2,124 results on '"D'Agostino, M. A."'
Search Results
2. Robotic approach for the treatment of gynecological cancers recurrences: A ten-year single-institution experience
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Certelli, Camilla, Palmieri, Luca, Federico, Alex, Oliva, Riccardo, Conte, Carmine, Rosati, Andrea, Vargiu, Virginia, Tortorella, Lucia, Chiantera, Vito, Foschi, Nazario, Ardito, Francesco, Lodoli, Claudio, Bruno, Matteo, Santullo, Francesco, De Rose, Agostino M., Fagotti, Anna, Fanfani, Francesco, Scambia, Giovanni, and Gallotta, Valerio
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- 2024
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3. Feasibility and operative outcomes of surgery in the liver area in advanced ovarian cancer
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Rosati, Andrea, De Rose, Agostino M., Gallotta, Valerio, Giannarelli, Diana, Ghirardi, Valentina, Pavone, Matteo, De Palma, Antonella, Conte, Carmine, Marchetti, Claudia, Gallucci, Valeria, Ardito, Francesco, Giuliante, Felice, Querleu, Denis, Scambia, Giovanni, and Fagotti, Anna
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- 2024
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4. The Double Chooz antineutrino detectors
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Double Chooz Collaboration, de Kerret, H., Abe, Y., Aberle, C., Abrahão, T., Ahijado, J. M., Akiri, T., Alarcón, J. M., Alba, J., Almazan, H., Anjos, J. C. dos, Appel, S., Ardellier, F., Barabanov, I., Barriere, J. C., Baussan, E., Baxter, A., Bekman, I., Bergevin, M., Bernstein, A., Bertoli, W., Bezerra, T. J. C., Bezrukov, L., Blanco, C., Bleurvacq, N., Blucher, E., Bonet, H., Bongrand, M., Bowden, N. S, Brugière, T., Buck, C., Avanzini, M. Buizza, Busenitz, J., Cabrera, A., Calvo, E., Camilleri, L., Carr, R., Cazaux, S., Cela, J. M., Cerrada, M., Chang, P. J., Charon, P., Chauveau, E., Chimenti, P., Classen, T., Collin, A. P., Conover, E., Conrad, J. M, Cormon, S., Corpace, O., Courty, B., Crespo-Anadón, J. I., Cribier, M., Crum, K., Cuadrado, S., Cucoanes, A., D'Agostino, M., Damon, E., Dawson, J. V., Dazeley, S., Dierckxsens, M., Dietrich, D., Djurcic, Z., Dorigo, F., Dracos, M., Durand, V., Efremekov, Y., Elnimr, M., Etenko, A., Falk, E., Fallot, M., Fechner, M., Felde, J., Fernandes, S. M., Fernández-Bedoya, C., Francia, D., Franco, D., Fischer, V., Franke, A. J., Franke, M., Furuta, H., Garcia, F., Garcia, J., Gil-Botella, I., Giot, L., Givaudan, A., Göger-Neff, M., Gomez, H., Gonzalez, L. F. G., Goodenough, L., Goodman, M. C., Goon, J., Gramlich, B., Greiner, D., Guertin, A., Guillon, B., Habib, S. M., Haddad, Y., Hara, T., Hartmann, F. X., Hartnell, J., Haser, J., Hatzikoutelis, A., Hellwig, D., Hervé, S., Hofacker, R., Horton-Smith, G., Hourlier, A., Ishitsuka, M., Jänner, K., Jiménez, S., Jochum, J., Jollet, C., Kaether, F., Kale, K., Kalousis, L., Kamyshkov, Y., Kaneda, M., Kaplan, D. M., Karakac, M., Kawasaki, T., Kemp, E., Kibe, Y., Kirchner, T., Konno, T., Kryn, D., Kutter, T., Kuze, M., Lachenmaier, T., Lane, C. E., Langbrandtner, C., Lasserre, T., Lastoria, C., Latron, L., Leonardo, C., Letourneau, A., Lhuillier, D., Lima Jr, H. P., Lindner, M., López-Castaño, J. M., LoSecco, J. M., Lubsandorzhiev, B., Lucht, S., Maeda, J., Maesano, C. N., Mariani, C., Maricic, J., Marie, F., Martinez, J. J., Martino, J., Matsubara, T., McKee, D., Meigner, F., Mention, G., Meregaglia, A., Meyer, J. P., Miletic, T., Milincic, R., Millot, J. F., Minotti, A., Mirones, V., Miyata, H., Mueller, Th. A., Nagasaka, Y., Nakajima, K., Navas-Nicolás, D., Nikitenko, Y., Novella, P., Oberauer, L., Obolensky, M., Onillon, A., Oralbaev, A., Ostrovskiy, I., Palomares, C., Peeters, S. J. M., Pepe, I. M., Perasso, S., Perrin, P., Pfahler, P., Porta, A., Pronost, G., Puras, J. C., Quéval, R., Ramirez, J. L., Reichenbacher, J., Reinhold, B., Reissfelder, M., Remoto, A., Reyna, D., Rodriguez, I., Röhling, M., Roncin, R., Rudolf, N., Rybolt, B., Sakamoto, Y., Santorelli, R., Sato, F., Schwan, U., Scola, L., Settimo, M., Schönert, S., Schoppmann, S., Shaevitz, M. A., Sharankova, R., Sibille, V., Sida, J. L., Sinev, V., Shrestha, D., Skorokhvatov, M., Soldin, P., Spitz, J., Stahl, A., Stancu, I., Starzynski, P., Stock, M. R., Stokes, L. F. F., Strait, M., Stüken, A., Suekane, F., Sukhotin, S., Sumiyoshi, T., Sun, Y., Sun, Z., Svoboda, R., Tabata, H., Tamura, N., Terao, K., Tonazzo, A., Toral, F., Toups, M., Thi, H. Trinh, Valdivia, F., Valdiviesso, G., Vassilopoulos, N., Verdugo, A., Veyssiere, C., Viaud, B., Vignaud, D., Vivier, M., Wagner, S., Wiebusch, C., White, B., Winslow, L., Worcester, M., Wurm, M., Wurtz, J., Yang, G., Yáñez, J., Yermia, F., and Zbiri, K.
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Physics - Instrumentation and Detectors - Abstract
This article describes the setup and performance of the near and far detectors in the Double Chooz experiment. The electron antineutrinos of the Chooz nuclear power plant were measured in two identically designed detectors with different average baselines of about 400 m and 1050 m from the two reactor cores. Over many years of data taking the neutrino signals were extracted from interactions in the detectors with the goal of measuring a fundamental parameter in the context of neutrino oscillation, the mixing angle {\theta}13. The central part of the Double Chooz detectors was a main detector comprising four cylindrical volumes filled with organic liquids. From the inside towards the outside there were volumes containing gadolinium-loaded scintillator, gadolinium-free scintillator, a buffer oil and, optically separated, another liquid scintillator acting as veto system. Above this main detector an additional outer veto system using plastic scintillator strips was installed. The technologies developed in Double Chooz were inspiration for several other antineutrino detectors in the field. The detector design allowed implementation of efficient background rejection techniques including use of pulse shape information provided by the data acquisition system. The Double Chooz detectors featured remarkable stability, in particular for the detected photons, as well as high radiopurity of the detector components., Comment: 49 pages, 29 figures
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- 2022
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5. Bile duct injury after cholecystectomy: timing of surgical repair should be based on clinical presentation. The experience of a tertiary referral center with Hepp-Couinaud hepatico-jejunostomy
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Giuliante, Felice, Panettieri, Elena, De Rose, Agostino M., Murazio, Marino, Vellone, Maria, Mele, Caterina, Clemente, Gennaro, Giovannini, Ivo, Nuzzo, Gennaro, and Ardito, Francesco
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- 2023
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6. Benchmarks and Geographic Differences in Gallbladder Cancer Surgery: An International Multicenter Study
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Vega, Eduardo A., Newhook, Timothy E., Mellado, Sebastian, Ruzzenente, Andrea, Okuno, Masayuki, De Bellis, Mario, Panettieri, Elena, Ahmad, M. Usman, Merlo, Ignacio, Rojas, Jesus, De Rose, Agostino M., Nishino, Hiroto, Sinnamon, Andrew J., Donadon, Matteo, Hauger, Marit S., Guevara, Oscar A., Munoz, Cesar, Denbo, Jason W., Chun, Yun Shin, Tran Cao, Hop S., Sanchez Claria, Rodrigo, Tzeng, Ching-Wei D., De Aretxabala, Xabier, Vivanco, Marcelo, Brudvik, Kristoffer W., Seo, Satoru, Pekolj, Juan, Poultsides, George A., Torzilli, Guido, Giuliante, Felice, Anaya, Daniel A., Guglielmi, Alfredo, Vinuela, Eduardo, and Vauthey, Jean-Nicolas
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- 2023
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7. Toward Enhancing Security in Intelligent Transportation: A Simulation-Based Approach
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Ali, Wasim A., Mangini, Agostino M., Júlvez, Jorge, Mahulea, Cristian, and Fanti, Maria Pia
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- 2024
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8. OP0088 ENTHESEAL TISSUE SIGNATURE IN RESPONSE TO IL-17 BLOCKADE IN PSORIATIC ARTHRITIS - RESULTS FROM THE EBIO ENTHESIAL BIOPSY STUDY
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Raimondo, M. G., primary, Mohammadian, H., additional, Alivernini, S., additional, Fedorchenko, V., additional, Rauber, S., additional, Labinsky, H., additional, Angeli, M., additional, Fagni, F., additional, Corte, G., additional, Tascilar, K., additional, Bräuer, L., additional, D’Agostino, M. A., additional, Schett, G., additional, Kleyer, A., additional, Pachowsky, M., additional, and Ramming, A., additional
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- 2024
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9. AB1183 THE USE OF MYCOPHENOLATE MOFETIL IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS IS ASSOCIATED WITH A REDUCED RISK OF VASCULAR COMPLICATIONS REQUIRING PHARMACOLOGICAL INTERVENTION UPGRADES
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De Lorenzis, E., primary, Bosello, S. L., additional, Cacciapaglia, F., additional, De Angelis, R., additional, Cipolletta, E., additional, Natalello, G., additional, D’agostino, M. A., additional, Codullo, V., additional, De Luca, G., additional, Giuggioli, D., additional, Ingegnoli, F., additional, Riccieri, V., additional, Ferri, C., additional, and Matucci-Cerinic, M., additional
