136 results on '"Cundiff GW"'
Search Results
2. Foundation for an evidence-informed algorithm for treating pelvic floor mesh complications: a review
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Cundiff, GW, primary, Quinlan, DJ, additional, van Rensburg, JA, additional, and Slack, M, additional
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- 2018
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3. Authors' reply re: Perinatal and maternal morbidity and mortality among term singletons following midcavity operative vaginal delivery versus caesarean delivery
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Muraca, GM, primary, Skoll, A, additional, Lisonkova, S, additional, Sabr, Y, additional, Brant, R, additional, Cundiff, GW, additional, and Joseph, KS, additional
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- 2017
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4. Perinatal and maternal morbidity and mortality among term singletons following midcavity operative vaginal delivery versus caesarean delivery
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Muraca, GM, primary, Skoll, A, additional, Lisonkova, S, additional, Sabr, Y, additional, Brant, R, additional, Cundiff, GW, additional, and Joseph, KS, additional
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- 2017
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5. Risk factors for anal sphincter tear during vaginal delivery.
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Fitzgerald MP, Weber AM, Howden N, Cundiff GW, Brown MB, and Pelvic Floor Disorders Network
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- 2007
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6. Abdominal sacrocolpopexy with Burch colposuspension to reduce urinary stress incontinence.
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Brubaker L, Cundiff GW, Fine P, Nygaard I, Richter HE, Visco AG, Zyczynski H, Brown MB, Weber AM, Pelvic Floor Disorders Network, Brubaker, Linda, Cundiff, Geoffrey W, Fine, Paul, Nygaard, Ingrid, Richter, Holly E, Visco, Anthony G, Zyczynski, Halina, Brown, Morton B, and Weber, Anne M
- Abstract
Background: We designed this trial to assess whether the addition of standardized Burch colposuspension to abdominal sacrocolpopexy for the treatment of pelvic-organ prolapse decreases postoperative stress urinary incontinence in women without preoperative symptoms of stress incontinence.Methods: Women who did not report symptoms of stress incontinence and who chose to undergo sacrocolpopexy to treat prolapse were randomly assigned to concomitant Burch colposuspension or to no Burch colposuspension (control) and were evaluated in a blinded fashion three months after the surgery. The primary outcomes included measures of stress incontinence (symptoms, stress testing, or treatment) and measures of urge symptoms. Enrollment was stopped after the first interim analysis because of a significantly lower frequency of stress incontinence in the group that underwent the Burch colposuspension.Results: Of 322 women who underwent randomization, 157 were assigned to Burch colposuspension and 165 to the control group. Three months after surgery, 33.6 percent of the women in the Burch group and 57.4 percent of the controls met one or more of the criteria for stress incontinence (P<0.001) [Corrected]. There was no significant difference between the Burch group and the control group in the frequency of urge incontinence (32.7 percent vs. 38.4 percent, P=0.48). After surgery, women in the control group were more likely to report bothersome symptoms of stress incontinence than those in the Burch group who had stress incontinence (24.5 percent vs. 6.1 percent, P<0.001).Conclusions: In women without stress incontinence who are undergoing abdominal sacrocolpopexy for prolapse, Burch colposuspension significantly reduced postoperative symptoms of stress incontinence without increasing other lower urinary tract symptoms. [ABSTRACT FROM AUTHOR]- Published
- 2006
7. Evaluation and treatment of women with rectocele: focus on associated defecatory and sexual dysfunction.
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Cundiff GW and Fenner D
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- 2004
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8. A survey of pessary use by members of the American urogynecologic society.
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Cundiff GW, Weidner AC, Visco AG, Bump RC, Addison WA, Cundiff, G W, Weidner, A C, Visco, A G, Bump, R C, and Addison, W A
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- 2000
9. Graduate education. Analysis of the effectiveness of an endoscopy education program in improving residents' laparoscopic skills.
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Cundiff GW
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- 1997
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10. Vaginal Uncomplicated Delivery Rate as a Quality Indicator Compared to Cesarean Delivery Rate: A Quantitative Analysis of a Population Database.
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Cundiff GW, Kaur P, Hanley GE, and Janssen P
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Objectives: The objective of this study is to compare the vaginal uncomplicated delivery (VUD) rate, defined as all vaginal deliveries (including forceps and vacuum) without an adverse maternal or neonatal labour outcome, to the cesarean delivery (CD) rate, as a performance indicator., Methods: This is a retrospective cohort analysis from a provincial database of all term deliveries by an obstetrician in a single year, excluding diagnoses preventing active labour. Most obstetricians in this jurisdiction practice consultative obstetrics, focused on supporting primary maternity care. We investigated the association of adverse delivery (AD), measured by the adverse outcome index, with CD and VUD rates., Results: We report 16 620 deliveries by 210 obstetricians, with a vaginal delivery rate of 39.6%, of which 36.6% were operative vaginal delivery. The overall AD rate was 9.9%, and the overall VUD rate was 34%. While the CD and VUD both correlated with the mode of delivery, only the VUD rate was correlated to the AD rate., Conclusions: Quality assurance in obstetrics must balance the needs of 2 patients based on limited data. Our data shows the shortcomings of the prevailing performance indicator, CD rate, which does not correlate with birth outcomes for the pregnant patient or infant. The VUD rate provides an alternative that assesses both mode of delivery and labour outcomes. Shifting the quality lens to focus on the VUD rate will provide a better metric that measures optimal outcomes for pregnant people and their babies., (Copyright © 2024 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.)
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- 2024
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11. Procedure-specific simulation for vaginal surgery training: A randomized controlled trial.
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Geoffrion R, Koenig NA, Cundiff GW, Flood C, Hyakutake MT, Schulz J, Brennand EA, Lee T, Singer J, and Todd NJ
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- Humans, Female, Adult, Hysterectomy, Vaginal education, Male, Gynecologic Surgical Procedures education, Gynecology education, Clinical Competence, Internship and Residency, Simulation Training methods, Vagina surgery
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Introduction: Vaginal surgery has a superior outcome profile compared with other surgical routes, yet skills are declining because of low case volumes. Graduating residents' confidence and preparedness for vaginal surgery has plummeted in the past decade. The objective of the present study was to investigate whether procedure-specific simulation skills, vs usual training, result in improved operative competence., Material and Methods: We completed a randomized controlled trial of didactic and procedural training via low fidelity vaginal surgery models for anterior repair, posterior repair (PR), vaginal hysterectomy (VH), recruiting novice gynecology residents at three academic centers. We evaluated performance via global rating scale (GRS) in the real operating room and for corresponding procedures by attending surgeon blinded to group. Prespecified secondary outcomes included procedural steps knowledge, overall performance, satisfaction, self-confidence and intraoperative parameters. A priori sample size estimated 50 residents (20% absolute difference in GRS score, 25% SD, 80% power, alpha 0.05)., Clinicaltrials: gov: Registration no. NCT05887570., Results: We randomized 83 residents to intervention or control and 55 completed the trial (2011-23). Baseline characteristics were similar, except for more fourth-year control residents. After adjustment of confounders (age, level, baseline knowledge), GRS scores showed significant differences overall (mean difference 8.2; 95% confidence interval [CI]: 0.2-16.1; p = 0.044) and for VH (mean difference 12.0; 95% CI: 1.8-22.3; p = 0.02). The intervention group had significantly higher procedural steps knowledge and self-confidence for VH and/or PR (p < 0.05, adjusted analysis). Estimated blood loss, operative time and complications were similar between groups., Conclusions: Compared to usual training, procedure-specific didactic and low fidelity simulation modules for vaginal surgery resulted in significant improvements in operative performance and several other skill parameters., (© 2024 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).)
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- 2024
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12. Pilot Study of a Digital Behavioral Therapy for Overactive Bladder in Women.
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Sooknarine C, Farrell S, Sarma S, Salameh F, Burke N, Staunton B, Carr E, Sexton K, Agnew G, Downey A, D'Arcy F, and Cundiff GW
- Abstract
Importance: The burden and high prevalence of overactive bladder (OAB) underline the urgent need for effective treatment. This study provides an initial look at an alternative approach to behavioral therapy for overactive bladder (OAB) that is delivered as an app on a smartphone., Objective: This study aimed to investigate feasibility, acceptability, and preliminary efficacy of a digital therapeutic for OAB., Study Design: This was a multicentered prospective pilot study. We used a convenience sample (N = 30) from waiting lists of women referred for incontinence, excluding urinary tract infections, urinary retention, bladder pain syndrome, pelvic cancer, current pregnancy, kidney disease, dementia, stroke, and prior neuromodulation. The intervention, a smartphone app, provided an 8-week program with weekly modules combining evidence-based knowledge videos and skill-building exercises that incorporated behavioral therapy, cognitive behavioral therapy, pelvic muscle training, and general health information. Combined scores on the International Consultation on Incontinence Questionnaire was the primary outcome measure. Secondary outcomes included improvement in quality of life, based on International Consultation on Incontinence Questionnaire, a 72-hour urinary diary, and Patient Global Impression of Improvement. We evaluated usability with the Mobile Application Rating Scale. Statistical tests included Shapiro-Wilk tests and paired-sample t tests., Results: Overall, 100% of participants reported a reduction in their OAB symptoms and 82% reported an improvement in quality of life. There was a significant improvement in diary parameters, including frequency (10.19-6.71 a day: SD, 1.25; P = 0.017) and incontinence (10-3.57: SD, 4.58). Participants rated the app highly on functionality, and 70% would recommend it. Patient Global Impression of Improvement improved for 72% of participants., Conclusions: This study supports the application of a digital platform to over-come the real-world barriers for first-line treatment for OAB and offers information to inform further evaluation of the safety and efficacy of the NUIG OAB App., (Copyright © 2024 American Urogynecologic Society. All rights reserved.)
