Search

Your search keyword '"Crespo Escobar, Paula"' showing total 34 results
Start Over Author "Crespo Escobar, Paula"
34 results on '"Crespo Escobar, Paula"'

8. Knowledge Gaps in Gluten-Free Diet Awareness among Patients and Healthcare Professionals: A Call for Enhanced Nutritional Education.

Author

Crespo-Escobar, Paula, Vázquez-Polo, Maialen, van der Hofstadt, Maria, Nuñez, Concepción, Montoro-Huguet, Miguel A., Churruca, Itziar, and Simón, Edurne

Abstract

Diet is the only treatment for celiac disease (CeD), and good adherence to a gluten-free diet (GFD) is the only way to ensure complete remission and to prevent complications. Limited education about the disease and a GFD is an attributing factor to inadequate adherence. Thus, our aim was to assess the current knowledge about a GFD and the clinical monitoring of adherence to the diet among CeD people and HCPs. Specific questionnaires were designed and distributed to assess the knowledge of CeD people (Q1 questionnaire) (n = 2437) and to analyze the follow-up of the disease from the perspective of patients (Q2 questionnaire) (n = 1294) and HCPs (Q3 questionnaire) (n = 346). Two-thirds of HCPs specialized in pediatric care, while one-third did so in adult care. In CeD people, general questions regarding food classification and cross-contamination are well understood. When patients have doubts, 51.4% reported using the Internet and social networks. Thus, it is crucial that resources like social media are reliable and provide valuable information. Q3 revealed the lack of time to follow up the diet after diagnosis (48% of HCPs allocate < 15 min), the interest in further training, and the need for a professional specialized in diets within the healthcare system. In conclusion, it is essential to enhance nutritional education to increase awareness of a GFD. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

9. Differences in the macronutrient and dietary fibre profile of gluten-free products as compared to their gluten-containing counterparts

Author

Calvo-Lerma, Joaquim, Crespo-Escobar, Paula, Martínez-Barona, Sandra, Fornés-Ferrer, Victoria, Donat, Ester, and Ribes-Koninckx, Carmen

Subjects
Care and treatment, Health aspects, Dietary fiber -- Health aspects, Celiac disease -- Care and treatment, Gluten-free diet -- Health aspects, Fiber in human nutrition -- Health aspects
Abstract

Author(s): Joaquim Calvo-Lerma [sup.1] [sup.2] , Paula Crespo-Escobar [sup.1] , Sandra Martínez-Barona [sup.1] , Victoria Fornés-Ferrer [sup.1] , Ester Donat [sup.3] , Carmen Ribes-Koninckx [sup.1] [sup.3] Author Affiliations: (1) Instituto [...], Background/Objectives Gluten-free diet is the lifelong therapy for patients with coeliac disease. A wide range of gluten-free products (GFP) is available, which mimics the characteristics of their gluten-containing counterparts (GCC). The aim of this study was to compare the macronutrient and dietary fibre composition of GFP and GCC currently available in Spain. Subjects/Methods A cross-sectional study analysing the nutritional differences between 621 GFP and 600 GCC based on labelling information was conducted. Food items were categorized in one of 14 food groups. The first six ingredients were noted for each food item. A linear regression model was used to explain differences in nutritional composition between GFP and GCC and three independent models were created for bread, pasta and biscuits. Results Results showed that GCC had higher protein content than GFP, especially in flour, bread, pasta and pizza. Bread had higher total and saturated fat contents in the GFP in which palm oil was the main fat used. Flours and starchy ingredients used in GFP formulation were mainly rice and corn flours and corn starch, and palm oil was the most commonly used fat. Conclusions In conclusion, GFP cannot currently be considered as equivalent substitutes for their GCC. The reformulation of the GFP with more healthy ingredients and ingredients is encouraged, using a healthy oil, pseudocereals and whole flour.

