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2. Long-term Outcomes with Spinal versus General Anesthesia for Hip Fracture Surgery: A Randomized Trial

Author

Vail, Emily A., Feng, Rui, Sieber, Frederick, Carson, Jeffrey L., Ellenberg, Susan S., Magaziner, Jay, Dillane, Derek, Marcantonio, Edward R., Sessler, Daniel I., Ayad, Sabry, Stone, Trevor, Papp, Steven, Donegan, Derek, Mehta, Samir, Schwenk, Eric S., Marshall, Mitchell, Jaffe, J. Douglas, Luke, Charles, Sharma, Balram, Azim, Syed, Hymes, Robert, Chin, Ki-Jinn, Sheppard, Richard, Perlman, Barry, Sappenfield, Joshua, Hauck, Ellen, Tierney, Ann, Horan, Annamarie D., Neuman, Mark D., Looke, Thomas, Bent, Sandra, Franco-Mora, Ariana, Hedrick, Pamela, Newbern, Matthew, Tadros, Rafik, Pealer, Karen, Vlassakov, Kamen, Buckley, Carolyn, Gavin, Lauren, Gorbatov, Svetlana, Gosnell, James, Steen, Talora, Vafai, Avery, Zeballos, Jose, Hruslinski, Jennifer, Cardenas, Louis, Berry, Ashley, Getchell, John, Quercetti, Nicholas, Hassan, Manal, Bajracharya, Gauasan, Billow, Damien, Bloomfield, Michael, Cuko, Evis, Elyaderani, Mehrun K., Hampton, Robert, Honar, Hooman, Khoshknabi, Dilara, Kim, Daniel, Krahe, David, Lew, Michael M., Maheshwer, Conjeevram B., Niazi, Azfar, Saha, Partha, Salih, Ahmed, de Swart, Robert J., Volio, Andrew, Bolkus, Kelly, DeAngelis, Matthew, Dodson, Gregory, Gerritsen, Jeffrey, McEniry, Brian, Mitrev, Ludmil, Kwofie, M. Kwesi, Belliveau, Anne, Bonazza, Flynn, Lloyd, Vera, Panek, Izabela, Dabiri, Jared, Chavez, Chris, Craig, Jason, Davidson, Todd, Dietrichs, Chad, Fleetwood, Cheryl, Foley, Mike, Getto, Chris, Hailes, Susie, Hermes, Sarah, Hooper, Andy, Koener, Greg, Kohls, Kate, Law, Leslie, Lipp, Adam, Losey, Allison, Nelson, William, Nieto, Mario, Rogers, Pam, Rutman, Steve, Scales, Garrett, Sebastian, Barbara, Stanciu, Tom, Lobel, Gregg, Giampiccolo, Michelle, Herman, Dara, Kaufman, Margit, Murphy, Bryan, Pau, Clara, Puzio, Thomas, Veselsky, Marlene, Apostle, Kelly, Boyer, Dory, Chen Fan, Brenda, Lee, Susan, Lemke, Mike, Merchant, Richard, Moola, Farhad, Payne, Kyrsten, Perey, Bertrand, Viskontas, Darius, Poler, Mark, D’Antonio, Patricia, O’Neill, Greg, Abdullah, Amer, Fish-Fuhrmann, Jamie, Giska, Mark, Fidkowski, Christina, Guthrie, Stuart Trent, Hakeos, William, Hayes, Lillian, Hoegler, Joseph, Nowak, Katherine, Beck, Jeffery, Cuff, Jaslynn, Gaski, Greg, Haaser, Sharon, Holzman, Michael, Malekzadeh, A. Stephen, Ramsey, Lolita, Schulman, Jeff, Schwartzbach, Cary, Azefor, Tangwan, Davani, Arman, Jaberi, Mahmood, Masear, Courtney, Haider, Syed Basit, Chungu, Carolyn, Ebrahimi, Ali, Fikry, Karim, Marcantonio, Andrew, Shelvan, Anitha, Sanders, David, Clarke, Collin, Lawendy, Abdel, Schwartz, Gary, Garg, Mohit, Kim, Joseph, Caruci, Juan, Commeh, Ekow, Cuevas, Randy, Cuff, Germaine, Franco, Lola, Furgiuele, David, Giuca, Matthew, Allman, Melissa, Barzideh, Omid, Cossaro, James, D’Arduini, Armando, Farhi, Anita, Gould, Jason, Kafel, John, Patel, Anuj, Peller, Abraham, Reshef, Hadas, Safur, Mohammed, Toscano, Fiore, Tedore, Tiffany, Akerman, Michael, Brumberger, Eric, Clark, Sunday, Friedlander, Rachel, Jegarl, Anita, Lane, Joseph, Lyden, John P., Mehta, Nili, Murrell, Matthew T., Painter, Nathan, Ricci, William, Sbrollini, Kaitlyn, Sharma, Rahul, Steel, Peter A.D., Steinkamp, Michele, Weinberg, Roniel, Stephenson Wellman, David, Nader, Antoun, Fitzgerald, Paul, Ritz, Michaela, Bryson, Greg, Craig, Alexandra, Farhat, Cassandra, Gammon, Braden, Gofton, Wade, Harris, Nicole, Lalonde, Karl, Liew, Allan, Meulenkamp, Bradley, Sonnenburg, Kendra, Wai, Eugene, Wilkin, Geoffrey, Troxell, Karen, Alderfer, Mary Ellen, Brannen, Jason, Cupitt, Christopher, Gerhart, Stacy, McLin, Renee, Sheidy, Julie, Yurick, Katherine, Chen, Fei, Dragert, Karen, Kiss, Geza, Malveaux, Halina, McCloskey, Deborah, Mellender, Scott, Mungekar, Sagar S., Noveck, Helaine, Sagebien, Carlos, Biby, Luat, McKelvy, Gail, Richards, Anna, Abola, Ramon, Ayala, Brittney, Halper, Darcy, Mavarez, Ana, Rizwan, Sabeen, Choi, Stephen, Awad, Imad, Flynn, Brendan, Henry, Patrick, Jenkinson, Richard, Kaustov, Lilia, Lappin, Elizabeth, McHardy, Paul, Singh, Amara, Donnelly, Joanne, Gonzalez, Meera, Haydel, Christopher, Livelsberger, Jon, Pazionis, Theresa, Slattery, Bridget, Vazquez-Trejo, Maritza, Baratta, Jaime, Cirullo, Michael, Deiling, Brittany, Deschamps, Laura, Glick, Michael, Katz, Daniel, Krieg, James, Lessin, Jennifer, Mojica, Jeffrey, Torjman, Marc, Jin, Rongyu, Salpeter, Mary Jane, Powell, Mark, Simmons, Jeffrey, Lawson, Prentiss, Kukreja, Promil, Graves, Shanna, Sturdivant, Adam, Bryant, Ayesha, Crump, Sandra Joyce, Verrier, Michelle, Green, James, Menon, Matthew, Applegate, Richard, Arias, Ana, Pineiro, Natasha, Uppington, Jeffrey, Wolinsky, Phillip, Gunnett, Amy, Hagen, Jennifer, Harris, Sara, Hollen, Kevin, Holloway, Brian, Horodyski, Mary Beth, Pogue, Trevor, Ramani, Ramachandran, Smith, Cameron, Woods, Anna, Warrick, Matthew, Flynn, Kelly, Mongan, Paul, Ranganath, Yatish, Fernholz, Sean, Ingersoll-Weng, Esperanza, Marian, Anil, Seering, Melinda, Sibenaller, Zita, Stout, Lori, Wagner, Allison, Walter, Alicia, Wong, Cynthia, Orwig, Denise, Goud, Maithri, Helker, Chris, Mezenghie, Lydia, Montgomery, Brittany, Preston, Peter, Schwartz, J. Sanford, Weber, Ramona, Fleisher, Lee A., Mehta, Samir, Stephens-Shields, Alisa J., Dinh, Cassandra, Schwartz, Aron, Chelly, Jacques E., Goel, Shiv, Goncz, Wende, Kawabe, Touichi, Khetarpal, Sharad, Monroe, Amy, Shick, Vladislav, Breidenstein, Max, Dominick, Timothy, Friend, Alexander, Mathews, Donald, Lennertz, Richard, Sanders, Robert, Akere, Helen, Balweg, Tyler, Bo, Amber, Doro, Christopher, Goodspeed, David, Lang, Gerald, Parker, Maggie, Rettammel, Amy, Roth, Mary, White, Marissa, Whiting, Paul, Allen, Brian F.S., Baker, Tracie, Craven, Debra, McEvoy, Matt, Turnbo, Teresa, Kates, Stephen, Morgan, Melanie, Willoughby, Teresa, Weigel, Wade, Auyong, David, Fox, Ellie, Welsh, Tina, Cusson, Bruce, Dobson, Sean, Edwards, Christopher, Harris, Lynette, Henshaw, Daryl, Johnson, Kathleen, McKinney, Glen, Miller, Scott, Reynolds, Jon, Segal, B. Scott, Turner, Jimmy, VanEenenaam, David, Weller, Robert, Lei, Jineli, Treggiari, Miriam, Akhtar, Shamsuddin, Blessing, Marcelle, Johnson, Chanel, Kampp, Michael, Kunze, Kimberly, OʼConnor, Mary, Gaskins, Lakisha J., Looke, Thomas, Tadros, Rafik, Vlassakov, Kamen, Cardenas, Louis, Hassan, Manal, Bolkus, Kelly, Mitrev, Ludmil, Kwofie, M. Kwesi, Dabiri, Jared, Lobel, Gregg, Poler, Mark, Giska, Mark, Sanders, David, Schwartz, Gary, Giuca, Matthew, Tedore, Tiffany, Nader, Antoun, Papp, Stephen, Bryson, Greg, Troxell, Karen, Kiss, Geza, Choi, Stephen, Powell, Mark, Applegate, Richard, Warrick, Matthew, Ranganath, Yatish, Elkassabany, Nabil, Chelly, Jacques E., Hoeft, Mark A., Lennertz, Richard, Sanders, Robert, Allen, Brian F.S., Kates, Stephen, Weigel, Wade, Li, Jinlei, Wijeysundera, Duminda N., Kheterpal, Sachin, Moore, Reneé H., Smith, Alexander K., Tosi, Laura L., Elkassabany, Nabil, Looke, Thomas, Menio, Diane, Mehta, Samir, Fleisher, Lee, Menio, Diane, Hruslinski, Jennifer, Ramsey, Lolita, Gaskins, Lakisha J., Langlois, Christine, Gaskins, Lakisha J., Mezenghie, Lydia, Montgomery, Brittany, Oduwole, Samuel, and Rose, Thomas