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- 2024
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13. A Longitudinal Assessment of a Physician Performance Enhancement Program Using Health Data, to Improve Quality of Care and Facilitate Lifelong Learning.
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Cundiff GW, Chan V, and Luo J
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- Female, Humans, Pregnancy, Benchmarking, Retrospective Studies, Surveys and Questionnaires, Education, Continuing, Physicians, Clinical Competence
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The Personal Quality Index (PQI) provides individual annual reports of benchmarked clinical data to inform practice development. This 5-year longitudinal retrospective study of PQI performance indicators also surveyed department members (n = 104) on utility, using t test, and Wilcoxon test. Technicity increased from 59% in 2014 to 72% in 2018 (P < 0.001). The vaginal birth after cesarean delivery rate did not improve, but the combined forceps/vacuum delivery rate decreased for sites and physicians (P < 0.001). Survey response was 35%. Most physicians (62%) found it valuable, and it informed professional development in 23% of cases. Nevertheless, 42% did not trust the data, and 39% found the process provoked anxiety., (Copyright © 2023 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.)
- Published
- 2023
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14. Performance of Perioperative Tasks for Women Undergoing Anti-incontinence Surgery: Developed by the AUGS Quality Improvement and Outcomes Research Network.
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Erekson E, Whitcomb EL, Kamdar N, Swift S, Cundiff GW, Yaklic J, Strohbehn K, Adam R, Danford J, Willis-Gray MG, Maxwell R, Edenfield A, Pulliam S, Gong M, Malek M, Hanissian P, Towers G, Guaderrama NM, Slocum P, and Morgan D
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- Humans, Female, Outcome Assessment, Health Care, Urinary Incontinence, Stress surgery
- Abstract
Objectives: Surgery for the correction of stress urinary incontinence is an elective procedure that can have a dramatic and positive impact on quality of life. Anti-incontinence procedures, like inguinal hernia repairs or cholecystectomies, can be classified as high-volume/low-morbidity procedures. The performance of a standard set of perioperative tasks has been suggested as one way to optimize quality of care in elective high-volume/low-morbidity procedures. Our primary objective was to evaluate the performance of 5 perioperative tasks-(1) offering nonsurgical treatment, (2) performance of a standard preoperative prolapse examination, (3) cough stress test, (4) postvoid residual test, and (5) intraoperative cystoscopy for women undergoing surgery for stress urinary incontinence-compared among surgeons with and without board certification in female pelvic medicine and reconstructive surgery (FPMRS)., Study Design: This study was a retrospective chart review of anti-incontinence surgical procedures performed between 2011 and 2013 at 9 health systems. Cases were reviewed for surgical volume, adverse outcomes, and the performance of 5 perioperative tasks and compared between surgeons with and without FPMRS certification., Results: Non-FPMRS surgeons performed fewer anti-incontinence procedures than FPMRS-certified surgeons. Female pelvic medicine and reconstructive surgery surgeons were more likely to perform all 5 perioperative tasks compared with non-FPMRS surgeons. After propensity matching, FPMRS surgeons had fewer patients readmitted within 30 days of surgery compared with non-FPMRS surgeons., Conclusions: Female pelvic medicine and reconstructive surgery surgeons performed higher volumes of anti-incontinence procedures, were more likely to document the performance of the 5 perioperative tasks, and were less likely to have their patients readmitted within 30 days., (Copyright © 2023 American Urogynecologic Society. All rights reserved.)
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- 2023
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15. Surgical sexism in Canada: structural bias in reimbursement of surgical care for women.
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Chaikof M, Cundiff GW, Mohtashami F, Millman A, Larouche M, Pierce M, Brennand EA, and McDermott C
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- Pregnancy, Humans, Male, Female, Canada, Sexism, Surgeons
- Abstract
Background: It is well established that female physicians in Canada are reimbursed at lower rates than their male counterparts. To explore if a similar discrepancy exists in reimbursement for care provided to female and male patients, we addressed this question: Do Canadian provincial health insurers reimburse physicians at lower rates for surgical care provided to female patients than for similar care provided to male patients?, Methods: Using a modified Delphi process, we generated a list of procedures performed on female patients, which we paired with equivalent procedures performed on male patients. We then collected data from provincial fee schedules for comparison., Results: In 8 out of 11 Canadian provinces and territories studied, we found that surgeons were reimbursed at significantly lower rates (28.1% [standard deviation 11.1%]) for procedures performed on female patients than for similar procedures performed on male patients., Conclusion: The lower reimbursement of the surgical care of female patients than for similar care provided to male patients represents double discrimination against both female physicians and their female patients, as female providers predominate in obstetrics and gynecology. We hope our analysis will catalyze recognition and meaningful change to address this systematic inequity, which both disadvantages female physicians and threatens the quality of care for Canadian women., Competing Interests: Competing interests: G. Cundiff has received book royalties from Wolters Kluwer and honoraria from AbbVie. He is the chief medical officer for Amara Therapeutics and has a patent pending with this company. F. Mohtashami has received educational grants from Medtronic, Hologic and Boston Scientific. E. Brennand has received speaking fees from Searchlight Pharma. C. McDermott is a medical advisor for Szio+ and COSM and has stocks or stock options in these companies. She is also a speaker for Pfizer., (© 2023 CMA Impact Inc. or its licensors.)
- Published
- 2023
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16. Does AUGS Still Have Quality Assurance Goals?
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Cundiff GW
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- 2023
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17. Symptom and Anatomical Phenotypes Provide Insights Into Interactions of Prolapse Symptoms and Anatomy.
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Fong A, Talhouk A, Chiu D, Koenig N, and Cundiff GW
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- Humans, Female, Pelvic Floor Disorders complications, Urinary Incontinence, Stress complications, Pelvic Organ Prolapse epidemiology
- Abstract
Importance: Women pursue treatment to relieve symptoms, while surgeons repair anatomy, underlining the importance of the relationship between symptoms and anatomy., Objective: We hypothesized different anatomical and symptom phenotypes associated with pelvic organ prolapse (POP). Our objective was to investigate prevalence of phenotypes to explore associations of symptoms with anatomical defects., Methods: We defined 420 anatomical phenotypes from combinations of POP Quantification parameters and 128 symptom phenotypes from symptoms described by condition-specific questionnaires (Pelvic Floor Disorders Inventory, Short Form of the Personal Experience Questionnaire). We applied these to an anonymized database of 719 subjects with symptomatic pelvic floor disorders. Bar graphs were used to illustrate the distribution of anatomical and symptom phenotypes, as well as anatomical phenotypes of patients with specific symptoms. We then used biclustering analysis with the multiple latent block model, to identify patterns of clustered groups of subjects and features., Results: The most common symptom phenotypes have multiple (3-5) symptoms. A third of the theoretical anatomical phenotypes existed in our cohort. Bar graphs for specific symptom composites demonstrated unique distributions of anatomical phenotypes suggesting associations between anatomy and symptoms. Biclustering converged on 2 subject clusters (C1, C2) and 8 feature clusters. Cluster 1 (68%) represented a younger subpopulation with lower stage POP, more stress urinary incontinence and sexual dysfunction (P < 0.001 all). Cluster 2 had more protrusion (P < 0.001) and obstructed voiding (P = 0.001). Features that clustered together, such as stress urinary incontinence and sexual dysfunction, may represent underlying relationships., Conclusions: We demonstrated a relationship between locations of anatomical POP and certain symptoms, which may generate new hypotheses and guide clinical decision making., Competing Interests: The authors have declared they have no conflicts of interest., (Copyright © 2023 American Urogynecologic Society. All rights reserved.)
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- 2023
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18. Labor and delivery outcomes by delivery method in term deliveries in occiput posterior position: a population-based retrospective cohort study.
