salibasic M., Amjad T., Dorr-Harim C., Gedeon N., Gsenger J., Tachezy M., Bini S., Gallo G., Gori A., Picciariello A., Podda M., Riboni C., Machatschek M. J., Nguyen A., Jakubauskas M., Kryzauskas M., Poskus T., Kuiper S. Z., Wang J., Wells C. I., Bissett I. P., Augestad K. M., Steinholt I., Vieira B. N., Juloski J., Anabitarte Bautista O., El Kasmy El Kasmy Y., Martin-Borregon P., Ossola Revilla M., Van Straten S., Aktas M. K., Baki B. E., Akhbari M., Baker D., Bhatia S., Brown S., Cambridge W., Kamarajah S. K., Khaw R. A., Kouli O., Murray V., Trout I., Yasin I., Wong J. Y., Reyhani H., Wong K. H. F., Pancharatnam R., Chia W. L., Walmsley A., Hassane A., Saeed D., Wang B., Walters B., Nowinka Z., Alsaif A., Mirza M., Foster K., Luu J., Kakodkar P., Hughes J. T., Yogarajah T., Antypas A., Rahman A., Bradbury M., McLarnon M., Nagi S., Riad A. M., Erotocritou M., Kyriacou H., Kaminskaite V., Alfadhel S., Fatimah Hussain Q., Handa A., Massy-Westropp C., Custovic S., Dimov R., Mughal H., Slavchev M., Ivanov T., Gouvas N., Hegazi A., Kocian P., Kjaer M. D., Mark-Christensen A., Papakonstantinou D., Machairas N., Triantafyllou T., Garoufalia Z., Korkolis D., Castaldi A., Giaccari S., Spolverato G., Pagano G., Milone M., Turri G., Colombo F., Cucinotta E., Poillucci G., Perra T., Tutino R., Belia F., Coletta D., Belli A., Rega D., Cianci P., Pirozzolo G., Di Lena M., Perrone F., Giani A., Lovisetto F., Grassia M., Pipitone Federico N. S., Ferrara F., Biancafarina A., Tamini N., Sinibaldi G., Tuminello F., Galleano R., Sasia D., Bragaglia L., de Manzoni Garberini A., Pesce A., Cassaro F., Venturelli P., Canu G. L., Esposito G., Campanelli M., Cardia R., Ricciardiello M., Sagnotta A., Canonico G., De Marco G., Cappiello A., Pinotti E., Carlei F., Lisi G., Bagaglini G., Farrugia M., Meima-Van Praag E. M., Monteiro C., Pereira M., Botelho P., Quigley A., O'Neill A., Gaule L., Crone L., Arnold A., Grama F., Beuca A., Tulina I., Litvin A., Panyko A., Ossola M. E., Trujillo Diaz J., Marin Santos J. M., Alonso Batanero E., Gortazar de las Casas S., Soldevila Verdeguer C., Colas-Ruiz E., Talal El-Abur I., Garcia Dominguez M., Delorme M., Sauvain M., Ozmen B. B., Ozkan B. B., Calikoglu F., Kural S., Zafer F., Kaya Y., Yalcinkaya A., Kargici K., Tepe M. D., Tatar O. C., Kabadayi E., Yildirim A., Hurmuzlu D., Korkmaz K., Sharma P., Troller R., Hagan N., Mooney J., Light A., Tansey M., Bhojwani D., McGing R. M., Mallon A., Fadel M., Spilsbury C., James R., O'Brien S., Isaac A., Balasubramanya S., Sadik H., Gala T., Chen J. Y., Turner B., Goh E., Hassan K., Karam M., Mason P., Tzoumas N., Noton T., Seehra J. K., Ahmed N., Motiwale R., Tanna V., Argyriou A., Bylapudi S. K., Grace N., Latif S., Hounat A., Kiam J. S., Zaidi M., Elsamani K., Hughes C., Suresh A., Sinan L. O. H., El-Dalil D., Khoo E. J. M., Salim E. E., Stark D., Minhas N., Fowler G., Rees E., Giudiceandrea I., Bardon A., Jayawardena P., Dieseru N., Murphy A., Yates C., Ziolkowska K., Rafie A., Khoda F., Okocha M., Ashdown T., Vitish-Sharma P., Gilliland J., Toh S., Jones K., Devine A., Berry A., McDonnell S., Olivier J., Richardson G., Lim H. J., Slim N., Elsayeh K., Sammour T., Sarpanov A., Belev N., Dimitrov D., Dusek T., Ntomi V., Sotiropoulos G. C., Theodorou D., Nikiteas N., Balalis D., Antropoli C., Altomare D. F., Luglio G., De Palma G. D., Pedrazzani C., Simonelli L., Brozzetti S., Porcu A., Massani M., Grazi G. L., Izzo F., Delrio P., Restini E., Chetta G., Lantone G., Ferrari G., Lucchi A., De Prizio M., Caristo G., Borghi F., Petrucciani N., Huscher C., Cocorullo G., Tonini V., Medas F., Sica G., Cillara N., Anastasi A., Bianco F., Giuliani A., Carlini M., Selvaggi F., Sammarco G., Ozolins A., Malasonoks A., Andrejevic P., Tanis P., van de Ven A., Gerhards M., Ribeiro da Silva B., Silva A., Lima M. J., Kavanagh D., McCawley N., Bintintan V., Karamarkovic A., Sanz Ortega G., De Andres-Asenjo B., Nevado Garcia C., Garcia Florez L. J., Segura-Sampedro J. J., Blas Laina J. L., Ponchietti L., Buchwald P., Gialamas E., Ozben V., Rencuzogullari A., Gecim I. E., Altinel Y., Isik O., Yoldas T., Isik A., Leventoglu S., Erturk M. S., Guner A., Guler S. A., Attaallah W., Ugur M., Ozbalci G. S., Marzook H., Eardley N., Smolarek S., Morgan R., Roxburgh C., Lala A. K., Salama Y., Singh B., Khanna A., Evans M., Shaikh I., Maradi Thippeswamy K., Appleton B., Moug S., Smith I., Smart N., Shah P., Williams G., Khera G., Goede A., Varcada M., Parmar C., Duff S., Hargest R., Marriott P., Speake D., Ben Sassi A., Furfaro B., Daudu D., Golijanin N., Yek W. Y., Capasso G., Mansour L. T., Niu N., Seow W., Hamidovic A., Kulovic E., Letic E., Aljic A., Helez M., Banji-Kelan A., Dimitrova N., Kavradjieva P., Ivanov V., Jukaku A., Hadzhiev D., Gabarski A., Karamanliev M., Vladova P., Iliev S., Yotsov T., Vetsa K., Stavrinidou O., Papatheodorou P., Liassides T., Georgiou T., Al Nassrallah M., Altaf R., Negametzyanov M., Zagibova D., Foltys F., Stefanova H., Paspala A., Bompetsi G., Sidiropoulos T., Stamopoulos P., Triantafyllou A., Theodoropoulos C., Kimpizi A., Palyvou T., Charalabopoulos A., Syllaios A., Schizas D., Liatsou E., Baili E., Vagios I., Tomara N., Davakis S., Palumbo A., Foroni F., Dibra R., Papagni V., Urbani A., Rossin E., Nezi G., Romano P., Amendola A., Esposito E., Manigrasso M., Anoldo P., Vertaldi S., Gecchele G., Sabrina Z. S., Guerci C., Cammarata F., Lamperti G. M. B., Zaffaroni G., Benuzzi L., Ferrario L., Cigognini M., Mazzeo C., Badessi G., Pintabona G., Fassari A., Mingoli A., Cirillo B., D'Alterio C., Brachini G., Tancredi M., Zambon M., Aulicino M., Sapienza P., Liberatore P., Scanu A. M., Feo C. F., Iacomino A., Pelizzo P., Rossi S., Vigna S. A., Grossi U., Grillo V., Agnes A., Schena C. A., Marincola G., Oddi A., Perotti B., Mario V., Perri P., Zazza S., Aversano A., Scala D., Di Lauro K., Leongito M., Piccirillo M., Patrone R., Capuzzolo S., Vignotto C., Bao Q. R., Giuseppe C., Angarano E., Marino F., Pezzolla F., Gigante G., Magistro C., Crippa J., Maspero M., Carnevali P., Trapani R., Zonta S., Agostinelli L., Vittori L., Romeo L., Doria E., Farnesi F., Danna R., Andolfi E., Pellicano' G. A., Angelini M., Scricciolo M., Zanframundo C., Ciulli C., Ripamonti L., Cigagna L., Oldani M., Larcinese A., Rossi D., Picone E., Crescentini G., Marano A., Migliore M., Giuffrida M. C., Palagi S., Testa V., Borrello A., Lucarini A., Garofalo E., Canali G., Orlandi P., Nervegna F., Marchegiani F., Damoli I., Licata A., Trovato C., Alicata F., Sardo F., Milazzo M., Randisi B., Dominici D. M., Sartarelli L., Zanni M., Pisanu A., Soddu C., Delogu D., Erdas E., Campus F., Cappellacci F., Casti F., Marcialis J., Atzeni J., Podda M. G., Sensi B., Franceschilli M., Bellato V., Cannavera A., Putzu G., di Mola F. F., Picardi B., Solinas L., Loponte M., Rossi del Monte S., Di Martino C., Linari C., Spagni G., Capezzuoli L., Tirloni L., Nelli T., Caridi A., Elter C., Camassa M., D'Amico S., Bargellini T., Incollingo P., Montuori M., Maffione F., Romano L., Valiyeva S., Spoletini D., Menegon Tasselli F., Sciaudone G., Selvaggi L., Menna M. P., De Paola G., Fulginiti S., Truskovs A., Weiss C., Saknitis G., Rauscher J. T. R., Larnovskis J., Jeyarajan-Davidsson M., Nitisa D., Gille N., Reiser S. C., Roshan M. H. K., Leseman C., Chen J., van Dalen A. S., Top C., Detering R., Matos C., Silva C., Pinto D., Mendes J., Couto J., Leite M., Velez C., Damasio Cotovio M., Cinza A. M., Pedroso de Lima R., Boyle E., Yang H. W., Banerjee I., Rahmat S., Afzal Z., Reid C., Dumitrascu F., Croyle J. A., Gressmann K., Cullen N., Graham A., Nasehi A., Montano King C., Martin B., Stokell C., Sanderson N., Farnan R., Jassim S., Chan B., Chua Vi Long K., Kaka N., Pandey S., Neo W. X., Chitul A., Bezede C., Cincilei D., David A., Blaga M., Blaga S. N., Fagarasan V., Khetagurova M., Rodimov S., Kapustina A., Mekhralyzade A., Zabiyaka M., Jankovic U., Cuk V., Hajska M., Dubovsky M., Hrosova M., Ferancikova N., Camarero Rodriguez E., Laguna Alcantara F., Adarraga J., Jezieniecki C., Ruiz Soriano M., Gomez Sanz T., Suarez A., Sanchez Garcia C., Cifrian Canales I., Llosa Perez J., Merayo M., Urbieta A., Gegundez Simon A., Tone J. F., Gazo Martinez J., Vicario Bravo M., Chavarrias N., Gil Catalan A., Oseira A., Villalonga B., Jeri S., Perez Calvo J., Nogues A., Cros B., Yanez C., Utrilla Fornals A., Roldon Golet M., Colsa P., Gimenez Maurel T., Axmarker T., Chevallay M., Pham T. V., Sel E. K., Atar C., Aba M., Sarkin M., Akkaya Y. M., Durmaz A. G., Gullu H. F., Boga A., Aktas A., Bakar B., Demirel M. T., Hysejni X., Taser M., Guzel O. R., Bozbiyik O., Ozen D., Olmez M., Uyar B., Gulcek E., Kayacan G. S., Atici N., Gul O. F., Altiner S., Ibis B., Altunsu S., Banaz T., Diler C., Demirbas I., Usta M. A., Erkul O., Orman R., Salih S., Utkan N. Z., Acil C., Ozgur E., Maddahali M., Turhan A. B., Eskici A. B., Ular B., Dogru M., Ozturk O. U., Arslan E. R., Panahi Sharif A., Dikmen E., Ates J., Bircan R., Cavus T., Sever A. E., Balak B., Duman E., Altay L., Emanet O., Cullen F., Tan J. Y., Nathan A., Rottenberg A., Williams C. Y., Mitrofan C. G., Xu D., Bawa J. H., Morris P., Gordon D., Richmond G., Hui J. C., Ighomereho O., Rocks R., McCabe S., Fitzpatrick A., Nicoletti J., Auterson L., Darrah N., Soh V. W. Y., Ong C. S., Utukuri M., Gallagher C., Stuart L. M., Hipolito M., Douglas N., Ghazal R., Parris G., Catchpole J., Bryden M., Jamal S., Karim Z., Lyon-Dean C., Rowley G., Lee K. S., Whitehurst O., Mirza A., Sheikh F., Yousaf H., Bilbao J., Sinclair R., Takar S., Kressel H., Chan V., Schack K., Osborne R., Baldemor S., Smyth S., Gilmour S., Ting A., Bozonelou I., Saunders P., Qhaireel Anwar Q. A., Tirimanna R., Jauhari S., Gardener A., Walker B., Wenban C., Reddy H., Conway-Jones R., Loganathan S., Clynch A., James C., Matey E., Cameron F., Roberts W., Gicquel A., Milliken C., Forbes J., Rubinchik P., Azmi A., Hawkes C., Cornett L., Adarkwah P., McConville R., O'Hara S., Tijare C., Parkes J., Yao L., Ahmad R., Shafiq U., Mhaisalkar A., Gurung A., de Stadler K., Elias S., Thomas T., Madras A., Jani A., Daler H. K., Tong K. S., Sundaralingam S. S., Szal A., Khan A., O'Sullivan C., Baker E., Joseph-Gubral J., Hadley E., Trivedi R., Igwelaezoh E., Barton H., Allison W., Hurst W., Alam F., Parkes I., Jamshaid M., Azizan N., Burgher T., Afzal A., Eltilib I., Zahid M., Sadiq O., Lloyd A., Ho R., Brazukas A., Li C. H., Kamdar M., Mohamed Nazeer M. N., Mighiu A., Kim D., Wilkins L., Kuo L., Rafe T., Maduka D., Cheema H., Farag K., Abdellatif M., Nzewi R., Kruczynska A., Grasselli H., Yousuff M., Bassi R., Mann A. K., Chopra J., Shaikh M., Sa D. S., Tsimplis V., Ghanchi A., Skene E., Asim K., Zaheer M., Chan S., Dalton H., Gibbons K., Adderley O., Chukwujindu I., Jayasuriya I., Sivanu K., Borumand M., Chick G., Bridges I., Tomlin J., McKenna J., Nandra N., Grieco C., Quek F. F., Mercer R., Brankin-Frisby T., Sattar A., Aslam A., Edelsten E., Shafi S., Kouli T., Ford V., Gurung F., Fernandes M., Deader N., Ponniah R., Jamieson S., Davies A., Taubwurcel J., Aung M. T., Desai R., Begum S., Jamadar T., Kangatharan A., Rzeszowski B., Ho C., Yap S. H. K., Prendergast M., Sethi R., Duku A., Lowe C., Bray J., Ghobrial M., Nichita V., Wagstaff A., Rengasamy E., Abu Hassan F., Mahmood H., Savill N., Shah S., Almeida T., Edwards A., Catchpole B., Halford Z., Carmichael A., Alsusa H., Boyd M., Williams J., Feyi-Waboso J., Patel M., Zeidan Z., Bailey E., Bapty J., Brazkiewicz M., Tremlett A., Pringle H., Mankal S., Chung W., Parry-Jones E., Anderson K., McForrester A., Stanley A., Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H. L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E. G., Lim K. H., Chohan N., Thaker A., Thompson B., Ahari D., Burdekin E., Okwu U., Akintunde A., Lhaf F., Douthwaite J., Govindan R., Leelamanthep S., Gull E., Wright F., Dundas L., Mackdermott N., Burchi-Khairy T., Campbell I., Walsh J., Yeo J. Y., Meehan S., Banerjee D., Fu M., Kawka M., Ali T., Hussain Z., Thomas C., Ahmad H., Moroney J., Yick C., Risquet R., Ntuiabane D., Shimato M., Khan M., Ilangovan S., Vaselli N. M., Smithers R., Uhanowita Marage R., Valnarov-Boulter A., Kayran J., Banerjee M., Parekh-Hill N., Hooper A., Bowen J., Jagdish R., McQuoid C., Khan N., O'Hare R., Jeffery S., Zahid A., Elsworth C., Walter L., Dhillon S., Rao S., Anthony A., Ashaye A., Phillips N., Faderani R., Pengelly S., Choi S., Kwak S. Y., Lau Y. H. L., Bagheri K., Ong D. Y. C., Kerr E., Falconer K., Clancy N., Douglas S., Zhang Y., Greenfield F., Mutanga I., McAlinden J., Willis L., Adefolaju A., Agarwal H., Barter R., Harris G., Spencer G., Lee M. W., Vadiveloo V. T., Herbert G., Patel R., Shah M., El Falaha S., Wong C., Soare C., Akram J., Bozhkova L., Ma Y., Vo U. G., Tan H. W. N., Leto L., Kamal M. A., Hadzhieva E., Krastev P., Tonchev P., Kokkinos G., Pozotou I., Sabbagh D., Votava J., St F., Koliakos N., Tsaparas P., Zografos G., Mantas D., Tsourouflis G., Fradelos E., Trigiante G., Labellarte G., Resta G., Capelli G., D'Amore A., Verlingieri V., Campagnaro T., Maffioli A., Viscosi F., De Lucia C., Meneghini S., Fancellu A., Colella M., Biondi A., De Peppo V., Pace U., Albino V., Gattulli D., Piangerelli A., Kalivaci D., Sisto G., Mazzola M., Caneparo A., Lunghi E. G., Nespoli L. C., Angrisani M., Langone A., Gelarda E., Virgilio E., Angelini E., Fornasier C., Asero S., Filippone E., Frongia F., Calo P. G., Panaccio P., Ipponi P., Gili S., Braccio B., Tiesi V., Stolcers K., Kokaine L., Novikovs V., Capel L., Bastiaenen V., Heijmans H., Henriques S., Gan S. Z., Ramanayake H., Nolan M., Temperley H., Ciofic E., Pop B. A., Kurtenkov M., Jovanovic M., Vician M., Egea Arias P., Beltran de Heredia J., Labalde Martinez M., De Santiago Alvarez I., Alvarez-Gallego M., Rodriguez Artigas J. M., Dwidar O., Korkmaz H. K., Eray I. C., Meric S., Aydin R., Cetin B., Karaca B. E., Kuyumcu O. F., Yuksel E., Uprak T. K., Karabulut K., Kavukcu E., Mansor A., Hackett R., Zammit-Maempel M., Sabaratnam R., Maan A., Ferarrio I., Dixon L., Halai H., Sethi S., Nelson L., Grassam-Rowe A., Krishnan E., Deeny D., McKeever M., George Pandeth A., Dhavala P., Sreenivasan S., Sundaram Venkatesan G., Zhu L., Atiyah Z., Gregory J., Morey T., Seymour Z., Holdsworth L., Abdelmahmoud S., Bourhill J., Bisheet G., Shaw J., Kulkarni K., Kumarakulasingam P., Pillay S., Al-Habsi R., Kungwengwe G., Richards J., Davoudi K., Ibrahim B., Tailor B., Zayed M., Chen F., Bailey S., Sheefat S., Nawaz G., Pawar R., Marsh S., Sam Z. H., Roy Bentley S., Simpson C., Hughes J., Lim Y., Ooi R., Toh W. H., Mannion P., Lovett A., Kincius A., Hussein S., Kirby E., Beckett R. G., Salmon J., Glynn T., Choo S. Y., Lyons S., Browne D., Ravindran W., Ahmad S., Zhu X., McNulty J., McCarthy L., Ng J., Karmally Z., McTeir K., Hanna M., Tan E., Namdeo S., Schembri R., Pusey E., Sgro, A, Blanco-Colino, R, Ahmed, W, Brindl, N, Gujjuri, R, Lapolla, P, Mills, E, Perez-Ajates, S, Soares, A, Varghese, C, Xu, W, Mclean, K, Chapman, S, Espin-Basany, E, Glasbey, J, Mihaljevic, A, Nepogodiev, D, Pata, F, Pellino, G, Pockney, P, Dudi-Venkata, N, Egoroff, N, Ludbrook, I, Raubenheimer, K, Richards, T, Delibegovic, S, Salibasic, M, Amjad, T, Dorr-Harim, C, Gedeon, N, Gsenger, J, Tachezy, M, Bini, S, Gallo, G, Gori, A, Picciariello, A, Podda, M, Riboni, C, Machatschek, M, Nguyen, A, Jakubauskas, M, Kryzauskas, M, Poskus, T, Kuiper, S, Wang, J, Wells, C, Bissett, I, Augestad, K, Steinholt, I, Vieira, B, Juloski, J, Anabitarte Bautista, O, El Kasmy El Kasmy, Y, Martin-Borregon, P, Ossola Revilla, M, Van Straten, S, Aktas, M, Baki, B, Akhbari, M, Baker, D, Bhatia, S, Brown, S, Cambridge, W, Kamarajah, S, Khaw, R, Kouli, O, Murray, V, Trout, I, Yasin, I, Wong, J, Reyhani, H, Wong, K, Pancharatnam, R, Chia, W, Walmsley, A, Hassane, A, Saeed, D, Wang, B, Walters, B, Nowinka, Z, Alsaif, A, Mirza, M, Foster, K, Luu, J, Kakodkar, P, Hughes, J, Yogarajah, T, Antypas, A, Rahman, A, Bradbury, M, Mclarnon, M, Nagi, S, Riad, A, Erotocritou, M, Kyriacou, H, Kaminskaite, V, Alfadhel, S, Fatimah Hussain, Q, Handa, A, Massy-Westropp, C, Custovic, S, Dimov, R, Mughal, H, Slavchev, M, Ivanov, T, Gouvas, N, Hegazi, A, Kocian, P, Kjaer, M, Mark-Christensen, A, Papakonstantinou, D, Machairas, N, Triantafyllou, T, Garoufalia, Z, Korkolis, D, Castaldi, A, Giaccari, S, Spolverato, G, Pagano, G, Milone, M, Turri, G, Colombo, F, Cucinotta, E, Poillucci, G, Perra, T, Tutino, R, Belia, F, Coletta, D, Belli, A, Rega, D, Cianci, P, Pirozzolo, G, Di Lena, M, Perrone, F, Giani, A, Lovisetto, F, Grassia, M, Pipitone Federico, N, Ferrara, F, Biancafarina, A, Tamini, N, Sinibaldi, G, Tuminello, F, Galleano, R, Sasia, D, Bragaglia, L, de Manzoni Garberini, A, Pesce, A, Cassaro, F, Venturelli, P, Canu, G, Esposito, G, Campanelli, M, Cardia, R, Ricciardiello, M, Sagnotta, A, Canonico, G, De Marco, G, Cappiello, A, Pinotti, E, Carlei, F, Lisi, G, Bagaglini, G, Farrugia, M, Meima-Van Praag, E, Monteiro, C, Pereira, M, Botelho, P, Quigley, A, O'Neill, A, Gaule, L, Crone, L, Arnold, A, Grama, F, Beuca, A, Tulina, I, Litvin, A, Panyko, A, Ossola, M, Trujillo Diaz, J, Marin Santos, J, Alonso Batanero, E, Gortazar de las Casas, S, Soldevila Verdeguer, C, Colas-Ruiz, E, Talal El-Abur, I, Garcia Dominguez, M, Delorme, M, Sauvain, M, Ozmen, B, Ozkan, B, Calikoglu, F, Kural, S, Zafer, F, Kaya, Y, Yalcinkaya, A, Kargici, K, Tepe, M, Tatar, O, Kabadayi, E, Yildirim, A, Hurmuzlu, D, Korkmaz, K, Sharma, P, Troller, R, Hagan, N, Mooney, J, Light, A, Tansey, M, Bhojwani, D, Mcging, R, Mallon, A, Fadel, M, Spilsbury, C, James, R, O'Brien, S, Isaac, A, Balasubramanya, S, Sadik, H, Gala, T, Chen, J, Turner, B, Goh, E, Hassan, K, Karam, M, Mason, P, Tzoumas, N, Noton, T, Seehra, J, Ahmed, N, Motiwale, R, Tanna, V, Argyriou, A, Bylapudi, S, Grace, N, Latif, S, Hounat, A, Kiam, J, Zaidi, M, Elsamani, K, Hughes, C, Suresh, A, Sinan, L, El-Dalil, D, Khoo, E, Salim, E, Stark, D, Minhas, N, Fowler, G, Rees, E, Giudiceandrea, I, Bardon, A, Jayawardena, P, Dieseru, N, Murphy, A, Yates, C, Ziolkowska, K, Rafie, A, Khoda, F, Okocha, M, Ashdown, T, Vitish-Sharma, P, Gilliland, J, Toh, S, Jones, K, Devine, A, Berry, A, Mcdonnell, S, Olivier, J, Richardson, G, Lim, H, Slim, N, Elsayeh, K, Sammour, T, Sarpanov, A, Belev, N, Dimitrov, D, Dusek, T, Ntomi, V, Sotiropoulos, G, Theodorou, D, Nikiteas, N, Balalis, D, Antropoli, C, Altomare, D, Luglio, G, De Palma, G, Pedrazzani, C, Simonelli, L, Brozzetti, S, Porcu, A, Massani, M, Grazi, G, Izzo, F, Delrio, P, Restini, E, Chetta, G, Lantone, G, Ferrari, G, Lucchi, A, De Prizio, M, Caristo, G, Borghi, F, Petrucciani, N, Huscher, C, Cocorullo, G, Tonini, V, Medas, F, Sica, G, Cillara, N, Anastasi, A, Bianco, F, Giuliani, A, Carlini, M, Selvaggi, F, Sammarco, G, Ozolins, A, Malasonoks, A, Andrejevic, P, Tanis, P, van de Ven, A, Gerhards, M, Ribeiro da Silva, B, Silva, A, Lima, M, Kavanagh, D, Mccawley, N, Bintintan, V, Karamarkovic, A, Sanz Ortega, G, De Andres-Asenjo, B, Nevado Garcia, C, Garcia Florez, L, Segura-Sampedro, J, Blas Laina, J, Ponchietti, L, Buchwald, P, Gialamas, E, Ozben, V, Rencuzogullari, A, Gecim, I, Altinel, Y, Isik, O, Yoldas, T, Isik, A, Leventoglu, S, Erturk, M, Guner, A, Guler, S, Attaallah, W, Ugur, M, Ozbalci, G, Marzook, H, Eardley, N, Smolarek, S, Morgan, R, Roxburgh, C, Lala, A, Salama, Y, Singh, B, Khanna, A, Evans, M, Shaikh, I, Maradi Thippeswamy, K, Appleton, B, Moug, S, Smith, I, Smart, N, Shah, P, Williams, G, Khera, G, Goede, A, Varcada, M, Parmar, C, Duff, S, Hargest, R, Marriott, P, Speake, D, Ben Sassi, A, Furfaro, B, Daudu, D, Golijanin, N, Yek, W, Capasso, G, Mansour, L, Niu, N, Seow, W, Hamidovic, A, Kulovic, E, Letic, E, Aljic, A, Helez, M, Banji-Kelan, A, Dimitrova, N, Kavradjieva, P, Ivanov, V, Jukaku, A, Hadzhiev, D, Gabarski, A, Karamanliev, M, Vladova, P, Iliev, S, Yotsov, T, Vetsa, K, Stavrinidou, O, Papatheodorou, P, Liassides, T, Georgiou, T, Al Nassrallah, M, Altaf, R, Negametzyanov, M, Zagibova, D, Foltys, F, Stefanova, H, Paspala, A, Bompetsi, G, Sidiropoulos, T, Stamopoulos, P, Triantafyllou, A, Theodoropoulos, C, Kimpizi, A, Palyvou, T, Charalabopoulos, A, Syllaios, A, Schizas, D, Liatsou, E, Baili, E, Vagios, I, Tomara, N, Davakis, S, Palumbo, A, Foroni, F, Dibra, R, Papagni, V, Urbani, A, Rossin, E, Nezi, G, Romano, P, Amendola, A, Esposito, E, Manigrasso, M, Anoldo, P, Vertaldi, S, Gecchele, G, Sabrina, Z, Guerci, C, Cammarata, F, Lamperti, G, Zaffaroni, G, Benuzzi, L, Ferrario, L, Cigognini, M, Mazzeo, C, Badessi, G, Pintabona, G, Fassari, A, Mingoli, A, Cirillo, B, D'Alterio, C, Brachini, G, Tancredi, M, Zambon, M, Aulicino, M, Sapienza, P, Liberatore, P, Scanu, A, Feo, C, Iacomino, A, Pelizzo, P, Rossi, S, Vigna, S, Grossi, U, Grillo, V, Agnes, A, Schena, C, Marincola, G, Oddi, A, Perotti, B, Mario, V, Perri, P, Zazza, S, Aversano, A, Scala, D, Di Lauro, K, Leongito, M, Piccirillo, M, Patrone, R, Capuzzolo, S, Vignotto, C, Bao, Q, Giuseppe, C, Angarano, E, Marino, F, Pezzolla, F, Gigante, G, Magistro, C, Crippa, J, Maspero, M, Carnevali, P, Trapani, R, Zonta, S, Agostinelli, L, Vittori, L, Romeo, L, Doria, E, Farnesi, F, Danna, R, Andolfi, E, Pellicano', G, Angelini, M, Scricciolo, M, Zanframundo, C, Ciulli, C, Ripamonti, L, Cigagna, L, Oldani, M, Larcinese, A, Rossi, D, Picone, E, Crescentini, G, Marano, A, Migliore, M, Giuffrida, M, Palagi, S, Testa, V, Borrello, A, Lucarini, A, Garofalo, E, Canali, G, Orlandi, P, Nervegna, F, Marchegiani, F, Damoli, I, Licata, A, Trovato, C, Alicata, F, Sardo, F, Milazzo, M, Randisi, B, Dominici, D, Sartarelli, L, Zanni, M, Pisanu, A, Soddu, C, Delogu, D, Erdas, E, Campus, F, Cappellacci, F, Casti, F, Marcialis, J, Atzeni, J, Sensi, B, Franceschilli, M, Bellato, V, Cannavera, A, Putzu, G, di Mola, F, Picardi, B, Solinas, L, Loponte, M, Rossi del Monte, S, Di Martino, C, Linari, C, Spagni, G, Capezzuoli, L, Tirloni, L, Nelli, T, Caridi, A, Elter, C, Camassa, M, D'Amico, S, Bargellini, T, Incollingo, P, Montuori, M, Maffione, F, Romano, L, Valiyeva, S, Spoletini, D, Menegon Tasselli, F, Sciaudone, G, Selvaggi, L, Menna, M, De Paola, G, Fulginiti, S, Truskovs, A, Weiss, C, Saknitis, G, Rauscher, J, Larnovskis, J, Jeyarajan-Davidsson, M, Nitisa, D, Gille, N, Reiser, S, Roshan, M, Leseman, C, van Dalen, A, Top, C, Detering, R, Matos, C, Silva, C, Pinto, D, Mendes, J, Couto, J, Leite, M, Velez, C, Damasio Cotovio, M, Cinza, A, Pedroso de Lima, R, Boyle, E, Yang, H, Banerjee, I, Rahmat, S, Afzal, Z, Reid, C, Dumitrascu, F, Croyle, J, Gressmann, K, Cullen, N, Graham, A, Nasehi, A, Montano