Published
2024
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7. Engaging patients as partners in a multicentre trial of spinal versus general anaesthesia for older adults

Author

Looke, Thomas, Bent, Sandra, Franco-Mora, Ariana, Hedrick, Pamela, Newbern, Matthew, Tadros, Rafik, Pealer, Karen, Marcantonio, Edward, Vlassakov, Kamen, Buckley, Carolyn, Gorbatov, Svetlana, Gosnell, James, Steen, Talora, Vafai, Avery, Zeballos, Jose, Cardenas, Louis, Berry, Ashley, Getchell, John, Quercetti, Nicholas, Sessler, Daniel I., Ayad, Sabry, Hassan, Manal, Ali, Assad, Bajracharya, Gauasan, Billow, Damien, Bloomfield, Michael, Elliott, Kavita, Hampton, Robert, He, Linda, Honar, Hooman, Khoshknabi, Dilara, Kim, Daniel, Minko, Paul, Morris, Adam, Niazi, Azfar, Nutcharoen, Tara, Roberts, Jeffrey, Saha, Partha, Salih, Ahmed, Skolaris, Alexis, Stang, Taylor, Strimbu, Victor, Templeton, Jesse, Volio, Andrew, Wang, Jiayi, Bolkus, Kelly, DeAngelis, Matthew, Dodson, Gregory, Gerritsen, Jeffrey, McEniry, Brian, Mitrev, Ludmil, Kwofie, Kwesi, Bonazza, Flynn, Lloyd, Vera, Panek, Izabela, Dabiri, Jared, Chavez, Chris, Craig, Jason, Davidson, Todd, Dietrichs, Chad, Fleetwood, Cheryl, Foley, Mike, Getto, Chris, Hailes, Susie, Hermes, Sarah, Hooper, Andy, Koener, Greg, Kohls, Kate, Law, Leslie, Lipp, Adam, Losey, Allison, Nelson, William, Nieto, Mario, Rogers, Pam, Rutman, Steve, Scales, Garrett, Sebastian, Barbara, Stanciu, Tom, Lobel, Gregg, Giampiccolo, Michelle, Herman, Dara, Kaufman, Margit, Murphy, Bryan, Pau, Clara, Puzio, Thomas, Veselsky, Marlene, Stone, Trevor, Apostle, Kelly, Boyer, Dory, Fan, Brenda Chen, Lee, Susan, Lemke, Mike, Merchant, Richard, Moola, Farhad, Payne, Kyrsten, Perey, Bertrand, Viskontas, Darius, Poler, Mark, D'Antonio, Patricia, Sheppard, Richard, Abdullah, Amer, Fish-Fuhrmann, Jamie, Giska, Mark, Fidkowski, Christina, Guthrie, Trent, Hakeos, William, Hayes, Lillian, Hoegler, Joseph, Nowak, Katherine, Hymes, Robert, Beck, Jeffery, Cuff, Jaslynn, Gaski, Greg, Haaser, Sharon, Holzman, Michael, Malekzadeh, A. Stephen, Ramsey, Lolita, Schulman, Jeff, Schwartzbach, Cary, Sieber, Frederick, Azefor, Tangwan, Brown, Charles, Davani, Arman, Jaberi, Mahmood, Masear, Courtney, Sharma, Balram, Haider, Syed Basit, Chungu, Carolyn, Ebrahimi, Ali, Fikry, Karim, Gannon, Kerri, Marcantonio, Andrew, Pace, Meredith, Sanders, David, Clarke, Collin, Lawendy, Abdel, Schwartz, Gary, Garg, Mohit, Kim, Joseph, Marshall, Mitchell, Caurci, Juan, Commeh, Ekow, Cuevas, Randy, Cuff, Germaine, Franco, Lola, Furguiele, David, Giuca, Matthew, Allman, Melissa, Barzideh, Omid, Cossaro, James, D'Arduini, Armando, Farhi, Anita, Gould, Jason, Kafel, John, Patel, Anuj, Peller, Abraham, Reshef, Hadas, Safur, Mohammed, Toscano, Fiore, Tedore, Tiffany, Akerman, Michael, Brumberger, Eric, Clark, Sunday, Friedlander, Rachel, Jegarl, Anita, Lane, Joseph, Lyden, John P., Mehta, Nili, Murrell, Matthew T., Painter, Nathan, Ricci, William, Sbrollini, Kaitlyn, Sharma, Rahul, Steel, Peter A.D., Steinkamp, Michele, Weinberg, Roniel, Wellman, David Stephenson, Nader, Antoun, Fitzgerald, Paul, Ritz, Michaela, Papp, Steven, Bryson, Greg, Craig, Alexandra, Farhat, Cassandra, Gammon, Braden, Gofton, Wade, Harris, Nicole, Lalonde, Karl, Liew, Allan, Meulenkamp, Bradley, Sonnenburg, Kendra, Wai, Eugene, Wilkin, Geoffrey, Donegan, Derek, Dinh, Cassandra, Elkassabany, Nabil, Horan, Annamarie, Mehta, Samir, Troxell, Karen, Alderfer, Mary Ellen, Brannen, Jason, Cupitt, Christopher, Gerhart, Stacy, McLin, Renee, Sheidy, Julie, Yurick, Katherine, Carson, Jeffrey, Chen, Fei, Dragert, Karen, Kiss, Geza, Malveaux, Halina, McCloskey, Deborah, Mellender, Scott, Mungekar, Sagar S., Noveck, Helaine, Sagebien, Carlos, Perlman, Barry, Biby, Luat, McKelvy, Gail, Richards, Anna, Azim, Syed, Abola, Ramon, Ayala, Brittney, Halper, Darcy, Mavarez, Ana, Choi, Stephen, Awad, Imad, Flynn, Brendan, Henry, Patrick, Jenkinson, Richard, Kaustov, Lilia, Lappin, Elizabeth, McHardy, Paul, Singh, Amara, Hauck, Ellen, Donnelly, Joanne, Gonzalez, Meera, Haydel, Christopher, Livelsberger, Jon, Pazionis, Theresa, Slattery, Bridget, Vazquez-Trejo, Maritza, Schwenk, Eric, Baratta, Jaime, Deiling, Brittany, Deschamps, Laura, Glick, Michael, Katz, Daniel, Krieg, James, Lessin, Jennifer, Torjman, Marc, Chin, Ki Jinn, Jin, Rongyu, Salpeter, Mary Jane, Powell, Mark, Simmons, Jeffrey, Lawson, Prentiss, Kukreja, Promil, Graves, Shanna, Sturdivant, Adam, Bryant, Ayesha, Crump, Sandra Joyce, Dillane, Derek, Taylor, Michael, Verrier, Michelle, Applegate, Richard, Arias, Ana, Pineiro, Natasha, Uppington, Jeffrey, Wolinsky, Phillip, Sappenfield, Joshua, Gunnett, Amy, Hagen, Jennifer, Harris, Sara, Hollen, Kevin, Holloway, Brian, Horodyski, Mary Beth, Pogue, Trevor, Ramani, Ramachandran, Smith, Cameron, Woods, Anna, Warrick, Matthew, Flynn, Kelly, Mongan, Paul, Ranganath, Yatish, Fernholz, Sean, Ingersoll-Weng, Esperanza, Marian, Anil, Seering, Melinda, Sibenaller, Zita, Stout, Lori, Wagner, Allison, Walter, Alicia, Wong, Cynthia, Magaziner, Jay, Orwig, Denise, Brown, Trina, Dattilo, Jim, Ellenberg, Susan, Feng, Rui, Fleisher, Lee, Gaskins, Lakisha, Goud, Maithri, Helker, Chris, Mezenghie, Lydia, Montgomery, Brittany, Preston, Peter, Stephens, Alisa, Schwartz, J. Sanford, Tierney, Ann, Weber, Ramona, Chelly, Jacques, Goel, Shiv, Goncz, Wende, Kawabe, Touichi, Khetarpal, Sharad, King, Kevin, Kunkel, Frank, Luke, Charles, Monroe, Amy, Shick, Vladislav, Silipo, Anthony, Stehle, Caroline, Szabo, Katherine, Yennam, Sudhakar, Hoeft, Mark, Breidenstein, Max, Dominick, Timothy, Friend, Alexander, Mathews, Donald, Lennertz, Richard, Akere, Helen, Balweg, Tyler, Bo, Amber, Doro, Christopher, Goodspeed, David, Lang, Gerald, Parker, Maggie, Rettammel, Amy, Roth, Mary, Sanders, Robert, White, Marissa, Whiting, Paul, Allen, Brian, Baker, Tracie, Craven, Debra, McEvoy, Matt, Turnbo, Teresa, Kates, Stephen, Morgan, Melanie, Willoughby, Teresa, Weigel, Wade, Auyong, David, Fox, Ellie, Welsh, Tina, Jaffe, J. Douglas, Cusson, Bruce, Dobson, Sean, Edwards, Christopher, Harris, Lynette, Henshaw, Daryl, Johnson, Kathleen, McKinney, Glen, Miller, Scott, Reynolds, Jon, Turner, Jimmy, VanEenenaam, David, Weller, Robert, Akhtar, Shamsuddin, Blessing, Marcelle, Johnson, Chanel, Kampp, Michael, Kunze, Kimberly, Li, Jinlei, O'Connor, Mary, Treggiari, Miriam, Hruslinski, Jennifer, Menio, Diane A., Hymes, Robert A., Langlois, Christine, Gaskins, Lakisha J., and Neuman, Mark D.

Published
2021
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14. Implementing Telemedicine During the COVID-19 Pandemic: Disparities in Utilization in an Urban Pain Medicine Practice

Author

Rockholt,Mika M, Addae,Gifty, Chee,Alexander, Chin,Wanda, Cuff,Germaine, Wang,Jing, Umeh,Uchenna O, Doan,Lisa V, Rockholt,Mika M, Addae,Gifty, Chee,Alexander, Chin,Wanda, Cuff,Germaine, Wang,Jing, Umeh,Uchenna O, and Doan,Lisa V

Abstract

Mika M Rockholt,1 Gifty Addae,1 Alexander Chee,1 Wanda Chin,1 Germaine Cuff,1 Jing Wang,1,2 Uchenna O Umeh,1,3 Lisa V Doan1 1Department of Anesthesiology, Perioperative Care and Pain Management, New York University Grossman School of Medicine, New York, NY, 10016, USA; 2Department of Neuroscience & Physiology, Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, 10016, USA; 3Department of Orthopedic Surgery, New York University Grossman School of Medicine, New York, NY, 10016, USACorrespondence: Mika M Rockholt, Department of Anesthesiology, Perioperative Care and Pain Medicine, New York University Grossman School of Medicine, New York, NY, 10016, USA, Tel +1 646-209-7590, Email Mika.Rockholt@nyulangone.orgPurpose: The COVID-19 pandemic led to a drastic expansion in utilizing telemedicine, circumventing some of the geographical barriers to accessing pain care. However, uncertainties around the impact of telemedicine across various sociodemographic groups still exist, prompting further exploration. Therefore, this study aimed to evaluate the impact of sociodemographic factors in telemedicine utilization during and after the COVID-19 pandemic.Patients and methods: All outpatient non-procedural visits at the pain medicine division of a large academic institution in the epicenter of the pandemic (New York, USA), between March 2019 and October 2021, were retrospectively included. Sociodemographic data including gender, age, ethnicity/race, postal code, and type of health insurance, across three time periods associated with the COVID-19 pandemic - pre-lockdown (in-office visits only), lockdown (telemedicine visits only) and post-lockdown (offering both in-office and telemedicine visits) – were analyzed and compared.Results: In total, 12,615 unique patients - The majority being women (58%) - were seen during the whole study period. In the post-lockdown period, telemedicine was utilized by 42% of all patients. Follow-up visits, younge