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Foggin HH, Albert AY, Minielly NC, Lisonkova S, Koenig NA, Jacobs EN, and Cundiff GW
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Background: Occiput posterior is the most common malposition in labor. Deliveries in occiput posterior position have been shown to have higher rates of adverse short-term maternal and neonatal outcomes compared with deliveries in occiput anterior position. There are no guidelines providing recommendations nor summarizing risks of adverse outcomes by delivery method to inform the decision-making process in occiput posterior delivery management. Population-based studies examining the outcomes associated with various management processes of occiput posterior position at the time of labor or delivery are lacking., Objective: This study aimed to describe the current management of term singleton occiput posterior deliveries in British Columbia, Canada and to examine the association between different management strategies and adverse outcomes by describing the rates of: occiput posterior malposition; and spontaneous vaginal delivery, operative vaginal delivery, and cesarean delivery from occiput posterior malposition. We also analyzed the rates of adverse labor and delivery outcomes stratified by fetal position and delivery mode, and the interaction effect of occiput posterior position and delivery mode on the rates of adverse outcomes., Study Design: This was a retrospective cohort study of cephalic term singleton deliveries in British Columbia from 2004 to 2020, using the British Columbia Perinatal Data Registry. The obstetrical adverse outcome index (a composite of 10 adverse maternal or neonatal events), adverse outcome index subcomponent rates, and adverse outcome index-derived weighted scores were compared between deliveries stratified by fetal position at delivery (occiput posterior or occiput anterior) and occiput posterior deliveries stratified by delivery method. Multivariable log-binomial logistic regression was used to model the adverse outcome index score., Results: Of 306,237 term births, 19% had occiput posterior position during labor, 37% of which persisted in occiput posterior position at delivery. Among occiput posterior deliveries, 27% were spontaneous vaginal deliveries, 8% vacuum, 5% forceps, 1% mixed vacuum-forceps, and 59% were cesarean delivery; this distribution differed from that of occiput anterior deliveries ( P <.0001). Overall, adverse outcome index scores were significantly higher in persistent occiput posterior deliveries (8.8% had ≥1 adverse outcomes; adjusted rate ratio, 1.07 [1.01-1.14]) than in occiput posterior labors that rotated to occiput anterior deliveries; the most frequent adverse outcome was third- or fourth-degree lacerations. Neonatal adverse outcomes were also more frequent in occiput posterior delivery (4.3% vs 3.3%; adjusted rate ratio, 1.21 [1.10-1.35]), whereas maternal outcomes were similar between groups (4.8% vs 6.0%; adjusted rate ratio, 1.04 [0.96-1.13]). Among persistent occiput posterior deliveries, spontaneous vaginal delivery and cesarean delivery had the lowest proportion of deliveries with ≥1 adverse outcomes (6.1% and 6.2%), whereas forceps deliveries had the highest (38.1%); the largest contributor to the adverse outcomes were third- or fourth-degree lacerations. Among occiput posterior deliveries with any adverse outcome, cesarean delivery had the highest Severity Index score, due in part to the inclusion of third- or fourth-degree tears (which are assigned a comparatively low score) as the most common adverse event in the other vaginal delivery modes, and because of outcomes with a higher severity score being associated with cesarean delivery, such as uterine rupture (a reason for cesarean delivery) and intensive care unit admission (an outcome following cesarean delivery). Overall, in a multivariable regression model, delivery mode and the interaction between delivery mode and occiput posterior position were significant predictors of a delivery with ≥1 adverse outcomes, whereas occiput posterior position itself was not., Conclusion: One in five singleton deliveries at term gestation had occiput posterior position in labor; most of these rotated to occiput anterior by delivery, which had better outcomes than persistent occiput posterior deliveries. Among the latter, spontaneous vaginal delivery and cesarean delivery had the lowest frequency of adverse outcomes, whereas forceps deliveries had the highest. This study provides a robust updated analysis of birth outcomes following different occiput posterior management strategies, which can inform provider decision-making and counseling. Its observational design may limit its use for direct recommendations for management of occiput posterior malposition, yet the study helps to define the risks associated with different modes of delivery in the setting of occiput posterior malposition. With additional studies examining success rates of intermediate occiput posterior-occiput anterior rotation, other delivery management steps, and long-term outcomes, this study helps to define safe management of occiput posterior delivery., (© 2022 The Authors.)
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- 2022
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19. Long-Term Outcomes After Vaginal and Laparoscopic Mesh Hysteropexy for Uterovaginal Prolapse: A Parallel Cohort Study (eVAULT).
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Fitzgerald JJ, Sokol ER, Rardin CR, Cundiff GW, Paraiso MFR, Chou J, and Gutman RE
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- Cohort Studies, Female, Gynecologic Surgical Procedures, Humans, Prospective Studies, Surgical Mesh adverse effects, Treatment Outcome, Laparoscopy adverse effects, Pelvic Organ Prolapse surgery, Uterine Prolapse surgery
- Abstract
Importance: Data on long-term mesh hysteropexy outcomes are limited. This study provides 7-year data from the original VAULT (Vaginal and Laparoscopic Mesh Hysteropexy for Uterovaginal Prolapse Trial) study., Objective: The aim of this study was to compare long-term outcomes and success for laparoscopic sacral hysteropexy (LSHP) and vaginal mesh hysteropexy (VMHP)., Study Design: This multicenter, prospective parallel cohort was an extension to the initial VAULT study. Subjects were contacted, and informed consent was obtained. We collected baseline demographics and the latest Pelvic Organ Prolapse-Quantification examination data from chart review and conducted telephone interviews to update demographic information and collect Pelvic Floor Distress Inventory Short-Form, Patient Global Impression of Improvement, prolapse reoperation/pessary use, and complications. Surgical success was defined as no bulge symptoms, satisfaction score of "very much better" or "much better," and no reoperation/pessary use., Results: Five of 8 original sites enrolled 53 subjects (LSHP n = 34 and VMHP n = 19). The LSHP group was younger (67 vs 74, P < 0.01), but there were no differences in parity, body mass index, menopause, race, insurance, tobacco use, or Charlson Comorbidity Index. The median subjective follow-up was 7.3 ± 0.9 years. Composite success was 82% LSHP versus 74% VMHP. Pelvic Floor Distress Inventory Short-Form composite scores were similar at baseline and improved for both groups (P < 0.01) with lower bother observed in the LSHP group (20.8 vs 43.8, P = 0.01). There were no differences in complications., Conclusions: Over 7 years after surgery, LSHP and VMHP have high success, low retreatment, and low complication rates that did not differ between groups. Although there is a trend toward better anatomic support in the LSHP group, these findings were not significant and we are underpowered to detect a difference., (Copyright © 2022 American Urogynecologic Society. All rights reserved.)
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- 2022
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20. Corrigendum to 'Canadian Society of Pelvic Medicine Response to the Collège des Médecins du Québec Rapport d'Enquête' [Journal of Obstetrics and Gynaecology Canada 43/3 (2021) 298-299].
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Walter JE, Brennand EA, Lemos N, and Cundiff GW
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- 2021
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21. Technicity in Canada: A Nationwide Whole-Population Analysis of Temporal Trends and Variation in Minimally Invasive Hysterectomies.
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Chen I, Mallick R, Allaire C, Bajzak KI, Belland LM, Bougie O, Cassell KA, Choudhry AJ, Cundiff GW, Kroft J, Leyland NA, Maheux-Lacroix S, Rajakumar C, Randle E, Robertson D, Thiel JA, Tulandi T, Yong PJ, and Laberge PY
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- British Columbia, Female, Humans, Hysterectomy, Vaginal adverse effects, Ontario, Retrospective Studies, Hysterectomy adverse effects, Laparoscopy
- Abstract
Study Objective: The objective of our study was to provide a contemporary description of hysterectomy practice and temporal trends in Canada., Design: A national whole-population retrospective analysis of data from the Canadian Institute for Health Information., Setting: Canada., Patients: All women who underwent hysterectomy for benign indication from April 1, 2007, to March 31, 2017, in Canada., Interventions: Hysterectomy., Measurements and Main Results: A total of 369 520 hysterectomies were performed in Canada during the 10-year period, during which the hysterectomy rate decreased from 313 to 243 per 100 000 women. The proportion of abdominal hysterectomies decreased (59.5% to 36.9%), laparoscopic hysterectomies increased (10.8% to 38.6%), and vaginal hysterectomies decreased (29.7% to 24.5%), whereas the national technicity index increased from 40.5% to 63.1% (p <.001, all trends). The median length of stay decreased from 3 (interquartile range 2-4) days to 2 (interquartile range 1-3), and the proportion of patients discharged within 24 hours increased from 2.1% to 7.2%. In year 2016-17, women aged 40 to 49 years had significantly increased risk of abdominal hysterectomy compared with women undergoing hysterectomy in other age categories (p <.001). Comparing women with menstrual bleeding disorders, women undergoing hysterectomy for endometriosis (adjusted relative risk [aRR] 1.36; 95% confidence interval [CI], 1.28-1.44) and myomas (aRR 2.01; 95% CI, 1.94-2.08) were at increased risk of abdominal hysterectomy, whereas women undergoing hysterectomy for pelvic organ prolapse and pelvic pain (aRR 1.47; 95% CI, 1.41-1.53) were at decreased risk. Using Ontario as the comparator, Nova Scotia (aRR 1.35; 95% CI, 1.27-1.43), New Brunswick (aRR 1.25; 95% CI, 1.18-1.32]), Manitoba (aRR 1.35; 95% CI, 1.28-1.43), and Newfoundland and Labrador (aRR 1.18; 95% CI, 1.10-1.27) had significantly higher risks of abdominal hysterectomy. In contrast, Saskatchewan (aRR 0.75; 95% CI, 0.74-0.77) and British Columbia (aRR 0.86; 95% CI, 0.85-0.88) had significantly lower risks, whereas Prince Edward Island, Quebec, and Alberta were not significantly different., Conclusion: The proportion of minimally invasive hysterectomies for benign indication has increased significantly in Canada. The declining use of vaginal approaches and the variation among provinces are of concern and necessitate further study., (Copyright © 2021 AAGL. All rights reserved.)