Published
2019
Full Text
View/download PDF

11. The role of gluten consumption at an early age in celiac disease development: a further analysis of the prospective PreventCD cohort study

Author

Crespo-Escobar, Paula, Mearin, Maria Luisa, Hervás, David, Auricchio, Renata, Castillejo, Gemma, Gyimesi, Judit, Martinez-Ojinaga, Eva, Werkstetter, Katharina, Vriezinga, Sabine Lisa, Korponay-Szabo, Ilma Rita, Polanco, Isabel, Troncone, Riccardo, Stoopman, Els, Kolaček, Sanja, Shamir, Raanan, Szajewska, Hania, Koletzko, Sibylle, and Ribes-Koninckx, Carmen

Published
2017
Full Text
View/download PDF

16. The Gluten-Free Diet for Celiac Disease: Critical Insights to Better Understand Clinical Outcomes

Author

Farmacia y ciencias de los alimentos, Farmazia eta elikagaien zientziak, Simón Magro, Edurne, Molero-Luis, Marta, Fueyo-Díaz, Ricardo, Costas-Batlle, Cristian, Crespo-Escobar, Paula, Montoro-Huguet, Miguel A., Farmacia y ciencias de los alimentos, Farmazia eta elikagaien zientziak, Simón Magro, Edurne, Molero-Luis, Marta, Fueyo-Díaz, Ricardo, Costas-Batlle, Cristian, Crespo-Escobar, Paula, and Montoro-Huguet, Miguel A.

Abstract

The gluten-free diet (GFD) remains a complex paradigm in managing celiac disease (CeD) in children and adults, and there are many reasons why GFD adherence should be strict to improve outcomes. However, this is a challenging task for patients, since they need to have access to quality healthcare resources that facilitate optimal GFD adherence. Understanding the strengths and weaknesses of the GFD, tackling coexisting nutritional deficiencies, and dealing with complex situations, such as seronegative CeD or non-responsive CeD, all require the involvement of a multidisciplinary team. The short- and long-term follow-up of CeD patients should preferably be performed by a combined Gastroenterology and Nutrition service with well-defined quality standards and the multidisciplinary involvement of physicians, nurses, dietitians, and psychologists. Nutritional advice and counseling by an experienced dietitian can reduce the costs associated with long-term follow-up of CeD patients. Likewise, psychological interventions may be essential in specific scenarios where implementing and sustaining a lifelong GFD can cause a significant psychological burden for patients. This manuscript aims to provide guidelines to improve clinical practice in the follow-up and monitoring of CeD patients and provide information on the nutritional risks of an ill-advised GFD. Clinicians, biochemists, food technologists, dietitians, and psychologists with a global view of the disease have been involved in its writing.

Published
2023

17. Ethical considerations within the ESPGHAN community

Author

Crespo-Escobar, Paula, Tapsas, Dimitros, Roggero, Paola, Sokal, Etienne, Yahav, Jacob, UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, and UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique

Subjects
Pediatrics, Perinatology and Child Health, Gastroenterology, Perinatology and Child Health, Pediatrics
Abstract

There are limited data on ethical issues related to the daily practice of members of the European Society for Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN). The role of the ESPGHAN Ethics Committee (EC) is to provide advice on such matters to its members. The present survey aimed to evaluate the current function, and reasons that ESPGHAN members consulted the ECs. One hundred and five participants from 24 different countries answered the questionnaire. Thirty-five point seven percent of the participants used the ESGHAN EC to ask about clinical practice problems and patient-related issues whereas 21.4% ask about human research questions. An important additional finding was that 66.3% of respondents consulted their hospital's EC when they had ethical concerns and 17.4% consulted with other colleagues with expertise. This is the first survey in the ESPGHAN and Europe that analyses ethical issues that are important to members of the National Societies for Pediatric Gastroenterology Hepatology and Nutrition.

Published
2022

18. Ethical considerations within the ESPGHAN community

Author

UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique, Crespo-Escobar, Paula, Tapsas, Dimitris, Roggero, Paola, Sokal, Etienne, Yahav, Jacob, UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique, Crespo-Escobar, Paula, Tapsas, Dimitris, Roggero, Paola, Sokal, Etienne, and Yahav, Jacob

Abstract

There are limited data on ethical issues related to the daily practice of members of the European Society for Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN). The role of the ESPGHAN Ethics Committee is to provide advice on such matters to its members. The present survey aimed to evaluate the current function, and reasons that ESPGHAN members consulted the Ethics Committees. 105 participants from 24 different countries answered the questionnaire. 35,7% of the participants used the ESGHAN Ethics Committee to ask about clinical practice problems and patients-related issues whereas 21,4% asking about human research questions. An important additional finding was that 66,3% of respondents consulted their Hospital's Ethics Committee when they had ethical concerns and 17,4% consulted with other colleagues with expertise. This is the first survey in the ESPGHAN and Europe that analyses ethical issues that are important to members of the National Societies for Pediatric Gastroenterology Hepatology and Nutrition.