Published
2023

24. Engaging patients as partners in a multicentre trial of spinal versus general anaesthesia for older adults

Author

Hruslinski, Jennifer, primary, Menio, Diane A., additional, Hymes, Robert A., additional, Jaffe, J. Douglas, additional, Langlois, Christine, additional, Ramsey, Lolita, additional, Gaskins, Lakisha J., additional, Neuman, Mark D., additional, Looke, Thomas, additional, Bent, Sandra, additional, Franco-Mora, Ariana, additional, Hedrick, Pamela, additional, Newbern, Matthew, additional, Tadros, Rafik, additional, Pealer, Karen, additional, Marcantonio, Edward, additional, Vlassakov, Kamen, additional, Buckley, Carolyn, additional, Gorbatov, Svetlana, additional, Gosnell, James, additional, Steen, Talora, additional, Vafai, Avery, additional, Zeballos, Jose, additional, Cardenas, Louis, additional, Berry, Ashley, additional, Getchell, John, additional, Quercetti, Nicholas, additional, Sessler, Daniel I., additional, Ayad, Sabry, additional, Hassan, Manal, additional, Ali, Assad, additional, Bajracharya, Gauasan, additional, Billow, Damien, additional, Bloomfield, Michael, additional, Elliott, Kavita, additional, Hampton, Robert, additional, He, Linda, additional, Honar, Hooman, additional, Khoshknabi, Dilara, additional, Kim, Daniel, additional, Minko, Paul, additional, Morris, Adam, additional, Niazi, Azfar, additional, Nutcharoen, Tara, additional, Roberts, Jeffrey, additional, Saha, Partha, additional, Salih, Ahmed, additional, Skolaris, Alexis, additional, Stang, Taylor, additional, Strimbu, Victor, additional, Templeton, Jesse, additional, Volio, Andrew, additional, Wang, Jiayi, additional, Bolkus, Kelly, additional, DeAngelis, Matthew, additional, Dodson, Gregory, additional, Gerritsen, Jeffrey, additional, McEniry, Brian, additional, Mitrev, Ludmil, additional, Kwofie, Kwesi, additional, Bonazza, Flynn, additional, Lloyd, Vera, additional, Panek, Izabela, additional, Dabiri, Jared, additional, Chavez, Chris, additional, Craig, Jason, additional, Davidson, Todd, additional, Dietrichs, Chad, additional, Fleetwood, Cheryl, additional, Foley, Mike, additional, Getto, Chris, additional, Hailes, Susie, additional, Hermes, Sarah, additional, Hooper, Andy, additional, Koener, Greg, additional, Kohls, Kate, additional, Law, Leslie, additional, Lipp, Adam, additional, Losey, Allison, additional, Nelson, William, additional, Nieto, Mario, additional, Rogers, Pam, additional, Rutman, Steve, additional, Scales, Garrett, additional, Sebastian, Barbara, additional, Stanciu, Tom, additional, Lobel, Gregg, additional, Giampiccolo, Michelle, additional, Herman, Dara, additional, Kaufman, Margit, additional, Murphy, Bryan, additional, Pau, Clara, additional, Puzio, Thomas, additional, Veselsky, Marlene, additional, Stone, Trevor, additional, Apostle, Kelly, additional, Boyer, Dory, additional, Fan, Brenda Chen, additional, Lee, Susan, additional, Lemke, Mike, additional, Merchant, Richard, additional, Moola, Farhad, additional, Payne, Kyrsten, additional, Perey, Bertrand, additional, Viskontas, Darius, additional, Poler, Mark, additional, D'Antonio, Patricia, additional, Sheppard, Richard, additional, Abdullah, Amer, additional, Fish-Fuhrmann, Jamie, additional, Giska, Mark, additional, Fidkowski, Christina, additional, Guthrie, Trent, additional, Hakeos, William, additional, Hayes, Lillian, additional, Hoegler, Joseph, additional, Nowak, Katherine, additional, Hymes, Robert, additional, Beck, Jeffery, additional, Cuff, Jaslynn, additional, Gaski, Greg, additional, Haaser, Sharon, additional, Holzman, Michael, additional, Malekzadeh, A. Stephen, additional, Schulman, Jeff, additional, Schwartzbach, Cary, additional, Sieber, Frederick, additional, Azefor, Tangwan, additional, Brown, Charles, additional, Davani, Arman, additional, Jaberi, Mahmood, additional, Masear, Courtney, additional, Sharma, Balram, additional, Haider, Syed Basit, additional, Chungu, Carolyn, additional, Ebrahimi, Ali, additional, Fikry, Karim, additional, Gannon, Kerri, additional, Marcantonio, Andrew, additional, Pace, Meredith, additional, Sanders, David, additional, Clarke, Collin, additional, Lawendy, Abdel, additional, Schwartz, Gary, additional, Garg, Mohit, additional, Kim, Joseph, additional, Marshall, Mitchell, additional, Caurci, Juan, additional, Commeh, Ekow, additional, Cuevas, Randy, additional, Cuff, Germaine, additional, Franco, Lola, additional, Furguiele, David, additional, Giuca, Matthew, additional, Allman, Melissa, additional, Barzideh, Omid, additional, Cossaro, James, additional, D'Arduini, Armando, additional, Farhi, Anita, additional, Gould, Jason, additional, Kafel, John, additional, Patel, Anuj, additional, Peller, Abraham, additional, Reshef, Hadas, additional, Safur, Mohammed, additional, Toscano, Fiore, additional, Tedore, Tiffany, additional, Akerman, Michael, additional, Brumberger, Eric, additional, Clark, Sunday, additional, Friedlander, Rachel, additional, Jegarl, Anita, additional, Lane, Joseph, additional, Lyden, John P., additional, Mehta, Nili, additional, Murrell, Matthew T., additional, Painter, Nathan, additional, Ricci, William, additional, Sbrollini, Kaitlyn, additional, Sharma, Rahul, additional, Steel, Peter A.D., additional, Steinkamp, Michele, additional, Weinberg, Roniel, additional, Wellman, David