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2. Association of Circulating Proinflammatory and Anti-inflammatory Protein Biomarkers in Extremely Preterm Born Children with Subsequent Brain Magnetic Resonance Imaging Volumes and Cognitive Function at Age 10 Years

Author

Ware, Janice, Coster, Taryn, Hanson, Brandi, Wilson, Rachel, McGhee, Kirsten, Lee, Patricia, Asgarian, Aimee, Sadhwani, Anjali, Perrin, Ellen, Neger, Emily, Mattern, Kathryn, Walkowiak, Jenifer, Barron, Susan, Shah, Bhavesh, Singh, Rachana, Smith, Anne, Klein, Deborah, McQuiston, Susan, Venuti, Lauren, Powers, Beth, Foley, Ann, Dessureau, Brian, Wood, Molly, Damon-Minow, Jill, Ehrenkranz, Richard, Benjamin, Jennifer, Romano, Elaine, Tsatsanis, Kathy, Chawarska, Katarzyna, Kim, Sophy, Dieterich, Susan, Bearrs, Karen, Peters, Nancy, Brown, Patricia, Ansusinha, Emily, Waldrep, Ellen, Friedman, Jackie, Hounshell, Gail, Allred, Debbie, Engelke, Stephen C., Darden-Saad, Nancy, Stainback, Gary, Warner, Diane, Wereszczak, Janice, Bernhardt, Janice, McKeeman, Joni, Meyer, Echo, Pastyrnak, Steve, Rathbun, Julie, Nota, Sarah, Crumb, Teri, Lenski, Madeleine, Weiland, Deborah, Lloyd, Megan, Hunter, Scott, Msall, Michael, Ramoskaite, Rugile, Wiggins, Suzanne, Washington, Krissy, Martin, Ryan, Prendergast, Barbara, Scott, Megan, Klarr, Judith, Kring, Beth, DeRidder, Jennifer, Vogt, Kelly, Yamamoto, Hidemi, Ryan, Stanthia, Junaid, Damilola, Dawood, Hassan, Beatty, Noah, Luu, Ngan, Tang, Vanessa, Sassi, Rosaria Rita, Pasicznyk, Jenna-Malia, Kuban, Karl C.K., Jara, Hernan, O'Shea, T. Michael, Heeren, Timothy, Joseph, Robert M., Fichorova, Raina N., Alshamrani, Khalid, Aakil, Adam, Beaulieu, Forrest, Horn, Mitchell, Douglass, Laurie M., Frazier, Jean A., Hirtz, Deborah, Rollins, Julie Vanier, Cochran, David, and Paneth, Nigel

Published
2019
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3. Among Children Born Extremely Preterm a Higher Level of Circulating Neurotrophins Is Associated with Lower Risk of Cognitive Impairment at School Age

Author

Ware, Janice, Coster, Taryn, Hanson, Brandi, Wilson, Rachel, McGhee, Kirsten, Lee, Patricia, Asgarian, Aimee, Sadhwani, Anjali, Perrin, Ellen, Neger, Emily, Mattern, Kathryn, Walkowiak, Jenifer, Barron, Susan, Shah, Bhavesh, Singh, Rachana, Smith, Anne, Klein, Deborah, McQuiston, Susan, Venuti, Lauren, Powers, Beth, Foley, Ann, Dessureau, Brian, Wood, Molly, Damon-Minow, Jill, Ehrenkranz, Richard, Benjamin, Jennifer, Romano, Elaine, Tsatsanis, Kathy, Chawarska, Katarzyna, Kim, Sophy, Dieterich, Susan, Bearrs, Karen, Peters, Nancy, Brown, Patricia, Ansusinha, Emily, Waldrep, Ellen, Friedman, Jackie, Hounshell, Gail, Allred, Debbie, Engelke, Stephen C., Darden-Saad, Nancy, Stainback, Gary, Warner, Diane, Wereszczak, Janice, Bernhardt, Janice, McKeeman, Joni, Meyer, Echo, Pastyrnak, Steve, Rathbun, Julie, Nota, Sarah, Crumb, Teri, Lenski, Madeleine, Weiland, Deborah, Lloyd, Megan, Hunter, Scott, Msall, Michael, Ramoskaite, Rugile, Wiggins, Suzanne, Washington, Krissy, Martin, Ryan, Prendergast, Barbara, Scott, Megan, Klarr, Judith, Kring, Beth, DeRidder, Jennifer, Vogt, Kelly, Yamamoto, Hidemi, Ryan, Stanthia, Junaid, Damilola, Dawood, Hassan, Beatty, Noah, Luu, Ngan, Tang, Vanessa, Sassi, Rosaria Rita, Pasicznyk, Jenna-Malia, Kuban, Karl C.K., Heeren, Timothy, O'Shea, T. Michael, Joseph, Robert M., Fichorova, Raina N., Douglass, Laurie, Jara, Hernan, Frazier, Jean A., Hirtz, Deborah, Taylor, H. Gerry, Rollins, Julie Vanier, and Paneth, Nigel

Published
2018
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4. Neurocognitive Outcomes at 10 Years of Age in Extremely Preterm Newborns with Late-Onset Bacteremia

Author

Ware, Janice, Coster, Taryn, Hanson, Brandi, Wilson, Rachel, McGhee, Kirsten, Lee, Patricia, Asgarian, Aimee, Sadhwani, Anjali, Perrin, Ellen, Neger, Emily, Mattern, Kathryn, Walkowiak, Jenifer, Barron, Susan, Shah, Bhavesh, Singh, Rachana, Smith, Anne, Klein, Deborah, McQuiston, Susan, Venuti, Lauren, Powers, Beth, Foley, Ann, Dessureau, Brian, Wood, Molly, Damon-Minow, Jill, Ehrenkranz, Richard, Benjamin, Jennifer, Romano, Elaine, Tsatsanis, Kathy, Chawarska, Katarzyna, Kim, Sophy, Dieterich, Susan, Bearrs, Karen, Peters, Nancy, Brown, Patricia, Ansusinha, Emily, Waldrep, Ellen, Friedman, Jackie, Hounshell, Gail, Allred, Debbie, Engelke, Stephen C., Darden-Saad, Nancy, Stainback, Gary, Warner, Diane, Wereszczak, Janice, Bernhardt, Janice, McKeeman, Joni, Meyer, Echo, Pastyrnak, Steve, Rathbun, Julie, Nota, Sarah, Crumb, Teri, Lenski, Madeleine, Weiland, Deborah, Lloyd, Megan, Hunter, Scott, Msall, Michael, Ramoskaite, Rugile, Wiggins, Suzanne, Washington, Krissy, Martin, Ryan, Prendergast, Barbara, Scott, Megan, Klarr, Judith, Kring, Beth, DeRidder, Jennifer, Vogt, Kelly, Bright, H. Reeve, Babata, Kikelomo, Allred, Elizabeth N., Erdei, Carmina, Kuban, Karl C.K., Joseph, Robert M., O'Shea, T. Michael, Leviton, Alan, and Dammann, Olaf