King, C, Martin, B, Stokell, C, Sanderson, N, Farnan, R, Jassim, S, Chan, B, Chua Vi Long, K, Kaka, N, Pandey, S, Neo, W, Chitul, A, Bezede, C, Cincilei, D, David, A, Blaga, M, Blaga, S, Fagarasan, V, Khetagurova, M, Rodimov, S, Kapustina, A, Mekhralyzade, A, Zabiyaka, M, Jankovic, U, Cuk, V, Hajska, M, Dubovsky, M, Hrosova, M, Ferancikova, N, Camarero Rodriguez, E, Laguna Alcantara, F, Adarraga, J, Jezieniecki, C, Ruiz Soriano, M, Gomez Sanz, T, Suarez, A, Sanchez Garcia, C, Cifrian Canales, I, Llosa Perez, J, Merayo, M, Urbieta, A, Gegundez Simon, A, Tone, J, Gazo Martinez, J, Vicario Bravo, M, Chavarrias, N, Gil Catalan, A, Oseira, A, Villalonga, B, Jeri, S, Perez Calvo, J, Nogues, A, Cros, B, Yanez, C, Utrilla Fornals, A, Roldon Golet, M, Colsa, P, Gimenez Maurel, T, Axmarker, T, Chevallay, M, Pham, T, Sel, E, Atar, C, Aba, M, Sarkin, M, Akkaya, Y, Durmaz, A, Gullu, H, Boga, A, Aktas, A, Bakar, B, Demirel, M, Hysejni, X, Taser, M, Guzel, O, Bozbiyik, O, Ozen, D, Olmez, M, Uyar, B, Gulcek, E, Kayacan, G, Atici, N, Gul, O, Altiner, S, Ibis, B, Altunsu, S, Banaz, T, Diler, C, Demirbas, I, Usta, M, Erkul, O, Orman, R, Salih, S, Utkan, N, Acil, C, Ozgur, E, Maddahali, M, Turhan, A, Eskici, A, Ular, B, Dogru, M, Ozturk, O, Arslan, E, Panahi Sharif, A, Dikmen, E, Ates, J, Bircan, R, Cavus, T, Sever, A, Balak, B, Duman, E, Altay, L, Emanet, O, Cullen, F, Tan, J, Nathan, A, Rottenberg, A, Williams, C, Mitrofan, C, Xu, D, Bawa, J, Morris, P, Gordon, D, Richmond, G, Hui, J, Ighomereho, O, Rocks, R, Mccabe, S, Fitzpatrick, A, Nicoletti, J, Auterson, L, Darrah, N, Soh, V, Ong, C, Utukuri, M, Gallagher, C, Stuart, L, Hipolito, M, Douglas, N, Ghazal, R, Parris, G, Catchpole, J, Bryden, M, Jamal, S, Karim, Z, Lyon-Dean, C, Rowley, G, Lee, K, Whitehurst, O, Mirza, A, Sheikh, F, Yousaf, H, Bilbao, J, Sinclair, R, Takar, S, Kressel, H, Chan, V, Schack, K, Osborne, R, Baldemor, S, Smyth, S, Gilmour, S, Ting, A, Bozonelou, I, Saunders, P, Qhaireel Anwar, Q, Tirimanna, R, Jauhari, S, Gardener, A, Walker, B, Wenban, C, Reddy, H, Conway-Jones, R, Loganathan, S, Clynch, A, James, C, Matey, E, Cameron, F, Roberts, W, Gicquel, A, Milliken, C, Forbes, J, Rubinchik, P, Azmi, A, Hawkes, C, Cornett, L, Adarkwah, P, Mcconville, R, O'Hara, S, Tijare, C, Parkes, J, Yao, L, Ahmad, R, Shafiq, U, Mhaisalkar, A, Gurung, A, de Stadler, K, Elias, S, Thomas, T, Madras, A, Jani, A, Daler, H, Tong, K, Sundaralingam, S, Szal, A, Khan, A, O'Sullivan, C, Baker, E, Joseph-Gubral, J, Hadley, E, Trivedi, R, Igwelaezoh, E, Barton, H, Allison, W, Hurst, W, Alam, F, Parkes, I, Jamshaid, M, Azizan, N, Burgher, T, Afzal, A, Eltilib, I, Zahid, M, Sadiq, O, Lloyd, A, Ho, R, Brazukas, A, Li, C, Kamdar, M, Mohamed Nazeer, M, Mighiu, A, Kim, D, Wilkins, L, Kuo, L, Rafe, T, Maduka, D, Cheema, H, Farag, K, Abdellatif, M, Nzewi, R, Kruczynska, A, Grasselli, H, Yousuff, M, Bassi, R, Mann, A, Chopra, J, Shaikh, M, Sa, D, Tsimplis, V, Ghanchi, A, Skene, E, Asim, K, Zaheer, M, Chan, S, Dalton, H, Gibbons, K, Adderley, O, Chukwujindu, I, Jayasuriya, I, Sivanu, K, Borumand, M, Chick, G, Bridges, I, Tomlin, J, Mckenna, J, Nandra, N, Grieco, C, Quek, F, Mercer, R, Brankin-Frisby, T, Sattar, A, Aslam, A, Edelsten, E, Shafi, S, Kouli, T, Ford, V, Gurung, F, Fernandes, M, Deader, N, Ponniah, R, Jamieson, S, Davies, A, Taubwurcel, J, Aung, M, Desai, R, Begum, S, Jamadar, T, Kangatharan, A, Rzeszowski, B, Ho, C, Yap, S, Prendergast, M, Sethi, R, Duku, A, Lowe, C, Bray, J, Ghobrial, M, Nichita, V, Wagstaff, A, Rengasamy, E, Abu Hassan, F, Mahmood, H, Savill, N, Shah, S, Almeida, T, Edwards, A, Catchpole, B, Halford, Z, Carmichael, A, Alsusa, H, Boyd, M, Williams, J, Feyi-Waboso, J, Patel, M, Zeidan, Z, Bailey, E, Bapty, J, Brazkiewicz, M, Tremlett, A, Pringle, H, Mankal, S, Chung, W, Parry-Jones, E, Anderson, K, Mcforrester, A, Stanley, A, Hoather, A, Wise, H, Laid, I, Scriven, J, Braniste, A, Wilson, A, Le Blevec, L, Pakunwanich, N, Evans, N, Chong, H, White, C, Hunter, J, Haque, M, Vanalia, P, Murdoch, S, Choudhary, T, Mccann, A, Harun, A, Shah, H, Hunt, S, Shafiq, Y, Bickley-Morris, E, Emms, L, Dare, M, Akula, Y, Deliyannis, E, Mayes, F, Ellacott, M, Zagorac, Z, Farren, A, Manning, C, Hughed, C, Stewart, E, Lim, K, Chohan, N, Thaker, A, Thompson, B, Ahari, D, Burdekin, E, Okwu, U, Akintunde, A, Lhaf, F, Douthwaite, J, Govindan, R, Leelamanthep, S, Gull, E, Wright, F, Dundas, L, Mackdermott, N, Burchi-Khairy, T, Campbell, I, Walsh, J, Yeo, J, Meehan, S, Banerjee, D, Fu, M, Kawka, M, Ali, T, Hussain, Z, Thomas, C, Ahmad, H, Moroney, J, Yick, C, Risquet, R, Ntuiabane, D, Shimato, M, Khan, M, Ilangovan, S, Vaselli, N, Smithers, R, Uhanowita Marage, R, Valnarov-Boulter, A, Kayran, J, Banerjee, M, Parekh-Hill, N, Hooper, A, Bowen, J, Jagdish, R, Mcquoid, C, Khan, N, O'Hare, R, Jeffery, S, Zahid, A, Elsworth, C, Walter, L, Dhillon, S, Rao, S, Anthony, A, Ashaye, A, Phillips, N, Faderani, R, Pengelly, S, Choi, S, Kwak, S, Lau, Y, Bagheri, K, Ong, D, Kerr, E, Falconer, K, Clancy, N, Douglas, S, Zhang, Y, Greenfield, F, Mutanga, I, Mcalinden, J, Willis, L, Adefolaju, A, Agarwal, H, Barter, R, Harris, G, Spencer, G, Lee, M, Vadiveloo, V, Herbert, G, Patel, R, Shah, M, El Falaha, S, Wong, C, Soare, C, Akram, J, Bozhkova, L, Ma, Y, Vo, U, Tan, H, Leto, L, Kamal, M, Hadzhieva, E, Krastev, P, Tonchev, P, Kokkinos, G, Pozotou, I, Sabbagh, D, Votava, J, St, F, Koliakos, N, Tsaparas, P, Zografos, G, Mantas, D, Tsourouflis, G, Fradelos, E, Trigiante, G, Labellarte, G, Resta, G, Capelli, G, D'Amore, A, Verlingieri, V, Campagnaro, T, Maffioli, A, Viscosi, F, De Lucia, C, Meneghini, S, Fancellu, A, Colella, M, Biondi, A, De Peppo, V, Pace, U, Albino, V, Gattulli, D, Piangerelli, A, Kalivaci, D, Sisto, G, Mazzola, M, Caneparo, A, Lunghi, E, Nespoli, L, Angrisani, M, Langone, A, Gelarda, E, Virgilio, E, Angelini, E, Fornasier, C, Asero, S, Filippone, E, Frongia, F, Calo, P, Panaccio, P, Ipponi, P, Gili, S, Braccio, B, Tiesi, V, Stolcers, K, Kokaine, L, Novikovs, V, Capel, L, Bastiaenen, V, Heijmans, H, Henriques, S, Gan, S, Ramanayake, H, Nolan, M, Temperley, H, Ciofic, E, Pop, B, Kurtenkov, M, Jovanovic, M, Vician, M, Egea Arias, P, Beltran de Heredia, J, Labalde Martinez, M, De Santiago Alvarez, I, Alvarez-Gallego, M, Rodriguez Artigas, J, Dwidar, O, Korkmaz, H, Eray, I, Meric, S, Aydin, R, Cetin, B, Karaca, B, Kuyumcu, O, Yuksel, E, Uprak, T, Karabulut, K, Kavukcu, E, Mansor, A, Hackett, R, Zammit-Maempel, M, Sabaratnam, R, Maan, A, Ferarrio, I, Dixon, L, Halai, H, Sethi, S, Nelson, L, Grassam-Rowe, A, Krishnan, E, Deeny, D, Mckeever, M, George Pandeth, A, Dhavala, P, Sreenivasan, S, Sundaram Venkatesan, G, Zhu, L, Atiyah, Z, Gregory, J, Morey, T, Seymour, Z, Holdsworth, L, Abdelmahmoud, S, Bourhill, J, Bisheet, G, Shaw, J, Kulkarni, K, Kumarakulasingam, P, Pillay, S, Al-Habsi, R, Kungwengwe, G, Richards, J, Davoudi, K, Ibrahim, B, Tailor, B, Zayed, M, Chen, F, Bailey, S, Sheefat, S, Nawaz, G, Pawar, R, Marsh, S, Sam, Z, Roy Bentley, S, Simpson, C, Lim, Y, Ooi, R, Toh, W, Mannion, P, Lovett, A, Kincius, A, Hussein, S, Kirby, E, Beckett, R, Salmon, J, Glynn, T, Choo, S, Lyons, S, Browne, D, Ravindran, W, Ahmad, S, Zhu, X, Mcnulty, J, Mccarthy, L, Ng, J, Karmally, Z, Mcteir, K, Hanna, M, Tan, E, Namdeo, S, Schembri, R, Pusey, E, Sgro A., Blanco-Colino R., Ahmed W. U. R., Brindl N., Gujjuri R. R., Lapolla P., Mills E. C., Perez-Ajates S., Soares A. S., Varghese C., Xu W., McLean K. A., Chapman S. J., Espin-Basany E., Glasbey J. C., Mihaljevic A., Nepogodiev D., Pata F., Pellino G., Pockney P., Dudi-Venkata N. N., Egoroff N., Ludbrook I., Raubenheimer K., Richards T., Delibegovic S., Salibasic M., Amjad T., Dorr-Harim C., Gedeon N., Gsenger J., Tachezy M., Bini S., Gallo G., Gori A., Picciariello A., Podda M., Riboni C., Machatschek M. J., Nguyen A., Jakubauskas M., Kryzauskas M., Poskus T., Kuiper S. Z., Wang J., Wells C. I., Bissett I. P., Augestad K. M., Steinholt I., Vieira B. N., Juloski J., Anabitarte Bautista O., El Kasmy El Kasmy Y., Martin-Borregon P., Ossola Revilla M., Van Straten S., Aktas M. K., Baki B. E., Akhbari M., Baker D., Bhatia S., Brown S., Cambridge W., Kamarajah S. K., Khaw R. A., Kouli O., Murray V., Trout I., Yasin I., Wong J. Y., Reyhani H., Wong K. H. F., Pancharatnam R., Chia W. L., Walmsley A., Hassane A., Saeed D., Wang B., Walters B., Nowinka Z., Alsaif A., Mirza M., Foster K., Luu J., Kakodkar P., Hughes J. T., Yogarajah T., Antypas A., Rahman A., Bradbury M., McLarnon M., Nagi S., Riad A. M., Erotocritou M., Kyriacou H., Kaminskaite V., Alfadhel S., Fatimah Hussain Q., Handa A., Massy-Westropp C., Custovic S., Dimov R., Mughal H., Slavchev M., Ivanov T., Gouvas N., Hegazi A., Kocian P., Kjaer M. D., Mark-Christensen A., Papakonstantinou D., Machairas N., Triantafyllou T., Garoufalia Z., Korkolis D., Castaldi A., Giaccari S., Spolverato G., Pagano G., Milone M., Turri G., Colombo F., Cucinotta E., Poillucci G., Perra T., Tutino R., Belia F., Coletta D., Belli A., Rega D., Cianci P., Pirozzolo G., Di Lena M., Perrone F., Giani A., Lovisetto F., Grassia M., Pipitone Federico N. S., Ferrara F., Biancafarina A., Tamini N., Sinibaldi G., Tuminello F., Galleano R., Sasia D., Bragaglia L., de Manzoni Garberini A., Pesce A., Cassaro F., Venturelli P., Canu G. L., Esposito G., Campanelli M., Cardia R., Ricciardiello M., Sagnotta A., Canonico G., De Marco G., Cappiello A., Pinotti E., Carlei F., Lisi G., Bagaglini G., Farrugia M., Meima-Van Praag E. M., Monteiro C., Pereira M., Botelho P., Quigley A., O'Neill A., Gaule L., Crone L., Arnold A., Grama F., Beuca A., Tulina I., Litvin A., Panyko A., Ossola M. E., Trujillo Diaz J., Marin Santos J. M., Alonso Batanero E., Gortazar de las Casas S., Soldevila Verdeguer C., Colas-Ruiz E., Talal El-Abur I., Garcia Dominguez M., Delorme M., Sauvain M., Ozmen B. B., Ozkan B. B., Calikoglu F., Kural S., Zafer F., Kaya Y., Yalcinkaya A., Kargici K., Tepe M. D., Tatar O. C., Kabadayi E., Yildirim A., Hurmuzlu D., Korkmaz K., Sharma P., Troller R., Hagan N., Mooney J., Light A., Tansey M., Bhojwani D., McGing R. M., Mallon A., Fadel M., Spilsbury C., James R., O'Brien S., Isaac A., Balasubramanya S., Sadik H., Gala T., Chen J. Y., Turner B., Goh E., Hassan K., Karam M., Mason P., Tzoumas N., Noton T., Seehra J. K., Ahmed N., Motiwale R., Tanna V., Argyriou A., Bylapudi S. K., Grace N., Latif S., Hounat A., Kiam J. S., Zaidi M., Elsamani K., Hughes C., Suresh A., Sinan L. O. H., El-Dalil D., Khoo E. J. M., Salim E. E., Stark D., Minhas N., Fowler G., Rees E., Giudiceandrea I., Bardon A., Jayawardena P., Dieseru N., Murphy A., Yates C., Ziolkowska K., Rafie A., Khoda F., Okocha M., Ashdown T., Vitish-Sharma P., Gilliland J., Toh S., Jones K., Devine A., Berry A., McDonnell S., Olivier J., Richardson G., Lim H. J., Slim N., Elsayeh K., Sammour T., Sarpanov A., Belev N., Dimitrov D., Dusek T., Ntomi V., Sotiropoulos G. C., Theodorou D., Nikiteas N., Balalis D., Antropoli C., Altomare D. F., Luglio G., De Palma G. D., Pedrazzani C., Simonelli L., Brozzetti S., Porcu A., Massani M., Grazi G. L., Izzo F., Delrio P., Restini E., Chetta G., Lantone G., Ferrari G., Lucchi A., De Prizio M., Caristo G., Borghi F., Petrucciani N., Huscher C., Cocorullo G., Tonini V., Medas F., Sica G., Cillara N., Anastasi A., Bianco F., Giuliani A., Carlini M., Selvaggi F., Sammarco G., Ozolins A., Malasonoks A., Andrejevic P., Tanis P., van de Ven A., Gerhards M., Ribeiro da Silva B., Silva A., Lima M. J., Kavanagh D., McCawley N., Bintintan V., Karamarkovic A., Sanz Ortega G., De Andres-Asenjo B., Nevado Garcia C., Garcia Florez L. J., Segura-Sampedro J. J., Blas Laina J. L., Ponchietti L., Buchwald P., Gialamas E., Ozben V., Rencuzogullari A., Gecim I. E., Altinel Y., Isik O., Yoldas T., Isik A., Leventoglu S., Erturk M. S., Guner A., Guler S. A., Attaallah W., Ugur M., Ozbalci G. S., Marzook H., Eardley N., Smolarek S., Morgan R., Roxburgh C., Lala A. K., Salama Y., Singh B., Khanna A., Evans M., Shaikh I., Maradi Thippeswamy K., Appleton B., Moug S., Smith I., Smart N., Shah P., Williams G., Khera G., Goede A., Varcada M., Parmar C., Duff S., Hargest R., Marriott P., Speake D., Ben Sassi A., Furfaro B., Daudu D., Golijanin N., Yek W. Y., Capasso G., Mansour L. T., Niu N., Seow W., Hamidovic A., Kulovic E., Letic E., Aljic A., Helez M., Banji-Kelan A., Dimitrova N., Kavradjieva P., Ivanov V., Jukaku A., Hadzhiev D., Gabarski A., Karamanliev M., Vladova P., Iliev S., Yotsov T., Vetsa K., Stavrinidou O., Papatheodorou P., Liassides T., Georgiou T., Al Nassrallah M., Altaf R., Negametzyanov M., Zagibova D., Foltys F., Stefanova H., Paspala A., Bompetsi G., Sidiropoulos T., Stamopoulos P., Triantafyllou A., Theodoropoulos C., Kimpizi A., Palyvou T., Charalabopoulos A., Syllaios A., Schizas D., Liatsou E., Baili E., Vagios I., Tomara N., Davakis S., Palumbo A., Foroni F., Dibra R., Papagni V., Urbani A., Rossin E., Nezi G., Romano P., Amendola A., Esposito E., Manigrasso M., Anoldo P., Vertaldi S., Gecchele G., Sabrina Z. S., Guerci C., Cammarata F., Lamperti G. M. B., Zaffaroni G., Benuzzi L., Ferrario L., Cigognini M., Mazzeo C., Badessi G., Pintabona G., Fassari A., Mingoli A., Cirillo B., D'Alterio C., Brachini G., Tancredi M., Zambon M., Aulicino M., Sapienza P., Liberatore P., Scanu A. M., Feo C. F., Iacomino A., Pelizzo P., Rossi S., Vigna S. A., Grossi U., Grillo V., Agnes A., Schena C. A., Marincola G., Oddi A., Perotti B., Mario V., Perri P., Zazza S., Aversano A., Scala D., Di Lauro K., Leongito M., Piccirillo M., Patrone R., Capuzzolo S., Vignotto C., Bao Q. R., Giuseppe C., Angarano E., Marino F., Pezzolla F., Gigante G., Magistro C., Crippa J., Maspero M., Carnevali P., Trapani R., Zonta S., Agostinelli L., Vittori L., Romeo L., Doria E., Farnesi F., Danna R., Andolfi E., Pellicano' G. A., Angelini M., Scricciolo M., Zanframundo C., Ciulli C., Ripamonti L., Cigagna L., Oldani M., Larcinese A., Rossi D., Picone E., Crescentini G., Marano A., Migliore M., Giuffrida M. C., Palagi S., Testa V., Borrello A., Lucarini A., Garofalo E., Canali G., Orlandi P., Nervegna F., Marchegiani F., Damoli I., Licata A., Trovato C., Alicata F., Sardo F., Milazzo M., Randisi B., Dominici D. M., Sartarelli L., Zanni M., Pisanu A., Soddu C., Delogu D., Erdas E., Campus F., Cappellacci F., Casti F., Marcialis J., Atzeni J., Podda M. G., Sensi B., Franceschilli M., Bellato V., Cannavera A., Putzu G., di Mola F. F., Picardi B., Solinas L., Loponte M., Rossi del Monte S., Di Martino C., Linari C., Spagni G., Capezzuoli L., Tirloni L., Nelli T., Caridi A., Elter C., Camassa M., D'Amico S., Bargellini T., Incollingo P., Montuori M., Maffione F., Romano L., Valiyeva S., Spoletini D., Menegon Tasselli F., Sciaudone G., Selvaggi L., Menna M. P., De Paola G., Fulginiti S., Truskovs A., Weiss C., Saknitis G., Rauscher J. T. R., Larnovskis J., Jeyarajan-Davidsson M., Nitisa D., Gille N., Reiser S. C., Roshan M. H. K., Leseman C., Chen J., van Dalen A. S., Top C., Detering R., Matos C., Silva C., Pinto D., Mendes J., Couto J., Leite M., Velez C., Damasio Cotovio M., Cinza A. M., Pedroso de Lima R., Boyle E., Yang H. W., Banerjee I., Rahmat S., Afzal Z., Reid C., Dumitrascu F., Croyle J. A., Gressmann K., Cullen N., Graham A., Nasehi A., Montano King C., Martin B., Stokell C., Sanderson N., Farnan R., Jassim S., Chan B., Chua Vi Long K., Kaka N., Pandey S., Neo W. X., Chitul A., Bezede C., Cincilei D., David A., Blaga M., Blaga S. N., Fagarasan V., Khetagurova M., Rodimov S., Kapustina A., Mekhralyzade A., Zabiyaka M., Jankovic U., Cuk V., Hajska M., Dubovsky M., Hrosova M., Ferancikova N., Camarero Rodriguez E., Laguna Alcantara F., Adarraga J., Jezieniecki C., Ruiz Soriano M., Gomez Sanz T., Suarez A., Sanchez Garcia C., Cifrian Canales I., Llosa Perez J., Merayo M., Urbieta A., Gegundez Simon A., Tone J. F., Gazo Martinez J., Vicario Bravo M., Chavarrias N., Gil Catalan A., Oseira A., Villalonga B., Jeri S., Perez Calvo J., Nogues A., Cros B., Yanez C., Utrilla Fornals A., Roldon Golet M., Colsa P., Gimenez Maurel T., Axmarker T., Chevallay M., Pham T. V., Sel E. K., Atar C., Aba M., Sarkin M., Akkaya Y. M., Durmaz A. G., Gullu H. F., Boga A., Aktas A., Bakar B., Demirel M. T., Hysejni X., Taser M., Guzel O. R., Bozbiyik O., Ozen D., Olmez M., Uyar B., Gulcek E., Kayacan G. S., Atici N., Gul O. F., Altiner S., Ibis B., Altunsu S., Banaz T., Diler C., Demirbas I., Usta M. A., Erkul O., Orman R., Salih S., Utkan N. Z., Acil C., Ozgur E., Maddahali M., Turhan A. B., Eskici A. B., Ular B., Dogru M., Ozturk O. U., Arslan E. R., Panahi Sharif A., Dikmen E., Ates J., Bircan R., Cavus T., Sever A. E., Balak B., Duman E., Altay L., Emanet O., Cullen F., Tan J. Y., Nathan A., Rottenberg A., Williams C. Y., Mitrofan C. G., Xu D., Bawa J. H., Morris P., Gordon D., Richmond G., Hui J. C., Ighomereho O., Rocks R., McCabe S., Fitzpatrick A., Nicoletti J., Auterson L., Darrah N., Soh V. W. Y., Ong C. S., Utukuri M., Gallagher C., Stuart L. M., Hipolito M., Douglas N., Ghazal R., Parris G., Catchpole J., Bryden M., Jamal S., Karim Z., Lyon-Dean C., Rowley G., Lee K. S., Whitehurst O., Mirza A., Sheikh F., Yousaf H., Bilbao J., Sinclair R., Takar S., Kressel H., Chan V., Schack K., Osborne R., Baldemor S., Smyth S., Gilmour S., Ting A., Bozonelou I., Saunders P., Qhaireel Anwar Q. A., Tirimanna R., Jauhari S., Gardener A., Walker B., Wenban C., Reddy H., Conway-Jones R., Loganathan S., Clynch A., James C., Matey E., Cameron F., Roberts W., Gicquel A., Milliken C., Forbes J., Rubinchik P., Azmi A., Hawkes C., Cornett L., Adarkwah P., McConville R., O'Hara S., Tijare C., Parkes J., Yao L., Ahmad R., Shafiq U., Mhaisalkar A., Gurung A., de Stadler K., Elias S., Thomas T., Madras A., Jani A., Daler H. K., Tong K. S., Sundaralingam S. S., Szal A., Khan A., O'Sullivan C., Baker E., Joseph-Gubral J., Hadley E., Trivedi R., Igwelaezoh E., Barton H., Allison W., Hurst W., Alam F., Parkes I., Jamshaid M., Azizan N., Burgher T., Afzal A., Eltilib I., Zahid M., Sadiq O., Lloyd A., Ho R., Brazukas A., Li C. H., Kamdar M., Mohamed Nazeer M. N., Mighiu A., Kim D., Wilkins L., Kuo L., Rafe T., Maduka D., Cheema H., Farag K., Abdellatif M., Nzewi R., Kruczynska A., Grasselli H., Yousuff M., Bassi R., Mann A. K., Chopra J., Shaikh M., Sa D. S., Tsimplis V., Ghanchi A., Skene E., Asim K., Zaheer M., Chan S., Dalton H., Gibbons K., Adderley O., Chukwujindu I., Jayasuriya I., Sivanu K., Borumand M., Chick G., Bridges I., Tomlin J., McKenna J., Nandra N., Grieco C., Quek F. F., Mercer R., Brankin-Frisby T., Sattar A., Aslam A., Edelsten E., Shafi S., Kouli T., Ford V., Gurung F., Fernandes M., Deader N., Ponniah R., Jamieson S., Davies A., Taubwurcel J., Aung M. T., Desai R., Begum S., Jamadar T., Kangatharan A., Rzeszowski B., Ho C., Yap S. H. K., Prendergast M., Sethi R., Duku A., Lowe C., Bray J., Ghobrial M., Nichita V., Wagstaff A., Rengasamy E., Abu Hassan F., Mahmood H., Savill N., Shah S., Almeida T., Edwards A., Catchpole B., Halford Z., Carmichael A., Alsusa H., Boyd M., Williams J., Feyi-Waboso J., Patel M., Zeidan Z., Bailey E., Bapty J., Brazkiewicz M., Tremlett A., Pringle H., Mankal S., Chung W., Parry-Jones E., Anderson K., McForrester A., Stanley A., Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H. L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E. G., Lim K. H., Chohan N., Thaker A., Thompson B., Ahari D., Burdekin E., Okwu U., Akintunde A., Lhaf F., Douthwaite J., Govindan R., Leelamanthep S., Gull E., Wright F., Dundas L., Mackdermott N., Burchi-Khairy T., Campbell I., Walsh J., Yeo J. Y., Meehan S., Banerjee D., Fu M., Kawka M., Ali T., Hussain Z., Thomas C., Ahmad H., Moroney J., Yick C., Risquet R., Ntuiabane D., Shimato M., Khan M., Ilangovan S., Vaselli N. M., Smithers R., Uhanowita Marage R., Valnarov-Boulter A., Kayran J., Banerjee M., Parekh-Hill N., Hooper A., Bowen J., Jagdish R., McQuoid C., Khan N., O'Hare R., Jeffery S., Zahid A., Elsworth C., Walter L., Dhillon S., Rao S., Anthony A., Ashaye A., Phillips N., Faderani R., Pengelly S., Choi S., Kwak S. Y., Lau Y. H. L., Bagheri K., Ong D. Y. C., Kerr E., Falconer K., Clancy N., Douglas S., Zhang Y., Greenfield F., Mutanga I., McAlinden J., Willis L., Adefolaju A., Agarwal H., Barter R., Harris G., Spencer G., Lee M. W., Vadiveloo V. T., Herbert G., Patel R., Shah M., El Falaha S., Wong C., Soare C., Akram J., Bozhkova L., Ma Y., Vo U. G., Tan H. W. N., Leto L., Kamal M. A., Hadzhieva E., Krastev P., Tonchev P., Kokkinos G., Pozotou I., Sabbagh D., Votava J., St F., Koliakos N., Tsaparas P., Zografos G., Mantas D., Tsourouflis G., Fradelos E., Trigiante G., Labellarte G., Resta G., Capelli G., D'Amore A., Verlingieri V., Campagnaro T., Maffioli A., Viscosi F., De Lucia C., Meneghini S., Fancellu A., Colella M., Biondi A., De Peppo V., Pace U., Albino V., Gattulli D., Piangerelli A., Kalivaci D., Sisto G., Mazzola M., Caneparo A., Lunghi E. G., Nespoli L. C., Angrisani M., Langone A., Gelarda E., Virgilio E., Angelini E., Fornasier C., Asero S., Filippone E., Frongia F., Calo P. G., Panaccio P., Ipponi P., Gili S., Braccio B., Tiesi V., Stolcers K., Kokaine L., Novikovs V., Capel L., Bastiaenen V., Heijmans H., Henriques S., Gan S. Z., Ramanayake H., Nolan M., Temperley H., Ciofic E., Pop B. A., Kurtenkov M., Jovanovic M., Vician M., Egea Arias P., Beltran de Heredia J., Labalde Martinez M., De Santiago Alvarez I., Alvarez-Gallego M., Rodriguez Artigas J. M., Dwidar O., Korkmaz H. K., Eray I. C., Meric S., Aydin R., Cetin B., Karaca B. E., Kuyumcu O. F., Yuksel E., Uprak T. K., Karabulut K., Kavukcu E., Mansor A., Hackett R., Zammit-Maempel M., Sabaratnam R., Maan A., Ferarrio I., Dixon L., Halai H., Sethi S., Nelson L., Grassam-Rowe A., Krishnan E., Deeny D., McKeever M., George Pandeth A., Dhavala P., Sreenivasan S., Sundaram Venkatesan G., Zhu L., Atiyah Z., Gregory J., Morey T., Seymour Z., Holdsworth L., Abdelmahmoud S., Bourhill J., Bisheet G., Shaw J., Kulkarni K., Kumarakulasingam P., Pillay S., Al-Habsi R., Kungwengwe G., Richards J., Davoudi K., Ibrahim B., Tailor B., Zayed M., Chen F., Bailey S., Sheefat S., Nawaz G., Pawar R., Marsh S., Sam Z. H., Roy Bentley S., Simpson C., Hughes J., Lim Y., Ooi R., Toh W. H., Mannion P., Lovett A., Kincius A., Hussein S., Kirby E., Beckett R. G., Salmon J., Glynn T., Choo S. Y., Lyons S., Browne D., Ravindran W., Ahmad S., Zhu X., McNulty J., McCarthy L., Ng J., Karmally Z., McTeir K., Hanna M., Tan E., Namdeo S., Schembri R., and Pusey E.
