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156 results on '"Cuneo, Alessandro"'

1. Impact of Access Site on Periprocedural Bleeding and Cerebral and Coronary Events in High-Bleeding-Risk Percutaneous Coronary Intervention: Findings from the RIVA-PCI Trial

Author

Borlich, Martin, Zeymer, Uwe, Wienbergen, Harm, Hobbach, Hans-Peter, Cuneo, Alessandro, Bekeredjian, Raffi, Ritter, Oliver, Hailer, Birgit, Hertting, Klaus, Hennersdorf, Marcus, Scholtz, Werner, Lanzer, Peter, Mudra, Harald, Schwefer, Markus, Schwimmbeck, Peter-Lothar, Liebetrau, Christoph, Thiele, Holger, Claas, Christoph, Riemer, Thomas, Zahn, Ralf, Iden, Leon, Richardt, Gert, and Toelg, Ralph

Published
2024
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2. EduPort: An Intelligent Learning System Based on Deep Learning - A Preliminary Evaluation

Author

Cuneo, Alessandro, D’Urso, Stefano, Sciarrone, Filippo, Temperini, Marco, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, van Leeuwen, Jan, Series Editor, Hutchison, David, Editorial Board Member, Kanade, Takeo, Editorial Board Member, Kittler, Josef, Editorial Board Member, Kleinberg, Jon M., Editorial Board Member, Kobsa, Alfred, Series Editor, Mattern, Friedemann, Editorial Board Member, Mitchell, John C., Editorial Board Member, Naor, Moni, Editorial Board Member, Nierstrasz, Oscar, Series Editor, Pandu Rangan, C., Editorial Board Member, Sudan, Madhu, Series Editor, Terzopoulos, Demetri, Editorial Board Member, Tygar, Doug, Editorial Board Member, Weikum, Gerhard, Series Editor, Vardi, Moshe Y, Series Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Kubincová, Zuzana, editor, Hao, Tianyong, editor, Capuano, Nicola, editor, Temperini, Marco, editor, Ge, Shili, editor, Mu, Yuanyuan, editor, Fantozzi, Paolo, editor, and Yang, Jing, editor

Published
2024
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3. Current status of antithrombotic therapy and in-hospital outcomes in patients with atrial fibrillation undergoing percutaneous coronary intervention in Germany

Author

Zeymer, Uwe, Toelg, Ralph, Wienbergen, Harm, Hobbach, Hans-Peter, Cuneo, Alessandro, Bekeredjian, Raffi, Ritter, Oliver, Hailer, Birgit, Hertting, Klaus, Hennersdorf, Marcus, Scholtz, Werner, Lanzer, Peter, Mudra, Harald, Schwefer, Markus, Schwimmbeck, Peter-Lothar, Liebetrau, Christoph, Thiele, Holger, Claas, Christoph, Riemer, Thomas, and Zahn, Ralf

Published
2023
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4. Rivaroxaban in Patients With Atrial Fibrillation Who Underwent Percutaneous Coronary Intervention in Clinical Practice

Author

Zeymer, Uwe, Toelg, Ralph, Wienbergen, Harm, Hobbach, Hans-Peter, Cuneo, Alessandro, Bekeredjian, Raffi, Ritter, Oliver, Hailer, Birgit, Hertting, Klaus, Hennersdorf, Marcus, Scholtz, Werner, Lanzer, Peter, Mudra, Harald, Schwefer, Markus, Schwimmbeck, Peter-Lothar, Liebetrau, Christoph, Thiele, Holger, Claas, Christoph, Riemer, Thomas, and Zahn, Ralf

Published
2023
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6. Ethnic comparison in takotsubo syndrome: novel insights from the International Takotsubo Registry

Author

Imori, Yoichi, Kato, Ken, Cammann, Victoria L., Szawan, Konrad A., Wischnewsky, Manfred, Dreiding, Sara, Würdinger, Michael, Schönberger, Maximilian, Petkova, Vanya, Niederseer, David, Levinson, Rena A., Di Vece, Davide, Gili, Sebastiano, Seifert, Burkhardt, Wakita, Masaki, Suzuki, Noriko, Citro, Rodolfo, Bossone, Eduardo, Heiner, Susanne, Knorr, Maike, Jansen, Thomas, Münzel, Thomas, D’Ascenzo, Fabrizio, Franke, Jennifer, Sorici-Barb, Ioana, Katus, Hugo A., Sarcon, Annahita, Shinbane, Jerold, Napp, L. Christian, Bauersachs, Johann, Jaguszewski, Milosz, Shiomura, Reiko, Nakamura, Shunichi, Takano, Hitoshi, Noutsias, Michel, Burgdorf, Christof, Ishibashi, Iwao, Himi, Toshiharu, Koenig, Wolfgang, Schunkert, Heribert, Thiele, Holger, Kherad, Behrouz, Tschöpe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Mizuno, Shingo, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuß, Gerd, Karakas, Mahir, Mochizuki, Hiroki, Pott, Alexander, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian, Isogai, Toshiaki, Kimura, Akihisa, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Tomita, Yasuhiro, Budnik, Monika, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Murakami, Tsutomu, Ikari, Yuji, Empen, Klaus, Beug, Daniel, Felix, Stephan B., Delmas, Clément, Lairez, Olivier, Yamaguchi, Tetsuo, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Horowitz, John D., Kozel, Martin, Tousek, Petr, Widimský, Petr, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Neuhaus, Michael, Meyer, Philippe, Arroja, Jose David, Chan, Christina, Bridgman, Paul, Galuszka, Jan, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Pinto, Fausto J., Hauck, Christian, Maier, Lars S., Liu, Kan, Di Mario, Carlo, Paolini, Carla, Bilato, Claudio, Bianco, Matteo, Jörg, Lucas, Rickli, Hans, Winchester, David E., Ukena, Christian, Böhm, Michael, Bax, Jeroen J., Prasad, Abhiram, Rihal, Charanjit S., Saito, Shigeru, Kobayashi, Yoshio, Lüscher, Thomas F., Ruschitzka, Frank, Shimizu, Wataru, Ghadri, Jelena R., and Templin, Christian

Published
2022
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7. Cardiac biomarkers for diagnosing Takotsubo syndrome

Author

Schweiger, Victor, primary, Di Vece, Davide, additional, Cammann, Victoria L, additional, Koleva, Iva, additional, Würdinger, Michael, additional, Gilhofer, Thomas, additional, Rajman, Katja, additional, Szawan, Konrad A, additional, Niederseer, David, additional, Citro, Rodolfo, additional, Vecchione, Carmine, additional, Bossone, Eduardo, additional, Gili, Sebastiano, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Miłosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Jansen, Thomas, additional, D’Ascenzo, Fabrizio, additional, Bruno, Francesco, additional, De Filippo, Ovidio, additional, Stefanini, Giulio, additional, Campo, Gianluca, additional, Wanha, Wojciech, additional, Roubin, Sergio Raposeiras, additional, Dichtl, Wolfgang, additional, von Lewinski, Dirk, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Roffi, Marco, additional, Banning, Adrian, additional, Wolfrum, Mathias, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A, additional, Vasankari, Tuija, additional, Airaksinen, K E Juhani, additional, Napp, L Christian, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Poledniková, Karolina, additional, Toušek, Petr, additional, Winchester, David E, additional, Massoomi, Michael, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho-Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Kobayashi, Yoshio, additional, Kato, Ken, additional, Ishibashi, Iwao, additional, Himi, Toshiharu, additional, Din, Jehangir, additional, Al-Shammari, Ali, additional, Prasad, Abhiram, additional, Rihal, Charanjit S, additional, Liu, Kan, additional, Schulze, P Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H, additional, Böhm, Michael, additional, Maier, Lars S, additional, Pinto, Fausto J, additional, Widimský, Petr, additional, Felix, Stephan B, additional, Braun-Dullaeus, Ruediger C, additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M, additional, Schunkert, Heribert, additional, Budnik, Monika, additional, Opolski, Grzegorz, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Horowitz, John D, additional, Di Mario, Carlo, additional, Kong, William, additional, Dalakoti, Mayank, additional, Imori, Yoichi, additional, Münzel, Thomas, additional, Bax, Jeroen J, additional, Lüscher, Thomas F, additional, Crea, Filippo, additional, Ruschitzka, Frank, additional, Ghadri, Jelena R, additional, and Templin, Christian, additional

Published
2024
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8. Impact of Access Site on Periprocedural Bleeding and Cerebral and Coronary Events in High-Bleeding-Risk Percutaneous Coronary Intervention: Findings from the RIVA-PCI Trial

Author

Borlich, Martin, primary, Zeymer, Uwe, additional, Wienbergen, Harm, additional, Hobbach, Hans-Peter, additional, Cuneo, Alessandro, additional, Bekeredjian, Raffi, additional, Ritter, Oliver, additional, Hailer, Birgit, additional, Hertting, Klaus, additional, Hennersdorf, Marcus, additional, Scholtz, Werner, additional, Lanzer, Peter, additional, Mudra, Harald, additional, Schwefer, Markus, additional, Schwimmbeck, Peter-Lothar, additional, Liebetrau, Christoph, additional, Thiele, Holger, additional, Claas, Christoph, additional, Riemer, Thomas, additional, Zahn, Ralf, additional, Iden, Leon, additional, Richardt, Gert, additional, and Toelg, Ralph, additional

Published
2023
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10. Machine learning‐based prediction of in‐hospital death for patients with takotsubo syndrome: The InterTAK‐ML model

Author

De Filippo, Ovidio, primary, Cammann, Victoria L., additional, Pancotti, Corrado, additional, Di Vece, Davide, additional, Silverio, Angelo, additional, Schweiger, Victor, additional, Niederseer, David, additional, Szawan, Konrad A., additional, Würdinger, Michael, additional, Koleva, Iva, additional, Dusi, Veronica, additional, Bellino, Michele, additional, Vecchione, Carmine, additional, Parodi, Guido, additional, Bossone, Eduardo, additional, Gili, Sebastiano, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Miłosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Jansen, Thomas, additional, Dichtl, Wolfgang, additional, von Lewinski, Dirk, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Roffi, Marco, additional, Banning, Adrian, additional, Wolfrum, Mathias, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Napp, L. Christian, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Poledniková, Karolina, additional, Toušek, Petr, additional, Winchester, David E., additional, Massoomi, Michael, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho‐Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Kobayashi, Yoshio, additional, Kato, Ken, additional, Ishibashi, Iwao, additional, Himi, Toshiharu, additional, Din, Jehangir, additional, Al‐Shammari, Ali, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H., additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Felix, Stephan B., additional, Braun‐Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Budnik, Monika, additional, Opolski, Grzegorz, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Bruno, Francesco, additional, Kong, William, additional, Dalakoti, Mayank, additional, Imori, Yoichi, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Lüscher, Thomas F., additional, Bax, Jeroen J., additional, Ruschitzka, Frank, additional, De Ferrari, Gaetano Maria, additional, Fariselli, Piero, additional, Ghadri, Jelena R., additional, Citro, Rodolfo, additional, D'Ascenzo, Fabrizio, additional, and Templin, Christian, additional

Published
2023
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11. Impact of Access Site on Periprocedural Bleeding, Cerebrovascular, and Coronary Events in High-Bleeding-Risk Percutaneous Coronary Intervention: Findings from the RIVA-PCI Trial

Author

Borlich, Martin, primary, Zeymer, Uwe, additional, Wienbergen, Harm, additional, Hobbach, Hans-Peter, additional, Cuneo, Alessandro, additional, Bekeredjian, Raffi, additional, Ritter, Oliver, additional, Hailer, Birgit, additional, Hertting, Klaus, additional, Hennersdorf, Marcus, additional, Scholtz, Werner, additional, Lanzer, Peter, additional, Mudra, Harald, additional, Schwefer, Markus, additional, Schwimmbeck, Peter-Lothar, additional, Liebetrau, Christoph, additional, Thiele, Holger, additional, Claas, Christoph, additional, Riemer, Thomas, additional, Zahn, Ralf, additional, Iden, Leon, additional, Richardt, Gert, additional, and Toelg, Ralph, additional