Stephenson, additional, Nader, Antoun, additional, Fitzgerald, Paul, additional, Ritz, Michaela, additional, Papp, Steven, additional, Bryson, Greg, additional, Craig, Alexandra, additional, Farhat, Cassandra, additional, Gammon, Braden, additional, Gofton, Wade, additional, Harris, Nicole, additional, Lalonde, Karl, additional, Liew, Allan, additional, Meulenkamp, Bradley, additional, Sonnenburg, Kendra, additional, Wai, Eugene, additional, Wilkin, Geoffrey, additional, Donegan, Derek, additional, Dinh, Cassandra, additional, Elkassabany, Nabil, additional, Horan, Annamarie, additional, Mehta, Samir, additional, Troxell, Karen, additional, Alderfer, Mary Ellen, additional, Brannen, Jason, additional, Cupitt, Christopher, additional, Gerhart, Stacy, additional, McLin, Renee, additional, Sheidy, Julie, additional, Yurick, Katherine, additional, Carson, Jeffrey, additional, Chen, Fei, additional, Dragert, Karen, additional, Kiss, Geza, additional, Malveaux, Halina, additional, McCloskey, Deborah, additional, Mellender, Scott, additional, Mungekar, Sagar S., additional, Noveck, Helaine, additional, Sagebien, Carlos, additional, Perlman, Barry, additional, Biby, Luat, additional, McKelvy, Gail, additional, Richards, Anna, additional, Azim, Syed, additional, Abola, Ramon, additional, Ayala, Brittney, additional, Halper, Darcy, additional, Mavarez, Ana, additional, Choi, Stephen, additional, Awad, Imad, additional, Flynn, Brendan, additional, Henry, Patrick, additional, Jenkinson, Richard, additional, Kaustov, Lilia, additional, Lappin, Elizabeth, additional, McHardy, Paul, additional, Singh, Amara, additional, Hauck, Ellen, additional, Donnelly, Joanne, additional, Gonzalez, Meera, additional, Haydel, Christopher, additional, Livelsberger, Jon, additional, Pazionis, Theresa, additional, Slattery, Bridget, additional, Vazquez-Trejo, Maritza, additional, Schwenk, Eric, additional, Baratta, Jaime, additional, Deiling, Brittany, additional, Deschamps, Laura, additional, Glick, Michael, additional, Katz, Daniel, additional, Krieg, James, additional, Lessin, Jennifer, additional, Torjman, Marc, additional, Chin, Ki Jinn, additional, Jin, Rongyu, additional, Salpeter, Mary Jane, additional, Powell, Mark, additional, Simmons, Jeffrey, additional, Lawson, Prentiss, additional, Kukreja, Promil, additional, Graves, Shanna, additional, Sturdivant, Adam, additional, Bryant, Ayesha, additional, Crump, Sandra Joyce, additional, Dillane, Derek, additional, Taylor, Michael, additional, Verrier, Michelle, additional, Applegate, Richard, additional, Arias, Ana, additional, Pineiro, Natasha, additional, Uppington, Jeffrey, additional, Wolinsky, Phillip, additional, Sappenfield, Joshua, additional, Gunnett, Amy, additional, Hagen, Jennifer, additional, Harris, Sara, additional, Hollen, Kevin, additional, Holloway, Brian, additional, Horodyski, Mary Beth, additional, Pogue, Trevor, additional, Ramani, Ramachandran, additional, Smith, Cameron, additional, Woods, Anna, additional, Warrick, Matthew, additional, Flynn, Kelly, additional, Mongan, Paul, additional, Ranganath, Yatish, additional, Fernholz, Sean, additional, Ingersoll-Weng, Esperanza, additional, Marian, Anil, additional, Seering, Melinda, additional, Sibenaller, Zita, additional, Stout, Lori, additional, Wagner, Allison, additional, Walter, Alicia, additional, Wong, Cynthia, additional, Magaziner, Jay, additional, Orwig, Denise, additional, Brown, Trina, additional, Dattilo, Jim, additional, Ellenberg, Susan, additional, Feng, Rui, additional, Fleisher, Lee, additional, Gaskins, Lakisha, additional, Goud, Maithri, additional, Helker, Chris, additional, Mezenghie, Lydia, additional, Montgomery, Brittany, additional, Preston, Peter, additional, Stephens, Alisa, additional, Schwartz, J. Sanford, additional, Tierney, Ann, additional, Weber, Ramona, additional, Chelly, Jacques, additional, Goel, Shiv, additional, Goncz, Wende, additional, Kawabe, Touichi, additional, Khetarpal, Sharad, additional, King, Kevin, additional, Kunkel, Frank, additional, Luke, Charles, additional, Monroe, Amy, additional, Shick, Vladislav, additional, Silipo, Anthony, additional, Stehle, Caroline, additional, Szabo, Katherine, additional, Yennam, Sudhakar, additional, Hoeft, Mark, additional, Breidenstein, Max, additional, Dominick, Timothy, additional, Friend, Alexander, additional, Mathews, Donald, additional, Lennertz, Richard, additional, Akere, Helen, additional, Balweg, Tyler, additional, Bo, Amber, additional, Doro, Christopher, additional, Goodspeed, David, additional, Lang, Gerald, additional, Parker, Maggie, additional, Rettammel, Amy, additional, Roth, Mary, additional, Sanders, Robert, additional, White, Marissa, additional, Whiting, Paul, additional, Allen, Brian, additional, Baker, Tracie, additional, Craven, Debra, additional, McEvoy, Matt, additional, Turnbo, Teresa, additional, Kates, Stephen, additional, Morgan, Melanie, additional, Willoughby, Teresa, additional, Weigel, Wade, additional, Auyong, David, additional, Fox, Ellie, additional, Welsh, Tina, additional, Cusson, Bruce, additional, Dobson, Sean, additional, Edwards, Christopher, additional, Harris, Lynette, additional, Henshaw, Daryl, additional, Johnson, Kathleen, additional, McKinney, Glen, additional, Miller, Scott, additional, Reynolds, Jon, additional, Turner, Jimmy, additional, VanEenenaam, David, additional, Weller, Robert, additional, Akhtar, Shamsuddin, additional, Blessing, Marcelle, additional, Johnson, Chanel, additional, Kampp, Michael, additional, Kunze, Kimberly, additional, Li, Jinlei, additional, O'Connor, Mary, additional, and Treggiari, Miriam, additional