- Abstract
Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of S
- Published
- 2022
5. Intraperitoneal drain placement and outcomes after elective colorectal surgery: International matched, prospective, cohort study
- Author
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Sgro A., Blanco-Colino R., Ahmed W. U. R., Brindl N., Gujjuri R. R., Lapolla P., Mills E. C., Perez-Ajates S., Soares A. S., Varghese C., Xu W., McLean K. A., Chapman S. J., Espin-Basany E., Glasbey J. C., Mihaljevic A., Nepogodiev D., Pata F., Pellino G., Pockney P., Dudi-Venkata N. N., Egoroff N., Ludbrook I., Raubenheimer K., Richards T., Delibegovic S., Salibasic M., Amjad T., Dorr-Harim C., Gedeon N., Gsenger J., Tachezy M., Bini S., Gallo G., Gori A., Picciariello A., Podda M., Riboni C., Machatschek M. J., Nguyen A., Jakubauskas M., Kryzauskas M., Poskus T., Kuiper S. Z., Wang J., Wells C. I., Bissett I. P., Augestad K. M., Steinholt I., Vieira B. N., Juloski J., Anabitarte Bautista O., El Kasmy El Kasmy Y., Martin-Borregon P., Ossola Revilla M., Van Straten S., Aktas M. K., Baki B. E., Akhbari M., Baker D., Bhatia S., Brown S., Cambridge W., Kamarajah S. K., Khaw R. A., Kouli O., Murray V., Trout I., Yasin I., Wong J. Y., Reyhani H., Wong K. H. F., Pancharatnam R., Chia W. L., Walmsley A., Hassane A., Saeed D., Wang B., Walters B., Nowinka Z., Alsaif A., Mirza M., Foster K., Luu J., Kakodkar P., Hughes J. T., Yogarajah T., Antypas A., Rahman A., Bradbury M., McLarnon M., Nagi S., Riad A. M., Erotocritou M., Kyriacou H., Kaminskaite V., Alfadhel S., Fatimah Hussain Q., Handa A., Massy-Westropp C., Custovic S., Dimov R., Mughal H., Slavchev M., Ivanov T., Gouvas N., Hegazi A., Kocian P., Kjaer M. D., Mark-Christensen A., Papakonstantinou D., Machairas N., Triantafyllou T., Garoufalia Z., Korkolis D., Castaldi A., Giaccari S., Spolverato G., Pagano G., Milone M., Turri G., Colombo F., Cucinotta E., Poillucci G., Perra T., Tutino R., Belia F., Coletta D., Belli A., Rega D., Cianci P., Pirozzolo G., Di Lena M., Perrone F., Giani A., Lovisetto F., Grassia M., Pipitone Federico N. S., Ferrara F., Biancafarina A., Tamini N., Sinibaldi G., Tuminello F., Galleano R., Sasia D., Bragaglia L., de Manzoni Garberini A., Pesce A., Cassaro F., Venturelli P., Canu G. L., Esposito G., Campanelli M., Cardia R., Ricciardiello M., Sagnotta A., Canonico G., De Marco G., Cappiello A., Pinotti E., Carlei F., Lisi G., Bagaglini G., Farrugia M., Meima-Van Praag E. M., Monteiro C., Pereira M., Botelho P., Quigley A., O'Neill A., Gaule L., Crone L., Arnold A., Grama F., Beuca A., Tulina I., Litvin A., Panyko A., Ossola M. E., Trujillo Diaz J., Marin Santos J. M., Alonso Batanero E., Gortazar de las Casas S., Soldevila Verdeguer C., Colas-Ruiz E., Talal El-Abur I., Garcia Dominguez M., Delorme M., Sauvain M., Ozmen B. B., Ozkan B. B., Calikoglu F., Kural S., Zafer F., Kaya Y., Yalcinkaya A., Kargici K., Tepe M. D., Tatar O. C., Kabadayi E., Yildirim A., Hurmuzlu D., Korkmaz K., Sharma P., Troller R., Hagan N., Mooney J., Light A., Tansey M., Bhojwani D., McGing R. M., Mallon A., Fadel M., Spilsbury C., James R., O'Brien S., Isaac A., Balasubramanya S., Sadik H., Gala T., Chen J. Y., Turner B., Goh E., Hassan K., Karam M., Mason P., Tzoumas N., Noton T., Seehra J. K., Ahmed N., Motiwale R., Tanna V., Argyriou A., Bylapudi S. K., Grace N., Latif S., Hounat A., Kiam J. S., Zaidi M., Elsamani K., Hughes C., Suresh A., Sinan L. O. H., El-Dalil D., Khoo E. J. M., Salim E. E., Stark D., Minhas N., Fowler G., Rees E., Giudiceandrea I., Bardon A., Jayawardena P., Dieseru N., Murphy A., Yates C., Ziolkowska K., Rafie A., Khoda F., Okocha M., Ashdown T., Vitish-Sharma P., Gilliland J., Toh S., Jones K., Devine A., Berry A., McDonnell S., Olivier J., Richardson G., Lim H. J., Slim N., Elsayeh K., Sammour T., Sarpanov A., Belev N., Dimitrov D., Dusek T., Ntomi V., Sotiropoulos G. C., Theodorou D., Nikiteas N., Balalis D., Antropoli C., Altomare D. F., Luglio G., De Palma G. D., Pedrazzani C., Simonelli L., Brozzetti S., Porcu A., Massani M., Grazi G. L., Izzo F., Delrio P., Restini E., Chetta G., Lantone G., Ferrari G., Lucchi A., De Prizio M., Caristo G., Borghi F., Petrucciani N., Huscher C., Cocorullo G., Tonini V., Medas F., Sica G., Cillara N., Anastasi A., Bianco F., Giuliani A., Carlini M., Selvaggi F., Sammarco G., Ozolins A., Malasonoks A., Andrejevic P., Tanis P., van de Ven A., Gerhards M., Ribeiro da Silva B., Silva A., Lima M. J., Kavanagh D., McCawley N., Bintintan V., Karamarkovic A., Sanz Ortega G., De Andres-Asenjo B., Nevado Garcia C., Garcia Florez L. J., Segura-Sampedro J. J., Blas Laina J. L., Ponchietti L., Buchwald P., Gialamas E., Ozben V., Rencuzogullari A., Gecim I. E., Altinel Y., Isik O., Yoldas T., Isik A., Leventoglu S., Erturk M. S., Guner A., Guler S. A., Attaallah W., Ugur M., Ozbalci G. S., Marzook H., Eardley N., Smolarek S., Morgan R., Roxburgh C., Lala A. K., Salama Y., Singh B., Khanna A., Evans M., Shaikh I., Maradi Thippeswamy K., Appleton B., Moug S., Smith I., Smart N., Shah P., Williams G., Khera G., Goede A., Varcada M., Parmar C., Duff S., Hargest R., Marriott P., Speake D., Ben Sassi A., Furfaro B., Daudu D., Golijanin N., Yek W. Y., Capasso G., Mansour L. T., Niu N., Seow W., Hamidovic A., Kulovic E., Letic E., Aljic A., Helez M., Banji-Kelan A., Dimitrova N., Kavradjieva P., Ivanov V., Jukaku A., Hadzhiev D., Gabarski A., Karamanliev M., Vladova P., Iliev S., Yotsov T., Vetsa K., Stavrinidou O., Papatheodorou P., Liassides T., Georgiou T., Al Nassrallah M., Altaf R., Negametzyanov M., Zagibova D., Foltys F., Stefanova H., Paspala A., Bompetsi G., Sidiropoulos T., Stamopoulos P., Triantafyllou A., Theodoropoulos C., Kimpizi A., Palyvou T., Charalabopoulos A., Syllaios A., Schizas D., Liatsou E., Baili E., Vagios I., Tomara N., Davakis S., Palumbo A., Foroni F., Dibra R., Papagni V., Urbani A., Rossin E., Nezi G., Romano P., Amendola A., Esposito E., Manigrasso M., Anoldo P., Vertaldi S., Gecchele G., Sabrina Z. S., Guerci C., Cammarata F., Lamperti G. M. B., Zaffaroni G., Benuzzi L., Ferrario L., Cigognini M., Mazzeo C., Badessi G., Pintabona G., Fassari A., Mingoli A., Cirillo B., D'Alterio C., Brachini G., Tancredi M., Zambon M., Aulicino M., Sapienza P., Liberatore P., Scanu A. M., Feo C. F., Iacomino A., Pelizzo P., Rossi S., Vigna S. A., Grossi U., Grillo V., Agnes A., Schena C. A., Marincola G., Oddi A., Perotti B., Mario V., Perri P., Zazza S., Aversano A., Scala D., Di Lauro K., Leongito M., Piccirillo M., Patrone R., Capuzzolo S., Vignotto C., Bao Q. R., Giuseppe C., Angarano E., Marino F., Pezzolla F., Gigante G., Magistro C., Crippa J., Maspero M., Carnevali P., Trapani R., Zonta S., Agostinelli L., Vittori L., Romeo L., Doria E., Farnesi F., Danna R., Andolfi E., Pellicano' G. A., Angelini M., Scricciolo M., Zanframundo C., Ciulli C., Ripamonti L., Cigagna L., Oldani M., Larcinese A., Rossi D., Picone E., Crescentini G., Marano A., Migliore M., Giuffrida M. C., Palagi S., Testa V., Borrello A., Lucarini A., Garofalo E., Canali G., Orlandi P., Nervegna F., Marchegiani F., Damoli I., Licata A., Trovato C., Alicata F., Sardo F., Milazzo M., Randisi B., Dominici D. M., Sartarelli L., Zanni M., Pisanu A., Soddu C., Delogu D., Erdas E., Campus F., Cappellacci F., Casti F., Marcialis J., Atzeni J., Podda M. G., Sensi B., Franceschilli M., Bellato V., Cannavera A., Putzu G., di Mola F. F., Picardi B., Solinas L., Loponte M., Rossi del Monte S., Di Martino C., Linari C., Spagni G., Capezzuoli L., Tirloni L., Nelli T., Caridi A., Elter C., Camassa M., D'Amico S., Bargellini T., Incollingo P., Montuori M., Maffione F., Romano L., Valiyeva S., Spoletini D., Menegon Tasselli F., Sciaudone G., Selvaggi L., Menna M. P., De Paola G., Fulginiti S., Truskovs A., Weiss C., Saknitis G., Rauscher J. T. R., Larnovskis J., Jeyarajan-Davidsson M., Nitisa D., Gille N., Reiser S. C., Roshan M. H. K., Leseman C., Chen J., van Dalen A. S., Top C., Detering R., Matos C., Silva C., Pinto D., Mendes J., Couto J., Leite M., Velez C., Damasio Cotovio M., Cinza A. M., Pedroso de Lima R., Boyle E., Yang H. W., Banerjee I., Rahmat S., Afzal Z., Reid C., Dumitrascu F., Croyle J. A., Gressmann K., Cullen N., Graham A., Nasehi A., Montano King C., Martin B., Stokell C., Sanderson N., Farnan R., Jassim S., Chan B., Chua Vi Long K., Kaka N., Pandey S., Neo W. X., Chitul A., Bezede C., Cincilei D., David A., Blaga M., Blaga S. N., Fagarasan V., Khetagurova M., Rodimov S., Kapustina A., Mekhralyzade A., Zabiyaka M., Jankovic U., Cuk V., Hajska M., Dubovsky M., Hrosova M., Ferancikova N., Camarero Rodriguez E., Laguna Alcantara F., Adarraga J., Jezieniecki C., Ruiz Soriano M., Gomez Sanz T., Suarez A., Sanchez Garcia C., Cifrian Canales I., Llosa Perez J., Merayo M., Urbieta A., Gegundez Simon A., Tone J. F., Gazo Martinez J., Vicario Bravo M., Chavarrias N., Gil Catalan A., Oseira A., Villalonga B., Jeri S., Perez Calvo J., Nogues A., Cros B., Yanez C., Utrilla Fornals A., Roldon Golet M., Colsa P., Gimenez Maurel T., Axmarker T., Chevallay M., Pham T. V., Sel E. K., Atar C., Aba M., Sarkin M., Akkaya Y. M., Durmaz A. G., Gullu H. F., Boga A., Aktas A., Bakar B., Demirel M. T., Hysejni X., Taser M., Guzel O. R., Bozbiyik O., Ozen D., Olmez M., Uyar B., Gulcek E., Kayacan G. S., Atici N., Gul O. F., Altiner S., Ibis B., Altunsu S., Banaz T., Diler C., Demirbas I., Usta M. A., Erkul O., Orman R., Salih S., Utkan N. Z., Acil C., Ozgur E., Maddahali M., Turhan A. B., Eskici A. B., Ular B., Dogru M., Ozturk O. U., Arslan E. R., Panahi Sharif A., Dikmen E., Ates J., Bircan R., Cavus T., Sever A. E., Balak B., Duman E., Altay L., Emanet O., Cullen F., Tan J. Y., Nathan A., Rottenberg A., Williams C. Y., Mitrofan C. G., Xu D., Bawa J. H., Morris P., Gordon D., Richmond G., Hui J. 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K., Osborne R., Baldemor S., Smyth S., Gilmour S., Ting A., Bozonelou I., Saunders P., Qhaireel Anwar Q.A., Tirimanna R., Jauhari S., Gardener A., Walker B., Wenban C., Reddy H., Conway-Jones R., Loganathan S., Clynch A., James C., Matey E., Cameron F., Roberts W., Gicquel A., Milliken C., Forbes J., Rubinchik P., Azmi A., Hawkes C., Cornett L., Adarkwah P., McConville R., O'Hara S., Tijare C., Parkes J., Yao L., Ahmad R., Shafiq U., Mhaisalkar A., Gurung A., de Stadler K., Elias S., Thomas T., Madras A., Jani A., Daler H.K., Tong K.S., Sundaralingam S.S., Szal A., Khan A., O'Sullivan C., Baker E., Joseph-Gubral J., Hadley E., Trivedi R., Igwelaezoh E., Barton H., Allison W., Hurst W., Alam F., Parkes I., Jamshaid M., Azizan N., Burgher T., Afzal A., Eltilib I., Zahid M., Sadiq O., Lloyd A., Ho R., Brazukas A., Li C.H., Kamdar M., Mohamed Nazeer M.N., Mighiu A., Kim D., Wilkins L., Kuo L., Rafe T., Maduka D., Cheema H., Farag K., Abdellatif M., Nzewi R., Kruczynska A., Grasselli H., Yousuff M., Bassi R., Mann A.K., Chopra J., Shaikh M., Sa D.S., Tsimplis V., Ghanchi A., Skene E., Asim K., Zaheer M., Chan S., Dalton H., Gibbons K., Adderley O., Chukwujindu I., Jayasuriya I., Sivanu K., Borumand M., Chick G., Bridges I., Tomlin J., McKenna J., Nandra N., Grieco C., Quek F.F., Mercer R., Brankin-Frisby T., Sattar A., Aslam A., Edelsten E., Shafi S., Kouli T., Ford V., Gurung F., Fernandes M., Deader N., Ponniah R., Jamieson S., Davies A., Taubwurcel J., Aung M.T., Desai R., Begum S., Jamadar T., Kangatharan A., Rzeszowski B., Ho C., Yap S.H.K., Prendergast M., Sethi R., Duku A., Lowe C., Bray J., Ghobrial M., Nichita V., Wagstaff A., Rengasamy E., Abu Hassan F., Mahmood H., Savill N., Shah S., Almeida T., Edwards A., Catchpole B., Halford Z., Carmichael A., Alsusa H., Boyd M., Williams J., Feyi-Waboso J., Patel M., Zeidan Z., Bailey E., Bapty J., Brazkiewicz M., Tremlett A., Pringle H., Mankal S., Chung W., Parry-Jones E., Anderson K., McForrester A., Stanley A., Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H.L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E.G., Lim K.H., Chohan N., Thaker A., Thompson B., Ahari D., Burdekin E., Okwu U., Akintunde A., Lhaf F., Douthwaite J., Govindan R., Leelamanthep S., Gull E., Wright F., Dundas L., Mackdermott N., Burchi-Khairy T., Campbell I., Walsh J., Yeo J.Y., Meehan S., Banerjee D., Fu M., Kawka M., Ali T., Hussain Z., Thomas C., Ahmad H., Moroney J., Yick C., Risquet R., Ntuiabane D., Shimato M., Khan M., Ilangovan S., Vaselli N.M., Smithers R., Uhanowita Marage R., Valnarov-Boulter A., Kayran J., Banerjee M., Parekh-Hill N., Hooper A., Bowen J., Jagdish R., McQuoid C., Khan N., O'Hare R., Jeffery S., Zahid A., Elsworth C., Walter L., Dhillon S., Rao S., Anthony A., Ashaye A., Phillips N., Faderani R., Pengelly S., Choi S., Kwak S.Y., Lau Y.H.L., Bagheri K., Ong D.Y.C., Kerr E., Falconer K., Clancy N., Douglas S., Zhang Y., Greenfield F., Mutanga I., McAlinden J., Willis L., Adefolaju A., Agarwal H., Barter R., Harris G., Spencer G., Lee M.W., Vadiveloo V.T., Herbert G., Patel R., Shah M., El Falaha S., Wong C., Soare C., Akram J., Bozhkova L., Ma Y., Vo U.G., Tan H.W.N., Leto L., Kamal M.A., Hadzhieva E., Krastev P., Tonchev P., Kokkinos G., Pozotou I., Sabbagh D., Votava J., St F., Koliakos N., Tsaparas P., Zografos G., Mantas D., Tsourouflis G., Fradelos E., Trigiante G., Labellarte G., Resta G., Capelli G., D'Amore A., Verlingieri V., Campagnaro T., Maffioli A., Viscosi F., De Lucia C., Meneghini S., Fancellu A., Colella M., Biondi A., De Peppo V., Pace U., Albino V., Gattulli D., Piangerelli A., Kalivaci D., Sisto G., Mazzola M., Caneparo A., Lunghi E.G., Nespoli L.C., Angrisani M., Langone A., Gelarda E., Virgilio E., Angelini E., Fornasier C., Asero S., Filippone E., Frongia F., Calo P.G., Panaccio P., Ipponi P., Gili S., Braccio B., Tiesi V., Stolcers K., Kokaine L., Novikovs V., Capel L., Bastiaenen V., Heijmans H., Henriques S., Gan S.Z., Ramanayake H., Nolan M., Temperley H., Ciofic E., Pop B.A., Kurtenkov M., Jovanovic M., Vician M., Egea Arias P., Beltran de Heredia J., Labalde Martinez M., De Santiago Alvarez I., Alvarez-Gallego M., Rodriguez Artigas J.M., Dwidar O., Korkmaz H.K., Eray I.C., Meric S., Aydin R., Cetin B., Karaca B.E., Kuyumcu O.F., Yuksel E., Uprak T.K., Karabulut K., Kavukcu E., Mansor A., Hackett R., Zammit-Maempel M., Sabaratnam R., Maan A., Ferarrio I., Dixon L., Halai H., Sethi S., Nelson L., Grassam-Rowe A., Krishnan E., Deeny D., McKeever M., George Pandeth A., Dhavala P., Sreenivasan S., Sundaram Venkatesan G., Zhu L., Atiyah Z., Gregory J., Morey T., Seymour Z., Holdsworth L., Abdelmahmoud S., Bourhill J., Bisheet G., Shaw J., Kulkarni K., Kumarakulasingam P., Pillay S., Al-Habsi R., Kungwengwe G., Richards J., Davoudi K., Ibrahim B., Tailor B., Zayed M., Chen F., Bailey S., Sheefat S., Nawaz G., Pawar R., Marsh S., Sam Z.H., Roy Bentley S., Simpson C., Hughes J., Lim Y., Ooi R., Toh W.H., Mannion P., Lovett A., Kincius A., Hussein S., Kirby E., Beckett R.G., Salmon J., Glynn T., Choo S.Y., Lyons S., Browne D., Ravindran W., Ahmad S., Zhu X., McNulty J., McCarthy L., Ng J., Karmally Z., McTeir K., Hanna M., Tan E., Namdeo S., Schembri R., Pusey E., Sgrò, A, Blanco-Colino, R, Ahmed, Wur, Brindl, N, Gujjuri, Rr, Lapolla, P, Mills, Ec, Pérez-Ajates, S, Soares, A, Varghese, C, Xu, W, Mclean, Ka, Chapman, Sj, Espín-Basany, E, Glasbey, Jc, Mihaljevic, A, Nepogodiev, D, Pata, F, Pellino, G, Pockney, P, Dudi-Venkata, Nn, Egoroff, N, Ludbrook, I, Raubenheimer, K, Richards, T, Delibegovic, S, Salibasic, M, Amjad, T, Dörr-Harim, C, Gedeon, N, Gsenger, J, Tachezy, M, Bini, S, Gallo, G, Gori, A, Picciariello, A, Podda, M, Riboni, C, Machatschek, Mj, Nguyen, A, Jakubauskas, M, Kryzauskas, M, Poskus, T, Kuiper, Sz, Wang, J, Wells, Ci, Bissett, Ip, Augestad, Km, Steinholt, I, Vieira, Bn, Juloski, J, Anabitarte Bautista, O, El Kasmy El Kasmy, Y, Martín-Borregón, P, Ossola Revilla, M, Van Straten, S, Aktas, Mk, Baki, Be, Akhbari, M, Baker, D, Bhatia, S, Brown, S, Cambridge, W, Kamarajah, Sk, Khaw, Ra, Kouli, O, Murray, V, Trout, I, Yasin, I, Wong, J Y, Reyhani, H, Wong, Khf, Pancharatnam, R, Chia, Wl, Walmsley, A, Hassane, A, Saeed, D, Wang, B, Walters, B, Nowinka, Z, Alsaif, A, Mirza, M, Foster, K, Luu, J, Kakodkar, P, Hughes, Jt, Yogarajah, T, Antypas, A, Rahman, A, Bradbury, M, Mclarnon, M, Nagi, S, Riad, Am, Erotocritou, M, Kyriacou, H, Kaminskaite, V, Alfadhel, S, Fatimah Hussain, Q, Handa, A, Massy-Westropp, C, Čustović, S, Dimov, R, Mughal, H, Slavchev, M, Ivanov, T, Gouvas, N, Hegazi, A, Kocián, P, Kjaer, Md, Mark-Christensen, A, Papakonstantinou, D, Machairas, N, Triantafyllou, T, Garoufalia, Z, Korkolis, D, Castaldi, A, Giaccari, S, Spolverato, G, Pagano, G, Milone, M, Turri, G, Colombo, F, Cucinotta, E, Poillucci, G, Perra, T, Tutino, R, Belia, F, Coletta, D, Belli, A, Rega, D, Cianci, P, Pirozzolo, G, Di Lena, M, Perrone, F, Giani, A, Lovisetto, F, Grassia, M, Pipitone Federico, N, Ferrara, F, Biancafarina, A, Tamini, N, Sinibaldi, G, Tuminello, F, Galleano, R, Sasia, D, Bragaglia, L, de Manzoni Garberini, A, Pesce, A, Cassaro, F, Venturelli, P, Canu, Gl, Esposito, G, Campanelli, M, Cardia, R, Ricciardiello, M, Sagnotta, A, Canonico, G, De Marco, G, Cappiello, A, Pinotti, E, Carlei, F, Lisi, G, Bagaglini, G, Farrugia, M, Meima - van Praag, Em, Monteiro, C, Pereira, M, Botelho, P, Quigley, A, O'Neill, A, Gaule, L, Crone, L, Arnold, A, Grama, F, Beuca, A, Tulina, I, Litvin, A, Panyko, A, Ossola, Me, Trujillo Díaz, J, Marín Santos, Jm, Alonso Batanero, E, Gortázar de las Casas, S, Soldevila Verdeguer, C, Colás-Ruiz, E, Talal El-Abur, I, García Domínguez, M, Delorme, M, Sauvain, M, Ozmen, Bb, Ozkan, Bb, Calikoglu, F, Kural, S, Zafer, F, Kaya, Y, Yalcinkaya, A, Kargici, K, Tepe, Md, Tatar, Oc, Kabadayi, E, Yıldırım, A, Hurmuzlu, D, Korkmaz, K, Sharma, P, Troller, R, Hagan, N, Mooney, J, Light, A, Tansey, M, Bhojwani, D, Mcging, Rm, Mallon, A, Fadel, M, Spilsbury, C, James, R, O’Brien, S, Isaac, A, Balasubramanya, S, Sadik, H, Gala, T, Chen, Jy, Turner, B, Goh, E, Hassan, K, Karam, M, Mason, P, Tzoumas, N, Noton, T, Seehra, Jk, Ahmed, N, Motiwale, R, Tanna, V, Argyriou, A, Bylapudi, Sk, Grace, N, Latif, S, Hounat, A, Kiam, J, Zaidi, M, Elsamani, K, Hughes, C, Suresh, A, Sinan, Loh, El-Dalil, D, Khoo, Ejm, Salim, Ee, Stark, D, Minhas, N, Fowler, G, Rees, E, Giudiceandrea, I, Bardon, A, Jayawardena, P, Dieseru, N, Murphy, A, Yates, C, Ziolkowska, K, Rafie, A, Khoda, F, Okocha, M, Ashdown, T, Vitish-Sharma, P, Gilliland, J, Toh, S, Jones, K, Devine, A, Berry, A, Mcdonnell, S, Olivier, J, Richardson, G, Lim, Hj, Slim, N, Elsayeh, K, Sammour, T, Sarpanov, A, Belev, N, Dimitrov, D, Dušek, T, Ntomi, V, Sotiropoulos, Gc, Theodorou, D, Nikiteas, N, Balalis, D, Antropoli, C, Altomare, Df, Luglio, G, De