Published
2022

19. Randomized Feeding Intervention in Infants at High Risk for Celiac Disease

Author

Vriezinga, Sabine L., Auricchio, Renata, Bravi, E., Castillejo, Gemma, Chmielewska, Anna, Crespo Escobar, Paula, Kolaček, Sanja, Koletzko, Sibylle, Korponay-Szabo, Ilma R., Mummert, Eckart, Polanco, Isabel, Putter, Hein, Ribes-Koninckx, Carmen, Shamir, Raanan, Szajewska, Hania, Werkstetter, Katharina, Greco, Luigi, Gyimesi, Judit, Hartman, Corina, Hogen Esch, Caroline, Hopman, Erica, Ivarsson, Anneli, Koltai, Tunde, Koning, Frits, Martinez-Ojinaga, Eva, te Marvelde, Chantal, Pavic, Ana, Romanos, Jihane, Stoopman, Els, Villanacci, Vincenzo, Wijmenga, Cisca, Troncone, Ricardo, and Mearin, M. Luisa

Published
2014
Full Text
View/download PDF

21. Growth rate of coeliac children is compromised before the onset of the disease

Author

Auricchio, Renata, primary, Stellato, Pio, additional, Bruzzese, Dario, additional, Cielo, Donatella, additional, Chiurazzi, Alfredo, additional, Galatola, Martina, additional, Castilljeo, Gemma, additional, Crespo Escobar, Paula, additional, Gyimesi, Judith, additional, Hartman, Corina, additional, Kolacek, Sanja, additional, Koletzko, Sybille, additional, Korponay-Szabo, Ilma, additional, Mearin, Maria Luisa, additional, Meijer, Caroline, additional, Pieścik-Lech, Malgoscia, additional, Polanco, Isabel, additional, Ribes-Koninckx, Carmen, additional, Shamir, Raanan, additional, Szajewska, Hania, additional, Troncone, Riccardo, additional, and Greco, Luigi, additional

Published
2020
Full Text
View/download PDF

22. Factores ambientales de riesgo asociados a la enfermedad celiaca en población con susceptibilidad genética

Author

Crespo Escobar, Paula, Ribes Koninckx, Carmen, Cañete Nieto, Adela, and Departament de Pediatria, Obstetrícia i Ginecologia

Subjects
Enfermedad celiaca, Pediatría, Trigo, Gluten
Abstract

Introducción y justificación: La enfermedad celiaca (EC), es un trastorno sistémico permanente, provocado por una reacción inmunitaria activada por la ingestión de gluten y proteínas relacionadas, que se da en personas portadoras del HLA-DQ2 y/o DQ8. Este genotipo está ampliamente distribuido en población general, sin embargo solo 1/3 de los individuos genéticamente susceptibles acaba desarrollando una EC, lo que sugiere la necesidad de determinados factores ambientales cuyo papel sería fundamental en el desarrollo de la enfermedad. Numerosos estudios observacionales han sugerido que estos factores pueden ser la cantidad de gluten y el tipo de trigo (hexaploide o tetraploide) ingeridos en los primeros años de vida. Objetivos: En base a esta hipótesis evaluar el impacto de la cantidad de gluten consumida y tipo de trigo consumido durante los primeros años de vida, en el desarrollo de la EC. Pacientes: Los sujetos de este estudio, pertenecen a la cohorte del Proyecto Europeo PreventCD, cuyo principal objetivo era analizar la incidencia de EC a los 3 años, tras la introducción precoz del gluten, entre los 4 y 6 meses, en una cohorte Europea, compuesta por sujetos con riesgo genético, reclutados desde el nacimiento y seguidos prospectivamente, al menos hasta los 3 años. Para este trabajo, se seleccionaron solo aquellos que tenían disponibles los datos del consumo de gluten desde el nacimiento hasta los 36 meses, que fueron un total de 715 sujetos, de Alemania, España, Hungría, Italia y Países Bajos. Los pacientes se reclutaron al nacer, y se siguieron periódicamente, realizándose exploración física, determinación de los niveles de anticuerpos anti-TG2, IgA total y evaluación de síntomas característicos de EC. Los sujetos se siguieron hasta los 6 años. Metodología: Para la cuantificación del gluten, se utilizaron registros alimentarios y cuestionarios de frecuencia de consumo, previamente desarrollados y validados para tal fin. En estas herramientas se recogía tanto la cantidad de productos como tipo y marca, para estimar cantidad de gluten y tipo de trigo consumido por cada individuo. Finalmente, para el análisis de riesgo de desarrollo de EC, se realizaron 2 modelos de regresión de Cox multivariable de riesgos proporcionales, ajustando para las siguientes variables: país, género, grupo de intervención (gluten o placebo), grupo de riesgo HLA, patrón de consumo de gluten (que incluía la cantidad total de gluten consumido de cada sujeto), tipo de trigo consumido, y la interacción entre el grupo de riesgo HLA y el patrón de consumo de gluten. Resultados: Respecto a la cantidad de gluten, a partir de los 11 meses, cuando por protocolo se permitió un consumo de gluten libre, se observaron diferencias estadísticamente significativas en la comparación múltiple entre todos los países y a todas las edades (p

