Search

Background/Aim. Preterm delivery together with insufficient body weight and death cases in newborns is the main issue in obstetrics. About 40% of preterm delivery is caused by infections. The aim of this study was to investigate whether and which bacterial infections of genital tract can be associated with preterm delivery, and depending on when diagnosis was made. Method. The study involved 216 pregnant women. According to pregnancy outcome, two groups were formed. The study group involved 29 pregnant women who had preterm delivery out of which nine were examined in I trimester, eight in II trimester and 12 in III trimester. The control group involved 187 pregnant women out of which 47 were examined in I trimester, 73 in II trimester and 67 in III trimester. Bacteriological examination of vaginal and cervical swabs was done in all pregnant women. Infection was diagnosed by finding bacterial antigen in cervical swabs or positive cultures of vaginal and/or cervical swabs followed by the presence of the increased number of polymorphonuclears in direct microscopic preparation. Results. The results showed that in III trimester of pregnancy vaginal bacterial infection was statistically more common (p = 0.021) in women who had preterm delivery (66.7%) in relation to women who delivered in term (29.9%). In this period of gestation the increased number of polymorphonuclears in DMP of vaginal swabs is more common in the women of the study group (75%) than in the women of the control group (43.3%). Preterm delivery was registered in 16.1% women whose microbiological analyses were done in I trimester, 9.9% women in whom microbiological analyses were done in II trimester and in 15.2% pregnant women microbiologically tested in III trimester. Conclusion. Based on the obtained results it could be concluded that bacterial infections of genital tract and period of gestation when infection is diagnosed have influence on reducing perinatal morbidity and mortality caused by preterm delivery.

The term vein of Galen aneurysm is related to a group of different vascular anomalies, with one common distinction being the dilatation of the vein of Galen. It represents a rear vascular anomaly, whose incidence is yet unknown, although some authors suggest numbers around 1:25000 deliveries. It accounts for only 1% of all intracranial malformations, but the percentage of this anomaly in pediatric populations is up to 30%. In most cases the diagnosis is made postnatal, while antenatal diagnosis, because of the pathophysiology of aneurysm itself, as well as pathophysiology of its possible complications, is made usually during the third trimester, frequently after the 34th week of gestation. The earliest reported diagnosis was made at 25 weeks’ gestation. In this case we present 25-year old gravida, pregnancy at 28th week of gestation with aneurysm, and sonographically detected aneurysm of the vein of Galen, that ended with termination of pregnancy.

TAR Sy is a rare, severe genetic disorder of fetus with a frequency of 1:30-80,000 pregnancies. It is characterized by thrombocytopenia, absence of radius, with presence of thumb with regular position, abnormal position of the hand, possible shortened long bones of the extremities. In 50% of cases the change is mutual. It is most often detected on a routine ultrasound examination of 16-18 gw. Radial ray malformation should be excluded by Differential diagnostic in case when the thumb is missing. A 32 years old patient, second pregnancy, nulliparous, (one missed abortion with 8gw) with 23 weeks of gestation pregnancy, and with no complications until then, was sent to our institution for expert ultrasound examination. At the ultrasound examination, biometry was adequate to 23 weeks of gestation, apart from the length of the ulna. The lower extremities were of regular morphologies as well as the upper arms, the bones of perfect homogeneity. Both ulnas were shorter, they were adequate to 19 gw while both radius were missing, with the characteristic position of both hands. Both thumbs had normal morphologies and positions. Other findings on fetus were neat. The patient was sent to Congenital Anomalies Consilium for further examinations and then to the Ethical Committee that approved the termination of the pregnancy at the request of the pregnant woman. Children born with this syndrome, due to the risk of bleeding in 40% of cases, die in their early childhood. Since this is about a severe anomaly, it is very important to detect this syndrome during the pregnancy as soon as possible. [ABSTRACT FROM AUTHOR]

Background/Aim. Preterm delivery together with insufficient body weight and death cases in newborns is the main issue in obstetrics. About 40% of preterm delivery is caused by infections. The aim of this study was to investigate whether and which bacterial infections of genital tract can be associated with preterm delivery, and depending on when diagnosis was made. Method. The study involved 216 pregnant women. According to pregnancy outcome, two groups were formed. The study group involved 29 pregnant women who had preterm delivery out of which nine were examined in I trimester, eight in II trimester and 12 in III trimester. The control group involved 187 pregnant women out of which 47 were examined in I trimester, 73 in II trimester and 67 in III trimester. Bacteriological examination of vaginal and cervical swabs was done in all pregnant women. Infection was diagnosed by finding bacterial antigen in cervical swabs or positive cultures of vaginal and/or cervical swabs followed by the presence of the increased number of polymorphonuclears in direct microscopic preparation. Results. The results showed that in III trimester of pregnancy vaginal bacterial infection was statistically more common (p = 0.021) in women who had preterm delivery (66.7%) in relation to women who delivered in term (29.9%). In this period of gestation the increased number of polymorphonuclears in DMP of vaginal swabs is more common in the women of the study group (75%) than in the women of the control group (43.3%). Preterm delivery was registered in 16.1% women whose microbiological analyses were done in I trimester, 9.9% women in whom microbiological analyses were done in II trimester and in 15.2% pregnant women microbiologically tested in III trimester. Conclusion. Based on the obtained results it could be concluded that bacterial infections of genital tract and period of gestation when infection is diagnosed have influence on reducing perinatal morbidity and mortality caused by preterm delivery. [ABSTRACT FROM AUTHOR]