Published
2023
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12. Intraventricular Thrombus Formation and Embolism in Takotsubo Syndrome: Insights From the International Takotsubo Registry

Author

Ding, Katharina J., Cammann, Victoria L., Szawan, Konrad A., Stähli, Barbara E., Wischnewsky, Manfred, Di Vece, Davide, Citro, Rodolfo, Jaguszewski, Milosz, Seifert, Burkhardt, Sarcon, Annahita, Knorr, Maike, Heiner, Susanne, Gili, Sebastiano, D’Ascenzo, Fabrizio, Neuhaus, Michael, Napp, L. Christian, Franke, Jennifer, Noutsias, Michel, Burgdorf, Christof, Koenig, Wolfgang, Kherad, Behrouz, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Pott, Alexander, Meyer, Philippe, Arroja, Jose D., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K.E. Juhani, Paolini, Carla, Bilato, Claudio, Carrilho-Ferreira, Pedro, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Chan, Christina, Bridgman, Paul, Delmas, Clément, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Kozel, Martin, Tousek, Petr, Widimský, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Horowitz, John D., Di Mario, Carlo, Prasad, Abhiram, Rihal, Charanjit S., Pinto, Fausto J., Crea, Filippo, Borggrefe, Martin, Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Bauersachs, Johann, Katus, Hugo A., Hasenfuß, Gerd, Tschöpe, Carsten, Pieske, Burkert M., Thiele, Holger, Schunkert, Heribert, Böhm, Michael, Felix, Stephan B., Münzel, Thomas, Bax, Jeroen J., Lüscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Bossone, Eduardo, and Templin, Christian

Published
2020
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13. Cangrelor in patients with percutaneous coronary intervention for acute myocardial infarction after cardiac arrest and/or with cardiogenic shock

Author

Zeymer, Uwe, primary, Lober, Christiane, additional, Richter, Stephan, additional, Olivier, Christoph B, additional, Huber, Kurt, additional, Haring, Bernhard, additional, Schwimmbeck, Peter, additional, Andrassy, Martin, additional, Akin, Ibrahim, additional, Cuneo, Alessandro, additional, Desch, Steffen, additional, Thiele, Holger, additional, and Geisler, Tobias, additional

Published
2023
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14. Outcomes Associated With Cardiogenic Shock in Takotsubo Syndrome: Results From the International Takotsubo Registry

Author

Di Vece, Davide, Citro, Rodolfo, Cammann, Victoria L., Kato, Ken, Gili, Sebastiano, Szawan, Konrad A., Micek, Jozef, Jurisic, Stjepan, Ding, Katharina J., Bacchi, Beatrice, Schwyzer, Moritz, Candreva, Alessandro, Bossone, Eduardo, D’Ascenzo, Fabrizio, Sarcon, Annahita, Franke, Jennifer, Napp, L. Christian, Jaguszewski, Milosz, Noutsias, Michel, Münzel, Thomas, Knorr, Maike, Heiner, Susanne, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Tschöpe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuβ, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K.E. Juhani, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Empen, Klaus, Felix, Stephan B., Delmas, Clément, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Horowitz, John, Kozel, Martin, Tousek, Petr, Widimský, Petr, Winchester, David E., Ukena, Christian, Di Mario, Carlo, Prasad, Abhiram, Böhm, Michael, Bax, Jeroen J., Lüscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., and Templin, Christian

Published
2019
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15. Supplement to: Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy

Author

Templin, Christian, Ghadri, Jelena R., Diekmann, Johanna, Napp, Christian L., Bataiosu, Dana R., Jaguszewski, Milosz, Cammann, Victoria L., Sarcon, Annahita, Geyer, Verena, Neumann, Catharina A., Seifert, Burkhardt, Hellermann, Jens, Schwyzer, Moritz, Eisenhardt, Katharina, Jenewein, Josef, Franke, Jennifer, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Moeller, Christian, Thiele, Holger, Bauersachs, Johann, Tschöpe, Carsten, Schultheiss, Heinz-Peter, Laney, Charles A., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Ukena, Christian, Böhm, Michael, Erbel, Raimund, Cuneo, Alessandro, Kuck, Karl-Heinz, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Cuculi, Florim, Banning, Adrian, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, Juhani K.E., Fijalkowski, Marcin, Rynkiewicz, Andrzej, Pawlak, Maciej, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Franz, Wolfgang M., Empen, Klaus, Felix, Stephan B., Delmas, Clément, Lairez, Olivier, Erne, Paul, Bax, Jeroen J., Ford, Ian, Ruschitzka, Frank, Prasad, Abhiram, and Lüscher, Thomas F.

Published
2015

16. Current status of antithrombotic therapy and in-hospital outcomes in patients with atrial fibrillation undergoing percutaneous coronary intervention in Germany

Author

Zeymer, Uwe, primary, Toelg, Ralph, additional, Wienbergen, Harm, additional, Hobbach, Hans-Peter, additional, Cuneo, Alessandro, additional, Bekeredjian, Raffi, additional, Ritter, Oliver, additional, Hailer, Birgit, additional, Hertting, Klaus, additional, Hennersdorf, Marcus, additional, Scholtz, Werner, additional, Lanzer, Peter, additional, Mudra, Harald, additional, Schwefer, Markus, additional, Schwimmbeck, Peter-Lothar, additional, Liebetrau, Christoph, additional, Thiele, Holger, additional, Claas, Christoph, additional, Riemer, Thomas, additional, and Zahn, Ralf, additional

Published
2022
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17. Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy

Author

Templin, Christian, Ghadri, Jelena R., Diekmann, Johanna, Napp, Christian L., Bataiosu, Dana R., Jaguszewski, Milosz, Cammann, Victoria L., Sarcon, Annahita, Geyer, Verena, Neumann, Catharina A., Seifert, Burkhardt, Hellermann, Jens, Schwyzer, Moritz, Eisenhardt, Katharina, Jenewein, Josef, Franke, Jennifer, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Moeller, Christian, Thiele, Holger, Bauersachs, Johann, Tschöpe, Carsten, Schultheiss, Heinz-Peter, Laney, Charles A., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Ukena, Christian, Böhm, Michael, Erbel, Raimund, Cuneo, Alessandro, Kuck, Karl-Heinz, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Cuculi, Florim, Banning, Adrian, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, Juhani K.E., Fijalkowski, Marcin, Rynkiewicz, Andrzej, Pawlak, Maciej, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Franz, Wolfgang M., Empen, Klaus, Felix, Stephan B., Delmas, Clément, Lairez, Olivier, Erne, Paul, Bax, Jeroen J., Ford, Ian, Ruschitzka, Frank, Prasad, Abhiram, and Lüscher, Thomas F.

Published
2015
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18. Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry

Author

El-Battrawy, Ibrahim, Cammann, Victoria L, Kato, Ken, Szawan, Konrad A, Di Vece, Davide, Rossi, Aurelio, Wischnewsky, Manfred, Hermes-Laufer, Julia, Gili, Sebastiano, Citro, Rodolfo, Bossone, Eduardo, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Milosz, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, D'Ascenzo, Fabrizio, Dichtl, Wolfgang, Burgdorf, Christof, Kherad, Behrouz, Tschöpe, Carsten, Sarcon, Annahita, Shinbane, Jerold, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, et al, and University of Zurich

Subjects
10209 Clinic for Cardiology, 610 Medicine & health, 2705 Cardiology and Cardiovascular Medicine
Published
2021

24. Clinical correlates and prognostic impact of neurologic disorders in Takotsubo syndrome

Author

Cammann, Victoria L, Scheitz, Jan F., Ghadri, Jelena R, Budnik, Monika, Opolski, Grzegorz, Borggrefe, Martin, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A, Horowitz, John D, Di Mario, Carlo, Münzel, Thomas, Crea, Filippo, Consortium, InterTAK, Bax, Jeroen J, Scherff, Frank, Niederseer, David, Lüscher, Thomas F, Citro, Rodolfo, Vecchione, Carmine, Bossone, Eduardo, Gili, Sebastiano, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Miłosz, von Rennenberg, Regina, Noutsias, Michel, Knorr, Maike, Jansen, Thomas, D'Ascenzo, Fabrizio, Dichtl, Wolfgang, Burgdorf, Christof, Kherad, Behrouz, Tschöpe, Carsten, Sarcon, Annahita, Shinbane, Jerold, Jäncke, Lutz, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Koenig, Wolfgang, Pott, Alexander, Meyer, Philippe, Roffi, Marco, Nolte, Christian, Banning, Adrian, Wolfrum, Mathias, Cuculi, Florim, Kobza, Richard, Fischer, Thomas, Vasankari, Tuija, Airaksinen, K E Juhani, Napp, L Christian, Dworakowski, Rafal, MacCarthy, Philip, Szawan, Konrad A, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clément, Lairez, Olivier, Gilyarova, Ekaterina, Shilova, Alexandra, Stengl, Helena, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Poledniková, Karolina, Toušek, Petr, Winchester, David E, Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Würdinger, Michael, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Kobayashi, Yoshio, Kato, Ken, Shoji, Toshihiro, Ishibashi, Iwao, Takahara, Masayuki, Himi, Toshiharu, Din, Jehangir, Endres, Matthias, Al-Shammari, Ali, Prasad, Abhiram, Rihal, Charanjit S, Liu, Kan, Schulze, Peter, Bianco, Matteo, Jörg, Lucas, Rickli, Hans, Pestana, Gonçalo, Nguyen, Thanh H, Templin, Christian, Böhm, Michael, Maier, Lars S, Pinto, Fausto J, Widimský, Petr, Felix, Stephan B, Braun-Dullaeus, Ruediger C, Rottbauer, Wolfgang, Hasenfuß, Gerd, Pieske, Burkert M, Schunkert, Heribert, University of Zurich, and Repositório da Universidade de Lisboa

Subjects
Adult, Male, Science, Cardiology, heart disease risk factors, complications [Seizures], Article, Seizures, Takotsubo Cardiomyopathy, diagnosis [Takotsubo Cardiomyopathy], Humans, Hospital Mortality, Registries, humans, Ischemic Stroke, Aged, Aged, 80 and over, hospital mortality, mortality [Takotsubo Cardiomyopathy], Multidisciplinary, complications [Intracranial Hemorrhages], 10093 Institute of Psychology, etiology [Takotsubo Cardiomyopathy], Middle Aged, Prognosis, complications [Ischemic Stroke], Outcomes research, Heart Disease Risk Factors, 10209 Clinic for Cardiology, Medicine, Female, 150 Psychology, Intracranial Hemorrhages, ddc:600
Abstract

© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/., Cardiac alterations are frequently observed after acute neurological disorders. Takotsubo syndrome (TTS) represents an acute heart failure syndrome and is increasingly recognized as part of the spectrum of cardiac complications observed after neurological disorders. A systematic investigation of TTS patients with neurological disorders has not been conducted yet. The aim of the study was to expand insights regarding neurological disease entities triggering TTS and to investigate the clinical profile and outcomes of TTS patients after primary neurological disorders. The International Takotsubo Registry is an observational multicenter collaborative effort of 45 centers in 14 countries (ClinicalTrials.gov, identifier NCT01947621). All patients in the registry fulfilled International Takotsubo Diagnostic Criteria. For the present study, patients were included if complete information on acute neurological disorders were available. 2402 patients in whom complete information on acute neurological status were available were analyzed. In 161 patients (6.7%) an acute neurological disorder was identified as the preceding triggering factor. The most common neurological disorders were seizures, intracranial hemorrhage, and ischemic stroke. Time from neurological symptoms to TTS diagnosis was ≤ 2 days in 87.3% of cases. TTS patients with neurological disorders were younger, had a lower female predominance, fewer cardiac symptoms, lower left ventricular ejection fraction, and higher levels of cardiac biomarkers. TTS patients with neurological disorders had a 3.2-fold increased odds of in-hospital mortality compared to TTS patients without neurological disorders. In this large-scale study, 1 out of 15 TTS patients had an acute neurological condition as the underlying triggering factor. Our data emphasize that a wide spectrum of neurological diseases ranging from benign to life-threatening encompass TTS. The high rates of adverse events highlight the need for clinical awareness., The International Takotsubo Registry was supported by the Biss Davies Charitable Trust. Dr. Scheitz has been supported by the Corona Foundation. Dr. Templin has been supported by the H.H. Sheikh Khalifa bin Hamad Al-Thani Research Programme and the Swiss Heart Foundation.