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- 2021
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22. Le Collège des médecins du Québec devrait-il déterminer l'utilisation adéquate des bandelettes sous-urétrales au Canada? Une analyse du rapport d'enquête.
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Cundiff GW
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- 2021
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23. Should the Collège des Médecins du Québec Determine How Mid-Urethral Slings Are Used in Canada? A Review of the Rapport d'Enquête.
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Cundiff GW
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- Canada, Female, Humans, Quebec, Suburethral Slings, Urinary Incontinence, Stress
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- 2021
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24. Letter: Canadian Society of Pelvic Medicine Response to the Collège des Médecins du Québec Rapport d'Enquête.
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Walter JE, Brennand EA, Lemos N, and Cundiff GW
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- Canada, Female, Humans, Quebec, Suburethral Slings, Urinary Incontinence, Stress
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- 2021
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25. Urinary symptoms and quality of life in women living with HIV: a cross-sectional study.
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Larouche M, Albert AYK, Lipsky N, Walmsley S, Loutfy M, Smaill F, Trottier S, Bitnun A, Yudin MH, Cundiff GW, and Money DM
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- Adult, Canada, Cross-Sectional Studies, Female, Humans, Prospective Studies, Surveys and Questionnaires, HIV Infections complications, Quality of Life
- Abstract
Introduction and Hypothesis: To determine prevalence and quality of life impact of lower urinary tract symptoms (LUTS) in women living with HIV (WLWH)., Methods: Cross-sectional urinary questionnaires were included in a multicenter national prospective study of the HPV vaccine in WLWH. Demographic and clinical information was abstracted from the parent study. The Urinary Distress Inventory (UDI-6) and Urinary Impact Questionnaire (UIQ-7) were administered. Wilcoxon rank sum, two-sample chi-square or Fisher's exact tests were used as appropriate to compare women with UDI-6 score ≥ 25 to those with lower UDI-6 scores on demographic and HIV-related factors. Significant categorical variables were followed up with logistic regression to estimate odds ratios (OR)., Results: One hundred seventy-seven women completed urinary questionnaires (85.5% of cohort). Median age was 44.1 (37.2-50.6). Mean CD4 count was 621 (410-785), and 132 women (74.6%) were virologically suppressed. Median UDI-6 score was 4.2 (0-25). Fifty-one women (28.8%) had a UIQ-7 score > 0. Among those with a UDI-6 score of at least 25, median UIQ-7 was 9.5 (0-47.6). UDI-6 ≥ 25 was significantly associated with increasing age, higher BMI, Canada as country of origin, peri-/postmenopausal status (OR 3.37, 95% CI = 1.71 to 6.75) and being parous (OR 2.92, 95% CI = 1.27 to 7.59) (all p < 0.05). HIV-related factors were not associated with UDI-6 ≥ 25., Conclusions: LUTS were common, but we did not demonstrate a negative impact on quality of life in this sample of WLWH. Large comparative studies are needed to determine whether HIV is a risk factor for bothersome LUTS in women.
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- 2021
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26. Regional Variation and Temporal Trends in Surgery for Pelvic Organ Prolapse in Canada, 2004-2014.
- Author
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Lisonkova S, Geoffrion R, Sanaee M, Muraca GM, Wen Q, Yong PJ, Larouche M, and Cundiff GW
- Subjects
- Adult, Aged, Aged, 80 and over, Canada epidemiology, Cross-Sectional Studies, Female, Gynecologic Surgical Procedures statistics & numerical data, Humans, Middle Aged, Pelvic Organ Prolapse epidemiology, Quebec, Surgical Mesh, Treatment Outcome, Vagina, Gynecologic Surgical Procedures trends, Pelvic Organ Prolapse surgery
- Abstract
Objectives: We sought to examine temporal trends in pelvic organ prolapse (POP) surgery in Canada., Methods: In this observational cross-sectional study, we used diagnostic and procedure codes from all hospitalizations and outpatient clinic visits in Canada (excluding Québec) from 2004 to 2014 to identify and analyze data on POP surgery., Results: There were 204 301 POP surgery visits from 2004 to 2014, and the rate of POP surgery declined from 19.3 to 16.0 per 10 000 women during this period. The rates of "native tissue reconstructive repair" and "hysterectomy without other procedure" declined from 15.0 to 12.8 per 10 000 women and 2.6 to 1.6 per 10 000 women, respectively. The rate of obliteration increased from 0.1 to 0.3 per 10 000 women (all P values for trend <0.01). Mesh procedures increased from 1.6 per 10 000 women in 2004 to 2.4 per 10 000 women in 2007 and 2008, and then declined to 1.3 per 10 000 women in 2014. Reconstructive mesh surgery using an abdominal open approach declined, while laparoscopic procedures increased over the period examined., Conclusion: The rates of POP surgery declined in Canada between 2004 and 2014. An increase was observed in obliteration procedures and in laparoscopic vaginal suspension and fixation with mesh., (Copyright © 2020 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.)
- Published
- 2020
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27. In pursuit of patient-centered innovation: The role of professional organizations.
- Author
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Thakar R and Cundiff GW
- Subjects
- Humans, Patient-Centered Care, Societies
- Published
- 2020
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28. Depression, Anxiety, and Pelvic Floor Symptoms Before and After Surgery for Pelvic Floor Dysfunction.
- Author
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Larouche M, Brotto LA, Koenig NA, Lee T, Cundiff GW, and Geoffrion R
- Subjects
- Aged, Anxiety complications, Causality, Depression complications, Female, Humans, Middle Aged, Pain, Postoperative complications, Patient Reported Outcome Measures, Pelvic Organ Prolapse surgery, Postoperative Period, Preoperative Period, Prospective Studies, Quality of Life, Anxiety psychology, Depression psychology, Pain, Postoperative psychology, Pelvic Organ Prolapse psychology
- Abstract
Objectives: We aimed to explore the correlation between perioperative symptoms of depression and anxiety with pelvic floor symptoms after urogynecologic surgery. Postoperative pain, goal attainment, quality of life, and satisfaction were assessed., Methods: A prospective cohort study of women undergoing inpatient urogynecologic surgery was conducted. Preoperative questionnaires included Beck Depression and Beck Anxiety Inventories, Pain Catastrophizing Scale, Pelvic Floor Distress Inventory, Pelvic Floor Impact Questionnaire, and a detailed goals and perioperative supports questionnaire. Postoperative pain was assessed via the Short-Form McGill Pain Questionnaire. Questionnaires were readministered 6 weeks postoperatively. Descriptive statistics were obtained. Spearman correlation determined the relationship between preoperative and postoperative questionnaire scores. Quantile regression assessed the potential moderating effect of patient characteristics on these relationships., Results: Sixty women (mean age, 58.5 years) were recruited. Fifty-seven (95%) completed follow-up. Most common surgical indication was pelvic organ prolapse (59/60; 98%). Depression and anxiety symptoms were minimal in most women. There was significant median change in preoperative to postoperative scores for Beck Anxiety Inventory (-2.0, P = 0.011), Pelvic Floor Distress Inventory-20 (-69.4, P < 0.001), and Pelvic Floor Impact Questionnaire-7 (-23.8, P = 0.001). Baseline depression and anxiety symptoms were correlated with higher immediate postoperative pain, but not other outcomes. The most common goal, achieved by 47 (92%) of 51, was to reduce condition-specific symptoms. Postoperative depression and anxiety symptoms, and pelvic floor distress and impact were significantly correlated., Conclusions: Baseline depression and anxiety symptoms were not significantly associated with postoperative pelvic floor symptom burden or surgical satisfaction. Bothersome postoperative pelvic floor symptoms were associated with postoperative depressive symptoms.
- Published
- 2020
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29. Episiotomy use among vaginal deliveries and the association with anal sphincter injury: a population-based retrospective cohort study.
