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5. An efficient synthesis of 5-aryl-4,5-dihydro-3-(5-methyl-1- p-tolyl-1 H-1,2,3-triazol-4-yl)-1-(4-phenylthiazol-2-yl)pyrazoles.

Author

Dong, Wang-Jun, Cui, Fu-Hong, Gao, Zhong-Lian, Li, Rong-Shan, Shen, Guo-Liang, and Dong, Heng-Shan

Subjects
*PYRAZOLES, *HETEROCYCLIC chemistry, *ANTIBACTERIAL agents, *ANTIFUNGAL agents, *HYPOGLYCEMIC agents, *ANTI-inflammatory agents, *MONOAMINE oxidase inhibitors
Abstract

Some new target products 5-aryl-4,5-dihydro-3-(5-methyl-1- p-tolyl-1 H-1,2,3-triazol-4-yl)-1-(4-phenylthiazol-2-yl)pyrazoles 5a-j have been synthesized by reaction of 2-bromo-1-phenylethanone and compounds 4a-j which were prepared from the combination of thiosemicarbazide and ( E)-3-aryl-1-(5-methyl-1- p-tolyl-1 H-1,2,3-triazol-4-yl)-prop-2-en-1-ones 3a-j. All the structures were established by MS, IR, CHN, and 1H NMR spectra data. Synthesis of structure diversity is applied. J. Heterocyclic Chem., (2011). [ABSTRACT FROM AUTHOR]

Published
2011
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