Published
2021
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31. Risk of Epidural Hematoma after Neuraxial Techniques in Thrombocytopenic Parturients : A Report from the Multicenter Perioperative Outcomes Group

Author

Lee, Linden O., Bateman, Brian T., Kheterpal, Sachin, Klumpner, Thomas T., Housey, Michelle, Aziz, Michael F., Hand, Karen W., MacEachern, Mark, Goodier, Christopher G., Bernstein, Jeffrey, Bauer, Melissa E., Lirk, Philip, Wilczak, Janet, Soto, Roy, Tom, Simon, Cuff, Germaine, Biggs, Daniel A., Coffman, Traci, Saager, Leif, Levy, Warren J., Godbold, Michael, Pace, Nathan L., Wethington, Kevin L., Paganelli, William C., Durieux, Marcel E., Domino, Karen B., Nair, Bala, Ehrenfeld, Jesse M., Wanderer, Jonathan P., Schonberger, Robert B., Berris, Joshua, Lins, Steven, Coles, Peter, Cummings, Kenneth C., Maheshwari, Kamal, Berman, Mitchell F., Wedeven, Christopher, LaGorio, John, Fleishut, Peter M., Ellis, Terri A., Molina, Susan, Carl, Curtis, Kadry, Bassam, van Klei, Wilton A A, Pasma, Wietze, Jameson, Leslie C., Helsten, Daniel L., and Avidan, Michael S.