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2021
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25. Impact of Atrial Fibrillation on Outcome in Takotsubo Syndrome: Data From the International Takotsubo Registry

Author

El‐Battrawy, Ibrahim, primary, Cammann, Victoria L., additional, Kato, Ken, additional, Szawan, Konrad A., additional, Di Vece, Davide, additional, Rossi, Aurelio, additional, Wischnewsky, Manfred, additional, Hermes‐Laufer, Julia, additional, Gili, Sebastiano, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Milosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, D’Ascenzo, Fabrizio, additional, Dichtl, Wolfgang, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, David Arroja, Jose, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K. E. Juhani, additional, Napp, L. Christian, additional, Budnik, Monika, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Kozel, Martin, additional, Tousek, Petr, additional, Winchester, David E., additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho‐Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Kobayashi, Yoshio, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H., additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Felix, Stephan B., additional, Opolski, Grzegorz, additional, Braun‐Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Katus, Hugo A., additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Bax, Jeroen J., additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Duru, Firat, additional, Borggrefe, Martin, additional, Ghadri, Jelena R., additional, Akin, Ibrahim, additional, and Templin, Christian, additional

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2021
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26. Ethnic comparison in takotsubo syndrome: novel insights from the International Takotsubo Registry

Author

Imori, Yoichi, primary, Kato, Ken, additional, Cammann, Victoria L., additional, Szawan, Konrad A., additional, Wischnewsky, Manfred, additional, Dreiding, Sara, additional, Würdinger, Michael, additional, Schönberger, Maximilian, additional, Petkova, Vanya, additional, Niederseer, David, additional, Levinson, Rena A., additional, Di Vece, Davide, additional, Gili, Sebastiano, additional, Seifert, Burkhardt, additional, Wakita, Masaki, additional, Suzuki, Noriko, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, Heiner, Susanne, additional, Knorr, Maike, additional, Jansen, Thomas, additional, Münzel, Thomas, additional, D’Ascenzo, Fabrizio, additional, Franke, Jennifer, additional, Sorici-Barb, Ioana, additional, Katus, Hugo A., additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Napp, L. Christian, additional, Bauersachs, Johann, additional, Jaguszewski, Milosz, additional, Shiomura, Reiko, additional, Nakamura, Shunichi, additional, Takano, Hitoshi, additional, Noutsias, Michel, additional, Burgdorf, Christof, additional, Ishibashi, Iwao, additional, Himi, Toshiharu, additional, Koenig, Wolfgang, additional, Schunkert, Heribert, additional, Thiele, Holger, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Pieske, Burkert M., additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Mizuno, Shingo, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Hasenfuß, Gerd, additional, Karakas, Mahir, additional, Mochizuki, Hiroki, additional, Pott, Alexander, additional, Rottbauer, Wolfgang, additional, Said, Samir M., additional, Braun-Dullaeus, Ruediger C., additional, Banning, Adrian, additional, Isogai, Toshiaki, additional, Kimura, Akihisa, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K. E. Juhani, additional, Tomita, Yasuhiro, additional, Budnik, Monika, additional, Opolski, Grzegorz, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Crea, Filippo, additional, Dichtl, Wolfgang, additional, Murakami, Tsutomu, additional, Ikari, Yuji, additional, Empen, Klaus, additional, Beug, Daniel, additional, Felix, Stephan B., additional, Delmas, Clément, additional, Lairez, Olivier, additional, Yamaguchi, Tetsuo, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Borggrefe, Martin, additional, Horowitz, John D., additional, Kozel, Martin, additional, Tousek, Petr, additional, Widimský, Petr, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Neuhaus, Michael, additional, Meyer, Philippe, additional, Arroja, Jose David, additional, Chan, Christina, additional, Bridgman, Paul, additional, Galuszka, Jan, additional, Poglajen, Gregor, additional, Carrilho-Ferreira, Pedro, additional, Pinto, Fausto J., additional, Hauck, Christian, additional, Maier, Lars S., additional, Liu, Kan, additional, Di Mario, Carlo, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Winchester, David E., additional, Ukena, Christian, additional, Böhm, Michael, additional, Bax, Jeroen J., additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Saito, Shigeru, additional, Kobayashi, Yoshio, additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Shimizu, Wataru, additional, Ghadri, Jelena R., additional, and Templin, Christian, additional

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2021
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27. Prognostic impact of acute pulmonary triggers in patients with takotsubo syndrome: new insights from the International Takotsubo Registry

Author

Kato, Ken, primary, Cammann, Victoria L., additional, Napp, L. Christian, additional, Szawan, Konrad A., additional, Micek, Jozef, additional, Dreiding, Sara, additional, Levinson, Rena A., additional, Petkova, Vanya, additional, Würdinger, Michael, additional, Patrascu, Alexandru, additional, Sumalinog, Rafael, additional, Gili, Sebastiano, additional, Clarenbach, Christian F., additional, Kohler, Malcolm, additional, Wischnewsky, Manfred, additional, Citro, Rodolfo, additional, Vecchione, Carmine, additional, Bossone, Eduardo, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Milosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, D'Ascenzo, Fabrizio, additional, Dichtl, Wolfgang, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Roffi, Marco, additional, Banning, Adrian, additional, Wolfrum, Mathias, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Budnik, Monika, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Kozel, Martin, additional, Tousek, Petr, additional, Winchester, David E., additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho‐Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Sano, Masanori, additional, Ishibashi, Iwao, additional, Takahara, Masayuki, additional, Himi, Toshiharu, additional, Kobayashi, Yoshio, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H., additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Felix, Stephan B., additional, Opolski, Grzegorz, additional, Braun‐Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Borggrefe, Martin, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Katus, Hugo A., additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Bax, Jeroen J., additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Ghadri, Jelena R., additional, and Templin, Christian, additional

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2021
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29. Autorenverzeichnis

Author

Madler, Christian, primary, Jauch, Karl-Walter, additional, Werdan, Karl, additional, Siegrist, Johannes, additional, Pajonk, Frank-Gerald, additional, Arntz, Hans-Richard, additional, Bachitis, Costas, additional, Bahr, Jan, additional, Baumeister, Rüdiger, additional, Bein, Thomas, additional, Beneker, Jörg, additional, Berzewski, Horst, additional, Bey, Tareg, additional, Böttiger, Bernd W., additional, Braun, Jörg, additional, Brockmeier, Johannes, additional, Maeder, Monika Brodmann, additional, Bruns, Christiane, additional, Buerke, Ute, additional, Buerke, Michael, additional, Carlsson, Jörg, additional, Cuneo, Alessandro, additional, Diefenbacher, Albert, additional, Dietz, Hans-Georg, additional, Doehn, Christian, additional, Dombrowsky, Wolf, additional, Ebelt, Henning, additional, Eichler, Wolfgang, additional, Ellinger, Klaus, additional, Erdmann, Detlev, additional, Exadaktylos, Aristomenis, additional, Fiebach, Jörg, additional, Fischer, Matthias, additional, Flüchter, Peter, additional, Friese, Klaus, additional, Gardemann, Joachim, additional, Genzwürker, Harald, additional, Geraedts, Max, additional, Germann, Günter, additional, Giessler, Goetz A., additional, Golombek, Ute, additional, Graeb, Christian, additional, Graf, Jürgen, additional, Grothe, Wilfried, additional, Haberl, med. Roman L., additional, Hamann, Gerhard, additional, Hansen, Ernil, additional, Härtel, Dirk, additional, Heier, Margit, additional, Heinroth, Konstantin, additional, Herkner, Harald, additional, Hörmann, Allmuth, additional, Hofmann, Friedrich, additional, Hofmann, Gunther, additional, Holzbach, Rüdiger, additional, Hosemann, Werner, additional, Hügler, Peter, additional, Hüttl, Thomas P., additional, Hüttl, Tanija K., additional, Ittner, Karl Peter, additional, Janssens, Uwe, additional, . Jehle, Peter M, additional, Jocham, Dieter, additional, Jonas, Michael, additional, Jordan, Karin, additional, Kaftan, Holger, additional, Kainer, Franz, additional, Kanz, Karl-Georg, additional, Kapfhammer, Hans-Peter, additional, Keßler, Holger, additional, Klauß, Volker, additional, Kollmann, K. H. Martin, additional, König, Carsten, additional, Kopp, Reinhard, additional, Krause, Henning, additional, Kreutzer, Thomas, additional, Krieter, Heiner, additional, Krüsmann, Marion, additional, Lackner, Christian K., additional, Laux, Tino, additional, Lehmann, Ulrich, additional, Lempp, Kattrin, additional, Lilie, Hans, additional, Link, Hartmut, additional, Löscher, Thomas, additional, Luiz, Thomas, additional, Martin, Jörg, additional, Meier, Michael, additional, Meisel, Michael, additional, Meisinger, Christa, additional, Merkel, Frank, additional, Messelken, Martin, additional, Messer, Thomas, additional, Meyer, Wolfgang, additional, Mielck, Andreas, additional, Mittlmeier, Thomas, additional, Moecke, Heinzpeter, additional, Müller, Christian, additional, Müller-Cyran, Andreas, additional, Müllner, Marcus, additional, Mutschler, Wolf-Eberhard, additional, Nerlich, Michael, additional, Nicolai, Thomas, additional, Noachtar, Soheyl, additional, Ohmann, Christian, additional, Overbeck, Maria, additional, Penning, Randolph, additional, Peschel, Oliver, additional, Pfeifer, Michael, additional, Pichler, Bodo, additional, Pohl-Meuten, Ulrike, additional, Poloczek, Stefan, additional, Röhrborn, Ansgar, additional, Roos, Reinhard, additional, Ruf, Bernhard R., additional, Ruppert, Matthias, additional, Ruß, Martin, additional, Salomon, Fred, additional, Schächinger, Ulrich, additional, Schlechtriemen, Thomas, additional, Schmauß, Max, additional, Schmidt, Hendrik, additional, Schmitt, Thomas K., additional, Schneider, Joachim, additional, Schunk, Mirjam, additional, Spöhr, Fabian, additional, Steinert, Tilmann, additional, Tebbe, Ulrich, additional, Thierbach, Andreas, additional, Tobien, Heike, additional, Trabert, Gerhard, additional, Trappe, Hans-Joachim, additional, Üner, Beyhan, additional, Ullrich, Odo-Winfried, additional, Urbach, Wolfgang, additional, Urban, Bert, additional, Laak, Ulrich van, additional, Vogel, Matthias, additional, Vogel, Peter, additional, Bergh, Martin von, additional, Knesebeck, Olaf von dem, additional, Wacker, Petra, additional, Wacker, Rüdiger, additional, Wagner, Frithjof, additional, Warnecke, Marc, additional, Weber, Manfred, additional, Weidenhagen, Rolf, additional, Weilemann, Ludwig Sacha, additional, Wenzel, Volker, additional, Wilhelm, Joachim, additional, Windisch, Christoph B., additional, Winkler, Hartmut, additional, Winter, Hauke, additional, Wolf, Hans-Heinrich, additional, Zellerhoff, Christian, additional, and Zimmermann, Heinz, additional

Published
2009
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30. Coexistence and outcome of coronary artery disease in Takotsubo syndrome