- Author
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Muraca GM, Liu S, Sabr Y, Lisonkova S, Skoll A, Brant R, Cundiff GW, Stephansson O, Razaz N, and Joseph KS
- Subjects
- Adult, Female, Follow-Up Studies, Humans, Incidence, Infant, Newborn, Pregnancy, Quebec epidemiology, Retrospective Studies, Risk Factors, Anal Canal injuries, Delivery, Obstetric methods, Episiotomy statistics & numerical data, Obstetric Labor Complications epidemiology, Population Surveillance methods
- Abstract
Background: The rate of obstetric anal sphincter injury has increased in recent years, particularly among operative vaginal deliveries. We sought to characterize temporal trends in episiotomy use and to quantify the association between episiotomy and obstetric anal sphincter injury., Methods: Using a population-based retrospective cohort study design of hospital data from 2004 to 2017, we studied all vaginal deliveries of singleton infants at term gestation in Canada (excluding Quebec). Rates of obstetric anal sphincter injury were contrasted between women who had an episiotomy and those who did not. Log-binomial regression was used to estimate the association between episiotomy and obstetric anal sphincter injury among women with spontaneous and operative vaginal deliveries after controlling for confounders., Results: The study population included 2 570 847 deliveries. Episiotomy use declined significantly among operative vaginal deliveries (53.1% in 2004 to 43.2% in 2017, p < 0.0001) and spontaneous vaginal deliveries (13.5% in 2004 to 6.5% in 2017, p < 0.0001). Episiotomy was associated with higher rates of obstetric anal sphincter injury among spontaneous vaginal deliveries (4.8 with episiotomy v. 2.4% without; adjusted rate ratio [RR] 2.06, 95% confidence interval [CI] 2.00-2.11) and this association remained after stratification by parity and obstetric history. In contrast, episiotomy was associated with lower rates of obstetric anal sphincter injury among forceps deliveries in nulliparous women (adjusted RR 0.63, 95% CI 0.61-0.66), and women with vaginal birth after cesarean (adjusted RR 0.71, 95% CI 0.60-0.85), but not among parous women without a previous cesarean (adjusted RR 1.16, 95% CI 1.00-1.34)., Interpretation: Episiotomy use has declined in Canada for all vaginal deliveries. The protective association between episiotomy and obstetric anal sphincter injury among women who gave birth by operative vaginal delivery (especially forceps) warrants reconsideration of clinical practice among nulliparous women and those attempting vaginal birth after cesarean., Competing Interests: Competing interests: None declared., (© 2019 Joule Inc. or its licensors.)
- Published
- 2019
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30. Surgical Innovation and the US Food and Drug Administration.
- Author
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Cundiff GW
- Subjects
- Humans, Medical Device Recalls legislation & jurisprudence, Pelvic Organ Prolapse surgery, Safety-Based Medical Device Withdrawals legislation & jurisprudence, United States, Surgical Mesh adverse effects, United States Food and Drug Administration
- Published
- 2019
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31. Morbidity and Mortality Associated With Forceps and Vacuum Delivery at Outlet, Low, and Midpelvic Station.
- Author
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Muraca GM, Sabr Y, Lisonkova S, Skoll A, Brant R, Cundiff GW, and Joseph KS
- Subjects
- Adult, Birth Injuries mortality, Female, Gestational Age, Humans, Labor Stage, Second, Obstetric Labor Complications mortality, Obstetrical Forceps, Pregnancy, Retrospective Studies, Vacuum Extraction, Obstetrical instrumentation, Young Adult, Birth Injuries epidemiology, Cesarean Section adverse effects, Dystocia surgery, Fetal Distress surgery, Obstetric Labor Complications epidemiology, Vacuum Extraction, Obstetrical adverse effects
- Abstract
Objective: This study sought to quantify perinatal and maternal morbidity and mortality associated with forceps and vacuum delivery compared with Caesarean delivery in the second stage of labour and to estimate whether these associations differed by pelvic station., Methods: The investigators conducted a population-based, retrospective cohort study of term singleton deliveries by operative delivery with prolonged second stage of labour in Canada (2003-2013) using national hospitalization data. The primary study outcomes were severe perinatal morbidity and mortality (i.e., seizures, assisted ventilation, severe birth trauma, and perinatal death) and severe maternal morbidity and mortality (i.e., severe postpartum hemorrhage, cardiac complication, and maternal death). Logistic regression was used to estimate adjusted odds ratios (aOR) and 95% confidence intervals (CI) after stratifying by indication (dystocia or fetal distress). The Breslow-Day chi-square test for heterogeneity in ORs was used to test effect modification by pelvic station (outlet, low, or midpelvic)., Results: There were 61 106 deliveries included in the study. Among women with dystocia, forceps and vacuum deliveries were associated with higher rates of perinatal morbidity and mortality compared with Caesarean delivery (forceps: aOR 1.56; 95% CI 1.13-2.17; vacuum: aOR 1.44; 95% CI 1.06-1.97). Vacuum delivery was associated with lower rates of maternal morbidity and mortality compared with Caesarean delivery (dystocia: aOR 0.64; 95% CI 0.51-0.81; fetal distress: aOR 0.43; 95% CI 0.32-0.57). Pelvic station did not significantly modify the associations between forceps or vacuum and perinatal or maternal morbidity and mortality., Conclusion: Forceps and vacuum delivery is associated with increased rates of severe perinatal morbidity and mortality compared with Caesarean delivery among women with dystocia, whereas vacuum delivery is associated with decreased rates of severe maternal morbidity and mortality., (Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2019
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32. Authors/ reply re: Perinatal and maternal morbidity and mortality among term singletons following mid cavity operative vaginal delivery versus caesarean delivery.
- Author
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Muraca GM, Skoll A, Lisonkova S, Sabr Y, Brant R, Cundiff GW, and Joseph KS
- Subjects
- Female, Humans, Pregnancy, Term Birth, Cesarean Section, Delivery, Obstetric
- Published
- 2018
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33. Foundation for an evidence-informed algorithm for treating pelvic floor mesh complications: a review.
- Author
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Cundiff GW, Quinlan DJ, van Rensburg JA, and Slack M
- Subjects
- Female, Humans, Pelvic Floor surgery, Algorithms, Decision Support Techniques, Pelvic Organ Prolapse surgery, Postoperative Complications surgery, Surgical Mesh adverse effects
- Abstract
To address evidence gaps on the management of complications related to mesh in pelvic floor surgery, we created an evidence-based algorithm that includes defining evidence gaps. We utilized the Delphi method within a panel of surgeons treating mesh complications to define a treatment strategy. The first round provided a list of clinically based postulates that informed a review expanding postulates to recommendations and included grading of the quality of evidence. A second round informed the final algorithm. While the quality of the available evidence is low, it provides a framework for planning diagnosis and management of mesh-related complications., Tweetable Abstract: Removal of mesh must balance resolution of complications with the risk of removal and recurrence of pelvic floor symptoms., (© 2018 Royal College of Obstetricians and Gynaecologists.)
- Published
- 2018
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34. Ecological association between operative vaginal delivery and obstetric and birth trauma.
- Author
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Muraca GM, Lisonkova S, Skoll A, Brant R, Cundiff GW, Sabr Y, and Joseph KS
- Subjects
- Adult, Canada epidemiology, Delivery, Obstetric statistics & numerical data, Episiotomy, Extraction, Obstetrical statistics & numerical data, Female, Health Care Surveys, Humans, Infant, Newborn, Lacerations, Pregnancy, Birth Injuries epidemiology, Cesarean Section statistics & numerical data, Delivery, Obstetric adverse effects, Extraction, Obstetrical adverse effects, Obstetric Labor Complications epidemiology, Perineum injuries
- Abstract
Background: Increased use of operative vaginal delivery (use of forceps, vacuum or other device) has been recommended to address high rates of cesarean delivery. We sought to determine the association between rates of operative vaginal delivery and obstetric trauma and severe birth trauma., Methods: We carried out an ecological analysis of term, singleton deliveries in 4 Canadian provinces (2004-2014) using data from the Canadian Institute for Health Information. The primary exposure was mode of delivery. The primary outcomes were obstetric trauma and severe birth trauma., Results: Data on 1 938 913 deliveries were analyzed. The rate of obstetric trauma was 7.2% in nulliparous women, and 2.2% and 2.7% among parous women without and with a previous cesarean delivery, respectively, and rates of severe birth trauma were 2.1, 1.7 and 0.7 per 1000, respectively. Each 1% absolute increase in rates of operative vaginal delivery was associated with a higher frequency of obstetric trauma among nulliparous women (adjusted rate ratio [ARR] 1.06, 95% confidence interval [CI] 1.05-1.06), parous women without a previous cesarean delivery (ARR 1.10, 95% CI 1.08-1.13) and parous women with a previous cesarean delivery (ARR 1.11, 95% CI 1.07-1.16). Operative vaginal delivery was associated with more frequent severe birth trauma, but only in nulliparous women (ARR 1.05, 95% CI 1.03-1.07). In nulliparous women, sequential vacuum and forceps instrumentation was associated with the largest increase in obstetric trauma (ARR 1.44, 95% CI 1.35-1.55) and birth trauma (ARR 1.53, 95% CI 1.03-2.27)., Interpretation: Increases in population rates of operative vaginal delivery are associated with higher population rates of obstetric trauma, and in nulliparous women with severe birth trauma., Competing Interests: Competing interests: None declared., (© 2018 Joule Inc. or its licensors.)