Published
2017

24. Innovative approach for self-management and social welfare of children with cystic fibrosis in Europe: development, validation and implementation of an mHealth tool (MyCyFAPP)

Author

Calvo-Lerma, Joaquim, primary, Martinez-Jimenez, Celia P, additional, Lázaro-Ramos, Juan-Pablo, additional, Andrés, Ana, additional, Crespo-Escobar, Paula, additional, Stav, Erlend, additional, Schauber, Cornelia, additional, Pannese, Lucia, additional, Hulst, Jessie M, additional, Suárez, Lucrecia, additional, Colombo, Carla, additional, Barreto, Celeste, additional, de Boeck, Kris, additional, and Ribes-Koninckx, Carmen, additional

Published
2017
Full Text
View/download PDF

25. Development and validation of two food frequency questionnaires to assess gluten intake in children up to 36 months of age

Author

Crespo Escobar, Paula, Calvo Lerma, Joaquim, Hervás Marín, David, Donat Aliaga, Ester, Masip Simó, Etna, Polo Miquel, Begoña, and Ribes Koninckx, Carmen

Subjects
Español, Enfermedad celiaca, Food frequency questionnaire, Celiac disease, Cuestionario de frecuencia de consumo, Spanish, Children, Niños, Gluten
Abstract

Background and objective: precise information on gluten consumption is crucial for specifically studying the impact of gluten introduction and gluten intake in celiac disease development. Our aim was to develop and validate tools (food frequency questionnaires, FFQs) for the assessment of gluten consumption in Spanish children aged 7-36 months. Methods: a total of 342 children, who attended primary healthcare centers for routine health surveys or La Fe Hospital for minor health problems as well as healthy children (recruited in nurseries and primary schools) participated in this survey. We have developed two different FFQs (one for 7-12 months and other for 13-36 months). For validation, results from two FFQs were compared with results of 2-day food records and also with the gold standard 7-day records. The mean gluten intake obtained by the 2DR vs. FFQ and the 7DR vs. FFQ, were compared using the Bland Altman plot method and also Lin's concordance correlation coefficient. Results: we found a good agreement between our FFQs and the 2DR and 7DR according to the results of both the Bland-Altman plots and Lin's concordance correlation coefficient. Conclusions: our two new FFQs are therefore the only validated questionnaires available to determine gluten consumption in Spanish children. They are user-friendly and offer excellent instruments to assess gluten intake in children up to 36 months of age. Antecedentes y objetivos: una información precisa sobre el consumo de gluten es muy importante para estudiar el verdadero impacto de la introducción y la ingesta de gluten en el desarrollo de la enfermedad celiaca. El objetivo del estudio fue desarrollar y validar herramientas (cuestionarios de frecuencia de consumo, CFC) para evaluar el consumo de gluten en niños con edades comprendidas entre los 7 y 36 meses. Métodos: se incluyeron un total de 342 niños reclutados en el Hospital Universitario y Politécnico de La Fe, así como en guarderías y escuelas de primaria con problemas menores de salud. Se desarrollaron dos CFC diferentes (uno para niños de 7 a 12 meses y otro para niños de 13 a 36 meses). Para su validación, los resultados obtenidos con los CFC se compararon con un registro alimentario de dos días (2RA) y también con un registro alimentario de soete días (7RA), considerado el "estándar de oro". La ingesta media de gluten obtenida de la comparación del 2RA vs. CFC y de 7RA vs. CFC fueron comparadas usando el método de Bland Altman plot y también el coeficiente de correlación de concordancia de Lin's. Resultados: de acuerdo a los resultados de los dos métodos estadísticos usados para la validación, se encontró una buena correlación entre los CFC y los registros alimentarios de dos y siete días, lo que indica que los CFC son fiables para la evaluación de la ingesta de gluten. Conclusiones: estos dos nuevos CFC son los únicos validados y disponibles en España para la evaluación de la ingesta de gluten. Además, son herramientas útiles y fáciles de usar para el cálculo del consumo de gluten en niños de hasta tres años de edad.

