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This guideline applies to adult hospitalized non-critically ill patients with acute alcohol withdrawal in a nonintensive care setting. This guideline does not aid withdrawal of benzodiazepines or opioids. The objective to provide an evidence-based guideline for managing acute alcohol withdrawal, including screening and assessing patients with alcohol withdrawal syndrome (AWS); managing symptoms using a multimodal, symptom-triggered process; seeking consultation support; escalating care when appropriate; and providing long-term support for the patient., (© Regents of the University of Michigan.)