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1. Organization and Activity of Italian Echocardiographic Laboratories: A Survey of the Italian Society of Echocardiography and Cardiovascular Imaging

Author

Ciampi, Q, Pepi, M, Antonini-Canterin, F, Barbieri, A, Barchitta, A, Faganello, G, Miceli, S, Parato, V, Tota, A, Trocino, G, Abbate, M, Accadia, M, Alemanni, R, Angelini, A, Anglano, F, Anselmi, M, Aquila, I, Aramu, S, Avogadri, E, Azzaro, G, Badano, L, Balducci, A, Ballocca, F, Barbarossa, A, Barbati, G, Barletta, V, Barone, D, Becherini, F, Benfari, G, Beraldi, M, Bergandi, G, Bilardo, G, Binno, S, Bolognesi, M, Bongiovi, S, Bragato, R, Braggion, G, Brancaleoni, R, Bursi, F, Dessalvi, C, Cameli, M, Canu, A, Capitelli, M, Capra, A, Carbonara, R, Carbone, M, Carbonella, M, Carrabba, N, Casavecchia, G, Casula, M, Chesi, E, Cicco, S, Citro, R, Cocchia, R, Colombo, B, Colonna, P, Conte, M, Corrado, G, Cortesi, P, Cortigiani, L, Costantino, M, Cozza, F, Cucchini, U, D'Angelo, M, Ros, S, D'Andrea, F, D'Andrea, A, D'Auria, F, De Caridi, G, De Feo, S, De Matteis, G, De Vecchi, S, Del Giudice, C, Dell'Angela, L, Delli Paoli, L, Dentamaro, I, Destefanis, P, Di Fulvio, M, Di Gaetano, R, Di Giannuario, G, Di Gioia, A, Di Martino, L, Di Muro, C, Di Nora, C, Di Salvo, G, Dodi, C, Dogliani, S, Donati, F, Dottori, M, Epifani, G, Fabiani, I, Ferrara, F, Ferrara, L, Ferrua, S, Filice, G, Fiorino, M, Forno, D, Garini, A, Giarratana, G, Gigantino, G, Giorgi, M, Giubertoni, E, Greco, C, Grigolato, M, Marra, W, Holzl, A, Iaiza, A, Iannaccone, A, Ilardi, F, Imbalzano, E, Inciardi, R, Inserra, C, Iori, E, Izzo, A, La Rosa, G, Labanti, G, Lanzone, A, Lanzoni, L, Lapetina, O, Leiballi, E, Librera, M, Lo Conte, C, Lo Monaco, M, Lombardo, A, Luciani, M, Lusardi, P, Magnante, A, Malagoli, A, Malatesta, G, Mancusi, C, Manes, M, Manganelli, F, Mantovani, F, Manuppelli, V, Marchese, V, Marinacci, L, Mattioli, R, Maurizio, C, Mazza, G, Mazza, S, Melis, M, Meloni, G, Merli, E, Milan, A, Minardi, G, Monaco, A, Monte, I, Montresor, G, Moreo, A, Mori, F, Morini, S, Moro, C, Morrone, D, Negri, F, Nipote, C, Nisi, F, Nocco, S, Novello, L, Nunziata, L, Perini, A, Parodi, A, Pasanisi, E, Pastorini, G, Pavasini, R, Pavoni, D, Pedone, C, Pelliccia, F, Pelliciari, G, Pelloni, E, Pergola, V, Perillo, G, Petruccelli, E, Pezzullo, C, Piacentini, G, Picardi, E, Pinna, G, Pizzarelli, M, Pizzuti, A, Poggi, M, Posteraro, A, Privitera, C, Rampazzo, D, Ratti, C, Rettegno, S, Ricci, F, Ricci, C, Rolando, C, Rossi, S, Rovera, C, Ruggieri, R, Russo, M, Sacchi, N, Saladino, A, Sani, F, Sartori, C, Scarabeo, V, Sciacqua, A, Scillone, A, Scopelliti, P, Scorza, A, Scozzafava, A, Serafini, F, Serra, W, Severino, S, Simeone, B, Sirico, D, Solari, M, Spadaro, G, Stefani, L, Strangio, A, Surace, F, Tamborini, G, Tarquinio, N, Tassone, E, Tavarozzi, I, Tchana, B, Tedesco, G, Tinto, M, Torzillo, D, Totaro, A, Triolo, O, Troisi, F, Tusa, M, Vancheri, F, Varasano, V, Venezia, A, Vermi, A, Villari, B, Zampi, G, Zannoni, J, Zito, C, Zugaro, A, Di Bella, G, Carerj, S, Ciampi Q., Pepi M., Antonini-Canterin F., Barbieri A., Barchitta A., Faganello G., Miceli S., Parato V. M., Tota A., Trocino G., Abbate M., Accadia M., Alemanni R., Angelini A., Anglano F., Anselmi M., Aquila I., Aramu S., Avogadri E., Azzaro G., Badano L., Balducci A., Ballocca F., Barbarossa A., Barbati G., Barletta V., Barone D., Becherini F., Benfari G., Beraldi M., Bergandi G., Bilardo G., Binno S. M., Bolognesi M., Bongiovi S., Bragato R. M., Braggion G., Brancaleoni R., Bursi F., Dessalvi C. C., Cameli M., Canu A., Capitelli M., Capra A. C. M., Carbonara R., Carbone M., Carbonella M., Carrabba N., Casavecchia G., Casula M., Chesi E., Cicco S., Citro R., Cocchia R., Colombo B. M., Colonna P., Conte M., Corrado G., Cortesi P., Cortigiani L., Costantino M. F., Cozza F., Cucchini U., D'Angelo M., Ros S. D., D'Andrea F., D'Andrea A., D'Auria F., De Caridi G., De Feo S., De Matteis G. M., De Vecchi S., Del Giudice C., Dell'Angela L., Delli Paoli L., Dentamaro I., Destefanis P., Di Fulvio M., Di Gaetano R., Di Giannuario G., Di Gioia A., Di Martino L. F. M., Di Muro C., Di Nora C., Di Salvo G., Dodi C., Dogliani S., Donati F., Dottori M., Epifani G., Fabiani I., Ferrara F., Ferrara L., Ferrua S., Filice G., Fiorino M., Forno D., Garini A., Giarratana G. A., Gigantino G., Giorgi M., Giubertoni E., Greco C. A., Grigolato M., Marra W. G., Holzl A., Iaiza A., Iannaccone A., Ilardi F., Imbalzano E., Inciardi R., Inserra C. A., Iori E., Izzo A., La Rosa G., Labanti G., Lanzone A. M., Lanzoni L., Lapetina O., Leiballi E., Librera M., Lo Conte C., Lo Monaco M., Lombardo A., Luciani M., Lusardi P., Magnante A., Malagoli A., Malatesta G., Mancusi C., Manes M. T., Manganelli F., Mantovani F., Manuppelli V., Marchese V., Marinacci L., Mattioli R., Maurizio C., Mazza G. A., Mazza S., Melis M., Meloni G., Merli E., Milan A., Minardi G., Monaco A., Monte I., Montresor G., Moreo A., Mori F., Morini S., Moro C., Morrone D., Negri F., Nipote C., Nisi F., Nocco S., Novello L., Nunziata L., Perini A. P., Parodi A., Pasanisi E. M., Pastorini G., Pavasini R., Pavoni D., Pedone C., Pelliccia F., Pelliciari G., Pelloni E., Pergola V., Perillo G., Petruccelli E., Pezzullo C., Piacentini G., Picardi E., Pinna G., Pizzarelli M., Pizzuti A., Poggi M. M., Posteraro A., Privitera C., Rampazzo D., Ratti C., Rettegno S., Ricci F., Ricci C., Rolando C., Rossi S., Rovera C., Ruggieri R., Russo M. G., Sacchi N., Saladino A., Sani F., Sartori C., Scarabeo V., Sciacqua A., Scillone A., Scopelliti P. A., Scorza A., Scozzafava A., Serafini F., Serra W., Severino S., Simeone B., Sirico D., Solari M., Spadaro G. L., Stefani L., Strangio A., Surace F. C., Tamborini G., Tarquinio N., Tassone E. J., Tavarozzi I., Tchana B., Tedesco G., Tinto M., Torzillo D., Totaro A., Triolo O. F., Troisi F., Tusa M., Vancheri F., Varasano V., Venezia A., Vermi A. C., Villari B., Zampi G., Zannoni J., Zito C., Zugaro A., Di Bella G., Carerj S., Ciampi, Q, Pepi, M, Antonini-Canterin, F, Barbieri, A, Barchitta, A, Faganello, G, Miceli, S, Parato, V, Tota, A, Trocino, G, Abbate, M, Accadia, M, Alemanni, R, Angelini, A, Anglano, F, Anselmi, M, Aquila, I, Aramu, S, Avogadri, E, Azzaro, G, Badano, L, Balducci, A, Ballocca, F, Barbarossa, A, Barbati, G, Barletta, V, Barone, D, Becherini, F, Benfari, G, Beraldi, M, Bergandi, G, Bilardo, G, Binno, S, Bolognesi, M, Bongiovi, S, Bragato, R, Braggion, G, Brancaleoni, R, Bursi, F, Dessalvi, C, Cameli, M, Canu, A, Capitelli, M, Capra, A, Carbonara, R, Carbone, M, Carbonella, M, Carrabba, N, Casavecchia, G, Casula, M, Chesi, E, Cicco, S, Citro, R, Cocchia, R, Colombo, B, Colonna, P, Conte, M, Corrado, G, Cortesi, P, Cortigiani, L, Costantino, M, Cozza, F, Cucchini, U, D'Angelo, M, Ros, S, D'Andrea, F, D'Andrea, A, D'Auria, F, De Caridi, G, De Feo, S, De Matteis, G, De Vecchi, S, Del Giudice, C, Dell'Angela, L, Delli Paoli, L, Dentamaro, I, Destefanis, P, Di Fulvio, M, Di Gaetano, R, Di Giannuario, G, Di Gioia, A, Di Martino, L, Di Muro, C, Di Nora, C, Di Salvo, G, Dodi, C, Dogliani, S, Donati, F, Dottori, M, Epifani, G, Fabiani, I, Ferrara, F, Ferrara, L, Ferrua, S, Filice, G, Fiorino, M, Forno, D, Garini, A, Giarratana, G, Gigantino, G, Giorgi, M, Giubertoni, E, Greco, C, Grigolato, M, Marra, W, Holzl, A, Iaiza, A, Iannaccone, A, Ilardi, F, Imbalzano, E, Inciardi, R, Inserra, C, Iori, E, Izzo, A, La Rosa, G, Labanti, G, Lanzone, A, Lanzoni, L, Lapetina, O, Leiballi, E, Librera, M, Lo Conte, C, Lo Monaco, M, Lombardo, A, Luciani, M, Lusardi, P, Magnante, A, Malagoli, A, Malatesta, G, Mancusi, C, Manes, M, Manganelli, F, Mantovani, F, Manuppelli, V, Marchese, V, Marinacci, L, Mattioli, R, Maurizio, C, Mazza, G, Mazza, S, Melis, M, Meloni, G, Merli, E, Milan, A, Minardi, G, Monaco, A, Monte, I, Montresor, G, Moreo, A, Mori, F, Morini, S, Moro, C, Morrone, D, Negri, F, Nipote, C, Nisi, F, Nocco, S, Novello, L, Nunziata, L, Perini, A, Parodi, A, Pasanisi, E, Pastorini, G, Pavasini, R, Pavoni, D, Pedone, C, Pelliccia, F, Pelliciari, G, Pelloni, E, Pergola, V, Perillo, G, Petruccelli, E, Pezzullo, C, Piacentini, G, Picardi, E, Pinna, G, Pizzarelli, M, Pizzuti, A, Poggi, M, Posteraro, A, Privitera, C, Rampazzo, D, Ratti, C, Rettegno, S, Ricci, F, Ricci, C, Rolando, C, Rossi, S, Rovera, C, Ruggieri, R, Russo, M, Sacchi, N, Saladino, A, Sani, F, Sartori, C, Scarabeo, V, Sciacqua, A, Scillone, A, Scopelliti, P, Scorza, A, Scozzafava, A, Serafini, F, Serra, W, Severino, S, Simeone, B, Sirico, D, Solari, M, Spadaro, G, Stefani, L, Strangio, A, Surace, F, Tamborini, G, Tarquinio, N, Tassone, E, Tavarozzi, I, Tchana, B, Tedesco, G, Tinto, M, Torzillo, D, Totaro, A, Triolo, O, Troisi, F, Tusa, M, Vancheri, F, Varasano, V, Venezia, A, Vermi, A, Villari, B, Zampi, G, Zannoni, J, Zito, C, Zugaro, A, Di Bella, G, Carerj, S, Ciampi Q., Pepi M., Antonini-Canterin F., Barbieri A., Barchitta A., Faganello G., Miceli S., Parato V. M., Tota A., Trocino G., Abbate M., Accadia M., Alemanni R., Angelini A., Anglano F., Anselmi M., Aquila I., Aramu S., Avogadri E., Azzaro G., Badano L., Balducci A., Ballocca F., Barbarossa A., Barbati G., Barletta V., Barone D., Becherini F., Benfari G., Beraldi M., Bergandi G., Bilardo G., Binno S. M., Bolognesi M., Bongiovi S., Bragato R. M., Braggion G., Brancaleoni R., Bursi F., Dessalvi C. C., Cameli M., Canu A., Capitelli M., Capra A. C. M., Carbonara R., Carbone M., Carbonella M., Carrabba N., Casavecchia G., Casula M., Chesi E., Cicco S., Citro R., Cocchia R., Colombo B. M., Colonna P., Conte M., Corrado G., Cortesi P., Cortigiani L., Costantino M. F., Cozza F., Cucchini U., D'Angelo M., Ros S. D., D'Andrea F., D'Andrea A., D'Auria F., De Caridi G., De Feo S., De Matteis G. M., De Vecchi S., Del Giudice C., Dell'Angela L., Delli Paoli L., Dentamaro I., Destefanis P., Di Fulvio M., Di Gaetano R., Di Giannuario G., Di Gioia A., Di Martino L. F. M., Di Muro C., Di Nora C., Di Salvo G., Dodi C., Dogliani S., Donati F., Dottori M., Epifani G., Fabiani I., Ferrara F., Ferrara L., Ferrua S., Filice G., Fiorino M., Forno D., Garini A., Giarratana G. A., Gigantino G., Giorgi M., Giubertoni E., Greco C. A., Grigolato M., Marra W. G., Holzl A., Iaiza A., Iannaccone A., Ilardi F., Imbalzano E., Inciardi R., Inserra C. A., Iori E., Izzo A., La Rosa G., Labanti G., Lanzone A. M., Lanzoni L., Lapetina O., Leiballi E., Librera M., Lo Conte C., Lo Monaco M., Lombardo A., Luciani M., Lusardi P., Magnante A., Malagoli A., Malatesta G., Mancusi C., Manes M. T., Manganelli F., Mantovani F., Manuppelli V., Marchese V., Marinacci L., Mattioli R., Maurizio C., Mazza G. A., Mazza S., Melis M., Meloni G., Merli E., Milan A., Minardi G., Monaco A., Monte I., Montresor G., Moreo A., Mori F., Morini S., Moro C., Morrone D., Negri F., Nipote C., Nisi F., Nocco S., Novello L., Nunziata L., Perini A. P., Parodi A., Pasanisi E. M., Pastorini G., Pavasini R., Pavoni D., Pedone C., Pelliccia F., Pelliciari G., Pelloni E., Pergola V., Perillo G., Petruccelli E., Pezzullo C., Piacentini G., Picardi E., Pinna G., Pizzarelli M., Pizzuti A., Poggi M. M., Posteraro A., Privitera C., Rampazzo D., Ratti C., Rettegno S., Ricci F., Ricci C., Rolando C., Rossi S., Rovera C., Ruggieri R., Russo M. G., Sacchi N., Saladino A., Sani F., Sartori C., Scarabeo V., Sciacqua A., Scillone A., Scopelliti P. A., Scorza A., Scozzafava A., Serafini F., Serra W., Severino S., Simeone B., Sirico D., Solari M., Spadaro G. L., Stefani L., Strangio A., Surace F. C., Tamborini G., Tarquinio N., Tassone E. J., Tavarozzi I., Tchana B., Tedesco G., Tinto M., Torzillo D., Totaro A., Triolo O. F., Troisi F., Tusa M., Vancheri F., Varasano V., Venezia A., Vermi A. C., Villari B., Zampi G., Zannoni J., Zito C., Zugaro A., Di Bella G., and Carerj S.