Published
2015

26. Clinical validation of an evidence-based method to adjust Pancreatic Enzyme Replacement Therapy through a prospective interventional study in paediatric patients with Cystic Fibrosis.

Author

Calvo-Lerma, Joaquim, Hulst, Jessie, Boon, Mieke, Colombo, Carla, Masip, Etna, Ruperto, Mar, Fornés-Ferrer, Victoria, van der Wiel, Els, Claes, Ine, Garriga, Maria, Roca, Maria, Crespo-Escobar, Paula, Bulfamante, Anna, Woodcock, Sandra, Martínez-Barona, Sandra, Andrés, Ana, de Boeck, Kris, Ribes-Koninckx, Carmen, and null, null

Subjects
CYSTIC fibrosis, PANCREATIC enzymes, LONGITUDINAL method
Abstract

Background: A method to adjust Pancreatic Enzyme Replacement Therapy in Cystic Fibrosis is not currently available. Objectives: To assess the in vivo efficacy of a method to adjust the dose of enzymatic supplement in CF extrapolated from previous in vitro digestion studies (theoretical optimal dose, TOD). Secondly, to assess how individual patient characteristics influence the expected coefficient of fat absorption (CFA) and thus to identify an individual correction factor to improve TOD. Methods: A prospective interventional study in 43 paediatric patients with CF from 5 European centres. They followed a 24h fixed diet with the theoretical optimal dose for each meal. Faecal collection was carried out between colorimetric markers in order to include all the faeces corresponding to the fixed diet. Beta regression models were applied to assess the associations of individual patient characteristics with the CFA. Results: Median CFA was 90% (84, 94% 1st, 3rd Q.) with no significant differences among centres. Intestinal transit time was positively associated with CFA (p = 0.007), but no statistical associations were found with and age, gender, phenotype or BMI. Regression model showed no improvement of the in vitro predicted theoretical optimal dose when taking individual patient characteristics into account. Conclusion: Strict adherence to the theoretical optimal dose of enzymatic supplement for a prescribed meal, led to median CFA levels at the clinical target of 90% with a low variability between patients. The proposed method can be considered as a first approach for an evidence-based method in PERT dosing based on food characteristics. Results have to be confirmed in free dietary settings. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

27. Innovative approach for self-management and social welfare of children with cystic fibrosis in Europe: development, validation and implementation of an mHealth tool (MyCyFAPP)

Author

Universitat Politècnica de València. Departamento de Tecnología de Alimentos - Departament de Tecnologia d'Aliments, Universitat Politècnica de València. Instituto Universitario de Aplicaciones de las Tecnologías de la Información - Institut Universitari d'Aplicacions de les Tecnologies de la Informació, European Commission, Generalitat Valenciana, Calvo-Lerma, Joaquim, Martinez-Jimenez, Celia P., Lazaro Ramos, Juan Pablo, Andrés Grau, Ana María, Crespo-Escobar, Paula, Stav, Erlen, Schauber, Cornelia, Pannese, Lucia, Hulst, Jessie M., Suarez, Lucrecia, Colombo, Carla, Barreto, Celeste, de Boeck, Kris, Ribes-Koninckx, Carmen, Universitat Politècnica de València. Departamento de Tecnología de Alimentos - Departament de Tecnologia d'Aliments, Universitat Politècnica de València. Instituto Universitario de Aplicaciones de las Tecnologías de la Información - Institut Universitari d'Aplicacions de les Tecnologies de la Informació, European Commission, Generalitat Valenciana, Calvo-Lerma, Joaquim, Martinez-Jimenez, Celia P., Lazaro Ramos, Juan Pablo, Andrés Grau, Ana María, Crespo-Escobar, Paula, Stav, Erlen, Schauber, Cornelia, Pannese, Lucia, Hulst, Jessie M., Suarez, Lucrecia, Colombo, Carla, Barreto, Celeste, de Boeck, Kris, and Ribes-Koninckx, Carmen