Subjects
Multicenter Study, Anesthesiology and Pain Medicine, Journal Article, Observational Study
Abstract

BACKGROUND:: Thrombocytopenia has been considered a relative or even absolute contraindication to neuraxial techniques due to the risk of epidural hematoma. There is limited literature to estimate the risk of epidural hematoma in thrombocytopenic parturients. The authors reviewed a large perioperative database and performed a systematic review to further define the risk of epidural hematoma requiring surgical decompression in this population. METHODS:: The authors performed a retrospective cohort study using the Multicenter Perioperative Outcomes Group database to identify thrombocytopenic parturients who received a neuraxial technique and to estimate the risk of epidural hematoma. Patients were stratified by platelet count, and those requiring surgical decompression were identified. A systematic review was performed, and risk estimates were combined with those from the existing literature. RESULTS:: A total of 573 parturients with a platelet count less than 100,000 mm who received a neuraxial technique across 14 institutions were identified in the Multicenter Perioperative Outcomes Group database, and a total of 1,524 parturients were identified after combining the data from the systematic review. No cases of epidural hematoma requiring surgical decompression were observed. The upper bound of the 95% CI for the risk of epidural hematoma for a platelet count of 0 to 49,000 mm is 11%, for 50,000 to 69,000 mm is 3%, and for 70,000 to 100,000 mm is 0.2%. CONCLUSIONS:: The number of thrombocytopenic parturients in the literature who received neuraxial techniques without complication has been significantly increased. The risk of epidural hematoma associated with neuraxial techniques in parturients at a platelet count less than 70,000 mm remains poorly defined due to limited observations.

Published
2017

33. DELAYED ATTAINMENT OF PHYSICAL THERAPY MILESTONES WITH THE ADDITION OF AN ADDUCTOR CANAL BLOCK TO LOCAL INFILTRATION ANALGESIA FOLLOWING TOTAL KNEE ARTHROPLASTY

Author

Cuff, Germaine

Abstract

Background and Goal of Study: Retrospective data, prior studies and a recent meta-analysis suggest a synergistic analgesic effect of an Adductor Canal Blockade (ACB) added to Local Infiltration Analgesia (LIA) compared to LIA alone following Total Knee Arthroplasty (TKA). Our hypothesis was therefore that Physical Therapy (PT) milestones would be reached faster with ACB + LIA than LIA alone.Materials and Methods: After IRB approval, patients scheduled for unilateral primary TKA were randomized to receive either ACB or a sham block (saline) in addition to the LIA administered by the surgeon. Exclusion criteria included significant systemic disease, substance abuse and chronic pain. Spinal anesthetic and postoperative pain management were standardized. ACB was performed at the mid-thigh level with 30 mL of 0.25% bupivacaine with 1:200,000 adrenaline. LIA was performed by the surgeon using bupivacaine, ketorolac, adrenaline and morphine, as well as liposomal bupivacaine.Data collected included passive and active ROM of the knee in flexion and extension; quadriceps strength; bed mobility skill: transfer skill; 2-minute walk test; total distance ambulated on the day of surgery and the first and second post-operative days; ability to climb stairs; readiness for discharge; and pain complaints by NVS before, during and after physical therapy sessions.Results: Preliminary results of 63 patients out of 150 planned are reported. Pain scores, measured as an AUC for the initial 48 hours, were not different between groups (186 u00b1 71 vs. 187 u00b1 80). However, total distances ambulated and 2-minute walk tests suggested that the group that received the ACB in addition to LIA achieved less on PT at each of the time points than the group that received LIA alone (total distances ambulated: DOS: 104 u00b1 90 vs. 137 u00b1 89 ft; POD1 am: 150 u00b1 106 vs. 249 u00b1 152 ft; POD1 pm: 142 u00b1 110 vs. 183 u00b1 92 ft; POD2 am: 135 u00b1 124 vs. 210 u00b1 36 ft; 2-minute walk test: DOS: 56 u00b1 50 vs. 76 u00b1 60 ft; POD1 am: 80 u00b1 71 vs. 129 u00b1 121 ft; POD1 pm: 78 u00b1 66 vs. 118 u00b1 65 ft; POD2 am: 80 u00b1 65 vs. 152 u00b1 75 ft).Discussion: While these interim results remain to be confirmed, the data suggest that LIA alone is preferable to LIA + ACB, providing similar pain control with earlier achievement of physical therapy milestones.

Published
2017

34. In Reply

Author

Blitz, Jeanna D., primary, Kendale, Samir M., additional, Jain, Sudheer K., additional, Cuff, Germaine E., additional, Kim, Jung T., additional, and Rosenberg, Andrew D., additional

Published
2017
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35. Risk of Epidural Hematoma after Neuraxial Techniques in Thrombocytopenic Parturients: A Report from the Multicenter Perioperative Outcomes Group

Author

Medische staf Anesthesiologie, Circulatory Health, Management Vitale Functies, Trialbureau Vitale Functies, Lee, Linden O., Bateman, Brian T., Kheterpal, Sachin, Klumpner, Thomas T., Housey, Michelle, Aziz, Michael F., Hand, Karen W., MacEachern, Mark, Goodier, Christopher G., Bernstein, Jeffrey, Bauer, Melissa E., Lirk, Philip, Wilczak, Janet, Soto, Roy, Tom, Simon, Cuff, Germaine, Biggs, Daniel A., Coffman, Traci, Saager, Leif, Levy, Warren J., Godbold, Michael, Pace, Nathan L., Wethington, Kevin L., Paganelli, William C., Durieux, Marcel E., Domino, Karen B., Nair, Bala, Ehrenfeld, Jesse M., Wanderer, Jonathan P., Schonberger, Robert B., Berris, Joshua, Lins, Steven, Coles, Peter, Cummings, Kenneth C., Maheshwari, Kamal, Berman, Mitchell F., Wedeven, Christopher, LaGorio, John, Fleishut, Peter M., Ellis, Terri A., Molina, Susan, Carl, Curtis, Kadry, Bassam, van Klei, Wilton A A, Pasma, Wietze, Jameson, Leslie C., Helsten, Daniel L., Avidan, Michael S., Medische staf Anesthesiologie, Circulatory Health, Management Vitale Functies, Trialbureau Vitale Functies, Lee, Linden O., Bateman, Brian T., Kheterpal, Sachin, Klumpner, Thomas T., Housey, Michelle, Aziz, Michael F., Hand, Karen W., MacEachern, Mark, Goodier, Christopher G., Bernstein, Jeffrey, Bauer, Melissa E., Lirk, Philip, Wilczak, Janet, Soto, Roy, Tom, Simon, Cuff, Germaine, Biggs, Daniel A., Coffman, Traci, Saager, Leif, Levy, Warren J., Godbold, Michael, Pace, Nathan L., Wethington, Kevin L., Paganelli, William C., Durieux, Marcel E., Domino, Karen B., Nair, Bala, Ehrenfeld, Jesse M., Wanderer, Jonathan P., Schonberger, Robert B., Berris, Joshua, Lins, Steven, Coles, Peter, Cummings, Kenneth C., Maheshwari, Kamal, Berman, Mitchell F., Wedeven, Christopher, LaGorio, John, Fleishut, Peter M., Ellis, Terri A., Molina, Susan, Carl, Curtis, Kadry, Bassam, van Klei, Wilton A A, Pasma, Wietze, Jameson, Leslie C., Helsten, Daniel L., and Avidan, Michael S.

Published
2017

38. Effects of a single subanaesthetic dose of ketamine on pain and mood after laparoscopic bariatric surgery.

Author

Jing Wang, Echevarria, Ghislaine C., Doan, Lisa, Ekasumara, Nydia, Calvino, Steven, Chae, Floria, Martinez, Erik, Robinson, Eric, Cuff, Germaine, Franco, Lola, Muntyan, Igor, Kurian, Marina, Schwack, Bradley F., Bedrosian, Andrea S., Fielding, George A., and Ren-Fielding, Christine J.