Abstract

Background: The Italian Society of Echocardiography and Cardiovascular Imaging (SIECVI) conducted a national survey to understand better how different echocardiographic modalities are used and accessed in Italy. Methods: We analyzed echocardiography laboratory activities over a month (November 2022). Data were retrieved via an electronic survey based on a structured questionnaire, uploaded on the SIECVI website. Results: Data were obtained from 228 echocardiographic laboratories: 112 centers (49%) in the northern, 43 centers (19%) in the central, and 73 (32%) in the southern regions. During the month of observation, we collected 101,050 transthoracic echocardiography (TTE) examinations performed in all centers. As concern other modalities there were performed 5497 transesophageal echocardiography (TEE) examinations in 161/228 centers (71%); 4057 stress echocardiography (SE) examinations in 179/228 centers (79%); and examinations with ultrasound contrast agents (UCAs) in 151/228 centers (66%). We did not find significant regional variations between the different modalities. The usage of picture archiving and communication system (PACS) was significantly higher in the northern (84%) versus central (49%) and southern (45%) centers (P < 0.001). Lung ultrasound (LUS) was performed in 154 centers (66%), without difference between cardiology and noncardiology centers. The evaluation of left ventricular (LV) ejection fraction was evaluated mainly using the qualitative method in 223 centers (94%), occasionally with the Simpson method in 193 centers (85%), and with selective use of the three-dimensional (3D) method in only 23 centers (10%). 3D TTE was present in 137 centers (70%), and 3D TEE in all centers where TEE was done (71%). The assessment of LV diastolic function was done routinely in 80% of the centers. Right ventricular function was evaluated using tricuspid annular plane systolic excursion in all centers, using tricuspid valve annular systolic velocity by tissue

Published
2023

10. Intervendor Consistency and Accuracy of Left Ventricular Volume Measurements Using Three-Dimensional Echocardiography

Author

Muraru, D, Cecchetto, A, Cucchini, U, Zhou, X, Lang, R, Romeo, G, Vannan, M, Mihaila, S, Miglioranza, M, Iliceto, S, Badano, L, Muraru D., Cecchetto A., Cucchini U., Zhou X., Lang R. M., Romeo Gabriella, Vannan M., Mihaila S., Miglioranza M. H., Iliceto S., Badano L., Muraru, D, Cecchetto, A, Cucchini, U, Zhou, X, Lang, R, Romeo, G, Vannan, M, Mihaila, S, Miglioranza, M, Iliceto, S, Badano, L, Muraru D., Cecchetto A., Cucchini U., Zhou X., Lang R. M., Romeo Gabriella, Vannan M., Mihaila S., Miglioranza M. H., Iliceto S., and Badano L.

