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208 results on '"Crisafulli, Giovanni"'

1. DNA demethylation triggers cell free DNA release in colorectal cancer cells

Author

Pessei, Valeria, Macagno, Marco, Mariella, Elisa, Congiusta, Noemi, Battaglieri, Vittorio, Battuello, Paolo, Viviani, Marco, Gionfriddo, Giulia, Lamba, Simona, Lorenzato, Annalisa, Oddo, Daniele, Idrees, Fariha, Cavaliere, Alessandro, Bartolini, Alice, Guarrera, Simonetta, Linnebacher, Michael, Monteonofrio, Laura, Cardone, Luca, Milella, Michele, Bertotti, Andrea, Soddu, Silvia, Grassi, Elena, Crisafulli, Giovanni, Bardelli, Alberto, Barault, Ludovic, and Di Nicolantonio, Federica

Published
2024
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2. Post-surgery sequelae unrelated to disease progression and chemotherapy revealed in follow-up of patients with stage III colon cancer

Author

Mirandola, Alexia, Kudriavtsev, Andrei, Cofre Muñoz, Catalina Isabel, Navarro, Raquel Comas, Macagno, Marco, Daoud, Saidi, Sanchez, Cynthia, Pastor, Brice, Pisareva, Ekaterina, Marin, Mireia Sanchis, Ruiz, Javier Gonzalo, Piris, Alejandro, Rodriguez, Ariadna Garcia, Gonzalez, Nadia Saoudi, Vivancos, Ana, Quarà, Virginia, Mellano, Alfredo, Borghi, Felice, Corti, Giorgio, Marchiò, Caterina, Sapino, Anna, Bartolini, Alice, Crisafulli, Giovanni, Bardelli, Alberto, Di Maio, Massimo, Lossaint, Gerald, Frayssinoux, Florence, Crapez, Evelyne, Ychou, Marc, Soler, Ramon Salazar, Fenocchio, Elisabetta, Fernandez Calotti, Paula X., Mazard, Thibault, Vivas, Cristina Santos, Elez, Elena, Di Nicolantonio, Federica, and Thierry, Alain R.

Published
2024
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3. Concurrent RB1 and P53 pathway disruption predisposes to the development of a primitive neuronal component in high-grade gliomas depending on MYC-driven EBF3 transcription

Author

Pagani, Francesca, Orzan, Francesca, Lago, Sara, De Bacco, Francesca, Prelli, Marta, Cominelli, Manuela, Somenza, Elena, Gryzik, Magdalena, Balzarini, Piera, Ceresa, Davide, Marubbi, Daniela, Isella, Claudio, Crisafulli, Giovanni, Poli, Maura, Malatesta, Paolo, Galli, Rossella, Ronca, Roberto, Zippo, Alessio, Boccaccio, Carla, and Poliani, Pietro Luigi

Published
2025
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4. Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas

Author

De Bacco, Francesca, Orzan, Francesca, Crisafulli, Giovanni, Prelli, Marta, Isella, Claudio, Casanova, Elena, Albano, Raffaella, Reato, Gigliola, Erriquez, Jessica, D’Ambrosio, Antonio, Panero, Mara, Dall’Aglio, Carmine, Casorzo, Laura, Cominelli, Manuela, Pagani, Francesca, Melcarne, Antonio, Zeppa, Pietro, Altieri, Roberto, Morra, Isabella, Cassoni, Paola, Garbossa, Diego, Cassisa, Anna, Bartolini, Alice, Pellegatta, Serena, Comoglio, Paolo M., Finocchiaro, Gaetano, Poliani, Pietro L., and Boccaccio, Carla

Published
2023
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6. Circulating tumor DNA to guide rechallenge with panitumumab in metastatic colorectal cancer: the phase 2 CHRONOS trial

Author

Sartore-Bianchi, Andrea, Pietrantonio, Filippo, Lonardi, Sara, Mussolin, Benedetta, Rua, Francesco, Crisafulli, Giovanni, Bartolini, Alice, Fenocchio, Elisabetta, Amatu, Alessio, Manca, Paolo, Bergamo, Francesca, Tosi, Federica, Mauri, Gianluca, Ambrosini, Margherita, Daniel, Francesca, Torri, Valter, Vanzulli, Angelo, Regge, Daniele, Cappello, Giovanni, Marchiò, Caterina, Berrino, Enrico, Sapino, Anna, Marsoni, Silvia, Siena, Salvatore, and Bardelli, Alberto

Published
2022
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8. Liquid Biopsy and Challenge of Assay Heterogeneity for Minimal Residual Disease Assessment in Colon Cancer Treatment.