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- 2024
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10. POS1479-HPR TRAVEL DISTANCE TO TERTIARY HEALTHCARE REFLECTS DISEASE SEVERITY AND MEDICATION ACCESS IN SYSTEMIC SCLEROSIS PATIENTS: INSIGHTS FROM THE ITALIAN SPRING REGISTRY
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De Lorenzis, E., primary, Natalello, G., additional, Cacciapaglia, F., additional, De Angelis, R., additional, Cipolletta, E., additional, D’agostino, M. A., additional, Codullo, V., additional, De Luca, G., additional, Giuggioli, D., additional, Ingegnoli, F., additional, Riccieri, V., additional, Ferri, C., additional, Matucci-Cerinic, M., additional, and Bosello, S. L., additional
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- 2024
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11. OP0296 ARRHYTHMIC BURDEN, MYOCARDIAL MARKERS, AND LONG-TERM SURVIVAL IN DISTINCT CARDIAC MAGNETIC RESONANCE SUBSETS OF SYSTEMIC SCLEROSIS
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Cerasuolo, P. G., primary, De Lorenzis, E., additional, Natalello, G., additional, Alonzi, G., additional, Fiore, S., additional, DI Murro, S., additional, Zoli, A., additional, Boni, V., additional, Del Galdo, F., additional, Denton, C. P., additional, Gabrielli, F. A., additional, Marano, R., additional, D’agostino, M. A., additional, and Bosello, S. L., additional
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- 2024
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12. POS1142 DEVELOPMENT AND VALIDATION OF A RULE-BASED FRAMEWORK FOR AUTOMATED IDENTIFICATION OF LONGITUDINAL CLINICAL FEATURES ABOUT SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS FROM ELECTRONIC HEALTH RECORDS
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Ortolan, A., primary, Lilli, L., additional, Bosello, S. L., additional, Antenucci, L., additional, Masciocchi, C., additional, Lenkowicz, J., additional, Cerasuolo, P., additional, Lanzo, L., additional, Piunno, S., additional, Castellino, G., additional, Gorini, M., additional, Patarnello, S., additional, and D’ Agostino, M. A., additional
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- 2024
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13. AB1326 METHOTREXATE VERSUS TOCILIZUMAB IN MAINTAINING REMISSION: A RETROSPECTIVE MONOCENTRIC COHORT STUDY IN PATIENTS WITH GIANT CELL ARTERITIS
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Rubortone, P., primary, Lazzaro, F. G., additional, Leone, F., additional, Gigante, M. R., additional, Bosello, S. L., additional, Ortolan, A., additional, and D’ Agostino, M. A., additional
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- 2024
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14. OP0193 BITEING MULTI-DRUG RESISTANT RHEUMATOID ARTHRITIS WITH CD19-T CELL ENGAGERS
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Bucci, L., primary, Hagen, M., additional, Rothe, T., additional, Raimondo, M. G., additional, Fagni, F., additional, Tur, C., additional, Wirsching, A., additional, Wacker, J., additional, Wilhelm, A., additional, Auger, J. P., additional, Eckstein, M., additional, Alivernini, S., additional, Zoli, A., additional, Bozec, A., additional, D’agostino, M. A., additional, Schett, G., additional, and Grieshaber-Bouyer, R., additional
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- 2024
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15. POS0875 DEFINING THE THRESHOLD OF NORMALITY IN MUSCULOSKELETAL ULTRASOUND; AN OMERACT ULTRASOUND STUDY
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Sahbudin, I., primary, Trickey, J., additional, Gouze, H., additional, Stoenoiu, M. S., additional, Filippou, G., additional, Sakellariou, G., additional, Maruseac, M., additional, Wittoek, R., additional, Carron, P., additional, Tinazzi, I., additional, Iagnocco, A., additional, Serban, T., additional, Azzolin, I., additional, Terslev, L., additional, Ammitzbøll-Danielsen, M., additional, Nyhuus Bendix Rasch, M., additional, Hauge, E. M., additional, Hammer, H. B., additional, Milchert, M., additional, Fliciński, J., additional, Mandl, P., additional, Borst, C., additional, Fodor, D., additional, Vreju, F. A., additional, Karalilova, R., additional, Naredo, E., additional, Sifuentes-Cantú, C., additional, La Paglia, G. M. C., additional, Pineda, C., additional, Gutierrez, M., additional, Leon, G., additional, Reátegui-Sokolova, C., additional, Mortada, M. A., additional, Suzuki, T., additional, Ikeda, K., additional, Ciurtin, C., additional, Kortekaas, M., additional, Ohrndorf, S., additional, Keen, H., additional, Bruyn, G., additional, Filer, A., additional, and D’agostino, M. A., additional
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- 2024
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16. AB0542 ULTRASOUND VS CLINICAL REMISSION IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS: CONCORDANCE AND RELATIONSHIP WITH THERAPY DISCONTINUATION
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La Ferrara, R., primary, Lazzaro, F. G., additional, Alonzi, G., additional, Fiore, S., additional, Peluso, G., additional, Fedele, A. L., additional, D’ Agostino, M. A., additional, and Ortolan, A., additional
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- 2024
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17. POS1372 CONTRAST-ENHANCED ULTRASOUND AS A VALUABLE TOOL TO DETECT MINIMAL INFLAMMATION IN RA PATIENTS IN PERSISTENT REMISSION
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Polido-Pereira, J., primary, Silvério-António, M., additional, Khmelinskii, N., additional, Arese, M., additional, Teixeira, R. L., additional, Vieira-Sousa, E., additional, D’agostino, M. A., additional, and Fonseca, J. E., additional
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- 2024
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18. POS0913 EVALUATION OF THE IMPLEMENTATION OF THE EULAR RECOMMENDATION CHECK LIST FOR TRANSPARENT AND COMPREHENSIVE REPORTING OF ULTRASOUND STUDIES IN RHEUMATIC AND MUSCULOSKELETAL DISEASES
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Mandl, P., primary, De Lorenzis, E., additional, Lazzaro, F. G., additional, Wildner, B., additional, and D’agostino, M. A., additional
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- 2024
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19. POS0805 SUSTAINED IMPROVEMENTS WITH BIMEKIZUMAB IN PATIENT-REPORTED SYMPTOMS OF AXIAL SPONDYLOARTHRITIS: 2-YEAR RESULTS FROM TWO PHASE 3 STUDIES
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Marzo-Ortega, H., primary, Mease, P. J., additional, Dougados, M., additional, Dubreuil, M., additional, Magrey, M., additional, Rudwaleit, M., additional, D’agostino, M. A., additional, De la Loge, C., additional, Fleurinck, C., additional, Massow, U., additional, Taieb, V., additional, and Deodhar, A., additional
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- 2024
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20. POS0943 GUSELKUMAB PROVIDES DURABLE IMPROVEMENTS IN PAIN AMONG PATIENTS WITH PSORIATIC ARTHRITIS AND AN INADEQUATE RESPONSE TO TNFi: COSMOS PHASE 3b TRIAL
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Coates, L. C., primary, Schett, G., additional, D’agostino, M. A., additional, Ramírez, J., additional, Sharaf, M., additional, Rampakakis, E., additional, Koivunen, M., additional, Zimmermann, M., additional, Lavie, F., additional, and Helliwell, P. S., additional
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- 2024
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21. OP0062 MULTI-MODAL ANALYSIS OF SYNOVIAL TISSUE MACROPHAGES INFORMS ON TREATMENT RESPONSE IN NAIVE TO TREATMENT RHEUMATOID ARTHRITIS
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Alivernini, S., primary, Perniola, S., additional, Tolusso, B., additional, Elmesmari, A., additional, Gessi, M., additional, Mario, C. DI, additional, Coletto, L. A., additional, Gigante, M. R., additional, Petricca, L., additional, Pacucci, V. A., additional, Bruno, D., additional, Somma, D., additional, Macdonald, L., additional, Benvenuto, R., additional, Bui, L., additional, D’agostino, M. A., additional, Gremese, E., additional, Bacardit, J., additional, and Kurowska-Stolarska, M., additional
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- 2024
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22. AB1496 MICROCIRCULATION CHARACTERIZATION IN ANOREXIA NERVOSA PATIENTS WITH RAYNAUD’S PHENOMENON
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Natalello, G., primary, Zoli, A., additional, Cerasuolo, P. G., additional, Murro, S. DI, additional, Alonzi, G., additional, Fiore, S., additional, Boni, V., additional, De Lorenzis, E., additional, Policola, C., additional, Moccia, L., additional, Anesini, M. B., additional, Rinaldi, L., additional, Sani, G., additional, Pontecorvi, A., additional, D’agostino, M. A., additional, and Bosello, S. L., additional
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- 2024
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23. OP0265 RITUXIMAB RETENTION RATE IN SYSTEMIC SCLEROSIS: A REAL-LIFE ITALIAN MULTICENTER STUDY