Published
2017
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5. The Relationship of Maternal Prepregnancy Body Mass Index and Pregnancy Weight Gain to Neurocognitive Function at Age 10 Years among Children Born Extremely Preterm

Author

Shah, Bhavesh, Singh, Rachana, Smith, Anne, Klein, Deborah, McQuiston, Susan, Rollins, Julie, Douglass, Laurie, Ware, Janice, Coster, Taryn, Henson, Brandi, Wilson, Rachel, McGhee, Kirsten, Lee, Patricia, Asgarian, Aimee, Sadhwani, Anjali, Perrin, Ellen, Neger, Emily, Mattern, Kathryn, Walkowiak, Jenifer, Barron, Susan, Frazier, Jean, Venuti, Lauren, Powers, Beth, Foley, Ann, Dessureau, Brian, Wood, Molly, Damon-Minow, Jill, Ehrenkranz, Richard, Benjamin, Jennifer, Romano, Elaine, Tsatsanis, Kathy, Chawarska, Katarzyna, Kim, Sophy, Dieterich, Susan, Bearrs, Karen, O'Shea, T. Michael, Peters, Nancy, Brown, Patricia, Ansusinha, Emily, Waldrep, Ellen, Friedman, Jackie, Hounshell, Gail, Allred, Debbie, Engelke, Stephen C., Darden-Saad, Nancy, Stainback, Gary, Warner, Diane, Wereszczak, Janice, Bernhardt, Janice, McKeeman, Joni, Meyer, Echo, Pastyrnak, Steve, Burdo-Hartman, Wendy, Rathbun, Julie, Nota, Sarah, Crumb, Teri, Lenski, Madeleine, Weiland, Deborah, Lloyd, Megan, Hunter, Scott, Msall, Michael, Ramoskaite, Rugile, Wiggins, Suzanne, Washington, Krissy, Martin, Ryan, Prendergast, Barbara, Scott, Megan, Klarr, Judith, Kring, Beth, DeRidder, Jennifer, Vogt, Kelly, Jensen, Elizabeth T., van der Burg, Jelske W., O'Shea, Thomas M., Joseph, Robert M., Allred, Elizabeth N., Heeren, Tim, Leviton, Alan, and Kuban, Karl C.K.

Published
2017
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6. Girls and Boys Born before 28 Weeks Gestation: Risks of Cognitive, Behavioral, and Neurologic Outcomes at Age 10 Years

Author

Ware, Janice, Coster, Taryn, Hanson, Brandi, Wilson, Rachel, McGhee, Kirsten, Lee, Patricia, Asgarian, Aimee, Sadhwani, Anjali, Perrin, Ellen, Neger, Emily, Mattern, Kathryn, Walkowiak, Jenifer, Barron, Susan, Shah, Bhavesh, Singh, Rachana, Smith, Anne, Klein, Deborah, McQuiston, Susan, Venuti, Lauren, Powers, Beth, Foley, Ann, Dessureau, Brian, Wood, Molly, Damon-Minow, Jill, Ehrenkranz, Richard, Benjamin, Jennifer, Romano, Elaine, Tsatsanis, Kathy, Chawarska, Katarzyna, Kim, Sophy, Dieterich, Susan, Bearrs, Karen, Peters, Nancy, Brown, Patricia, Ansusinha, Emily, Waldrep, Ellen, Friedman, Jackie, Hounshell, Gail, Allred, Debbie, Engelke, Stephen C., Darden-Saad, Nancy, Stainback, Gary, Warner, Diane, Wereszczak, Janice, Bernhardt, Janice, McKeeman, Joni, Meyer, Echo, Pastyrnak, Steve, Rathbun, Julie, Nota, Sarah, Crumb, Teri, Lenski, Madeleine, Weiland, Deborah, Lloyd, Megan, Hunter, Scott, Msall, Michael, Ramoskaite, Rugile, Wiggins, Suzanne, Washington, Krissy, Martin, Ryan, Prendergast, Barbara, Scott, Megan, Klarr, Judith, Kring, Beth, DeRidder, Jennifer, Vogt, Kelly, Kuban, Karl C.K., Joseph, Robert M., O'Shea, Thomas M., Allred, Elizabeth N., Heeren, Timothy, Douglass, Laurie, Stafstrom, Carl E., Jara, Hernan, Frazier, Jean A., Hirtz, Deborah, and Leviton, Alan

Published
2016
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7. Extremely low gestational age and very low birthweight for gestational age are risk factors for autism spectrum disorder in a large cohort study of 10-year-old children born at 23–27 weeks’ gestation

Author

Joseph, Robert M., Korzeniewski, Steven J., Allred, Elizabeth N., OʼShea, Michael T., Heeren, Tim, Frazier, Jean A., Ware, Janice, Hirtz, Deborah, Leviton, Alan, Kuban, Karl, Ware, Janice, Coster, Taryn, Henson, Brandi, Wilson, Rachel, McGhee, Kirsten, Lee, Patricia, Asgarian, Aimee, Sadhwani, Anjali, Perrin, Ellen, Neger, Emily, Mattern, Kathryn, Walkowiak, Jenifer, Barron, Susan, Frazier, Jean, Venuti, Lauren, Powers, Beth, Foley, Ann, Dessureau, Brian, Wood, Molly, Damon-Minow, Jill, Ehrenkranz, Richard, Benjamin, Jennifer, Romano, Elaine, Tsatsanis, Kathy, Chawarska, Katarzyna, Kim, Sophy, Dieterich, Susan, Bearrs, Karen, OʼShea, Michael T., Peters, Nancy, Brown, Patricia, Ansusinha, Emily, Waldrep, Ellen, Friedman, Jackie, Hounshell, Gail, Allred, Debbie, Engelke, Stephen C., Darden-Saad, Nancy, Stainback, Gary, Warner, Diane, Wereszczak, Janice, Bernhardt, Janice, McKeeman, Joni, Meyer, Echo, Pastyrnak, Steve, Burdo-Hartman, Wendy, Rathbun, Julie, Nota, Sarah, Crumb, Teri, Lenski, Madeleine, Weiland, Deborah, Lloyd, Megan, Hunter, Scott, Msall, Michael, Ramoskaite, Rugile, Wiggins, Suzanne, Washington, Krissy, Martin, Ryan, Prendergast, Barbara, Scott, Megan, Klarr, Judith, Kring, Beth, DeRidder, Jennifer, and Vogt, Kelly

Published
2017
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8. Kidney transplantation in children with decreased left ventricular systolic function: a Midwest Pediatric Nephrology Consortium study

Author

Riar, Sandeep K., Mitsnefes, Mark M., Nehus, Edward J., Patel, Hiren P., Steinke, Julia M., Crumb, Teri, Abraham, Elizabeth C., Kamel, Margret W., and Greenbaum, Larry A.

