15 results on '"Curto, Stefano"'
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2. Corrigendum: The silent epidemic of diabetic ketoacidosis at diagnosis of type 1 diabetes in children and adolescents in italy during the covid-19 pandemic in 2020
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Cherubini, Valentino, primary, Marino, Monica, additional, Scaramuzza, Andrea E., additional, Tiberi, Valentina, additional, Bobbio, Adriana, additional, Delvecchio, Maurizio, additional, Piccinno, Elvira, additional, Ortolani, Federica, additional, Innaurato, Stefania, additional, Felappi, Barbara, additional, Gallo, Francesco, additional, Ripoli, Carlo, additional, Ricciardi, Maria Rossella, additional, Pascarella, Filomena, additional, Stamati, Filomena A., additional, Citriniti, Felice, additional, Arnaldi, Claudia, additional, Monti, Sara, additional, Graziani, Vanna, additional, De Berardinis, Fiorella, additional, Giannini, Cosimo, additional, Chiarelli, Francesco, additional, Zampolli, Maria, additional, De Marco, Rosaria, additional, Bracciolini, Giulia Patrizia, additional, Grosso, Caterina, additional, De Donno, Valeria, additional, Piccini, Barbara, additional, Toni, Sonia, additional, Coccioli, Susanna, additional, Cardinale, Giuliana, additional, Bassi, Marta, additional, Minuto, Nicola, additional, D’Annunzio, Giuseppe, additional, Maffeis, Claudio, additional, Marigliano, Marco, additional, Zanfardino, Angela, additional, Iafusco, Dario, additional, Rollato, Assunta S., additional, Piscopo, Alessia, additional, Curto, Stefano, additional, Lombardo, Fortunato, additional, Bombaci, Bruno, additional, Sordelli, Silvia, additional, Mameli, Chiara, additional, Macedoni, Maddalena, additional, Rigamonti, Andrea, additional, Bonfanti, Riccardo, additional, Frontino, Giulio, additional, Predieri, Barbara, additional, Bruzzi, Patrizia, additional, Mozzillo, Enza, additional, Rosanio, Francesco, additional, Franzese, Adriana, additional, Piredda, Gavina, additional, Cardella, Francesca, additional, Iovane, Brunella, additional, Calcaterra, Valeria, additional, Berioli, Maria Giulia, additional, Lasagni, Anna, additional, Pampanini, Valentina, additional, Patera, Patrizia Ippolita, additional, Schiaffini, Riccardo, additional, Rutigliano, Irene, additional, Meloni, Gianfranco, additional, De Sanctis, Luisa, additional, Tinti, Davide, additional, Trada, Michela, additional, Guerraggio, Lucia Paola, additional, Franceschi, Roberto, additional, Cauvin, Vittoria, additional, Tornese, Gianluca, additional, Franco, Francesca, additional, Musolino, Gianluca, additional, Maltoni, Giulio, additional, Talarico, Valentina, additional, Iannilli, Antonio, additional, Lenzi, Lorenzo, additional, Matteoli, Maria Cristina, additional, Pozzi, Erica, additional, Moretti, Carlo, additional, Zucchini, Stefano, additional, Rabbone, Ivana, additional, and Gesuita, Rosaria, additional
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- 2022
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3. Very low birth weight newborn with diabetes mellitus due to pancreas agenesis managed with insulin pump reservoir filled with undiluted insulin: 16-month follow-up
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Zanfardino, Angela, primary, Piscopo, Alessia, additional, Curto, Stefano, additional, Schiaffini, Riccardo, additional, Rollato, Assunta S., additional, Testa, Veronica, additional, Miraglia del Giudice, Emanuele, additional, Barbetti, Fabrizio, additional, and Iafusco, Dario, additional
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- 2022
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4. The Silent Epidemic of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents in Italy During the COVID-19 Pandemic in 2020