Palma, Gd, Pedrazzani, C, Simonelli, L, Brozzetti, S, Porcu, A, Massani, M, Grazi, Gl, Izzo, F, Delrio, P, Restini, E, Chetta, G, Lantone, G, Ferrari, G, Lucchi, A, De Prizio, M, Caristo, G, Borghi, F, Petrucciani, N, Huscher, C, Cocorullo, G, Tonini, V, Medas, F, Sica, G, Cillara, N, Anastasi, A, Bianco, F, Giuliani, A, Carlini, M, Selvaggi, F, Sammarco, G, Ozoliņš, A, Malašonoks, A, Andrejevic, P, Tanis, P, van de Ven, A, Gerhards, M, Ribeiro da Silva, B, Silva, A, Lima, Mj, Kavanagh, D, Mccawley, N, Bintintan, V, Karamarkovic, A, Sanz Ortega, G, De Andrés-Asenjo, B, Nevado García, C, García Flórez, Lj, Segura-Sampedro, Jj, Blas Laina, Jl, Ponchietti, L, Buchwald, P, Gialamas, E, Ozben, V, Rencuzogullari, A, Gecim, İe, Altinel, Y, Isik, O, Yoldas, T, Isik, A, Leventoğlu, S, Ertürk, M, Guner, A, Güler, Sa, Attaallah, W, Ugur, M, Özbalcı, G, Marzook, H, Eardley, N, Smolarek, S, Morgan, R, Roxburgh, C, Lala, Ak, Salama, Y, Singh, B, Khanna, A, Evans, M, Shaikh, I, Maradi Thippeswamy, K, Appleton, B, Moug, S, Smith, I, Smart, N, Shah, P, Williams, G, Khera, G, Goede, A, Varcada, M, Parmar, C, Duff, S, Hargest, R, Marriott, P, Speake, D, Ben Sassi, A, Furfaro, B, Daudu, D, Golijanin, N, Yek, Wy, Capasso, G, Mansour, Lt, Niu, N, Seow, W, Hamidovic, A, Kulovic, E, Letic, E, Aljić, A, Helez, M, Banji-Kelan, A, Dimitrova, N, Kavradjieva, P, Ivanov, V, Jukaku, A, Hadzhiev, D, Gabarski, A, Karamanliev, M, Vladova, P, Iliev, S, Yotsov, T, Ευσταθίου, Η, Vetsa, K, Stavrinidou, O, Papatheodorou, P, Liassides, T, Georgiou, T, Al Nassrallah, M, Altaf, R, Negametzyanov, M, Zagibová, D, Foltys, F, Štefanová, H, Paspala, A, Bompetsi, G, Sidiropoulos, T, Stamopoulos, P, Triantafyllou, A, Theodoropoulos, C, Kimpizi, A, Palyvou, T, Charalabopoulos, A, Syllaios, A, Schizas, D, Liatsou, E, Baili, E, Vagios, I, Tomara, N, Davakis, S, Palumbo, A, Foroni, F, Dibra, R, Papagni, V, Urbani, A, Rossin, E, Nezi, G, Romano, P, Amendola, A, Esposito, E, Manigrasso, M, Anoldo, P, Vertaldi, S, Gecchele, G, Sabrina, Z, Guerci, C, Cammarata, F, Lamperti, Gmb, Zaffaroni, G, Benuzzi, L, Ferrario, L, Cigognini, M, Mazzeo, C, Badessi, G, Pintabona, G, Fassari, A, Mingoli, A, Cirillo, B, D’Alterio, C, Brachini, G, Tancredi, M, Zambon, M, Aulicino, M, Sapienza, P, Liberatore, P, Scanu, Am, Feo, Cf, Iacomino, A, Pelizzo, P, Rossi, S, Vigna, Sa, Grossi, U, Grillo, V, Agnes, A, Schena, Ca, Marincola, G, Oddi, A, Perotti, B, Mario, V, Perri, P, Zazza, S, Aversano, A, Scala, D, Di Lauro, K, Leongito, M, Piccirillo, M, Patrone, R, Capuzzolo, S, Vignotto, C, Bao, Qr, Giuseppe, C, Angarano, E, Marino, F, Pezzolla, F, Gigante, G, Magistro, C, Crippa, J, Maspero, M, Carnevali, P, Trapani, R, Zonta, S, Agostinelli, L, Vittori, L, Romeo, L, Doria, E, Farnesi, F, Danna, R, Andolfi, E, Pellicano’, Ga, Angelini, M, Scricciolo, M, Zanframundo, C, Ciulli, C, Ripamonti, L, Cigagna, L, Oldani, M, Larcinese, A, Rossi, D, Picone, E, Crescentini, G, Marano, A, Migliore, M, Giuffrida, Mc, Palagi, S, Testa, V, Borrello, A, Lucarini, A, Garofalo, E, Canali, G, Orlandi, P, Nervegna, F, Marchegiani, F, Damoli, I, Licata, A, Trovato, C, Alicata, F, Sardo, F, Milazzo, M, Randisi, B, Dominici, Dm, Sartarelli, L, Zanni, M, Pisanu, A, Soddu, C, Delogu, D, Erdas, E, Campus, F, Cappellacci, F, Casti, F, Marcialis, J, Atzeni, J, Podda, Mg, Sensi, B, Franceschilli, M, Bellato, V, Cannavera, A, Putzu, G, di Mola, Ff, Picardi, B, Solinas, L, Loponte, M, Rossi del Monte, S, Di Martino, C, Linari, C, Spagni, G, Capezzuoli, L, Tirloni, L, Nelli, T, Caridi, A, Elter, C, Camassa, M, D'Amico, S, Bargellini, T, Incollingo, P, Montuori, M, Maffione, F, Romano, L, Valiyeva, S, Spoletini, D, Menegon Tasselli, F, Sciaudone, G, Selvaggi, L, Menna, Mp, De Paola, G, Fulginiti, S, Truskovs, A, Weiß, C, Saknītis, G, Rauscher, Jtr, Larnovskis, J, Jeyarajan-Davidsson, M, Nitisa, D, Gille, N, Reiser, Sc, Roshan, Mhk, Leseman, C, Chen, J, van Dalen, A, Top, C, Detering, R, Matos, C, Silva, C, Pinto, D, Mendes, J, Couto, J, Leite, M, Velez, C, Damasio Cotovio, M, Cinza, Am, Pedroso de Lima, R, Boyle, E, Yang, Hw, Banerjee, I, Rahmat, S, Afzal, Z, Reid, C, Dumitrascu, F, Croyle, Ja, Gressmann, K, Cullen, N, Graham, A, Nasehi, A, Montano King, C, Martin, B, Stokell, C, Sanderson, N, Farnan, R, Jassim, S, Chan, B, Chua Vi Long, K, Kaka, N, Pandey, S, Neo, Wx, Chitul, A, Bezede, C, Cincilei, D, David, A, Blaga, M, Blaga, Sn, Fagarasan, V, Khetagurova, M, Rodimov, S, Kapustina, A, Mekhralyzade, A, Zabiyaka, M, Janković, U, Cuk, V, Hájska, M, Dubovský, M, Hrošová, M, Ferancikova, N, Camarero Rodríguez, E, Laguna Alcántara, F, Adarraga, J, Jezieniecki, C, Ruiz Soriano, M, Gómez Sanz, T, Suarez, A, Sánchez García, C, Cifrian Canales, I, Llosa Pérez, J, Merayo, M, Urbieta, A, Gegúndez Simón, A, Tone, Jf, Gazo Martínez, J, Vicario Bravo, M, Chavarrias, N, Gil Catalán, A, Oseira, A, Villalonga, B, Jeri, S, Perez Calvo, J, Nogués, A, Cros, B, Yánez, C, Utrilla Fornals, A, Roldón Golet, M, Colsa, P, Gimenez Maurel, T, Axmarker, T, Chevallay, M, Pham, Tv, Sel, Ek, Atar, C, Aba, M, Sarkin, M, Akkaya, Ym, Durmaz, Ag, Gullu, Hf, Boğa, A, Aktaş, A, Bakar, B, Demirel, Mt, Hysejni, X, Taser, M, Guzel, Or, Bozbiyik, O, Özen, D, Ölmez, M, Uyar, B, Gülçek, E, Kayacan, G, Atıcı, N, Gul, Of, Altiner, S, Ibis, B, Altunsu, S, Banaz, T, Diler, C, Demirbas, I, Usta, Ma, Erkul, O, Orman, R, Salih, S, Utkan, Nz, Acil, C, Ozgur, E, Maddahali, M, Turhan, Ab, Eskici, Ab, Ular, B, Doğru, M, Öztürk, Ou, Arslan, Er, Panahi Sharif, A, Dikmen, E, Ates, J, Bircan, R, Cavus, T, Sever, Ae, Balak, B, Duman, E, Altay, L, Emanet, O, Cullen, F, Tan, Jy, Nathan, A, Rottenberg, A, Williams, Cy, Mitrofan, Cg, Xu, D, Bawa, Jh, Morris, P, Gordon, D, Richmond, G, Hui, Jc, Ighomereho, O, Rocks, R, Mccabe, S, Fitzpatrick, A, Nicoletti, J, Auterson, L, Darrah, N, Soh, Vwy, Ong, C, Utukuri, M, Gallagher, C, Stuart, Lm, Hipolito, M, Douglas, N, Ghazal, R, Parris, G, Catchpole, J, Bryden, M, Jamal, S, Karim, Z, Lyon-Dean, C, Rowley, G, Lee, K, Whitehurst, O, Mirza, A, Sheikh, F, Yousaf, H, Bilbao, J, Sinclair, R, Takar, S, Kressel, H, Chan, V, Schack, K, Osborne, R, Baldemor, S, Smyth, S, Gilmour, S, Ting, A, Bozonelou, I, Saunders, P, Qhaireel Anwar, Qa, Tirimanna, R, Jauhari, S, Gardener, A, Walker, B, Wenban, C, Reddy, H, Conway-Jones, R, Loganathan, S, Clynch, A, James, C, Matey, E, Cameron, F, Roberts, W, Gicquel, A, Milliken, C, Forbes, J, Rubinchik, P, Azmi, A, Hawkes, C, Cornett, L, Adarkwah, P, Mcconville, R, O'Hara, S, Tijare, C, Parkes, J, Yao, L, Ahmad, R, Shafiq, U, Mhaisalkar, A, Gurung, A, de Stadler, K, Elias, S, Thomas, T, Madras, A, Jani, A, Daler, Hk, Tong, K, Sundaralingam, S, Szal, A, Khan, A, O'Sullivan, C, Baker, E, Joseph-Gubral, J, Hadley, E, Trivedi, R, Igwelaezoh, E, Barton, H, Allison, W, Hurst, W, Alam, F, Parkes, I, Jamshaid, M, Azizan, N, Burgher, T, Afzal, A, Eltilib, I, Zahid, M, Sadiq, O, Lloyd, A, Ho, R, Brazukas, A, Li, Ch, Kamdar, M, Mohamed Nazeer, Mn, Mighiu, A, Kim, D, Wilkins, L, Kuo, L, Rafe, T, Maduka, D, Cheema, H, Farag, K, Abdellatif, M, Nzewi, R, Kruczynska, A, Grasselli, H, Yousuff, M, Bassi, R, Mann, Ak, Chopra, J, Shaikh, M, D Sa, S, Tsimplis, V, Ghanchi, A, Skene, E, Asim, K, Zaheer, M, Chan, S, Dalton, H, Gibbons, K, Adderley, O, Chukwujindu, I, Jayasuriya, I, Sivanu, K, Borumand, M, Chick, G, Bridges, I, Tomlin, J, Mckenna, J, Nandra, N, Grieco, C, Quek, Ff, Mercer, R, Brankin-Frisby, T, Sattar, A, Aslam, A, Edelsten, E, Shafi, S, Kouli, T, Ford, V, Gurung, F, Fernandes, M, Deader, N, Ponniah, R, Jamieson, S, Davies, A, Taubwurcel, J, Aung, Mt, Desai, R, Begum, S, Jamadar, T, Kangatharan, A, Rzeszowski, B, Ho, C, Yap, Shk, Prendergast, M, Sethi, R, Duku, A, Lowe, C, Bray, J, Ghobrial, M, Nichita, V, Wagstaff, A, Rengasamy, E, Abu Hassan, F, Mahmood, H, Savill, N, Shah, S, Almeida, T, Edwards, A, Catchpole, B, Halford, Z, Carmichael, A, Alsusa, H, Boyd, M, Williams, J, Feyi-Waboso, J, Patel, M, Zeidan, Z, Bailey, E, Bapty, J, Brazkiewicz, M, Tremlett, A, Pringle, H, Mankal, S, Chung, W, Parry-Jones, E, Anderson, K, Mcforrester, A, Stanley, A, Hoather, A, Wise, H, Laid, I, Scriven, J, Braniste, A, Wilson, A, Le Blevec, L, Pakunwanich, N, Evans, N, Chong, Hl, White, C, Hunter, J, Haque, M, Vanalia, P, Murdoch, S, Choudhary, T, Mccann, A, Harun, A, Shah, H, Hunt, S, Shafiq, Y, Bickley-Morris, E, Emms, L, Dare, M, Akula, Y, Deliyannis, E, Mayes, F, Ellacott, M, Zagorac, Z, Farren, A, Manning, C, Hughed, C, Stewart, Eg, Lim, Kh, Chohan, N, Thaker, A, Thompson, B, Ahari, D, Burdekin, E, Okwu, U, Akintunde, A, Lhaf, F, Douthwaite, J, Govindan, R, Leelamanthep, S, Gull, E, Wright, F, Dundas, L, Mackdermott, N, Burchi-Khairy, T, Campbell, I, Walsh, J, Yeo, Jy, Meehan, S, Banerjee, D, Fu, M, Kawka, M, Ali, T, Hussain, Z, Thomas, C, Ahmad, H, Moroney, J, Yick, C, Risquet, R, Ntuiabane, D, Shimato, M, Khan, M, Ilangovan, S, Vaselli, Nm, Smithers, R, Uhanowita Marage, R, Valnarov-Boulter, A, Kayran, J, Banerjee, M, Parekh-Hill, N, Hooper, A, Bowen, J, Jagdish, R, Mcquoid, C, Khan, N, O Hare, R, Jeffery, S, Zahid, A, Elsworth, C, Walter, L, Dhillon, S, Rao, S, Anthony, A, Ashaye, A, Phillips, N, Faderani, R, Pengelly, S, Choi, S, Kwak, Sy, Lau, Yhl, Bagheri, K, Ong, Dyc, Kerr, E, Falconer, K, Clancy, N, Douglas, S, Zhang, Y, Greenfield, F, Mutanga, I, Mcalinden, J, Willis, L, Adefolaju, A, Agarwal, H, Barter, R, Harris, G, Spencer, G, Lee, Mw, V Vadiveloo, T, Herbert, G, Patel, R, Shah, M, El Falaha, S, Wong, C, Soare, C, Akram, J, Bozhkova, L, Ma, Y, Vo, Ug, Tan, Hwn, Leto, L, Kamal, Ma, Hadzhieva, E, Krastev, P, Tonchev, P, Kokkinos, G, Pozotou, I, Sabbagh, D, Votava, J, St, F, Koliakos, N, Tsaparas, P, Zografos, G, Mantas, D, Tsourouflis, G, Fradelos, E, Trigiante, G, Labellarte, G, Resta, G, Capelli, G, D'Amore, A, Verlingieri, V, Campagnaro, T, Maffioli, A, Viscosi, F, De Lucia, C, Meneghini, S, Fancellu, A, Colella, M, Biondi, A, De Peppo, V, Pace, U, Albino, V, Gattulli, D, Piangerelli, A, Kalivaci, D, Sisto, G, Mazzola, M, Caneparo, A, Lunghi, Eg, Nespoli, Lc, Angrisani, M, Langone, A, Gelarda, E, Virgilio, E, Angelini, E, Fornasier, C, Asero, S, Filippone, E, Frongia, F, Calò, Pg, Panaccio, P, Ipponi, P, Gili, S, Braccio, B, Tiesi, V, Stolcers, K, Kokaine, L, Novikovs, V, Capel, L, Bastiaenen, V, Heijmans, H, Henriques, S, Gan, Sz, Ramanayake, H, Nolan, M, Temperley, H, Ciofic, E, Pop, Ba, Kurtenkov, M, Jovanović, M, Vician, M, Egea Arias, P, Beltrán de Heredia, J, Labalde Martinez, M, De Santiago Alvarez, I, Alvarez-Gallego, M, Rodriguez Artigas, Jm, Dwidar, O, Korkmaz, Hk, Eray, Ic, Meriç, S, Aydin, R, Çetin, B, Karaca, Be, Kuyumcu, Of, Yüksel, E, Uprak, Tk, Karabulut, K, Kavukçu, E, Mansor, A, Hackett, R, Zammit-Maempel, M, Sabaratnam, R, Maan, A, Ferarrio, I, Dixon, L, Halai, H, Sethi, S, Nelson, L, Grassam-rowe, A, Krishnan, E, Deeny, D, Mckeever, M, George Pandeth, A, Dhavala, P, Sreenivasan, S, Sundaram Venkatesan, G, Zhu, L, Atiyah, Z, Gregory, J, Morey, T, Seymour, Z, Holdsworth, L, Abdelmahmoud, S, Bourhill, J, Bisheet, G, Shaw, J, Kulkarni, K, Kumarakulasingam, P, Pillay, S, Al-Habsi, R, Kungwengwe, G, Richards, J, Davoudi, K, Ibrahim, B, Tailor, B, Zayed, M, Chen, F, Bailey, S, Sheefat, S, Nawaz, G, Pawar, R, Marsh, S, Sam, Zh, Roy Bentley, S, Simpson, C, Hughes, J, Lim, Y, Ooi, R, Toh, Wh, Mannion, P, Lovett, A, Kinčius, A, Hussein, S, Kirby, E, Beckett, Rg, Salmon, J, Glynn, T, Choo, Sy, Lyons, S, Browne, D, Ravindran, W, Ahmad, S, Zhu, X, Mcnulty, J, Mccarthy, L, Ng, J, Karmally, Z, Mcteir, K, Hanna, M, Tan, E, Namdeo, S, Schembri, R, Pusey, E, Sgro, A, Ahmed, W, Gujjuri, R, Mills, E, Perez-Ajates, S, Mclean, K, Chapman, S, Espin-Basany, E, Glasbey, J, Dudi-Venkata, N, Dorr-Harim, C, Machatschek, M, Kuiper, S, Wells, C, Bissett, I, Augestad, K, Vieira, B, Martin-Borregon, P, Aktas, M, Baki, B, Kamarajah, S, Khaw, R, Wong, J, Wong, K, Chia, W, Riad, A, Custovic, S, Kocian, P, Kjaer, M, Canu, G, Meima-Van Praag, E, Ossola, M, Trujillo Diaz, J, Marin Santos, J, Gortazar de las Casas, S, Colas-Ruiz, E, Garcia Dominguez, M, Ozmen, B, Ozkan, B, Tepe, M, Tatar, O, Yildirim, A, Mcging, R, O'Brien, S, Seehra, J, Bylapudi, S, Sinan, L, Khoo, E, Salim, E, Lim, H, Dusek, T, Sotiropoulos, G, Altomare, D, De Palma, G, Grazi, G, Ozolins, A, Malasonoks, A, Lima, M, De Andres-Asenjo, B, Nevado Garcia, C, Garcia Florez, L, Segura-Sampedro, J, Blas Laina, J, Gecim, I, Leventoglu, S, Erturk, M, Guler, S, Ozbalci, G, Lala, A, Yek, W, Mansour, L, Aljic, A, Zagibova, D, Stefanova, H, Lamperti, G, D'Alterio, C, Scanu, A, Feo, C, Vigna, S, Schena, C, Bao, Q, Pellicano', G, Giuffrida, M, Dominici, D, di Mola, F, Menna, M, Weiss, C, Saknitis, G, Rauscher, J, Reiser, S, Roshan, M, Cinza, A, Yang, H, Croyle, J, Neo, W, Blaga, S, Jankovic, U, Hajska, M, Dubovsky, M, Hrosova, M, Camarero Rodriguez, E, Laguna Alcantara, F, Gomez Sanz, T, Sanchez Garcia, C, Llosa Perez, J, Gegundez Simon, A, Tone, J, Gazo Martinez, J, Gil Catalan, A, Nogues, A, Yanez, C, Roldon Golet, M, Pham, T, Sel, E, Akkaya, Y, Durmaz, A, Gullu, H, Boga, A, Aktas, A, Demirel, M, Guzel, O, Ozen, D, Olmez, M, Gulcek, E, Atici, N, Gul, O, Usta, M, Utkan, N, Turhan, A, Eskici, A, Dogru, M, Ozturk, O, Arslan, E, Sever, A, Tan, J, Williams, C, Mitrofan, C, Bawa, J, Hui, J, Soh, V, Stuart, L, Qhaireel Anwar, Q, Daler, H, Li, C, Mohamed Nazeer, M, Mann, A, Sa, D, Quek, F, Aung, M, Yap, S, Chong, H, Stewart, E, Lim, K, Yeo, J, Vaselli, N, O'Hare, R, Kwak, S, Lau, Y, Ong, D, Lee, M, Vadiveloo, V, Vo, U, Tan, H, Kamal, M, Lunghi, E, Nespoli, L, Calo, P, Gan, S, Pop, B, Jovanovic, M, Beltran de Heredia, J, Rodriguez Artigas, J, Korkmaz, H, Eray, I, Meric, S, Cetin, B, Karaca, B, Kuyumcu, O, Yuksel, E, Uprak, T, Kavukcu, E, Grassam-Rowe, A, Sam, Z, Toh, W, Kincius, A, Beckett, R, Choo, S, Sgro, A., Blanco-Colino, R., Ahmed, W. U. R., Brindl, N., Gujjuri, R. R., Lapolla, P., Mills, E. C., Perez-Ajates, S., Soares, A. S., Varghese, C., Xu, W., Mclean, K. A., Chapman, S. J., Espin-Basany, E., Glasbey, J. C., Mihaljevic, A., Nepogodiev, D., Pata, F., Pellino, G., Pockney, P., Dudi-Venkata, N. N., Egoroff, N., Ludbrook, I., Raubenheimer, K., Richards, T., Delibegovic, S., Salibasic, M., Amjad, T., Dorr-Harim, C., Gedeon, N., Gsenger, J., Tachezy, M., Bini, S., Gallo, G., Gori, A., Picciariello, A., Podda, M., Riboni, C., Machatschek, M. J., Nguyen, A., Jakubauskas, M., Kryzauskas, M., Poskus, T., Kuiper, S. Z., Wang, J., Wells, C. I., Bissett, I. P., Augestad, K. M., Steinholt, I., Vieira, B. N., Juloski, J., Anabitarte Bautista, O., El Kasmy El Kasmy, Y., Martin-Borregon, P., Ossola Revilla, M., Van Straten, S., Aktas, M. K., Baki, B. E., Akhbari, M., Baker, D., Bhatia, S., Brown, S., Cambridge, W., Kamarajah, S. K., Khaw, R. A., Kouli, O., Murray, V., Trout, I., Yasin, I., Wong, J. Y., Reyhani, H., Wong, K. H. F., Pancharatnam, R., Chia, W. L., Walmsley, A., Hassane, A., Saeed, D., Wang, B., Walters, B., Nowinka, Z., Alsaif, A., Mirza, M., Foster, K., Luu, J., Kakodkar, P., Hughes, J. T., Yogarajah, T., Antypas, A., Rahman, A., Bradbury, M., Mclarnon, M., Nagi, S., Riad, A. M., Erotocritou, M., Kyriacou, H., Kaminskaite, V., Alfadhel, S., Fatimah Hussain, Q., Handa, A., Massy-Westropp, C., Custovic, S., Dimov, R., Mughal, H., Slavchev, M., Ivanov, T., Gouvas, N., Hegazi, A., Kocian, P., Kjaer, M. D., Mark-Christensen, A., Papakonstantinou, D., Machairas, N., Triantafyllou, T., Garoufalia, Z., Korkolis, D., Castaldi, A., Giaccari, S., Spolverato, G., Pagano, G., Milone, M., Turri, G., Colombo, F., Cucinotta, E., Poillucci, G., Perra, T., Tutino, R., Belia, F., Coletta, D., Belli, A., Rega, D., Cianci, P., Pirozzolo, G., Di Lena, M., Perrone, F., Giani, A., Lovisetto, F., Grassia, M., Pipitone Federico, N. S., Ferrara, F., Biancafarina, A., Tamini, N., Sinibaldi, G., Tuminello, F., Galleano, R., Sasia, D., Bragaglia, L., de Manzoni Garberini, A., Pesce, A., Cassaro, F., Venturelli, P., Canu, G. L., Esposito, G., Campanelli, M., Cardia, R., Ricciardiello, M., Sagnotta, A., Canonico, G., De Marco, G., Cappiello, A., Pinotti, E., Carlei, F., Lisi, G., Bagaglini, G., Farrugia, M., Meima-Van Praag, E. M., Monteiro, C., Pereira, M., Botelho, P., Quigley, A., O'Neill, A., Gaule, L., Crone, L., Arnold, A., Grama, F., Beuca, A., Tulina, I., Litvin, A., Panyko, A., Ossola, M. E., Trujillo Diaz, J., Marin Santos, J. M., Alonso Batanero, E., Gortazar de las Casas, S., Soldevila Verdeguer, C., Colas-Ruiz, E., Talal El-Abur, I., Garcia Dominguez, M., Delorme, M., Sauvain, M., Ozmen, B. B., Ozkan, B. B., Calikoglu, F., Kural, S., Zafer, F., Kaya, Y., Yalcinkaya, A., Kargici, K., Tepe, M. D., Tatar, O. C., Kabadayi, E., Yildirim, A., Hurmuzlu, D., Korkmaz, K., Sharma, P., Troller, R., Hagan, N., Mooney, J., Light, A., Tansey, M., Bhojwani, D., Mcging, R. M., Mallon, A., Fadel, M., Spilsbury, C., James, R., O'Brien, S., Isaac, A., Balasubramanya, S., Sadik, H., Gala, T., Chen, J. Y., Turner, B., Goh, E., Hassan, K., Karam, M., Mason, P., Tzoumas, N., Noton, T., Seehra, J. K., Ahmed, N., Motiwale, R., Tanna, V., Argyriou, A., Bylapudi, S. K., Grace, N., Latif, S., Hounat, A., Kiam, J. S., Zaidi, M., Elsamani, K., Hughes, C., Suresh, A., Sinan, L. O. H., El-Dalil, D., Khoo, E. J. M., Salim, E. E., Stark, D., Minhas, N., Fowler, G., Rees, E., Giudiceandrea, I., Bardon, A., Jayawardena, P., Dieseru, N., Murphy, A., Yates, C., Ziolkowska, K., Rafie, A., Khoda, F., Okocha, M., Ashdown, T., Vitish-Sharma, P., Gilliland, J., Toh, S., Jones, K., Devine, A., Berry, A., Mcdonnell, S., Olivier, J., Richardson, G., Lim, H. J., Slim, N., Elsayeh, K., Sammour, T., Sarpanov, A., Belev, N., Dimitrov, D., Dusek, T., Ntomi, V., Sotiropoulos, G. C., Theodorou, D., Nikiteas, N., Balalis, D., Antropoli, C., Altomare, D. F., Luglio, G., De Palma, G. D., Pedrazzani, C., Simonelli, L., Brozzetti, S., Porcu, A., Massani, M., Grazi, G. L., Izzo, F., Delrio, P., Restini, E., Chetta, G., Lantone, G., Ferrari, G., Lucchi, A., De Prizio, M., Caristo, G., Borghi, F., Petrucciani, N., Huscher, C., Cocorullo, G., Tonini, V., Medas, F., Sica, G., Cillara, N., Anastasi, A., Bianco, F., Giuliani, A., Carlini, M., Selvaggi, F., Sammarco, G., Ozolins, A., Malasonoks, A., Andrejevic, P., Tanis, P., van de Ven, A., Gerhards, M., Ribeiro da Silva, B., Silva, A., Lima, M. J., Kavanagh, D., Mccawley, N., Bintintan, V., Karamarkovic, A., Sanz Ortega, G., De Andres-Asenjo, B., Nevado Garcia, C., Garcia Florez, L. J., Segura-Sampedro, J. J., Blas