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De Luca, G., primary, De Lorenzis, E., additional, Campochiaro, C., additional, Cacciapaglia, F., additional, Del Papa, N., additional, Zanatta, E., additional, Airo’, P., additional, Lazzaroni, M. G., additional, Giuggioli, D., additional, De Santis, M., additional, Alonzi, G., additional, Stano, S., additional, Binda, M., additional, Moccaldi, B., additional, Tonutti, A., additional, Cavalli, S., additional, Iannone, F., additional, D’ Agostino, M. A., additional, Dagna, L., additional, Matucci-Cerinic, M., additional, and Bosello, S. L., additional
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- 2024
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24. POS0915 HARMONISING CONSENSUS AND RELIABILITY STUDIES IN MUSCULOSKELETAL ULTRASOUND
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Mandl, P., primary, Carstensen, S. M. D., additional, Terslev, L., additional, Keen, H., additional, Pineda, C., additional, and D’agostino, M. A., additional
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- 2024
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25. AB1067 VALIDATION OF MACHINE LEARNING ALGORITHM TO CHARACTERIZE DISEASE COMPLEXITY AND FLARES IN SYSTEMIC LUPUS ERYTHEMATOSUS
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Bosello, S. L., primary, Lilli, L., additional, Masciocchi, C., additional, Antenucci, L., additional, Lenkowicz, J., additional, Ortolan, A., additional, Cerasuolo, P. G., additional, Lanzo, L., additional, Piunno, S., additional, Castellino, G., additional, Gorini, M., additional, Patarnello, S., additional, and D’agostino, M. A., additional
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- 2024
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26. POS1418 ESOPHAGEAL MUCOSAL EROSIONS CAN PREDICT THE DETERIORATION OF LUNG FUNCTION OVER A FOUR-YEAR FOLLOW-UP PERIOD AND LONG-TERM MORTALITY IN PATIENTS WITH INTERSTITIAL LUNG DISEASE ASSOCIATED WITH SCLERODERMA
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De Lorenzis, E., primary, Alonzi, G., additional, Natalello, G., additional, Berardini, L., additional, Verardi, L., additional, Cerasuolo, P. G., additional, Papa, A., additional, Richeldi, L., additional, D’agostino, M. A., additional, and Bosello, S. L., additional
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- 2024
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27. POS0568 PREVALENCE OF ULTRASOUND FINDINGS SUGGESTIVE OF INFLAMMATORY ARTHRITIS AND GOUT-SPECIFIC LESIONS IN PATIENTS WITH GOUT: THE ECHOGOUT STUDY
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Gouze, H., primary, Melpignano, F., additional, Ruel-Gagné, S., additional, Padovano, I., additional, Vidal, F., additional, Breban, M., additional, and D’agostino, M. A., additional
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- 2024
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28. POS0030 SAFETY AND PRELIMINARY EFFICACY OF CD19 CAR-T CELL TREATMENT IN RHEUMATIC DISEASE- DATA FROM THE FIRST PART OF THE PHASE I/II CASTLE BASKET STUDY
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Schett, G., primary, Bohr, D., additional, Mueller, F., additional, Hagen, M., additional, Bergmann, C., additional, Tur, C., additional, Völkl, S., additional, Aigner, M., additional, Krestchmann, S., additional, Spörl, S., additional, Vasova, I., additional, Aletaha, D., additional, Kiener, H., additional, Natalello, G., additional, Grieshaber-Bouyer, R., additional, Bozec, A., additional, Locatelli, F., additional, D`agostino, M. A., additional, and Mackensen, A., additional
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- 2024
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29. Experimental study of precisely selected evaporation chains in the decay of excited $^{25}$Mg
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Camaiani, A., Casini, G., Morelli, L., Barlini, S., Piantelli, S., Baiocco, G., Bini, M., Bruno, M., Buccola, A., Cinausero, M., Cicerchia, M., D'Agostino, M., Degelier, M., Fabris, D., Frosin, C., Gramegna, F., Gulminelli, F., Mantovani, G., Marchi, T., Olmi, A., Ottanelli, P., Pasquali, G., Pastore, G., Valdre, S., and Verde, G.
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Nuclear Experiment - Abstract
The reaction $^{12}$C + $^{13}$C at 95 MeV bombarding energy is studied using the GARFIELD + Ring Counter apparatus located at the INFN Laboratori Nazionali di Legnaro. In this paper we want to investigate the de-excitation of $^{25}$Mg aiming both at a new stringent test of the statistical description of nuclear decay and a direct comparison with the decay of the system $^{24}$Mg formed through $^{12}$C+$^{12}$C reactions previously studied. Thanks to the large acceptance of the detector and to its good fragment identification capabilities, we could apply stringent selections on fusion-evaporation events, requiring their completeness in charge. The main decay features of the evaporation residues and of the emitted light particles are overall well described by a pure statistical model; however, as for the case of the previously studied 24Mg, we observed some deviations in the branching ratios, in particular for those chains involving only the evaporation of $\alpha$ particles. From this point of view the behavior of the $^{24}$Mg and $^{25}$Mg decay cases appear to be rather similar. An attempt to obtain a full mass balance even without neutron detection is also discussed.
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- 2018
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30. Productivity changes in the automotive industry of three European countries. An application of the Malmquist index decomposition analysis
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Agostino, M., Nifo, A., Ruberto, S., Scalera, D., and Trivieri, F.
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- 2022
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31. The Double Chooz antineutrino detectors
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de Kerret, H., Abe, Y., Aberle, C., Abrahão, T., Ahijado, J. M., Akiri, T., Alarcón, J. M., Alba, J., Almazan, H., dos Anjos, J. C., Appel, S., Ardellier, F., Barabanov, I., Barriere, J. C., Baussan, E., Baxter, A., Bekman, I., Bergevin, M., Bernstein, A., Bertoli, W., Bezerra, T. J. C., Bezrukov, L., Blanco, C., Bleurvacq, N., Blucher, E., Bonet, H., Bongrand, M., Bowden, N. S, Brugière, T., Buck, C., Avanzini, M. Buizza, Busenitz, J., Cabrera, A., Caden, E., Calvo, E., Camilleri, L., Carr, R., Cazaux, S., Cela, J. M., Cerrada, M., Chang, P. J., Charon, P., Chauveau, E., Chimenti, P., Classen, T., Collin, A. P., Conover, E., Conrad, J. M, Cormon, S., Corpace, O., Courty, B., Crespo-Anadón, J. I., Cribier, M., Crum, K., Cuadrado, S., Cucoanes, A., D’Agostino, M., Damon, E., Dawson, J. V., Dazeley, S., Dierckxsens, M., Dietrich, D., Djurcic, Z., Dorigo, F., Dracos, M., Durand, V., Efremeko, Y., Elnimr, M., Etenko, A., Falk, E., Fallot, M., Fechner, M., Felde, J., Fernandes, S. M., Fernández-Bedoya, C., Francia, D., Franco, D., Fischer, V., Franke, A. J., Franke, M., Furuta, H., Garcia, F., Garcia, J., Gil-Botella, I., Giot, L., Givaudan, A., Göger-Neff, M., Gomez, H., Gonzalez, L. F. G., Goodenough, L., Goodman, M. C., Goon, J., Gramlich, B., Greiner, D., Guertin, A., Guillon, B., Habib, S. M., Haddad, Y., Hara, T., Hartmann, F. X., Hartnell, J., Haser, J., Hatzikoutelis, A., Hellwig, D., Hervé, S., Hofacker, R., Horton-Smith, G., Hourlier, A., Ishitsuka, M., Jänner, K., Jiménez, S., Jochum, J., Jollet, C., Kaether, F., Kale, K., Kalousis, L., Kamyshkov, Y., Kaneda, M., Kaplan, D. M., Karakac, M., Kawasaki, T., Kemp, E., Kibe, Y., Kirchner, T., Konno, T., Kryn, D., Kutter, T., Kuze, M., Lachenmaier, T., Lane, C. E., Langbrandtner, C., Lasserre, T., Lastoria, C., Latron, L., Leonardo, C., Letourneau, A., Lhuillier, D., Lima, Jr, H. P., Lindner, M., López-Castaño, J. M., LoSecco, J. M., Lubsandorzhiev, B., Lucht, S., Maeda, J., Maesano, C. N., Mariani, C., Maricic, J., Marie, F., Martinez, J. J., Martino, J., Matsubara, T., McKee, D., Meigner, F., Mention, G., Meregaglia, A., Meyer, J. P., Miletic, T., Milincic, R., Millot, J. F., Minotti, A., Mirones, V., Miyata, H., Mueller, Th. A., Nagasaka, Y., Nakajima, K., Navas-Nicolás, D., Nikitenko, Y., Novella, P., Oberauer, L., Obolensky, M., Onillon, A., Oralbaev, A., Ostrovskiy, I., Palomares, C., Peeters, S. J. M., Pepe, I. M., Perasso, S., Perrin, P., Pfahler, P., Porta, A., Pronost, G., Puras, J. C., Quéval, R., Ramirez, J. L., Reichenbacher, J., Reinhold, B., Reissfelder, M., Remoto, A., Reyna, D., Rodriguez, I., Röhling, M., Roncin, R., Rudolf, N., Rybolt, B., Sakamoto, Y., Santorelli, R., Sato, F., Schwan, U., Schönert, S., Schoppmann, S., Scola, L., Settimo, M., Shaevitz, M. A., Sharankova, R., Sibille, V., Sida, J.-L., Sinev, V., Shrestha, D., Skorokhvatov, M., Soldin, P., Spitz, J., Stahl, A., Stancu, I., Starzynski, P., Stock, M. R., Stokes, L. F. F., Strait, M., Stüken, A., Suekane, F., Sukhotin, S., Sumiyoshi, T., Sun, Y., Sun, Z., Svoboda, R., Tabata, H., Tamura, N., Terao, K., Tonazzo, A., Toral, F., Toups, M., Thi, H. Trinh, Valdivia, F., Valdiviesso, G., Vassilopoulos, N., Verdugo, A., Veyssiere, C., Viaud, B., Vignaud, D., Vivier, M., Wagner, S., Wiebusch, C., White, B., Winslow, L., Worcester, M., Wurm, M., Wurtz, J., Yang, G., Yáñez, J., Yermia, F., and Zbiri, K.