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Cherubini, Valentino, primary, Marino, Monica, additional, Scaramuzza, Andrea E., additional, Tiberi, Valentina, additional, Bobbio, Adriana, additional, Delvecchio, Maurizio, additional, Piccinno, Elvira, additional, Ortolani, Federica, additional, Innaurato, Stefania, additional, Felappi, Barbara, additional, Gallo, Francesco, additional, Ripoli, Carlo, additional, Ricciardi, Maria Rossella, additional, Pascarella, Filomena, additional, Stamati, Filomena A., additional, Citriniti, Felice, additional, Arnaldi, Claudia, additional, Monti, Sara, additional, Graziani, Vanna, additional, De Berardinis, Fiorella, additional, Giannini, Cosimo, additional, Chiarelli, Francesco, additional, Zampolli, Maria, additional, De Marco, Rosaria, additional, Bracciolini, Giulia Patrizia, additional, Grosso, Caterina, additional, De Donno, Valeria, additional, Piccini, Barbara, additional, Toni, Sonia, additional, Coccioli, Susanna, additional, Cardinale, Giuliana, additional, Bassi, Marta, additional, Minuto, Nicola, additional, D’Annunzio, Giuseppe, additional, Maffeis, Claudio, additional, Marigliano, Marco, additional, Zanfardino, Angela, additional, Iafusco, Dario, additional, Rollato, Assunta S., additional, Piscopo, Alessia, additional, Curto, Stefano, additional, Lombardo, Fortunato, additional, Bombaci, Bruno, additional, Sordelli, Silvia, additional, Mameli, Chiara, additional, Macedoni, Maddalena, additional, Rigamonti, Andrea, additional, Bonfanti, Riccardo, additional, Frontino, Giulio, additional, Predieri, Barbara, additional, Bruzzi, Patrizia, additional, Mozzillo, Enza, additional, Rosanio, Francesco, additional, Franzese, Adriana, additional, Piredda, Gavina, additional, Cardella, Francesca, additional, Iovane, Brunella, additional, Calcaterra, Valeria, additional, Berioli, Maria Giulia, additional, Lasagni, Anna, additional, Pampanini, Valentina, additional, Patera, Patrizia Ippolita, additional, Schiaffini, Riccardo, additional, Rutigliano, Irene, additional, Meloni, Gianfranco, additional, De Sanctis, Luisa, additional, Tinti, Davide, additional, Trada, Michela, additional, Guerraggio, Lucia Paola, additional, Franceschi, Roberto, additional, Cauvin, Vittoria, additional, Tornese, Gianluca, additional, Franco, Francesca, additional, Musolino, Gianluca, additional, Maltoni, Giulio, additional, Talarico, Valentina, additional, Iannilli, Antonio, additional, Lenzi, Lorenzo, additional, Matteoli, Maria Cristina, additional, Pozzi, Erica, additional, Moretti, Carlo, additional, Zucchini, Stefano, additional, Rabbone, Ivana, additional, and Gesuita, Rosaria, additional
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- 2022
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5. Campylobacter jejuni bacteremia in Italian pediatric patients with acute lymphoblastic leukemia: Report of two cases
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Martora, Francesca, Pagliuca, Chiara, Della Pepa, Maria Elena, Della Rocca, Maria Teresa, Curto, Stefano, Iovene, Maria Rosaria, Vitiello, Mariateresa, Martora, Francesca, Pagliuca, Chiara, Della Pepa, Maria Elena, Della Rocca, Maria Teresa, Curto, Stefano, Iovene, Maria Rosaria, and Vitiello, Mariateresa
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Campylobacter jejuni ,acute lymphoblastic leukemia (ALL) ,Italy ,Campylobacter Infections ,Drug Resistance, Bacterial ,Humans ,Bacteremia ,Microbial Sensitivity Tests ,Precursor Cell Lymphoblastic Leukemia-Lymphoma ,bacterial infections and mycoses ,Child ,Anti-Bacterial Agents - Abstract
Infections caused by Campylobacter jejuni are rarely associated with extraintestinal complications. C. jejuni bacteremia is difficult to detect in patients with hematological malignancies undergoing chemotherapy where the choice of appropriate antibiotic treatment is extremely important. We report two cases of C. jejuni bacteremia in Italian pediatric patients affected by acute lymphoblastic leukemia (ALL). Agreeing with the most recent epidemiological data, both clinical isolates showed a typical phenotypic antimicrobial resistance patterns with combined resistance to ciprofloxacin and tetracycline. To our knowledge, this is the first report of C. jejuni isolation from the blood of ALL pediatric patients in Italy, and it provides important epidemiological information on this rare infection.