Abstract

Background: Intervendor consistency of left ventricular (LV) volume measurements using three-dimensional transthoracic echocardiography (3DTTE) has never been reported. Accordingly, we designed a prospective study to (1) compare head-to-head the accuracy of three three-dimensional echocardiography (3DE) systems in measuring LV volumes and ejection fraction (EF) against cardiac magnetic resonance (CMR); (2) assess the intervendor variability of LV volumes and EF; and (3) compare the accuracy of fully automated versus semiautomated (i.e., manually corrected) methods of LV endocardial delineation against CMR.Methods: We studied 92 patients (64% males, 52 years [95% CI, 20-83]) with a wide range of end-diastolic volumes (from 87 to 446 mL) and EFs (from 16% to 77%) using three different 3DE platforms (iE33; VividE9; Acuson SC2000) during the same echo study. CMR was performed within 3 6 5 hours from the 3DE study in 35 patients.Results: LV volumes provided by the three 3DE systems correlated with CMR volumes: end-diastolic volume (iE33: R-2 = 0.93; E9: R-2 = 0.94; SC2000: R-2 = 0.94), end-systolic volume (iE33: R-2 = 0.93; E9: R-2 = 0.95; SC2000: R-2 = 0.94), and EF (iE33: R-2 = 0.79; E9: R-2 = 0.80; SC2000: R-2 = 0.77). In the 92 patients studied, LV volumes and EFs measured with the three systems were similar. Use of fully automated endocardial border detection algorithms significantly underestimated LV volumes, and the degree of underestimation was higher with larger LV volumes.Conclusions: LV volumes and EFs measured with the three 3DE systems are consistent. Fully automated algorithms underestimated LV volumes. Our findings may help in the clinical interpretation of LV parameters obtained using different 3DE systems and encourage the clinical use of 3DTTE.

Published
2018

24. Sex- and method-specific reference values for right ventricular strain by 2-dimensional speckle-tracking echocardiography

Author

Muraru, D, Onciul, S, Peluso, D, Soriani, N, Cucchini, U, Aruta, P, Romeo, G, Cavalli, G, Iliceto, S, Badano, L, Muraru D., Onciul S., Peluso D., Soriani N., Cucchini U., Aruta P., Romeo G., Cavalli G., Iliceto S., Badano L., Muraru, D, Onciul, S, Peluso, D, Soriani, N, Cucchini, U, Aruta, P, Romeo, G, Cavalli, G, Iliceto, S, Badano, L, Muraru D., Onciul S., Peluso D., Soriani N., Cucchini U., Aruta P., Romeo G., Cavalli G., Iliceto S., and Badano L.

Abstract

Background - Despite the fact that assessment of right ventricular longitudinal strain (RVLS) carries important implications for patient diagnosis, prognosis, and treatment, its implementation in clinical settings has been hampered by the limited reference values and the lack of uniformity in software, method, and definition used for measuring RVLS. Accordingly, this study was designed to establish (1) the reference values for RVLS by 2-dimensional speckle-tracking echocardiography; and (2) their relationship with demographic, hemodynamic, and cardiac factors. Methods and Results - In 276 healthy volunteers (55% women; age, 18-76 years), free wall and septum RVLS (6 segments) and free wall RVLS (3 segments) using both 6- and 3-segment regions of interest were obtained. Feasibility of 6-segment RVLS was 92%. Free wall RVLS from 3- versus 6-segment regions of interest had similar values, yet 6-segment region of interest was more feasible (86% versus 73%; P<0.001) and reproducible. Reference values (lower limits of normality) were as follows: 6-segment RVLS, -24.7±2.6% (-20.0%) for men and -26.7±3.1% (-20.3%) for women; 3-segment RVLS, -29.3±3.4% (-22.5%) for men and -31.6±4.0% (-23.3%) for women (P<0.001). Free wall RVLS was 5±2 strain units (%) larger in magnitude than 6-segment RVLS, 10±4% larger than septal RVLS, and 2±4% larger in women than in men (P<0.001). At multivariable analysis, age, sex, pulmonary systolic pressure, right atrial minimal volume, as well as right atrial and left ventricular longitudinal strain resulted as correlates of RVLS values. Conclusions - This is the largest study providing sex- and method-specific reference values for RVLS. Our data may foster the implementation of 2-dimensional speckle-tracking echocardiography-derived RV analysis in clinical practice.

Published
2016

25. Left atrial volumes and function by three-dimensional echocardiography: Reference values, accuracy, reproducibility, and comparison with two-dimensional echocardiographic measurements

Author

Badano, L, Miglioranza, M, Mihaila, S, Peluso, D, Xhaxho, J, Marra, M, Cucchini, U, Soriani, N, Iliceto, S, Muraru, D, Badano L., Miglioranza M. H., MihAilA S., Peluso D., Xhaxho J., Marra M. P., Cucchini U., Soriani N., Iliceto S., Muraru D., Badano, L, Miglioranza, M, Mihaila, S, Peluso, D, Xhaxho, J, Marra, M, Cucchini, U, Soriani, N, Iliceto, S, Muraru, D, Badano L., Miglioranza M. H., MihAilA S., Peluso D., Xhaxho J., Marra M. P., Cucchini U., Soriani N., Iliceto S., and Muraru D.

Abstract

Background - Our study sought to (1) identify reference values for left atrial (LA) volumes and phasic function indices by 3-dimensional echocardiography (3DE) and compare them with those measured by 2-dimensional echocardiography (2DE) and (2) analyze their relationship with age, sex, body size, and left ventricular function. Accuracy and reproducibility of 3DE and 2DE have been also tested to evaluate the robustness of our data. Methods and Results - We obtained maximal, minimal, and preA LA volumes by 3DE and 2DE in 276 healthy volunteers (18-79 years; 57% women). Limits of normality for LA volumes and total LA emptying fraction were larger with 3DE than with 2DE (maximal LA volume: 43 versus 35 mL/m2; preA LA volume: 31 versus 25 mL/m2; minimal LA volume: 18 versus 14 mL/m2; 53 versus 48%, respectively; P<0.001). 3DE LA volumes indexed by body surface area were similar in men and women and increased with age. On multivariable analysis, age, weight, and left ventricular systolic and diastolic function indices resulted as correlates of LA 3DE indices. LA volumes were tightly correlated with cardiac magnetic resonance measurements, yet more underestimated by 2DE versus 3DE (bias±SD: -17±16 versus -7±15 mL, respectively). Among all LA parameters, maximal LA volume and total emptying fraction were the most reproducible, including at test-retest and at expert versus trainee comparisons. Conclusions - This study provides reference values for LA 3DE volumes and function from a relatively large cohort of healthy subjects with a wide age range. Our data may help clinicians to identify LA remodeling and dysfunction.

Published
2016

26. Physiologic Determinants of Left Atrial Longitudinal Strain: A Two-Dimensional Speckle-Tracking and Three-Dimensional Echocardiographic Study in Healthy Volunteers

Author

Miglioranza, M, Badano, L, Mihaila, S, Peluso, D, Cucchini, U, Soriani, N, Iliceto, S, Muraru, D, Miglioranza M. H., Badano L., Mihaila S., Peluso D., Cucchini U., Soriani N., Iliceto S., Muraru D., Miglioranza, M, Badano, L, Mihaila, S, Peluso, D, Cucchini, U, Soriani, N, Iliceto, S, Muraru, D, Miglioranza M. H., Badano L., Mihaila S., Peluso D., Cucchini U., Soriani N., Iliceto S., and Muraru D.

Abstract

Background Left atrial (LA) longitudinal strain (LS) using two-dimensional speckle-tracking echocardiography has emerged as an important diagnostic and prognostic parameter in various cardiovascular conditions. However, its reference values, their correlations with demographics characteristics, and its physiologic determinants remain to be established. Methods Accordingly, 171 healthy volunteers (mean age, 45 ± 12 years; 61% women) in whom LS was obtained from both apical four- and two-chamber dedicated views of the left atrium, considering the P-P interval on the electrocardiogram as the reference cardiac cycle, were prospectively studied. From the LA LS curve we measured the extent of the negative deflection (LSneg), representing LA active contraction, the positive deflection (LSpos) during LA filling, and total LS (LStot), as the sum of LSneg and LSpos values. Results Average values for biplane LA LSpos, LSneg, and LStot were 19.7%, −14.5%, and 33.3%, respectively. On multivariate analysis, age, left ventricular (LV) global LS and volume, and LV diastolic function were the main physiologic determinants of LA LSpos (R2 = 0.57) and LStot (R2 = 0.40), whereas systolic blood pressure, E/A ratio, global LS, and LV stroke volume were the main determinants of LA LSneg (R2 = 0.20). Women had higher LSpos and LStot than men, particularly before 50 years of age. LA LSpos and LStot decreased with aging, with different trends in men and women. Conclusions LA LS values are different in men and women and should be interpreted taking into account patient age and LV function as well. These reference values may help identify subclinical LA dysfunction in several cardiovascular or systemic conditions.