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- 2022
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32. Evaluating growth and intrinsic water-use efficiency in hardwood and conifer mixed plantations
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Gentilesca, Tiziana, Battipaglia, Giovanna, Borghetti, Marco, Colangelo, Michele, Altieri, Simona, Ferrara, Agostino M. S., Lapolla, Antonio, Rita, Angelo, and Ripullone, Francesco
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- 2021
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33. Conditional Recurrence-Free Survival after Oncologic Extended Resection for Gallbladder Cancer: An International Multicenter Analysis
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Vega, Eduardo A., Newhook, Timothy E., Kawaguchi, Yoshikuni, Qiao, Wei, De Bellis, Mario, Okuno, Masayuki, Panettieri, Elena, Nishino, Hiroto, Duwe, Gregor, Piccino, Marco, De Rose, Agostino M., Ruzzenente, Andrea, Uemoto, Shinji, Vivanco, Marcelo, Chun, Yun Shin, Cao, Hop S. Tran, Tzeng, Ching-Wei D., De Aretxabala, Xabier, Seo, Satoru, Giuliante, Felice, Guglielmi, Alfredo, Vinuela, Eduardo, and Vauthey, Jean-Nicolas
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- 2021
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34. The new Italian SIDAPA Baseline Series for patch testing (2023): an update according to the new regulatory pathway for contact allergens
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Luca, S, Leonardo, B, S, C, Fortina Anna, B, Francesca, C, Monica, C, Alessandro, B, Rosella, G, Ilaria, T, M, F, Andrea, B, Fabrizio, G, Emanuela, M, Maddalena, N, Lucia Mario, D, Cataldo, P, Luigi, B, Paolo, R, Caterina, F, Marta, T, Rossella, M, Giuseppe, A, Katharina, H, Abategiovanni, L, Albertazzi, D, Ali Biglu Marash, S, Amendolagine, G, Angelini, G, Annunziata, A, Assalve, D, Ayala, F, Babino, G, Barruscotti, S, Battista, T, Berta, M, Biondi, F, Boccaletti, V, Bonamonte, D, Bruni, F, Buffon, R, Caccavale, S, Calabrese, L, Calzavara Pinton, P, Camela, E, Carugno, A, Casciola, G, Cecchini, E, Cristaudo, A, D'Agostino, M, Damiani, G, Danese, P, Dattola, A, DE Salvo, V, Errichetti, E, Esposito, G, Esposito, M, Fantini, C, Fontana, E, Fornaro, L, Adina Frasin, L, Galeotti, T, Gasparini, G, Genco, L, Gravante, M, Guastaferro, D, Guerrasio, G, Guerriero, L, Lauro, W, Lucagnano, G, Malatesta, N, Desmond Mandel, V, Marano, L, Marino, V, Martora, F, Menna, L, Miano, C, Miccio, L, Michelerio, A, Milanesi, N, Monfrecola, G, Motolese, A, Nocerino, M, Noto, M, Ornielli, M, Pacifico, A, Papini, M, Pasolini, G, Penchini, L, Perazzolli, G, Peserico, A, Piccolo, V, Pigatto, P, Potestio, L, Pugliese, A, Recalcati, S, Rivetti, N, Rossi, M, Russo, F, Russo, T, Schena, D, Sensini, C, Tesauri, D, Marco Tomassini, G, Ventura, V, Venturini, M, Vezzoli, P, Vincenzi, C, Stingeni Luca, Bianchi Leonardo, Caroppo Elena S, Belloni Fortina Anna, Caroppo Francesca, Corazza Monica, Borghi Alessandro, Gallo Rosella, Trave Ilaria, Ferrucci Silvia M, Beretta Andrea, Guarneri Fabrizio, Martina Emanuela, Napolitano Maddalena, De Lucia Mario, Patruno Cataldo, Bennardo Luigi, Romita Paolo, Foti Caterina, Tramontana Marta, Marietti Rossella, Argenziano Giuseppe, Hansel Katharina, Luisa Abategiovanni, Donatella Albertazzi, Samane Ali Biglu Marash, Graziana Amendolagine, Gianni Angelini, Alberto Annunziata, Danilo Assalve, Fabio Ayala, Graziella Babino, Stefania Barruscotti, Teresa Battista, Mauro Berta, Filippo Biondi, Valeria Boccaletti, Domenico Bonamonte, Francesca Bruni, Rosana Buffon, Stefano Caccavale, Laura Calabrese, Piergiacomo Calzavara Pinton, Elisa Camela, Andrea Carugno, Gabriele Casciola, Elisa Cecchini, Antonio Cristaudo, Michela D'Agostino, Giovanni Damiani, Pietro Danese, Annunziata Dattola, Vincenzo DE Salvo, Enzo Errichetti, Gianluca Esposito, Maria Esposito, Carolina Fantini, Elena Fontana, Luigi Fornaro, Lucretia Adina Frasin, Tommaso Galeotti, Giulia Gasparini, Lucia Genco, Massimo Gravante, Donatella Guastaferro, Gianluca Guerrasio, Luigi Guerriero, Wanda Lauro, Gioacchino Lucagnano, Nicolò Malatesta, Victor Desmond Mandel, Laura Marano, Vincenzo Marino, Fabrizio Martora, Luca Menna, Chiara Miano, Laura Miccio, Andrea Michelerio, Nicola Milanesi, Giuseppe Monfrecola, Alberico Motolese, Mariateresa Nocerino, Matteo Noto, Matteo Ornielli, Alessia Pacifico, Manuela Papini, Giorgio Pasolini, Luca Penchini, Gabriele Perazzolli, Andrea Peserico, Vincenzo Piccolo, Paolo Pigatto, Luca Potestio, Antonio Pugliese, Sebastiano Recalcati, Nicolò Rivetti, Mariateresa Rossi, Filomena Russo, Teresa Russo, Donatella Schena, Chiara Sensini, David Tesauri, Gian Marco Tomassini, Virginia Ventura, Marina Venturini, Pamela Vezzoli, Colombina Vincenzi, Luca, S, Leonardo, B, S, C, Fortina Anna, B, Francesca, C, Monica, C, Alessandro, B, Rosella, G, Ilaria, T, M, F, Andrea, B, Fabrizio, G, Emanuela, M, Maddalena, N, Lucia Mario, D, Cataldo, P, Luigi, B, Paolo, R, Caterina, F, Marta, T, Rossella, M, Giuseppe, A, Katharina, H, Abategiovanni, L, Albertazzi, D, Ali Biglu Marash, S, Amendolagine, G, Angelini, G, Annunziata, A, Assalve, D, Ayala, F, Babino, G, Barruscotti, S, Battista, T, Berta, M, Biondi, F, Boccaletti, V, Bonamonte, D, Bruni, F, Buffon, R, Caccavale, S, Calabrese, L, Calzavara Pinton, P, Camela, E, Carugno, A, Casciola, G, Cecchini, E, Cristaudo, A, D'Agostino, M, Damiani, G, Danese, P, Dattola, A, DE Salvo, V, Errichetti, E, Esposito, G, Esposito, M, Fantini, C, Fontana, E, Fornaro, L, Adina Frasin, L, Galeotti, T, Gasparini, G, Genco, L, Gravante, M, Guastaferro, D, Guerrasio, G, Guerriero, L, Lauro, W, Lucagnano, G, Malatesta, N, Desmond Mandel, V, Marano, L, Marino, V, Martora, F, Menna, L, Miano, C, Miccio, L, Michelerio, A, Milanesi, N, Monfrecola, G, Motolese, A, Nocerino, M, Noto, M, Ornielli, M, Pacifico, A, Papini, M, Pasolini, G, Penchini, L, Perazzolli, G, Peserico, A, Piccolo, V, Pigatto, P, Potestio, L, Pugliese, A, Recalcati, S, Rivetti, N, Rossi, M, Russo, F, Russo, T, Schena, D, Sensini, C, Tesauri, D, Marco Tomassini, G, Ventura, V, Venturini, M, Vezzoli, P, Vincenzi, C, Stingeni Luca, Bianchi Leonardo, Caroppo Elena S, Belloni Fortina Anna, Caroppo Francesca, Corazza Monica, Borghi Alessandro, Gallo Rosella, Trave Ilaria, Ferrucci Silvia M, Beretta Andrea, Guarneri Fabrizio, Martina Emanuela, Napolitano Maddalena, De Lucia Mario, Patruno Cataldo, Bennardo Luigi, Romita Paolo, Foti Caterina, Tramontana Marta, Marietti Rossella, Argenziano Giuseppe, Hansel Katharina, Luisa Abategiovanni, Donatella Albertazzi, Samane Ali Biglu Marash, Graziana Amendolagine, Gianni Angelini, Alberto Annunziata, Danilo Assalve, Fabio