Author

Crisafulli, Giovanni

Subjects
*COLON cancer, *ADJUVANT chemotherapy, *COLORECTAL cancer, *SURVIVAL rate, *COLON diseases
Abstract

This review provides a comprehensive overview of the evolving role of minimal residual disease (MRD) for patients with Colon Cancer (CC). Currently, the standard of care for patients with non-metastatic CC is adjuvant chemotherapy (ACT) for all patients with stage III and high-risk stage II CC following surgical intervention. Despite a 5–20% improvement in long-term survival outcomes, this approach also results in a significant proportion of patients receiving ACT without any therapeutic benefit and being unnecessarily exposed to the risks of secondary side effects. This underscores an unmet clinical need for more precise stratification to distinguish patients who necessitate ACT from those who can be treated with surgery alone. By employing liquid biopsy, it is possible to discern MRD enabling the categorization of patients as MRD-positive or MRD-negative, potentially revolutionizing the management of ACT. This review aimed to examine the heterogeneity of methodologies currently available for MRD detection, encompassing the state-of-the-art technologies, their respective advantages, limitations, and the technological challenges and multi-omic approaches that can be utilized to enhance assay performance. Furthermore, a discussion was held regarding the clinical trials that employ an MRD assay focusing on the heterogeneity of the assays used. These differences in methodology, target selection, and performance risk producing inconsistent results that may not solely reflect biological/clinical differences but may be the consequence of the preferential use of particular products in studies conducted in different countries. Standardization and harmonization of MRD assays will be crucial to ensure the liquid revolution delivers reliable and clinically actionable outcomes for patients. [ABSTRACT FROM AUTHOR]

Published
2025
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10. Mutational Signatures in Colorectal Cancer: Translational Insights, Clinical Applications, and Limitations.

Author

Crisafulli, Giovanni

Subjects
*MEDICAL protocols, *MEDICAL quality control, *GENOMICS, *COLORECTAL cancer, *DNA, *DECISION making in clinical medicine, *CANCER chemotherapy, *GENES, *DNA damage, *GENETIC mutation, *MEDICAL practice
Abstract

Simple Summary: This review provides a comprehensive overview of the current knowledge on mutational signatures in colorectal cancer (CRC), highlighting their potential clinical applications. It discusses the challenges and limitations in translating these analyses into clinical practice and proposes strategies to overcome these obstacles. Additionally, it provides insights into future directions and emerging proof-of-concept studies that highlight the translational potential of mutational signature analysis in improving patient care and outcomes in CRC. A multitude of exogenous and endogenous processes have the potential to result in DNA damage. While the repair mechanisms are typically capable of correcting this damage, errors in the repair process can result in mutations. The findings of research conducted in 2012 indicate that mutations do not occur randomly but rather follow specific patterns that can be attributed to known or inferred mutational processes. The process of mutational signature analysis allows for the inference of the predominant mutational process for a given cancer sample, with significant potential for clinical applications. A deeper comprehension of these mutational signatures in CRC could facilitate enhanced prevention strategies, facilitate the comprehension of genotoxic drug activity, predict responses to personalized treatments, and, in the future, inform the development of targeted therapies in the context of precision oncology. The efforts of numerous researchers have led to the identification of several mutational signatures, which can be categorized into different mutational signature references. In CRC, distinct mutational signatures are identified as correlating with mismatch repair deficiency, polymerase mutations, and chemotherapy treatment. In this context, a mutational signature analysis offers considerable potential for enhancing minimal residual disease (MRD) tests in stage II (high-risk) and stage III CRC post-surgery, stratifying CRC based on the impacts of genetic and epigenetic alterations for precision oncology, identifying potential therapeutic vulnerabilities, and evaluating drug efficacy and guiding therapy, as illustrated in a proof-of-concept clinical trial. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Transcriptome‐wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer

Author

Mariella, Elisa, primary, Grasso, Gaia, additional, Miotto, Martina, additional, Buzo, Kristi, additional, Reilly, Nicole Megan, additional, Andrei, Pietro, additional, Vitiello, Pietro Paolo, additional, Crisafulli, Giovanni, additional, Arena, Sabrina, additional, Rospo, Giuseppe, additional, Corti, Giorgio, additional, Lorenzato, Annalisa, additional, Cancelliere, Carlotta, additional, Barault, Ludovic, additional, Gionfriddo, Giulia, additional, Linnebacher, Michael, additional, Russo, Mariangela, additional, Di Nicolantonio, Federica, additional, and Bardelli, Alberto, additional

Published
2024
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12. Adaptive mutability of colorectal cancers in response to targeted therapies

Author

Russo, Mariangela, Crisafulli, Giovanni, Sogari, Alberto, Reilly, Nicole M., Arena, Sabrina, Lamba, Simona, Bartolini, Alice, Amodio, Vito, Magrì, Alessandro, Novara, Luca, Sarotto, Ivana, Nagel, Zachary D., Piett, Cortt G., Amatu, Alessio, Sartore-Bianchi, Andrea, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Corigliano, Mattia, Gherardi, Marco, Lagomarsino, Marco Cosentino, Di Nicolantonio, Federica, and Bardelli, Alberto