Laina, J. L., Ponchietti, L., Buchwald, P., Gialamas, E., Ozben, V., Rencuzogullari, A., Gecim, I. E., Altinel, Y., Isik, O., Yoldas, T., Isik, A., Leventoglu, S., Erturk, M. S., Guner, A., Guler, S. A., Attaallah, W., Ugur, M., Ozbalci, G. S., Marzook, H., Eardley, N., Smolarek, S., Morgan, R., Roxburgh, C., Lala, A. K., Salama, Y., Singh, B., Khanna, A., Evans, M., Shaikh, I., Maradi Thippeswamy, K., Appleton, B., Moug, S., Smith, I., Smart, N., Shah, P., Williams, G., Khera, G., Goede, A., Varcada, M., Parmar, C., Duff, S., Hargest, R., Marriott, P., Speake, D., Ben Sassi, A., Furfaro, B., Daudu, D., Golijanin, N., Yek, W. Y., Capasso, G., Mansour, L. T., Niu, N., Seow, W., Hamidovic, A., Kulovic, E., Letic, E., Aljic, A., Helez, M., Banji-Kelan, A., Dimitrova, N., Kavradjieva, P., Ivanov, V., Jukaku, A., Hadzhiev, D., Gabarski, A., Karamanliev, M., Vladova, P., Iliev, S., Yotsov, T., Vetsa, K., Stavrinidou, O., Papatheodorou, P., Liassides, T., Georgiou, T., Al Nassrallah, M., Altaf, R., Negametzyanov, M., Zagibova, D., Foltys, F., Stefanova, H., Paspala, A., Bompetsi, G., Sidiropoulos, T., Stamopoulos, P., Triantafyllou, A., Theodoropoulos, C., Kimpizi, A., Palyvou, T., Charalabopoulos, A., Syllaios, A., Schizas, D., Liatsou, E., Baili, E., Vagios, I., Tomara, N., Davakis, S., Palumbo, A., Foroni, F., Dibra, R., Papagni, V., Urbani, A., Rossin, E., Nezi, G., Romano, P., Amendola, A., Esposito, E., Manigrasso, M., Anoldo, P., Vertaldi, S., Gecchele, G., Sabrina, Z. S., Guerci, C., Cammarata, F., Lamperti, G. M. B., Zaffaroni, G., Benuzzi, L., Ferrario, L., Cigognini, M., Mazzeo, C., Badessi, G., Pintabona, G., Fassari, A., Mingoli, A., Cirillo, B., D'Alterio, C., Brachini, G., Tancredi, M., Zambon, M., Aulicino, M., Sapienza, P., Liberatore, P., Scanu, A. M., Feo, C. F., Iacomino, A., Pelizzo, P., Rossi, S., Vigna, S. A., Grossi, U., Grillo, V., Agnes, A., Schena, C. A., Marincola, G., Oddi, A., Perotti, B., Mario, V., Perri, P., Zazza, S., Aversano, A., Scala, D., Di Lauro, K., Leongito, M., Piccirillo, M., Patrone, R., Capuzzolo, S., Vignotto, C., Bao, Q. R., Giuseppe, C., Angarano, E., Marino, F., Pezzolla, F., Gigante, G., Magistro, C., Crippa, J., Maspero, M., Carnevali, P., Trapani, R., Zonta, S., Agostinelli, L., Vittori, L., Romeo, L., Doria, E., Farnesi, F., Danna, R., Andolfi, E., Pellicano', G. A., Angelini, M., Scricciolo, M., Zanframundo, C., Ciulli, C., Ripamonti, L., Cigagna, L., Oldani, M., Larcinese, A., Rossi, D., Picone, E., Crescentini, G., Marano, A., Migliore, M., Giuffrida, M. C., Palagi, S., Testa, V., Borrello, A., Lucarini, A., Garofalo, E., Canali, G., Orlandi, P., Nervegna, F., Marchegiani, F., Damoli, I., Licata, A., Trovato, C., Alicata, F., Sardo, F., Milazzo, M., Randisi, B., Dominici, D. M., Sartarelli, L., Zanni, M., Pisanu, A., Soddu, C., Delogu, D., Erdas, E., Campus, F., Cappellacci, F., Casti, F., Marcialis, J., Atzeni, J., Podda, M. G., Sensi, B., Franceschilli, M., Bellato, V., Cannavera, A., Putzu, G., di Mola, F. F., Picardi, B., Solinas, L., Loponte, M., Rossi del Monte, S., Di Martino, C., Linari, C., Spagni, G., Capezzuoli, L., Tirloni, L., Nelli, T., Caridi, A., Elter, C., Camassa, M., D'Amico, S., Bargellini, T., Incollingo, P., Montuori, M., Maffione, F., Romano, L., Valiyeva, S., Spoletini, D., Menegon Tasselli, F., Sciaudone, G., Selvaggi, L., Menna, M. P., De Paola, G., Fulginiti, S., Truskovs, A., Weiss, C., Saknitis, G., Rauscher, J. T. R., Larnovskis, J., Jeyarajan-Davidsson, M., Nitisa, D., Gille, N., Reiser, S. C., Roshan, M. H. K., Leseman, C., Chen, J., van Dalen, A. S., Top, C., Detering, R., Matos, C., Silva, C., Pinto, D., Mendes, J., Couto, J., Leite, M., Velez, C., Damasio Cotovio, M., Cinza, A. M., Pedroso de Lima, R., Boyle, E., Yang, H. W., Banerjee, I., Rahmat, S., Afzal, Z., Reid, C., Dumitrascu, F., Croyle, J. A., Gressmann, K., Cullen, N., Graham, A., Nasehi, A., Montano King, C., Martin, B., Stokell, C., Sanderson, N., Farnan, R., Jassim, S., Chan, B., Chua Vi Long, K., Kaka, N., Pandey, S., Neo, W. X., Chitul, A., Bezede, C., Cincilei, D., David, A., Blaga, M., Blaga, S. N., Fagarasan, V., Khetagurova, M., Rodimov, S., Kapustina, A., Mekhralyzade, A., Zabiyaka, M., Jankovic, U., Cuk, V., Hajska, M., Dubovsky, M., Hrosova, M., Ferancikova, N., Camarero Rodriguez, E., Laguna Alcantara, F., Adarraga, J., Jezieniecki, C., Ruiz Soriano, M., Gomez Sanz, T., Suarez, A., Sanchez Garcia, C., Cifrian Canales, I., Llosa Perez, J., Merayo, M., Urbieta, A., Gegundez Simon, A., Tone, J. F., Gazo Martinez, J., Vicario Bravo, M., Chavarrias, N., Gil Catalan, A., Oseira, A., Villalonga, B., Jeri, S., Perez Calvo, J., Nogues, A., Cros, B., Yanez, C., Utrilla Fornals, A., Roldon Golet, M., Colsa, P., Gimenez Maurel, T., Axmarker, T., Chevallay, M., Pham, T. V., Sel, E. K., Atar, C., Aba, M., Sarkin, M., Akkaya, Y. M., Durmaz, A. G., Gullu, H. F., Boga, A., Aktas, A., Bakar, B., Demirel, M. T., Hysejni, X., Taser, M., Guzel, O. R., Bozbiyik, O., Ozen, D., Olmez, M., Uyar, B., Gulcek, E., Kayacan, G. S., Atici, N., Gul, O. F., Altiner, S., Ibis, B., Altunsu, S., Banaz, T., Diler, C., Demirbas, I., Usta, M. A., Erkul, O., Orman, R., Salih, S., Utkan, N. Z., Acil, C., Ozgur, E., Maddahali, M., Turhan, A. B., Eskici, A. B., Ular, B., Dogru, M., Ozturk, O. U., Arslan, E. R., Panahi Sharif, A., Dikmen, E., Ates, J., Bircan, R., Cavus, T., Sever, A. E., Balak, B., Duman, E., Altay, L., Emanet, O., Cullen, F., Tan, J. Y., Nathan, A., Rottenberg, A., Williams, C. Y., Mitrofan, C. G., Xu, D., Bawa, J. H., Morris, P., Gordon, D., Richmond, G., Hui, J. C., Ighomereho, O., Rocks, R., Mccabe, S., Fitzpatrick, A., Nicoletti, J., Auterson, L., Darrah, N., Soh, V. W. Y., Ong, C. S., Utukuri, M., Gallagher, C., Stuart, L. M., Hipolito, M., Douglas, N., Ghazal, R., Parris, G., Catchpole, J., Bryden, M., Jamal, S., Karim, Z., Lyon-Dean, C., Rowley, G., Lee, K. S., Whitehurst, O., Mirza, A., Sheikh, F., Yousaf, H., Bilbao, J., Sinclair, R., Takar, S., Kressel, H., Chan, V., Schack, K., Osborne, R., Baldemor, S., Smyth, S., Gilmour, S., Ting, A., Bozonelou, I., Saunders, P., Qhaireel Anwar, Q. A., Tirimanna, R., Jauhari, S., Gardener, A., Walker, B., Wenban, C., Reddy, H., Conway-Jones, R., Loganathan, S., Clynch, A., James, C., Matey, E., Cameron, F., Roberts, W., Gicquel, A., Milliken, C., Forbes, J., Rubinchik, P., Azmi, A., Hawkes, C., Cornett, L., Adarkwah, P., Mcconville, R., O'Hara, S., Tijare, C., Parkes, J., Yao, L., Ahmad, R., Shafiq, U., Mhaisalkar, A., Gurung, A., de Stadler, K., Elias, S., Thomas, T., Madras, A., Jani, A., Daler, H. K., Tong, K. S., Sundaralingam, S. S., Szal, A., Khan, A., O'Sullivan, C., Baker, E., Joseph-Gubral, J., Hadley, E., Trivedi, R., Igwelaezoh, E., Barton, H., Allison, W., Hurst, W., Alam, F., Parkes, I., Jamshaid, M., Azizan, N., Burgher, T., Afzal, A., Eltilib, I., Zahid, M., Sadiq, O., Lloyd, A., Ho, R., Brazukas, A., Li, C. H., Kamdar, M., Mohamed Nazeer, M. N., Mighiu, A., Kim, D., Wilkins, L., Kuo, L., Rafe, T., Maduka, D., Cheema, H., Farag, K., Abdellatif, M., Nzewi, R., Kruczynska, A., Grasselli, H., Yousuff, M., Bassi, R., Mann, A. K., Chopra, J., Shaikh, M., Sa, D. S., Tsimplis, V., Ghanchi, A., Skene, E., Asim, K., Zaheer, M., Chan, S., Dalton, H., Gibbons, K., Adderley, O., Chukwujindu, I., Jayasuriya, I., Sivanu, K., Borumand, M., Chick, G., Bridges, I., Tomlin, J., Mckenna, J., Nandra, N., Grieco, C., Quek, F. F., Mercer, R., Brankin-Frisby, T., Sattar, A., Aslam, A., Edelsten, E., Shafi, S., Kouli, T., Ford, V., Gurung, F., Fernandes, M., Deader, N., Ponniah, R., Jamieson, S., Davies, A., Taubwurcel, J., Aung, M. T., Desai, R., Begum, S., Jamadar, T., Kangatharan, A., Rzeszowski, B., Ho, C., Yap, S. H. K., Prendergast, M., Sethi, R., Duku, A., Lowe, C., Bray, J., Ghobrial, M., Nichita, V., Wagstaff, A., Rengasamy, E., Abu Hassan, F., Mahmood, H., Savill, N., Shah, S., Almeida, T., Edwards, A., Catchpole, B., Halford, Z., Carmichael, A., Alsusa, H., Boyd, M., Williams, J., Feyi-Waboso, J., Patel, M., Zeidan, Z., Bailey, E., Bapty, J., Brazkiewicz, M., Tremlett, A., Pringle, H., Mankal, S., Chung, W., Parry-Jones, E., Anderson, K., Mcforrester, A., Stanley, A., Hoather, A., Wise, H., Laid, I., Scriven, J., Braniste, A., Wilson, A., Le Blevec, L., Pakunwanich, N., Evans, N., Chong, H. L., White, C., Hunter, J., Haque, M., Vanalia, P., Murdoch, S., Choudhary, T., Mccann, A., Harun, A., Shah, H., Hunt, S., Shafiq, Y., Bickley-Morris, E., Emms, L., Dare, M., Akula, Y., Deliyannis, E., Mayes, F., Ellacott, M., Zagorac, Z., Farren, A., Manning, C., Hughed, C., Stewart, E. G., Lim, K. H., Chohan, N., Thaker, A., Thompson, B., Ahari, D., Burdekin, E., Okwu, U., Akintunde, A., Lhaf, F., Douthwaite, J., Govindan, R., Leelamanthep, S., Gull, E., Wright, F., Dundas, L., Mackdermott, N., Burchi-Khairy, T., Campbell, I., Walsh, J., Yeo, J. Y., Meehan, S., Banerjee, D., Fu, M., Kawka, M., Ali, T., Hussain, Z., Thomas, C., Ahmad, H., Moroney, J., Yick, C., Risquet, R., Ntuiabane, D., Shimato, M., Khan, M., Ilangovan, S., Vaselli, N. M., Smithers, R., Uhanowita Marage, R., Valnarov-Boulter, A., Kayran, J., Banerjee, M., Parekh-Hill, N., Hooper, A., Bowen, J., Jagdish, R., Mcquoid, C., Khan, N., O'Hare, R., Jeffery, S., Zahid, A., Elsworth, C., Walter, L., Dhillon, S., Rao, S., Anthony, A., Ashaye, A., Phillips, N., Faderani, R., Pengelly, S., Choi, S., Kwak, S. Y., Lau, Y. H. L., Bagheri, K., Ong, D. Y. C., Kerr, E., Falconer, K., Clancy, N., Douglas, S., Zhang, Y., Greenfield, F., Mutanga, I., Mcalinden, J., Willis, L., Adefolaju, A., Agarwal, H., Barter, R., Harris, G., Spencer, G., Lee, M. W., Vadiveloo, V. T., Herbert, G., Patel, R., Shah, M., El Falaha, S., Wong, C., Soare, C., Akram, J., Bozhkova, L., Ma, Y., Vo, U. G., Tan, H. W. N., Leto, L., Kamal, M. A., Hadzhieva, E., Krastev, P., Tonchev, P., Kokkinos, G., Pozotou, I., Sabbagh, D., Votava, J., St, F., Koliakos, N., Tsaparas, P., Zografos, G., Mantas, D., Tsourouflis, G., Fradelos, E., Trigiante, G., Labellarte, G., Resta, G., Capelli, G., D'Amore, A., Verlingieri, V., Campagnaro, T., Maffioli, A., Viscosi, F., De Lucia, C., Meneghini, S., Fancellu, A., Colella, M., Biondi, A., De Peppo, V., Pace, U., Albino, V., Gattulli, D., Piangerelli, A., Kalivaci, D., Sisto, G., Mazzola, M., Caneparo, A., Lunghi, E. G., Nespoli, L. C., Angrisani, M., Langone, A., Gelarda, E., Virgilio, E., Angelini, E., Fornasier, C., Asero, S., Filippone, E., Frongia, F., Calo, P. G., Panaccio, P., Ipponi, P., Gili, S., Braccio, B., Tiesi, V., Stolcers, K., Kokaine, L., Novikovs, V., Capel, L., Bastiaenen, V., Heijmans, H., Henriques, S., Gan, S. Z., Ramanayake, H., Nolan, M., Temperley, H., Ciofic, E., Pop, B. A., Kurtenkov, M., Jovanovic, M., Vician, M., Egea Arias, P., Beltran de Heredia, J., Labalde Martinez, M., De Santiago Alvarez, I., Alvarez-Gallego, M., Rodriguez Artigas, J. M., Dwidar, O., Korkmaz, H. K., Eray, I. C., Meric, S., Aydin, R., Cetin, B., Karaca, B. E., Kuyumcu, O. F., Yuksel, E., Uprak, T. K., Karabulut, K., Kavukcu, E., Mansor, A., Hackett, R., Zammit-Maempel, M., Sabaratnam, R., Maan, A., Ferarrio, I., Dixon, L., Halai, H., Sethi, S., Nelson, L., Grassam-Rowe, A., Krishnan, E., Deeny, D., Mckeever, M., George Pandeth, A., Dhavala, P., Sreenivasan, S., Sundaram Venkatesan, G., Zhu, L., Atiyah, Z., Gregory, J., Morey, T., Seymour, Z., Holdsworth, L., Abdelmahmoud, S., Bourhill, J., Bisheet, G., Shaw, J., Kulkarni, K., Kumarakulasingam, P., Pillay, S., Al-Habsi, R., Kungwengwe, G., Richards, J., Davoudi, K., Ibrahim, B., Tailor, B., Zayed, M., Chen, F., Bailey, S., Sheefat, S., Nawaz, G., Pawar, R., Marsh, S., Sam, Z. H., Roy Bentley, S., Simpson, C., Hughes, J., Lim, Y., Ooi, R., Toh, W. H., Mannion, P., Lovett, A., Kincius, A., Hussein, S., Kirby, E., Beckett, R. G., Salmon, J., Glynn, T., Choo, S. Y., Lyons, S., Browne, D., Ravindran, W., Ahmad, S., Zhu, X., Mcnulty, J., Mccarthy, L., Ng, J., Karmally, Z., Mcteir, K., Hanna, M., Tan, E., Namdeo, S., Schembri, R., and Pusey, E.
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Adult ,Elective Surgical Procedure ,Aged ,Cohort Studies ,Drainage ,Elective Surgical Procedures ,Female ,Humans ,Postoperative Complications ,Prospective Studies ,Surgical Wound Infection ,Colorectal Surgery ,drain ,intrabdominal ,Adult, Aged, Cohort Studies, Colorectal Surgery, Drainage, Elective Surgical Procedures, Female, Humans, Postoperative Complications, Prospective Studies, Surgical Wound Infection ,Settore MED/18 ,Settore MED/18 - Chirurgia Generale ,Prospective Studie ,Surgery ,Postoperative Complication ,Cohort Studie ,drain, intrabdominal ,Human - Abstract
Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien–Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P < 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk.
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- 2022
6. Hemiglans resurfacing for the treatment of small, superficial penile cancer or precancerous lesions
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Cirigliano, L., Capece, M., Di Giovanni, L., di Giovanni, A., Giordano, A., D’Alterio, C., Napolitano, L., Mirone, C., La Rocca, R., Creta, M., Palmieri, A., Imbimbo, C., Mirone, V., Cirigliano, L., Capece, M., Di Giovanni, L., di Giovanni, A., Giordano, A., D’Alterio, C., Napolitano, L., Mirone, C., La Rocca, R., Creta, M., Palmieri, A., Imbimbo, C., and Mirone, V.
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Urology - Published
- 2021
7. Extracorporeal shock wave therapy in association with bromelain and escin for managing patients affected by chronic pelvic pain syndrome: Results of a prospective, randomized clinical trial
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Palmieri, A., primary, Di Luise, L., additional, D'Alterio, C., additional, Cirigliano, L., additional, Di Giovanni, A., additional, Capece, M., additional, and Cai, T., additional
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- 2022
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8. High Expression of CXCR4 - CXCR7 - CXCL12 Predicts Poor Survival after Up-Front Resection of Pancreatic Adenocarcinoma
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Giardino, A., primary, D'Alterio, C., additional, Scala, S., additional, Frigerio, I., additional, Girelli, R., additional, Regi, P., additional, Scopelliti, F., additional, Allegrini, V., additional, and Butturini, G., additional
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- 2022
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9. 1796P CXCL12-loaded-hydrogel (CLG) based 'pseudo niche': A new device for CTCs capturing and characterization
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Portella, L., primary, Guardascione, G., additional, Bertolini, G., additional, Ieranò, C., additional, D'Alterio, C., additional, Rea, G., additional, Santagata, S., additional, Trotta, A.M., additional, Camerlingo, R., additional, Scarpa, E., additional, Cecere, S.C., additional, Ottaiano, A., additional, Palumbo, G., additional, Morabito, A., additional, Pacelli, R., additional, Pignata, S., additional, and Scala, S., additional
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- 2021
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10. Nonisothermal reactors for the production of pure water from peritoneal dialysis waste waters
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DIANO, N., ETTARI, G., GRANO, V., GAETA, F. S., ROSSI, S., BENCIVENGA, U., DʼALTERIO, C., RUOCCO, G., MITA, L., DE SANTO, N. G., CANCIGLIA, P., and MITA, D. G.
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- 2007
11. Basal NK activity and early Treg function inhibition predicts Nivolumab responsiveness in metastatic renal cancer patients (REVOLUTION) trial
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Santagata, S., primary, Trotta, A.M., additional, Rea, G., additional, Napolitano, M., additional, D’Alterio, C., additional, Napoli, M Di, additional, Rossetti, S., additional, Pignata, S., additional, and Scala, S., additional
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- 2019
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12. SC232 - Hemiglans resurfacing for the treatment of small, superficial penile cancer or precancerous lesions
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Cirigliano, L., Capece, M., Di Giovanni, L., di Giovanni, A., Giordano, A., D’Alterio, C., Napolitano, L., Mirone, C., La Rocca, R., Creta, M., Palmieri, A., Imbimbo, C., and Mirone, V.
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- 2021
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13. A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients
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D'Alterio C, Avallone A, Tatangelo F, Delrio P, Pecori B, Cella L, Pelella A, Bianco F, Silvestro L, Napolitano M, Iaffaioli RV, D'ARMIENTO, FRANCESCO PAOLO, CARLOMAGNO, Chiara, PACELLI, ROBERTO, SCALA, STEFANIA, D'Alterio, C, Avallone, A, Tatangelo, F, Delrio, P, Pecori, B, Cella, L, Pelella, A, D'Armiento, FRANCESCO PAOLO, Carlomagno, Chiara, Bianco, F, Silvestro, L, Pacelli, Roberto, Napolitano, M, Iaffaioli, Rv, and Scala, Stefania
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predictive factor ,prognosis ,rectal cancer - Abstract
Despite the optimization of the local treatment of advanced rectal cancer (LARC), combination of preoperative chemoradiotherapy (CRT) and surgery, approximately one third of patients will develop distant metastases. Since the chemokine receptor CXCR4 has been implicated in metastasis development and prognosis in colorectal cancer, the role of the entire axis CXCR4-CXCL12-CXCR7 was evaluated to identify high relapse risk rectal cancer patients. Tumor specimens of 68 LARC patients undergoing surgery after neoadjuvant-CRT were evaluated for CXCR4, CXCR7, and CXCL12 expression through immunohistochemistry. Multivariable prognostic model was developed using classical prognostic factors along with chemokine receptor expression profiles. High CXCR4 correlated with a shorter relapse-free survival (RFS) (p = 0.0006) and cancer specific survival (CSS) (p = 0.0004). Concomitant high CXCR4-negative/low CXCR7 or high CXCR4-negative/low CXCL12 significantly impaired RFS (p = 0.0003 and p = 0.0043) and CSS (p = 0.0485 and p = 0.0026). High CXCR4/N+ identified the worst prognostic category for RFS (p < 0.0001) and CSS (p = 0.0003). The optimal multivariable predictive model for RFS was a five-variable model consisting of gender, pT stage, N status, CXCR4, and CXCR7 (AUC = 0.92, 95% CI = 0.77-0.98). The model is informative and supportive for adjuvant treatment and identifies CXCR4 as a new therapeutic target in rectal cancer.