Published
2016

27. New speckle-tracking algorithm for right ventricular volume analysis from three-dimensional echocardiographic data sets: validation with cardiac magnetic resonance and comparison with the previous analysis tool

Author

Muraru, D, Spadotto, V, Cecchetto, A, Romeo, G, Aruta, P, Ermacora, D, Jenei, C, Cucchini, U, Iliceto, S, Badano, L, Muraru D., Spadotto V., Cecchetto A., Romeo G., Aruta P., Ermacora D., Jenei C., Cucchini U., Iliceto S., Badano L., Muraru, D, Spadotto, V, Cecchetto, A, Romeo, G, Aruta, P, Ermacora, D, Jenei, C, Cucchini, U, Iliceto, S, Badano, L, Muraru D., Spadotto V., Cecchetto A., Romeo G., Aruta P., Ermacora D., Jenei C., Cucchini U., Iliceto S., and Badano L.

Abstract

AIMS: (i) To validate a new software for right ventricular (RV) analysis by 3D echocardiography (3DE) against cardiac magnetic resonance (CMR); (ii) to assess the accuracy of different measurement approaches; and (iii) to explore any benefits vs. the previous software.METHODS AND RESULTS: We prospectively studied with 3DE and CMR 47 patients (14-82 years, 28 men) having a wide range of RV end-diastolic volumes (EDV 82-354 mL at CMR) and ejection fractions (EF 34-81%). Multi-beat RV 3DE data sets were independently analysed with the new software using both automated and manual editing options, as well as with the previous software. RV volume reproducibility was tested in 15 random patients. RV volumes and EF measurements by the new software had an excellent accuracy (bias ± SD: -15 ± 24 mL for EDV; 1.4 ± 4.9% for EF) and reproducibility compared with CMR, provided that the RV borders automatically tracked by software were systematically edited by operator. The automated analysis option underestimated the EDV, overestimated the ESV, and largely underestimated the EF (bias ± SD: -17 ± 10%). RV volumes measured with the new software using manual editing showed similar accuracy, but lower inter-observer variability and shorter analysis time (3-5') in comparison with the previous software.CONCLUSION: Novel vendor-independent 3DE software enables an accurate, reproducible and faster quantitation of RV volumes and ejection fraction. Rather than optional, systematic verification of border tracking quality and manual editing are mandatory to ensure accurate 3DE measurements. These findings are relevant for echocardiography laboratories aiming to implement 3DE for RV analysis for both research and clinical purposes.

Published
2016

30. Cardioembolic Stroke in Patient with Transcatheter Occluded Left Atrial Appendage

Author

Cucchini, U, Muraru, D, Badano, L, Cucchini, U, Muraru, D, and Badano, L

Abstract

A cerebral ischemic event in a patient managed with left atrial appendage (LAA) transcatheter obliteration is illustrated. Transesophageal echocardiography allowed identification and accurate definition of the LAA device leakage.

Published
2018

31. Sunday, 30 August 2015

Author

Cecchetto, A, Muraru, D, Ermacora, D, Romeo, G, Maddalozzo, A, Onciu, S, Cucchini, U, Iliceto, S, Badano, L, Cecchetto A, Muraru D, Ermacora D, Romeo G, Maddalozzo A, Onciu S, Cucchini U, Iliceto S, Badano L, Cecchetto, A, Muraru, D, Ermacora, D, Romeo, G, Maddalozzo, A, Onciu, S, Cucchini, U, Iliceto, S, Badano, L, Cecchetto A, Muraru D, Ermacora D, Romeo G, Maddalozzo A, Onciu S, Cucchini U, Iliceto S, and Badano L

Published
2015

32. Impact of vendor-independent versus vendor-specific software packages on left ventricular volume measurements performed on 3D echo data sets obtained from different echo systems

Author

Cecchetto, A, Muraru, D, Ermacora, D, Romeo, G, Maddalozzo, A, Onciul, S, Cucchini, U, Iliceto, S, Badano, L, Cecchetto Antonella, Muraru Denisa, Ermacora Davie, Romeo Gabriella, Maddalozzo Anna, Onciul S, Cucchini U, Iliceto S, Badano Luigi, Cecchetto, A, Muraru, D, Ermacora, D, Romeo, G, Maddalozzo, A, Onciul, S, Cucchini, U, Iliceto, S, Badano, L, Cecchetto Antonella, Muraru Denisa, Ermacora Davie, Romeo Gabriella, Maddalozzo Anna, Onciul S, Cucchini U, Iliceto S, and Badano Luigi

Published
2015

33. Low-Intensity Oral Anticoagulant Plus Low-Dose Aspirin During the First Six Months Versus Standard-Intensity Oral Anticoagulant Therapy After Mechanical Heart Valve Replacement: A Pilot Study of Low-Intensity Warfarin and Aspirin in Cardiac Prostheses (LIWACAP)

Author

Pengo V., Cucchini U., Molinatti M., Del Bono R., Baudo F., Ghirarduzzi A., Pegoraro C., Iliceto S., participating centers of Italian Federation of Anticoagulation Clinics, PALARETI, GUALTIERO, Pengo V., Palareti G., Cucchini U., Molinatti M., Del Bono R., Baudo F., Ghirarduzzi A., Pegoraro C., Iliceto S., and participating centers of Italian Federation of Anticoagulation Clinics (FCSA)

Subjects
Male, Aortic valve, medicine.medical_specialty, medicine.medical_treatment, Hemorrhage, Pilot Projects, Postoperative Hemorrhage, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Cumulative incidence, International Normalized Ratio, Postoperative Period, Prospective Studies, Heart valve, Stroke, Aged, Heart Valve Prosthesis Implantation, Aspirin, business.industry, Mitral valve replacement, Warfarin, Anticoagulants, Hematology, General Medicine, Middle Aged, medicine.disease, Thrombosis, Surgery, medicine.anatomical_structure, 030228 respiratory system, Aortic Valve, Anesthesia, Mitral Valve, Female, business, medicine.drug
Abstract

The objective of this study was to evaluate the safety and efficacy of low-intensity warfarin treatment plus aspirin during the first 6 months after surgery in patients undergoing heart valve substitution with mechanical prostheses. Vitamin K antagonists (VKA) are able to reduce but not eliminate thrombosis and systemic embolism in patients with mechanical heart valves. The intensity of treatment and additional use of aspirin in these patients is still controversial. Consecutive patients undergoing aortic or mitral valve replacement (or a combination of the two) with mechanical prostheses were invited to participate in the study. After stratifying for site of prosthesis, patients were randomized to receive low intensity VKA treatment (target INR 2.5) plus aspirin (100 mg/day) for the first six months (Group A) or standard-intensity (INR target 3.7) VKA treatment (Group B). Mean follow-up was 1.5 years. Principal outcome events were systemic embolism, major bleeding, and vascular death. A total of 94 patients in Group A and 104 in Group B were randomized and followed up for 144 and 163 patient years, respectively. There were 5 (5%) events in Group A (4 major bleeding events and 1 vascular death) and 4 (4%) in group B (2 major bleeding events and 2 ischemic stroke). All the events except 1 occurred within the first 6 months after surgery. Cumulative incidence of primary outcome events was 5.8% (95% CI 0.9 to 10.7) in Group A and 4.3% (95% CI 0,2 to 8.4) in Group B (p=0.6). Low-intensity treatment plus aspirin during the first six months after surgery appears to be as effective and safe as moderate-high-intensity anticoagulation.

Published
2007
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37. P4465Coronary angiography and revascularization in patients with peripheral artery disease undergoing percutaneous transluminal angioplasty

Author

Chirillo, F, primary, Cucchini, U, additional, Covolo, E, additional, Carasi, M, additional, Zadro, M, additional, Iavernaro, A, additional, Zasso, A, additional, Baritussio, A, additional, Bontorin, M, additional, Libardoni, M, additional, Galzignan, E, additional, Molon, E, additional, and Cognolato, D, additional

Published
2018
Full Text
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38. Right ventricular geometry and function in pulmonary hypertension: non-invasive evaluation

Author

Peluso, D, Tona, F, Muraru, D, Romeo, G, Cucchini, U, Marra, M, Iliceto, S, Badano, L, PELUSO D, TONA F, MURARU D, ROMEO G, CUCCHINI U, MARRA MP, ILICETO S, BADANO L, Peluso, D, Tona, F, Muraru, D, Romeo, G, Cucchini, U, Marra, M, Iliceto, S, Badano, L, PELUSO D, TONA F, MURARU D, ROMEO G, CUCCHINI U, MARRA MP, ILICETO S, and BADANO L

Abstract

Pulmonary hypertension (PH) is a rare disease, which still carries a poor prognosis. PH is characterized by a pressure overload on the right ventricle (RV), which develops hypertrophy, followed by a progressive failure. Accordingly, recent evidence showed that RV function has an important prognostic role in patients with PH. Echocardiography, cardiac magnetic resonance (CMR), computed tomography, and nuclear imaging allow a non-invasive evaluation of the RV size and function, but only the first two are routinely used in the clinical arena. Some conventional echocardiographic parameters, such as TAPSE (tricuspid anular plane systolic excursion), have demonstrated prognostic value in patients with PH. Moreover, there are some new advanced echo techniques, which can provide a more detailed assessment of RV function. Three-dimensional (3D) echocardiography allows measurement of RV volumes and ejection fraction, and two-dimensional (2D) speckle tracking (STE), allows assessment of RV myocardial mechanics. CMR provides accurate measurement of RV volumes, ejection fraction, and mass and allows the characterization of the RV wall composition by identifying the presence of fibrosis by late gadolinium enhancement. Although CMR seems to hold promise for both initial assessment and follow-up of patients with PH, its main role has been restricted to diagnostic work-up only