Subjects
Kidney transplantation -- Research -- Health aspects, Chronic kidney failure -- Research -- Risk factors -- Care and treatment -- Patient outcomes, Health
Abstract

Background Left ventricular (LV) systolic dysfunction is a relatively uncommon but serious complication of pediatric chronic kidney disease, and may be related to uremia and uncontrolled hypertension. There is limited information on the strategy for managing these children. In some cases, combined heart-kidney transplant may be considered or kidney transplant delayed until cardiac function improves. It is unknown whether these patients are at increased risk for poor outcomes after kidney transplantation. Methods We conducted a retrospective, multicenter study on the outcomes of children with severe and symptomatic cardiomyopathy who underwent kidney transplantation. Results Eleven patients receiving maintenance dialysis with systolic dysfunction underwent kidney transplantation without simultaneous heart transplant. Nine patients had congestive heart failure in the pre-transplant period. There were no identified complications post-transplant related to the underlying cardiac dysfunction. LV systolic function normalized in all patients and the mean shortening fraction increased from 19.0 ± 4.6 % to 32.0 ± 4.4 % (p < 0.0001). Conclusions Kidney transplantation should be considered for children receiving maintenance dialysis with severe LV dysfunction., Author(s): Sandeep K. Riar[sup.1] , Mark M. Mitsnefes[sup.2] , Edward J. Nehus[sup.2] , Hiren P. Patel[sup.3] , Julia M. Steinke[sup.4] , Teri Crumb[sup.4] , Elizabeth C. Abraham[sup.5] , Margret W. [...]

Published
2015
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10. Extremely low gestational age and very low birthweight for gestational age are risk factors for autism spectrum disorder in a large cohort study of 10-year-old children born at 23-27 weeks’ gestation

Author

Ware, Janice, Coster, Taryn, Henson, Brandi, Wilson, Rachel, McGhee, Kirsten, Lee, Patricia, Asgarian, Aimee, Sadhwani, Anjali, Perrin, Ellen, Neger, Emily, Mattern, Kathryn, Walkowiak, Jenifer, Barron, Susan, Frazier, Jean, Venuti, Lauren, Powers, Beth, Foley, Ann, Dessureau, Brian, Wood, Molly, Damon-Minow, Jill, Ehrenkranz, Richard, Benjamin, Jennifer, Romano, Elaine, Tsatsanis, Kathy, Chawarska, Katarzyna, Kim, Sophy, Dieterich, Susan, Bearrs, Karen, O’Shea, T. Michael, Peters, Nancy, Brown, Patricia, Ansusinha, Emily, Waldrep, Ellen, Friedman, Jackie, Hounshell, Gail, Allred, Debbie, Engelke, Stephen C., Darden-Saad, Nancy, Stainback, Gary, Warner, Diane, Wereszczak, Janice, Bernhardt, Janice, McKeeman, Joni, Meyer, Echo, Pastyrnak, Steve, Burdo-Hartman, Wendy, Rathbun, Julie, Nota, Sarah, Crumb, Teri, Lenski, Madeleine, Weiland, Deborah, Lloyd, Megan, Hunter, Scott, Msall, Michael, Ramoskaite, Rugile, Wiggins, Suzanne, Washington, Krissy, Martin, Ryan, Prendergast, Barbara, Scott, Megan, Klarr, Judith, Kring, Beth, DeRidder, Jennifer, Vogt, Kelly, Joseph, Robert M., Korzeniewski, Steven J., Allred, Elizabeth N., Heeren, Tim, Frazier, Jean A., Hirtz, Deborah, Leviton, Alan, and Kuban, Karl

Published
2017
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16. Association of Circulating Proinflammatory and Anti-inflammatory Protein Biomarkers in Extremely Preterm Born Children with Subsequent Brain Magnetic Resonance Imaging Volumes and Cognitive Function at Age 10 Years

Author

Kuban, Karl C.K., primary, Jara, Hernan, additional, O'Shea, T. Michael, additional, Heeren, Timothy, additional, Joseph, Robert M., additional, Fichorova, Raina N., additional, Alshamrani, Khalid, additional, Aakil, Adam, additional, Beaulieu, Forrest, additional, Horn, Mitchell, additional, Douglass, Laurie M., additional, Frazier, Jean A., additional, Hirtz, Deborah, additional, Rollins, Julie Vanier, additional, Cochran, David, additional, Paneth, Nigel, additional, Ware, Janice, additional, Coster, Taryn, additional, Hanson, Brandi, additional, Wilson, Rachel, additional, McGhee, Kirsten, additional, Lee, Patricia, additional, Asgarian, Aimee, additional, Sadhwani, Anjali, additional, Perrin, Ellen, additional, Neger, Emily, additional, Mattern, Kathryn, additional, Walkowiak, Jenifer, additional, Barron, Susan, additional, Shah, Bhavesh, additional, Singh, Rachana, additional, Smith, Anne, additional, Klein, Deborah, additional, McQuiston, Susan, additional, Venuti, Lauren, additional, Powers, Beth, additional, Foley, Ann, additional, Dessureau, Brian, additional, Wood, Molly, additional, Damon-Minow, Jill, additional, Ehrenkranz, Richard, additional, Benjamin, Jennifer, additional, Romano, Elaine, additional, Tsatsanis, Kathy, additional, Chawarska, Katarzyna, additional, Kim, Sophy, additional, Dieterich, Susan, additional, Bearrs, Karen, additional, Peters, Nancy, additional, Brown, Patricia, additional, Ansusinha, Emily, additional, Waldrep, Ellen, additional, Friedman, Jackie, additional, Hounshell, Gail, additional, Allred, Debbie, additional, Engelke, Stephen C., additional, Darden-Saad, Nancy, additional, Stainback, Gary, additional, Warner, Diane, additional, Wereszczak, Janice, additional, Bernhardt, Janice, additional, McKeeman, Joni, additional, Meyer, Echo, additional, Pastyrnak, Steve, additional, Rathbun, Julie, additional, Nota, Sarah, additional, Crumb, Teri, additional, Lenski, Madeleine, additional, Weiland, Deborah, additional, Lloyd, Megan, additional, Hunter, Scott, additional, Msall, Michael, additional, Ramoskaite, Rugile, additional, Wiggins, Suzanne, additional, Washington, Krissy, additional, Martin, Ryan, additional, Prendergast, Barbara, additional, Scott, Megan, additional, Klarr, Judith, additional, Kring, Beth, additional, DeRidder, Jennifer, additional, Vogt, Kelly, additional, Yamamoto, Hidemi, additional, Ryan, Stanthia, additional, Junaid, Damilola, additional, Dawood, Hassan, additional, Beatty, Noah, additional, Luu, Ngan, additional, Tang, Vanessa, additional, Sassi, Rosaria Rita, additional, and Pasicznyk, Jenna-Malia, additional