Author

Napp, L Christian, primary, Cammann, Victoria L, additional, Jaguszewski, Milosz, additional, Szawan, Konrad A, additional, Wischnewsky, Manfred, additional, Gili, Sebastiano, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, D’Ascenzo, Fabrizio, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Sorici-Barb, Ioana, additional, Noutsias, Michel, additional, Burgdorf, Christof, additional, Koenig, Wolfgang, additional, Kherad, Behrouz, additional, Sarcon, Annahita, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Arroja, Jose D, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A, additional, Vasankari, Tuija, additional, Airaksinen, K E Juhani, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Imori, Yoichi, additional, Kato, Ken, additional, Kobayashi, Yoshio, additional, Opolski, Grzegorz, additional, Budnik, Monika, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Dichtl, Wolfgang, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Horowitz, John D, additional, Polednikova, Karolina, additional, Tousek, Petr, additional, Widimský, Petr, additional, Winchester, David E, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho-Ferreira, Pedro, additional, Di Mario, Carlo, additional, Prasad, Abhiram, additional, Rihal, Charanjit S, additional, Schulze, P Christian, additional, Bianco, Matteo, additional, Crea, Filippo, additional, Borggrefe, Martin, additional, Maier, Lars S, additional, Pinto, Fausto J, additional, Braun-Dullaeus, Ruediger C, additional, Rottbauer, Wolfgang, additional, Katus, Hugo A, additional, Hasenfuß, Gerd, additional, Tschöpe, Carsten, additional, Pieske, Burkert M, additional, Thiele, Holger, additional, Schunkert, Heribert, additional, Böhm, Michael, additional, Felix, Stephan B, additional, Münzel, Thomas, additional, Bax, Jeroen J, additional, Bauersachs, Johann, additional, Braunwald, Eugene, additional, Lüscher, Thomas F, additional, Ruschitzka, Frank, additional, Ghadri, Jelena R, additional, and Templin, Christian, additional

Published
2020
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31. Age-Related Variations in Takotsubo Syndrome

Author

Cammann, Victoria L., primary, Szawan, Konrad A., additional, Stähli, Barbara E., additional, Kato, Ken, additional, Budnik, Monika, additional, Wischnewsky, Manfred, additional, Dreiding, Sara, additional, Levinson, Rena A., additional, Di Vece, Davide, additional, Gili, Sebastiano, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Meder, Benjamin, additional, Jaguszewski, Miłosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, D’Ascenzo, Fabrizio, additional, Dichtl, Wolfgang, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Roffi, Marco, additional, Banning, Adrian, additional, Wolfrum, Mathias, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Napp, L. Christian, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Poledniková, Karolina, additional, Toušek, Petr, additional, Winchester, David E., additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho-Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Kobayashi, Yoshio, additional, Shoji, Toshihiro, additional, Ishibashi, Iwao, additional, Takahara, Masayuki, additional, Himi, Toshiharu, additional, Din, Jehangir, additional, Al-Shammari, Ali, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Pestana, Gonçalo, additional, Nguyen, Thanh H., additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Felix, Stephan B., additional, Braun-Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Borggrefe, Martin, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Katus, Hugo A., additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Bax, Jeroen J., additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Ghadri, Jelena R., additional, Opolski, Grzegorz, additional, and Templin, Christian, additional

Published
2020
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32. Verzeichnis der Herausgeber und Autoren

Author

Jauch, Karl-Walter, primary, Madler, Christian, additional, Pajonk, Frank-Gerald, additional, Siegrist, Johannes, additional, Werdan, Karl, additional, Altemeyer, Karl-Heinz, additional, Arntz, Hans-Richard, additional, Bachtis, Costas, additional, Bahr, Jan, additional, Baumeister, Rüdiger, additional, Bein, Thomas, additional, Beneker, Jörg, additional, Berzewski, Horst, additional, Bey, Tareg, additional, Böttiger, Bernd W., additional, Brockmeier, Johannes, additional, Bruns, Christiane J., additional, Buerke, Ute, additional, Butollo, Willi, additional, Carlsson, Jörg, additional, Christoph, Arnd, additional, Cuneo, Alessandro, additional, Diefenbacher, Albert, additional, Dietz, Hans-Georg, additional, Doehn, Christian, additional, Dombrowsky, Wolf R., additional, Eichler, Wolfgang, additional, Ellinger, Klaus, additional, Erdmann, Detlev, additional, Exadaktylos, Aris, additional, Fischer, Matthias, additional, Forst, Helmuth, additional, Friese, Klaus, additional, Gardemann, Joachim, additional, Genzwürker, Harald, additional, Geraedts, Max, additional, Germann, Günter, additional, Giessler, Goetz A., additional, Goebel, Frank-Detlef, additional, Graeb, Christian, additional, Graf, Jürgen, additional, Gültekin, Nejla, additional, Haberl, Roman L., additional, Härtel, Dirk, additional, Hamann, Gerhard, additional, Heier, Margit, additional, Heinroth, Konstantin, additional, Hennen, Ralf, additional, Herkner, Harald, additional, Hofmann, Friedrich, additional, Hofmann, Gunter O., additional, Hofmeister, Martin, additional, Holzbach, Rüdiger, additional, Hosemann, Werner, additional, Hügler, Peter, additional, H, Thomas P., additional, Ittner, Karl Peter, additional, Janssens, Uwe, additional, Jauch, Karl-Walter, additional, Jehle, Peter, additional, Jocham, Dieter, additional, Jonas, Michael, additional, Kainer, Franz, additional, Kaftan, Holger, additional, Kapfhammer, Hans-Peter, additional, Kanz, Karl-Georg, additional, Kasprzak, Piotr M., additional, Kessler, Holger, additional, Klauß, Volker, additional, von dem Knesebeck, Olaf, additional, König, Carsten, additional, Kohler, Thomas, additional, Kollmann, Martin, additional, Kopp, Reinhard, additional, Krause, Henning, additional, van Laak, Ulrich, additional, Lackner, Christian K., additional, Laubenthal, Heinz, additional, Laux, Tino, additional, Lehmann, Ulrich, additional, Lilie, Hans, additional, Link, Hartmut, additional, Löscher, Thomas, additional, Löwel, Hannelore, additional, Luiz, Thomas, additional, Martin, Jörg, additional, Meisel, Michael, additional, Meisinger, Christa, additional, Merkel, Frank, additional, Messelken, Martin, additional, Messer, Thomas, additional, Meyer, Wolfgang, additional, Mielck, Andreas, additional, Mittlmeier, Thomas, additional, Moecke, Heinzpeter, additional, Müller, Christian, additional, Müllner, Marcus, additional, Mutschler, Wolfgang, additional, Nerlich, Michael, additional, Nicolai, Thomas, additional, Noachtar, Soheyl, additional, Ohmann, Christian, additional, Overbeck, Maria, additional, Penning, Randolph, additional, Peschel, Oliver, additional, Pfeifer, Michael, additional, Pichler, Bodo, additional, Poloczek, Stefan, additional, Preßl, Johann, additional, Prondzinsky, Roland, additional, Reith, Sebastian, additional, Roos, Reinhard, additional, Röhrborn, Ansgar, additional, Rosenow, Felix, additional, Ruf, Bernhard. R., additional, Ruppert, Matthias, additional, Ruß, Martin, additional, Salomon, Fred, additional, Schächinger, Ulrich, additional, Schlechtriemen, Thomas, additional, Schmauß, Max, additional, Schmidt, Hendrik, additional, Schmitt, Thomas K., additional, Schneider, Joachim, additional, Sefrin, Peter, additional, Sirtl, Clemens, additional, Sorges, Eckhard, additional, Spöhr, Fabian, additional, Steinert, Tilmann, additional, Tebbe, Ulrich, additional, Thierbach, Andreas, additional, Tobien, Heike, additional, Trabert, Gerhard, additional, Trappe, Hans-Joachim, additional, Ullrich, Odo-Winfried, additional, Urbach, Wolfgang, additional, Vogel, Peter, additional, Wacker, Petra, additional, Wacker, Rüdiger, additional, Wagner, Frithjof D., additional, Warnecke, Marc, additional, Wasner, Tina, additional, Weber, Manfred, additional, Weilemann, Ludwig S., additional, Windisch, Christoph B., additional, Winkler, Hartmut, additional, and Zimmermann, Heinz, additional

Published
2005
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34. Impact of aspirin on takotsubo syndrome: a propensity score-based analysis of the InterTAK Registry

Author

D'Ascenzo, Fabrizio, Gili, Sebastiano, Bertaina, Maurizio, Iannaccone, Mario, Cammann, Victoria L., Di Vece, Davide, Kato, Ken, Saglietto, Andrea, Szawan, Konrad A., Frangieh, Antonio H., Boffini, Beatrice, Annaratone, Margherita, Sarcon, Annahita, Levinson, Rena A., Franke, Jennifer, Napp, L. Christian, Jaguszewski, Milosz, Noutsias, Michel, Muenzel, Thomas, Knorr, Maike, Heiner, Susanne, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Tschoepe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Franz, Wolfgang M., Empen, Klaus, Felix, Stephan B., Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Horowitz, John D., Kozel, Martin, Tousek, Petr, Widimsky, Petr, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Biondi-Zoccai, Giuseppe, Winchester, David E., Ukena, Christian, Neuhaus, Michael, Bax, Jeroen J., Prasad, Abhiram, Di Mario, Carlo, Boehm, Michael, Gasparini, Mauro, Ruschitzka, Frank, Bossone, Eduardo, Citro, Rodolfo, Rinaldi, Mauro, De Ferrari, Gaetano Maria, Luscher, Thomas, Ghadri, Jelena R., Templin, Christian, D'Ascenzo, Fabrizio, Gili, Sebastiano, Bertaina, Maurizio, Iannaccone, Mario, Cammann, Victoria L., Di Vece, Davide, Kato, Ken, Saglietto, Andrea, Szawan, Konrad A., Frangieh, Antonio H., Boffini, Beatrice, Annaratone, Margherita, Sarcon, Annahita, Levinson, Rena A., Franke, Jennifer, Napp, L. Christian, Jaguszewski, Milosz, Noutsias, Michel, Muenzel, Thomas, Knorr, Maike, Heiner, Susanne, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Tschoepe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Franz, Wolfgang M., Empen, Klaus, Felix, Stephan B., Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Horowitz, John D., Kozel, Martin, Tousek, Petr, Widimsky, Petr, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Biondi-Zoccai, Giuseppe, Winchester, David E., Ukena, Christian, Neuhaus, Michael, Bax, Jeroen J., Prasad, Abhiram, Di Mario, Carlo, Boehm, Michael, Gasparini, Mauro, Ruschitzka, Frank, Bossone, Eduardo, Citro, Rodolfo, Rinaldi, Mauro, De Ferrari, Gaetano Maria, Luscher, Thomas, Ghadri, Jelena R., and Templin, Christian

Abstract

AimsThe aim of the present study was to investigate the impact of aspirin on prognosis in takotsubo syndrome (TTS). Methods and resultsPatients from the International Takotsubo (InterTAK) Registry were categorized into two groups based on aspirin prescription at discharge. A comparison of clinical outcomes between groups was performed using an adjusted analysis with propensity score (PS) stratification; results from the unadjusted analysis were also reported to note the effect of the PS adjustment. Major adverse cardiac and cerebrovascular events (MACCE: a composite of death, myocardial infarction, TTS recurrence, stroke or transient ischaemic attack) were assessed at 30-day and 5-year follow-up. A total of 1533 TTS patients with known status regarding aspirin prescription at discharge were included. According to the adjusted analysis based on PS stratification, aspirin was not associated with a lower hazard of MACCE at 30-day [hazard ratio (HR) 1.24, 95% confidence interval (CI) 0.50-3.04, P = 0.64] or 5-year follow-up (HR 1.11, 95% CI 0.78-1.58, P = 0.58). These results were confirmed by sensitivity analyses performed with alternative PS-based methods, i.e. covariate adjustment and inverse probability of treatment weighting. ConclusionIn the present study, no association was found between aspirin use in TTS patients and a reduced risk of MACCE at 30-day and 5-year follow-up. These findings should be confirmed in adequately powered randomized controlled trials. Identifier: NCT01947621.