Published
2014

39. Poster session 4: Friday 5 December 2014, 08:30-12:30Location: Poster area

Author

Orii M, Tanimoto T, Yokoyama M, Ota S, Kubo T, Hirata K, Tanaka A, Imanishi T, Akasaka T, Michelsen M, Pena A, Mygind N, Hoest N, Prescott E, Abd El Dayem S, Battah A, Abd El Azzez F, Ahmed A, Fattoh A, Ismail R, Andjelkovic K, Kalimanovska Ostric D, Nedeljkovic I, Andjelkovic I, Rashid H, Abuel Enien H, Ibraheem M, Vago H, Toth A, Csecs I, Czimbalmos C, Suhai FI, Kecskes K, Becker D, Simor T, Merkely B, D'ascenzi F, Pelliccia A, Natali B, Cameli M, Lisi M, Focardi M, Corrado D, Bonifazi M, Mondillo S, Zaha V, Kim G, Su K, Zhang J, Mikush N, Ross J, Palmeri M, Young L, Tadic M, Ilic S, Celic V, Jaimes C, Gonzalez Mirelis J, Gallego M, Goirigolzarri J, Pellegrinet M, Poli S, Prati G, Vriz O, Di Bello V, Carerj S, Zito C, Mateescu A, Popescu B, Antonini Canterin F, Chatzistamatiou E, Moustakas G, Memo G, Konstantinidis D, Mpampatzeva Vagena I, Manakos K, Traxanas K, Vergi N, Feretou A, Kallikazaros I, Hewing B, Theres L, Dreger H, Spethmann S, Stangl K, Baumann G, Knebel F, Uejima T, Itatani K, Nakatani S, Lancellotti P, Seo Y, Zamorano J, Ohte N, Takenaka K, Naar J, Mortensen L, Johnson J, Winter R, Shahgaldi K, Manouras A, Braunschweig F, Stahlberg M, Coisne D, Al Arnaout AM, Tchepkou C, Raud Raynier P, Diakov C, Degand B, Christiaens L, Barbier P, Mirea O, Cefalu C, Savioli G, Guglielmo M, Maltagliati A, O'neill L, Walsh K, Hogan J, Manzoor T, Ahern B, Owens P, Sengelov M, Biering Sorensen T, Jorgensen P, Bruun N, Fritz Hansen T, Bech J, Olsen F, Sivertsen J, Jensen J, Marta L, Abecasis J, Reis C, Ribeiras R, Andrade M, Mendes M, D'andrea A, Stanziola A, Di Palma E, Martino M, Lanza M, Betancourt V, Maglione M, Calabro' R, Russo M, Bossone E, Vogt MO, Meierhofer Ch, Rutz T, Fratz S, Ewert P, Roehlig Ch, Kuehn A, Storsten P, Eriksen M, Remme E, Boe E, Smiseth O, Skulstad H, Ereminiene E, Ordiene R, Ivanauskas V, Vaskelyte J, Stoskute N, Kazakauskaite E, Benetis R, Marketou M, Parthenakis F, Kontaraki J, Zacharis E, Maragkoudakis S, Logakis J, Roufas K, Vougia D, Vardas P, Dado E, Knuti G, Djamandi J, Shota E, Sharka I, Saka J, Halmai L, Nemes A, Kardos A, Neubauer S, Kurnicka K, Domienik Karlowicz J, Lichodziejewska B, Goliszek S, Grudzka K, Krupa M, Dzikowska Diduch O, Ciurzynski M, Pruszczyk P, Chung H, Kim J, Yoon Y, Min P, Lee B, Hong B, Rim S, Kwon H, Choi E, Soya O, Kuryata O, Kakihara R, Naruse C, Inayoshi A, El Sebaie M, Frer A, Abdelsamie M, Eldamanhory A, Ciampi Q, Cortigiani L, Simioniuc A, Manicardi C, Villari B, Picano E, Sicari R, Ferferieva V, Deluyker D, Lambrichts I, Rigo J, Bito V, Kuznetsov V, Yaroslavskaya E, Krinochkin D, Pushkarev G, Gorbatenko E, Trzcinski P, Michalski B, Lipiec P, Szymczyk E, Peczek L, Nawrot B, Chrzanowski L, Kasprzak J, Todaro M, Khandheria B, Cusma Piccione M, La Carrubba S, Oreto G, Di Bella G, Gunyeli E, Oliveira Da Silva C, Sahlen A, Spampinato R, Tasca M, Roche E. Silva J, Strotdrees E, Schloma V, Dmitrieva Y, Dobrovie M, Borger M, Mohr F, Einarsen E, Cramariuc D, Lonnebakken M, Boman K, Gohlke Barwolf C, Chambers J, Gerdts E, Calin A, Rosca M, Beladan C, Mirescu Craciun A, Gurzun M, Enache R, Ginghina C, Antova E, Georgievska Ismail Lj, Srbinovska E, Andova V, Peovska I, Davceva J, Otljanska M, Vavulkis M, Tsuruta H, Kohsaka S, Murata M, Yasuda R, Dan M, Yashima F, Inohara T, Maekawa Y, Hayashida K, Fukuda K, Migliore R, Adaniya M, Barranco M, Miramont G, Gonzalez S, Tamagusuku H, Abid L, Ben Kahla S, Charfeddine S, Abid D, Kammoun S, Amano M, Izumi C, Miyake M, Tamura T, Kondo H, Kaitani K, Nakagawa Y, Ghulam Ali S, Fusini L, Tamborini G, Muratori M, Gripari P, Bottari V, Celeste F, Cefalu' C, Alamanni F, Pepi M, Obase K, Mor Avi V, Weinert L, Lang R, Teixeira R, Monteiro R, Garcia J, Ribeiro M, Cardim N, Goncalves L, Miglioranza M, Muraru D, Cavalli G, Addetia K, Cucchini U, Mihaila S, Veronesi F, Badano L, Galian Gay L, Gonzalez Alujas M, Teixido Tura G, Gutierrez Garcia L, Rodriguez Palomares J, Evangelista Masip A, Conte L, Fabiani I, Giannini C, La Carruba S, De Carlo M, Barletta V, Petronio A, Mahmoud H, Al Ghamdi M, Ghabashi A, Salaun E, Zenses A, Evin M, Collart F, Pibarot P, Habib G, Rieu R, Fabregat Andres O, Estornell Erill J, Cubillos Arango A, Bochard Villanueva B, Chacon Hernandez N, Higueras Ortega L, Perez Bosca L, Paya Serrano R, Ridocci Soriano F, Cortijo Gimeno J, Mzoughi K, Zairi I, Jabeur M, Ben Moussa F, Mrabet K, Kamoun S, Fennira S, Ben Chaabene A, Kraiem S, Schnell F, Betancur J, Daudin M, Simon A, Lentz P, Tavard F, Hernandes A, Carre F, Garreau M, Donal E, Abduch M, Vieira M, Antunes M, Mathias W, Mady C, Arteaga E, Alencar A, Tesic M, Djordjevic Dikic A, Beleslin B, Giga V, Trifunovic D, Petrovic O, Jovanovic I, Petrovic M, Stepanovic J, Vujisic Tesic B, Cha J, Kim Kh, Bergler Klein J, Geier C, Maurer G, Gyongyosi M, Cortes Garcia M, Oliva M, Navas M, Orejas M, Rabago R, Martinez M, Briongos S, Romero A, Rey M, Farre J, Ruisanchez Villar C, Ruiz Guerrero L, Rubio Ruiz S, Lerena Saenz P, Gonzalez Vilchez F, Hernandez Hernandez J, Armesto Alonso S, Blanco Alonso R, Martin Duran R, Gonzalez Gay M, Novo G, Marturana I, Bonomo V, Arvigo L, Evola V, Karfakis G, Lo Presti M, Verga S, Novo S, Petroni R, Acitelli A, Bencivenga S, Cicconetti M, Di Mauro M, Petroni A, Romano S, Penco M, Park S, Kim S, Kim M, Shim W, Majstorovic A, Ivanovic B, Driessen MM, Meijboom F, Mertens L, Dragulescu A, Friedberg M, De Stefano F, Santoro C, Buonauro A, Muscariello R, Lo Iudice F, Ierano P, Esposito R, Galderisi M, Sunbul M, Kivrak T, Durmus E, Yildizeli B, Mutlu B, Rodrigues A, Daminello E, Echenique L, Cordovil A, Oliveira W, Monaco Ch, Lira E, Fischer Ch, Morhy S, Mignot A, Jaussaud J, Chevalier L, Lafitte S, Curci V, Alvino F, Ikonomidis I, Pavlidis G, Lambadiari V, Kousathana F, Triantafyllidi H, Varoudi M, Dimitriadis G, Lekakis J, Cho JS, Cho E, Yoon H, Ihm Sh, Lee J, Molnar AA, Kovacs A, Apor A, Tarnoki A, Tarnoki D, Horvath T, Maurovich Horvat P, Jermendy G, Kiss R, Al Habbaa A, Petrovic Nagorni S, Ciric Zdravkovic S, Stanojevic D, Jankovic Tomasevic R, Atanaskovic V, Mitic V, Todorovic L, Dakic S, Park JS, Choi J, Kim Sh, Kwon Y, Jin H, Coppola C, Piscopo G, Galletta F, Maurea C, Esposito E, Barbieri A, Maurea N, Kaldararova M, Tittel P, Kantorova A, Vrsanska V, Kollarova E, Hraska V, Nosal M, Ondriska M, Masura J, Simkova I, Tadeu I, Azevedo O, Lourenco M, Luis F, Lourenco A, Planinc I, Bagadur G, Bijnens B, Ljubas J, Baricevic Z, Skoric B, Velagic V, Milicic D, Cikes M, Campanale CM, Di Maria S, Mega S, Nusca A, Marullo F, Di Sciascio G, El Tahlawi M, Abdallah M, Gouda M, Gad M, Elawady M, Igual Munoz B, Maceira Gonzalez Alicia A, Donate Betolin L, Vazquez Sanchez Alejandro A, Valera Martinez F, Sepulveda Sanchez P, Cervera Zamora A, Piquer Gil Marina M, Montero Argudo A, Naka K, Evangelou D, Lakkas L, Kalaitzidis R, Bechlioulis A, Gkirdis I, Tzeltzes G, Nakas G, Pappas K, Michalis L, Mansencal N, Bagate F, Arslan M, Siam Tsieu V, Deblaise J, El Mahmoud R, Dubourg O, Wierzbowska Drabik K, Plewka M, Bandera F, Generati G, Pellegrino M, Alfonzetti E, Labate V, Villani S, Gaeta M, Guazzi M, Grycewicz T, Szymanska K, Grabowicz W, Lubinski A, Sotaquira M, Caiani E, Garcia Gonzalez P, De La Espriella Juan R, Albiach Montanana C, Berenguer Jofresa A, Perez Bosca J, Cheng HL, Huang CH, Wang YC, Chou WH, Melnikov N, Kolunin G, Enina T, Sierraalta W, Le Bihan D, Barretto R, Assef J, Gospos M, Buffon M, Ramos A, Garcia A, Pinto I, Souza A, Mueller H, Reverdin S, Ehret G, Conti L, Dos Santos S, Abdel Moneim SS, Nhola LF, Huang R, Kohli M, Longenbach S, Green M, Villarraga HR, Bordun KA, Jassal DS, Mulvagh SL, Evangelista A, Madeo A, Piras P, Giordano F, Giura G, Teresi L, Gabriele S, Re F, Puddu P, Torromeo C, Suwannaphong S, Vathesatogkit P, See O, Yamwong S, Katekao W, Sritara P, Iliuta L, Szulik M, Streb W, Wozniak A, Lenarczyk R, Sliwinska A, Kalarus Z, Kukulski T, Weng KP, Lin CC, Hein S, Lehmann L, Kossack M, Juergensen L, Katus H, Hassel D, Turrini F, Scarlini S, Giovanardi P, Messora R, Mannucci C, Bondi M, Olander R, Sundholm J, Ojala T, Andersson S, Sarkola T, Karolyi M, Kocsmar I, Raaijmakers R, Kitslaar P, Szilveszter B, Tissue Doppler echocardiography research work, VFM international collaboration group, MTA SE Lendület Cardiovascular Imaging Research Group Heart, Vascular Center Semmelweis University Budapest Hungary, POLICINO, SALVATORE, Orii, M, Tanimoto, T, Yokoyama, M, Ota, S, Kubo, T, Hirata, K, Tanaka, A, Imanishi, T, Akasaka, T, Michelsen, M, Pena, A, Mygind, N, Hoest, N, Prescott, E, Abd El Dayem, S, Battah, A, Abd El Azzez, F, Ahmed, A, Fattoh, A, Ismail, R, Andjelkovic, K, Kalimanovska Ostric, D, Nedeljkovic, I, Andjelkovic, I, Rashid, H, Abuel