Abstract

BACKGROUND When administered as a continuous infusion, ketamine is known to be a potent analgesic and general anaesthetic. Recent studies suggest that a single low-dose administration of ketamine can provide a long-lasting effect on mood, but its effects when given in the postoperative period have not been studied. OBJECTIVE We hypothesised that a single low-dose administration of ketamine after bariatric surgery can improve pain and mood scores in the immediate postoperative period. DESIGN We performed a randomised, double-blind, placebo-controlled study to compare a single subanaesthetic dose of ketamine (0.4 mg kg-1) with a normal saline placebo in the postanaesthesia care unit after laparoscopic gastric bypass and gastrectomy. SETTING Single-centre, tertiary care hospital, October 2014 to January 2018. PATIENTS A total of 100 patients were randomised into the ketamine and saline groups. INTERVENTION Patients in the ketamine group received a single dose of ketamine infusion (0.4 mg kg-1) in the postanaesthesia care unit. Patients in the placebo groups received 0.9% saline. OUTCOME MEASURES The primary outcome was the visual analogue pain score. A secondary outcome was performance on the short-form McGill's Pain Questionnaire (SF-MPQ). RESULTS There were no significant differences in visual analogue pain scores between groups (group-by-time interaction P=0.966; marginal group effect P=0.137). However, scores on the affective scale of SF-MPQ (secondary outcome) significantly decreased in the ketamine group as early as postoperative day (POD) 2 [mean difference = -2.2 (95% bootstrap CI -2.9 to 1.6), Bonferroni adjusted P<0.001], compared with placebo group in which the scores decreased only by POD 7. Scores on the total scale of SF-MPQ for the ketamine group were smaller compared with the placebo group (P=0.034). CONCLUSION Although there was no significant difference between ketamine and placebo for the primary outcome measure, patients who received ketamine experienced statistically and clinically significant improvement in their comprehensive evaluation of pain, particularly the affective component of pain, on POD 2. However, future studies are needed to confirm the enduring effects of ketamine on the affective response to postoperative pain. [ABSTRACT FROM AUTHOR]

Published
2019
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39. Étude rétrospective des schémas de prescription d’opioïdes au congé de l’hôpital chez les patients chirurgicaux ayant un syndrome d’apnée-hypopnée du sommeil.

Author

Kendale, Samir M., Wang, Jing, Blitz, Jeanna D., Calvino, Steven, Cuff, Germaine, Barone, Nicholas, Rosenberg, Andrew D., and Doan, Lisa

Abstract

Purpose: Obstructive sleep apnea (OSA) is a risk factor for complications with postoperative opioid use, and in those patients with known or suspected OSA, minimization of postoperative opioids is recommended. We hypothesize that despite these recommendations, surgical patients with known or suspected OSA are prescribed postoperative opioids at hospital discharge at similar doses to those without OSA.Methods: This was a retrospective analysis of the electronic health records of surgical patients from 1 November 2016 to 30 April 2017 at a single academic institution. Patients with a known diagnosis of OSA or a STOP-Bang score ≥ 5 were compared with those without OSA for the amount of postoperative discharge opioid medication using multivariable linear regression.Results: Of the 17,671 patients analyzed, 1,692 (9.6%) had known or suspected OSA with 1,450 (86%) of these patients discharged on opioid medications. Of the 15,979 patients without OSA, 12,273 (77%) were discharged on opioid medications. The total median [interquartile range (IQR)] oral morphine equivalents (OME) for all patients was 150 [0-338] mg and for patients with known or suspected OSA was 160 [0-450] mg, an unadjusted comparison showing an 18% difference in OME (95% confidence interval [CI], 3% to 35%; P = 0.02). The analysis, after adjusting for confounders, showed no significant difference in the amount of opioids prescribed to OSA or non-OSA patients (8% difference in total OME; 95% CI, -6% to 25%; P = 0.26).Conclusion: This study shows that surgical patients at risk for OSA or confirmed OSA are prescribed opioids at similar rates and doses upon discharge despite guidelines that recommend minimizing opioid use in OSA patients. These findings indicate a need to implement different strategies to reduce the prescription of opioids to patients with OSA. [ABSTRACT FROM AUTHOR]

Published
2018
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42. Brachial Plexus Blockade Causes Subclinical Neuropathy: A Prospective Observational Study.

Author

Perretta, Donato J., Gotlin, Matthew, Brock, Kenneth, Paksima, Nader, Gottschalk, Michael B., Cuff, Germaine, Rettig, Michael, and Atchabahian, Arthur

Abstract

Background: The objective of this study is to determine subclinical changes in hand sensation after brachial plexus blocks used for hand surgery procedures. We used Semmes-Weinstein monofilament testing to detect these changes. We hypothesized that patients undergoing brachial plexus nerve blocks would have postoperative subclinical neuropathy detected by monofilament testing when compared with controls. Methods: In total, 115 hand surgery adult patients were prospectively enrolled in this study. All patients undergoing nerve-related procedures were excluded as well as any patients with preoperative clinically apparent nerve deficits. Eighty-four patients underwent brachial plexus blockade preoperatively, and 31 patients underwent general anesthesia (GA). Semmes-Weinstein monofilament testing of the hand was performed preoperatively on both the operative and nonoperative extremities and postoperatively at a mean of 11 days on both hands. Preoperative and postoperative monofilament testing scores were compared between the block hand and the nonoperated hand of the same patient, as well as between the block hands and the GA-operated hands. Results: There were no recorded clinically relevant neurologic complications in the block group or GA group. A statistically significant decrease in sensation in postoperative testing in the operated block hand compared with the nonoperated hand was noted. When comparing the operated block hand with the operated GA hand, there was a decrease in postoperative sensation in the operated block hand that did not reach statistical significance. Conclusions: Brachial plexus blockade causes subtle subclinical decreases in sensibility at short-term follow-up, without any clinically relevant manifestations. [ABSTRACT FROM AUTHOR]

Published
2017
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50. Pain, Analgesic Use, and Patient Satisfaction With Spinal Versus General Anesthesia for Hip Fracture Surgery : A Randomized Clinical Trial.