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- 2014
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14. Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12)
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Di Maro S., Trotta A.M., Brancaccio D., Di Leva F.S., La Pietra V., Ierano C., Napolitano M., Portella L., D'Alterio C., Siciliano R.A., Sementa D., Tomassi S., Carotenuto A., Novellino E., Scala S., and Marinelli L.
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PHARMACOKINETICS ,Chemokine - Abstract
We previously reported the discovery of a CXCL12-mimetic cyclic peptide (2) as a selective CXCR4 antagonist showing promising in vitro and in vivo anticancer activity. However, further development of this peptide was hampered by its degradation in biological fluids as well as by its low micromolar affinity for the receptor. Herein, extensive chemical modifications led to the development of a new analogue (10) with enhanced potency, specificity, and plasma stability. A combined approach of Ala-amino acid scan, NMR, and molecular modeling unraveled the reasons behind the improved binding properties of 10 vs 2. Biological investigations on leukemia (CEM) and colon (HT29 and HCT116) cancer cell lines showed that 10 is able to impair CXCL12-mediated cell migration, ERK-phosphorylation, and CXCR4 internalization. These outcomes might pave the way for the future preclinical development of 10 in CXCR4 overexpressing leukemia and colon cancer.
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- 2016
15. Longitudinal evaluation with High Frequency Ultrasound imaging of response to CXCR4 new cyclic peptide antagonist with conventional chemotherapy in colorectal cancer mice model
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Greco, A., D'Alterio, C., Auletta, L., Albanese, S., Napolitano, M., Portella, L., Santagata, S., Ierano, C., Brunetti, A., Scala, S., and Zannetti, A.
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CXCR4 ,colorectal cancer mice model - Published
- 2015
16. High Frequency Ultrasound for the development of an Orthotopic mouse model of Human Follicular Thyroid Carcinoma
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Albanese, S., Zannetti, L. Auletta A., Di Maro, G., Mirabelli, P., D’Alterio, C., Salvatore, G., Soricelli, A., Salvatore, M., and Greco, A.
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- 2015
17. Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015.
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Nanda, VGY, Peng, W, Hwu, P, Davies, MA, Ciliberto, G, Fattore, L, Malpicci, D, Aurisicchio, L, Ascierto, PA, Croce, CM, Mancini, R, Spranger, S, Gajewski, TF, Wang, Y, Ferrone, S, Vanpouille-Box, C, Wennerberg, E, Pilones, KA, Formenti, SC, Demaria, S, Tang, H, Fu, Y-X, Dummer, R, Puzanov, I, Tarhini, A, Chauvin, J-M, Pagliano, O, Fourcade, J, Sun, Z, Wang, H, Sanders, C, Kirkwood, JM, Chen, T-HT, Maurer, M, Korman, AJ, Zarour, HM, Stroncek, DF, Huber, V, Rivoltini, L, Thurin, M, Rau, T, Lugli, A, Pagès, F, Camarero, J, Sancho, A, Jommi, C, de Coaña, YP, Wolodarski, M, Yoshimoto, Y, Gentilcore, G, Poschke, I, Masucci, GV, Hansson, J, Kiessling, R, Scognamiglio, G, Sabbatino, F, Marino, FZ, Anniciello, AM, Cantile, M, Cerrone, M, Scala, S, D’alterio, C, Ianaro, A, Cirin, G, Liguori, G, Bott, G, Chapman, PB, Robert, C, Larkin, J, Haanen, JB, Ribas, A, Hogg, D, Hamid, O, Testori, A, Lorigan, P, Sosman, JA, Flaherty, KT, Yue, H, Coleman, S, Caro, I, Hauschild, A, McArthur, GA, Sznol, M, Callahan, MK, Kluger, H, Postow, MA, Gordan, R, Segal, NH, Rizvi, NA, Lesokhin, A, Atkins, MB, Burke, MM, Ralabate, A, Rivera, A, Kronenberg, SA, Agunwamba, B, Ruisi, M, Horak, C, Jiang, J, Wolchok, J, Liszkay, G, Maio, M, Mandalà, M, Demidov, L, Stoyakovskiy, D, Thomas, L, de la Cruz-Merino, L, Atkinson, V, Dutriaux, C, Garbe, C, Wongchenko, M, Chang, I, Koralek, DO, Rooney, I, Yan, Y, Dréno, B, Sullivan, R, Patel, M, Hodi, S, Amaria, R, Boasberg, P, Wallin, J, He, X, Cha, E, Richie, N, Ballinger, M, Smith, DC, Bauer, TM, Wasser, JS, Luke, JJ, Balmanoukian, AS, Kaufman, DR, Zhao, Y, Maleski, J, Leopold, L, Gangadhar, TC, Long, GV, Michielin, O, VanderWalde, A, Andtbacka, RHI, Cebon, J, Fernandez, E, Malvehy, J, Olszanski, AJ, Gause, C, Chen, L, Chou, J, Stephen Hodi, F, Brady, B, Mortier, L, Hassel, JC, Rutkowski, P, McNeil, C, Kalinka-Warzocha, E, Lebbé, C, Ny, L, Chacon, M, Queirolo, P, Loquai, C, Cheema, P, Berrocal, A, Eizmendi, KM, Bar-Sela, G, Hardy, H, Weber, JS, Grob, J-J, Marquez-Rodas, I, Schmidt, H, Briscoe, K, Baurain, J-F, Wolchok, JD, Pinto, R, De Summa, S, Garrisi, VM, Strippoli, S, Azzariti, A, Guida, G, Guida, M, Tommasi, S, Jacquelot, N, Enot, D, Flament, C, Pitt, JM, Vimond, N, Blattner, C, Yamazaki, T, Roberti, M-P, Vetizou, M, Daillere, R, Poirier-Colame, V, la Semeraro, M, Caignard, A, Slingluff, CL, Sallusto, F, Rusakiewicz, S, Weide, B, Marabelle, A, Kohrt, H, Dalle, S, Cavalcanti, A, Kroemer, G, Di Giacomo, AM, Wong, P, Yuan, J, Umansky, V, Eggermont, A, Zitvogel, L, Anna, P, Marco, T, Stefania, S, Francesco, M, Mariaelena, C, Gabriele, M, Antonio, AP, Franco, S, Roberti, MP, Enot, DP, Semeraro, M, Jégou, S, Flores, C, Kwon, BS, Anderson, AC, Borg, C, Aubin, F, Ayyoub, M, De Presbiteris, AL, Cordaro, FG, Camerlingo, R, Fratangelo, F, Mozzillo, N, Pirozzi, G, Patriarca, EJ, Caputo, E, Motti, ML, Falcon, R, Miceli, R, Capone, M, Madonna, G, Mallardo, D, Carrier, MV, Panza, E, De Cicco, P, Armogida, C, Ercolano, G, Botti, G, Cirino, G, Sandru, A, Blank, M, Balatoni, T, Olasz, J, Farkas, E, Szollar, A, Savolt, A, Godeny, M, Csuka, O, Horvath, S, Eles, K, Shoenfeld, Y, Kasler, M, Costantini, S, Capone, F, Moradi, F, Berglund, P, Leandersson, K, Linnskog, R, Andersson, T, Prasad, CP, Nigro, CL, Lattanzio, L, Proby, C, Syed, N, Occelli, M, Cauchi, C, Merlano, M, Harwood, C, Thompson, A, Crook, T, Bifulco, K, Ingangi, V, Minopoli, M, Ragone, C, Pessi, A, Mannavola, F, D’Oronzo, S, Felici, C, Tucci, M, Doronzo, A, Silvestris, F, Ferretta, A, Guida, S, Maida, I, Cocco, T, Passarelli, A, Quaresmini, D, Franzese, O, Palermo, B, Di Donna, C, Sperduti, I, Foddai, M, Stabile, H, Gismondi, A, Santoni, A, Nisticò, P, Sponghini, AP, Platini, F, Marra, E, Rondonotti, D, Alabiso, O, Fierro, MT, Savoia, P, Stratica, F, Quaglino, P, Di Monta, G, Corrado, C, Di Marzo, M, Ugo, M, Di Cecilia, ML, Nicola, M, Fusciello, C, Marra, A, Guarrasi, R, Baldi, C, Russo, R, Di Giulio, G, Faiola, V, Zeppa, P, Pepe, S, Gambale, E, Carella, C, Di Paolo, A, De Tursi, M, Marra, L, De Murtas, F, Sorrentino, V, Voinea, S, Panaitescu, E, Bolovan, M, Stanciu, A, Cinca, S, Botti, C, Aquino, G, Anniciello, A, Fortes, C, Mastroeni, S, Caggiati, A, Passarelli, F, Zappalà, A, Capuano, M, Bono, R, Nudo, M, Marino, C, Michelozzi, P, De Biasio, V, Battarra, VC, Formenti, S, Ascierto, ML, McMiller, TL, Berger, AE, Danilova, L, Anders, RA, Netto, GJ, Xu, H, Pritchard, TS, Fan, J, Cheadle, C, Cope, L, Drake, CG, Pardoll, DM, Taube, JM, Topalian, SL, Gnjatic, S, Nataraj, S, Imai, N, Rahman, A, Jungbluth, AA, Pan, L, Venhaus, R, Park, A, Lehmann, FF, Lendvai, N, Cohen, AD, Cho, HJ, Daniel, S, Hirsh, V, Nanda, VGY, Peng, W, Hwu, P, Davies, MA, Ciliberto, G, Fattore, L, Malpicci, D, Aurisicchio, L, Ascierto, PA, Croce, CM, Mancini, R, Spranger, S, Gajewski, TF, Wang, Y, Ferrone, S, Vanpouille-Box, C, Wennerberg, E, Pilones, KA, Formenti, SC, Demaria, S, Tang, H, Fu, Y-X, Dummer, R, Puzanov, I, Tarhini, A, Chauvin, J-M, Pagliano, O, Fourcade, J, Sun, Z, Wang, H, Sanders, C, Kirkwood, JM, Chen, T-HT, Maurer, M, Korman, AJ, Zarour, HM, Stroncek, DF, Huber, V, Rivoltini, L, Thurin, M, Rau, T, Lugli, A, Pagès, F, Camarero, J, Sancho, A, Jommi, C, de Coaña, YP, Wolodarski, M, Yoshimoto, Y, Gentilcore, G, Poschke, I, Masucci, GV, Hansson, J, Kiessling, R, Scognamiglio, G, Sabbatino, F, Marino, FZ, Anniciello, AM, Cantile, M, Cerrone, M, Scala, S, D’alterio, C, Ianaro, A, Cirin, G, Liguori, G, Bott, G, Chapman, PB, Robert, C, Larkin, J, Haanen, JB, Ribas, A, Hogg, D, Hamid, O, Testori, A, Lorigan, P, Sosman, JA, Flaherty, KT, Yue, H, Coleman, S, Caro, I, Hauschild, A, McArthur, GA, Sznol, M, Callahan, MK, Kluger, H, Postow, MA, Gordan, R, Segal, NH, Rizvi, NA, Lesokhin, A, Atkins, MB, Burke, MM, Ralabate, A, Rivera, A, Kronenberg, SA, Agunwamba, B, Ruisi, M, Horak, C, Jiang, J, Wolchok, J, Liszkay, G, Maio, M, Mandalà, M, Demidov, L, Stoyakovskiy, D, Thomas, L, de la Cruz-Merino, L, Atkinson, V, Dutriaux, C, Garbe, C, Wongchenko, M, Chang, I, Koralek, DO, Rooney, I, Yan, Y, Dréno, B, Sullivan, R, Patel, M, Hodi, S, Amaria, R, Boasberg, P, Wallin, J, He, X, Cha, E, Richie, N, Ballinger, M, Smith, DC, Bauer, TM, Wasser, JS, Luke, JJ, Balmanoukian, AS, Kaufman, DR, Zhao, Y, Maleski, J, Leopold, L, Gangadhar, TC, Long, GV, Michielin, O, VanderWalde, A, Andtbacka, RHI, Cebon, J, Fernandez, E, Malvehy, J, Olszanski, AJ, Gause, C, Chen, L, Chou, J, Stephen Hodi, F, Brady, B, Mortier, L, Hassel, JC, Rutkowski, P, McNeil, C, Kalinka-Warzocha, E, Lebbé, C, Ny, L, Chacon, M, Queirolo, P, Loquai, C, Cheema, P, Berrocal, A, Eizmendi, KM, Bar-Sela, G, Hardy, H, Weber, JS, Grob, J-J, Marquez-Rodas, I, Schmidt, H, Briscoe, K, Baurain, J-F, Wolchok, JD, Pinto, R, De Summa, S, Garrisi, VM, Strippoli, S, Azzariti, A, Guida, G, Guida, M, Tommasi, S, Jacquelot, N, Enot, D, Flament, C, Pitt, JM, Vimond, N, Blattner, C, Yamazaki, T, Roberti, M-P, Vetizou, M, Daillere, R, Poirier-Colame, V, la Semeraro, M, Caignard, A, Slingluff, CL, Sallusto, F, Rusakiewicz, S, Weide, B, Marabelle, A, Kohrt, H, Dalle, S, Cavalcanti, A, Kroemer, G, Di Giacomo, AM, Wong, P, Yuan, J, Umansky, V, Eggermont, A, Zitvogel, L, Anna, P, Marco, T, Stefania, S, Francesco, M, Mariaelena, C, Gabriele, M, Antonio, AP, Franco, S, Roberti, MP, Enot, DP, Semeraro, M, Jégou, S, Flores, C, Kwon, BS, Anderson, AC, Borg, C, Aubin, F, Ayyoub, M, De Presbiteris, AL, Cordaro, FG, Camerlingo, R, Fratangelo, F, Mozzillo, N, Pirozzi, G, Patriarca, EJ, Caputo, E, Motti, ML, Falcon, R, Miceli, R, Capone, M, Madonna, G, Mallardo, D, Carrier, MV, Panza, E, De Cicco, P, Armogida, C, Ercolano, G, Botti, G, Cirino, G, Sandru, A, Blank, M, Balatoni, T, Olasz, J, Farkas, E, Szollar, A, Savolt, A, Godeny, M, Csuka, O, Horvath, S, Eles, K, Shoenfeld, Y, Kasler, M, Costantini, S, Capone, F, Moradi, F, Berglund, P, Leandersson, K, Linnskog, R, Andersson, T, Prasad, CP, Nigro, CL, Lattanzio, L, Proby, C, Syed, N, Occelli, M, Cauchi, C, Merlano, M, Harwood, C, Thompson, A, Crook, T, Bifulco, K, Ingangi, V, Minopoli, M, Ragone, C, Pessi, A, Mannavola, F, D’Oronzo, S, Felici, C, Tucci, M, Doronzo, A, Silvestris, F, Ferretta, A, Guida, S, Maida, I, Cocco, T, Passarelli, A, Quaresmini, D, Franzese, O, Palermo, B, Di Donna, C, Sperduti, I, Foddai, M, Stabile, H, Gismondi, A, Santoni, A, Nisticò, P, Sponghini, AP, Platini, F, Marra, E, Rondonotti, D, Alabiso, O, Fierro, MT, Savoia, P, Stratica, F, Quaglino, P, Di Monta, G, Corrado, C, Di Marzo, M, Ugo, M, Di Cecilia, ML, Nicola, M, Fusciello, C, Marra, A, Guarrasi, R, Baldi, C, Russo, R, Di Giulio, G, Faiola, V, Zeppa, P, Pepe, S, Gambale, E, Carella, C, Di Paolo, A, De Tursi, M, Marra, L, De Murtas, F, Sorrentino, V, Voinea, S, Panaitescu, E, Bolovan, M, Stanciu, A, Cinca, S, Botti, C, Aquino, G, Anniciello, A, Fortes, C, Mastroeni, S, Caggiati, A, Passarelli, F, Zappalà, A, Capuano, M, Bono, R, Nudo, M, Marino, C, Michelozzi, P, De Biasio, V, Battarra, VC, Formenti, S, Ascierto, ML, McMiller, TL, Berger, AE, Danilova, L, Anders, RA, Netto, GJ, Xu, H, Pritchard, TS, Fan, J, Cheadle, C, Cope, L, Drake, CG, Pardoll, DM, Taube, JM, Topalian, SL, Gnjatic, S, Nataraj, S, Imai, N, Rahman, A, Jungbluth, AA, Pan, L, Venhaus, R, Park, A, Lehmann, FF, Lendvai, N, Cohen, AD, Cho, HJ, Daniel, S, and Hirsh, V
- Abstract
MELANOMA BRIDGE 2015 KEYNOTE SPEAKER PRESENTATIONS Molecular and immuno-advances K1 Immunologic and metabolic consequences of PI3K/AKT/mTOR activation in melanoma Vashisht G. Y. Nanda, Weiyi Peng, Patrick Hwu, Michael A. Davies K2 Non-mutational adaptive changes in melanoma cells exposed to BRAF and MEK inhibitors help the establishment of drug resistance Gennaro Ciliberto, Luigi Fattore, Debora Malpicci, Luigi Aurisicchio, Paolo Antonio Ascierto, Carlo M. Croce, Rita Mancini K3 Tumor-intrinsic beta-catenin signaling mediates tumor-immune avoidance Stefani Spranger, Thomas F. Gajewski K4 Intracellular tumor antigens as a source of targets of antibody-based immunotherapy of melanoma Yangyang Wang, Soldano Ferrone Combination therapies K5 Harnessing radiotherapy to improve responses to immunotherapy in cancer Claire Vanpouille-Box, Erik Wennerberg, Karsten A. Pilones, Silvia C. Formenti, Sandra Demaria K6 Creating a T cell-inflamed tumor microenvironment overcomes resistance to checkpoint blockade Haidong Tang, Yang Wang, Yang-Xin Fu K7 Biomarkers for treatment decisions? Reinhard Dummer K8 Combining oncolytic therapies in the era of checkpoint inhibitors Igor Puzanov K9 Immune checkpoint blockade for melanoma: should we combine or sequence ipilimumab and PD-1 antibody therapy? Michael A. Postow News in immunotherapy K10 An update on adjuvant and neoadjuvant therapy for melanom Ahmad Tarhini K11 Targeting multiple inhibitory receptors in melanoma Joe-Marc Chauvin, Ornella Pagliano, Julien Fourcade, Zhaojun Sun, Hong Wang, Cindy Sanders, John M. Kirkwood, Tseng-hui Timothy Chen, Mark Maurer, Alan J. Korman, Hassane M. Zarour K12 Improving adoptive immune therapy using genetically engineered T cells David F. Stroncek Tumor microenvironment and biomarkers K13 Myeloid cells and tumor exosomes: a crosstalk for assessing immunosuppression? Veronica Huber, Licia Rivoltini K14 Update on the SITC biomarker taskforce: progress and challenges Magdalena Thurin World-wide immunosc
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- 2016
18. 1906P - Basal NK activity and early Treg function inhibition predicts Nivolumab responsiveness in metastatic renal cancer patients (REVOLUTION) trial
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Santagata, S., Trotta, A.M., Rea, G., Napolitano, M., D’Alterio, C., Napoli, M Di, Rossetti, S., Pignata, S., and Scala, S.
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- 2019
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19. Differential role of CD133 and CXCR4 in renal cellcarcinoma
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D'Alterio C, Cindolo L, Portella L, Polimeno M, Consales C, Riccio A, Cioffi M, Franco R, Chiodini P, Cartenì G, Mirone V, Longo N, Marra L, Perdonà S, Claudio L, Falsaperla M, Puglisi M, Martignoni G, Ficarra V, Castello G, Scala S., MASCOLO, MASSIMO, STAIBANO, STEFANIA, D'Alterio, C, Cindolo, L, Portella, L, Polimeno, M, Consales, C, Riccio, A, Cioffi, M, Franco, R, Chiodini, P, Cartenì, G, Mirone, V, Longo, N, Marra, L, Perdonà, S, Claudio, L, Mascolo, Massimo, Staibano, Stefania, Falsaperla, M, Puglisi, M, Martignoni, G, Ficarra, V, Castello, G, and Scala, S.
- Abstract
The chemokine receptor CXCR4 and CD133, putative stem cell markers, were previously described in renal cancer (RCC). To evaluate the biological and prognostic role of CD133 and CXCR4 in RCC the expression was evaluated through qPCR and immunoblotting in human renal cancer cell lines (786-O, A498, ACHN, CAKI-1, SN12C, TK10, UO31) and patients biopsies. Renal cancer cells and surgical biopsies expressed functional CXCR4 while CD133 was not detectable. CXCR4 and CD133 expression was then evaluated in 240 renal cancer patients through immunohistochemistry. CXCR4 and CD133 were low in 19.1% and 59.6%; intermediate in 20% and 17.9%; high in 60.8% and 22.5% of the cases, respectively. CXCR4 was overexpressed in tumours (p= 0.02), while CD133 was over expressed in healthy tissues (p= 0.04). Disease free survival Kaplan Meier plots suggest that prognosis is unfavourable for patients whose primary tumours express CXCR4 (p= 0.0199) but nor CD133 (p= 0.151) neither the concomitant CXCR4-CD133 (p=0.848) high expression affected prognosis. Analysis of prognostic factors suggests that age, clinical presentation, AJCC stage and CXCR4 had a significant prognostic value at the univariate analysis. The CXCR4 predictive ability was confirmed at the multivariate analysis while no prognostic role was identified for CD133.Thus concomitant CD133 and CXCR4 evaluation is not worth in RCC patient while the CXCR4 prognostic role encourage CXCR4 antagonists as promising therapeutic option.
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- 2010
20. NMR structure of peptide 2 targeting CXCR4
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Di Maro, S., primary, Trotta, A.M., additional, Brancaccio, D., additional, Di Leva, F.S., additional, La Pietra, V., additional, Ierano, C., additional, Napolitano, M., additional, Portella, L., additional, D'Alterio, C., additional, Siciliano, R.A., additional, Sementa, D., additional, Tomassi, S., additional, Carotenuto, A., additional, Novellino, E., additional, Scala, S., additional, and Marinelli, L., additional
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- 2016
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21. NMR structure of peptide 10 targeting CXCR4
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Di Maro, S., primary, Trotta, A.M., additional, Brancaccio, D., additional, Di Leva, F.S., additional, La Pietra, V., additional, Ierano, C., additional, Napolitano, M., additional, Portella, L., additional, D'Alterio, C., additional, Siciliano, R.A., additional, Sementa, D., additional, Tomassi, S., additional, Carotenuto, A., additional, Novellino, E., additional, Scala, S., additional, and Marinelli, L., additional
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- 2016
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22. IN VITRO AND IN VIVO FUNCTIONAL CHARACTERIZATION OF NEW CYCLE-PEPTIDES INHIBITORS FOR C-X-C CHEMOKINE RECEPTOR-4 (CXCR4)
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Portella L, Napolitano M, Consales C, DAlterio C, Polimero M, Cioffi M, Vitale RM, Amodeo P, De Luca S, and Monfregola L
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- 2009
23. DESIGN, SYNTHESIS AND FUNCTIONAL CHARACTERIZATION OF NEW PEPTIDES
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Portella L., Mauro F., Napolitano M., Ieranò C., D'Alterio C., VitaleR.M., Amodeo P., De Luca S., Monfregola L., Castello G., and Scala S.
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- 2008
24. A CXCR4 point mutation (G574A) detected in human cancer cell lines impaired tumor growth and affected ADM3100 sensitivity
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Ieranò C, Giuliano P, D'alterio C, Cioffi M, Portella L, Calemma R, Napolitano M, Barbieri A, Arra C, Liguori G, Franco R, Palmieri G, Castello G, and Scala S.
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- 2008
25. FUNCTIONAL ASSAYS TO TEST CXCR4-INTERACTING NEW SYNTHESIZED PEPTIDIC
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Napolitano M., Mauro F., Portella L., De Luca S., Amodeo P., Vitale R.M., Ciarmiello A., DAlterio C., Mettivier V., Scala S., and Castello G.
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- 2007
26. 317 Prognostic influence of chromophobe subtype and sarcomatoid dedifferentiation in patients with renal cell carcinoma and impact of clinical and histopathological parameters on disease-specific survival in patients with collecting duct renal cell carcinoma (CDRCC): Results of comprehensive analyses of the CORONA and SATURN databases and development of a disease-specific risk-model for CDRCC patients
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Brookman-May, S.D., primary, Ficarra, V., additional, Shariat, S., additional, Zigeuner, R., additional, Chromecki, T., additional, Cindolo, L., additional, Gunia, S., additional, Aziz, A., additional, Otto, W., additional, Pahernik, S., additional, Chun, F., additional, Becker, A., additional, Simeone, C., additional, Longo, N., additional, Zucchi, A., additional, Stabiano, S., additional, D'Alterio, C., additional, Gilfrich, C., additional, Schips, L., additional, De Cobelli, O., additional, Joniau, S., additional, Waidelich, R., additional, Pichler, M., additional, Rocco, B., additional, Tubaro, A., additional, Feciche, B., additional, Truss, M., additional, Dalpiaz, O., additional, Zastrow, S., additional, Wirth, M., additional, Santiago, Martin M., additional, Hoschke, B., additional, Stief, C., additional, and May, M., additional
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- 2014
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27. High CXCR4 Expression Correlates with Sunitinib Poor Response in Metastatic Renal Cancer
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D'Alterio, C., primary, Portella, L., additional, Ottaiano, A., additional, Rizzo, M., additional, Carteni, G., additional, Pignata, S., additional, Facchini, G., additional, Perdona, S., additional, Di Lorenzo, G., additional, Autorino, R., additional, Franco, R., additional, La Mura, A., additional, Nappi, O., additional, Castello, G., additional, and Scala, S., additional
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- 2012
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28. Concomitant CXCR4 and CXCR7 Expression Predicts Poor Prognosis in Renal Cancer
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D'Alterio, C., primary, Consales, C., additional, Polimeno, M., additional, Franco, R., additional, Cindolo, L., additional, Portella, L., additional, Cioffi, M., additional, Calemma, R., additional, Marra, L., additional, Claudio, L., additional, Perdona, S., additional, Pignata, S., additional, Facchini, G., additional, Carteni, G., additional, Longo, N., additional, Pucci, L., additional, Ottaiano, A., additional, Costantini, S., additional, Castello, G., additional, and Scala, S., additional
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- 2010
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29. Abstract B50: Design, synthesis, and functional characterization of new cycle-peptides inhibitors for C-X-C chemokine receptor-4
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Portella, L., primary, Napolitano, M., additional, Consales, C., additional, Polimeno, M. N., additional, D'Alterio, C., additional, Arra, C., additional, Vitale, R., additional, Amodeo, P., additional, De Luca, S., additional, Monfregola, L., additional, Castello, G., additional, and Scala, S., additional
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- 2010
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30. 1022 CXCR4 EXPRESSION AFFECTS DISEASE FREE SURVIVAL IN RENAL CELL CARCINOMA (RCC)
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Cindolo, L., primary, D'Alterio, C., additional, Franco, R., additional, Polimeno, M.N., additional, Riccio, A., additional, Chiodini, P., additional, Cartenì, G., additional, Longo, N., additional, Mirone, V., additional, Pucci, L., additional, Marra, L., additional, Gallo, A., additional, Mascolo, M., additional, Staibano, S., additional, Salzano, L., additional, Falsaperla, M., additional, Iaffaioli, R.V., additional, Castello, G., additional, and Scala, S., additional
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- 2009
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31. High Frequency Ultrasound for the development of an Orthotopic mouse model of Human Follicular Thyroid Carcinoma
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Albanese, S., Auletta, L., Zannetti, A., Di Maro, G., Mirabelli, P., D Alterio, C., Salvatore, G., Andrea Soricelli, Salvatore, M., and Greco, A.