Enien, H, Ibraheem, M, Vago, H, Toth, A, Csecs, I, Czimbalmos, C, Suhai, Fi, Kecskes, K, Becker, D, Simor, T, Merkely, B, D'Ascenzi, F, Pelliccia, A, Natali, B, Cameli, M, Lisi, M, Focardi, M, Corrado, D, Bonifazi, M, Mondillo, S, Zaha, V, Kim, G, Su, K, Zhang, J, Mikush, N, Ross, J, Palmeri, M, Young, L, Tadic, M, Ilic, S, Celic, V, Jaimes, C, Gonzalez Mirelis, J, Gallego, M, Goirigolzarri, J, Pellegrinet, M, Poli, S, Prati, G, Vriz, O, Di Bello, V, Carerj, S, Zito, C, Mateescu, A, Popescu, B, Antonini Canterin, F, Chatzistamatiou, E, Moustakas, G, Memo, G, Konstantinidis, D, Mpampatzeva Vagena, I, Manakos, K, Traxanas, K, Vergi, N, Feretou, A, Kallikazaros, I, Hewing, B, Theres, L, Dreger, H, Spethmann, S, Stangl, K, Baumann, G, Knebel, F, Uejima, T, Itatani, K, Nakatani, S, Lancellotti, P, Seo, Y, Zamorano, J, Ohte, N, Takenaka, K, Naar, J, Mortensen, L, Johnson, J, Winter, R, Shahgaldi, K, Manouras, A, Braunschweig, F, Stahlberg, M, Coisne, D, Al Arnaout, Am, Tchepkou, C, Raud Raynier, P, Diakov, C, Degand, B, Christiaens, L, Barbier, P, Mirea, O, Cefalu, C, Savioli, G, Guglielmo, M, Maltagliati, A, O'Neill, L, Walsh, K, Hogan, J, Manzoor, T, Ahern, B, Owens, P, Sengelov, M, Biering Sorensen, T, Jorgensen, P, Bruun, N, Fritz Hansen, T, Bech, J, Olsen, F, Sivertsen, J, Jensen, J, Marta, L, Abecasis, J, Reis, C, Ribeiras, R, Andrade, M, Mendes, M, D'Andrea, A, Stanziola, A, Di Palma, E, Martino, M, Lanza, M, Betancourt, V, Maglione, M, Calabro', R, Russo, M, Bossone, E, Vogt, Mo, Meierhofer, Ch, Rutz, T, Fratz, S, Ewert, P, Roehlig, Ch, Kuehn, A, Storsten, P, Eriksen, M, Remme, E, Boe, E, Smiseth, O, Skulstad, H, Ereminiene, E, Ordiene, R, Ivanauskas, V, Vaskelyte, J, Stoskute, N, Kazakauskaite, E, Benetis, R, Marketou, M, Parthenakis, F, Kontaraki, J, Zacharis, E, Maragkoudakis, S, Logakis, J, Roufas, K, Vougia, D, Vardas, P, Dado, E, Knuti, G, Djamandi, J, Shota, E, Sharka, I, Saka, J, Halmai, L, Nemes, A, Kardos, A, Neubauer, S, Kurnicka, K, Domienik Karlowicz, J, Lichodziejewska, B, Goliszek, S, Grudzka, K, Krupa, M, Dzikowska Diduch, O, Ciurzynski, M, Pruszczyk, P, Chung, H, Kim, J, Yoon, Y, Min, P, Lee, B, Hong, B, Rim, S, Kwon, H, Choi, E, Soya, O, Kuryata, O, Kakihara, R, Naruse, C, Inayoshi, A, El Sebaie, M, Frer, A, Abdelsamie, M, Eldamanhory, A, Ciampi, Q, Cortigiani, L, Simioniuc, A, Manicardi, C, Villari, B, Picano, E, Sicari, R, Ferferieva, V, Deluyker, D, Lambrichts, I, Rigo, J, Bito, V, Kuznetsov, V, Yaroslavskaya, E, Krinochkin, D, Pushkarev, G, Gorbatenko, E, Trzcinski, P, Michalski, B, Lipiec, P, Szymczyk, E, Peczek, L, Nawrot, B, Chrzanowski, L, Kasprzak, J, Todaro, M, Khandheria, B, Cusma Piccione, M, La Carrubba, S, Oreto, G, Di Bella, G, Gunyeli, E, Oliveira Da Silva, C, Sahlen, A, Spampinato, R, Tasca, M, Roche E., Silva J, Strotdrees, E, Schloma, V, Dmitrieva, Y, Dobrovie, M, Borger, M, Mohr, F, Einarsen, E, Cramariuc, D, Lonnebakken, M, Boman, K, Gohlke Barwolf, C, Chambers, J, Gerdts, E, Calin, A, Rosca, M, Beladan, C, Mirescu Craciun, A, Gurzun, M, Enache, R, Ginghina, C, Antova, E, Georgievska Ismail, Lj, Srbinovska, E, Andova, V, Peovska, I, Davceva, J, Otljanska, M, Vavulkis, M, Tsuruta, H, Kohsaka, S, Murata, M, Yasuda, R, Dan, M, Yashima, F, Inohara, T, Maekawa, Y, Hayashida, K, Fukuda, K, Migliore, R, Adaniya, M, Barranco, M, Miramont, G, Gonzalez, S, Tamagusuku, H, Abid, L, Ben Kahla, S, Charfeddine, S, Abid, D, Kammoun, S, Amano, M, Izumi, C, Miyake, M, Tamura, T, Kondo, H, Kaitani, K, Nakagawa, Y, Ghulam Ali, S, Fusini, L, Tamborini, G, Muratori, M, Gripari, P, Bottari, V, Celeste, F, Cefalu', C, Alamanni, F, Pepi, M, Obase, K, Mor Avi, V, Weinert, L, Lang, R, Teixeira, R, Monteiro, R, Garcia, J, Ribeiro, M, Cardim, N, Goncalves, L, Miglioranza, M, Muraru, D, Cavalli, G, Addetia, K, Cucchini, U, Mihaila, S, Veronesi, F, Badano, L, Galian Gay, L, Gonzalez Alujas, M, Teixido Tura, G, Gutierrez Garcia, L, Rodriguez Palomares, J, Evangelista Masip, A, Conte, L, Fabiani, I, Giannini, C, La Carruba, S, De Carlo, M, Barletta, V, Petronio, A, Mahmoud, H, Al Ghamdi, M, Ghabashi, A, Salaun, E, Zenses, A, Evin, M, Collart, F, Pibarot, P, Habib, G, Rieu, R, Fabregat Andres, O, Estornell Erill, J, Cubillos Arango, A, Bochard Villanueva, B, Chacon Hernandez, N, Higueras Ortega, L, Perez Bosca, L, Paya Serrano, R, Ridocci Soriano, F, Cortijo Gimeno, J, Mzoughi, K, Zairi, I, Jabeur, M, Ben Moussa, F, Mrabet, K, Kamoun, S, Fennira, S, Ben Chaabene, A, Kraiem, S, Schnell, F, Betancur, J, Daudin, M, Simon, A, Lentz, P, Tavard, F, Hernandes, A, Carre, F, Garreau, M, Donal, E, Abduch, M, Vieira, M, Antunes, M, Mathias, W, Mady, C, Arteaga, E, Alencar, A, Tesic, M, Djordjevic Dikic, A, Beleslin, B, Giga, V, Trifunovic, D, Petrovic, O, Jovanovic, I, Petrovic, M, Stepanovic, J, Vujisic Tesic, B, Cha, J, Kim, Kh, Bergler Klein, J, Geier, C, Maurer, G, Gyongyosi, M, Cortes Garcia, M, Oliva, M, Navas, M, Orejas, M, Rabago, R, Martinez, M, Briongos, S, Romero, A, Rey, M, Farre, J, Ruisanchez Villar, C, Ruiz Guerrero, L, Rubio Ruiz, S, Lerena Saenz, P, Gonzalez Vilchez, F, Hernandez Hernandez, J, Armesto Alonso, S, Blanco Alonso, R, Martin Duran, R, Gonzalez Gay, M, Novo, G, Marturana, I, Bonomo, V, Arvigo, L, Evola, V, Karfakis, G, Lo Presti, M, Verga, S, Novo, S, Petroni, R, Acitelli, A, Bencivenga, S, Cicconetti, M, Di Mauro, M, Petroni, A, Romano, S, Penco, M, Park, S, Kim, S, Kim, M, Shim, W, Majstorovic, A, Ivanovic, B, Driessen, Mm, Meijboom, F, Mertens, L, Dragulescu, A, Friedberg, M, De Stefano, F, Santoro, C, Buonauro, A, Muscariello, R, Lo Iudice, F, Ierano, P, Esposito, R, Galderisi, M, Sunbul, M, Kivrak, T, Durmus, E, Yildizeli, B, Mutlu, B, Rodrigues, A, Daminello, E, Echenique, L, Cordovil, A, Oliveira, W, Monaco, Ch, Lira, E, Fischer, Ch, Morhy, S, Mignot, A, Jaussaud, J, Chevalier, L, Lafitte, S, Curci, V, Alvino, F, Ikonomidis, I, Pavlidis, G, Lambadiari, V, Kousathana, F, Triantafyllidi, H, Varoudi, M, Dimitriadis, G, Lekakis, J, Cho, J, Cho, E, Yoon, H, Ihm, Sh, Lee, J, Molnar, Aa, Kovacs, A, Apor, A, Tarnoki, A, Tarnoki, D, Horvath, T, Maurovich Horvat, P, Jermendy, G, Kiss, R, Al Habbaa, A, Petrovic Nagorni, S, Ciric Zdravkovic, S, Stanojevic, D, Jankovic Tomasevic, R, Atanaskovic, V, Mitic, V, Todorovic, L, Dakic, S, Park, J, Choi, J, Kim, Sh, Kwon, Y, Jin, H, Coppola, C, Piscopo, G, Galletta, F, Maurea, C, Esposito, E, Barbieri, A, Maurea, N, Kaldararova, M, Tittel, P, Kantorova, A, Vrsanska, V, Kollarova, E, Hraska, V, Nosal, M, Ondriska, M, Masura, J, Simkova, I, Tadeu, I, Azevedo, O, Lourenco, M, Luis, F, Lourenco, A, Planinc, I, Bagadur, G, Bijnens, B, Ljubas, J, Baricevic, Z, Skoric, B, Velagic, V, Milicic, D, Cikes, M, Campanale, Cm, Di Maria, S, Mega, S, Nusca, A, Marullo, F, Di Sciascio, G, El Tahlawi, M, Abdallah, M, Gouda, M, Gad, M, Elawady, M, Igual Munoz, B, Maceira Gonzalez Alicia, A, Donate Betolin, L, Vazquez Sanchez Alejandro, A, Valera Martinez, F, Sepulveda Sanchez, P, Cervera Zamora, A, Piquer Gil Marina, M, Montero Argudo, A, Naka, K, Evangelou, D, Lakkas, L, Kalaitzidis, R, Bechlioulis, A, Gkirdis, I, Tzeltzes, G, Nakas, G, Pappas, K, Michalis, L, Mansencal, N, Bagate, F, Arslan, M, Siam Tsieu, V, Deblaise, J, El Mahmoud, R, Dubourg, O, Wierzbowska Drabik, K, Plewka, M, Bandera, F, Generati, G, Pellegrino, M, Alfonzetti, E, Labate, V, Villani, S, Gaeta, M, Guazzi, M, Grycewicz, T, Szymanska, K, Grabowicz, W, Lubinski, A, Sotaquira, M, Caiani, E, Garcia Gonzalez, P, De La Espriella Juan, R, Albiach Montanana, C, Berenguer Jofresa, A, Perez Bosca, J, Cheng, Hl, Huang, Ch, Wang, Yc, Chou, Wh, Melnikov, N, Kolunin, G, Enina, T, Sierraalta, W, Le Bihan, D, Barretto, R, Assef, J, Gospos, M, Buffon, M, Ramos, A, Garcia, A, Pinto, I, Souza, A, Mueller, H, Reverdin, S, Ehret, G, Conti, L, Dos Santos, S, Abdel Moneim, S, Nhola, Lf, Huang, R, Kohli, M, Longenbach, S, Green, M, Villarraga, Hr, Bordun, Ka, Jassal, D, Mulvagh, Sl, Evangelista, A, Madeo, A, Piras, P, Giordano, F, Giura, G, Teresi, L, Gabriele, S, Re, F, Puddu, P, Torromeo, C, Suwannaphong, S, Vathesatogkit, P, See, O, Yamwong, S, Katekao, W, Sritara, P, Iliuta, L, Szulik, M, Streb, W, Wozniak, A, Lenarczyk, R, Sliwinska, A, Kalarus, Z, Kukulski, T, Weng, Kp, Lin, Cc, Hein, S, Lehmann, L, Kossack, M, Juergensen, L, Katus, H, Hassel, D, Turrini, F, Scarlini, S, Giovanardi, P, Messora, R, Mannucci, C, Bondi, M, Olander, R, Sundholm, J, Ojala, T, Andersson, S, Sarkola, T, Karolyi, M, Kocsmar, I, Raaijmakers, R, Kitslaar, P, Szilveszter, B, Tissue Doppler echocardiography research, Work, VFM international collaboration, Group, MTA SE Lendület Cardiovascular Imaging Research Group, Heart, Vascular Center Semmelweis University Budapest, Hungary, and Policino, Salvatore