Published
2020

35. Age -Related Variations in Takotsubo Syndrome

Author

Cammann, Victoria L., Szawan, Konrad A., Stahli, Barbara E., Kato, Ken, Budnik, Monika, Wischnewsky, Manfred, Dreiding, Sara, Levinson, Rena A., Di Vece, Davide, Gili, Sebastiano, Citro, Rodolfo, Bossone, Eduardo, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Milosz, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, D'Ascenzo, Fabrizio, Dichtl, Wolfgang, Burgdorf, Christof, Kherad, Behrouz, Tschope, Carsten, Sarcon, Annahita, Shinbane, Jerold, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Koenig, Wolfgang, Pott, Alexander, Meyer, Philippe, Roffi, Marco, Banning, Adrian, Wolfrum, Mathias, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Napp, L. Christian, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Polednikova, Karolina, Tous, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Kobayashi, Yoshio, Shoji, Toshihiro, Ishibashi, Iwao, Takahara, Masayuki, Himi, Toshiharu, Din, Jehangir, Al-Shammari, Ali, Prasad, Abhiram, Rihal, Charanjit S., Liu, Kan, Schulze, P. Christian, Bianco, Matteo, Jorg, Lucas, Rickli, Hans, Pestana, Goncalo, Nguyen, Thanh H., Bohm, Michael, Maier, Lars S., Pinto, Fausto J., Widimsky, Petr, Felix, Stephan B., Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Hasenfuss, Gerd, Pieske, Burkert M., Schunkert, Heribert, Borggrefe, Martin, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A., Horowitz, John D., Di Mario, Carlo, Muenzel, Thomas, Crea, Filippo, Bax, Jeroen J., Luscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Opolski, Grzegorz, Templin, Christian, Cammann, Victoria L., Szawan, Konrad A., Stahli, Barbara E., Kato, Ken, Budnik, Monika, Wischnewsky, Manfred, Dreiding, Sara, Levinson, Rena A., Di Vece, Davide, Gili, Sebastiano, Citro, Rodolfo, Bossone, Eduardo, Neuhaus, Michael, Franke, Jennifer, Meder, Benjamin, Jaguszewski, Milosz, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, D'Ascenzo, Fabrizio, Dichtl, Wolfgang, Burgdorf, Christof, Kherad, Behrouz, Tschope, Carsten, Sarcon, Annahita, Shinbane, Jerold, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Koenig, Wolfgang, Pott, Alexander, Meyer, Philippe, Roffi, Marco, Banning, Adrian, Wolfrum, Mathias, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Napp, L. Christian, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Polednikova, Karolina, Tous, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Kobayashi, Yoshio, Shoji, Toshihiro, Ishibashi, Iwao, Takahara, Masayuki, Himi, Toshiharu, Din, Jehangir, Al-Shammari, Ali, Prasad, Abhiram, Rihal, Charanjit S., Liu, Kan, Schulze, P. Christian, Bianco, Matteo, Jorg, Lucas, Rickli, Hans, Pestana, Goncalo, Nguyen, Thanh H., Bohm, Michael, Maier, Lars S., Pinto, Fausto J., Widimsky, Petr, Felix, Stephan B., Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Hasenfuss, Gerd, Pieske, Burkert M., Schunkert, Heribert, Borggrefe, Martin, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A., Horowitz, John D., Di Mario, Carlo, Muenzel, Thomas, Crea, Filippo, Bax, Jeroen J., Luscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Opolski, Grzegorz, and Templin, Christian

Published
2020

36. Coexistence and outcome of coronary artery disease in Takotsubo syndrome

Author

Napp, L. Christian, Cammann, Victoria L., Jaguszewski, Milosz, Szawan, Konrad A., Wischnewsky, Manfred, Gili, Sebastiano, Knorr, Maike, Heiner, Susanne, Citro, Rodolfo, Bossone, Eduardo, D'Ascenzo, Fabrizio, Neuhaus, Michael, Franke, Jennifer, Sorici-Barb, Ioana, Noutsias, Michel, Burgdorf, Christof, Koenig, Wolfgang, Kherad, Behrouz, Sarcon, Annahita, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Pott, Alexander, Meyer, Philippe, Arroja, Jose D., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Imori, Yoichi, Kato, Ken, Kobayashi, Yoshio, Opolski, Grzegorz, Budnik, Monika, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Horowitz, John D., Polednikova, Karolina, Tousek, Petr, Widimsky, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Di Mario, Carlo, Prasad, Abhiram, Rihal, Charanjit S., Schulze, P. Christian, Bianco, Matteo, Crea, Filippo, Borggrefe, Martin, Maier, Lars S., Pinto, Fausto J., Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Katus, Hugo A., Hasenfuss, Gerd, Tschoepe, Carsten, Pieske, Burkert M., Thiele, Holger, Schunkert, Heribert, Boehm, Michael, Felix, Stephan B., Muenzel, Thomas, Bax, Jeroen J., Bauersachs, Johann, Braunwald, Eugene, Luescher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Templin, Christian, Napp, L. Christian, Cammann, Victoria L., Jaguszewski, Milosz, Szawan, Konrad A., Wischnewsky, Manfred, Gili, Sebastiano, Knorr, Maike, Heiner, Susanne, Citro, Rodolfo, Bossone, Eduardo, D'Ascenzo, Fabrizio, Neuhaus, Michael, Franke, Jennifer, Sorici-Barb, Ioana, Noutsias, Michel, Burgdorf, Christof, Koenig, Wolfgang, Kherad, Behrouz, Sarcon, Annahita, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Pott, Alexander, Meyer, Philippe, Arroja, Jose D., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Hauck, Christian, Paolini, Carla, Bilato, Claudio, Imori, Yoichi, Kato, Ken, Kobayashi, Yoshio, Opolski, Grzegorz, Budnik, Monika, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Horowitz, John D., Polednikova, Karolina, Tousek, Petr, Widimsky, Petr, Winchester, David E., Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Carrilho-Ferreira, Pedro, Di Mario, Carlo, Prasad, Abhiram, Rihal, Charanjit S., Schulze, P. Christian, Bianco, Matteo, Crea, Filippo, Borggrefe, Martin, Maier, Lars S., Pinto, Fausto J., Braun-Dullaeus, Ruediger C., Rottbauer, Wolfgang, Katus, Hugo A., Hasenfuss, Gerd, Tschoepe, Carsten, Pieske, Burkert M., Thiele, Holger, Schunkert, Heribert, Boehm, Michael, Felix, Stephan B., Muenzel, Thomas, Bax, Jeroen J., Bauersachs, Johann, Braunwald, Eugene, Luescher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., and Templin, Christian

Abstract

Aims Takotsubo syndrome (US) is an acute heart failure syndrome, which shares many features with acute coronary syndrome (ACS). Although TTS was initially described with angiographically normal coronary arteries, smaller studies recently indicated a potential coexistence of coronary artery disease (CAD) in US patients. This study aimed to determine the coexistence, features, and prognostic role of CAD in a large cohort of patients with US. Methods and results Coronary anatomy and CAD were studied in patients diagnosed with US. Inclusion criteria were compliance with the International Takotsubo Diagnostic Criteria for TTS, and availability of original coronary angiographies with ventriculography performed during the acute phase. Exclusion criteria were missing views, poor quality of angiography loops, and angiography without ventriculography. A total of 1016 US patients were studied. Of those, 23.0% had obstructive CAD, 41.2% had non -obstructive CAD, and 35.7% had angiographically normal coronary arteries. A total of 47 patients (4.6%) underwent percutaneous coronary intervention, and 3 patients had acute and 8 had chronic coronary artery occlusion concomitant with US, respectively. The presence of CAD was associated with increased incidence of shock, ventilation, and death from any cause. After adjusting for confounders, the presence of obstructive CAD was associated with mortality at 30 days. Takotsubo syndrome patients with obstructive CAD were at comparable risk for shock and death and nearly at twice the risk for ventilation compared to an age- and sex-matched ACS cohort. Conclusions Coronary artery disease frequently coexists in US patients, presents with the whole spectrum of coronary pathology including acute coronary occlusion, and is associated with adverse outcome.

Published
2020

37. Improved survival of patients with coronary artery disease and low ejection fraction with ICD implantation versus conventional therapy in a real world survey

Author

Aschenbrenner Timo, Brockmeier Johannes, Bramlage Peter, Fimmers Rolf, Cuneo Alessandro, Hochreuther Stefan, Zemmrich Claudia, and Tebbe Ulrich

Subjects
Implantable cardioverter defibrillator, Cohort study, Myocardial infarction, Medicine, Biology (General), QH301-705.5, Science (General), Q1-390
Abstract

Abstract Background Coronary artery disease (CAD) is associated with an increased risk for sudden cardiac death. Randomized controlled trials have shown that implantable cardioverter defibrillators (ICD) improve life expectancy unless they are implanted within the first days after an acute myocardial infarction and guidelines recommend their use. We aimed to validate that these results also apply to patients of a typical community hospital in Germany. Methods This was a retrospective analysis of patients undergoing coronary angiography in the Lippe-Detmold Hospital between 2003 and 2006. They had to have significant CAD and an ejection fraction (EF) ≤ 35% and no acute myocardial infarction within 28 days of implantation and no history of ventricular fibrillation. Results 213 patients were included; 70 of which received an ICD. Patients with an ICD implantation were younger (64.8 ± 9.9 vs. 67.9 ± 9.8 years; p = 0.034), had single vessel CAD more frequently (22.9 vs. 11.2%; p = 0.025) and a lower EF (26.7 ± 6.3 vs. 29.1 ± 4.6%; p = 0.006). Hospital readmissions were comparable between the ICD and the control group (68.6 vs. 72.0%; p = 0.602). ICD therapy was associated with a considerable survival benefit compared to conventional therapy (HR 0.52; 95%CI 0.29-0.93; p = 0.027) in a Cox-Proportional Hazards Regression analysis. Conclusions Appreciating the potential limitations of retrospective studies, we found that ICD use was associated with improved survival in patients with significant CAD and an EF

Published
2012
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38. Impact of aspirin on takotsubo syndrome: a propensity score‐based analysis of the InterTAK Registry

Author

D'Ascenzo, Fabrizio, primary, Gili, Sebastiano, additional, Bertaina, Maurizio, additional, Iannaccone, Mario, additional, Cammann, Victoria L., additional, Di Vece, Davide, additional, Kato, Ken, additional, Saglietto, Andrea, additional, Szawan, Konrad A., additional, Frangieh, Antonio H., additional, Boffini, Beatrice, additional, Annaratone, Margherita, additional, Sarcon, Annahita, additional, Levinson, Rena A., additional, Franke, Jennifer, additional, Napp, L. Christian, additional, Jaguszewski, Milosz, additional, Noutsias, Michel, additional, Münzel, Thomas, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Katus, Hugo A., additional, Burgdorf, Christof, additional, Schunkert, Heribert, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Tschöpe, Carsten, additional, Pieske, Burkert M., additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Hasenfuß, Gerd, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Rottbauer, Wolfgang, additional, Said, Samir M., additional, Braun‐Dullaeus, Ruediger C., additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Opolski, Grzegorz, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Crea, Filippo, additional, Dichtl, Wolfgang, additional, Franz, Wolfgang M., additional, Empen, Klaus, additional, Felix, Stephan B., additional, Delmas, Clément, additional, Lairez, Olivier, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Borggrefe, Martin, additional, Horowitz, John D., additional, Kozel, Martin, additional, Tousek, Petr, additional, Widimský, Petr, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Biondi‐Zoccai, Giuseppe, additional, Winchester, David E., additional, Ukena, Christian, additional, Neuhaus, Michael, additional, Bax, Jeroen J., additional, Prasad, Abhiram, additional, Di Mario, Carlo, additional, Böhm, Michael, additional, Gasparini, Mauro, additional, Ruschitzka, Frank, additional, Bossone, Eduardo, additional, Citro, Rodolfo, additional, Rinaldi, Mauro, additional, De Ferrari, Gaetano Maria, additional, Lüscher, Thomas, additional, Ghadri, Jelena R., additional, and Templin, Christian, additional

Published
2019
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39. Clinical Predictors and Prognostic Impact of Recovery of Wall Motion Abnormalities in Takotsubo Syndrome: Results From the International Takotsubo Registry