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- 2020
6. Metabolic Treatment of Wolfram Syndrome
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Iafusco, Dario, primary, Zanfardino, Angela, additional, Piscopo, Alessia, additional, Curto, Stefano, additional, Troncone, Alda, additional, Chianese, Antonietta, additional, Rollato, Assunta Serena, additional, Testa, Veronica, additional, Iafusco, Fernanda, additional, Maione, Giovanna, additional, Pennarella, Alessandro, additional, Boccabella, Lucia, additional, Ozen, Gulsum, additional, Palma, Pier Luigi, additional, Mazzaccara, Cristina, additional, Tinto, Nadia, additional, and Miraglia del Giudice, Emanuele, additional
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- 2022
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7. Sensor Augmented Pump Therapy is Safe and Effective in Very Low Birth Weight Newborns Affected by Neonatal Diabetes Mellitus, With Poor Subcutaneous Tissue: Replacement of the Insulin Pump Infusion Set on the Arm, a Video Case Report
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Zanfardino, Angela, primary, Carpentieri, Mauro, additional, Piscopo, Alessia, additional, Curto, Stefano, additional, Miraglia del Giudice, Emanuele, additional, Inverardi, Alessia, additional, Diplomatico, Mario, additional, Moschella, Sabino, additional, Spagnuolo, Ferdinando, additional, Caredda, Elisabetta, additional, Montaldo, Paolo, additional, and Iafusco, Dario, additional
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- 2021
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8. sj-pdf-1-dst-10.1177_19322968211043112 – Supplemental material for Sensor Augmented Pump Therapy is Safe and Effective in Very Low Birth Weight Newborns Affected by Neonatal Diabetes Mellitus, with Poor Subcutaneous Tissue: Replacement of the Insulin Pump Infusion Set on the Arm, a Video Case Report
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Zanfardino, Angela, Carpentieri, Mauro, Piscopo, Alessia, Curto, Stefano, Miraglia del Giudice, Emanuele, Inverardi, Alessia, Diplomatico, Mario, Moschella, Sabino, Spagnuolo, Ferdinando, Caredda, Elisabetta, Montaldo, Paolo, and Iafusco, Dario
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111708 Health and Community Services ,FOS: Clinical medicine ,111199 Nutrition and Dietetics not elsewhere classified ,Medicine ,FOS: Health sciences ,110306 Endocrinology - Abstract
Supplemental material, sj-pdf-1-dst-10.1177_19322968211043112 for Sensor Augmented Pump Therapy is Safe and Effective in Very Low Birth Weight Newborns Affected by Neonatal Diabetes Mellitus, with Poor Subcutaneous Tissue: Replacement of the Insulin Pump Infusion Set on the Arm, a Video Case Report by Angela Zanfardino, Mauro Carpentieri, Alessia Piscopo, Stefano Curto, Emanuele Miraglia del Giudice, Alessia Inverardi, Mario Diplomatico, Sabino Moschella, Ferdinando Spagnuolo, Elisabetta Caredda, Paolo Montaldo and Dario Iafusco in Journal of Diabetes Science and Technology
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- 2021
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9. High Dietary Salt Intake in Pediatric Patients with Type 1 Diabetes Mellitus Not Related to Overweight and Obesity
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Zanfardino, Angela, primary, Zanfardino, Angela, additional, Marzuillo, Pierluigi, additional, Sessa, Linda, additional, Rollato, Assunta S, additional, Testa, Veronica, additional, Gallo, Maria G, additional, Piscopo, Alessia, additional, Casaburo, Francesca, additional, Curto, Stefano, additional, Ozen, Gulsum, additional, del Giudice, Emanuele Miraglia, additional, Confetto, Santino, additional, and Iafusco, Dario, additional