Ayala, Graziella Babino, Stefania Barruscotti, Teresa Battista, Mauro Berta, Filippo Biondi, Valeria Boccaletti, Domenico Bonamonte, Francesca Bruni, Rosana Buffon, Stefano Caccavale, Laura Calabrese, Piergiacomo Calzavara Pinton, Elisa Camela, Andrea Carugno, Gabriele Casciola, Elisa Cecchini, Antonio Cristaudo, Michela D'Agostino, Giovanni Damiani, Pietro Danese, Annunziata Dattola, Vincenzo DE Salvo, Enzo Errichetti, Gianluca Esposito, Maria Esposito, Carolina Fantini, Elena Fontana, Luigi Fornaro, Lucretia Adina Frasin, Tommaso Galeotti, Giulia Gasparini, Lucia Genco, Massimo Gravante, Donatella Guastaferro, Gianluca Guerrasio, Luigi Guerriero, Wanda Lauro, Gioacchino Lucagnano, Nicolò Malatesta, Victor Desmond Mandel, Laura Marano, Vincenzo Marino, Fabrizio Martora, Luca Menna, Chiara Miano, Laura Miccio, Andrea Michelerio, Nicola Milanesi, Giuseppe Monfrecola, Alberico Motolese, Mariateresa Nocerino, Matteo Noto, Matteo Ornielli, Alessia Pacifico, Manuela Papini, Giorgio Pasolini, Luca Penchini, Gabriele Perazzolli, Andrea Peserico, Vincenzo Piccolo, Paolo Pigatto, Luca Potestio, Antonio Pugliese, Sebastiano Recalcati, Nicolò Rivetti, Mariateresa Rossi, Filomena Russo, Teresa Russo, Donatella Schena, Chiara Sensini, David Tesauri, Gian Marco Tomassini, Virginia Ventura, Marina Venturini, Pamela Vezzoli, and Colombina Vincenzi
- Abstract
Allergic contact dermatitis (ACD) is a common inflammatory skin disease caused by delayed hypersensitivity to chemical and biotic contact allergens. ACD significantly affects the patients' quality of life negatively impacting both occupational and non-occupational settings. Patch testing is the gold standard diagnostic in vivo test to precise the ACD etiology and to correctly perform prevention. According to the Italian Medicines Agency (AIFA) legislative decree no. 178 of 29th May 1991, allergens are defined as medicines and therefore they are subject to strict regulation. In 2017, AIFA (decree no. 2130/2017) started a procedure to regulate contact allergens on the Italian market and actually the contact allergens temporarily authorized are reported in AIFA decree no. 98/2022, valid until November 2023. The availability on the market of contact allergens to diagnose ACD and continuous updating on the basis of new epidemiological trends are mandatory, jointly with the continuous update of the baseline and integrative series for patch testing. For this reason, the scientific community represented in Italy by the Skin Allergies Study Group of SIDeMaST (Italian Society of Dermatology and Venereology) and SIDAPA (Italian Society of Allergological, Occupational and Environmental Dermatology) are constantly working, in close relationship with the European scientific communities with large expertise in this important sector of the modern Dermatology. Herein, we report the setting up of regulatory legislation by AIFA and the new Italian Adult Baseline Series for patch testing.
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- 2024
35. How audit&feedback can bridge the gap between scientific evidence and clinical practice: reflections from the EASY-NET network programme
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De Belvis, Antonio, Acampora, Anna, D'Agostino, M., Angioletti, C., Colais, P., Agabiti, N., Davoli, Marina, de Belvis A. (ORCID:0000-0003-4456-1937), Acampora A., Davoli M., De Belvis, Antonio, Acampora, Anna, D'Agostino, M., Angioletti, C., Colais, P., Agabiti, N., Davoli, Marina, de Belvis A. (ORCID:0000-0003-4456-1937), Acampora A., and Davoli M.
- Abstract
Il divario tra ricerca e pratica si riferisce ai casi in cui la ricerca fatica a essere applicabile in contesti concreti, come quello sanitario, con un notevole impatto sull’organizzazione dell’assistenza, sull’erogazione dei servizi e sugli esiti di salute. Questo aspetto si somma, nei sistemi sanitari come quello italiano, a una forte variabilità nell’accesso ad assistenza di qualità e negli esiti di salute tra le Regioni e nello stesso territorio. Viene usata l’espressione “trasferimento della conoscenza”1 per spiegare il processo iterativo di sintesi e scambio dai risultati della ricerca sanitaria al miglioramento della qualità nella pratica clinica. Comprendere e applicare tutto ciò risulta essenziale per implementare con tempestività ed efficacia le evidenze scientifiche.
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- 2024
36. Charged particle decay of hot and rotating $^{88}$Mo nuclei in fusion-evaporation reactions
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Valdré, S., Piantelli, S., Casini, G., Barlini, S., Carboni, S., Ciemała, M., Kmiecik, M., Maj, A., Mazurek, K., Cinausero, M., Gramegna, F., Kravchuk, V. L., Morelli, L., Marchi, T., Baiocco, G., Bardelli, L., Bednarczyk, P., Benzoni, G., Bini, M., Blasi, N., Bracco, A., Brambilla, S., Bruno, M., Camera, F., Chbihi, A., Corsi, A., Crespi, F. C. L., D'Agostino, M., Degerlier, M., Fabris, D., Fornal, B., Giaz, A., Krzysiek, M., Leoni, S., Matejska-Minda, M., Mazumdar, I., Mȩczyński, W., Million, B., Montanari, D., Myalski, S., Nicolini, R., Olmi, A., Pasquali, G., Prete, G., Roberts, O. J., Styczeń, J., Szpak, B., Wasilewska, B., Wieland, O., Wieleczko, J. P., and Ziȩbliński, M.
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Nuclear Experiment - Abstract
A study of fusion-evaporation and (partly) fusion-fission channels for the $^{88}$Mo compound nucleus, produced at different excitation energies in the reaction $^{48}$Ti + $^{40}$Ca at 300, 450 and 600 MeV beam energies, is presented. Fusion-evaporation and fusion-fission cross sections have been extracted and compared with the existing systematics. Experimental data concerning light charged particles have been compared with the prediction of the statistical model in its implementation in the Gemini++ code, well suited even for high spin systems, in order to tune the main model parameters in a mass region not abundantly covered by exclusive experimental data. Multiplicities for light charged particles emitted in fusion evaporation events are also presented. Some discrepancies with respect to the prediction of the statistical model have been found for forward emitted $\alpha$-particles; they may be due both to pre-equilibrium emission and to reaction channels (such as Deep Inelastic Collisions, QuasiFission/QuasiFusion) different from the compound nucleus formation., Comment: 14 pages, 14 figures
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- 2015
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37. Emerging Prognostic Markers in Patients Undergoing Liver Resection for Hepatocellular Carcinoma: A Narrative Review.