Published
2019

13. A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology

Author

Corti, Giorgio, Bartolini, Alice, Crisafulli, Giovanni, Novara, Luca, Rospo, Giuseppe, Montone, Monica, Negrino, Carola, Mussolin, Benedetta, Buscarino, Michela, Isella, Claudio, Barault, Ludovic, Siravegna, Giulia, Siena, Salvatore, Marsoni, Silvia, Di Nicolantonio, Federica, Medico, Enzo, and Bardelli, Alberto

Published
2019
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15. Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer

Author

Siravegna, Giulia, Lazzari, Luca, Crisafulli, Giovanni, Sartore-Bianchi, Andrea, Mussolin, Benedetta, Cassingena, Andrea, Martino, Cosimo, Lanman, Richard B., Nagy, Rebecca J., Fairclough, Stephen, Rospo, Giuseppe, Corti, Giorgio, Bartolini, Alice, Arcella, Pamela, Montone, Monica, Lodi, Francesca, Lorenzato, Annalisa, Vanzati, Alice, Valtorta, Emanuele, Cappello, Giovanni, Bertotti, Andrea, Lonardi, Sara, Zagonel, Vittorina, Leone, Francesco, Russo, Mariangela, Balsamo, Antonella, Truini, Mauro, Di Nicolantonio, Federica, Amatu, Alessio, Bonazzina, Erica, Ghezzi, Silvia, Regge, Daniele, Vanzulli, Angelo, Trusolino, Livio, Siena, Salvatore, Marsoni, Silvia, and Bardelli, Alberto

Published
2018
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18. Abstract LB058: A transcriptome-wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer

Author

Grasso, Gaia, primary, Marriella, Elisa, additional, Miotto, Martina, additional, Buzo, Kristi, additional, Reilly, Nicole M., additional, Andrei, Pietro, additional, Vitiello, Pietro P., additional, Crisafulli, Giovanni, additional, Arena, Sabrina, additional, Rospo, Giuseppe, additional, Corti, Giorgio, additional, Lorenzato, Annalisa, additional, Cancelliere, Carlotta, additional, Barault, Ludovic, additional, Gionfriddo, Giulia, additional, Linnebacher, Michael, additional, Russo, Mariangela, additional, Nicolantonio, Federica Di, additional, and Bardelli, Alberto, additional

Published
2023
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19. Data from Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients

Author

Crisafulli, Giovanni, primary, Sartore-Bianchi, Andrea, primary, Lazzari, Luca, primary, Pietrantonio, Filippo, primary, Amatu, Alessio, primary, Macagno, Marco, primary, Barault, Ludovic, primary, Cassingena, Andrea, primary, Bartolini, Alice, primary, Luraghi, Paolo, primary, Mauri, Gianluca, primary, Battuello, Paolo, primary, Personeni, Nicola, primary, Zampino, Maria Giulia, primary, Pessei, Valeria, primary, Vitiello, Pietro Paolo, primary, Tosi, Federica, primary, Idotta, Laura, primary, Morano, Federica, primary, Valtorta, Emanuele, primary, Bonoldi, Emanuela, primary, Germano, Giovanni, primary, Di Nicolantonio, Federica, primary, Marsoni, Silvia, primary, Siena, Salvatore, primary, and Bardelli, Alberto, primary

Published
2023
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21. Supplementary Figure from Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients

Author

Crisafulli, Giovanni, primary, Sartore-Bianchi, Andrea, primary, Lazzari, Luca, primary, Pietrantonio, Filippo, primary, Amatu, Alessio, primary, Macagno, Marco, primary, Barault, Ludovic, primary, Cassingena, Andrea, primary, Bartolini, Alice, primary, Luraghi, Paolo, primary, Mauri, Gianluca, primary, Battuello, Paolo, primary, Personeni, Nicola, primary, Zampino, Maria Giulia, primary, Pessei, Valeria, primary, Vitiello, Pietro Paolo, primary, Tosi, Federica, primary, Idotta, Laura, primary, Morano, Federica, primary, Valtorta, Emanuele, primary, Bonoldi, Emanuela, primary, Germano, Giovanni, primary, Di Nicolantonio, Federica, primary, Marsoni, Silvia, primary, Siena, Salvatore, primary, and Bardelli, Alberto, primary

Published
2023
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22. Supplementary Data 2 from Liquid Biopsy of Cerebrospinal Fluid Enables Selective Profiling of Glioma Molecular Subtypes at First Clinical Presentation

Author

Orzan, Francesca, primary, De Bacco, Francesca, primary, Lazzarini, Elisabetta, primary, Crisafulli, Giovanni, primary, Gasparini, Alessandra, primary, Dipasquale, Angelo, primary, Barault, Ludovic, primary, Macagno, Marco, primary, Persico, Pasquale, primary, Pessina, Federico, primary, Bono, Beatrice, primary, Giordano, Laura, primary, Zeppa, Pietro, primary, Melcarne, Antonio, primary, Cassoni, Paola, primary, Garbossa, Diego, primary, Santoro, Armando, primary, Comoglio, Paolo M., primary, Indraccolo, Stefano, primary, Simonelli, Matteo, primary, and Boccaccio, Carla, primary