Author

Jurisic, Stjepan, primary, Gili, Sebastiano, additional, Cammann, Victoria L., additional, Kato, Ken, additional, Szawan, Konrad A., additional, D'Ascenzo, Fabrizio, additional, Jaguszewski, Milosz, additional, Bossone, Eduardo, additional, Citro, Rodolfo, additional, Sarcon, Annahita, additional, Napp, L. Christian, additional, Franke, Jennifer, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Burgdorf, Christof, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Kherad, Behrouz, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Meyer, Philippe, additional, Arroja, Jose David, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K. E. Juhani, additional, Dworakowski, Rafal, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Dichtl, Wolfgang, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Kozel, Martin, additional, Tousek, Petr, additional, Winchester, David E., additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Carrilho‐Ferreira, Pedro, additional, Pinto, Fausto J., additional, Opolski, Grzegorz, additional, MacCarthy, Philip, additional, Kobayashi, Yoshio, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Widimský, Petr, additional, Horowitz, John D., additional, Di Mario, Carlo, additional, Crea, Filippo, additional, Tschöpe, Carsten, additional, Pieske, Burkert M., additional, Hasenfuß, Gerd, additional, Rottbauer, Wolfgang, additional, Braun‐Dullaeus, Ruediger C., additional, Felix, Stephan B., additional, Borggrefe, Martin, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Katus, Hugo A., additional, Schunkert, Heribert, additional, Münzel, Thomas, additional, Böhm, Michael, additional, Bax, Jeroen J., additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Ghadri, Jelena R., additional, and Templin, Christian, additional

Published
2019
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40. Prediction of short‐ and long‐term mortality in takotsubo syndrome: the InterTAK Prognostic Score

Author

Wischnewsky, Manfred B., primary, Candreva, Alessandro, additional, Bacchi, Beatrice, additional, Cammann, Victoria L., additional, Kato, Ken, additional, Szawan, Konrad A., additional, Gili, Sebastiano, additional, D'Ascenzo, Fabrizio, additional, Dichtl, Wolfgang, additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, Neuhaus, Michael, additional, Franke, Jennifer, additional, Sorici‐Barb, Ioana, additional, Jaguszewski, Milosz, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Burgdorf, Christof, additional, Kherad, Behrouz, additional, Tschöpe, Carsten, additional, Sarcon, Annahita, additional, Shinbane, Jerold, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Pott, Alexander, additional, Meyer, Philippe, additional, Arroja, Jose David, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Napp, L. Christian, additional, Budnik, Monika, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Chan, Christina, additional, Bridgman, Paul, additional, Beug, Daniel, additional, Delmas, Clément, additional, Lairez, Olivier, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Kozel, Martin, additional, Tousek, Petr, additional, Winchester, David E., additional, Galuszka, Jan, additional, Ukena, Christian, additional, Poglajen, Gregor, additional, Carrilho‐Ferreira, Pedro, additional, Hauck, Christian, additional, Paolini, Carla, additional, Bilato, Claudio, additional, Prasad, Abhiram, additional, Rihal, Charanjit S., additional, Liu, Kan, additional, Schulze, P. Christian, additional, Bianco, Matteo, additional, Jörg, Lucas, additional, Rickli, Hans, additional, Nguyen, Thanh H., additional, Kobayashi, Yoshio, additional, Böhm, Michael, additional, Maier, Lars S., additional, Pinto, Fausto J., additional, Widimský, Petr, additional, Borggrefe, Martin, additional, Felix, Stephan B., additional, Opolski, Grzegorz, additional, Braun‐Dullaeus, Ruediger C., additional, Rottbauer, Wolfgang, additional, Hasenfuß, Gerd, additional, Pieske, Burkert M., additional, Schunkert, Heribert, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Katus, Hugo A., additional, Horowitz, John, additional, Di Mario, Carlo, additional, Münzel, Thomas, additional, Crea, Filippo, additional, Bax, Jeroen J., additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Ghadri, Jelena R., additional, and Templin, Christian, additional

Published
2019
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41. Clinical Features and Outcomes of Patients With Malignancy and Takotsubo Syndrome: Observations From the International Takotsubo Registry

Author

Cammann, Victoria L., primary, Sarcon, Annahita, additional, Ding, Katharina J., additional, Seifert, Burkhardt, additional, Kato, Ken, additional, Di Vece, Davide, additional, Szawan, Konrad A., additional, Gili, Sebastiano, additional, Jurisic, Stjepan, additional, Bacchi, Beatrice, additional, Micek, Jozef, additional, Frangieh, Antonio H., additional, Napp, L. Christian, additional, Jaguszewski, Milosz, additional, Bossone, Eduardo, additional, Citro, Rodolfo, additional, D'Ascenzo, Fabrizio, additional, Franke, Jennifer, additional, Noutsias, Michel, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Burgdorf, Christof, additional, Koenig, Wolfgang, additional, Thiele, Holger, additional, Tschöpe, Carsten, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Karakas, Mahir, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K. E. Juhani, additional, Dworakowski, Rafal, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Dichtl, Wolfgang, additional, Delmas, Clément, additional, Lairez, Olivier, additional, Horowitz, John D., additional, Kozel, Martin, additional, Widimský, Petr, additional, Tousek, Petr, additional, Winchester, David E., additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, El‐Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Ukena, Christian, additional, Bauersachs, Johann, additional, Pieske, Burkert M., additional, Hasenfuß, Gerd, additional, Rottbauer, Wolfgang, additional, Braun‐Dullaeus, Ruediger C., additional, Opolski, Grzegorz, additional, MacCarthy, Philip, additional, Felix, Stephan B., additional, Borggrefe, Martin, additional, Di Mario, Carlo, additional, Crea, Filippo, additional, Katus, Hugo A., additional, Schunkert, Heribert, additional, Münzel, Thomas, additional, Böhm, Michael, additional, Bax, Jeroen J., additional, Prasad, Abhiram, additional, Shinbane, Jerold, additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, Ghadri, Jelena R., additional, and Templin, Christian, additional

Published
2019
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42. Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry

Author

Gili, Sebastiano, primary, Cammann, Victoria L, additional, Schlossbauer, Susanne A, additional, Kato, Ken, additional, D’Ascenzo, Fabrizio, additional, Di Vece, Davide, additional, Jurisic, Stjepan, additional, Micek, Jozef, additional, Obeid, Slayman, additional, Bacchi, Beatrice, additional, Szawan, Konrad A, additional, Famos, Flurina, additional, Sarcon, Annahita, additional, Levinson, Rena, additional, Ding, Katharina J, additional, Seifert, Burkhardt, additional, Lenoir, Olivia, additional, Bossone, Eduardo, additional, Citro, Rodolfo, additional, Franke, Jennifer, additional, Napp, L Christian, additional, Jaguszewski, Milosz, additional, Noutsias, Michel, additional, Münzel, Thomas, additional, Knorr, Maike, additional, Heiner, Susanne, additional, Katus, Hugo A, additional, Burgdorf, Christof, additional, Schunkert, Heribert, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Tschöpe, Carsten, additional, Pieske, Burkert M, additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Hasenfuß, Gerd, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Rottbauer, Wolfgang, additional, Said, Samir M, additional, Braun-Dullaeus, Ruediger C, additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A, additional, Vasankari, Tuija, additional, Airaksinen, K E Juhani, additional, Opolski, Grzegorz, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Crea, Filippo, additional, Dichtl, Wolfgang, additional, Empen, Klaus, additional, Felix, Stephan B, additional, Delmas, Clément, additional, Lairez, Olivier, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Borggrefe, Martin, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Horowitz, John D, additional, Kozel, Martin, additional, Tousek, Petr, additional, Widimský, Petr, additional, Winchester, David E, additional, Ukena, Christian, additional, Gaita, Fiorenzo, additional, Di Mario, Carlo, additional, Wischnewsky, Manfred B, additional, Bax, Jeroen J, additional, Prasad, Abhiram, additional, Böhm, Michael, additional, Ruschitzka, Frank, additional, Lüscher, Thomas F, additional, Ghadri, Jelena R, additional, and Templin, Christian, additional

Published
2019
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43. Clinical Features and Outcomes of Patients With Malignancy and Takotsubo Syndrome: Observations From the International Takotsubo Registry

Author

Cammann, Victoria L., Sarcon, Annahita, Ding, Katharina J., Seifert, Burkhardt, Kato, Ken, Di Vece, Davide, Szawan, Konrad A., Gili, Sebastiano, Jurisic, Stjepan, Bacchi, Beatrice, Micek, Jozef, Frangieh, Antonio H., Napp, L. Christian, Jaguszewski, Milosz, Bossone, Eduardo, Citro, Rodolfo, D'Ascenzo, Fabrizio, Franke, Jennifer, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, Burgdorf, Christof, Koenig, Wolfgang, Thiele, Holger, Tschope, Carsten, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Dworakowski, Rafal, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Delmas, Clement, Lairez, Olivier, Horowitz, John D., Kozel, Martin, Widimsky, Petr, Tousek, Petr, Winchester, David E., Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Ukena, Christian, Bauersachs, Johann, Pieske, Burkert M., Hasenfuss, Gerd, Rottbauer, Wolfgang, Braun-Dullaeus, Ruediger C., Opolski, Grzegorz, MacCarthy, Philip, Felix, Stephan B., Borggrefe, Martin, Di Mario, Carlo, Crea, Filippo, Katus, Hugo A., Schunkert, Heribert, Munzel, Thomas, Bohm, Michael, Bax, Jeroen J., Prasad, Abhiram, Shinbane, Jerold, Luscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Templin, Christian, Cammann, Victoria L., Sarcon, Annahita, Ding, Katharina J., Seifert, Burkhardt, Kato, Ken, Di Vece, Davide, Szawan, Konrad A., Gili, Sebastiano, Jurisic, Stjepan, Bacchi, Beatrice, Micek, Jozef, Frangieh, Antonio H., Napp, L. Christian, Jaguszewski, Milosz, Bossone, Eduardo, Citro, Rodolfo, D'Ascenzo, Fabrizio, Franke, Jennifer, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, Burgdorf, Christof, Koenig, Wolfgang, Thiele, Holger, Tschope, Carsten, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Dworakowski, Rafal, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Delmas, Clement, Lairez, Olivier, Horowitz, John D., Kozel, Martin, Widimsky, Petr, Tousek, Petr, Winchester, David E., Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Ukena, Christian, Bauersachs, Johann, Pieske, Burkert M., Hasenfuss, Gerd, Rottbauer, Wolfgang, Braun-Dullaeus, Ruediger C., Opolski, Grzegorz, MacCarthy, Philip, Felix, Stephan B., Borggrefe, Martin, Di Mario, Carlo, Crea, Filippo, Katus, Hugo A., Schunkert, Heribert, Munzel, Thomas, Bohm, Michael, Bax, Jeroen J., Prasad, Abhiram, Shinbane, Jerold, Luscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., and Templin, Christian

Abstract

Background-Clinical characteristics and outcomes of takotsubo syndrome (US) patients with malignancy have not been fully elucidated. This study sought to explore differences in clinical characteristics and to investigate short- and long-term outcomes in TTS patients with or without malignancy. Methods and Results-ITS patients were enrolled from the International Takotsubo Registry. The TTS cohort was divided into patients with and without malignancy to investigate differences in clinical characteristics and to assess short- and long-term mortality. A subanalysis was performed comparing long-term mortality between a subset of TTS patients with or without malignancy and acute coronary syndrome (ACS) patients with or without malignancy. Malignancy was observed in 16.6% of 1604 TTS patients. Patients with malignancy were older and more likely to have physical triggers, but less likely to have emotional triggers compared with those without malignancy. Long-term mortality was higher in patients with malignancy (P<0.001), while short-term outcome was comparable (P=0.17). In a subanalysis, long-term mortality was comparable between TTS patients with malignancies and ACS patients with malignancies (P=0.13). Malignancy emerged as an independent predictor of long-term mortality. Conclusions-A substantial number of TTS patients show an association with malignancy. History of malignancy might increase the risk for TTS, and therefore, appropriate screening for malignancy should be considered in these patients.