Subjects
Medical education, business.industry, Medicine, Radiology, Nuclear Medicine and imaging, Friday 5 December 2014, General Medicine, Session (computer science), Cardiology and Cardiovascular Medicine, business
Published
2014

40. P1438Free wall strain analysis allows identification of subclinical right ventricular dysfunction among patients with early cardiotoxicity

Author

Cherata, D.A., primary, Rodriguez-Zanella, H., additional, Muraru, D., additional, Palermo, C., additional, Cucchini, U., additional, Aruta, P., additional, Carstea, D., additional, Zaharie, M., additional, Glodeanu, A.D., additional, Carstea, A.P., additional, Bidviene, J., additional, Riccoboni, D., additional, Semenzato, G., additional, Iliceto, S., additional, and Badano, L.P., additional

Published
2017
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41. P1433In healthy volunteers, the relative contribution of the radial component of right ventricular wall motion to global right ventricular ejection fraction is as important as its longitudinal shortening

Author

Bidviene, J., primary, Surkova, E., additional, Kovacs, A., additional, Lakatos, B., additional, Tokodi, M., additional, Aruta, P., additional, Rodriguez-Zanella, H., additional, Cherata, D.A., additional, Cucchini, U., additional, Ereminiene, E., additional, Vaskelyte, J.J., additional, Iliceto, S., additional, Badano, L.P., additional, and Muraru, D., additional