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- 2020
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10. Demystifying the Pizza Bolus: The Effect of Dough Fermentation on Glycemic Response—A Sensor-Augmented Pump Intervention Trial in Children with Type 1 Diabetes Mellitus
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Zanfardino, Angela, primary, Confetto, Santino, additional, Curto, Stefano, additional, Cocca, Alessandra, additional, Rollato, Assunta Serena, additional, Zanfardino, Francesco, additional, Troise, Antonio Dario, additional, Testa, Veronica, additional, Bologna, Oriana, additional, Stanco, Michela, additional, Piscopo, Alessia, additional, Cohen, Ohad, additional, Miraglia del Giudice, Emanuele, additional, Vitaglione, Paola, additional, and Iafusco, Dario, additional
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- 2019
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11. Sovereign Wealth Funds in the Next Decade
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Curto, Stefano
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jel:G15 ,jel:G1 ,Sovereign wealth funds, SWF, recovery, economic recovery, financial crisis, investments, developing countries, South-South, savings, surplus ,Finance and Financial Sector Development - Debt Markets Banks and Banking Reform Private Sector Development - Emerging Markets Finance and Financial Sector Development - Currencies and Exchange Rates Finance and Financial Sector Development - Bankruptcy and Resolution of Financial Distress ,jel:F21 ,jel:E5 ,jel:E58 - Abstract
A prolonged and multispeed recovery period, its associated policy response, and the new global financial landscape might have important bearing on the size and allocation of sovereign wealth funds (SWFs) assets. SWFs could become a driving force in South-South flows, boosting global wealth by helping recycle large savings in surplus countries toward more productive investments. Whereas they indeed represent a new opportunity for developing countries, they also carry challenges for both home and host countries.
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- 2010
12. The Silent Epidemic of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents in Italy During the COVID-19 Pandemic in 2020
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Valentino Cherubini, Monica Marino, Andrea E. Scaramuzza, Valentina Tiberi, Adriana Bobbio, Maurizio Delvecchio, Elvira Piccinno, Federica Ortolani, Stefania Innaurato, Barbara Felappi, Francesco Gallo, Carlo Ripoli, Maria Rossella Ricciardi, Filomena Pascarella, Filomena A. Stamati, Felice Citriniti, Claudia Arnaldi, Sara Monti, Vanna Graziani, Fiorella De Berardinis, Cosimo Giannini, Francesco Chiarelli, Maria Zampolli, Rosaria De Marco, Giulia Patrizia Bracciolini, Caterina Grosso, Valeria De Donno, Barbara Piccini, Sonia Toni, Susanna Coccioli, Giuliana Cardinale, Marta Bassi, Nicola Minuto, Giuseppe D’Annunzio, Claudio Maffeis, Marco Marigliano, Angela Zanfardino, Dario Iafusco, Assunta S. Rollato, Alessia Piscopo, Stefano Curto, Fortunato Lombardo, Bruno Bombaci, Silvia Sordelli, Chiara Mameli, Maddalena Macedoni, Andrea Rigamonti, Riccardo Bonfanti, Giulio Frontino, Barbara Predieri, Patrizia Bruzzi, Enza Mozzillo, Francesco Rosanio, Adriana Franzese, Gavina Piredda, Francesca Cardella, Brunella Iovane, Valeria Calcaterra, Maria Giulia Berioli, Anna Lasagni, Valentina Pampanini, Patrizia Ippolita Patera, Riccardo Schiaffini, Irene Rutigliano, Gianfranco Meloni, Luisa De Sanctis, Davide Tinti, Michela Trada, Lucia Paola Guerraggio, Roberto Franceschi, Vittoria