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Your search keyword '"Czerwinska-Kartowicz, I."' showing total 5 results
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5 results on '"Czerwinska-Kartowicz, I."'

1. [The effect of tobacco smoking on the human immune system]

Author

Derentowicz, P., Czerwinska-Kartowicz, I., Katarzyna Markiewicz, Wnuk, A., Rytwinski, K., Wawrzyniak, M., and Bulawa, E.

Subjects
Adult, Inflammation, Schools, Adolescent, Respiratory Tract Diseases, Smoking, Infant, Smoking Prevention, Pregnancy Complications, Cardiovascular Diseases, Pregnancy, Child, Preschool, Prenatal Exposure Delayed Effects, Humans, Female, Poland, Child, Health Education
Abstract

The influence of tobacco smoking in development of respiratory, cardiovascular diseases and impairment of foetal development is well documented. Recent studies have shown adverse effects of tobacco smoke on the immune system. Particular place of impact of tobacco smoke is BALT (bronchus-associated lymphoid tissue). Tobacco smoking increases the inflammatory processes and also has an immunosuppressive effect. It is very important in relation to more frequent youth and children diseases linked with the immune system. In school education programmes to prevent tobacco smoking carried out by the Institute of Mother and Child it is also very important to include this aspect.

2. [Nitric oxide (NO)--Nobel prize in medicine and physiology for 1998]

Author

Derentowicz, P., Katarzyna Markiewicz, Wawrzyniak, M., Czerwinska-Kartowicz, I., Bulawa, E., and Siwinska-Golebiowska, H.

Subjects
Animals, Humans, Infant, Gastrointestinal Motility, Nitric Oxide, Cardiovascular System, Nervous System, Shock, Septic, Nobel Prize, Signal Transduction
Abstract

On October 12, 1998. The Nobel Assembly announced the award of the Nobel Prize in Medicine and Physiology to pharmacologists Robert Furchgott, Louis Ignarro, and Ferid Murad. The Nobel Committee decided to award the prize for their discoveries concerning--nitric oxide as a signalling molecule in the cardiovascular system. Nitric oxide (NO) has a key importance for vascular tonus, acts as a signal molecule in the nervous system and plays an important function in the immunological system. Nitric oxide is a multifunction molecule which controls the blood pressure, modulates gastrointestinal motility. It is produced in abnormal level intensifies septic shock and destruction of nervous tissue. NO is important in different branches of medicine. For instance NO gas has been used to reduced high blood pressure in the lung of infants. Several unknown NO applications in medicine are waiting for discovery.

5. [Immunological confirmation of allergy in children with hypoimmunoglobulinemia].

Author

Siwinska-Golebiowska H, Czerwinska-Kartowicz I, Markiewicz K, Derentowicz P, and Golebiowska-Wawrzyniak M

Subjects
Adolescent, Allergens immunology, Antibody Specificity, Child, Diagnosis, Differential, Dysgammaglobulinemia blood, Female, Humans, Hypersensitivity, Immediate diagnosis, Immunoglobulin E blood, Lymphocyte Activation, Male, Poland, Risk Factors, Seroepidemiologic Studies, Dysgammaglobulinemia immunology, Hypersensitivity, Immediate immunology, Immunoglobulin E deficiency
Abstract

Unlabelled: The recognition of allergy in children with hypoimmunoglobulinemia is very difficult because they have very low level or even lack of specific IgE antibodies. Our research hypothesis was the possibility of detecting the specific sensitization of lymphocytes T to food allergens in children with hypoimmunoglobulinemia and with clinical symptoms of allergy., Material: 32 children actually treated in our Immunology Outpatients Department due to immunodeficiency connected with hypoimmunoglobulinemia and with clinical suspicion of allergy., Methods: IgE concentration in serum and IgE specific antibodies to food and pollens were examined by FEIA CAP-SYSTEM. Lymphocyte specific response to allergens (cow's milk, gluten) was examined by classical blast transformation test. Immunological profile of children was also evaluated., Results: In the group of 32 children we recognised: 20 children with predominantly antibody deficiencies (2 - agammaglobulinemia; 8 - CVID; 5 - selective immunoglobulins deficiency; 5 - hypoimmunoglobulinemia of infants) and 12 children who had combined immunodeficiency with hypoimmunoglobulinemia ( 3 - AT; 8 - Nijmegen S; 1 - Di George). The children had atopic dermatitis and clinical symptoms of allergy in respiratory and digestive tracts. Concentration of IgE in serum of children was very low, even < 2KU/L, Pediatric Phadiatop was negative, f2 and f79 were absent. Using lymphocytes transformation test (culture stimulated with cow's milk and gluten antigens) we detected sensitivity to cow's milk in 24 children and additionally in 4 of them sensitivity to gluten., Conclusions: 1) Laboratory difficulties in allergy diagnosis in children with hypoimmunoglobulinemia by evaluation of specific IgE concentration in serum may by caused by defect in biosynthesis of mentioned antibodies. 2) In children with hypoimmunoglobulinemia the lymphocyte blastic transformation test with specific allergens in cultures has a diagnostic value indicating lymphocytes specific response to allergens.

Published
2003

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