Published
2023
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23. Data from Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy

Author

Picco, Gabriele, primary, Cattaneo, Chiara M., primary, van Vliet, Esmée J., primary, Crisafulli, Giovanni, primary, Rospo, Giuseppe, primary, Consonni, Sarah, primary, Vieira, Sara F., primary, Rodríguez, Iñigo Sánchez, primary, Cancelliere, Carlotta, primary, Banerjee, Ruby, primary, Schipper, Luuk J., primary, Oddo, Daniele, primary, Dijkstra, Krijn K., primary, Cinatl, Jindrich, primary, Michaelis, Martin, primary, Yang, Fengtang, primary, Di Nicolantonio, Federica, primary, Sartore-Bianchi, Andrea, primary, Siena, Salvatore, primary, Arena, Sabrina, primary, Voest, Emile E., primary, Bardelli, Alberto, primary, and Garnett, Mathew J., primary

Published
2023
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24. Supplementary Figure 4 from Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy

Author

Picco, Gabriele, primary, Cattaneo, Chiara M., primary, van Vliet, Esmée J., primary, Crisafulli, Giovanni, primary, Rospo, Giuseppe, primary, Consonni, Sarah, primary, Vieira, Sara F., primary, Rodríguez, Iñigo Sánchez, primary, Cancelliere, Carlotta, primary, Banerjee, Ruby, primary, Schipper, Luuk J., primary, Oddo, Daniele, primary, Dijkstra, Krijn K., primary, Cinatl, Jindrich, primary, Michaelis, Martin, primary, Yang, Fengtang, primary, Di Nicolantonio, Federica, primary, Sartore-Bianchi, Andrea, primary, Siena, Salvatore, primary, Arena, Sabrina, primary, Voest, Emile E., primary, Bardelli, Alberto, primary, and Garnett, Mathew J., primary

Published
2023
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25. Supplementary Figure 5 from Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy

Author

Picco, Gabriele, primary, Cattaneo, Chiara M., primary, van Vliet, Esmée J., primary, Crisafulli, Giovanni, primary, Rospo, Giuseppe, primary, Consonni, Sarah, primary, Vieira, Sara F., primary, Rodríguez, Iñigo Sánchez, primary, Cancelliere, Carlotta, primary, Banerjee, Ruby, primary, Schipper, Luuk J., primary, Oddo, Daniele, primary, Dijkstra, Krijn K., primary, Cinatl, Jindrich, primary, Michaelis, Martin, primary, Yang, Fengtang, primary, Di Nicolantonio, Federica, primary, Sartore-Bianchi, Andrea, primary, Siena, Salvatore, primary, Arena, Sabrina, primary, Voest, Emile E., primary, Bardelli, Alberto, primary, and Garnett, Mathew J., primary

Published
2023
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26. Data from Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer

Author

Russo, Mariangela, primary, Misale, Sandra, primary, Wei, Ge, primary, Siravegna, Giulia, primary, Crisafulli, Giovanni, primary, Lazzari, Luca, primary, Corti, Giorgio, primary, Rospo, Giuseppe, primary, Novara, Luca, primary, Mussolin, Benedetta, primary, Bartolini, Alice, primary, Cam, Nicholas, primary, Patel, Roopal, primary, Yan, Shunqi, primary, Shoemaker, Robert, primary, Wild, Robert, primary, Di Nicolantonio, Federica, primary, Bianchi, Andrea Sartore, primary, Li, Gang, primary, Siena, Salvatore, primary, and Bardelli, Alberto, primary

Published
2023
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27. Data from Liquid Biopsy of Cerebrospinal Fluid Enables Selective Profiling of Glioma Molecular Subtypes at First Clinical Presentation

Author

Orzan, Francesca, primary, De Bacco, Francesca, primary, Lazzarini, Elisabetta, primary, Crisafulli, Giovanni, primary, Gasparini, Alessandra, primary, Dipasquale, Angelo, primary, Barault, Ludovic, primary, Macagno, Marco, primary, Persico, Pasquale, primary, Pessina, Federico, primary, Bono, Beatrice, primary, Giordano, Laura, primary, Zeppa, Pietro, primary, Melcarne, Antonio, primary, Cassoni, Paola, primary, Garbossa, Diego, primary, Santoro, Armando, primary, Comoglio, Paolo M., primary, Indraccolo, Stefano, primary, Simonelli, Matteo, primary, and Boccaccio, Carla, primary

Published
2023
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28. Supplementary Figure 1 from Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy

Author

Picco, Gabriele, primary, Cattaneo, Chiara M., primary, van Vliet, Esmée J., primary, Crisafulli, Giovanni, primary, Rospo, Giuseppe, primary, Consonni, Sarah, primary, Vieira, Sara F., primary, Rodríguez, Iñigo Sánchez, primary, Cancelliere, Carlotta, primary, Banerjee, Ruby, primary, Schipper, Luuk J., primary, Oddo, Daniele, primary, Dijkstra, Krijn K., primary, Cinatl, Jindrich, primary, Michaelis, Martin, primary, Yang, Fengtang, primary, Di Nicolantonio, Federica, primary, Sartore-Bianchi, Andrea, primary, Siena, Salvatore, primary, Arena, Sabrina, primary, Voest, Emile E., primary, Bardelli, Alberto, primary, and Garnett, Mathew J., primary

Published
2023
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29. Supplementary Table 1 from Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy

Author

Picco, Gabriele, primary, Cattaneo, Chiara M., primary, van Vliet, Esmée J., primary, Crisafulli, Giovanni, primary, Rospo, Giuseppe, primary, Consonni, Sarah, primary, Vieira, Sara F., primary, Rodríguez, Iñigo Sánchez, primary, Cancelliere, Carlotta, primary, Banerjee, Ruby, primary, Schipper, Luuk J., primary, Oddo, Daniele, primary, Dijkstra, Krijn K., primary, Cinatl, Jindrich, primary, Michaelis, Martin, primary, Yang, Fengtang, primary, Di Nicolantonio, Federica, primary, Sartore-Bianchi, Andrea, primary, Siena, Salvatore, primary, Arena, Sabrina, primary, Voest, Emile E., primary, Bardelli, Alberto, primary, and Garnett, Mathew J., primary

Published
2023
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30. Supplementary Figure 3 from Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy

Author

Picco, Gabriele, primary, Cattaneo, Chiara M., primary, van Vliet, Esmée J., primary, Crisafulli, Giovanni, primary, Rospo, Giuseppe, primary, Consonni, Sarah, primary, Vieira, Sara F., primary, Rodríguez, Iñigo Sánchez, primary, Cancelliere, Carlotta, primary, Banerjee, Ruby, primary, Schipper, Luuk J., primary, Oddo, Daniele, primary, Dijkstra, Krijn K., primary, Cinatl, Jindrich, primary, Michaelis, Martin, primary, Yang, Fengtang, primary, Di Nicolantonio, Federica, primary, Sartore-Bianchi, Andrea, primary, Siena, Salvatore, primary, Arena, Sabrina, primary, Voest, Emile E., primary, Bardelli, Alberto, primary, and Garnett, Mathew J., primary

Published
2023
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31. Supplementary Methods, Figure Legends, Table Legends, Figures S1 - S4, Tables S1 - S5 from Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer

Author

Russo, Mariangela, primary, Misale, Sandra, primary, Wei, Ge, primary, Siravegna, Giulia, primary, Crisafulli, Giovanni, primary, Lazzari, Luca, primary, Corti, Giorgio, primary, Rospo, Giuseppe, primary, Novara, Luca, primary, Mussolin, Benedetta, primary, Bartolini, Alice, primary, Cam, Nicholas, primary, Patel, Roopal, primary, Yan, Shunqi, primary, Shoemaker, Robert, primary, Wild, Robert, primary, Di Nicolantonio, Federica, primary, Bianchi, Andrea Sartore, primary, Li, Gang, primary, Siena, Salvatore, primary, and Bardelli, Alberto, primary

Published
2023
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32. Data from Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer

Author

Russo, Mariangela, primary, Siravegna, Giulia, primary, Blaszkowsky, Lawrence S., primary, Corti, Giorgio, primary, Crisafulli, Giovanni, primary, Ahronian, Leanne G., primary, Mussolin, Benedetta, primary, Kwak, Eunice L., primary, Buscarino, Michela, primary, Lazzari, Luca, primary, Valtorta, Emanuele, primary, Truini, Mauro, primary, Jessop, Nicholas A., primary, Robinson, Hayley E., primary, Hong, Theodore S., primary, Mino-Kenudson, Mari, primary, Di Nicolantonio, Federica, primary, Thabet, Ashraf, primary, Sartore-Bianchi, Andrea, primary, Siena, Salvatore, primary, Iafrate, A. John, primary, Bardelli, Alberto, primary, and Corcoran, Ryan B., primary

Published
2023
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33. Supplementary Information 1 from Liquid Biopsy of Cerebrospinal Fluid Enables Selective Profiling of Glioma Molecular Subtypes at First Clinical Presentation

Author

Orzan, Francesca, primary, De Bacco, Francesca, primary, Lazzarini, Elisabetta, primary, Crisafulli, Giovanni, primary, Gasparini, Alessandra, primary, Dipasquale, Angelo, primary, Barault, Ludovic, primary, Macagno, Marco, primary, Persico, Pasquale, primary, Pessina, Federico, primary, Bono, Beatrice, primary, Giordano, Laura, primary, Zeppa, Pietro, primary, Melcarne, Antonio, primary, Cassoni, Paola, primary, Garbossa, Diego, primary, Santoro, Armando, primary, Comoglio, Paolo M., primary, Indraccolo, Stefano, primary, Simonelli, Matteo, primary, and Boccaccio, Carla, primary