Abstract

[EN] Introduction For the optimal management of children with cystic fibrosis, there are currently no efficient tools for the precise adjustment of pancreatic enzyme replacement therapy, either for advice on appropriate dietary intake or for achieving an optimal nutrition status. Therefore, we aim to develop a mobile application that ensures a successful nutritional therapy in children with cystic fibrosis. Methods and analysis A multidisciplinary team of 12 partners coordinate their efforts in 9 work packages that cover the entire so-called `from laboratory to market¿ approach by means of an original and innovative co-design process. A cohort of 200 patients with cystic fibrosis aged 1¿17¿years are enrolled. We will develop an innovative, clinically tested mobile health application for patients and health professionals involved in cystic fibrosis management. The mobile application integrates the research knowledge and innovative tools for maximising self-management with the aim of leading to a better nutritional status, quality of life and disease prognosis. Bringing together different and complementary areas of knowledge is fundamental for tackling complex challenges in disease treatment, such as optimal nutrition and pancreatic enzyme replacement therapy in cystic fibrosis. Patients are expected to benefit the most from the outcomes of this innovative project. Ethics and dissemination The project is approved by the Ethics Committee of the coordinating organisation, Hospital Universitari La Fe (Ref: 2014/0484). Scientific findings will be disseminated via journals and conferences addressed to clinicians, food scientists, information and communications technology experts and patients. The specific dissemination working group within the project will address the wide audience communication through the website (http://www.mycyfapp.eu), the social networks and the newsletter.

Published
2017

28. Development and validation of two food frequency questionnaires to assess gluten intake in children up to 36 months of age

Author

Crespo Escobar,Paula, Calvo Lerma,Joaquim, Hervás Marín,David, Donat Aliaga,Ester, Masip Simó,Etna, Polo Miquel,Begoña, and Ribes Koninckx,Carmen

Subjects
Food frequency questionnaire, Celiac disease, Spanish, Children, Gluten
Abstract

Background and objective: precise information on gluten consumption is crucial for specifically studying the impact of gluten introduction and gluten intake in celiac disease development. Our aim was to develop and validate tools (food frequency questionnaires, FFQs) for the assessment of gluten consumption in Spanish children aged 7-36 months. Methods: a total of 342 children, who attended primary healthcare centers for routine health surveys or La Fe Hospital for minor health problems as well as healthy children (recruited in nurseries and primary schools) participated in this survey. We have developed two different FFQs (one for 7-12 months and other for 13-36 months). For validation, results from two FFQs were compared with results of 2-day food records and also with the gold standard 7-day records. The mean gluten intake obtained by the 2DR vs. FFQ and the 7DR vs. FFQ, were compared using the Bland Altman plot method and also Lin's concordance correlation coefficient. Results: we found a good agreement between our FFQs and the 2DR and 7DR according to the results of both the Bland-Altman plots and Lin's concordance correlation coefficient. Conclusions: our two new FFQs are therefore the only validated questionnaires available to determine gluten consumption in Spanish children. They are user-friendly and offer excellent instruments to assess gluten intake in children up to 36 months of age.

Published
2015

29. Nutrition of infants and young children (one to three years) and its effect on later health: A systematic review of current recommendations (EarlyNutrition project)

Author

Zalewski, Bartłomiej Mateusz, primary, Patro, Bernadeta, additional, Veldhorst, Margriet, additional, Kouwenhoven, Stefanie, additional, Crespo Escobar, Paula, additional, Calvo Lerma, Joaquim, additional, Koletzko, Berthold, additional, van Goudoever, Johannes Bernard, additional, and Szajewska, Hania, additional

Published
2016
Full Text
View/download PDF

30. Optimal nutrition in lactating women and its effect on later health of offspring: A systematic review of current evidence and recommendations (EarlyNutrition project)

Author

de Waard, Marita, primary, Brands, Brigitte, additional, Kouwenhoven, Stefanie M. P., additional, Lerma, Joaquim Calvo, additional, Crespo-Escobar, Paula, additional, Koletzko, Berthold, additional, Zalewski, Bartlomiej M., additional, and van Goudoever, Johannes B., additional

Published
2016
Full Text
View/download PDF

31. Optimal nutrition in lactating women and its effect on later health of offspring: A systematic review of current evidence and recommendations (EarlyNutrition project).

Author

de Waard, Marita, Brands, Brigitte, Kouwenhoven, Stefanie M. P., Lerma, Joaquim Calvo, Crespo-Escobar, Paula, Koletzko, Berthold, Zalewski, Bartlomiej M., and van Goudoever, Johannes B.