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Panettieri, Elena, Campisi, Andrea, De Rose, Agostino M., Mele, Caterina, Giuliante, Felice, Vauthey, Jean-Nicolas, and Ardito, Francesco
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CANCER relapse ,NUTRITIONAL assessment ,GENETIC markers ,ASPARTATE aminotransferase ,LYMPHOCYTE count ,NEUTROPHILS ,TUMOR markers ,BODY fluid examination ,TREATMENT effectiveness ,BLOOD cell count ,GENE expression profiling ,ALANINE aminotransferase ,HEPATECTOMY ,INFLAMMATION ,HEPATOCELLULAR carcinoma ,MEDICAL care costs ,OVERALL survival ,DISEASE risk factors - Abstract
Simple Summary: Hepatocellular carcinoma (HCC) is a primary tumor of the liver with a particularly high incidence in Asia. HCC has a tendency to recur despite curative-intent liver resection, and new reliable prognostic markers would have high clinical relevance. Liquid biopsy markers, gene signatures, and inflammation markers represent valuable tools to predict recurrence and overall survival in patients undergoing hepatectomy for HCC. Nevertheless, while some of the proposed new markers have been widely investigated and demonstrated to be reproducible, others seem less reproducible in clinical practice. In particular, liquid biopsy is a powerful tool for predicting long-term outcomes after resection of HCC; with costs related to its technical implementation representing a major limitation. More reports from Western countries are necessary to corroborate the evidence. In patients with hepatocellular carcinoma (HCC), liver resection is potentially curative. Nevertheless, post-operative recurrence is common, occurring in up to 70% of patients. Factors traditionally recognized to predict recurrence and survival after liver resection for HCC include pathologic factors (i.e., microvascular and capsular invasion) and an increase in alpha-fetoprotein level. During the past decade, many new markers have been reported to correlate with prognosis after resection of HCC: liquid biopsy markers, gene signatures, inflammation markers, and other biomarkers, including PIVKA-II, immune checkpoint molecules, and proteins in urinary exosomes. However, not all of these new markers are readily available in clinical practice, and their reproducibility is unclear. Liquid biopsy is a powerful and established tool for predicting long-term outcomes after resection of HCC; the main limitation of liquid biopsy is represented by the cost related to its technical implementation. Numerous patterns of genetic expression capable of predicting survival after curative-intent hepatectomy for HCC have been identified, but published findings regarding these markers are heterogenous. Inflammation markers in the form of prognostic nutritional index and different blood cell ratios seem more easily reproducible and more affordable on a large scale than other emerging markers. To select the most effective treatment for patients with HCC, it is crucial that the scientific community validate new predictive markers for recurrence and survival after resection that are reliable and widely reproducible. More reports from Western countries are necessary to corroborate the evidence. [ABSTRACT FROM AUTHOR]
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- 2024
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38. Metformin exerts anti-cancerogenic effects and reverses epithelial-to-mesenchymal transition trait in primary human intrahepatic cholangiocarcinoma cells
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Sabina Di Matteo, Lorenzo Nevi, Diletta Overi, Nadine Landolina, Jessica Faccioli, Federico Giulitti, Chiara Napoletano, Andrea Oddi, Augusto M. Marziani, Daniele Costantini, Agostino M. De Rose, Fabio Melandro, Maria C. Bragazzi, Gian Luca Grazi, Pasquale B. Berloco, Felice Giuliante, Giuseppe Donato, Lorenzo Moretta, Guido Carpino, Vincenzo Cardinale, Eugenio Gaudio, and Domenico Alvaro
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Medicine ,Science - Abstract
Abstract Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive cancer with marked resistance to chemotherapeutics without therapies. The tumour microenvironment of iCCA is enriched of Cancer-Stem-Cells expressing Epithelial-to-Mesenchymal Transition (EMT) traits, being these features associated with aggressiveness and drug resistance. Treatment with the anti-diabetic drug Metformin, has been recently associated with reduced incidence of iCCA. We aimed to evaluate the anti-cancerogenic effects of Metformin in vitro and in vivo on primary cultures of human iCCA. Our results showed that Metformin inhibited cell proliferation and induced dose- and time-dependent apoptosis of iCCA. The migration and invasion of iCCA cells in an extracellular bio-matrix was also significantly reduced upon treatments. Metformin increased the AMPK and FOXO3 and induced phosphorylation of activating FOXO3 in iCCA cells. After 12 days of treatment, a marked decrease of mesenchymal and EMT genes and an increase of epithelial genes were observed. After 2 months of treatment, in order to simulate chronic administration, Cytokeratin-19 positive cells constituted the majority of cell cultures paralleled by decreased Vimentin protein expression. Subcutaneous injection of iCCA cells previously treated with Metformin, in Balb/c-nude mice failed to induce tumour development. In conclusion, Metformin reverts the mesenchymal and EMT traits in iCCA by activating AMPK-FOXO3 related pathways suggesting it might have therapeutic implications.
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- 2021
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39. Thermal properties of light nuclei from $^{12}$C+$^{12}$C fusion-evaporation reactions
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Morelli, L, Baiocco, G, D'Agostino, M, Gulminelli, F, Bruno, M, Abbondanno, U, Appannababu, S, Barlini, S, Bini, M, Casini, G, Cinausero, M, Degerlier, M, Fabris, D, Gelli, N, Gramegna, F, Kravchuk, V L, Marchi, T, Pasquali, G, Piantelli, S, Valdré, S, and Raduta, Ad R
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Nuclear Experiment - Abstract
The $^{12}$C+$^{12}$C reaction at 95 MeV has been studied through the complete charge identification of its products by means of the GARFIELD+RCo experimental set-up at INFN Laboratori Nazionali di Legnaro (LNL). In this paper, the first of a series of two, a comparison to a dedicated Hauser-Feshbach calculation allows to select a set of dissipative events which corresponds, to a large extent, to the statistical evaporation of highly excited $^{24}$Mg. Information on the isotopic distribution of the evaporation residues in coincidence with their complete evaporation chain is also extracted. The set of data puts strong constraints on the behaviour of the level density of light nuclei above the threshold for particle emission. In particular, a fast increase of the level density parameter with excitation energy is supported by the data. Residual deviations from a statistical behaviour are seen in two specific channels, and tentatively associated with a contamination from direct reactions and/or $\alpha$-clustering effects. These channels are studied in further details in the second paper of the series., Comment: 24 pages, 15 figures, first paper of a series of two
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- 2014
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40. Non-statistical decay and $\alpha$-correlations in the $^{12}$C+$^{12}$C fusion-evaporation reaction at 95 MeV
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Morelli, L., Baiocco, G., D'Agostino, M., Gulminelli, F., Bruno, M., Abbondanno, U., Appannababu, S., Barlini, S., Bini, M., Casini, G., Cinausero, M., Degerlier, M., Fabris, D., Gelli, N., Gramegna, F., Kravchuk, V. L., Marchi, T., Pasquali, G., Piantelli, S., Valdré, S., and Raduta, Ad R.
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Nuclear Experiment - Abstract
Multiple alpha coincidence and correlations are studied in the reaction $^{12}$C+$^{12}$C at 95 MeV for fusion-evaporation events completely detected in charge. Two specific channels with Carbon and Oxygen residues in coincidence with $\alpha$-particles are addressed, which are associated with anomalously high branching ratios with respect the predictions by Hauser-Feshbach calculations. Triple alpha emission appears kinematically compatible with a sequential emission from a highly excited Mg. The phase space distribution of $\alpha$-$\alpha$ coincidences suggests a correlated emission from a Mg compound, leaving an Oxygen residue excited above the threshold for neutron decay. These observations indicate a preferential $\alpha$ emission of $^{24}$Mg at excitation energies well above the threshold for $6-\alpha$ decay., Comment: 21 pages, 17 figures, second paper of a series of two
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- 2014
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41. Metformin exerts anti-cancerogenic effects and reverses epithelial-to-mesenchymal transition trait in primary human intrahepatic cholangiocarcinoma cells
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Di Matteo, Sabina, Nevi, Lorenzo, Overi, Diletta, Landolina, Nadine, Faccioli, Jessica, Giulitti, Federico, Napoletano, Chiara, Oddi, Andrea, Marziani, Augusto M., Costantini, Daniele, De Rose, Agostino M., Melandro, Fabio, Bragazzi, Maria C., Grazi, Gian Luca, Berloco, Pasquale B., Giuliante, Felice, Donato, Giuseppe, Moretta, Lorenzo, Carpino, Guido, Cardinale, Vincenzo, Gaudio, Eugenio, and Alvaro, Domenico
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- 2021
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42. Chronic related group classification system as a new public health tool to predict risk and outcome of COVID-19 in patients with systemic rheumatic diseases: A population-based study of more than forty thousand patients
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De Lorenzis, E., Parente, Paolo, Natalello, G., Soldati, S., Bosello, Silvia Laura, Barbara, A., Sorge, C., Axelrod, S., Verardi, Lucrezia, Cerasuolo, Pier Giacomo, Peluso, Giusy, Gemma, A., Davoli, Marina, Biliotti, D., Bruzzese, Vincenzo, Goletti, M., Di Martino, M., D'Agostino, M. A., De Lorenzis E., Parente P., Natalello G., Soldati S., Bosello S. L. (ORCID:0000-0002-4837-447X), Barbara A., Sorge C., Axelrod S., Verardi L., Cerasuolo P. G., Peluso G., Gemma A., Davoli M., Biliotti D., Bruzzese V., Goletti M., Di Martino M., D'Agostino M. A., De Lorenzis, E., Parente, Paolo, Natalello, G., Soldati, S., Bosello, Silvia Laura, Barbara, A., Sorge, C., Axelrod, S., Verardi, Lucrezia, Cerasuolo, Pier Giacomo, Peluso, Giusy, Gemma, A., Davoli, Marina, Biliotti, D., Bruzzese, Vincenzo, Goletti, M., Di Martino, M., D'Agostino, M. A., De Lorenzis E., Parente P., Natalello G., Soldati S., Bosello S. L. (ORCID:0000-0002-4837-447X), Barbara A., Sorge C., Axelrod S., Verardi L., Cerasuolo P. G., Peluso G., Gemma A., Davoli M., Biliotti D., Bruzzese V., Goletti M., Di Martino M., and D'Agostino M. A.