- Published
- 2018
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35. Authors' reply re: Perinatal and maternal morbidity and mortality among term singletons following midcavity operative vaginal delivery versus caesarean delivery.
- Author
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Muraca GM, Skoll A, Lisonkova S, Sabr Y, Brant R, Cundiff GW, and Joseph KS
- Subjects
- Female, Humans, Pregnancy, Term Birth, Cesarean Section, Delivery, Obstetric
- Published
- 2018
- Full Text
- View/download PDF
36. Perinatal and maternal morbidity and mortality among term singletons following midcavity operative vaginal delivery versus caesarean delivery.
- Author
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Muraca GM, Skoll A, Lisonkova S, Sabr Y, Brant R, Cundiff GW, and Joseph KS
- Subjects
- Adult, British Columbia epidemiology, Female, Humans, Infant, Newborn, Maternal Mortality, Obstetric Labor Complications mortality, Obstetrical Forceps adverse effects, Perinatal Mortality, Pregnancy, Retrospective Studies, Term Birth, Young Adult, Birth Injuries mortality, Cesarean Section adverse effects, Delivery, Obstetric adverse effects, Dystocia mortality, Fetal Distress mortality
- Abstract
Objective: To quantify severe perinatal and maternal morbidity/mortality associated with midcavity operative vaginal delivery compared with caesarean delivery., Design: Population-based, retrospective cohort study., Setting: British Columbia, Canada., Population: Term, singleton deliveries (2004-2014) by attempted midcavity operative vaginal delivery or caesarean delivery in the second stage of labour, stratified by indication for operative delivery (n = 10 901 deliveries; 5057 indicated for dystocia, 5844 for fetal distress)., Methods: Multinomial propensity scores and mulitvariable log-binomial regression models were used to estimate adjusted rate ratios (ARR) and 95% confidence intervals (95% CI)., Main Outcome Measures: Composite severe perinatal morbidity/mortality (e.g. convulsions, severe birth trauma and perinatal death) and severe maternal morbidity (e.g. severe postpartum haemorrhage, shock, sepsis and cardiac complications)., Results: Among deliveries with dystocia, attempted midcavity operative vaginal delivery was associated with higher rates of severe perinatal morbidity/mortality compared with caesarean delivery (forceps ARR 2.11, 95% CI 1.46-3.07; vacuum ARR 2.71, 95% CI 1.49-3.15; sequential ARR 4.68, 95% CI 3.33-6.58). Rates of severe maternal morbidity/mortality were also higher following midcavity operative vaginal delivery (forceps ARR 1.57, 95% CI 1.05-2.36; vacuum ARR 2.29, 95% CI 1.57-3.36). Among deliveries with fetal distress, there were significant increases in severe perinatal morbidity/mortality following attempted midcavity vacuum (ARR 1.28, 95% CI 1.04-1.61) and in severe maternal morbidity following attempted midcavity forceps delivery (ARR 2.34, 95% CI 1.54-3.56)., Conclusion: Attempted midcavity operative vaginal delivery is associated with higher rates of severe perinatal morbidity/mortality and severe maternal morbidity, though these effects differ by indication and instrument., Tweetable Abstract: Perinatal and maternal morbidity is increased following midcavity operative vaginal delivery., (© 2017 The Authors. BJOG An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd on behalf of Royal College of Obstetricians and Gynaecologists.)
- Published
- 2018
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37. Pregnancy-Associated Pelvic Floor Health Knowledge and Reduction of Symptoms: The PREPARED Randomized Controlled Trial.
- Author
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Hyakutake MT, Han V, Baerg L, Koenig NA, Cundiff GW, Lee T, and Geoffrion R
- Subjects
- Adult, Delivery, Obstetric statistics & numerical data, Female, Humans, Patient Satisfaction statistics & numerical data, Pregnancy, Quality of Life, Exercise, Health Knowledge, Attitudes, Practice, Patient Education as Topic methods, Pelvic Floor physiology, Prenatal Care methods
- Abstract
Objectives: Pregnancy and childbirth can lead to pelvic floor disorders, yet this topic is not routine in antenatal education. We aimed to determine the impact of a pregnancy workshop on women's postpartum pelvic floor health knowledge, performance of pelvic floor muscle exercises (PFME), symptoms, condition-specific quality of life, mode of delivery, and satisfaction., Methods: This was a RCT. Pregnant primiparous women in a tertiary care centre received a pelvic floor health workshop intervention versus routine prenatal care. Thirty-six participants/group were needed to detect a significant knowledge difference (power = 0.80, α = 0.05). Participants completed questionnaires at recruitment and six weeks postpartum. Main outcome measures were: difference between groups in knowledge scores; PFME-specific knowledge and practice; pelvic symptoms and condition-specific quality of life; and mode of and satisfaction with delivery., Results: Fifty women were recruited per group; 40 attended the workshop. Women were Caucasian (72%), college educated (96%), mean age 33.2. Mean demographics did not differ. Postpartum data were available for 37 women per group. The intervention group scored higher on a pelvic floor knowledge questionnaire (mean score 31.2/39 vs. 29.3/39, P = 0.02, 95% CI 0.3, 3.6). 58.3% of intervention participants reported daily performance of PFME compared with 22.9% of controls (P = 0.002) and rated higher confidence in correct performance (P = 0.004). The intervention group reported fewer bowel symptoms (P = 0.046). There were no differences in urinary or prolapse symptoms, mode of delivery, complications, or satisfaction., Conclusion: A pelvic floor health workshop improves postpartum knowledge, performance of PFME, and bowel-specific quality of life., (Copyright © 2018 Society of Obstetricians and Gynaecologists of Canada. Published by Elsevier Inc. All rights reserved.)
- Published
- 2018
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38. Response to "Data limitations may affect conclusions in study of vaginal delivery at midpelvic station".
- Author
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Muraca GM, Skoll A, Lisonkova S, Sabr Y, Brant R, Cundiff GW, and Joseph KS
- Subjects
- Female, Humans, Pregnancy, Delivery, Obstetric, Obstetrical Forceps
- Abstract
Competing Interests: Competing interests: None declared.
- Published
- 2017
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39. The authors reply to "The end of forceps deliveries?" and "Beware selection bias".
- Author
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Muraca GM, Lisonkova S, Joseph KS, Skoll A, Cundiff GW, Brant R, and Sabr Y
- Subjects
- Delivery, Obstetric, Extraction, Obstetrical, Female, Humans, Pregnancy, Obstetrical Forceps, Selection Bias
- Abstract
Competing Interests: Competing interests: None declared.
- Published
- 2017
- Full Text
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40. Mesh in POP surgery should be based on the risk of the procedure, not the risk of recurrence.
- Author
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Cundiff GW
- Subjects
- Female, Humans, Recurrence, Risk Assessment, Risk Factors, Pelvic Organ Prolapse surgery, Surgical Mesh adverse effects
- Abstract
The still unfolding story of mesh use in surgery for pelvic organ prolapse (POP) offers insights into the factors that influence how we interpret evidence in assessing new technology. Our adoption of mesh in prolapse surgery was influenced by a paradigm shift from treating to preventing recurrent prolapse. This shift is largely unsupported by data and fails to account for the added risk associated with mesh use. This commentary explores unconscious factors that influence our interpretation of innovation and proposes a new approach to evaluating new surgical technologies that balances benefit and risk. Counseling patients about treatments using the benefit-risk approach offers a more balanced perspective. Using a formal benefit-risk assessment in the scientific evaluation of treatments will also provide a more balanced approach that supports the scientific process and patients who undergo treatment.
- Published
- 2017
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41. Perinatal and maternal morbidity and mortality after attempted operative vaginal delivery at midpelvic station.