Cauvin, Gianluca Tornese, Francesca Franco, Gianluca Musolino, Giulio Maltoni, Valentina Talarico, Antonio Iannilli, Lorenzo Lenzi, Maria Cristina Matteoli, Erica Pozzi, Carlo Moretti, Stefano Zucchini, Ivana Rabbone, Rosaria Gesuita, Cherubini, Valentino, Marino, Monica, Scaramuzza, Andrea E, Tiberi, Valentina, Bobbio, Adriana, Delvecchio, Maurizio, Piccinno, Elvira, Ortolani, Federica, Innaurato, Stefania, Felappi, Barbara, Gallo, Francesco, Ripoli, Carlo, Ricciardi, Maria Rossella, Pascarella, Filomena, Stamati, Filomena A, Citriniti, Felice, Arnaldi, Claudia, Monti, Sara, Graziani, Vanna, De Berardinis, Fiorella, Giannini, Cosimo, Chiarelli, Francesco, Zampolli, Maria, De Marco, Rosaria, Bracciolini, Giulia Patrizia, Grosso, Caterina, De Donno, Valeria, Piccini, Barbara, Toni, Sonia, Coccioli, Susanna, Cardinale, Giuliana, Bassi, Marta, Minuto, Nicola, D'Annunzio, Giuseppe, Maffeis, Claudio, Marigliano, Marco, Zanfardino, Angela, Iafusco, Dario, Rollato, Assunta S, Piscopo, Alessia, Curto, Stefano, Lombardo, Fortunato, Bombaci, Bruno, Sordelli, Silvia, Mameli, Chiara, Macedoni, Maddalena, Rigamonti, Andrea, Bonfanti, Riccardo, Frontino, Giulio, Predieri, Barbara, Bruzzi, Patrizia, Mozzillo, Enza, Rosanio, Francesco, Franzese, Adriana, Piredda, Gavina, Cardella, Francesca, Iovane, Brunella, Calcaterra, Valeria, Berioli, Maria Giulia, Lasagni, Anna, Pampanini, Valentina, Patera, Patrizia Ippolita, Schiaffini, Riccardo, Rutigliano, Irene, Meloni, Gianfranco, De Sanctis, Luisa, Tinti, Davide, Trada, Michela, Guerraggio, Lucia Paola, Franceschi, Roberto, Cauvin, Vittoria, Tornese, Gianluca, Franco, Francesca, Musolino, Gianluca, Maltoni, Giulio, Talarico, Valentina, Iannilli, Antonio, Lenzi, Lorenzo, Matteoli, Maria Cristina, Pozzi, Erica, Moretti, Carlo, Zucchini, Stefano, Rabbone, Ivana, and Gesuita, Rosaria
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COVID - 19 ,Adolescent ,type 1 diabetes ,Endocrinology, Diabetes and Metabolism ,Longitudinal Studie ,Diabetic Ketoacidosis ,socioeconomic status ,DKA ,Diabetes Mellitus ,Humans ,Longitudinal Studies ,Child ,Pandemics ,Settore MED/38 - Pediatria Generale e Specialistica ,Pandemic ,type 1 diabete ,Incidence ,COVID-19 ,diabetes onset ,Communicable Disease Control ,Italy ,Diabetes Mellitus, Type 1 ,socioeconomic statu ,Human ,Type 1 - Abstract
Aim/HypothesisTo compare the frequency of diabetic ketoacidosis (DKA) at diagnosis of type 1 diabetes in Italy during the COVID-19 pandemic in 2020 with the frequency of DKA during 2017-2019.MethodsForty-seven pediatric diabetes centers caring for >90% of young people with diabetes in Italy recruited 4,237 newly diagnosed children with type 1 diabetes between 2017 and 2020 in a longitudinal study. Four subperiods in 2020 were defined based on government-imposed containment measures for COVID-19, and the frequencies of DKA and severe DKA compared with the same periods in 2017-2019.ResultsOverall, the frequency of DKA increased from 35.7% (95%CI, 33.5-36.9) in 2017-2019 to 39.6% (95%CI, 36.7-42.4) in 2020 (p=0.008), while the frequency of severe DKA increased from 10.4% in 2017-2019 (95%CI, 9.4-11.5) to 14.2% in 2020 (95%CI, 12.3-16.4, pConclusions/InterpretationThere was an increase in the frequency of DKA and severe DKA in children newly diagnosed with type 1 diabetes during the COVID-19 pandemic in 2020, with no apparent association with the severity of COVID-19 infection severity or containment measures. There has been a silent outbreak of DKA in children during the pandemic, and preventive action is required to prevent this phenomenon in the event of further generalized lockdowns or future outbreaks.