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- 2023
43. The provisional OMERACT ultrasonography score for giant cell arteritis
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Dejaco, C, Ponte, C, Monti, S, Rozza, D, Scire, C, Terslev, L, Bruyn, G, Boumans, D, Hartung, W, Hocevar, A, Milchert, M, Dohn, U, Mukhtyar, C, Aschwanden, M, Bosch, P, Camellino, D, Chrysidis, S, Ciancio, G, D'Agostino, M, Daikeler, T, Dasgupta, B, De Miguel, E, Diamantopoulos, A, Duftner, C, Agueda, A, Fredberg, U, Hanova, P, Hansen, I, Hauge, E, Iagnocco, A, Inanc, N, Juche, A, Karalilova, R, Kawamoto, T, Keller, K, Keen, H, Kermani, T, Kohler, M, Koster, M, Luqmani, R, Macchioni, P, Mackie, S, Naredo, E, Nielsen, B, Ogasawara, M, Pineda, C, Schafer, V, Seitz, L, Tomelleri, A, Torralba, K, Van Der Geest, K, Warrington, K, Schmidt, W, Dejaco C., Ponte C., Monti S., Rozza D., Scire C. A., Terslev L., Bruyn G. A. W., Boumans D., Hartung W., Hocevar A., Milchert M., Dohn U. Mo., Mukhtyar C. B., Aschwanden M., Bosch P., Camellino D., Chrysidis S., Ciancio G., D'Agostino M. A., Daikeler T., Dasgupta B., De Miguel E., Diamantopoulos A. P., Duftner C., Agueda A., Fredberg U., Hanova P., Hansen I. To., Hauge E. -M., Iagnocco A., Inanc N., Juche A., Karalilova R., Kawamoto T., Keller K. K., Keen H. I., Kermani T. A., Kohler M. J., Koster M., Luqmani R. A., Macchioni P., Mackie S. L., Naredo E., Nielsen B. D., Ogasawara M., Pineda C., Schafer V. S., Seitz L., Tomelleri A., Torralba K. D., Van Der Geest K. S. M., Warrington K. J., Schmidt W. A., Dejaco, C, Ponte, C, Monti, S, Rozza, D, Scire, C, Terslev, L, Bruyn, G, Boumans, D, Hartung, W, Hocevar, A, Milchert, M, Dohn, U, Mukhtyar, C, Aschwanden, M, Bosch, P, Camellino, D, Chrysidis, S, Ciancio, G, D'Agostino, M, Daikeler, T, Dasgupta, B, De Miguel, E, Diamantopoulos, A, Duftner, C, Agueda, A, Fredberg, U, Hanova, P, Hansen, I, Hauge, E, Iagnocco, A, Inanc, N, Juche, A, Karalilova, R, Kawamoto, T, Keller, K, Keen, H, Kermani, T, Kohler, M, Koster, M, Luqmani, R, Macchioni, P, Mackie, S, Naredo, E, Nielsen, B, Ogasawara, M, Pineda, C, Schafer, V, Seitz, L, Tomelleri, A, Torralba, K, Van Der Geest, K, Warrington, K, Schmidt, W, Dejaco C., Ponte C., Monti S., Rozza D., Scire C. A., Terslev L., Bruyn G. A. W., Boumans D., Hartung W., Hocevar A., Milchert M., Dohn U. Mo., Mukhtyar C. B., Aschwanden M., Bosch P., Camellino D., Chrysidis S., Ciancio G., D'Agostino M. A., Daikeler T., Dasgupta B., De Miguel E., Diamantopoulos A. P., Duftner C., Agueda A., Fredberg U., Hanova P., Hansen I. To., Hauge E. -M., Iagnocco A., Inanc N., Juche A., Karalilova R., Kawamoto T., Keller K. K., Keen H. I., Kermani T. A., Kohler M. J., Koster M., Luqmani R. A., Macchioni P., Mackie S. L., Naredo E., Nielsen B. D., Ogasawara M., Pineda C., Schafer V. S., Seitz L., Tomelleri A., Torralba K. D., Van Der Geest K. S. M., Warrington K. J., and Schmidt W. A.
- Abstract
Objectives To develop an Outcome Measures in Rheumatology (OMERACT) ultrasonography score for monitoring disease activity in giant cell arteritis (GCA) and evaluate its metric properties. Methods The OMERACT Instrument Selection Algorithm was followed. Forty-nine members of the OMERACT ultrasonography large vessel vasculitis working group were invited to seven Delphi rounds. An online reliability exercise was conducted using images of bilateral common temporal arteries, parietal and frontal branches as well as axillary arteries from 16 patients with GCA and 7 controls. Sensitivity to change and convergent construct validity were tested using data from a prospective cohort of patients with new GCA in which ultrasound-based intima-media thickness (IMT) measurements were conducted at weeks 1, 3, 6, 12 and 24. Results Agreement was obtained (92.7%) for the OMERACT GCA Ultrasonography Score (OGUS), calculated as follows: sum of IMT measured in every segment divided by the rounded cut-off values of IMTs in each segment. The resulting value is then divided by the number of segments available. Thirty-five members conducted the reliability exercise, the interrater intraclass correlation coefficient (ICC) for the OGUS was 0.72-0.84 and the median intrareader ICC was 0.91. The prospective cohort consisted of 52 patients. Sensitivity to change between baseline and each follow-up visit up to week 24 yielded standardised mean differences from -1.19 to -2.16, corresponding to large and very large magnitudes of change, respectively. OGUS correlated moderately with erythrocyte sedimentation rate, C reactive protein and Birmingham Vasculitis Activity Score (corr coeff 0.37-0.48). Conclusion We developed a provisional OGUS for potential use in clinical trials.
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- 2023
44. Which are the most frequently involved peripheral joints in calcium pyrophosphate crystal deposition at imaging? A systematic literature review and meta-analysis by the OMERACT ultrasound – CPPD subgroup
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Adinolfi, A, Sirotti, S, Sakellariou, G, Cipolletta, E, Filippucci, E, Porta, F, Zanetti, A, Ughi, N, Sarzi-Puttini, P, Scire, C, Keen, H, Pineda, C, Terslev, L, D'Agostino, M, Filippou, G, Adinolfi A., Sirotti S., Sakellariou G., Cipolletta E., Filippucci E., Porta F., Zanetti A., Ughi N., Sarzi-Puttini P., Scire C. A., Keen H., Pineda C., Terslev L., D'Agostino M. A., Filippou G., Adinolfi, A, Sirotti, S, Sakellariou, G, Cipolletta, E, Filippucci, E, Porta, F, Zanetti, A, Ughi, N, Sarzi-Puttini, P, Scire, C, Keen, H, Pineda, C, Terslev, L, D'Agostino, M, Filippou, G, Adinolfi A., Sirotti S., Sakellariou G., Cipolletta E., Filippucci E., Porta F., Zanetti A., Ughi N., Sarzi-Puttini P., Scire C. A., Keen H., Pineda C., Terslev L., D'Agostino M. A., and Filippou G.
- Abstract
Objectives: To identify the prevalence of calcium pyrophosphate crystal deposition (CPPD) using ultrasound and conventional radiology at peripheral joints in patients with suspected or definite CPPD. Methods: A systematic literature search was performed in PubMed and Embase using pre-defined search strategies from inception to April 2021 to identify studies that evaluated conventional radiology and ultrasound in detecting CPPD at peripheral joints, including definite or suspected CPPD [Research question 1 (RQ1) and Research Question 2 (RQ2), respectively]. For the meta-analysis, the first, second, and third sub-analysis included studies with the knee, and knee or wrist as the index joint for CPPD (without restrictions on the reference standard) and synovial fluid analysis or histology as a reference standard (without restrictions on the index joint), respectively. Results: One-thousand eight hundred and twenty-seven manuscripts were identified, of which 94 articles were finally included. Twenty-two and seventy-two papers were included in RQ1 and RQ2, respectively. The knee had the highest prevalence for RQ1 and RQ2 by both conventional radiology and ultrasound, followed by the wrist with the highest prevalence for RQ1. The hand had the lowest CPPD prevalence. The third sub-analysis showed a higher CPPD prevalence on ultrasound than conventional radiology at the knee (only data available). Conclusion: Among all peripheral joints, the knees and wrists could be regarded as the target joints for CPPD detection by imaging. Furthermore, ultrasound seems to detect a higher number of calcium pyrophosphate deposits than conventional radiology, even when using a more restrictive reference standard.
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- 2023
45. Reliability and diagnostic accuracy of radiography for the diagnosis of calcium pyrophosphate deposition: performance of the novel definitions developed by an international multidisciplinary working group
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Sirotti, S, Becce, F, Sconfienza, L, Terslev, L, Naredo, E, Zufferey, P, Pineda, C, Gutierrez, M, Adinolfi, A, Serban, T, Maccarter, D, Mouterde, G, Zanetti, A, Scanu, A, Moller, I, Novo-Rivas, U, Largo, R, Sarzi-Puttini, P, Abhishek, A, Choi, H, Dalbeth, N, Pascart, T, Tedeschi, S, D'Agostino, M, Iagnocco, A, Keen, H, Scire, C, Filippou, G, Sirotti S., Becce F., Sconfienza L. M., Terslev L., Naredo E., Zufferey P., Pineda C., Gutierrez M., Adinolfi A., Serban T., MacCarter D., Mouterde G., Zanetti A., Scanu A., Moller I., Novo-Rivas U., Largo R., Sarzi-Puttini P., Abhishek A., Choi H. K., Dalbeth N., Pascart T., Tedeschi S. K., D'Agostino M. -A., Iagnocco A., Keen H. I., Scire C. A., Filippou G., Sirotti, S, Becce, F, Sconfienza, L, Terslev, L, Naredo, E, Zufferey, P, Pineda, C, Gutierrez, M, Adinolfi, A, Serban, T, Maccarter, D, Mouterde, G, Zanetti, A, Scanu, A, Moller, I, Novo-Rivas, U, Largo, R, Sarzi-Puttini, P, Abhishek, A, Choi, H, Dalbeth, N, Pascart, T, Tedeschi, S, D'Agostino, M, Iagnocco, A, Keen, H, Scire, C, Filippou, G, Sirotti S., Becce F., Sconfienza L. M., Terslev L., Naredo E., Zufferey P., Pineda C., Gutierrez M., Adinolfi A., Serban T., MacCarter D., Mouterde G., Zanetti A., Scanu A., Moller I., Novo-Rivas U., Largo R., Sarzi-Puttini P., Abhishek A., Choi H. K., Dalbeth N., Pascart T., Tedeschi S. K., D'Agostino M. -A., Iagnocco A., Keen H. I., Scire C. A., and Filippou G.