Subjects
LACTATION, MATERNAL nutrition, INFANT health, DIETARY supplements, SYSTEMATIC reviews, METABOLIC syndrome
Abstract

Background: EarlyNutrition ( www.project-earlynutrition.eu ) is an international research consortium investigating the effects of early nutrition on metabolic programming.Objective: To summarize current evidence and standards, recommendations, guidelines, and regulations on nutrition or supplements in lactating women with emphasis placed on long-term health effects in offspring, including cardiovascular disease, hypertension, overweight/obesity, metabolic syndrome, diabetes, or glucose intolerance.Methods: Medline, Embase, selected databases and websites were searched for documents published between 2010 and 2015.Results: Thirteen documents met the inclusion criteria. Effects of maternal long-chain polyunsaturated fatty acid (LC-PUFA) supplementation on overweight/obesity or hypertension in offspring were assessed in 10 studies. One study described the effect of maternal vitamin D supplementation on overweight/obesity, and the remaining 2 studies assessed the effects of maternal probiotic/synbiotic supplementation during lactation on overweight/obesity or metabolic syndrome in their infants. Forty-one documents contained dietary recommendations on various macro- and micronutrients for lactating women, but without consideration of our long-term health outcomes in infants.Conclusion: Literature on nutrition of lactating women and its effect on their infants' later health with respect to metabolic programming outcomes appeared to be scarce, and focused mostly on supplementation of LC-PUFA's. No recent guidelines or recommendations were available, highlighting the significant research gaps regarding this topic. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

32. Nutrition of infants and young children (one to three years) and its effect on later health: A systematic review of current recommendations (EarlyNutrition project).

Author

Zalewski, Bartłomiej Mateusz, Patro, Bernadeta, Veldhorst, Margriet, Kouwenhoven, Stefanie, Crespo Escobar, Paula, Calvo Lerma, Joaquim, Koletzko, Berthold, van Goudoever, Johannes Bernard, and Szajewska, Hania

Subjects
INFANT nutrition, CHILD nutrition, CARDIOVASCULAR diseases risk factors, UNSATURATED fatty acids in human nutrition, FOOD chemistry
Abstract

Background. EarlyNutrition (www.project-earlynutrition.eu) is an international research project investigating the effects of early nutrition on metabolic programming. Objective. To summarize, by performing a systematic review, current standards, recommendations, guidelines, and regulations (hereafter, referred to as documents) on the nutrition of children up to three years of age. Special emphasis was placed on long-term effects of early nutrition, such as the risk of cardiovascular disease, hypertension, overweight, obesity, metabolic syndrome, diabetes, or glucose intolerance. Methods. MEDLINE, selected databases, and websites were searched for documents published between 2008 and January 2013. Results. Forty two documents met the inclusion criteria. The strongest and most consistent evidence for a protective, long-term effect was documented for breastfeeding. Also, limiting the intake of sodium and rapidly absorbed carbohydrates, use of a specific meal pattern, reducing the consumption of saturated fatty acids by replacing them with polyunsaturated fatty acids, and lowering the intake of trans fatty acids, seems beneficial. Many documents did not evaluate long-term outcomes of interest to us, or reported insufficient or imprecise data. Inconsistency in recommendations for some outcomes and research gaps were identified. Conclusions. Our findings may serve as a helpful tool in planning further research, preventive actions against important diet-related diseases, and guidelines improvement. [ABSTRACT FROM PUBLISHER]

Published
2017
Full Text
View/download PDF

33. DEVELOPMENT AND VALIDATION OF TWO FOOD FREQUENCY QUESTIONNAIRES TO ASSESS GLUTEN INTAKE IN CHILDREN UP TO 36 MONTHS OF AGE.