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- 2022
13. Metabolic Treatment of Wolfram Syndrome
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Dario Iafusco, Angela Zanfardino, Alessia Piscopo, Stefano Curto, Alda Troncone, Antonietta Chianese, Assunta Serena Rollato, Veronica Testa, Fernanda Iafusco, Giovanna Maione, Alessandro Pennarella, Lucia Boccabella, Gulsum Ozen, Pier Luigi Palma, Cristina Mazzaccara, Nadia Tinto, Emanuele Miraglia del Giudice, Iafusco, Dario, Zanfardino, Angela, Piscopo, Alessia, Curto, Stefano, Troncone, Alda, Chianese, Antonietta, Rollato, Assunta Serena, Testa, Veronica, Iafusco, Fernanda, Maione, Giovanna, Pennarella, Alessandro, Boccabella, Lucia, Ozen, Gulsum, Palma, Pier Luigi, Mazzaccara, Cristina, Tinto, Nadia, Miraglia Del Giudice, Emanuele, Iafusco, D., Zanfardino, A., Piscopo, A., Curto, S., Troncone, A., Chianese, A., Rollato, A. S., Testa, V., Iafusco, F., Maione, G., Pennarella, A., Boccabella, L., Ozen, G., Palma, P. L., Mazzaccara, C., Tinto, N., and Miraglia Del Giudice, E.
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Adult ,Young Adult ,Adolescent ,diabetes mellitu ,Health, Toxicology and Mutagenesis ,insulin therapy ,Public Health, Environmental and Occupational Health ,Quality of Life ,Humans ,Neurodegenerative Diseases ,Wolfram Syndrome ,Child - Abstract
Wolfram Syndrome (WS) is a very rare genetic disorder characterized by several symptoms that occur from childhood to adulthood. Usually, the first clinical sign is non-autoimmune diabetes even if other clinical features (optic subatrophy, neurosensorial deafness, diabetes insipidus) may be present in an early state and may be diagnosed after diabetes’ onset. Prognosis is poor, and the death occurs at the median age of 39 years as a consequence of progressive respiratory impairment, secondary to brain atrophy and neurological failure. The aim of this paper is the description of the metabolic treatment of the WS. We reported the experience of long treatment in patients with this syndrome diagnosed in pediatric age and followed also in adult age. It is known that there is a correlation between metabolic control of diabetes, the onset of other associated symptoms, and the progression of the neurodegenerative alterations. Therefore, a multidisciplinary approach is necessary in order to prevent, treat and carefully monitor all the comorbidities that may occur. An extensive understanding of WS from pathophysiology to novel possible therapy is fundamental and further studies are needed to better manage this devastating disease and to guarantee to patients a better quality of life and a longer life expectancy.