- Author
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Muraca GM, Sabr Y, Lisonkova S, Skoll A, Brant R, Cundiff GW, and Joseph KS
- Subjects
- Adult, Canada, Databases, Factual, Female, Humans, Infant, Newborn, Logistic Models, Maternal Mortality, Multivariate Analysis, Odds Ratio, Perinatal Mortality, Pregnancy, Young Adult, Birth Injuries epidemiology, Cesarean Section adverse effects, Dystocia epidemiology, Obstetric Labor Complications epidemiology, Obstetrical Forceps adverse effects, Postpartum Hemorrhage epidemiology
- Abstract
Background: Increased use of operative vaginal delivery (i.e., forceps or vacuum application), of which 20% occurs at midpelvic station, has been advocated to reduce the rate of cesarean delivery. We aimed to quantify severe perinatal and maternal morbidity and mortality associated with attempted midpelvic operative vaginal delivery., Methods: We studied all term singleton deliveries in Canada between 2003 and 2013, by attempted midpelvic operative vaginal or cesarean delivery with labour (with and without prolonged second stage). The primary outcomes were composite severe perinatal morbidity and mortality (e.g., convulsions, assisted ventilation, severe birth trauma and perinatal death), and composite severe maternal morbidity and mortality (e.g., severe postpartum hemorrhage, shock, sepsis, cardiac complications, acute renal failure and death)., Results: The study population included 187 234 deliveries. Among women with dystocia and prolonged second stage of labour, midpelvic operative vaginal delivery was associated with higher rates of severe perinatal morbidity and mortality compared with cesarean delivery (forceps, adjusted odds ratio [AOR] 1.81, 95% confidence interval [CI] 1.24 to 2.64; vacuum, AOR 1.81, 95% CI 1.17 to 2.80; sequential instruments, AOR 3.19, 95% CI 1.73 to 5.88), especially with higher rates of severe birth trauma. Rates of severe maternal morbidity and mortality were not significantly different after operative vaginal delivery, although rates of obstetric trauma were higher (forceps, AOR 4.51, 95% CI 4.04 to 5.02; vacuum, AOR 2.70, 95% CI 2.35 to 3.09; sequential instruments, AOR 4.24, 95% CI 3.46 to 5.19). Among women with fetal distress, similar associations were seen for severe birth trauma and obstetric trauma, although vacuum was associated with lower rates of severe maternal morbidity and mortality (AOR 0.52, 95% CI 0.33 to 0.80). Associations tended to be stronger among women without a prolonged second stage., Interpretation: Midpelvic operative vaginal delivery is associated with higher rates of severe birth trauma and obstetric trauma, whereas overall rates of severe perinatal and maternal morbidity and mortality vary by indication and operative instrument., Competing Interests: Competing interests: None declared., (© 2017 Canadian Medical Association or its licensors.)
- Published
- 2017
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42. Observational Study of Neonatal Safety for Outpatient Labour Induction Priming with Dinoprostone Vaginal Insert.
- Author
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Cundiff GW, Simpson ML, Koenig N, and Lee T
- Subjects
- Administration, Intravaginal, Adult, Apgar Score, Cohort Studies, Delivery, Obstetric methods, Female, Fetal Membranes, Premature Rupture, Gestational Age, Humans, Outpatients, Pregnancy, Pregnancy, Prolonged, Retrospective Studies, Ambulatory Care, Dinoprostone administration & dosage, Dinoprostone adverse effects, Labor, Induced methods, Oxytocics, Pregnancy Outcome
- Abstract
Objectives: To evaluate the safety of outpatient induction with dinoprostone insert in low-risk labour inductions for premature rupture of membranes or postdates gestation., Methods: This retrospective cohort study compared outpatient labour induction priming with inpatient induction in terms of neonatal safety, mode of delivery, and obstetrical parameters. The sample included all inductions for premature rupture of membranes or postdate gestation. The analysis used logistic regression. The statistical power of the sample was 80% to detect a difference of 5.6% for the composite neonatal safety outcome (5-minute Apgar score <7 and NICU admission for >12 hours or transfer to a level III nursery)., Results: Compared with the inpatient cohort (n = 568), the outpatient cohort (n = 611) included more postdate gestations (93% vs. 67%) with less cervical dilatation (0.5 cm vs. 1.0 cm) and larger infants (3705 g vs. 3551 g). There were no differences in measures of neonatal safety or mode of delivery. The outpatient cohort required more dinoprostone inserts (1.59 vs. 1.23) and were less likely to deliver within 24 hours (OR 0.24, 95% CI 0.17 to 0.34) but were also less likely to deliver by CS (OR 0.71, 95% CI 0.54 to 0.95), after adjusting for obstetrical parameters., Conclusion: An outpatient model of labour induction using dinoprostone inserts is feasible and safe., (Copyright © 2017 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.)
- Published
- 2017
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43. Is Pelvic Floor Dysfunction an Independent Threat to Sexual Function? A Cross-Sectional Study in Women With Pelvic Floor Dysfunction.
- Author
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Li-Yun-Fong RJ, Larouche M, Hyakutake M, Koenig N, Lovatt C, Geoffrion R, Brotto LA, Lee T, and Cundiff GW
- Subjects
- Adult, Aged, Comorbidity, Cross-Sectional Studies, Female, Humans, Middle Aged, Pelvic Floor Disorders physiopathology, Prevalence, Retrospective Studies, Surveys and Questionnaires, Urinary Bladder, Overactive epidemiology, Women's Health, Pelvic Floor physiopathology, Pelvic Floor Disorders epidemiology, Sexual Dysfunction, Physiological epidemiology, Urinary Incontinence epidemiology
- Abstract
Introduction: Prior studies have reported an association of sexual dysfunction with pelvic floor dysfunction (PFD), but without defining causation., Aim: To investigate predictors of sexual function in women with PFD, including pelvic organ prolapse, stress urinary incontinence, overactive bladder, obstructed defecation, and fecal incontinence., Methods: This retrospective cross-sectional study included 755 women (mean age = 56 years, 68% postmenopausal) referred for PFD (2008-2013). Subjects underwent standardized history and examination, including demographics and assessment of pelvic floor function and sexual function using validated quality-of-life instruments. The physical examination included body mass index, Pelvic Organ Prolapse Quantification measurements, and pelvic muscle strength (Oxford scale). Proportional odds regression analysis tested patient characteristics, PFD, and other determinants of sexual dysfunction as predictors of sexual function., Main Outcome Measures: The Pelvic Floor Distress Inventory (PFDI-20) and Pelvic Floor Impact Questionnaire (PFIQ-7) to assess PFD and the Short Personal Experiences Questionnaire to assess sexual function., Results: The prevalence of PFD included pelvic organ prolapse (72%), stress urinary incontinence (66%), overactive bladder (78%), fecal incontinence (41%), and obstructed defecation (70%). Most subjects (74%) had a sexual partner and most (56%) reported recent sexual intercourse. Participants reported a low level of sexual desire and sexual enjoyment and moderate levels of sexual arousal and orgasm. When stratified by sexual enjoyment, 46% enjoyed sex and this group had lower PFDI and PFIQ scores, reflecting less quality-of-life burden. Pelvic organ prolapse, obstructed defecation, and fecal incontinence were associated with not enjoying sex. However, when adjusted for other determinants of sexual dysfunction (eg, aging, dyspareunia, atrophy, and partner issues), these associations disappeared., Conclusion: Women with PFD also have a large burden of sexual dysfunction, although this appears to be mediated by factors not unique to PFD., (Copyright © 2016 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.)
- Published
- 2017
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44. Vaginal and laparoscopic mesh hysteropexy for uterovaginal prolapse: a parallel cohort study.
- Author
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Gutman RE, Rardin CR, Sokol ER, Matthews C, Park AJ, Iglesia CB, Geoffrion R, Sokol AI, Karram M, Cundiff GW, Blomquist JL, and Barber MD
- Subjects
- Aged, Aged, 80 and over, Cohort Studies, Female, Humans, Middle Aged, Prospective Studies, Sacrum, Vagina, Gynecologic Surgical Procedures methods, Laparoscopy methods, Postoperative Complications epidemiology, Surgical Mesh, Uterine Prolapse surgery
- Abstract
Background: There is growing interest in uterine conservation at the time of surgery for uterovaginal prolapse, but limited data compare different types of hysteropexy., Objective: We sought to compare 1-year efficacy and safety of laparoscopic sacral hysteropexy and vaginal mesh hysteropexy., Study Design: This multicenter, prospective parallel cohort study compared laparoscopic sacral hysteropexy to vaginal mesh hysteropexy at 8 institutions. We included women ages 35-80 years who desired uterine conservation, were done with childbearing, and were undergoing 1 of the above procedures for stage 2-4 symptomatic anterior/apical uterovaginal prolapse (anterior descent at or beyond the hymen [Aa or Ba ≥ 0] and apical descent at or below the midvagina [C ≥ -TVL/2]). We excluded women with cervical elongation, prior mesh prolapse repair, cervical dysplasia, chronic pelvic pain, uterine abnormalities, and abnormal bleeding. Cure was defined as no prolapse beyond the hymen and cervix above midvagina (anatomic), no vaginal bulge sensation (symptomatic), and no reoperations. Pelvic Organ Prolapse Quantification examination and validated questionnaires were collected at baseline and 12 months including the Pelvic Floor Distress Inventory Short Form, Female Sexual Function Index, and Patient Global Impression of Improvement. In all, 72 subjects/group were required to detect 94% vs 75% cure (80% power, 15% dropout). Intention-to-treat analysis was used with logistic regression adjusting for baseline differences., Results: We performed 74 laparoscopic sacral hysteropexy and 76 vaginal mesh hysteropexy procedures from July 2011 through May 2014. Laparoscopic patients were younger (P < .001), had lower parity (P = .006), were more likely premenopausal (P = .008), and had more severe prolapse (P = .02). Laparoscopic procedure (174 vs 64 minutes, P < .0001) and total operating time (239 vs 112 minutes, P < .0001) were longer. There were no differences in blood loss, complications, and hospital stay. One-year outcomes for the available 83% laparoscopic and 80% vaginal hysteropexy patients revealed no differences in anatomic (77% vs 80%; adjusted odds ratio, 0.48; P = .20), symptomatic (90% vs 95%; adjusted odds ratio, 0.40; P = .22), or composite (72% vs 74%; adjusted odds ratio, 0.58; P = .27) cure. Mesh exposures occurred in 2.7% laparoscopic vs 6.6% vaginal hysteropexy (P = .44). A total of 95% of each group were very much better or much better. Pelvic floor symptom and sexual function scores improved for both groups with no difference between groups., Conclusion: Laparoscopic sacral hysteropexy and vaginal mesh hysteropexy had similar 1-year cure rates and high satisfaction., (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Published
- 2017
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45. Balancing the Needs of Patients and Learners in Surgery.