Published
2019
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17. Extremely low gestational age and very low birthweight for gestational age are risk factors for autism spectrum disorder in a large cohort study of 10-year-old children born at 23-27 weeks’ gestation

Author

Martin, Ryan, Ansusinha, Emily, Nota, Sarah, Stainback, Gary, Frazier, Jean A., Barron, Susan, Wood, Molly, Wereszczak, Janice, Washington, Krissy, Darden-Saad, Nancy, Burdo-Hartman, Wendy, Powers, Beth, Kring, Beth, Joseph, Robert M., Waldrep, Ellen, Crumb, Teri, Friedman, Jackie, Hirtz, Deborah, Mattern, Kathryn, Hounshell, Gail, Engelke, Stephen C., Dessureau, Brian, Sadhwani, Anjali, Ramoskaite, Rugile, Bearrs, Karen, O'Shea, T. Michael, Foley, Ann, Venuti, Lauren, Ware, Janice, Heeren, Tim, DeRidder, Jennifer, Hunter, Scott, Kim, Sophy, Rathbun, Julie, Pastyrnak, Steve, Peters, Nancy, Leviton, Alan, Wilson, Rachel, Bernhardt, Janice, Wiggins, Suzanne, Walkowiak, Jenifer, Romano, Elaine, Warner, Diane, Chawarska, Katarzyna, Lee, Patricia, Klarr, Judith, Kuban, Karl, Benjamin, Jennifer, Weiland, Deborah, McGhee, Kirsten, Dieterich, Susan, Prendergast, Barbara, Henson, Brandi, Allred, Elizabeth N., Allred, Debbie, Meyer, Echo, McKeeman, Joni, Coster, Taryn, Vogt, Kelly, Scott, Megan, Msall, Michael, Perrin, Ellen, Lenski, Madeleine, Tsatsanis, Kathy, Lloyd, Megan, Ehrenkranz, Richard, Neger, Emily, Asgarian, Aimee, Brown, Patricia, Damon-Minow, Jill, and Korzeniewski, Steven J.

Subjects
mental disorders, behavioral disciplines and activities
Abstract

No prospective cohort study of high-risk children has used rigorous exposure assessment and optimal diagnostic procedures to examine the perinatal antecedents of autism spectrum disorder (ASD), separately among those with and without cognitive impairment.

Published
2017
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18. The Relationship of Maternal Prepregnancy Body Mass Index and Pregnancy Weight Gain to Neurocognitive Function at Age 10 Years among Children Born Extremely Preterm

Author

McQuiston, Susan, Dessureau, Brian, Peters, Nancy, Lenski, Madeleine, Venuti, Lauren, Jensen, Elizabeth T., Martin, Ryan, Rollins, Julie, Allred, Elizabeth N., Prendergast, Barbara, Asgarian, Aimee, Frazier, Jean, Douglass, Laurie, Sadhwani, Anjali, Damon-Minow, Jill, Allred, Debbie, Singh, Rachana, Wiggins, Suzanne, Kring, Beth, Scott, Megan, van der Burg, Jelske W., Wereszczak, Janice, Ansusinha, Emily, O'Shea, Thomas M., Bernhardt, Janice, Tsatsanis, Kathy, DeRidder, Jennifer, Coster, Taryn, Dieterich, Susan, Perrin, Ellen, Benjamin, Jennifer, Bearrs, Karen, Foley, Ann, Shah, Bhavesh, Walkowiak, Jenifer, Meyer, Echo, Joseph, Robert M., Romano, Elaine, Wilson, Rachel, McGhee, Kirsten, Wood, Molly, Waldrep, Ellen, Neger, Emily, Leviton, Alan, Klarr, Judith, Ehrenkranz, Richard, Engelke, Stephen C., Chawarska, Katarzyna, McKeeman, Joni, Stainback, Gary, Darden-Saad, Nancy, Heeren, Tim, Friedman, Jackie, Mattern, Kathryn, Warner, Diane, Henson, Brandi, Kuban, Karl C.K., Rathbun, Julie, Weiland, Deborah, Nota, Sarah, Burdo-Hartman, Wendy, Msall, Michael, Klein, Deborah, Hunter, Scott, Vogt, Kelly, Powers, Beth, Kim, Sophy, Barron, Susan, Ramoskaite, Rugile, Crumb, Teri, Ware, Janice, Brown, Patricia, Pastyrnak, Steve, Washington, Krissy, Hounshell, Gail, O'Shea, T. Michael, Lee, Patricia, Smith, Anne, and Lloyd, Megan

Abstract

OBJECTIVE: To assess the association between maternal prepregnancy body mass index and adequacy of pregnancy weight gain in relation to neurocognitive function in school-aged children born extremely preterm. STUDY DESIGN: Study participants were 535 ten-year-old children enrolled previously in the prospective multicenter Extremely Low Gestational Age Newborns cohort study who were products of singleton pregnancies. Soon after delivery, mothers provided information about prepregnancy weight. Prepregnancy body mass index and adequacy of weight gain were characterized based on this information. Children underwent a neurocognitive evaluation at 10 years of age. RESULTS: Maternal prepregnancy obesity was associated with increased odds of a lower score for Differential Ability Scales-II Verbal IQ, for Developmental Neuropsychological Assessment-II measures of processing speed and visual fine motor control, and for Wechsler Individual Achievement Test-III Spelling. Children born to mothers who gained an excessive amount of weight were at increased odds of a low score on the Oral and Written Language Scales Oral Expression assessment. Conversely, children whose mother did not gain an adequate amount of weight were at increased odds of a lower score on the Oral and Written Language Scales Oral Expression and Wechsler Individual Achievement Test-III Word Reading assessments. CONCLUSION: In this cohort of infants born extremely preterm, maternal obesity was associated with poorer performance on some assessments of neurocognitive function. Our findings are consistent with the observational and experimental literature and suggest that opportunities may exist to mitigate risk through education and behavioral intervention before pregnancy.