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High Frequency Ultrasound ,animal model Thyroid
32. Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients
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Napolitano M, D'Alterio C, Cardone E, Am, Trotta, Pecori B, Rega D, Pace U, Scala D, Scognamiglio G, Tatangelo F, Cacciapuoti C, Roberto Pacelli, Delrio P, and Scala S
33. Biological Role of Tumor/Stromal CXCR4-CXCL12-CXCR7 in MITO16A/MaNGO-OV2 Advanced Ovarian Cancer Patients
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Crescenzo D’Alterio, Anna Spina, Laura Arenare, Paolo Chiodini, Maria Napolitano, Francesca Galdiero, Luigi Portella, Vittorio Simeon, Simona Signoriello, Francesco Raspagliesi, Domenica Lorusso, Carmela Pisano, Nicoletta Colombo, Gian Franco Zannoni, Nunzia Simona Losito, Rossella De Cecio, Giosuè Scognamiglio, Daniela Califano, Daniela Russo, Valentina Tuninetti, Maria Carmela Piccirillo, Piera Gargiulo, Francesco Perrone, Sandro Pignata, Stefania Scala, D'Alterio, C., Spina, A., Arenare, L., Chiodini, P., Napolitano, M., Galdiero, F., Portella, L., Simeon, V., Signoriello, S., Raspagliesi, F., Lorusso, D., Pisano, C., Colombo, N., Zannoni, G. F., Losito, N. S., De Cecio, R., Scognamiglio, G., Califano, D., Russo, D., Tuninetti, V., Piccirillo, M. C., Gargiulo, P., Perrone, F., Pignata, S., Scala, S., D'Alterio, C, Spina, A, Arenare, L, Chiodini, P, Napolitano, M, Galdiero, F, Portella, L, Simeon, V, Signoriello, S, Raspagliesi, F, Lorusso, D, Pisano, C, Colombo, N, Zannoni, G, Losito, N, De Cecio, R, Scognamiglio, G, Califano, D, Russo, D, Tuninetti, V, Piccirillo, M, Gargiulo, P, Perrone, F, Pignata, S, and Scala, S
- Subjects
Cancer Research ,CXCR4-CXCL12-CXCR7 axi ,ovarian cancer ,Oncology ,endocrine system diseases ,embryonic structures ,chemokine ,tumor microenvironment ,biological phenomena, cell phenomena, and immunity ,biological factors ,prognosi ,CXCR4-CXCL12-CXCR7 axis ,prognosis - Abstract
This study investigated the prognostic role of the CXCR4-CXCL12-CXCR7 axis in advanced epithelial ovarian cancer (EOC) patients receiving first-line treatment within the MITO16A/MaNGO-OV2 phase-IV trial. CXCR4-CXCL12-CXCR7 expression was evaluated in the epithelial and stromal component of 308 EOC IHC-stained tumor samples. The statistical analysis focused on biomarkers’ expression, their association with other variables and prognostic value. Zero-inflated tests, shrinkage, bootstrap procedures, and multivariable models were applied. The majority of EOC (75.0%) expressed CXCR4 and CXCR7, 56.5% expressed the entire CXCR4-CXCL12-CXCR7 axis, while only 4.6% were negative for CXCL12 and its cognate receptors, in regard to the epithelial component. Stromal CXCL12 and CXCR7, expressed in 11.2% and 65.5%, respectively, were associated with the FIGO stage. High CXCL12 in epithelial cancer cells was associated with shorter progression-free and overall survival. However, after adjusting for overfitting due to best cut-off multiplicity testing, the significance was lost. This is a wide-ranging, prospective study in which CXCR4-CXCL12-CXCR7 were systematically evaluated in epithelial and stromal components, in selected stage III-IV EOC. Although CXCL12 was not prognostic, epithelial expression identified high-risk FIGO stage III patients for PFS. These data suggest that it might be worth studying the CXCL12 axis as a therapeutic target to improve treatment efficacy in EOC patients.
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- 2022
34. A0435 - Extracorporeal shock wave therapy in association with bromelain and escin for managing patients affected by chronic pelvic pain syndrome: Results of a prospective, randomized clinical trial.
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Palmieri, A., Di Luise, L., D'Alterio, C., Cirigliano, L., Di Giovanni, A., Capece, M., and Cai, T.
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EXTRACORPOREAL shock wave therapy , *PELVIC pain , *CHRONIC pain , *BROMELIN , *CLINICAL trials , *SYNDROMES - Published
- 2022
- Full Text
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35. The Role of Testosterone in the Elderly: What Do We Know?
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Biagio Barone, Luigi Napolitano, Marco Abate, Luigi Cirillo, Pasquale Reccia, Francesco Passaro, Carmine Turco, Simone Morra, Francesco Mastrangelo, Antonio Scarpato, Ugo Amicuzi, Vincenzo Morgera, Lorenzo Romano, Francesco Paolo Calace, Savio Domenico Pandolfo, Luigi De Luca, Achille Aveta, Enrico Sicignano, Massimiliano Trivellato, Gianluca Spena, Carlo D’Alterio, Giovanni Maria Fusco, Raffaele Vitale, Davide Arcaniolo, Felice Crocetto, Barone, B., Napolitano, L., Abate, M., Cirillo, L., Reccia, P., Passaro, F., Turco, C., Morra, S., Mastrangelo, F., Scarpato, A., Amicuzi, U., Morgera, V., Romano, L., Calace, F. P., Pandolfo, S. D., De Luca, L., Aveta, A., Sicignano, E., Trivellato, M., Spena, G., D'Alterio, C., Fusco, G. M., Vitale, R., Arcaniolo, D., and Crocetto, F.
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Male ,Aging ,Depression ,Hormone Replacement Therapy ,Hypogonadism ,Organic Chemistry ,General Medicine ,Replacement therapy ,Metabolic syndrome ,Catalysis ,Computer Science Applications ,Inorganic Chemistry ,Erectile Dysfunction ,Humans ,Testosterone ,Physical and Theoretical Chemistry ,Bone density ,Molecular Biology ,Spectroscopy ,Human ,Aged - Abstract
Testosterone is the most important hormone in male health. Aging is characterized by testosterone deficiency due to decreasing testosterone levels associated with low testicular production, genetic factors, adiposity, and illness. Low testosterone levels in men are associated with sexual dysfunction (low sexual desire, erectile dysfunction), reduced skeletal muscle mass and strength, decreased bone mineral density, increased cardiovascular risk and alterations of the glycometabolic profile. Testosterone replacement therapy (TRT) shows several therapeutic effects while maintaining a good safety profile in hypogonadal men. TRT restores normal levels of serum testosterone in men, increasing libido and energy level and producing beneficial effects on bone density, strength and muscle as well as yielding cardioprotective effects. Nevertheless, TRT could be contraindicated in men with untreated prostate cancer, although poor findings are reported in the literature. In addition, different potential side effects, such as polycythemia, cardiac events and obstructive sleep apnea, should be monitored. The aim of our review is to provide an updated background regarding the pros and cons of TRT, evaluating its role and its clinical applicability in different domains.
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- 2022
36. Male Sexual Dysfunction and Infertility in Spinal Cord Injury Patients: State-of-the-Art and Future Perspectives
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Francesco Di Bello, Massimiliano Creta, Luigi Napolitano, Gianluigi Califano, Francesco Passaro, Simone Morra, Angelo di Giovanni, Giovanni Maria Fusco, Luigi Cirillo, Marco Abate, Vincenzo Morgera, Gianluigi Cacace, Luigi De Luca, Gianluca Spena, Claudia Collà Ruvolo, Francesco Paolo Calace, Celeste Manfredi, Roberto La Rocca, Giuseppe Celentano, Carmine Turco, Marco Capece, Carlo D’Alterio, Alessandro Giordano, Ernesto di Mauro, Francesco Trama, Ugo Amicuzi, Davide Arcaniolo, Ferdinando Fusco, Nicola Longo, Di Bello, F, Creta, M, Napolitano, L, Califano, G, Passaro, F, Morra, S, Giovanni, Ad, Fusco, Gm, Cirillo, L, Abate, M, Morgera, V, Cacace, G, De Luca, L, Spena, G, Collà Ruvolo, C, Calace, Fp, Manfredi, C, La Rocca, R, Celentano, G, Turco, C, Capece, M, D'Alterio, C, Giordano, A, Mauro, Ed, Trama, F, Amicuzi, U, Arcaniolo, D, Fusco, F, Longo, N, Di Bello, Francesco, Creta, Massimiliano, Napolitano, Luigi, Califano, Gianluigi, Passaro, Francesco, Morra, Simone, Giovanni, Angelo di, Fusco, Giovanni Maria, Cirillo, Luigi, Abate, Marco, Morgera, Vincenzo, Cacace, Gianluigi, De Luca, Luigi, Spena, Gianluca, Collà Ruvolo, Claudia, Calace, Francesco Paolo, Manfredi, Celeste, La Rocca, Roberto, Celentano, Giuseppe, Turco, Carmine, Capece, Marco, D’Alterio, Carlo, Giordano, Alessandro, Mauro, Ernesto di, Trama, Francesco, Amicuzi, Ugo, Arcaniolo, Davide, Fusco, Ferdinando, and Longo, Nicola
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andrology, spinal cord injury, male infertility, sexual dysfunction, erectile dysfunction, pathophysiology, personalized treatment ,Medicine (miscellaneous) - Abstract
Spinal cord injury (SCI) is a relevant medical and social problem. According to the World Health Organization, the commonly estimated worldwide annual incidence of SCI is 40 to 80 cases per million population. After the SCI experience, most men present with sexual dysfunction (erectile dysfunction (ED) and ejaculatory dysfunction), fertility problems (such as impaired spermatogenesis, abnormalities in sperm viability, motility, and morphology), and systemic disorders such as genitourinary infection and endocrine imbalances. The best options available for managing the ejaculatory disorders in patients suffering from SCI are penile vibratory stimulation (PVS) and electroejaculation (EEJ). Furthermore, the treatment of ED in SCI patients consists of medical therapies including phosphodiesterase 5 inhibitors (PDE5i), intracavernosal injections (ICI), vacuum erection devices (VEDs), and surgical as penile prosthesis (PP). This review provides a snapshot of the current evidence for the mechanisms of sexual dysfunction and infertility in SCI patients, discusses the best management strategies for these conditions, and offers our perspective on the direction of future research.
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- 2022
37. Cetuximab, irinotecan and fluorouracile in fiRst-line treatment of immunologically-selected advanced colorectal cancer patients: the CIFRA study protocol
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Francesco Izzo, Anna Maria Trotta, Vittorio Albino, Lucrezia Silvestro, Antonio Avallone, Raffaele Palaia, Gerardo Botti, Monica Capozzi, Paolo Chiodini, Rossana Casaretti, Carmine Picone, Stefania Scala, Nicola Normanno, Mario Tamburini, Andrea Belli, Crescenzo D'Alterio, Anna Maria Rachiglio, Massimiliano Di Marzo, Guglielmo Nasti, Paolo Delrio, Cristin Roma, Anna Nappi, Carmela Romano, Antonella Petrillo, Antonino Cassata, Gianfranco De Feo, Alessandro Ottaiano, Salvatore Tafuto, Maria Napolitano, Alfonso Amore, Alfonso De Stefano, Ugo Pace, Luigi Portella, Ottaiano, A., Scala, S., Normanno, N., Napolitano, M., Capozzi, M., Rachiglio, A. M., Roma, C., Trotta, A. M., D'Alterio, C., Portella, L., Romano, C., Cassata, A., Casaretti, R., Silvestro, L., Nappi, A., Tafuto, S., Avallone, A., De Stefano, A., Tamburini, M., Picone, C., Petrillo, A., Izzo, F., Palaia, R., Albino, V., Amore, A., Belli, A., Pace, U., Di Marzo, M., Chiodini, P., Botti, G., De Feo, G., Delrio, P., and Nasti, G.
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0301 basic medicine ,Oncology ,Cancer Research ,medicine.medical_specialty ,Bevacizumab ,Antibody-dependent cell-mediated cytotoxicity ,Colorectal cancer ,Phase II study ,Cetuximab ,medicine.disease_cause ,Irinotecan ,Fluorouracule ,lcsh:RC254-282 ,03 medical and health sciences ,Study Protocol ,0302 clinical medicine ,Internal medicine ,Antineoplastic Combined Chemotherapy Protocols ,FcγR ,Genetics ,Medicine ,Panitumumab ,Humans ,Epidermal growth factor receptor ,neoplasms ,Colorectal Cancer ,Polymorphism, Genetic ,biology ,business.industry ,Receptors, IgG ,medicine.disease ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,digestive system diseases ,030104 developmental biology ,Treatment Outcome ,030220 oncology & carcinogenesis ,biology.protein ,KRAS ,Fluorouracil ,business ,Colorectal Neoplasms ,medicine.drug - Abstract
Background Combination of chemotherapies (fluoropirimidines, oxaliplatin and irinotecan) with biologic drugs (bevacizumab, panitumumab, cetuximab) have improved clinical responses and survival of metastatic colorectal cancer (mCRC). However, patients’ selection thorough the identification of predictive factors still represent a challange. Cetuximab (Erbitux®), a chimeric monoclonal antibody binding to the Epidermal Growth Factor Receptor (EGFR), belongs to the Immunoglobulins (Ig) grade 1 subclass able to elicite both in vitro and in vivo the Antibody-Dependent Cell-mediated Cytotoxicity (ADCC). ADCC is the cytotoxic killing of antibody-coated target cells by immunologic effectors. The effector cells express a receptor for the Fc portion of these antibodies (FcγR); genetic polymorphisms of FcγR modify the binding affinity with the Fc of IgG1. Interestingly, the high-affinity FcγRIIIa V/V is associated with increased ADCC in vitro and in vivo. Thus, ADCC could partially account for cetuximab activity. Methods/design CIFRA is a single arm, open-label, phase II study assessing the activity of cetuximab in combination with irinotecan and fluorouracile in FcγRIIIa V/V patients with KRAS, NRAS, BRAF wild type mCRC. The study is designed with a two-stage Simon model based on a hypothetical higher response rate (+ 10%) of FcγRIIIa V/V patients as compared to previous trials (about 60%) assuming ADCC as one of the possible mechanisms of cetuximab action. The test power is 95%, the alpha value of the I-type error is 5%. With these assumptions the sample for passing the first stage is 14 patients with > 6 responses and the final sample is 34 patients with > 18 responses to draw positive conclusions. Secondary objectives include toxicity, responses’ duration, progression-free and overall survival. Furthermore, an associated translational study will assess the patients’ cetuximab-mediated ADCC and characterize the tumor microenvironment. Discussion The CIFRA study will determine whether ADCC contributes to cetuximab activity in mCRC patients selected on an innovative immunological screening. Data from the translational study will support results’ interpretation as well as provide new insights in host-tumor interactions and cetuximab activity. Trial registration The CIFRA trial (version 0.0, June 21, 2018) has been registered into the NIH-US National Library of Medicine, ClinicalTrials.gov database with the identifier number (NCT03874062).
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- 2019
38. Novel Peptide-Based PET Probe for Non-invasive Imaging of C-X-C Chemokine Receptor Type 4 (CXCR4) in Tumors
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Paolo Gaballo, Stefania Scala, Stefano Tomassi, Ettore Novellino, Caterina Ieranò, Sara Santagata, Secondo Lastoria, Crescenzo D'Alterio, Luigi Portella, Salvatore Di Maro, Deborah Sementa, Margret Schottelius, Daria Di Martino, Antonio Luciano, Antonio Barbieri, Luciana Marinelli, Michela Aurilio, Anna Maria Trotta, Trotta, A. M., Aurilio, M., D'Alterio, C., Ierano, C., Di Martino, D., Barbieri, A., Luciano, A., Gaballo, P., Santagata, S., Portella, L., Tomassi, S., Marinelli, L., Sementa, D., Novellino, E., Lastoria, S., Scala, S., Schottelius, M., and Di Maro, S.
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Biodistribution ,Receptors, CXCR4 ,Mice, Nude ,Context (language use) ,Peptide ,Gallium Radioisotopes ,Mice, SCID ,01 natural sciences ,03 medical and health sciences ,chemistry.chemical_compound ,Heterocyclic Compounds, 1-Ring ,Mice ,In vivo ,Neoplasms ,Drug Discovery ,medicine ,DOTA ,Animals ,Humans ,Tissue Distribution ,Receptor ,030304 developmental biology ,chemistry.chemical_classification ,0303 health sciences ,Gallium Radioisotope ,CXCR4 antagonist ,medicine.diagnostic_test ,Animal ,Chemistry ,0104 chemical sciences ,3. Good health ,010404 medicinal & biomolecular chemistry ,Positron emission tomography ,Positron-Emission Tomography ,Cancer research ,Neoplasm ,Molecular Medicine ,Female ,Peptides ,Human - Abstract
The recently reported CXCR4 antagonist 3 (Ac-Arg-Ala-[DCys-Arg-2Nal-His-Pen]-CO2H) was investigated as a molecular scaffold for a CXCR4-targeted positron emission tomography (PET) tracer. Toward this end, 3 was functionalized with 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) and 1,4,7-triazacyclononanetriacetic acid (NOTA). On the basis of convincing affinity data, both tracers, [68Ga]NOTA analogue ([68Ga]-5) and [68Ga]DOTA analogue ([68Ga]-4), were evaluated for PET imaging in "in vivo" models of CHO-hCXCR4 and Daudi lymphoma cells. PET imaging and biodistribution studies revealed higher CXCR4-specific tumor uptake and high tumor/background ratios for the [68Ga]NOTA analogue ([68Ga]-5) than for the [68Ga]DOTA analogue ([68Ga]-4) in both in vivo models. Moreover, [68Ga]-4 and [68Ga]-5 displayed rapid clearance and very low levels of accumulation in all nontarget tissues but the kidney. Although the high tumor/background ratios observed in the mouse xenograft model could partially derive from the hCXCR4 selectivity of [68Ga]-5, our results encourage its translation into a clinical context as a novel peptide-based tracer for imaging of CXCR4-overexpressing tumors.
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- 2021
39. Aspects of seismic soil-pile-structure interaction in soft clay by centrifuge testing
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Thejesh Kumar Garala, G Madabhushi, Luca de Sanctis, Raffaele Di Laora, Stuart K. Haigh, Cristiano D'Alterio, Maria Iovino, Emmanouil Rovithis, aa.vv., Iovino, M., Rovithis, E., Di Laora, R., D'Alterio, C., de Sanctis, L., Garala, T. K., Haigh, S., and Madabhushi, G. S.
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Centrifuge ,Coupled soil-structure system ,Kaolin clay ,Kinematic soil-pile interaction ,Soft clay ,Geotechnical engineering ,Pile ,Geology - Abstract
This paper presents experimental data from two series of centrifuge tests on pile foundations embedded in a kaolin clay under earthquake excitation. A single pile and two pile-group configurations were tested in the centrifuge at 50g. In the first test series (flight 1) the seismic response of the soil-pile system was monitored, allowing experimentally-driven insights on the kinematic interaction between soil and pile. In the second series of tests (flight 2), a superstructure mass was attached to each foundation model, allowing investigation of the seismic behaviour of the coupled soil-foundation-structure (SFS) system. Two earthquake excitations were analysed during each flight having similar frequency and amplitude characteristics. Results are presented in terms of soil response along a vertical array, pile-caps spectral acceleration and superstructure top-to-ground surface response ratio. Experimental data suggests that for soft soils such as those employed in this experimental campaign, piles may amplify the motion with respect to the one at ground surface, while the natural period of the SFS system may be largely increased compared to its fixed-base counterpart, indicating a strong effect of soil compliance.
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- 2021
40. In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies
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Caterina Ieranò, Dario Righelli, Crescenzo D'Alterio, Maria Napolitano, Luigi Portella, Giuseppina Rea, Federica Auletta, Sara Santagata, Anna Maria Trotta, Giuseppe Guardascione, Federica Liotti, Nella Prevete, Piera Maiolino, Antonio Luciano, Antonio Barbieri, Annabella Di Mauro, Cristin Roma, Riziero Esposito Abate, Fabiana Tatangelo, Roberto Pacelli, Nicola Normanno, Rosa Marina Melillo, Stefania Scala, Ierano, C., Righelli, D., D'Alterio, C., Napolitano, M., Portella, L., Rea, G., Auletta, F., Santagata, S., Trotta, A. M., Guardascione, G., Liotti, F., Prevete, N., Maiolino, P., Luciano, A., Barbieri, A., Di Mauro, A., Roma, C., Esposito Abate, R., Tatangelo, F., Pacelli, R., Normanno, N., Melillo, R. M., and Scala, S.
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Pharmacology ,Cancer Research ,gastrointestinal neoplasm ,Immunology ,Membrane Proteins ,programmed cell death 1 receptor ,digestive system diseases ,Neoplasm Proteins ,Mice ,Nivolumab ,Oncology ,Colonic Neoplasms ,Animals ,Humans ,Molecular Medicine ,Immunology and Allergy ,Melanoma ,Cell Proliferation - Abstract
BackgroundColorectal cancer (CRC) is one of the most prevalent and deadly tumors worldwide. The majority of CRC is resistant to anti-programmed cell death-1 (PD-1)-based cancer immunotherapy, with approximately 15% with high-microsatellite instability, high tumor mutation burden, and intratumoral lymphocytic infiltration. Programmed death-ligand 1 (PD-L1)/PD-1 signaling was described in solid tumor cells. In melanoma, liver, and thyroid cancer cells, intrinsic PD-1 signaling activates oncogenic functions, while in lung cancer cells, it has a tumor suppressor effect. Our work aimed to evaluate the effects of the anti-PD-1 nivolumab (NIVO) on CRC cells.MethodsIn vitro NIVO-treated human colon cancer cells (HT29, HCT116, and LoVo) were evaluated for cell growth, chemo/radiotherapeutic sensitivity, apoptosis, and spheroid growth. Total RNA-seq was assessed in 6–24 hours NIVO-treated human colon cancer cells HT29 and HCT116 as compared with NIVO-treated PES43 human melanoma cells. In vivo mice carrying HT29 xenograft were intraperitoneally treated with NIVO, OXA (oxaliplatin), and NIVO+OXA, and the tumors were characterized for growth, apoptosis, and pERK1/2/pP38. Forty-eight human primary colon cancers were evaluated for PD-1 expression through immunohistochemistry.ResultsIn PD-1+ human colon cancer cells, intrinsic PD-1 signaling significantly decreased proliferation and promoted apoptosis. On the contrary, NIVO promoted proliferation, reduced apoptosis, and protected PD-1+ cells from chemo/radiotherapy. Transcriptional profile of NIVO-treated HT29 and HCT116 human colon cancer cells revealed downregulation of BATF2, DRAM1, FXYD3, IFIT3, MT-TN, and TNFRSF11A, and upregulation of CLK1, DCAF13, DNAJC2, MTHFD1L, PRPF3, PSMD7, and SCFD1; the opposite regulation was described in NIVO-treated human melanoma PES43 cells. Differentially expressed genes (DEGs) were significantly enriched for interferon pathway, innate immune, cytokine-mediated signaling pathways. In vivo, NIVO promoted HT29 tumor growth, thus reducing OXA efficacy as revealed through significant Ki-67 increase, pERK1/2 and pP38 increase, and apoptotic cell reduction. Eleven out of 48 primary human colon cancer biopsies expressed PD-1 (22.9%). PD-1 expression is significantly associated with lower pT stage.ConclusionsIn PD-1+ human colon cancer cells, NIVO activates tumor survival pathways and could protect tumor cells from conventional therapies.
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- 2022
41. A novel CXCR4 antagonist counteracts paradoxical generation of cisplatin-induced pro-metastatic niches in lung cancer
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Ugo Pastorino, Nadia Zaffaroni, Orazio Fortunato, Chiara Camisaschi, Giuliana Pollaci, Francesca Giovinazzo, Valeria Cancila, Giulia Bertolini, Massimo Milione, Massimo Moro, Federica Facchinetti, Monica Tortoreto, Giovanni Centonze, Claudia Chiodoni, Stefania Scala, Gabriella Sozzi, Crescenzo D'Alterio, Alessandro De Toma, Giulia Taiè, Luca Roz, Claudio Tripodo, Giuseppe Lo Russo, Bertolini G., Cancila V., Milione M., Lo Russo G., Fortunato O., Zaffaroni N., Tortoreto M., Centonze G., Chiodoni C., Facchinetti F., Pollaci G., Taie G., Giovinazzo F., Moro M., Camisaschi C., De Toma A., D'Alterio C., Pastorino U., Tripodo C., Scala S., Sozzi G., and Roz L.
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Male ,Receptors, CXCR4 ,Stromal cell ,Lung Neoplasms ,Settore MED/08 - Anatomia Patologica ,Monocytes ,Metastasis ,Mice ,Carcinoma, Non-Small-Cell Lung ,Cell Line, Tumor ,Drug Discovery ,Genetics ,Medicine ,Settore MED/05 - Patologia Clinica ,Animals ,Humans ,Drug Interactions ,AC133 Antigen ,Neoplasm Metastasis ,Lung cancer ,Molecular Biology ,Pharmacology ,Cisplatin ,CXCR4 antagonist ,chemotherapy, combination therapy, inflammatory monocytes, lung cancer stem cells, metastasis, peptide anti-CXCR4, SDF-1/CXCR4 axis ,business.industry ,medicine.disease ,Primary tumor ,Xenograft Model Antitumor Assays ,Extravasation ,Chemokine CXCL12 ,medicine.anatomical_structure ,RAW 264.7 Cells ,A549 Cells ,Cancer research ,Neoplastic Stem Cells ,Molecular Medicine ,Bone marrow ,business ,Peptides ,medicine.drug - Abstract
Platinum-based chemotherapy remains widely used in advanced non-small cell lung cancer (NSCLC) despite experimental evidence of its potential to induce long-term detrimental effects, including the promotion of pro-metastatic microenvironments. In this study, we investigated the interconnected pathways underlying the promotion of cisplatin-induced metastases. In tumor-free mice, cisplatin treatment resulted in an expansion in the bone marrow of CCR2+CXCR4+Ly6Chigh inflammatory monocytes (IMs) and an increase in lung levels of stromal SDF-1, the CXCR4 ligand. In experimental lung metastasis assays, cisplatin-induced IMs promoted the extravasation of tumor cells and the expansion of CD133+CXCR4+ metastasis-initiating cells (MICs). Peptide R, a novel CXCR4 inhibitor designed as an SDF-1 mimetic peptide, prevented cisplatin-induced IM expansion, the recruitment of IMs into the lungs, and the promotion of metastasis. At the primary tumor site, cisplatin treatment reduced tumor size while simultaneously inducing tumor release of SDF-1, MIC expansion, and recruitment of pro-invasive CXCR4+ macrophages. Co-recruitment of MICs and CCR2+CXCR4+ IMs to distant SDF-1-enriched sites also promoted spontaneous metastases that were prevented by CXCR4 blockade. In clinical specimens from NSCLC patients SDF-1 levels were found to be higher in platinum-treated samples and related to a worse clinical outcome. Our findings reveal that activation of the CXCR4/SDF-1 axis specifically mediates the pro-metastatic effects of cisplatin and suggest CXCR4 blockade as a possible novel combination strategy to control metastatic disease.
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- 2020
42. Aflibercept or bevacizumab in combination with FOLFIRI as second-line treatment of mRAS metastatic colorectal cancer patients: the ARBITRATION study protocol
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Guglielmo Nasti, Francesco Perri, N. Zanaletti, Alfonso De Stefano, Luigi Portella, Paola Del Prete, Mariachiara Santorsola, Paolo Chiodini, Francesco Izzo, Antonio Avallone, Anna Maria Trotta, Gerardo Botti, Alessandro Ottaiano, Annabella Di Mauro, Carmen Notariello, Amalia Luce, Michele Caraglia, Fabiana Tatangelo, Angela Lombardi, Ottavia Clemente, Vincenza Granata, Carmine Picone, Stefania Scala, Massimiliano Di Marzo, Daniela Rega, Vittorio Albino, Antonella Petrillo, Paolo Delrio, Anna Nappi, Gianfranco De Feo, Crescenzo D'Alterio, Ugo Pace, Ottaiano, A., Scala, S., Santorsola, M., Trotta, A. M., D'Alterio, C., Portella, L., Clemente, O., Nappi, A., Zanaletti, N., De Stefano, A., Avallone, A., Granata, V., Notariello, C., Luce, A., Lombardi, A., Picone, C., Petrillo, A., Perri, F., Tatangelo, F., Di Mauro, A., Albino, V., Izzo, F., Rega, D., Pace, U., Di Marzo, M., Chiodini, P., De Feo, G., Del Prete, P., Botti, G., Delrio, P., Caraglia, M., and Nasti, G.
