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4. Measurement depth of laser-induced tissue fluorescence with application to laser angioplasty

Author

Gmitro, Arthur F., Cutruzzola, Francis W., Stetz, Mark L., and Deckelbaum, Lawrence I.

Abstract

Laser-induced fluorescence spectroscopy can be used to discriminate between normal and atherosclerotic tissue and guide the delivery of high-power laser energy for laser angioplasty. The depth of tissue from which fluorescence is measured should closely match the depth of laser ablation and, from a practical standpoint, should be neither too small nor too large. This paper investigates the depth of the fluorescence signal. A simple mathematical model is presented. An experimental procedure for determining this depth is described. The results agree well with the model. The implications of the findings to the development of a practical fluorescence-guided laser angioplasty system are discussed.

Published
1988

5. “Medical Applications of Alexandrite User Systems”

Author

Kuper, Jerry W., primary, Langert, William E., additional, Baker, Martin C., additional, Barrett, J.J., additional, Deckelbaum, Lawrence I., additional, Stetz, Mark L., additional, Cutruzzola, Francis W., additional, and Steiger, Erwin, additional

Published
1987
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