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- 2021
14. Demystifying the Pizza Bolus: The Effect of Dough Fermentation on Glycemic Response-A Sensor-Augmented Pump Intervention Trial in Children with Type 1 Diabetes Mellitus
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Antonio Dario Troise, Francesco Zanfardino, Michela Stanco, Emanuele Miraglia del Giudice, Alessandra Cocca, Assunta S Rollato, Paola Vitaglione, Stefano Curto, Veronica Testa, Angela Zanfardino, Ohad Cohen, Dario Iafusco, Oriana Bologna, Santino Confetto, Alessia Piscopo, Zanfardino, Angela, Confetto, Santino, Curto, Stefano, Cocca, Alessandra, Rollato, Assunta Serena, Zanfardino, Francesco, Troise, Antonio Dario, Testa, Veronica, Bologna, Oriana, Stanco, Michela, Piscopo, Alessia, Cohen, Ohad, Miraglia Del Giudice, Emanuele, Vitaglione, Paola, and Iafusco, Dario
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Dough fermentation ,Blood Glucose ,Male ,endocrine system diseases ,Adolescent ,Endocrinology, Diabetes and Metabolism ,medicine.medical_treatment ,Continuous subcutaneous insulin infusion ,030209 endocrinology & metabolism ,Hypoglycemia ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Bolus (medicine) ,Diabetes mellitus ,Medicine ,Humans ,Hypoglycemic Agents ,Insulin ,030212 general & internal medicine ,Intervention trial ,Child ,Meals ,Glycemic ,Type 1 diabetes ,business.industry ,digestive, oral, and skin physiology ,nutritional and metabolic diseases ,medicine.disease ,Postprandial Period ,Diet ,Medical Laboratory Technology ,Diabetes Mellitus, Type 1 ,Food ,Anesthesia ,Child, Preschool ,Hyperglycemia ,Fermentation ,Pizza ,Female ,business ,hormones, hormone substitutes, and hormone antagonists - Abstract
Background: Glycemia following pizza consumption is typically managed with a dual-wave insulin bolus. This study evaluated the effect of a simple bolus on glycemia following consumption of traditionally prepared pizzas with long (24 h) or short (8 h) dough fermentation periods. Research Design and Methods: On two separate evenings, children with type 1 diabetes (n = 38) receiving sensor-integrated pump therapy consumed traditionally prepared pizza with either short (pizza A) or long (pizza B) dough fermentation, and blood glucose was monitored over 11 h. A simple insulin bolus was administered 15 min preprandially. The carbohydrate and amino acid contents of the two types of pizza were analyzed by liquid chromatography and high-resolution mass spectrometry (LC-HRMS). Results: The mean (±standard deviation) time in range 3.9-10.0 mmol/L was 73.2% ± 23.2%, and 50.8% ± 26.7% of glucose measurements were within the range 3.9-7.8 mmol/L. However, during the 2 h after bolus administration, the mean time in range 3.9-7.8 mmol/L was significantly greater with pizza B than with pizza A (73.3% ± 31.5% vs. 51.8% ± 37.4%, respectively, P = 0.009), and the time in hyperglycemia (>10 mmol/L) was significantly shorter (mean percentage 6.1% ± 19.0% vs. 17.7% ± 29.8%, respectively, P = 0.019). LC-HRMS analysis showed that long fermentation was associated with a lower carbohydrate content in the pizza, and a higher amino acid content. Conclusions: Glycemia following consumption of traditionally prepared pizza can be managed using a simple bolus 15 min before eating. Glycemic control can be further improved by increasing the dough fermentation time. Study registration: NCT03748251, Clinicaltrials.gov.
- Published
- 2019
15. Sensor Augmented Pump Therapy is Safe and Effective in Very Low Birth Weight Newborns Affected by Neonatal Diabetes Mellitus, With Poor Subcutaneous Tissue: Replacement of the Insulin Pump Infusion Set on the Arm, a Video Case Report.
- Author
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Zanfardino A, Carpentieri M, Piscopo A, Curto S, Miraglia Del Giudice E, Inverardi A, Diplomatico M, Moschella S, Spagnuolo F, Caredda E, Montaldo P, and Iafusco D
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- Blood Glucose, Humans, Hypoglycemic Agents therapeutic use, Infant, Newborn, Infant, Very Low Birth Weight, Insulin therapeutic use, Insulin Infusion Systems, Arm, Diabetes Mellitus, Type 1 drug therapy
- Published
- 2022
- Full Text
- View/download PDF
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