Author

Escobar, Paula Crespo, Lerma, Joaquim Calvo, Hervás Marín, David, Aliaga, Ester Donat, Masip Simó, Etna, Polo Miquel, Begoña, Ribes Koninckx, Carmen, Crespo Escobar, Paula, Calvo Lerma, Joaquim, Hervas Marin, David, Donat Aliaga, Ester, and Ribes Koninckx, Carmen

Subjects
*GLUTEN, *CHILD nutrition, *FOOD habits, *FOOD consumption, *QUESTIONNAIRES, *CELIAC disease in children, *CHILDREN, *CELIAC disease, *COMPARATIVE studies, *DIET, *RESEARCH methodology, *MEDICAL cooperation, *RESEARCH, *SURVEYS, *EVALUATION research, *FOOD diaries, *IMPACT of Event Scale, RESEARCH evaluation
Abstract

Background and Objective: precise information on gluten consumption is crucial for specifically studying the impact of gluten introduction and gluten intake in celiac disease development. Our aim was to develop and validate tools (food frequency questionnaires, FFQs) for the assessment of gluten consumption in Spanish children aged 7-36 months.Methods: a total of 342 children, who attended primary healthcare centers for routine health surveys or La Fe Hospital for minor health problems as well as healthy children (recruited in nurseries and primary schools) participated in this survey. We have developed two different FFQs (one for 7-12 months and other for 13-36 months). For validation, results from two FFQs were compared with results of 2-day food records and also with the gold standard 7-day records. The mean gluten intake obtained by the 2DR vs. FFQ and the 7DR vs. FFQ, were compared using the Bland Altman plot method and also Lin's concordance correlation coefficient.Results: we found a good agreement between our FFQs and the 2DR and 7DR according to the results of both the Bland-Altman plots and Lin's concordance correlation coefficient.Conclusions: our two new FFQs are therefore the only validated questionnaires available to determine gluten consumption in Spanish children. They are user-friendly and offer excellent instruments to assess gluten intake in children up to 36 months of age. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

34. Growth rate of coeliac children is compromised before the onset of the disease

Author

Caroline Meijer, Judith Gyimesi, Sybille Koletzko, Riccardo Troncone, Donatella Cielo, Alfredo Chiurazzi, Renata Auricchio, Sanja Kolaček, Corina Hartman, Malgoscia Pieścik-Lech, Martina Galatola, Ilma Rita Korponay-Szabó, Hania Szajewska, Dario Bruzzese, Carmen Ribes-Koninckx, Gemma Castilljeo, M. L. Mearin, Raanan Shamir, Paula Crespo Escobar, Isabel Polanco, Pio Stellato, Luigi Greco, Auricchio, Renata, Stellato, Pio, Bruzzese, Dario, Cielo, Donatella, Chiurazzi, Alfredo, Galatola, Martina, Castilljeo, Gemma, Crespo Escobar, Paula, Gyimesi, Judith, Hartman, Corina, Kolacek, Sanja, Koletzko, Sybille, Korponay-Szabo, Ilma, Mearin, Maria Luisa, Meijer, Caroline, Pieścik-Lech, Malgoscia, Polanco, Isabel, Ribes-Koninckx, Carmen, Shamir, Raanan, Szajewska, Hania, Troncone, Riccardo, and Greco, Luigi

Subjects
Male, Pediatrics, medicine.medical_specialty, growth, gastroenterology, Disease, Coeliac disease, Serology, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, medicine, Humans, Growth rate, Longitudinal Studies, Genetic risk, paediatric practice, Child, Growth Disorders, business.industry, Body Weight, Infant, Newborn, Infant, medicine.disease, Body Height, Celiac Disease, Case-Control Studies, Child, Preschool, Pediatrics, Perinatology and Child Health, 030211 gastroenterology & hepatology, Female, business, gastroenterology, growth, paediatric practice, Rate of growth
Abstract

IntroductionGrowth impairment has often been described in children who develop coeliac disease (CD). Based on data from the multicentre, longitudinal PreventCD study, we analysed the growth patterns of infants at genetic risk of CD, comparing those who developed CD by 6 years of age (CD ‘cases’, 113 infants) versus those who did not develop CD by 6 years (no CD ‘controls’, 831 infants).MethodsWeight and length/height were measured using a longitudinal protocol. Raw measurements were standardised, computing z-scores for length/height and weight; a linear mixed model was fitted to the data in order to compare the rate of growth in the two cohorts.ResultsNeither cases nor controls had significant growth failure. However, when the mean z-scores for weight and height were analysed, there was a difference between the two groups starting at fourth month of life. When the growth pattern in the first year was analysed longitudinally using mixed models, it emerged that children who develop CD had a significantly lower growth rate in weight z-score (−0.028/month; 95% CI −0.038 to −0.017; pConclusionThe growth of children at risk of CD rarely fell below ‘clinical standards’. However, growth rate was significantly lower in cases than in controls. Our data suggest that peculiar pathways of growth are present in children who develop CD, long before any clinical or serological signs of the disease appear.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results