Published
2019

44. Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry

Author

Gili, Sebastiano, Cammann, Victoria L., Schlossbauer, Susanne A., Kato, Ken, D'Ascenzo, Fabrizio, Di Vece, Davide, Jurisic, Stjepan, Micek, Jozef, Obeid, Slayman, Bacchi, Beatrice, Szawan, Konrad A., Famos, Flurina, Sarcon, Annahita, Levinson, Rena, Ding, Katharina J., Seifert, Burkhardt, Lenoir, Olivia, Bossone, Eduardo, Citro, Rodolfo, Franke, Jennifer, Napp, L. Christian, Jaguszewski, Milosz, Noutsias, Michel, Muenzel, Thomas, Knorr, Maike, Heiner, Susanne, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Tschoepe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Empen, Klaus, Felix, Stephan B., Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Horowitz, John D., Kozel, Martin, Tousek, Petr, Widimsky, Petr, Winchester, David E., Ukena, Christian, Gaita, Fiorenzo, Di Mario, Carlo, Wischnewsky, Manfred B., Bax, Jeroen J., Prasad, Abhiram, Boehm, Michael, Ruschitzka, Frank, Luescher, Thomas F., Ghadri, Jelena R., Templin, Christian, Gili, Sebastiano, Cammann, Victoria L., Schlossbauer, Susanne A., Kato, Ken, D'Ascenzo, Fabrizio, Di Vece, Davide, Jurisic, Stjepan, Micek, Jozef, Obeid, Slayman, Bacchi, Beatrice, Szawan, Konrad A., Famos, Flurina, Sarcon, Annahita, Levinson, Rena, Ding, Katharina J., Seifert, Burkhardt, Lenoir, Olivia, Bossone, Eduardo, Citro, Rodolfo, Franke, Jennifer, Napp, L. Christian, Jaguszewski, Milosz, Noutsias, Michel, Muenzel, Thomas, Knorr, Maike, Heiner, Susanne, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Tschoepe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Empen, Klaus, Felix, Stephan B., Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Horowitz, John D., Kozel, Martin, Tousek, Petr, Widimsky, Petr, Winchester, David E., Ukena, Christian, Gaita, Fiorenzo, Di Mario, Carlo, Wischnewsky, Manfred B., Bax, Jeroen J., Prasad, Abhiram, Boehm, Michael, Ruschitzka, Frank, Luescher, Thomas F., Ghadri, Jelena R., and Templin, Christian

Abstract

Aims We aimed to evaluate the frequency, clinical features, and prognostic implications of cardiac arrest (CA) in takotsubo syndrome (TTS). Methods and results We reviewed the records of patients with CA and known heart rhythm from the International Takotsubo Registry. The main outcomes were 60-day and 5-year mortality. In addition, predictors of mortality and predictors of CA during the acute TTS phase were assessed. Of 2098 patients, 103 patients with CA and known heart rhythm during CA were included. Compared with patients without CA, CA patients were more likely to be younger, male, and have apical TTS, atrial fibrillation (AF), neurologic comorbidities, physical triggers, and longer corrected QT-interval and lower left ventricular ejection fraction on admission. In all, 57.1% of patients with CA at admission had ventricular fibrillation/tachycardia, while 73.7% of patients with CA in the acute phase had asystole/pulseless electrical activity. Patients with CA showed higher 60-day (40.3% vs. 4.0%, P < 0.001) and 5-year mortality (68.9% vs. 16.7%, P < 0.001) than patients without CA. T-wave inversion and intracranial haemorrhage were independently associated with higher 60-day mortality after CA, whereas female gender was associated with lower 60-day mortality. In the acute phase, CA occurred less frequently in females and more frequently in patients with AF, ST-segment elevation, and higher C-reactive protein on admission. Conclusions Cardiac arrest is relatively frequent in TTS and is associated with higher short- and long-term mortality. Clinical and electrocardiographic parameters independently predicted mortality after CA.

Published
2019

45. Clinical Predictors and Prognostic Impact of Recovery of Wall Motion Abnormalities in Takotsubo Syndrome: Results From the International Takotsubo Registry

Author

Jurisic, Stjepan, Gili, Sebastiano, Cammann, Victoria L., Kato, Ken, Szawan, Konrad A., D'Ascenzo, Fabrizio, Jaguszewski, Milosz, Bossone, Eduardo, Citro, Rodolfo, Sarcon, Annahita, Napp, L. Christian, Franke, Jennifer, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, Burgdorf, Christof, Koenig, Wolfgang, Pott, Alexander, Kherad, Behrouz, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Meyer, Philippe, Arroja, Jose David, Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Dworakowski, Rafal, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, Kozel, Martin, Tousek, Petr, Winchester, David E., Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Paolini, Carla, Bilato, Claudio, Carrilho-Ferreira, Pedro, Pinto, Fausto J., Opolski, Grzegorz, MacCarthy, Philip, Kobayashi, Yoshio, Prasad, Abhiram, Rihal, Charanjit S., Widimsky, Petr, Horowitz, John D., Di Mario, Carlo, Crea, Filippo, Tschope, Carsten, Pieske, Burkert M., Hasenfuss, Gerd, Rottbauer, Wolfgang, Braun-Dullaeus, Ruediger C., Felix, Stephan B., Borggrefe, Martin, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A., Schunkert, Heribert, Muenzel, Thomas, Bohm, Michael, Bax, Jeroen J., Luscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., Templin, Christian, Jurisic, Stjepan, Gili, Sebastiano, Cammann, Victoria L., Kato, Ken, Szawan, Konrad A., D'Ascenzo, Fabrizio, Jaguszewski, Milosz, Bossone, Eduardo, Citro, Rodolfo, Sarcon, Annahita, Napp, L. Christian, Franke, Jennifer, Noutsias, Michel, Knorr, Maike, Heiner, Susanne, Burgdorf, Christof, Koenig, Wolfgang, Pott, Alexander, Kherad, Behrouz, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Karakas, Mahir, Meyer, Philippe, Arroja, Jose David, Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Dworakowski, Rafal, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Dichtl, Wolfgang, Chan, Christina, Bridgman, Paul, Beug, Daniel, Delmas, Clement, Lairez, Olivier, Kozel, Martin, Tousek, Petr, Winchester, David E., Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, El-Battrawy, Ibrahim, Akin, Ibrahim, Galuszka, Jan, Ukena, Christian, Poglajen, Gregor, Paolini, Carla, Bilato, Claudio, Carrilho-Ferreira, Pedro, Pinto, Fausto J., Opolski, Grzegorz, MacCarthy, Philip, Kobayashi, Yoshio, Prasad, Abhiram, Rihal, Charanjit S., Widimsky, Petr, Horowitz, John D., Di Mario, Carlo, Crea, Filippo, Tschope, Carsten, Pieske, Burkert M., Hasenfuss, Gerd, Rottbauer, Wolfgang, Braun-Dullaeus, Ruediger C., Felix, Stephan B., Borggrefe, Martin, Thiele, Holger, Bauersachs, Johann, Katus, Hugo A., Schunkert, Heribert, Muenzel, Thomas, Bohm, Michael, Bax, Jeroen J., Luscher, Thomas F., Ruschitzka, Frank, Ghadri, Jelena R., and Templin, Christian

Abstract

Background-Left ventricular (LV) recovery in takotsubo syndrome (TTS) occurs over a wide-ranging interval, varying from hours to weeks. We sought to investigate the clinical predictors and prognostic impact of recovery time for TTS patients. Methods and Results-TTS patients from the International Takotsubo Registry were included in this study. Cut-off for early LV recovery was determined to be 10 days after the acute event. Multivariable logistic regression was used to assess factors associated with the absence of early recovery. In-hospital outcomes and 1-year mortality were compared for patients with versus without early recovery. We analyzed 406 patients with comprehensive and serial imaging data regarding time to recovery. Of these, 191 (47.0%) had early LV recovery and 215 (53.0%) demonstrated late LV improvement. Patients without early recovery were more often male (12.6% versus 5.2%; P=0.011) and presented more frequently with typical TTS (76.3% versus 67.0%, P=0.040). Cardiac and inflammatory markers were higher in patients without early recovery than in those with early recovery. Patients without early recovery showed unfavorable 1-year outcome compared with patients with early recovery (P=0.003). On multiple logistic regression, male sex, LV ejection fraction <45%, and acute neurologic disorders were associated with the absence of early recovery. Conclusions-TTS patients without early LV recovery have different clinical characteristics and less favorable 1-year outcome compared with patients with early recovery. The factors associated with the absence of early recovery included male sex, reduced LV ejection fraction, and acute neurologic events.

Published
2019

46. Long-Term Prognosis of Patients With Takotsubo Syndrome

Author

Ghadri, Jelena R., primary, Kato, Ken, additional, Cammann, Victoria L., additional, Gili, Sebastiano, additional, Jurisic, Stjepan, additional, Di Vece, Davide, additional, Candreva, Alessandro, additional, Ding, Katharina J., additional, Micek, Jozef, additional, Szawan, Konrad A., additional, Bacchi, Beatrice, additional, Bianchi, Rahel, additional, Levinson, Rena A., additional, Wischnewsky, Manfred, additional, Seifert, Burkhardt, additional, Schlossbauer, Susanne A., additional, Citro, Rodolfo, additional, Bossone, Eduardo, additional, Münzel, Thomas, additional, Knorr, Maike, additional, Heiner, Susanne, additional, D’Ascenzo, Fabrizio, additional, Franke, Jennifer, additional, Sarcon, Annahita, additional, Napp, L. Christian, additional, Jaguszewski, Milosz, additional, Noutsias, Michel, additional, Katus, Hugo A., additional, Burgdorf, Christof, additional, Schunkert, Heribert, additional, Thiele, Holger, additional, Bauersachs, Johann, additional, Tschöpe, Carsten, additional, Pieske, Burkert M., additional, Rajan, Lawrence, additional, Michels, Guido, additional, Pfister, Roman, additional, Cuneo, Alessandro, additional, Jacobshagen, Claudius, additional, Hasenfuß, Gerd, additional, Karakas, Mahir, additional, Koenig, Wolfgang, additional, Rottbauer, Wolfgang, additional, Said, Samir M., additional, Braun-Dullaeus, Ruediger C., additional, Banning, Adrian, additional, Cuculi, Florim, additional, Kobza, Richard, additional, Fischer, Thomas A., additional, Vasankari, Tuija, additional, Airaksinen, K.E. Juhani, additional, Opolski, Grzegorz, additional, Dworakowski, Rafal, additional, MacCarthy, Philip, additional, Kaiser, Christoph, additional, Osswald, Stefan, additional, Galiuto, Leonarda, additional, Crea, Filippo, additional, Dichtl, Wolfgang, additional, Empen, Klaus, additional, Felix, Stephan B., additional, Delmas, Clément, additional, Lairez, Olivier, additional, El-Battrawy, Ibrahim, additional, Akin, Ibrahim, additional, Borggrefe, Martin, additional, Horowitz, John, additional, Kozel, Martin, additional, Tousek, Petr, additional, Widimský, Petr, additional, Gilyarova, Ekaterina, additional, Shilova, Alexandra, additional, Gilyarov, Mikhail, additional, Winchester, David E., additional, Ukena, Christian, additional, Bax, Jeroen J., additional, Prasad, Abhiram, additional, Böhm, Michael, additional, Lüscher, Thomas F., additional, Ruschitzka, Frank, additional, and Templin, Christian, additional

Published
2018
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47. Long-Term Prognosis of Patients With Takotsubo Syndrome

