131 results on '"Crowe, Paul D."'
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2. Rapid Activation of Protein Kinase C in Isolated Rat Liver Nuclei by Prolactin, a Known Hepatic Mitogen
3. A Lymphotoxin-β-Specific Receptor
4. High-throughput screening for norepinephrine transporter inhibitors using the FLIP[R.sup.Tetra]
5. Scintillation proximity assay as a high-throughput method to identify slowly dissociating nonpeptide ligand binding to the GnRH receptor
6. SUN-LB23 Translational Feasibility of Steroidogenic Factor-1 Antagonists as a Novel Targeted Therapy for Adrenocortical Cancer
7. Kinetics of nonpeptide antagonist binding to the human gonadotropin-releasing hormone receptor: Implications for structure-activity relationships and insurmountable antagonism
8. CRF receptor type 1 and 2 expression and anatomical distribution in the rat colon
9. Differential profile of CRF receptor distribution in the rat stomach and duodenum assessed by newly developed CRF receptor antibodies
10. Prolactin-provoked alterations of cytosolic, membrane, and nuclear protein kinase C following partial hepatectomy
11. Conformational states of the corticotropin releasing factor 1 (CRF1) receptor: detection, and pharmacological evaluation by peptide ligands
12. A lymphotoxin-beta-specific receptor
13. Immunological Characterization and Therapeutic Activity of an Altered-Peptide Ligand, NBI-6024, Based on the Immunodominant Type 1 Diabetes Autoantigen Insulin B-Chain (9-23) Peptide
14. A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin
15. Allosteric and orthosteric binding modes of two nonpeptide human gonadotropin-releasing hormone receptor antagonists
16. Ligand affinity for amino-terminal and juxtamembrane domains of the corticotropin releasing factor type I receptor: regulation by G-protein and nonpeptide antagonists
17. Lead optimization of 2-(piperidin-3-yl)-1H-benzimidazoles: Identification of 2-morpholin- and 2-thiomorpholin-2-yl-1H-benzimidazoles as selective and CNS penetrating H1-antihistamines for insomnia
18. Influence of p Ka on the biotransformation of indene H 1-antihistamines by CYP2D6
19. Identification of a novel selective H 1-antihistamine with optimized pharmacokinetic properties for clinical evaluation in the treatment of insomnia
20. The discovery and structure–activity relationships of 2-(piperidin-3-yl)-1 H-benzimidazoles as selective, CNS penetrating H 1-antihistamines for insomnia
21. Novel benzothiophene H 1-antihistamines for the treatment of insomnia
22. Brain-penetrating 2-aminobenzimidazole H1-antihistamines for the treatment of insomnia
23. Influence of pKa on the biotransformation of indene H1-antihistamines by CYP2D6
24. Identification of a novel selective H1-antihistamine with optimized pharmacokinetic properties for clinical evaluation in the treatment of insomnia
25. The discovery and structure–activity relationships of 2-(piperidin-3-yl)-1H-benzimidazoles as selective, CNS penetrating H1-antihistamines for insomnia
26. Novel benzothiophene H1-antihistamines for the treatment of insomnia
27. Selectivity profiling of novel indene H1-antihistamines for the treatment of insomnia
28. Characterization of Novel Selective H1-Antihistamines for Clinical Evaluation in the Treatment of Insomnia
29. Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: Application to (R)-dimethindene occupancy of central histamine H1receptors
30. Allosteric Ligands for the Corticotropin Releasing Factor Type 1 Receptor Modulate Conformational States Involved in Receptor Activation
31. High-Throughput Screening for Norepinephrine Transporter Inhibitors Using the FLIPRTetra
32. Scintillation Proximity Assay as a High-Throughput Method to Identify Slowly Dissociating Nonpeptide Ligand Binding to the GnRH Receptor
33. Design and Synthesis of Tricyclic Imidazo[4,5-b]pyridin-2-ones as Corticotropin-Releasing Factor-1 Antagonists
34. Differential profile of CRF receptor distribution in the rat stomach and duodenum assessed by newly developed CRF receptor antibodies
35. A novel water-soluble selective CRF1 receptor antagonist, NBI 35965, blunts stress-induced visceral hyperalgesia and colonic motor function in rats
36. Corticotropin releasing factor (CRF) receptors in the upper gastrointestinal (GI) tract of the rat: Mapping of expression using newly developed specific antibodies
37. Mechanism of Corticotropin-Releasing Factor Type I Receptor Regulation by Nonpeptide Antagonists
38. Regulation of murine macrophage proinflammatory and anti-inflammatory cytokines by ligands for peroxisome proliferator-activated receptor-γ: counter-regulatory activity by IFN-γ
39. NBI‐5788, an altered MBP83‐99 peptide, induces a T‐helper 2–like immune response in multiple sclerosis patients
40. A disease-associated cellular immune response in type I diabetics to an immunodominant epitope of insulin
41. A Lymphotoxin-β-Specific Receptor.
42. Nephroblastoma overexpressed gene (NOV) codes for a growth factor that induces protein tyrosine phosphorylation
43. Activation of Mitogen-Activated Protein Kinase Regulates Eotaxin-Induced Eosinophil Migration
44. Differential signaling and hierarchical response thresholds induced by an immunodominant peptide of myelin basic protein and an altered peptide ligand in human T cells
45. T cell recognition motifs of an immunodominant peptide of myelin basic protein in patients with multiple sclerosis: structural requirements and clinical implications
46. Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms
47. Immunosuppressive Phenotype of Corticotropin-Releasing Factor Transgenic Mice Is Reversed by Adrenalectomy
48. Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL1R-rp2)
49. Production of lymphotoxin (LTα) and a soluble dimeric form of its receptor using the baculovirus expression system
50. Prolactin and known modulators of rat splenocytes activate nuclear protein kinase C
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