Published
2023
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34. Supplementary Data 3 from Liquid Biopsy of Cerebrospinal Fluid Enables Selective Profiling of Glioma Molecular Subtypes at First Clinical Presentation

Author

Orzan, Francesca, primary, De Bacco, Francesca, primary, Lazzarini, Elisabetta, primary, Crisafulli, Giovanni, primary, Gasparini, Alessandra, primary, Dipasquale, Angelo, primary, Barault, Ludovic, primary, Macagno, Marco, primary, Persico, Pasquale, primary, Pessina, Federico, primary, Bono, Beatrice, primary, Giordano, Laura, primary, Zeppa, Pietro, primary, Melcarne, Antonio, primary, Cassoni, Paola, primary, Garbossa, Diego, primary, Santoro, Armando, primary, Comoglio, Paolo M., primary, Indraccolo, Stefano, primary, Simonelli, Matteo, primary, and Boccaccio, Carla, primary

Published
2023
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35. Supplementary Figures S1 - S3, Tables S1 - S6 from Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer

Author

Russo, Mariangela, primary, Siravegna, Giulia, primary, Blaszkowsky, Lawrence S., primary, Corti, Giorgio, primary, Crisafulli, Giovanni, primary, Ahronian, Leanne G., primary, Mussolin, Benedetta, primary, Kwak, Eunice L., primary, Buscarino, Michela, primary, Lazzari, Luca, primary, Valtorta, Emanuele, primary, Truini, Mauro, primary, Jessop, Nicholas A., primary, Robinson, Hayley E., primary, Hong, Theodore S., primary, Mino-Kenudson, Mari, primary, Di Nicolantonio, Federica, primary, Thabet, Ashraf, primary, Sartore-Bianchi, Andrea, primary, Siena, Salvatore, primary, Iafrate, A. John, primary, Bardelli, Alberto, primary, and Corcoran, Ryan B., primary

Published
2023
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36. Supplementary Figure 2 from Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy

Author

Picco, Gabriele, primary, Cattaneo, Chiara M., primary, van Vliet, Esmée J., primary, Crisafulli, Giovanni, primary, Rospo, Giuseppe, primary, Consonni, Sarah, primary, Vieira, Sara F., primary, Rodríguez, Iñigo Sánchez, primary, Cancelliere, Carlotta, primary, Banerjee, Ruby, primary, Schipper, Luuk J., primary, Oddo, Daniele, primary, Dijkstra, Krijn K., primary, Cinatl, Jindrich, primary, Michaelis, Martin, primary, Yang, Fengtang, primary, Di Nicolantonio, Federica, primary, Sartore-Bianchi, Andrea, primary, Siena, Salvatore, primary, Arena, Sabrina, primary, Voest, Emile E., primary, Bardelli, Alberto, primary, and Garnett, Mathew J., primary

Published
2023
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37. Cell Model Network-UK from Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair–Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy

Author

Picco, Gabriele, primary, Cattaneo, Chiara M., primary, van Vliet, Esmée J., primary, Crisafulli, Giovanni, primary, Rospo, Giuseppe, primary, Consonni, Sarah, primary, Vieira, Sara F., primary, Rodríguez, Iñigo Sánchez, primary, Cancelliere, Carlotta, primary, Banerjee, Ruby, primary, Schipper, Luuk J., primary, Oddo, Daniele, primary, Dijkstra, Krijn K., primary, Cinatl, Jindrich, primary, Michaelis, Martin, primary, Yang, Fengtang, primary, Di Nicolantonio, Federica, primary, Sartore-Bianchi, Andrea, primary, Siena, Salvatore, primary, Arena, Sabrina, primary, Voest, Emile E., primary, Bardelli, Alberto, primary, and Garnett, Mathew J., primary

Published
2023
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38. Supplementary Data 1 from Liquid Biopsy of Cerebrospinal Fluid Enables Selective Profiling of Glioma Molecular Subtypes at First Clinical Presentation

Author

Orzan, Francesca, primary, De Bacco, Francesca, primary, Lazzarini, Elisabetta, primary, Crisafulli, Giovanni, primary, Gasparini, Alessandra, primary, Dipasquale, Angelo, primary, Barault, Ludovic, primary, Macagno, Marco, primary, Persico, Pasquale, primary, Pessina, Federico, primary, Bono, Beatrice, primary, Giordano, Laura, primary, Zeppa, Pietro, primary, Melcarne, Antonio, primary, Cassoni, Paola, primary, Garbossa, Diego, primary, Santoro, Armando, primary, Comoglio, Paolo M., primary, Indraccolo, Stefano, primary, Simonelli, Matteo, primary, and Boccaccio, Carla, primary

Published
2023
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39. Supplementary Figure S3 from Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer

Author

Arena, Sabrina, primary, Bellosillo, Beatriz, primary, Siravegna, Giulia, primary, Martínez, Alejandro, primary, Cañadas, Israel, primary, Lazzari, Luca, primary, Ferruz, Noelia, primary, Russo, Mariangela, primary, Misale, Sandra, primary, González, Iria, primary, Iglesias, Mar, primary, Gavilan, Elena, primary, Corti, Giorgio, primary, Hobor, Sebastijan, primary, Crisafulli, Giovanni, primary, Salido, Marta, primary, Sánchez, Juan, primary, Dalmases, Alba, primary, Bellmunt, Joaquim, primary, De Fabritiis, Gianni, primary, Rovira, Ana, primary, Di Nicolantonio, Federica, primary, Albanell, Joan, primary, Bardelli, Alberto, primary, and Montagut, Clara, primary

Published
2023
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40. Supplementary Figure Legends from Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer

Author

Oddo, Daniele, primary, Sennott, Erin M., primary, Barault, Ludovic, primary, Valtorta, Emanuele, primary, Arena, Sabrina, primary, Cassingena, Andrea, primary, Filiciotto, Genny, primary, Marzolla, Giulia, primary, Elez, Elena, primary, van Geel, Robin M.J.M., primary, Bartolini, Alice, primary, Crisafulli, Giovanni, primary, Boscaro, Valentina, primary, Godfrey, Jason T., primary, Buscarino, Michela, primary, Cancelliere, Carlotta, primary, Linnebacher, Michael, primary, Corti, Giorgio, primary, Truini, Mauro, primary, Siravegna, Giulia, primary, Grasselli, Julieta, primary, Gallicchio, Margherita, primary, Bernards, René, primary, Schellens, Jan H.M., primary, Tabernero, Josep, primary, Engelman, Jeffrey A., primary, Sartore-Bianchi, Andrea, primary, Bardelli, Alberto, primary, Siena, Salvatore, primary, Corcoran, Ryan B., primary, and Di Nicolantonio, Federica, primary

Published
2023
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41. Supplementary Materials and Methods from Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer

Author

Oddo, Daniele, primary, Sennott, Erin M., primary, Barault, Ludovic, primary, Valtorta, Emanuele, primary, Arena, Sabrina, primary, Cassingena, Andrea, primary, Filiciotto, Genny, primary, Marzolla, Giulia, primary, Elez, Elena, primary, van Geel, Robin M.J.M., primary, Bartolini, Alice, primary, Crisafulli, Giovanni, primary, Boscaro, Valentina, primary, Godfrey, Jason T., primary, Buscarino, Michela, primary, Cancelliere, Carlotta, primary, Linnebacher, Michael, primary, Corti, Giorgio, primary, Truini, Mauro, primary, Siravegna, Giulia, primary, Grasselli, Julieta, primary, Gallicchio, Margherita, primary, Bernards, René, primary, Schellens, Jan H.M., primary, Tabernero, Josep, primary, Engelman, Jeffrey A., primary, Sartore-Bianchi, Andrea, primary, Bardelli, Alberto, primary, Siena, Salvatore, primary, Corcoran, Ryan B., primary, and Di Nicolantonio, Federica, primary

Published
2023
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42. Data from Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer

Author

Oddo, Daniele, primary, Sennott, Erin M., primary, Barault, Ludovic, primary, Valtorta, Emanuele, primary, Arena, Sabrina, primary, Cassingena, Andrea, primary, Filiciotto, Genny, primary, Marzolla, Giulia, primary, Elez, Elena, primary, van Geel, Robin M.J.M., primary, Bartolini, Alice, primary, Crisafulli, Giovanni, primary, Boscaro, Valentina, primary, Godfrey, Jason T., primary, Buscarino, Michela, primary, Cancelliere, Carlotta, primary, Linnebacher, Michael, primary, Corti, Giorgio, primary, Truini, Mauro, primary, Siravegna, Giulia, primary, Grasselli, Julieta, primary, Gallicchio, Margherita, primary, Bernards, René, primary, Schellens, Jan H.M., primary, Tabernero, Josep, primary, Engelman, Jeffrey A., primary, Sartore-Bianchi, Andrea, primary, Bardelli, Alberto, primary, Siena, Salvatore, primary, Corcoran, Ryan B., primary, and Di Nicolantonio, Federica, primary

Published
2023
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43. Supplementary Figures and Tables from Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer

Author

Oddo, Daniele, primary, Sennott, Erin M., primary, Barault, Ludovic, primary, Valtorta, Emanuele, primary, Arena, Sabrina, primary, Cassingena, Andrea, primary, Filiciotto, Genny, primary, Marzolla, Giulia, primary, Elez, Elena, primary, van Geel, Robin M.J.M., primary, Bartolini, Alice, primary, Crisafulli, Giovanni, primary, Boscaro, Valentina, primary, Godfrey, Jason T., primary, Buscarino, Michela, primary, Cancelliere, Carlotta, primary, Linnebacher, Michael, primary, Corti, Giorgio, primary, Truini, Mauro, primary, Siravegna, Giulia, primary, Grasselli, Julieta, primary, Gallicchio, Margherita, primary, Bernards, René, primary, Schellens, Jan H.M., primary, Tabernero, Josep, primary, Engelman, Jeffrey A., primary, Sartore-Bianchi, Andrea, primary, Bardelli, Alberto, primary, Siena, Salvatore, primary, Corcoran, Ryan B., primary, and Di Nicolantonio, Federica, primary