Published
2017
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19. Among Children Born Extremely Preterm a Higher Level of Circulating Neurotrophins Is Associated with Lower Risk of Cognitive Impairment at School Age

Author

Kuban, Karl C.K., primary, Heeren, Timothy, additional, O'Shea, T. Michael, additional, Joseph, Robert M., additional, Fichorova, Raina N., additional, Douglass, Laurie, additional, Jara, Hernan, additional, Frazier, Jean A., additional, Hirtz, Deborah, additional, Taylor, H. Gerry, additional, Rollins, Julie Vanier, additional, Paneth, Nigel, additional, Ware, Janice, additional, Coster, Taryn, additional, Hanson, Brandi, additional, Wilson, Rachel, additional, McGhee, Kirsten, additional, Lee, Patricia, additional, Asgarian, Aimee, additional, Sadhwani, Anjali, additional, Perrin, Ellen, additional, Neger, Emily, additional, Mattern, Kathryn, additional, Walkowiak, Jenifer, additional, Barron, Susan, additional, Shah, Bhavesh, additional, Singh, Rachana, additional, Smith, Anne, additional, Klein, Deborah, additional, McQuiston, Susan, additional, Venuti, Lauren, additional, Powers, Beth, additional, Foley, Ann, additional, Dessureau, Brian, additional, Wood, Molly, additional, Damon-Minow, Jill, additional, Ehrenkranz, Richard, additional, Benjamin, Jennifer, additional, Romano, Elaine, additional, Tsatsanis, Kathy, additional, Chawarska, Katarzyna, additional, Kim, Sophy, additional, Dieterich, Susan, additional, Bearrs, Karen, additional, Peters, Nancy, additional, Brown, Patricia, additional, Ansusinha, Emily, additional, Waldrep, Ellen, additional, Friedman, Jackie, additional, Hounshell, Gail, additional, Allred, Debbie, additional, Engelke, Stephen C., additional, Darden-Saad, Nancy, additional, Stainback, Gary, additional, Warner, Diane, additional, Wereszczak, Janice, additional, Bernhardt, Janice, additional, McKeeman, Joni, additional, Meyer, Echo, additional, Pastyrnak, Steve, additional, Rathbun, Julie, additional, Nota, Sarah, additional, Crumb, Teri, additional, Lenski, Madeleine, additional, Weiland, Deborah, additional, Lloyd, Megan, additional, Hunter, Scott, additional, Msall, Michael, additional, Ramoskaite, Rugile, additional, Wiggins, Suzanne, additional, Washington, Krissy, additional, Martin, Ryan, additional, Prendergast, Barbara, additional, Scott, Megan, additional, Klarr, Judith, additional, Kring, Beth, additional, DeRidder, Jennifer, additional, Vogt, Kelly, additional, Yamamoto, Hidemi, additional, Ryan, Stanthia, additional, Junaid, Damilola, additional, Dawood, Hassan, additional, Beatty, Noah, additional, Luu, Ngan, additional, Tang, Vanessa, additional, Sassi, Rosaria Rita, additional, and Pasicznyk, Jenna-Malia, additional

Published
2018
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21. Hand Preference and Cognitive, Motor, and Behavioral Functioning in 10-Year-Old Extremely Preterm Children

Author

Burnett, Alice C., primary, Anderson, Peter J., additional, Joseph, Robert M., additional, Allred, Elizabeth N., additional, O'Shea, T. Michael, additional, Kuban, Karl C.K., additional, Leviton, Alan, additional, Shah, Bhavesh, additional, Singh, Rachana, additional, Smith, Anne, additional, Klein, Deborah, additional, McQuiston, Susan, additional, Rollins, Julie, additional, Douglass, Laurie, additional, Ware, Janice, additional, Coster, Taryn, additional, Henson, Brandi, additional, Wilson, Rachel, additional, McGhee, Kirsten, additional, Lee, Patricia, additional, Asgarian, Aimee, additional, Sadhwani, Anjali, additional, Perrin, Ellen, additional, Neger, Emily, additional, Mattern, Kathryn, additional, Walkowiak, Jenifer, additional, Barron, Susan, additional, Frazier, Jean, additional, Venuti, Lauren, additional, Powers, Beth, additional, Foley, Ann, additional, Dessureau, Brian, additional, Wood, Molly, additional, Damon-Minow, Jill, additional, Ehrenkranz, Richard, additional, Benjamin, Jennifer, additional, Romano, Elaine, additional, Tsatsanis, Kathy, additional, Chawarska, Katarzyna, additional, Kim, Sophy, additional, Dieterich, Susan, additional, Bearrs, Karen, additional, Peters, Nancy, additional, Brown, Patricia, additional, Ansusinha, Emily, additional, Waldrep, Ellen, additional, Friedman, Jackie, additional, Hounshell, Gail, additional, Allred, Debbie, additional, Engelke, Stephen C., additional, Darden-Saad, Nancy, additional, Stainback, Gary, additional, Warner, Diane, additional, Wereszczak, Janice, additional, Bernhardt, Janice, additional, McKeeman, Joni, additional, Meyer, Echo, additional, Pastyrnak, Steve, additional, Burdo-Hartman, Wendy, additional, Rathbun, Julie, additional, Nota, Sarah, additional, Crumb, Teri, additional, Lenski, Madeleine, additional, Weiland, Deborah, additional, Lloyd, Megan, additional, Hunter, Scott, additional, Msall, Michael, additional, Ramoskaite, Rugile, additional, Wiggins, Suzanne, additional, Washington, Krissy, additional, Martin, Ryan, additional, Prendergast, Barbara, additional, Scott, Megan, additional, Klarr, Judith, additional, Kring, Beth, additional, DeRidder, Jennifer, additional, and Vogt, Kelly, additional

Published
2018
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22. Antecedents of Screening Positive for Attention Deficit Hyperactivity Disorder in Ten-Year-Old Children Born Extremely Preterm