Author

Ghadri, Jelena R., Kato, Ken, Cammann, Victoria L., Gili, Sebastiano, Jurisic, Stjepan, Di Vece, Davide, Candreva, Alessandro, Ding, Katharina J., Micek, Jozef, Szawan, Konrad A., Bacchi, Beatrice, Bianchi, Rahel, Levinson, Rena A., Wischnewsky, Manfred, Seifert, Burkhardt, Schlossbauer, Susanne A., Citro, Rodolfo, Bossone, Eduardo, Muenzel, Thomas, Knorr, Maike, Heiner, Susanne, D'Ascenzo, Fabrizio, Franke, Jennifer, Sarcon, Annahita, Napp, L. Christian, Jaguszewski, Milosz, Noutsias, Michel, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Tschoepe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Empen, Klaus, Felix, Stephan B., Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Horowitz, John, Kozel, Martin, Tousek, Petr, Widimsky, Petr, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Winchester, David E., Ukena, Christian, Bax, Jeroen J., Prasad, Abhiram, Boehm, Michael, Luscher, Thomas F., Ruschitzka, Frank, Templin, Christian, Ghadri, Jelena R., Kato, Ken, Cammann, Victoria L., Gili, Sebastiano, Jurisic, Stjepan, Di Vece, Davide, Candreva, Alessandro, Ding, Katharina J., Micek, Jozef, Szawan, Konrad A., Bacchi, Beatrice, Bianchi, Rahel, Levinson, Rena A., Wischnewsky, Manfred, Seifert, Burkhardt, Schlossbauer, Susanne A., Citro, Rodolfo, Bossone, Eduardo, Muenzel, Thomas, Knorr, Maike, Heiner, Susanne, D'Ascenzo, Fabrizio, Franke, Jennifer, Sarcon, Annahita, Napp, L. Christian, Jaguszewski, Milosz, Noutsias, Michel, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Tschoepe, Carsten, Pieske, Burkert M., Rajan, Lawrence, Michels, Guido, Pfister, Roman, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Banning, Adrian, Cuculi, Florim, Kobza, Richard, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Empen, Klaus, Felix, Stephan B., Delmas, Clement, Lairez, Olivier, El-Battrawy, Ibrahim, Akin, Ibrahim, Borggrefe, Martin, Horowitz, John, Kozel, Martin, Tousek, Petr, Widimsky, Petr, Gilyarova, Ekaterina, Shilova, Alexandra, Gilyarov, Mikhail, Winchester, David E., Ukena, Christian, Bax, Jeroen J., Prasad, Abhiram, Boehm, Michael, Luscher, Thomas F., Ruschitzka, Frank, and Templin, Christian

Abstract

BACKGROUND Prognosis of Takotsubo syndrome (TTS) remains controversial due to scarcity of available data. Additionally, the effect of the triggering factors remains elusive. OBJECTIVES This study compared prognosis between TTS and acute coronary syndrome (ACS) patients and investigated short- and long-term outcomes in TTS based on different triggers. METHODS Patients with TTS were enrolled from the International Takotsubo Registry. Long-term mortality of patients with TTS was compared to an age- and sex-matched cohort of patients with ACS. In addition, short- and long-term outcomes were compared between different groups according to triggering conditions. RESULTS Overall, TTS patients had a comparable long-term mortality risk with ACS patients. Of 1,613 TTS patients, an emotional trigger was detected in 485 patients (30%). Of 630 patients (39%) related to physical triggers, 98 patients (6%) had acute neurologic disorders, while in the other 532 patients (33%), physical activities, medical conditions, or procedures were the triggering conditions. The remaining 498 patients (31%) had no identifiable trigger. TTS patients related to physical stress showed higher mortality rates than ACS patients during long-term follow-up, whereas patients related to emotional stress had better outcomes compared with ACS patients. CONCLUSIONS Overall, TTS patients had long-term outcomes comparable to age- and sex-matched ACS patients. Also, we demonstrated that TTS can either be benign or a life-threating condition depending on the inciting stress factor. We propose a new classification based on triggers, which can serve as a clinical tool to predict short- and long-term outcomes of TTS. (C) 2018 by the American College of Cardiology Foundation.

Published
2018

49. Happy heart syndrome: role of positive emotional stress in takotsubo syndrome

Author

Ghadri, Jelena R., Sarcon, Annahita, Diekmann, Johanna, Bataiosu, Dana Roxana, Cammann, Victoria L., Jurisic, Stjepan, Napp, Lars Christian, Jaguszewski, Milosz, Scherff, Frank, Brugger, Peter, Jäncke, Lutz, Seifert, Burkhardt, Bax, Jeroen J., Ruschitzka, Frank, Lüscher, Thomas F., Templin, Christian, Schwyzer, Moritz, Franke, Jennifer, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Tschöpe, Carsten, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Ukena, Christian, Böhm, Michael, Erbel, Raimund, Cuneo, Alessandro, Kuck, Karl Heinz, Jacobshagen, Claudius, Hasenfuß, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun Dullaeus, Ruediger C., Cuculi, Florim, Banning, Adrian, Fischer, Thomas A., Vasankari, Tuija, Juhani Airaksinen, K. E., Fijalkowski, Marcin, Rynkiewicz, Andrzej, Opolski, Grzegorz, Dworakowski, Rafal, Maccarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Franz, Wolfgang M., Empen, Klaus, Felix, Stephan B., Delmas, Clément, Lairez, Olivier, Erne, Paul, Prasad, Abhiram, University of Zurich, and Templin, Christian

Subjects
Brain–heart connection, Medizin, heart failure, 030204 cardiovascular system & hematology, Anger, tako tsubo, Chest pain, Electrocardiography, 0302 clinical medicine, media_common, Broken heart syndrome, medicine.diagnostic_test, Brain-heart connection, 10093 Institute of Psychology, Heart Failure/Cardiomyopathy, Heart, Syndrome, Acute heart failure, Takotsubo syndrome, Cardiology and Cardiovascular Medicine, 10209 Clinic for Cardiology, Cardiology, medicine.symptom, Cardiomyopathies, medicine.medical_specialty, media_common.quotation_subject, 610 Medicine & health, UFSP13-4 Dynamics of Healthy Aging, 2705 Cardiology and Cardiovascular Medicine, 03 medical and health sciences, Clinical Research, Takotsubo Cardiomyopathy, Internal medicine, Post-hoc analysis, medicine, Humans, takotsubo syndrome, Psychiatry, business.industry, Stressor, 10060 Epidemiology, Biostatistics and Prevention Institute (EBPI), ta3121, medicine.disease, 10040 Clinic for Neurology, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, Happiness, Grief, business, 030217 neurology & neurosurgery, Stress, Psychological
Abstract

Aims Takotsubo syndrome (TTS) is typically provoked by negative stressors such as grief, anger, or fear leading to the popular term 'broken heart syndrome'. However, the role of positive emotions triggering TTS remains unclear. The aim of the present study was to analyse the prevalence and characteristics of patients with TTS following pleasant events, which are distinct from the stressful or undesirable episodes commonly triggering TTS. Methods and results Takotsubo syndrome patients with preceding pleasant events were compared to those with negative emotional triggers from the International Takotsubo Registry. Of 1750 TTS patients, we identified a total of 485 with a definite emotional trigger. Of these, 4.1% (n = 20) presented with pleasant preceding events and 95.9% (n = 465) with unequivocal negative emotional events associated with TTS. Interestingly, clinical presentation of patients with 'happy heart syndrome' was similar to those with the 'broken heart syndrome' including symptoms such as chest pain [89.5% (17/19) vs. 90.2% (412/457), P = 1.0]. Similarly, electrocardiographic parameters, laboratory findings, and 1-year outcome did not differ. However, in a post hoc analysis, a disproportionate higher prevalence of midventricular involvement was noted in 'happy hearts' compared with 'broken hearts' (35.0 vs. 16.3%, P = 0.030). Conclusion Our data illustrate that TTS can be triggered by not only negative but also positive life events. While patient characteristics were similar between groups, the midventricular TTS type was more prevalent among the 'happy hearts' than among the 'broken hearts'. Presumably, despite their distinct nature, happy and sad life events may share similar final common emotional pathways, which can ultimately trigger TTS. OA hybrid - CA extern

Published
2016

50. A novel clinical score (InterTAK Diagnostic Score) to differentiate takotsubo syndrome from acute coronary syndrome: results from the International Takotsubo Registry

Author

Ghadri, Jelena R., Cammann, Victoria L., Jurisic, Stjepan, Seifert, Burkhardt, Napp, L. Christian, Diekmann, Johanna, Bataiosu, Dana Roxana, D'Ascenzo, Fabrizio, Ding, Katharina J., Sarcon, Annahita, Kazemian, Elycia, Birri, Tanja, Ruschitzka, Frank, Luscher, Thomas F., Templin, Christian, Jaguszewski, Milosz, Franke, Jennifer, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Tschoepe, Carsten, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Ukena, Christian, Boehm, Michael, Erbel, Raimund, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Cuculi, Florim, Banning, Adrian, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Fijalkowski, Marcin, Rynkiewicz, Andrzej, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Franz, Wolfgang M., Empen, Klaus, Felix, Stephan B., Delmas, Clement, Lairez, Olivier, Erne, Paul, Frantz, Stefan, Prasad, Abhiram, Bax, Jeroen J., Ghadri, Jelena R., Cammann, Victoria L., Jurisic, Stjepan, Seifert, Burkhardt, Napp, L. Christian, Diekmann, Johanna, Bataiosu, Dana Roxana, D'Ascenzo, Fabrizio, Ding, Katharina J., Sarcon, Annahita, Kazemian, Elycia, Birri, Tanja, Ruschitzka, Frank, Luscher, Thomas F., Templin, Christian, Jaguszewski, Milosz, Franke, Jennifer, Katus, Hugo A., Burgdorf, Christof, Schunkert, Heribert, Thiele, Holger, Bauersachs, Johann, Tschoepe, Carsten, Rajan, Lawrence, Michels, Guido, Pfister, Roman, Ukena, Christian, Boehm, Michael, Erbel, Raimund, Cuneo, Alessandro, Jacobshagen, Claudius, Hasenfuss, Gerd, Karakas, Mahir, Koenig, Wolfgang, Rottbauer, Wolfgang, Said, Samir M., Braun-Dullaeus, Ruediger C., Cuculi, Florim, Banning, Adrian, Fischer, Thomas A., Vasankari, Tuija, Airaksinen, K. E. Juhani, Fijalkowski, Marcin, Rynkiewicz, Andrzej, Opolski, Grzegorz, Dworakowski, Rafal, MacCarthy, Philip, Kaiser, Christoph, Osswald, Stefan, Galiuto, Leonarda, Crea, Filippo, Dichtl, Wolfgang, Franz, Wolfgang M., Empen, Klaus, Felix, Stephan B., Delmas, Clement, Lairez, Olivier, Erne, Paul, Frantz, Stefan, Prasad, Abhiram, and Bax, Jeroen J.

Abstract

Aims Clinical presentation of takotsubo syndrome (TTS) mimics acute coronary syndrome (ACS) and does not allow differentiation. We aimed to develop a clinical score to estimate the probability of TTS and to distinguish TTS from ACS in the acute stage. Methods and results Patients with TTS were recruited from the International Takotsubo Registry (www.takotsubo-registry.com) and ACS patients from the leading hospital in Zurich. A multiple logistic regression for the presence of TTS was performed in a derivation cohort (TTS, n = 218; ACS, n = 436). The best model was selected and formed a score (InterTAK Diagnostic Score) with seven variables, and each was assigned a score value: female sex 25, emotional trigger 24, physical trigger 13, absence of ST-segment depression (except in lead aVR) 12, psychiatric disorders 11, neurologic disorders 9, and QTc prolongation 6 points. The area under the curve (AUC) for the resulting score was 0.971 [95% confidence interval (CI) 0.96-0.98] and using a cut-off value of 40 score points, sensitivity was 89% and specificity 91%. When patients with a score of >= 50 were diagnosed as TTS, nearly 95% of TTS patients were correctly diagnosed. When patients with a score <= 31 were diagnosed as ACS, similar to 95% of ACS patients were diagnosed correctly. The score was subsequently validated in an independent validation cohort (TTS, n = 173; ACS, n = 226), resulting in a score AUC of 0.901 (95% CI 0.87-0.93). Conclusion The InterTAK Diagnostic Score estimates the probability of the presence of TTS and is able to distinguish TTS from ACS with a high sensitivity and specificity.

Published
2017

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