Published
2023
Full Text
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44. Supplementary Table S3 from Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer

Author

Arena, Sabrina, primary, Bellosillo, Beatriz, primary, Siravegna, Giulia, primary, Martínez, Alejandro, primary, Cañadas, Israel, primary, Lazzari, Luca, primary, Ferruz, Noelia, primary, Russo, Mariangela, primary, Misale, Sandra, primary, González, Iria, primary, Iglesias, Mar, primary, Gavilan, Elena, primary, Corti, Giorgio, primary, Hobor, Sebastijan, primary, Crisafulli, Giovanni, primary, Salido, Marta, primary, Sánchez, Juan, primary, Dalmases, Alba, primary, Bellmunt, Joaquim, primary, De Fabritiis, Gianni, primary, Rovira, Ana, primary, Di Nicolantonio, Federica, primary, Albanell, Joan, primary, Bardelli, Alberto, primary, and Montagut, Clara, primary

Published
2023
Full Text
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45. Supplementary Table and Figure Legends from Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer

Author

Arena, Sabrina, primary, Bellosillo, Beatriz, primary, Siravegna, Giulia, primary, Martínez, Alejandro, primary, Cañadas, Israel, primary, Lazzari, Luca, primary, Ferruz, Noelia, primary, Russo, Mariangela, primary, Misale, Sandra, primary, González, Iria, primary, Iglesias, Mar, primary, Gavilan, Elena, primary, Corti, Giorgio, primary, Hobor, Sebastijan, primary, Crisafulli, Giovanni, primary, Salido, Marta, primary, Sánchez, Juan, primary, Dalmases, Alba, primary, Bellmunt, Joaquim, primary, De Fabritiis, Gianni, primary, Rovira, Ana, primary, Di Nicolantonio, Federica, primary, Albanell, Joan, primary, Bardelli, Alberto, primary, and Montagut, Clara, primary

Published
2023
Full Text
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46. Liquid Biopsy of Cerebrospinal Fluid Enables Selective Profiling of Glioma Molecular Subtypes at First Clinical Presentation

Author

Orzan, Francesca, primary, De Bacco, Francesca, additional, Lazzarini, Elisabetta, additional, Crisafulli, Giovanni, additional, Gasparini, Alessandra, additional, Dipasquale, Angelo, additional, Barault, Ludovic, additional, Macagno, Marco, additional, Persico, Pasquale, additional, Pessina, Federico, additional, Bono, Beatrice, additional, Giordano, Laura, additional, Zeppa, Pietro, additional, Melcarne, Antonio, additional, Cassoni, Paola, additional, Garbossa, Diego, additional, Santoro, Armando, additional, Comoglio, Paolo M., additional, Indraccolo, Stefano, additional, Simonelli, Matteo, additional, and Boccaccio, Carla, additional

Published
2023
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47. Case report: Preclinical efficacy of NEDD8 and proteasome inhibitors in patient-derived models of signet ring high-grade mucinous colorectal cancer from a Lynch syndrome patient

Author

Torchiaro, Erica, primary, Petti, Consalvo, additional, Arena, Sabrina, additional, Sassi, Francesco, additional, Migliardi, Giorgia, additional, Mellano, Alfredo, additional, Porporato, Roberta, additional, Basiricò, Marco, additional, Gammaitoni, Loretta, additional, Berrino, Enrico, additional, Montone, Monica, additional, Corti, Giorgio, additional, Crisafulli, Giovanni, additional, Marchiò, Caterina, additional, Bardelli, Alberto, additional, and Medico, Enzo, additional

Published
2023
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49. DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination

Author

Merlini, Alessandra, primary, Centomo, Maria Laura, additional, Ferrero, Giulio, additional, Chiabotto, Giulia, additional, Miglio, Umberto, additional, Berrino, Enrico, additional, Giordano, Giorgia, additional, Brusco, Silvia, additional, Pisacane, Alberto, additional, Maldi, Elena, additional, Sarotto, Ivana, additional, Capozzi, Federica, additional, Lano, Cristina, additional, Isella, Claudio, additional, Crisafulli, Giovanni, additional, Aglietta, Massimo, additional, Dei Tos, Angelo Paolo, additional, Sbaraglia, Marta, additional, Sangiolo, Dario, additional, D’Ambrosio, Lorenzo, additional, Bardelli, Alberto, additional, Pignochino, Ymera, additional, and Grignani, Giovanni, additional

Published
2022
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