Author

Leviton, Alan, primary, Hooper, Stephen R., additional, Hunter, Scott J., additional, Scott, Megan N., additional, Allred, Elizabeth N., additional, Joseph, Robert M., additional, O'Shea, T. Michael, additional, Kuban, Karl, additional, Ware, Janice, additional, Coster, Taryn, additional, Henson, Brandi, additional, Wilson, Rachel, additional, McGhee, Kirsten, additional, Lee, Patricia, additional, Asgarian, Aimee, additional, Sadhwani, Anjali, additional, Perrin, Ellen, additional, Neger, Emily, additional, Mattern, Kathryn, additional, Walkowiak, Jenifer, additional, Barron, Susan, additional, Frazier, Jean, additional, Venuti, Lauren, additional, Powers, Beth, additional, Foley, Ann, additional, Dessureau, Brian, additional, Wood, Molly, additional, Damon-Minow, Jill, additional, Ehrenkranz, Richard, additional, Benjamin, Jennifer, additional, Romano, Elaine, additional, Tsatsanis, Kathy, additional, Chawarska, Katarzyna, additional, Kim, Sophy, additional, Dieterich, Susan, additional, Bearrs, Karen, additional, Peters, Nancy, additional, Brown, Patricia, additional, Ansusinha, Emily, additional, Waldrep, Ellen, additional, Friedman, Jackie, additional, Hounshell, Gail, additional, Allred, Debbie, additional, Engelke, Stephen C., additional, Darden-Saad, Nancy, additional, Stainback, Gary, additional, Warner, Diane, additional, Wereszczak, Janice, additional, Bernhardt, Janice, additional, McKeeman, Joni, additional, Meyer, Echo, additional, Pastyrnak, Steve, additional, Burdo-Hartman, Wendy, additional, Rathbun, Julie, additional, Nota, Sarah, additional, Crumb, Teri, additional, Lenski, Madeleine, additional, Weiland, Deborah, additional, Lloyd, Megan, additional, Hunter, Scott, additional, Msall, Michael, additional, Ramoskaite, Rugile, additional, Wiggins, Suzanne, additional, Washington, Krissy, additional, Martin, Ryan, additional, Prendergast, Barbara, additional, Scott, Megan, additional, Klarr, Judith, additional, Kring, Beth, additional, DeRidder, Jennifer, additional, and Vogt, Kelly, additional

Published
2018
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23. Co-occurrence and Severity of Neurodevelopmental Burden (Cognitive Impairment, Cerebral Palsy, Autism Spectrum Disorder, and Epilepsy) at Age Ten Years in Children Born Extremely Preterm

Author

Hirschberger, Rachel G., primary, Kuban, Karl C.K., additional, O'Shea, Thomas M., additional, Joseph, Robert M., additional, Heeren, Tim, additional, Douglass, Laurie M., additional, Stafstrom, Carl E., additional, Jara, Hernan, additional, Frazier, Jean A., additional, Hirtz, Deborah, additional, Rollins, Julie V., additional, Paneth, Nigel, additional, Ware, Janice, additional, Coster, Taryn, additional, Hanson, Brandi, additional, Wilson, Rachel, additional, McGhee, Kirsten, additional, Lee, Patricia, additional, Asgarian, Aimee, additional, Sadhwani, Anjali, additional, Perrin, Ellen, additional, Neger, Emily, additional, Mattern, Kathryn, additional, Walkowiak, Jenifer, additional, Barron, Susan, additional, Shah, Bhavesh, additional, Singh, Rachana, additional, Smith, Anne, additional, Klein, Deborah, additional, McQuiston, Susan, additional, Venuti, Lauren, additional, Powers, Beth, additional, Foley, Ann, additional, Dessureau, Brian, additional, Wood, Molly, additional, Damon-Minow, Jill, additional, Ehrenkranz, Richard, additional, Benjamin, Jennifer, additional, Romano, Elaine, additional, Tsatsanis, Kathy, additional, Chawarska, Katarzyna, additional, Kim, Sophy, additional, Dieterich, Susan, additional, Bearrs, Karen, additional, Peters, Nancy, additional, Brown, Patricia, additional, Ansusinha, Emily, additional, Waldrep, Ellen, additional, Friedman, Jackie, additional, Hounshell, Gail, additional, Allred, Debbie, additional, Engelke, Stephen C., additional, Darden-Saad, Nancy, additional, Stainback, Gary, additional, Warner, Diane, additional, Wereszczak, Janice, additional, Bernhardt, Janice, additional, McKeeman, Joni, additional, Meyer, Echo, additional, Pastyrnak, Steve, additional, Rathbun, Julie, additional, Nota, Sarah, additional, Crumb, Teri, additional, Lenski, Madeleine, additional, Weiland, Deborah, additional, Lloyd, Megan, additional, Hunter, Scott, additional, Msall, Michael, additional, Ramoskaite, Rugile, additional, Wiggins, Suzanne, additional, Washington, Krissy, additional, Martin, Ryan, additional, Prendergast, Barbara, additional, Scott, Megan, additional, Klarr, Judith, additional, Kring, Beth, additional, DeRidder, Jennifer, additional, and Vogt, Kelly, additional

Published
2018
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24. Neurocognitive Outcomes at 10 Years of Age in Extremely Preterm Newborns with Late-Onset Bacteremia

Author

Bright, H. Reeve, primary, Babata, Kikelomo, additional, Allred, Elizabeth N., additional, Erdei, Carmina, additional, Kuban, Karl C.K., additional, Joseph, Robert M., additional, O'Shea, T. Michael, additional, Leviton, Alan, additional, Dammann, Olaf, additional, Ware, Janice, additional, Coster, Taryn, additional, Hanson, Brandi, additional, Wilson, Rachel, additional, McGhee, Kirsten, additional, Lee, Patricia, additional, Asgarian, Aimee, additional, Sadhwani, Anjali, additional, Perrin, Ellen, additional, Neger, Emily, additional, Mattern, Kathryn, additional, Walkowiak, Jenifer, additional, Barron, Susan, additional, Shah, Bhavesh, additional, Singh, Rachana, additional, Smith, Anne, additional, Klein, Deborah, additional, McQuiston, Susan, additional, Venuti, Lauren, additional, Powers, Beth, additional, Foley, Ann, additional, Dessureau, Brian, additional, Wood, Molly, additional, Damon-Minow, Jill, additional, Ehrenkranz, Richard, additional, Benjamin, Jennifer, additional, Romano, Elaine, additional, Tsatsanis, Kathy, additional, Chawarska, Katarzyna, additional, Kim, Sophy, additional, Dieterich, Susan, additional, Bearrs, Karen, additional, Peters, Nancy, additional, Brown, Patricia, additional, Ansusinha, Emily, additional, Waldrep, Ellen, additional, Friedman, Jackie, additional, Hounshell, Gail, additional, Allred, Debbie, additional, Engelke, Stephen C., additional, Darden-Saad, Nancy, additional, Stainback, Gary, additional, Warner, Diane, additional, Wereszczak, Janice, additional, Bernhardt, Janice, additional, McKeeman, Joni, additional, Meyer, Echo, additional, Pastyrnak, Steve, additional, Rathbun, Julie, additional, Nota, Sarah, additional, Crumb, Teri, additional, Lenski, Madeleine, additional, Weiland, Deborah, additional, Lloyd, Megan, additional, Hunter, Scott, additional, Msall, Michael, additional, Ramoskaite, Rugile, additional, Wiggins, Suzanne, additional, Washington, Krissy, additional, Martin, Ryan, additional, Prendergast, Barbara, additional, Scott, Megan, additional, Klarr, Judith, additional, Kring, Beth, additional, DeRidder, Jennifer, additional, and Vogt, Kelly, additional