- Author
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Cundiff GW and Geoffrion R
- Subjects
- Humans, Patient Safety, Students, Medical, Surgeons, Surgical Procedures, Operative education, Surgical Procedures, Operative standards
- Abstract
In this commentary, we explore the need for academic physicians to balance the needs of their patients and of learners during surgery. We approach this discussion from the perspective of the duty of care to the patient and reflect on methods to respect this duty of care but still maximize the educational experience of the learner without jeopardizing the patient's health. We also identify pedagogical methods to facilitate this balance, both in routine situations and during unforeseen events., (Copyright © 2016 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.)
- Published
- 2016
- Full Text
- View/download PDF
46. An Assessment of the Continuing Surgical Education Program, a Surgical Preceptor Program for Faculty Members.
- Author
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Cundiff GW and Geoffrion R
- Subjects
- British Columbia, Female, Humans, Hysterectomy, Vaginal, Retrospective Studies, Education, Medical, Continuing statistics & numerical data, Hysterectomy education, Hysterectomy statistics & numerical data, Laparoscopy education, Laparoscopy statistics & numerical data
- Abstract
Objective: The Continuing Surgical Education Preceptor program (CSEP) was designed to meet population needs by facilitating development of new skills by practising surgeons. Elements include entry criteria, dedicated OR time, assigned preceptors, structured assessment of competence, a mechanism for credentialing, and a reimbursement model. This study analyzed the effectiveness of the CSEP in increasing the number of clinician educators performing laparoscopic hysterectomy (LH) without compromising rates of vaginal hysterectomy (VH) and in enhancing residents' training in performing minimally invasive hysterectomy (MIH; either LH or VH)., Methods: We performed a retrospective descriptive study to longitudinally analyze the numbers and proportions of different surgical approaches to hysterectomy at two hospital sites over five years. The CSEP was implemented differently at the two sites. Success of the program was indicated by a surgeon performing 50% or more of hysterectomies as MIH. To assess the impact on resident education, we longitudinally analyzed the number of hysterectomy teaching cases performed as MIH., Results: The proportion of surgeons performing 50% of hysterectomies as MIH steadily increased in the first five years after implementation of the CSEP. At one hospital, the proportion increased from 13% to 56%, due to an increase in LH cases with no change in VH cases. The proportion of resident LH teaching cases increased from 0% to 26%, with a similar rise in the proportion of MIH cases, although it did not quite reach the target proportion of 50% or more. Contrasting the experience of the CSEP between two hospitals revealed that having OR time dedicated to MIH cases provided significantly better results., Conclusions: The CSEP is an effective and sustainable model of lifelong learning applied to teaching practising surgeons new surgical skills., (Copyright © 2016 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.)
- Published
- 2016
- Full Text
- View/download PDF
47. It is a Bigger Question Than What to Do With the Uterus.
- Author
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Cundiff GW
- Subjects
- Age Factors, Female, Humans, Postoperative Complications etiology, Postoperative Complications surgery, Risk, Secondary Prevention, Gynecologic Surgical Procedures adverse effects, Organ Sparing Treatments psychology, Pelvic Organ Prolapse surgery, Surgical Mesh adverse effects
- Published
- 2016
- Full Text
- View/download PDF
48. Pelvic Floor Health Education: Can a Workshop Enhance Patient Counseling During Pregnancy?
- Author
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Hyakutake MT, Han V, Cundiff GW, Baerg L, Koenig NA, Lee T, and Geoffrion R
- Subjects
- Adult, Delivery, Obstetric adverse effects, Female, Health Knowledge, Attitudes, Practice, Humans, Pregnancy, Prospective Studies, Surveys and Questionnaires, Directive Counseling methods, Health Education, Pelvic Floor injuries, Pelvic Floor Disorders etiology, Prenatal Care methods
- Abstract
Objectives: Pelvic floor disorders commonly affect women's quality of life. Their etiology is multifactorial, yet pregnancy and vaginal delivery (VD) are major inciting risk factors. Our objectives were to assess pelvic floor health information given by maternity providers to their pregnant patients, to create a pelvic floor health information workshop, and to determine its impact on women's preferences for mode of delivery., Methods: This descriptive study recruited primiparous women with a singleton gestation at St Paul's Hospital in Vancouver, Canada. Participants received a 2-hour workshop describing pelvic floor disorders and pregnancy, modes of delivery, as well as strategies for maintaining pelvic floor health and preventing disease. Women completed questionnaires assessing baseline knowledge and level of comfort with different modes of delivery before and after the workshop., Results: Forty participants completed the workshop. Seventy percent had an obstetrician, 20% had a midwife, and 10% had a family physician. Five percent of the participants reported receiving information regarding pelvic organ prolapse as well as urinary and fecal incontinence. The workshop did not influence women's preferred mode of delivery, including VD (P = 1.00), forceps-assisted VD (P = 0.48), vacuum-assisted VD (P = 0.68), postlabor cesarean delivery (P = 0.32), and elective cesarean delivery (P = 0.86)., Conclusions: Current antenatal care is lacking in the area of pelvic floor health education. Patient counseling can be enhanced via a standard workshop. Concerns about negatively influencing women's preferences for mode of delivery are unwarranted, as the pelvic floor health workshop, given during pregnancy, did not significantly change participants' preferences.
- Published
- 2016
- Full Text
- View/download PDF
49. At last, a standardized laparoscopy curriculum for gynecology residents.
- Author
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Cundiff GW
- Subjects
- Clinical Competence, Humans, Internship and Residency, Laparoscopy education, Obstetrics education, Curriculum, Gynecology education
- Published
- 2016
- Full Text
- View/download PDF
50. Temporal trends in obstetric trauma and inpatient surgery for pelvic organ prolapse: an age-period-cohort analysis.
- Author
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Lisonkova S, Lavery JA, Ananth CV, Chen I, Muraca G, Cundiff GW, and Joseph KS
- Subjects
- Adolescent, Adult, Cohort Studies, Female, Humans, Pregnancy, Retrospective Studies, Risk Factors, Young Adult, Cesarean Section adverse effects, Delivery, Obstetric adverse effects, Pelvic Organ Prolapse etiology, Pregnancy Complications etiology
- Abstract
Background: The rates of cesarean delivery have increased over time in industrialized countries, while the rates of instrumental vaginal delivery have declined. Instrumental vaginal delivery and obstetric trauma are risk factors for pelvic floor disorders., Objective: We carried out a population-based study to quantify the association between temporal changes in obstetric trauma during childbirth and temporal changes in surgery for pelvic organ prolapse., Study Design: We designed a retrospective analysis to examine age-specific trends in vaginal and cesarean delivery, obstetric trauma, and surgery for pelvic organ prolapse among all women (pregnant and nonpregnant) in Washington State, from 1987 through 2009. Cases of obstetric trauma (including severe perineal tears and high vaginal lacerations) and inpatient surgery for pelvic organ prolapse were identified among all hospitalizations. Temporal trends and age-period-cohort regression analyses were used to quantify the time period, age, and birth cohort effects among women born from 1920 through 1980., Results: From 1987 through 2009, cesarean delivery rates among women aged 15-44 years increased from 12.7-18.1 per 1000 women, vaginal delivery rates remained stable, and instrumental vaginal delivery rates declined from 6.3-3.9 per 1000 women. Obstetric trauma decreased from 6.7 in 1987 to 2.5 per 1000 women aged 15-44 years in 2009. Surgery for pelvic organ prolapse decreased from 2.1 in 1987 to 1.4 per 1000 women aged 20-84 years in 2009. Obstetric trauma rates in 1987 through 1999 among women 15-44 years old were strongly correlated with the rates of surgery for pelvic organ prolapse among women 25-54 years of age 10 years later in 1997 through 2009 (correlation coefficient 0.87, P < .001). Similarly, rates of midpelvic forceps delivery in 1987 through 1999 were correlated with the rates of surgery for pelvic organ prolapse 10 years later (correlation coefficient 0.72, P < .01). Regression analyses showed a strong effect of age on surgery for prolapse, temporal decline in surgery, and an effect of birth cohort, as younger cohorts (women born in ≥1965 vs 1940) had lower rates of surgery for pelvic organ prolapse., Conclusion: Temporal decline in instrumental vaginal delivery and obstetric trauma may have contributed to the reduction in surgery for pelvic organ prolapse., (Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2016
- Full Text
- View/download PDF
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