- Abstract
Objectives: To assess the reliability and diagnostic accuracy of new radiographic definitions for calcium pyrophosphate deposition (CPPD) identification, developed by an international multidisciplinary working group. Methods: Patients with knee osteoarthritis scheduled for knee replacement were enrolled. Two radiologists and two rheumatologists assessed twice the images for presence/absence of CPPD on menisci, hyaline cartilage, tendons, joint capsule, synovial membrane, using the new definitions. In case of disagreement, a consensus decision was taken and considered for the assessment of diagnostic performance. Histological examination of specimens under compensated polarized light microscopy was the reference standard. Prevalence-adjusted bias-adjusted kappa (PABAK) was used to assess the reliability. Diagnostic performance statistics were calculated. Results: Sixty-seven participants were enrolled for the reliability study. The inter-observer reliability was substantial in most of the assessed structures when considering all 4 readers (kappa range 0.59 – 0.90), substantial to almost perfect among radiologists (kappa range 0.70-0.91), and moderate to almost perfect among rheumatologists (kappa range 0.46 – 0.88). The intra-observer reliability was substantial to almost perfect for all the observers (kappa range 0.70 – 1). Fifty-one patients were enrolled for the accuracy study. Radiography demonstrated to be specific for CPPD (92%), but sensitivity remained low in all sites and in the overall diagnosis (54%). Conclusion: The new imaging definitions of CPPD are highly specific against the gold standard of histological diagnosis; when described findings are present these definitions allow for a definite diagnosis of CPPD, rather than other calcium-containing crystal depositions; instead a negative finding does not exclude the diagnosis.
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- 2023
46. Tau/Charm Factory Accelerator Report
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Biagini, M. E., Boni, R., Boscolo, M., Chiarucci, A., Cimino, R., Clozza, A., Drago, A., Guiducci, S., Ligi, C., Mazzitelli, G., Ricci, R., Sanelli, C., Serio, M., Stella, A., Tomassini, S., Bini, S., Cioeta, F., Cittadino, D., D'Agostino, M., Del Franco, M., Piane, A. Delle, Di Pasquale, E., Frascadore, G., Gazzana, S., Gargana, R., Incremona, S., Michelotti, A., Sabbatini, L., Schillaci, G., Sedita, M., Raimondi, P., Petronzio, R., Paoloni, E., Liuzzo, S. M., Carmignani, N., and Pivi, M.
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Physics - Accelerator Physics - Abstract
The present Report concerns the current status of the Italian Tau/Charm accelerator project and in particular discusses the issues related to the lattice design, to the accelerators systems and to the associated conventional facilities. The project aims at realizing a variable energy Flavor Factory between 1 and 4.6 GeV in the center of mass, and succeeds to the SuperB project from which it inherits most of the solutions proposed in this document. The work comes from a cooperation involving the INFN Frascati National Laboratories accelerator experts, the young newcomers, mostly engineers, of the Cabibbo Lab consortium and key collaborators from external laboratories., Comment: 150 pages
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- 2013
47. Pre-equilibrium {\alpha}-particle emission as a probe to study {\alpha}-clustering in nuclei
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Fotina, O. V., Goncharov, S. A., Eremenko, D. O., Platonov, S. Yu., Yuminov, O. A., Kravchuk, V. L., Gramegna, F., Marchi, T., Cinausero, M., D'Agostino, M., Bruno, M., Baiocco, G., Morelli, L., Degerlier, M., Casini, G., Barlini, S., Valdrè, S., Piantelli, S., Pasquali, G., Bracco, A., Camera, F., Wieland, O., Benzoni, G., Blasi, N., Giaz, A., Corsi, A., and Fabris, D.
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Nuclear Experiment - Abstract
A theoretical approach was developed to describe secondary particle emission in heavy ion collisions, with special regards to pre-equilibrium {\alpha}-particle production. Griffin's model of non-equilibrium processes is used to account for the first stage of the compound system formation, while a Monte Carlo statistical approach was used to describe the further decay from a hot source at thermal equilibrium. The probabilities of neutron, proton and {\alpha}-particle emission have been evaluated for both the equilibrium and pre-equilibrium stages of the process. Fission and {\gamma}-ray emission competition were also considered after equilibration. Effects due the possible cluster structure of the projectile which has been excited during the collisions have been experimentally evidenced studying the double differential cross sections of p and {\alpha}-particles emitted in the E=250MeV 16O +116Sn reaction. Calculations within the present model with different clusterization probabilities have been compared to the experimental data., Comment: 4 pages, 6 figures
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- 2013
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48. GARFIELD + RCo Digital Upgrade: a Modern Set-up for Mass and Charge Identification of Heavy Ion Reaction Products
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Bruno, M., Gramegna, F., Marchi, T., Morelli, L., Pasquali, G., Casini, G., Abbondanno, U., Baiocco, G., Bardelli, L., Barlini, S., Bini, M., Carboni, S., Cinausero, M., Agostino, M. D, Degerlier, M., Kravchuk, V. L., Geraci, E., Mastinu, P. F., Ordine, A., Piantelli, S., Poggi, G., and Moroni, A.
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Physics - Instrumentation and Detectors ,Nuclear Experiment - Abstract
An upgraded GARFIELD + Ring Counter (RCo) apparatus is presented with improved performances as far as electronics and detectors are concerned. On one side fast sampling digital read out has been extended to all detectors, allowing for an important simplification of the signal processing chain together with an enriched extracted information. On the other side a relevant improvement has been made in the forward part of the setup (RCo): an increased granularity of the CsI(Tl) crystals and a higher homogeneity in the silicon detector resistivity. The renewed performances of the GARFIELD + RCo array make it suitable for nuclear reaction measurements both with stable and with Radioactive Ion Beams (RIB), like the ones foreseen for the SPES facility, where the Physics of Isospin can be studied., Comment: 13 pages, 19 figures - paper submitted to Eur. Phys. J. A
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- 2013
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49. Measurement of light charged particles in the decay channels of medium-mass excited compound nuclei
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Valdre', S., Barlini, S., Casini, G., Pasquali, G., Piantelli, S., Carboni, S., Cinausero, M., Gramegna, F., Marchi, T., Baiocco, G., Bardelli, L., Benzoni, G., Bini, M., Blasi, N., Bracco, A., Brambilla, S., Bruno, M., Camera, F., Corsi, A., Crespi, F., Agostino, M. D, Degerlier, M., Kravchuk, V. L., Leoni, S., Million, B., Montanari, D., Morelli, L., Nannini, A., Nicolini, R., Poggi, G., Vannini, G., Wieland, O., Bednarczyk, P., Ciemała, M., Dudek, J., Fornal, B., Kmiecik, M., Maj, A., Matejska-Minda, M., Mazurek, K., Meczynski, W., Myalski, S., Styczen, J., and Zieblinski, M.
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Nuclear Experiment - Abstract
The 48Ti on 40Ca reactions have been studied at 300 and 600 MeV focusing on the fusion-evaporation (FE) and fusion-fission (FF) exit channels. Energy spectra and multiplicities of the emitted light charged particles have been compared to Monte Carlo simulations based on the statistical model. Indeed, in this mass region (A about 100) models predict that shape transitions can occur at high spin values and relatively scarce data exist in the literature about coincidence measurements between evaporation residues and light charged particles. Signals of shape transitions can be found in the variations of the lineshape of high energy gamma rays emitted from the de-excitation of GDR states gated on different region of angular momenta. For this purpose it is important to keep under control the FE and FF processes, to regulate the statistical model parameters and to control the onset of possible preequilibrium emissions from 300 to 600 MeV bombarding energy., Comment: 4 pages, 3 figures, Contribution to conference proceedings of the 25th International Nuclear Physics Conference (INPC 2013) Journal-ref: 25th International Nuclear Physics Conference (INPC 2013), Firenze : Italy (2013)
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- 2013
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50. Probing the statistical decay and alpha-clustering effects in 12c+12c and 14n+10b reactions
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Morelli, Luca, Baiocco, G., Agostino, M. D, Bruno, M., Gulminelli, F., Cinausero, M., Degerlier, M., Fabris, D., Gramegna, F., Marchi, T., Barlini, S., Bini, M., Casini, G., Gelli, N., Lopez, A., Pasquali, G., Piantelli, S., and Valdre', S.
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Nuclear Experiment ,Nuclear Theory - Abstract
An experimental campaign has been undertaken at INFN Laboratori Nazionali di Legnaro, Italy, in order to progress in our understanding of the statistical properties of light nuclei at excitation energies above particle emission threshold, by measuring exclusive data from fusion-evaporation reactions. A first reaction 12C+12C at 7.9 AMeV beam energy has been measured, using the GARFIELD+Ring Counter experimental setup. Fusion-evaporation events have been exclusively selected. The comparison to a dedicated Hauser-Feshbach calculation allows us to give constraints on the nuclear level density at high excitation energy for light systems ranging from C up to Mg. Out-of-equilibrium emission has been evidenced and attributed both to entrance channel effects favoured by the cluster nature of reaction partners and, in more dissipative events, to the persistence of cluster correlations well above the 24Mg threshold for 6 alphas decay. The 24Mg compound nucleus has been studied with a new measurement 14N + 10B at 5.7 AMeV. The comparison between the two datasets would allow us to further constrain the level density of light nuclei. Deviations from a statistical behaviour can be analyzed to get information on nuclear clustering., Comment: 4 pages, 2 figures, Contribution to conference proceedings of the 25th International Nuclear Physics Conference (INPC 2013)
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- 2013
- Full Text
- View/download PDF
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