Published
2017
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25. The Relationship of Maternal Prepregnancy Body Mass Index and Pregnancy Weight Gain to Neurocognitive Function at Age 10 Years among Children Born Extremely Preterm

Author

Jensen, Elizabeth T., primary, van der Burg, Jelske W., additional, O'Shea, Thomas M., additional, Joseph, Robert M., additional, Allred, Elizabeth N., additional, Heeren, Tim, additional, Leviton, Alan, additional, Kuban, Karl C.K., additional, Shah, Bhavesh, additional, Singh, Rachana, additional, Smith, Anne, additional, Klein, Deborah, additional, McQuiston, Susan, additional, Rollins, Julie, additional, Douglass, Laurie, additional, Ware, Janice, additional, Coster, Taryn, additional, Henson, Brandi, additional, Wilson, Rachel, additional, McGhee, Kirsten, additional, Lee, Patricia, additional, Asgarian, Aimee, additional, Sadhwani, Anjali, additional, Perrin, Ellen, additional, Neger, Emily, additional, Mattern, Kathryn, additional, Walkowiak, Jenifer, additional, Barron, Susan, additional, Frazier, Jean, additional, Venuti, Lauren, additional, Powers, Beth, additional, Foley, Ann, additional, Dessureau, Brian, additional, Wood, Molly, additional, Damon-Minow, Jill, additional, Ehrenkranz, Richard, additional, Benjamin, Jennifer, additional, Romano, Elaine, additional, Tsatsanis, Kathy, additional, Chawarska, Katarzyna, additional, Kim, Sophy, additional, Dieterich, Susan, additional, Bearrs, Karen, additional, O'Shea, T. Michael, additional, Peters, Nancy, additional, Brown, Patricia, additional, Ansusinha, Emily, additional, Waldrep, Ellen, additional, Friedman, Jackie, additional, Hounshell, Gail, additional, Allred, Debbie, additional, Engelke, Stephen C., additional, Darden-Saad, Nancy, additional, Stainback, Gary, additional, Warner, Diane, additional, Wereszczak, Janice, additional, Bernhardt, Janice, additional, McKeeman, Joni, additional, Meyer, Echo, additional, Pastyrnak, Steve, additional, Burdo-Hartman, Wendy, additional, Rathbun, Julie, additional, Nota, Sarah, additional, Crumb, Teri, additional, Lenski, Madeleine, additional, Weiland, Deborah, additional, Lloyd, Megan, additional, Hunter, Scott, additional, Msall, Michael, additional, Ramoskaite, Rugile, additional, Wiggins, Suzanne, additional, Washington, Krissy, additional, Martin, Ryan, additional, Prendergast, Barbara, additional, Scott, Megan, additional, Klarr, Judith, additional, Kring, Beth, additional, DeRidder, Jennifer, additional, and Vogt, Kelly, additional

Published
2017
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26. Girls and Boys Born before 28 Weeks Gestation: Risks of Cognitive, Behavioral, and Neurologic Outcomes at Age 10 Years

Author

Kuban, Karl C.K., primary, Joseph, Robert M., additional, O'Shea, Thomas M., additional, Allred, Elizabeth N., additional, Heeren, Timothy, additional, Douglass, Laurie, additional, Stafstrom, Carl E., additional, Jara, Hernan, additional, Frazier, Jean A., additional, Hirtz, Deborah, additional, Leviton, Alan, additional, Ware, Janice, additional, Coster, Taryn, additional, Hanson, Brandi, additional, Wilson, Rachel, additional, McGhee, Kirsten, additional, Lee, Patricia, additional, Asgarian, Aimee, additional, Sadhwani, Anjali, additional, Perrin, Ellen, additional, Neger, Emily, additional, Mattern, Kathryn, additional, Walkowiak, Jenifer, additional, Barron, Susan, additional, Shah, Bhavesh, additional, Singh, Rachana, additional, Smith, Anne, additional, Klein, Deborah, additional, McQuiston, Susan, additional, Venuti, Lauren, additional, Powers, Beth, additional, Foley, Ann, additional, Dessureau, Brian, additional, Wood, Molly, additional, Damon-Minow, Jill, additional, Ehrenkranz, Richard, additional, Benjamin, Jennifer, additional, Romano, Elaine, additional, Tsatsanis, Kathy, additional, Chawarska, Katarzyna, additional, Kim, Sophy, additional, Dieterich, Susan, additional, Bearrs, Karen, additional, Peters, Nancy, additional, Brown, Patricia, additional, Ansusinha, Emily, additional, Waldrep, Ellen, additional, Friedman, Jackie, additional, Hounshell, Gail, additional, Allred, Debbie, additional, Engelke, Stephen C., additional, Darden-Saad, Nancy, additional, Stainback, Gary, additional, Warner, Diane, additional, Wereszczak, Janice, additional, Bernhardt, Janice, additional, McKeeman, Joni, additional, Meyer, Echo, additional, Pastyrnak, Steve, additional, Rathbun, Julie, additional, Nota, Sarah, additional, Crumb, Teri, additional, Lenski, Madeleine, additional, Weiland, Deborah, additional, Lloyd, Megan, additional, Hunter, Scott, additional, Msall, Michael, additional, Ramoskaite, Rugile, additional, Wiggins, Suzanne, additional, Washington, Krissy, additional, Martin, Ryan, additional, Prendergast, Barbara, additional, Scott, Megan, additional, Klarr, Judith, additional, Kring, Beth, additional, DeRidder, Jennifer, additional, and Vogt, Kelly, additional

Published
2016
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28. Hand Preference and Cognitive, Motor, and Behavioral Functioning in 10-Year-Old Extremely Preterm Children