Published
2017
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42. P1324Fully automated measurements of left atrial volume are highly feasible and accurate compared to expert manual measurements: a comparative multi-center study using a novel automated analysis algorithm

Author

Mihaila, S., primary, Cucchini, U., additional, Marzaro, A., additional, Muraru, D., additional, Andras, K., additional, Altiok, E., additional, Vinereanu, D., additional, Sadeghpour, A., additional, Alizadehasl, A., additional, Badano, L.P., additional, and Becker, M., additional

Published
2017
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44. P1362In patients with end stage functional mitral regurgitation, mitral annulus geometry is independent on the ischemic or non-ischemic etiology of left ventricular dysfunction

Author

Aruta, P., primary, Valente, L., additional, Ruozi, N., additional, Mihaila, S., additional, Muraru, D., additional, Palermo, C., additional, Cucchini, U., additional, Rigato, I., additional, Rodriguez Zanella, H., additional, Surkova, E., additional, Bidviene, J., additional, Cherata, D.A., additional, Shehatat, H., additional, Iliceto, S., additional, and Badano, L.P., additional

Published
2017
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45. Quantitative analysis of mitral valve geometry by transthoracic three-dimensional echocardiography: reference values, feasibility and reproducibility

Author

Muraru, D, Cattarina, M, Dal Bianco, L, Peluso, D, Zoppellaro, G, Segafredo, B, Calore, C, Cucchini, U, Iliceto, S, Badano, L, Muraru D, Cattarina M, Dal Bianco L, Peluso D, Zoppellaro G, Segafredo B, Calore C, Cucchini U, Iliceto S, Badano L, Muraru, D, Cattarina, M, Dal Bianco, L, Peluso, D, Zoppellaro, G, Segafredo, B, Calore, C, Cucchini, U, Iliceto, S, Badano, L, Muraru D, Cattarina M, Dal Bianco L, Peluso D, Zoppellaro G, Segafredo B, Calore C, Cucchini U, Iliceto S, and Badano L

Abstract

Background: Quantitative analysis of mitral valve (MV) can discriminate among various mechanisms causing valve insufficiency. There are no established reference values for MV geometry, nor data on its feasibility and reproducibility with latest transthoracic 3D echocardiography (3DTTE). Methods: Eighty-one consecutive healthy volunteers (43+13 years, range 18-70; 33 men) with good apical window underwent a 3D full-volume acquisition of MV apparatus (32+2 vps) using Vivid E9 (BT 12, GE Healthcare, Horten, N). MV datasets were analyzed offline using a software recently developed for 3DTTE (TomTec MV assessment 2.0, Unterschleissheim, D). Intra- and inter-observer reproducibility were assessed in 15 subjects and expressed as intraclass correlation coefficients (ICC). Results: Five subjects were excluded due to low quality of 3D dataset with poor MV tracking (feasibility 94%). The average analysis time of one dataset (including manual editing) was 2’. Reference values of MV parameters and their reproducibility are reported in Table. Leaflet tenting and annulus measures were positively correlated with body surface area (BSA, r=0.34-0.53, p , 0.001), but not with age. After correcting for BSA, there were no gender differences in MV parameters. Conclusion: Quantitative analysis of MV by 3DTTE is highly feasible and reproducible, and reference values are reported. Our findings may support the implementation of MV quantitative analysis by 3DTTE in clinical settings.

Published
2012

46. Two-dimensional assessment of tricuspid annulus dynamics and diameters: study for new reference values

Author

Miglioranza, MH, Muraru, D, Peluso, D, Cucchini, U, Mihaila, S, Naso, P, Puma, L, Kocabay, G, Iliceto, S, Badano, L, Miglioranza, M, Muraru, D, Peluso, D, Cucchini, U, Mihaila, S, Naso, P, Puma, L, Kocabay, G, Iliceto, S, and Badano, L

Abstract

Background: Tricuspid annulus (TA) size and function plays an important role in decision-making process about the need of associated TA annuloplasty during left sided cardiac surgery. Recommendations about echo assessment of TA don't indicate the view and the timing where TA should be measured. Our aim was to study TA diameters and shortening in different 2D TTE views to assess the extent of their variability. Methods: Cross-sectional study of normal volunteers. TA was measured from 3 2DTTE views (apical 4-CH, LAX-RV inflow, SAX basal) at 5 time points during cardiac cycle. TA fractional shortening diameter was obtained as (TV opening early-filling – Mid-systole) / TV opening early-filling. Result: 100pts; 42%male; 44±13yrs. TA diameters are in the Table. Fractional shortening of TA was 22±7%, 18±8%, 31±16% in 4-CH, LAX-RV inflow and SAX basal views respectively. Conclusion: This study support new references values for TA evaluation using 2D TTE. Values vary according to 2D TTE view and cardiac cycle time, showing the dynamism and complex geometry of TA

Published
2013

47. Quantitative analysis of mitral valve geometry by transthoracic three-dimensional echocardiography: reference values, feasibility and reproducibility

Author

Muraru D, Cattarina M, Dal Bianco L, Peluso D, Zoppellaro G, Segafredo B, Calore C, Cucchini U, Iliceto S, Badano L, Muraru, D, Cattarina, M, Dal Bianco, L, Peluso, D, Zoppellaro, G, Segafredo, B, Calore, C, Cucchini, U, Iliceto, S, and Badano, L

Subjects
mitral valve, healthy volunteers
Abstract

Background: Quantitative analysis of mitral valve (MV) can discriminate among various mechanisms causing valve insufficiency. There are no established reference values for MV geometry, nor data on its feasibility and reproducibility with latest transthoracic 3D echocardiography (3DTTE). Methods: Eighty-one consecutive healthy volunteers (43+13 years, range 18-70; 33 men) with good apical window underwent a 3D full-volume acquisition of MV apparatus (32+2 vps) using Vivid E9 (BT 12, GE Healthcare, Horten, N). MV datasets were analyzed offline using a software recently developed for 3DTTE (TomTec MV assessment 2.0, Unterschleissheim, D). Intra- and inter-observer reproducibility were assessed in 15 subjects and expressed as intraclass correlation coefficients (ICC). Results: Five subjects were excluded due to low quality of 3D dataset with poor MV tracking (feasibility 94%). The average analysis time of one dataset (including manual editing) was 2’. Reference values of MV parameters and their reproducibility are reported in Table. Leaflet tenting and annulus measures were positively correlated with body surface area (BSA, r=0.34-0.53, p , 0.001), but not with age. After correcting for BSA, there were no gender differences in MV parameters. Conclusion: Quantitative analysis of MV by 3DTTE is highly feasible and reproducible, and reference values are reported. Our findings may support the implementation of MV quantitative analysis by 3DTTE in clinical settings.

Published
2012

48. An unrecognized mechanism of functional tricuspid regurgitation revealed by transthoracic three-dimensional echocardiography

Author

Bidviene, J, Cavalli, G, Cavaliere, A, Genovese, D, Romeo, G, Aruta, P, Cucchini, U, Iliceto, S, Badano, L, Muraru, D, Bidviene Jurate, Cavalli Giacomo, Cavaliere Annachiara, Genovese Davide, Romeo Gabriella, Aruta Patrizia, Cucchini Umberto, Iliceto Sabino, Badano Luigi, Muraru Denisa, Bidviene, J, Cavalli, G, Cavaliere, A, Genovese, D, Romeo, G, Aruta, P, Cucchini, U, Iliceto, S, Badano, L, Muraru, D, Bidviene Jurate, Cavalli Giacomo, Cavaliere Annachiara, Genovese Davide, Romeo Gabriella, Aruta Patrizia, Cucchini Umberto, Iliceto Sabino, Badano Luigi, and Muraru Denisa

Published
2016

49. Two-dimensional assessment of left atrial volume might be inaccurate, mainly at higher volumes and in complex left atrial shapes

Author

Mihaila, S, Velcea, A, Andronic, A, Matei, L, Muraru, D, Cucchini, U, Marcu, S, Badano, L, Vinereanu, D, Mihaila Sorina, Velcea A, Andronic A, Matei Ll, Muraru Denisa, Cucchini Umberto, Marcu S, Badano Luigi, Vinereanu D, Mihaila, S, Velcea, A, Andronic, A, Matei, L, Muraru, D, Cucchini, U, Marcu, S, Badano, L, Vinereanu, D, Mihaila Sorina, Velcea A, Andronic A, Matei Ll, Muraru Denisa, Cucchini Umberto, Marcu S, Badano Luigi, and Vinereanu D

Published
2016

50. Left ventricular remodeling after a first myocardial infarction in patients with preserved ejection fraction at discharge

Author

Volpi, C, Altman, M, Annabi, M, Abouchakra, L, Cucchini, U, Muraru, D, Badano, L, Ernande, L, Derumeaux, G, Volpi Chiara, Altman M, Annabi Ms, Abouchakra L, Cucchini Umberto, Muraru Denisa, Badano Luigi, Ernande L, Derumeaux G, Volpi, C, Altman, M, Annabi, M, Abouchakra, L, Cucchini, U, Muraru, D, Badano, L, Ernande, L, Derumeaux, G, Volpi Chiara, Altman M, Annabi Ms, Abouchakra L, Cucchini Umberto, Muraru Denisa, Badano Luigi, Ernande L, and Derumeaux G

Published
2016

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