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0301 basic medicine ,Oncology ,medicine.medical_specialty ,Bevacizumab ,Colorectal cancer ,colorectal cancer ,bevacizumab ,lcsh:RC254-282 ,Study Protocol ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,irinotecan ,Selection (genetic algorithm) ,Aflibercept ,business.industry ,aflibercept ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,medicine.disease ,Irinotecan ,030104 developmental biology ,030220 oncology & carcinogenesis ,second-line treatment ,Arbitration ,FOLFIRI ,business ,MRAS ,RAS ,medicine.drug - Abstract
Background: The intensive study of predictive factors has strongly ameliorated the therapeutic flow-chart of metastatic colorectal cancer (mCRC) by allowing the selection of patients who benefit from specific therapies. For instance, in mRAS (mutated RAS) mCRC patients, anti-EGFR drugs (cetuximab and panitumumab) are not recommended; in this group of patients, the use of anti-angiogenic drugs (bevacizumab and aflibercept) is predominant. However, at progression to standard bevacizumab-based first-line chemotherapy, still to date, there are no studies to guide oncologists in the choice of the best second-line anti-angiogenic drug (bevacizumab beyond progression versus aflibercept). Methods: ARBITRATION is a prospective, observational study assessing efficacy differences between second-line fluorouracil/irinotecan (FOLFIRI)/bevacizumab versus FOLFIRI/aflibercept at progression to fluoropyrimidines, oxaliplatin and bevacizumab in mRAS mCRC patients. A test power of 80%, a median survival of 9 months from second-line treatment start and a hazard ratio of 0.67 between the two schedules were the basis for statistical design. The final sample will be 220 patients (110 per treatment). The significance will be verified with a two-tailed log-rank test with an alpha value of the I-type error of 5%. Time-to-outcome will be described by Kaplan–Meier curves and prognostic factors studied through multivariable analyses based on the Cox model. Secondary objectives include safety, responses’ duration and progression-free survival. A translational research will be conducted to measure several angiogenic proteins in patients’ serum before starting the therapy in order to evidence any angiogenic factor patterns related to outcome. Discussion: We present a large, prospective, observational study aiming to answer two scientific questions: (1) outcome differences between second-line treatments with FOLFIRI/bevacizumab beyond progression versus FOLFIRI/aflibercept in mRAS mCRC patients, (2) angiogenic factors’ patterns that could associate with efficacy and help oncologists to apply best the therapeutic anti-angiogenic strategies. Trial registration: The ARBITRATION trial (version 0.0, 13 April 2020) has been registered into the clinicaltrials.gov registry on 20 May 2020 with identifier NCT04397601.
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- 2021
43. High-Frequency Ultrasound-Guided Injection for the Generation of a Novel Orthotopic Mouse Model of Human Thyroid Carcinoma
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Luigi Auletta, Crescenzo D'Alterio, Gennaro Di Maro, Adelaide Greco, Peppino Mirabelli, Antonella Zannetti, Giuliana Salvatore, Marco Salvatore, Andrea Soricelli, Sandra Albanese, Francesca Maria Orlandella, Greco, Adelaide, Albanese, S, Auletta, L, Mirabelli, P, Zannetti, A, D'Alterio, C, Di Maro, G, Orlandella, Fm, Salvatore, G, Soricelli, A, and Salvatore, M.
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0301 basic medicine ,Pathology ,medicine.medical_specialty ,endocrine system ,X-ray microtomography ,endocrine system diseases ,Endocrinology, Diabetes and Metabolism ,Mice, Nude ,Malignancy ,High-frequency ultrasound ,thyroid carcinoma ,Thyroid carcinoma ,03 medical and health sciences ,Mice ,0302 clinical medicine ,Endocrinology ,Cell Line, Tumor ,Ultrasound ,Adenocarcinoma, Follicular ,Carcinoma ,medicine ,Endocrine system ,Animals ,Humans ,Thyroid Neoplasms ,Neoplasm Metastasis ,Proportional Hazards Models ,Ultrasonography ,Mice, Inbred BALB C ,business.industry ,Incidence ,Thyroid ,X-Ray Microtomography ,medicine.disease ,Survival Rate ,Disease Models, Animal ,030104 developmental biology ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Adenocarcinoma ,Female ,business ,Neoplasm Transplantation - Abstract
Background: Thyroid carcinoma is the most common endocrine malignancy and has an increasing incidence. High-frequency ultrasound (HFUS) has a spatial resolution of 30 lm, which is a property that has been exploited for thyroid visualization and analysis in mice. The aim of this study was to generate a novel orthotopic mouse model of human follicular thyroid carcinoma (FTC) using an HFUS-guided injection system. Methods: Twenty Balb/C nude mice were injected in the right lobe of the thyroid with 2 · 106 FTC-133 cells using the microinjection HFUS-guided system, and 20 mice, used as a control, underwent surgical orthotopic implantation of 2 · 106 FTC-133 cells in the right lobe of the thyroid. All mice underwent HFUS imaging two weeks after cell injection; HFUS examinations and tumor volume (TV) measurements were repeated weekly. Micro– computed tomography was performed at different time points to determine whether lung metastasis had occurred. TVs were compared between the two models (surgical vs. HFUS-guided) using the Mann–WhitneyU-test, and the Mantel–Cox log-rank test was applied to evaluate the death hazard. Hematoxylin and eosin analysis of formalinfixed, paraffin-embedded mouse tissue was performed to validate the in vivo imaging results. Results: Of the HFUS-guided injected mice, 9/18 survived up to 40 days after the injection of tumor cells. Mice injected surgically had 100% mortality at day 29. Of 38 mice, 29 (14/18 HFUS, 15/20 surgical) showed metastasis in the salivary glands and lymph nodes, and 13 (10/18 HFUS, 3/20 surgical) also showed metastasis in the lungs, which was confirmed by histological analysis. In the surgical group, there was an evident, frequent (12/20 mice) involvement of the contralateral lobe of the thyroid, whereas this feature was only detected in 1/18 mice in the HFUS group. Statistical analysis showed the same pattern of growth in the two groups, and a significant hazard in the mice in the surgical group ( p = 0.03). Conclusions: This study demonstrated the technical feasibility of an HFUS-guided orthotopic mouse model of FTC. The HFUS-guided orthotopic model is easily reproducible and allows prolonged monitoring of the disease because the animals showed an increased survival rate.
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- 2016
44. High CXCR4 Expression Correlates with Sunitinib Poor Response in Metastatic Renal Cancer
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Giacomo Cartenì, A. La Mura, S. Perdonà, Luigi Portella, Crescenzo D'Alterio, Sandro Pignata, Gaetano Facchini, Oscar Nappi, G. Di Lorenzo, Stefania Scala, Riccardo Autorino, Renato Franco, Giuseppe Castello, Alessandro Ottaiano, Mino Rizzo, D' Alterio, C, Portella, L, Ottaiano, A, Rizzo, M, Carteni, G, Pignata, S, Facchini, G, Perdona, S, Di Lorenzo, G, Autorino, Riccardo, Franco, Renato, La Mura, A, Nappi, O, Castello, G, and Scala, S.
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Male ,Oncology ,Cancer Research ,Pathology ,Indoles ,Time Factors ,Angiogenesis Inhibitors ,Kaplan-Meier Estimate ,urologic and male genital diseases ,CXCR4 ,Risk Factors ,Drug Discovery ,Sunitinib ,Aged, 80 and over ,Middle Aged ,Immunohistochemistry ,Kidney Neoplasms ,Treatment Outcome ,Italy ,Predictive value of tests ,Female ,medicine.drug ,Adult ,Receptors, CXCR4 ,medicine.medical_specialty ,Risk Assessment ,Disease-Free Survival ,Predictive Value of Tests ,Cell Line, Tumor ,Internal medicine ,Biomarkers, Tumor ,medicine ,Carcinoma ,Humans ,Pyrroles ,RNA, Messenger ,Carcinoma, Renal Cell ,Grading (tumors) ,Aged ,Proportional Hazards Models ,Pharmacology ,Chi-Square Distribution ,Proportional hazards model ,business.industry ,medicine.disease ,Concomitant ,Multivariate Analysis ,Neoplasm Grading ,business - Abstract
Background: Almost 30% of the sunitinib-treated patients for metastatic renal carcinoma (mRCC) do not receive a clinical benefit. Convincing evidences demonstrated a cross talk between the VEGF and CXCR4 pathways. It was hypothesized that CXCR4 expression in primary renal cancer could predict sunitinib responsiveness. Patients and Methods: In this exploratory study sixty-two mRCC patients receiving sunitinib as first-line treatment were evaluated for CXCR4 expression through immunohistochemistry (IHC). Correlations between CXCR4 expression, baseline patients and tumour characteristics were studied by contingency tables and the chi-square test. Univariable analysis was performed with the log-rank test, and the Cox model was applied for multivariable analysis. Results: The objective response rate of sunitinib first-line therapy was 35.5% (22/62) with a disease control rate (response and stable disease) of 62.9% (39/62). CXCR4 expression was absent/low in 30 (48.4%), moderate in 17 (27.4%), and high in 15 (24.2%) tumors respectively. Low or absent CXCR4 expression predicted response to sunitinib therapy. Moreover, Fuhrman grading and concomitant, CXCR4 and Fuhrman grading, strongly predicted sunitinib first line therapy responsiveness on progression-free survival and overall survival. Conclusions: High CXCR4 expression correlates with sunitinib poor response in metastatic renal cancer
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- 2012
45. Identification of a distinct population of CD133+CXCR4+ cancer stem cells in ovarian cancer
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Stefano Greggi, Rosalba Camerlingo, Claudia Consales, Stefania Scala, Anna Maria Riccio, Virginia Tirino, Crescenzo D'Alterio, Caterina Ieranò, Nunzia Simona Losito, Sabrina Chiara Cecere, Michele Cioffi, Giuseppe Pirozzi, Sandro Pignata, Cioffi, M, D'Alterio, C, Camerlingo, R, Tirino, Virginia, Consales, C, Riccio, A, Ieranò, C, Cecere, Sc, Losito, N, Greggi, S, Pignata, S, Pirozzi, G, and Scala, S.
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Homeobox protein NANOG ,Receptors, CXCR4 ,Pathology ,medicine.medical_specialty ,endocrine system diseases ,Cellular differentiation ,Biology ,Article ,Kruppel-Like Factor 4 ,Mice ,SOX2 ,Antigens, CD ,Cancer stem cell ,medicine ,Animals ,Humans ,Cell Lineage ,AC133 Antigen ,neoplasms ,Glycoproteins ,Ovarian Neoplasms ,Multidisciplinary ,HCT116 Cells ,medicine.disease ,female genital diseases and pregnancy complications ,Drug Resistance, Neoplasm ,Amniotic epithelial cells ,embryonic structures ,Neoplastic Stem Cells ,Cancer research ,Female ,biological phenomena, cell phenomena, and immunity ,Cisplatin ,Stem cell ,Peptides ,Ovarian cancer ,Adult stem cell - Abstract
CD133 and CXCR4 were evaluated in the NCI-60 cell lines to identify cancer stem cell rich populations. Screening revealed that, ovarian OVCAR-3, -4 and -5 and colon cancer HT-29, HCT-116 and SW620 over expressed both proteins. We aimed to isolate cells with stem cell features sorting the cells expressing CXCR4+CD133+ within ovarian cancer cell lines. The sorted population CD133+CXCR4+ demonstrated the highest efficiency in sphere formation in OVCAR-3, OVCAR-4 and OVCAR-5 cells. Moreover OCT4, SOX2, KLF4 and NANOG were highly expressed in CD133+CXCR4+ sorted OVCAR-5 cells. Most strikingly CXCR4+CD133+ sorted OVCAR-5 and -4 cells formed the highest number of tumors when inoculated in nude mice compared to CD133−CXCR4−, CD133+CXCR4−, CD133−CXCR4+ cells. CXCR4+CD133+ OVCAR-5 cells were resistant to cisplatin, overexpressed the ABCG2 surface drug transporter and migrated toward the CXCR4 ligand, CXCL12. Moreover, when human ovarian cancer cells were isolated from 37 primary ovarian cancer, an extremely variable level of CXCR4 and CD133 expression was detected. Thus, in human ovarian cancer cells CXCR4 and CD133 expression identified a discrete population with stem cell properties that regulated tumor development and chemo resistance. This cell population represents a potential therapeutic target.
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- 2015
46. Protein gene product 9.5 is diagnostically helpful in delineating high-grade renal cell cancer involving the renal medullary/sinus region from invasive urothelial cell carcinoma of the renal pelvis
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Sabine Brookman-May, Wolfgang Otto, Stefan Koch, Crescenzo D'Alterio, Sven Gunia, Stefania Staibano, Andreas Erbersdobler, Gunia, S, Erbersdobler, A, Koch, S, Otto, W, Staibano, Stefania, D'Alterio, C, and Brookman May, S.
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Pathology ,medicine.medical_specialty ,Urothelial Cell ,PAX2 ,Vimentin ,urologic and male genital diseases ,Pathology and Forensic Medicine ,Carcinoma ,Biomarkers, Tumor ,Medicine ,Humans ,Kidney Pelvis ,Carcinoma, Renal Cell ,Retrospective Studies ,Kidney Medulla ,biology ,Papillary renal cell carcinomas ,business.industry ,CD117 ,medicine.disease ,Kidney Neoplasms ,medicine.anatomical_structure ,biology.protein ,Urothelium ,business ,PAX8 ,Renal pelvis ,Ubiquitin Thiolesterase - Abstract
The classification of poorly differentiated carcinomas involving the renal medullary/sinus region might be challenging on conventional histomorphologic grounds alone. However, delineation of high-grade renal cell carcinomas such as collecting duct (Bellini) carcinoma from urothelial cell carcinoma of the renal pelvis is critical, as it conveys important therapeutic implications. We assessed the so far neglected differential diagnostic role of protein gene product 9.5, a neuropeptide involved in intracellular proteolysis, in terms of differentiating invasive urothelial cell carcinomas of the renal pelvis from high-grade renal cell carcinomas infiltrating the renal medullary/sinus region. To this aim, 21 invasive urothelial cell carcinomas of the renal pelvis and 27 high-grade renal cell carcinomas (8 renal cell carcinomas with sarcomatoid dedifferentiation and 5 type 1 and 7 type 2 papillary renal cell carcinomas as well as 7 collecting duct carcinomas) were stained with antibodies directed against protein gene product 9.5, CD10, vimentin, CEA, p63, CK5/6, CK7, CK20, PAX2, PAX8, CD117 (c-Kit), AE1/3, α-methyl CoA racemase, actin, and desmin. Briefly, strong protein gene product 9.5 expression was observed in 6 (86%) of 7 collecting duct carcinomas, 8 (67%) of 12 papillary renal cell carcinomas, and 2 (25%) of 8 renal cell carcinomas with sarcomatoid dedifferentiation. Conversely, none of the 21 urothelial cell carcinomas investigated showed protein gene product 9.5 expression. Our findings suggest that protein gene product 9.5, particularly if used in conjunction with p63 and CK5/6, might be helpful in differentiating high-grade renal cell carcinomas from urothelial cell carcinomas of the renal pelvis, whereas its specificity with respect to the histologic subtyping of renal cell carcinomas seems to be low. However, because of the limited number of study cases enrolled in our investigation, our findings need to be validated in the future.
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- 2012
47. Inhibition of stromal CXCR4 impairs development of lung metastases
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Giosuè Scognamiglio, Crescenzo D'Alterio, Anna Maria Riccio, Antonio Barbieri, Caterina Ieranò, Domenica Rea, Renato Franco, Stefania Scala, Luigi Portella, Claudio Arra, Marianeve Polimeno, Giuseppe Palma, Jane Bryce, Antonio Luciano, D'Alterio, C, Barbieri, A, Portella, L, Palma, G, Polimeno, M, Riccio, A, Ierano, C, Franco, Renato, Scognamiglio, G, Bryce, J, Luciano, A, Rea, D, Arra, C, and Scala, S.
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Benzylamines ,Receptors, CXCR4 ,Pathology ,medicine.medical_specialty ,Cancer Research ,Lung Neoplasms ,Stromal cell ,Myeloid ,Immunology ,Melanoma, Experimental ,Antineoplastic Agents ,Cyclams ,CXCR4 ,Metastasis ,Mice ,Antigen ,Heterocyclic Compounds ,medicine ,Animals ,Antigens, Ly ,Immunology and Allergy ,Lymphocyte homing receptor ,Melanoma ,Chemistry ,Plerixafor ,medicine.disease ,Mice, Inbred C57BL ,medicine.anatomical_structure ,Oncology ,Pulmonary metastases ,Cancer research ,Original Article ,Female ,Stromal Cells ,Heterozygote mice ,Granulocytes ,medicine.drug - Abstract
Compelling evidence has emerged in recent years indicating that stromal cells play a critical role in disease progression. CXCR4 is a G-protein-coupled receptor with a major role in lymphocyte homing. Its ligand, CXCL12, is a highly efficient chemotactic factor for T cells, monocytes, pre-B cells, dendritic cells and myeloid bone marrow-derived cells (BMDCs). In addition, the CXCR4-CXCL12 axis plays a central role in tumor growth and metastasis. To evaluate the effect of genetic CXCR4 reduction on metastasis development, murine melanoma B16 cells were injected into the tail vein of C57BL/6 CXCR4(+/+) and CXCR4(+/-) mice in the presence of the CXCR4 inhibitor, Plerixafor (previously named AMD3100). Although lung metastases developed in wild-type CXCR4(+/+) and heterozygote CXCR4(+/-) mice, nodules were significantly smaller in the latter. CXCR4 pharmacological inhibition by Plerixafor further reduced lung metastases in CXCR4(+/-) mice, preserving the pulmonary architecture (4.18 ± 1.38 mm(2) vs. 1.11 ± 0.60 mm(2), p = 0.038). A reduction in LY6G-positive myeloid/granulocytic cells and in p38 MAPK activation was detected in lungs from CXCR4(+/-) mice compared to CXCR4(+/+) mice [LY6G-positive myeloid CXCR4(+/-) vs. CXCR4(+/+) (p = 0.0004); CXCR4(+/+) vs. CXCR4(+/+) Plerixafor-treated (p = 0.0031)] suggesting that CXCR4 reduction on myeloid-derived cells reduced their recruitment to the lung, consequently impairing lung metastases. Our findings argue in favor of a specific role of CXCR4 expressed in stromal cells that condition the pro-tumor microenvironment. In this scenario, CXCR4 antagonists will target neoplastic cells as well as the pro-tumor stromal microenvironment.
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48. Concomitant CXCR4 and CXCR7 expression predicts poor prognosis in renal cancer
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Luca Cindolo, Sisto Perdonà, Luigi Pucci, Renato Franco, Gaetano Facchini, Sandro Pignata, Stefania Scala, Luigi Marra, Alessandro Ottaiano, Susan Costantini, Giuseppe Castello, Michele Cioffi, Claudia Consales, L. Claudio, Giacomo Cartenì, Rosa Calemma, Marianeve Polimeno, Nicola Longo, Luigi Portella, Crescenzo D'Alterio, D'Alterio, C, Consales, C, Polimeno, M, Franco, Renato, Cindolo, L, Portella, L, Cioffi, M, Calemma, R, Marra, L, Claudio, L, Perdona, S, Pignata, S, Facchini, G, Carteni, G, Longo, N, Pucci, L, Ottaiano, A, Costantini, S, Castello, G, and Scala, S.
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Male ,Aging ,Receptors, CXCR4 ,Cancer Research ,Pathology ,medicine.medical_specialty ,Biology ,Kidney ,CXCR4 ,Disease-Free Survival ,Chemokine receptor ,Renal cell carcinoma ,Drug Discovery ,medicine ,Carcinoma ,Humans ,RNA, Messenger ,Carcinoma, Renal Cell ,Survival analysis ,Aged ,Neoplasm Staging ,Receptors, CXCR ,Pharmacology ,Reverse Transcriptase Polymerase Chain Reaction ,Cancer ,Kidney metabolism ,Prognosis ,medicine.disease ,Immunohistochemistry ,Survival Analysis ,Kidney Neoplasms ,Oncology ,Lymphatic Metastasis ,Concomitant ,Cancer research ,Female ,Neoplasm Recurrence, Local - Abstract
CXCR4 is a chemokine receptor implicated in the metastatic process. The CXCR4 ligand, CXCL12, was shown to bind also the CXCR7 receptor, a recently deorphanized chemokine receptor whose signalling pathway and function are still controversial. This study was conducted to determine patients clinic-pathological factors and outcome according to the expressions of CXCR4 and CXCR7 in renal cell carcinoma (RCC). CXCR4 and CXCR7 expression was evaluated in 223 RCC patients through immunohistochemistry; moreover CXCR4 and CXCR7 was detected in 49 others consecutive RCC patients trough RT- PCR. CXCR4 expression was low in 42/223 RCC (18.8%), intermediate in 71/223 (31.9%) and high in 110/223 (49.3%). CXCR7 expression was low in 44/223 RCC patients (19.8%), intermediate in 65/223 (29.1%) and high in 114/223 (51.1%). High CXCR4 and high CXCR7 expression predicted shorter disease free survival. In multivariate analysis, high CXCR4 expression (p= 0.0061), high CXCR7 (p= 0.0194) expression and the concomitant high expression of CXCR4 and CXCR7 (p= 0.0235) are independent prognosis factors. Through RT-PCR, CXCR4 was overexpressed in 36/49 and CXCR7 in 33/49 samples correlating with symptoms at diagnosis and lymph nodes status. So we can hypothesize that CXCR4 and CXCR7, singularly evaluated and in combination, are valuable prognostic factors in RCC patients.
49. Differential role of CD133 and CXCR4 in renal cell carcinoma
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Crescenzo D'Alterio, Luca Cindolo, Claudia Consales, Giacomo Cartenì, L. Claudio, Anna Maria Riccio, Massimo Mascolo, Luigi Marra, Michele Cioffi, Vincenzo Mirone, Luigi Portella, Vincenzo Ficarra, Guido Martignoni, Paolo Chiodini, Stefania Staibano, Nicola Longo, Sisto Perdonà, Renato Franco, Mario Falsaperla, Stefania Scala, Giuseppe Castello, Marianeve Polimeno, M. Puglisi, D'Alterio, C, Cindolo, L, Portella, L, Polimeno, M, Consales, C, Riccio, A, Cioffi, M, Franco, Renato, Chiodini, Paolo, Cartenì, G, Mirone, V, Longo, N, Marra, L, Perdonà, S, Claudio, L, Mascolo, M, Staibano, S, Falsaperla, M, Puglisi, M, Martignoni, G, Ficarra, V, Castello, G, Scala, S., Franco, R, Chiodini, P, Mirone, Vincenzo, Longo, Nicola, and Staibano, Stefania
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Adult ,Male ,Oncology ,Receptors, CXCR4 ,medicine.medical_specialty ,renal cell carcinoma ,Kaplan-Meier Estimate ,Biology ,Stem cell marker ,CXCR4 ,Disease-Free Survival ,Antigens, CD ,Renal cell carcinoma ,Cancer stem cell ,Cell Line, Tumor ,Internal medicine ,medicine ,Carcinoma ,Humans ,CD133 ,AC133 Antigen ,Carcinoma, Renal Cell ,neoplasms ,Molecular Biology ,Aged ,Glycoproteins ,Aged, 80 and over ,Univariate analysis ,Prognosis ,Age Factors ,Cancer ,Cell Biology ,Middle Aged ,medicine.disease ,Immunohistochemistry ,Kidney Neoplasms ,embryonic structures ,Cancer cell ,Cancer research ,Female ,Peptides ,Developmental Biology - Abstract
The chemokine receptor CXCR4 and CD133, putative stem cell markers, were previously described in renal cancer (RCC). To evaluate the biological and prognostic role of CD133 and CXCR4 in RCC the expression was evaluated through qPCR and immunoblotting in human renal cancer cell lines (786-O, A498, ACHN, CAKI-1, SN12C, TK10, UO31) and patients biopsies. Renal cancer cells and surgical biopsies expressed functional CXCR4 while CD133 was not detectable. CXCR4 and CD133 expression was then evaluated in 240 renal cancer patients through immunohistochemistry. CXCR4 and CD133 were low in 19.1% and 59.6%; intermediate in 20% and 17.9%; high in 60.8% and 22.5% of the cases, respectively. CXCR4 was overexpressed in tumours (p= 0.02), while CD133 was over expressed in healthy tissues (p= 0.04). Disease free survival Kaplan Meier plots suggest that prognosis is unfavourable for patients whose primary tumours express CXCR4 (p= 0.0199) but nor CD133 (p= 0.151) neither the concomitant CXCR4-CD133 (p=0.848) high expression affected prognosis. Analysis of prognostic factors suggests that age, clinical presentation, AJCC stage and CXCR4 had a significant prognostic value at the univariate analysis. The CXCR4 predictive ability was confirmed at the multivariate analysis while no prognostic role was identified for CD133.Thus concomitant CD133 and CXCR4 evaluation is not worth in RCC patient while the CXCR4 prognostic role encourage CXCR4 antagonists as promising therapeutic option.
50. A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration
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Giuseppe Castello, Renato Franco, Giuseppe Palmieri, P. Giuliano, Claudio Arra, Crescenzo D'Alterio, Maria Napolitano, Antonio Barbieri, Luigi Portella, Giuseppina Liguori, Michele Cioffi, Stefania Scala, Roberto Pacelli, Caterina Ieranò, Valentina Mettivier, Carla Rozzo, Ierano, C, Giuliano, P, D'Alterio, C, Cioffi, M, Mettivier, V, Portella, L, Napolitano, M, Barbieri, A, Arra, C, Liguori, G, Franco, Renato, Palmieri, G, Rozzo, C, Pacelli, R, Castello, G, Scala, S., Franco, R, and Pacelli, Roberto
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Receptors, CXCR4 ,Chemokine receptor CCR5 ,Molecular Sequence Data ,Glycine ,C-C chemokine receptor type 7 ,C-C chemokine receptor type 6 ,CCR8 ,AMD3100 ,Mice ,Cell Movement ,Cell Line, Tumor ,Neoplasms ,Animals ,Humans ,Point Mutation ,Amino Acid Sequence ,CXCL14 ,Molecular Biology ,CXCL16 ,Cell Proliferation ,CXCR4 ,Alanine ,biology ,chemokine receptor ,Cell Biology ,CXCL12 ,Molecular biology ,Chemokine CXCL12 ,Amino Acid Substitution ,Epidermoid carcinoma ,Cancer research ,biology.protein ,Mutant Proteins ,A431 cells ,CXC chemokine receptor ,Developmental Biology - Abstract
The chemokine receptor CXCR4 is widely expressed in human cancers and regulates cell invasion, proliferation and survival. Because mutations in the CXCR4 gene could regulate its function we sequenced the coding region of the CXCR4 gene in 18 human melanoma and 3 human colon carcinoma cell lines. The same somatic point mutation (G574A; V160I) in the fourth transmembrane region of CXCR4 was detected in one colon cancer cell line (PD) and one melanoma cell line (LB). CXCR4 was expressed and functional in both PD and LB cells, PD and LB cells migrated specifically toward the receptor ligand, CXCL12 and P-Erk was specifically induced by CXCL12. To give insight into the function of the mutant CXCR4 receptor, human A431, epidermoid carcinoma cells, were stably transfected with both mutant and wild type CXCR4. In vitro, A431 cells harboring CXCR4(G574A) migrated specifically toward CXCL12 and CXCL12 induced ERK phosphorylation. Interestingly, in vivo studies showed that the growth of A431 tumors harboring CXCR4(G574A) was delayed compared to those harboring WT CXCR4. As expected, treatment with AMD3100, a specific CXCR4 inhibitor, reduced the in vivo growth of CXCR4(G574A) tumor b(G574A) but surprisingly, increased the growth of CXCR4(G574A) A431 cells. This is the first report of a spontaneously occurring, functionally active CXCR4 mutation in human cancer cells. While the mutation impairs cell growth in vivo, the CXCR4 inhibitor, AMD3100, stimulated the growth of cells harboring CXCR4(G574A).
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