Author

Shah, Bhavesh, Singh, Rachana, Smith, Anne, Klein, Deborah, McQuiston, Susan, Rollins, Julie, Douglass, Laurie, Ware, Janice, Coster, Taryn, Henson, Brandi, Wilson, Rachel, McGhee, Kirsten, Lee, Patricia, Asgarian, Aimee, Sadhwani, Anjali, Perrin, Ellen, Neger, Emily, Mattern, Kathryn, Walkowiak, Jenifer, Barron, Susan, Frazier, Jean, Venuti, Lauren, Powers, Beth, Foley, Ann, Dessureau, Brian, Wood, Molly, Damon-Minow, Jill, Ehrenkranz, Richard, Benjamin, Jennifer, Romano, Elaine, Tsatsanis, Kathy, Chawarska, Katarzyna, Kim, Sophy, Dieterich, Susan, Bearrs, Karen, Peters, Nancy, Brown, Patricia, Ansusinha, Emily, Waldrep, Ellen, Friedman, Jackie, Hounshell, Gail, Allred, Debbie, Engelke, Stephen C., Darden-Saad, Nancy, Stainback, Gary, Warner, Diane, Wereszczak, Janice, Bernhardt, Janice, McKeeman, Joni, Meyer, Echo, Pastyrnak, Steve, Burdo-Hartman, Wendy, Rathbun, Julie, Nota, Sarah, Crumb, Teri, Lenski, Madeleine, Weiland, Deborah, Lloyd, Megan, Hunter, Scott, Msall, Michael, Ramoskaite, Rugile, Wiggins, Suzanne, Washington, Krissy, Martin, Ryan, Prendergast, Barbara, Scott, Megan, Klarr, Judith, Kring, Beth, DeRidder, Jennifer, Vogt, Kelly, Burnett, Alice C., Anderson, Peter J., Joseph, Robert M., Allred, Elizabeth N., O'Shea, T. Michael, Kuban, Karl C.K., and Leviton, Alan

Published
2018
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30. Sonographic assessment of renal size and growth in premature infants.

Author

Venrooij, Natalie, Junewick, Joseph, Gelfand, Steven, Davis, Alan, Crumb, Teri, and Bunchman, Timothy

Subjects
KIDNEY disease risk factors, PREMATURE infant diseases, LOW birth weight, DIAGNOSTIC ultrasonic imaging, NEONATOLOGY, DIAGNOSIS, PHYSIOLOGY
Abstract

Low birth-weight infants are at risk for renal disease when renal insults occur in the neonatal period. Renal growth as measured by sonography over time is utilized by many nephrologists as predictors of future renal disease. To identify infants at risk by defining normal renal growth for the very premature infant. Renal growth was evaluated in 30 infants whose birth weight was 1,500 g or less and gestational age was <31 weeks. During a 2-month time period, three US measurements were taken (first week of life, age 28 days, and age 56 days or earlier if discharged). Infants were divided according to birth weight: the extremely low birth-weight group (ELBW) was <1,000 g ( n = 14), and the very low birth-weight group (VLBW) was 1,000–1,500 g ( n = 16). In both groups, the right and left renal lengths were similar. In the ELBW group, the initial mean length was 3.25 cm and grew to 4.16 cm, while the mean volume was 4.85 cm and grew to 10.39 cm. In the VLBW group the initial mean length was 3.69 cm and grew to 4.35 cm while the mean volume was 7.25 cm and grew to 11.83 cm. These data establish normal expected growth for future studies. [ABSTRACT FROM AUTHOR]

Published
2010
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32. Paenibacilluswound infection in a pediatric trauma patient

Author

Mannava, Sindhu V., DeCou, James, Watkins, Daniel J., Crumb, Teri, Pardington, Emily, and Pennington, Elliot C.

Abstract

We report a case of Paenibacilluswound infection in an immunocompetent and otherwise healthy nine-year-old boy who sustained a laceration following an all-terrain vehicle crash. During his course, he failed non-operative management and required multiple wound washouts and a thirty-six-day course of antibiotics. While this pathogen is most known for causing honeybee disease known as American Foulbrood (AFB), Paenibacillushas been implicated in a handful of human wound complications in the post-traumatic setting. This is a rare, opportunistic bacteria that is resistant to many commonly prescribed antibiotics. Less than twenty cases of human Paenibacilluswound infections have been reported in the literature and when they do occur, they often affect immunocompromised patients or those with chronic medical co-morbidities. In the last ten years, there have been four case reports of neonatal sepsis caused by this pathogen. This appears to be the first pediatric Paenibacilluswound infection reported.

Published
2022
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33. Transient Secondary Hypothyroidism and Thyroid Hormone Replacement Therapy in Pediatric Postoperative Cardiopulmonary Bypass.

Author

D Souza TF, Hoshal SG, Albeiruti R, Zambito MP, Zambito GM, Khan FM, Samuel BP, Crumb TL, Rajasekaran S, and Vettukattil JJ

Subjects
Child, Cross-Sectional Studies, Female, Humans, Hypothyroidism pathology, Male, Postoperative Period, Thyrotropin pharmacology, Cardiopulmonary Bypass methods, Hormone Replacement Therapy methods, Hypothyroidism etiology, Thyrotropin therapeutic use
Abstract

Background: To develop an understanding of current practices in the management of transient secondary hypothyroidism in pediatric postoperative cardiopulmonary bypass (CPB) patients., Methods: Electronic survey comprising a 10-item questionnaire was sent to sixty-four high volume pediatric heart centers in the United States and United Kingdom. Survey participants included cardiologists, intensivists, cardiothoracic surgeons, and advanced practice providers. A retrospective chart review was also performed at a large regional referral center in the Midwest on subjects 0-18 years old who underwent CPB from 2005-2015. Information obtained included a unique identifier, date of birth, age, procedure performed, CPB time, date of surgery and date and type of Thyroid Function Test (TFT) ordered., Results: 1,153 individuals from 64 congenital heart centers were contacted via email to participate in the electronic survey. In the 3-month response window, 129 completed surveys were received from cardiologists (55%), intensivists (17%), surgeons (15%), "other" (8%), and advanced practice providers (5%). This yielded a response rate of 11.2%. Of the 129 respondents, only 10 providers routinely order TFTs prior to (n=7) and after (n=1) CPB or when clinically indicated (n=2). All 10 providers order thyroid stimulating hormone test, 7 order thyroxine, and 3 order triiodothyronine. Only 1 provider routinely treats children with prophylactic thyroid hormone replacement therapy after CPB. Our retrospective review included 502 CPB events with 442 unique patients. Of the events, 20 patients received preoperative TFT testing while 11 received postoperative testing., Conclusions: There is a general lack of uniformity in the evaluation, diagnosis, and treatment of transient secondary hypothyroidism in pediatric postoperative CPB patients., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.)

Published
2018
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