Author

Neuman MD, Feng R, Ellenberg SS, Sieber F, Sessler DI, Magaziner J, Elkassabany N, Schwenk ES, Dillane D, Marcantonio ER, Menio D, Ayad S, Hassan M, Stone T, Papp S, Donegan D, Marshall M, Jaffe JD, Luke C, Sharma B, Azim S, Hymes R, Chin KJ, Sheppard R, Perlman B, Sappenfield J, Hauck E, Hoeft MA, Tierney A, Gaskins LJ, Horan AD, Brown T, Dattilo J, Carson JL, Looke T, Bent S, Franco-Mora A, Hedrick P, Newbern M, Tadros R, Pealer K, Vlassakov K, Buckley C, Gavin L, Gorbatov S, Gosnell J, Steen T, Vafai A, Zeballos J, Hruslinski J, Cardenas L, Berry A, Getchell J, Quercetti N, Bajracharya G, Billow D, Bloomfield M, Cuko E, Elyaderani MK, Hampton R, Honar H, Khoshknabi D, Kim D, Krahe D, Lew MM, Maheshwer CB, Niazi A, Saha P, Salih A, de Swart RJ, Volio A, Bolkus K, DeAngelis M, Dodson G, Gerritsen J, McEniry B, Mitrev L, Kwofie MK, Belliveau A, Bonazza F, Lloyd V, Panek I, Dabiri J, Chavez C, Craig J, Davidson T, Dietrichs C, Fleetwood C, Foley M, Getto C, Hailes S, Hermes S, Hooper A, Koener G, Kohls K, Law L, Lipp A, Losey A, Nelson W, Nieto M, Rogers P, Rutman S, Scales G, Sebastian B, Stanciu T, Lobel G, Giampiccolo M, Herman D, Kaufman M, Murphy B, Pau C, Puzio T, Veselsky M, Apostle K, Boyer D, Fan BC, Lee S, Lemke M, Merchant R, Moola F, Payne K, Perey B, Viskontas D, Poler M, D'Antonio P, O'Neill G, Abdullah A, Fish-Fuhrmann J, Giska M, Fidkowski C, Guthrie ST, Hakeos W, Hayes L, Hoegler J, Nowak K, Beck J, Cuff J, Gaski G, Haaser S, Holzman M, Malekzadeh AS, Ramsey L, Schulman J, Schwartzbach C, Azefor T, Davani A, Jaberi M, Masear C, Haider SB, Chungu C, Ebrahimi A, Fikry K, Marcantonio A, Shelvan A, Sanders D, Clarke C, Lawendy A, Schwartz G, Garg M, Kim J, Caruci J, Commeh E, Cuevas R, Cuff G, Franco L, Furgiuele D, Giuca M, Allman M, Barzideh O, Cossaro J, D'Arduini A, Farhi A, Gould J, Kafel J, Patel A, Peller A, Reshef H, Safur M, Toscano F, Tedore T, Akerman M, Brumberger E, Clark S, Friedlander R, Jegarl A, Lane J, Lyden JP, Mehta N, Murrell MT, Painter N, Ricci W, Sbrollini K, Sharma R, Steel PAD, Steinkamp M, Weinberg R, Wellman DS, Nader A, Fitzgerald P, Ritz M, Bryson G, Craig A, Farhat C, Gammon B, Gofton W, Harris N, Lalonde K, Liew A, Meulenkamp B, Sonnenburg K, Wai E, Wilkin G, Troxell K, Alderfer ME, Brannen J, Cupitt C, Gerhart S, McLin R, Sheidy J, Yurick K, Chen F, Dragert K, Kiss G, Malveaux H, McCloskey D, Mellender S, Mungekar SS, Noveck H, Sagebien C, Biby L, McKelvy G, Richards A, Abola R, Ayala B, Halper D, Mavarez A, Rizwan S, Choi S, Awad I, Flynn B, Henry P, Jenkinson R, Kaustov L, Lappin E, McHardy P, Singh A, Donnelly J, Gonzalez M, Haydel C, Livelsberger J, Pazionis T, Slattery B, Vazquez-Trejo M, Baratta J, Cirullo M, Deiling B, Deschamps L, Glick M, Katz D, Krieg J, Lessin J, Mojica J, Torjman M, Jin R, Salpeter MJ, Powell M, Simmons J, Lawson P, Kukreja P, Graves S, Sturdivant A, Bryant A, Crump SJ, Verrier M, Green J, Menon M, Applegate R, Arias A, Pineiro N, Uppington J, Wolinsky P, Gunnett A, Hagen J, Harris S, Hollen K, Holloway B, Horodyski MB, Pogue T, Ramani R, Smith C, Woods A, Warrick M, Flynn K, Mongan P, Ranganath Y, Fernholz S, Ingersoll-Weng E, Marian A, Seering M, Sibenaller Z, Stout L, Wagner A, Walter A, Wong C, Orwig D, Goud M, Helker C, Mezenghie L, Montgomery B, Preston P, Schwartz JS, Weber R, Fleisher LA, Mehta S, Stephens-Shields AJ, Dinh C, Chelly JE, Goel S, Goncz W, Kawabe T, Khetarpal S, Monroe A, Shick V, Breidenstein M, Dominick T, Friend A, Mathews D, Lennertz R, Sanders R, Akere H, Balweg T, Bo A, Doro C, Goodspeed D, Lang G, Parker M, Rettammel A, Roth M, White M, Whiting P, Allen BFS, Baker T, Craven D, McEvoy M, Turnbo T, Kates S, Morgan M, Willoughby T, Weigel W, Auyong D, Fox E, Welsh T, Cusson B, Dobson S, Edwards C, Harris L, Henshaw D, Johnson K, McKinney G, Miller S, Reynolds J, Segal BS, Turner J, VanEenenaam D, Weller R, Lei J, Treggiari M, Akhtar S, Blessing M, Johnson C, Kampp M, Kunze K, O'Connor M, Looke T, Tadros R, Vlassakov K, Cardenas L, Bolkus K, Mitrev L, Kwofie MK, Dabiri J, Lobel G, Poler M, Giska M, Sanders D, Schwartz G, Giuca M, Tedore T, Nader A, Bryson G, Troxell K, Kiss G, Choi S, Powell M, Applegate R, Warrick M, Ranganath Y, Chelly JE, Lennertz R, Sanders R, Allen BFS, Kates S, Weigel W, Li J, Wijeysundera DN, Kheterpal S, Moore RH, Smith AK, Tosi LL, Looke T, Mehta S, Fleisher L, Hruslinski J, Ramsey L, Langlois C, Mezenghie L, Montgomery B, Oduwole S, and Rose T

Subjects
Aged, Analgesics therapeutic use, Anesthesia, General adverse effects, Canada, Female, Humans, Male, Pain, Pain, Postoperative drug therapy, Patient Satisfaction, Anesthesia, Spinal adverse effects, Hip Fractures surgery
Abstract

Background: The REGAIN (Regional versus General Anesthesia for Promoting Independence after Hip Fracture) trial found similar ambulation and survival at 60 days with spinal versus general anesthesia for hip fracture surgery. Trial outcomes evaluating pain, prescription analgesic use, and patient satisfaction have not yet been reported., Objective: To compare pain, analgesic use, and satisfaction after hip fracture surgery with spinal versus general anesthesia., Design: Preplanned secondary analysis of a pragmatic randomized trial. (ClinicalTrials.gov: NCT02507505)., Setting: 46 U.S. and Canadian hospitals., Participants: Patients aged 50 years or older undergoing hip fracture surgery., Intervention: Spinal or general anesthesia., Measurements: Pain on postoperative days 1 through 3; 60-, 180-, and 365-day pain and prescription analgesic use; and satisfaction with care., Results: A total of 1600 patients were enrolled. The average age was 78 years, and 77% were women. A total of 73.5% (1050 of 1428) of patients reported severe pain during the first 24 hours after surgery. Worst pain over the first 24 hours after surgery was greater with spinal anesthesia (rated from 0 [no pain] to 10 [worst pain imaginable]; mean difference, 0.40 [95% CI, 0.12 to 0.68]). Pain did not differ across groups at other time points. Prescription analgesic use at 60 days occurred in 25% (141 of 563) and 18.8% (108 of 574) of patients assigned to spinal and general anesthesia, respectively (relative risk, 1.33 [CI, 1.06 to 1.65]). Satisfaction was similar across groups., Limitation: Missing outcome data and multiple outcomes assessed., Conclusion: Severe pain is common after hip fracture. Spinal anesthesia was associated with more pain in the first 24 hours after surgery and more prescription analgesic use at 60 days compared with general anesthesia., Primary Funding Source: Patient-Centered Outcomes Research Institute .

Published
2022
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